Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27(Kip1)

Genes and Development

Volumn 11, Issue 18, 1997, Pages 2335-2346

  Casaccia Bonnefil, Patrizia ^a   Tikoo, Ravi ^a   Kiyokawa, Hiroaki ^b   Friedrich Jr , Victor ^c   Chao, Moses V ^a   Koff, Andrew ^b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Cell proliferation; CKI p27(Kip1); Differentiation; Oligodendrocyte progenitor cells

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; GLIA CELL; MOUSE; MYELINATION; NERVE CELL DIFFERENTIATION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; STEM CELL;

ANIMALIA;

EID: 0030922936     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.11.18.2335     Document Type: Article

References (70)

1. Agrawal, D., P. Hauser, F. McPherson, F. Dong, A. Garcia, and W.J. Pledger. 1996. Repression of p27Kip1 synthesis by platelet-derived growth factor in Balb/c 3T3 cells. Mol. Biol. Cell 8: 4327-4336.
2. Barres, B., M. Lazar, and M. Raff. 1994. A novel role for thyroid hormone, glucocorticoids, and retinoic acid in timing of oligodendrocyte development. Development 120: 1097-1108.
3. Bögler, O. and M. Noble. 1994. Measurement of time in oligodendrocyte-type-2 astrocyte (O-2A) progenitors is a cellular process distinct from differentiation of division. Dev. Biol. 162: 525-538.
4. Boudreau, N., Z. Werb, and M.J. Bissell. 1996. Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle. Proc. Natl. Acad. Sci. 93: 3509-3513.
5. Boulikas, T. 1995. Phosphorylation of transcription factors and control of the cell cycle. Crit. Rev. Eukaryot. Gene Expr. 5: 1-77.
6. Burne, J.F., J.K. Staple, and M.C. Raff. 1996. Glial cells are increased proportionally in transgenic optic nerves with increased numbers of axons. J. Neurosci. 16: 2064-2073.
7. Casaccia-Bonnefil, P., L. Aibel, and M.V. Chao. 1996. Central glial and neuronal populations display differential sensitivity to ceramide-dependent cell death. J. Neurosci. Res. 43: 382-389.
8. Coats, S., W.M. Flanagan, J. Nourse, and J.M. Roberts. 1996. Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle. Science 272: 877-880.
9. Cross, F.R. 1988. DAF1, a mutant gene affecting size control, pheromone arrest, and cell cycle kinetics of Saccharomyces cerevisiae. Mol. Biol. Cell. 8: 4675-4684.
10. Durand, B., F.B. Gao, and M. Raff. 1997. Accumulation of the cyclin-dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiation. EMBO J. 16: 306-317.
11. 1-S transcriptional program in Drosophilia. Development 120: 1503-1515.
12. Fero, M.L., M. Rivkin, M. Tasch, P. Porter, C.E. Carow, E. Firpo, K. Polyak, L.H. Tsai, V. Broudy, R.M. Perlmutter, K. Kaushansky, and J.M. Roberts. 1996. A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice. Cell 85: 733-744.
13. Firpo, E.J., A. Koff, M.J. Solomon, and J.M. Roberts. 1994. Inactivation of a Cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes. Mol. Cell. Biol. 14: 4889-4901.
14. Fisher, R.P. and D.O. Morgan. 1994. A novel cyclin associates with MO15/CDK7 to form the CDK activating kinase. Cell 78: 713-724.
15. Gard, A.L. and S.E. Pfeiffer. 1989. Oligodendrocyte progenitors isolated directly from developing telencephalon at a specific phenotypic stage: Myelinogenic potential in a defined environment. Development 106: 119-132.
16. _. 1990. Two proliferative stages of the oligodendrocyte lineage (A2B5+O4- and O4+GalC-) under different mitogenic control. Neuron 5: 615-625.
17. Guo, K., J. Wang, V. Andres, R.C. Smith, and K. Walsh. 1995. MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation. Mol. Cell. Biol. 15: 3823-3829.
18. Hara, E., R. Smith, D. Parry, H. Tahara, S. Stone, and G. Peters. 1996. Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence. Mol. Cell. Biol. 16: 859-867.
19. Harper, J.W., G.R. Adami, N. Wei, K. Keyomarsi, and S.J. Elledge. 1993. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75: 805-816.
20. Hauser, P.J., D. Agrawal, M. Flanagan, and W.J. Pledger. 1997. The role of p27Kip1 in the in vitro differentiation of murine keratinocytes. Cell Growth Differ. 8: 203-211.
21. Hengst, L. and S.I. Reed. 1996. Translational control of p27Kip1 during the cell cycle. Science 271: 1861-1864.
22. Hirai, H., M.F. Roussel, J.Y. Kato, R.A. Ashmun, and C.J. Sherr. 1995. Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6. Mol. Cell. Biol. 15: 2672-2681.
23. Hofbauer, R. and D.T. Denhardt. 1991. Cell cycle-regulated and proliferation stimulus-responsive genes. Crit. Rev. Eukaryot. Gene Expr. 1: 247-300.
24. Hoffman, E.S., L. Passoni, T. Crompton, T.M.J. Leu, D.G. Schatz, A. Koff, M.J. Owen, and A.C. Hayday. 1996. Productive T-cell receptor β-chain gene rearrangement: Coincident regulation of cell cycle and clonality during development in vivo. Genes & Dev. 9: 948-962.
25. Kato, J.Y. and C.J. Sherr. 1993. Inhibition of granulocyte differentiation by G1 cyclins D2 and D3 but not D1. Proc. Natl. Acad. Sci. 90: 11513-11517.
26. Kipreos, E.T., L.E. Lander, J.P. Wing, W.W. He, and E.M. Hedgecock. 1996. cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. Cell 86: 829-839.
27. Kiyokawa, H., R.D. Kineman, K.O. Manova-Todorova, V.C. Soares, E.S. Hoffman, M. Ono, D. Khanam, A.C. Hayday, L.A. Frohman, and A. Koff. 1996. Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27Kip1. Cell 85: 721-732.
28. Koff, A. 1995. The regulation of G1 progression in mammalian cells. In Future trends in endocrinology (ed. A. DeBellis and E. Shipani), pp. 207-216. Ares-Serona Symposia Publications, Rome, Italy.
29. Koff, A., A. Giordano, D. Desai, K. Yamashita, J.W. Harper, S. Elledge, T. Nishimoto, D.O. Morgan, B.R. Franza, and J.M. Roberts. 1992. Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle. Science 257: 1689-1694.
30. Kranenburg, O., V. Scharnhost, A.J. van der Eb, and A. Zantema. 1995. Inhibition of cyclin-dependent kinase activity triggers neuronal differentiation of mouse neuroblastoma cells. J. Cell Biol. 131: 227-234.
31. Lane, M.E., K. Sauer, K. Wallace, Y.N. Jan, C.F. Lehner, and H. Vaessin. 1996. Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophilia development. Cell 87: 1225-1235.
32. Lassar, A.B., S.X. Skapek, and B. Novitch. 1994. Regulatory mechanisms that coordinate skeletal muscle differentiation and cell cycle withdrawal. Curr. Opin. Cell Biol. 6: 788-794.
33. Lee, M.H., I. Reynisdóttir, and J. Massagué. 1995. Cloning of p57Kip2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes & Dev. 9: 639-649.
34. Lee, M.H., M. Nikolic, C.A. Baptista, E. Lai, L.H. Tsai, and J. Massaguá. 1996. The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons. Proc. Natl. Acad. Sci. 93: 3259-3263.
35. Liu, M., M.H. Lee, M. Cohen, M. Bommakanti, and L.P. Freedman. 1996. Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937. Genes & Dev. 10: 142-153.
36. Louis, J., E. Magal, D. Muir, M. Manthorpe, and S. Varon. 1992. CG-4, a new bipotential glial cell line from rat brain is capable of differentiating in vitro into either nature oligodendrocytes of type-2 astrocytes. J. Neurosci. Res. 31: 193-204.
37. Matsuoka, M., J.Y. Kato, R.P. Fisher, D.O. Morgan, and C.J. Sherr. 1994. Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase. Mol. Cell. Biol. 14: 7265-7275.
38. Matsuoka, S., M.C. Edwards, C. Bai, S. Parker, P. Zhang, A. Baldini, J.W. Harper, and S.J. Elledge. 1995. p57Kip2, a structurally distinct member of the p21Cip1 Cdk inhibitor family, is a candidate tumor suppressor gene. Genes & Dev. 9: 650-662.
39. Matsushime, H., M.E. Ewen, D.K. Strom, J.Y. Kato, S.K. Hanks, M.F. Roussel, and C.J. Sherr. 1992. Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins. Cell 71: 323-334.
40. McCarthy, K.D. and DeVellis, J. 1980. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J. Cell. Biol. 85: 890-902.
41. Medema, R.H., R.E. Herrera, F. Lam, and R.A. Weinberg. 1995. Growth suppression by p16INK4 requires functional retinoblastoma protein. Proc. Natl. Acad. Sci. 92: 6289-6293.
42. Meyerson, M. and E. Harlow. 1994. Identification of G1 kinase activity for cdk6, a novel cyclin D partner. Mol. Cell. Biol. 14: 2077-2086.
43. Millard, S.S., J.S. Yan, H. Nguyen, M. Pagano, H. Kiyokawa, and A. Koff. 1997. Enhanced ribosomal association of p27Kip1 mRNA is a mechanism contributing to accumulation during growth arrest. J. Biol. Chem. 272: 7093-7098.
44. Morgan, D.O. 1995. Principles of CDK regulation. Nature 374: 131-134.
45. Nakayama, K., N. Ishida, M. Shirane, A. Inomata, T. Inoue, N. Shishido, I. Horii, D.Y. Loh, and K-i. Nakayama. 1996. Mice lacking p27Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85: 707-720.
46. Nishiyama, A., X.-H. Lin, N. Giese, C.-H. Heldin, and W.B. Stallcup. 1996. Co-localization of NG2 proteoglycan and PDGF alpha receptor on O-2A progenitor cells in the developing rat brain. J. Neurosci. Res. 43: 299-314.
47. Noda, A., Y. Ning, S.F. Venable, O.M. Pereira-Smith, and J.R. Smith. 1994. Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. Cell Res. 211: 90-98.
48. Ohtusbo, M. and J.M. Roberts. 1993. Cyclin-dependent regulation of G1 in mammalian fibroblasts. Science 259: 1908-1912.
49. Pagano, M., S.W. Tam, A.M. Theodoras, P. Beer-Romero, G. Del Sal, V. Chau, P.R. Yew, G.F. Draetta, and M. Rolfe. 1995. Role of the ubiquitin proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 269: 682-685.
50. Parker, S.B., G. Eichele, P. Zhang, A. Rawls, A.T. Sands, A. Bradley, E.N. Olson, J.W. Harper, and S.J. Elledge. 1995. p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells. Science 267: 1024-1027.
51. Polyak, K., M.H. Lee, H. Erdjument-Bromage, A. Koff, J.M. Roberts, P. Tempst, and J. Massagué. 1994. Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78: 59-66.
52. Poulos, N.L., A.A. Farmer, K.W. Chan, and E.J. Stanbridge. 1996. Design of a novel bicistronic expression vector with demonstration of a p16INK4-induced G1-S block. Cancer Res. 56: 1719-1723.
53. Raff, M. 1989. Glial cell diversification in the rat optic nerve. Science 243: 1450-1455.
54. Raff, M.C., R.H. Miller, and M. Noble. 1983. A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on the culture medium. Nature 303: 390-396.
55. Raff, M.C., E.R. Abney, and J. Fok-Seang. 1985. Reconstruction of a developmental clock in vitro: A critical role for astrocytes in the timing of oligodendrocyte differentiation. Cell 42: 61-69.
56. Raff, M.C., L.E. Lillien, W.D. Richardson, J.F. Burne, and M.D. Noble. 1988. Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture. Nature 333: 562-565.
57. Raff, M.C., B.A. Barres, J.F. Burne, H.S. Coles, Y. Ishizaki, and M.D. Jacobson. 1993. Programmed cell death and the control of cell survival: Lessons from the nervous system. Science 262: 695-700.
58. 1-to-S transition. Mol. Cell. Biol. 15: 3463-3469.
59. Kip1 coordinate their inhibitory interactions with cdk4 and cdk2. Genes & Dev. 11: 492-503.
60. Russo, A.A., P.D. Jeffrey, A.K. Patten, J. Massagué, and N.P. Pavletich. 1996. Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex. Nature 382: 325-331.
61. Sheaff, R.J., M. Groudine, M. Gordon, J.M. Roberts, and B.E. Clurman. 1997. Cyclin E-Cdk2 is a regulator of p27Kip1. Genes & Dev. 11: 1464-1478.
62. 1 cyclin-dependent kinases. Genes &. Dev. 9: 1149-1163.
63. Skapek, S.X., J. Rhee, D.B. Spicer, and A.B. Lassar. 1995. Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase. Science 267: 1022-1024.
64. Soos, T.J., H. Kiyokawa, J.S. Yan, M.S. Rubin, A. Giordano, A. DeBlasio, S. Bottega, B. Wong, J. Mendelsohn, and A. Koff. 1996. Formation of p27-CDK complexes during the human mitotic cell cycle. Cell Growth Differ. 7: 135-146.
65. Stein, G.H. and V. Dulic. 1995. Origins of G1 arrest in senescent human fibroblasts. Bioessays 17: 537-543.
66. Tahara, H., E. Sato, A. Noda, and T. Ide. 1995. Increase in expression level of p21sdi1/cip1/waf1 with increasing division age in both normal and SV40-transformed human fibroblasts. Oncogene 10: 835-840.
67. Temple, S. and M.C. Raff. 1985. Differentiation of a bipotential glial progenitor cell in single cell microculture. Nature 313: 223-225.
68. Tikoo, R., P. Casaccia-Bonnefil, M.V. Chao, and A. Koff. 1997. Changes in cyclin-dependent kinase 2 and p27Kip accompany glial cell differentiation of central glial-4 cells. J. Biol. Chem. 272: 442-447.
69. 1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78: 67-74.
70. Xiong, Y., H. Zhang, and D. Beach. 1992. D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA. Cell 71: 504-514.