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Volumn 19, Issue 5, 2000, Pages 331-343

COX-2-specific inhibitors - The emergence of a new class of analgesic and anti-inflammatory drugs

Author keywords

Celecoxib; Cox 2 specific inhibitors; Inflammatory disease; NSAID; Rofecoxib

Indexed keywords

ACETYLSALICYLIC ACID; CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; ETODOLAC; IBUPROFEN; METHOTREXATE; NABUMETONE; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN; RIFAMPICIN; ROFECOXIB; WARFARIN;

EID: 0033802911     PISSN: 07703198     EISSN: None     Source Type: Journal    
DOI: 10.1007/s100670070024     Document Type: Review
Times cited : (117)

References (131)
  • 5
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
    • (1971) Nature New Biol , vol.231 , pp. 232-235
    • Vane, J.1
  • 8
    • 0024558198 scopus 로고
    • The eicosanoids and their biochemical mechanisms of action
    • (1989) Biochem J , vol.259 , pp. 315-324
    • Smith, W.L.1
  • 9
    • 0028044609 scopus 로고
    • Towards a better aspirin
    • (1994) Nature , vol.367 , pp. 215-216
    • Vane, J.1
  • 12
    • 0030000385 scopus 로고    scopus 로고
    • The role of antiinflammatory drugs in the prevention and treatment of Alzheimer's disease
    • (1996) Annu Rev Med , vol.47 , pp. 401-411
    • Breitner, J.C.S.1
  • 14
    • 0030013660 scopus 로고    scopus 로고
    • Prevention of gastrointestinal cancer - The potential role of NSAIDs in colorectal cancer
    • (1996) Schweiz Med Wchschr , vol.126 , pp. 801-812
    • Luk, G.D.1
  • 16
    • 0025751563 scopus 로고
    • Swedish aspirin low-dose trial (SALT) of 75 mg aspirin as secondary prophylaxis after cerebovascular ischaemic events
    • (1991) Lancet , vol.338 , pp. 1345-1349
  • 30
    • 0026744831 scopus 로고
    • Purification and characterisation of a novel, distinct isoform of prostaglandin endoperoxide synthase induced by human chorionic gonadotropin in granulosa cells of rat preovulatory follicles
    • (1992) J Biol Chem , vol.267 , pp. 6382-6388
    • Sirois, J.1    Richards, J.S.2
  • 48
    • 0029758675 scopus 로고    scopus 로고
    • Nimesulide: A selective cyclooxygenase 2 inhibitor antiinflammatory drug
    • (1996) Drugs Today , vol.32 , Issue.SUPPL. D , pp. 1-23
    • Rabasseda, X.1
  • 49
    • 0025019780 scopus 로고
    • Non-steroidal anti-inflammatory drugs and ulcers: Facts and figures multiply but do they add up?
    • (1990) Br Med J , vol.300 , pp. 278-284
    • Hawkey, C.J.1
  • 52
    • 0014426036 scopus 로고
    • Gastric ulcer, duodenal ulcer and gastric carcinoma: A case-control study of certain social and environmental factors
    • (1968) Med J Aust , vol.2 , Issue.25 , pp. 1132-1136
    • Gillies, M.1    Skyring, A.2
  • 54
    • 0002277454 scopus 로고
    • Analgesic-antipyretics and inflammatory agents: Drugs employed in the treatment of rheumatid arthritis and gout
    • Gillman A, Rall RW, Nies AS, Taylor P, eds. The pharmacological basis of therapeutics. New York: Pergamon Press
    • (1990) , pp. 638-681
    • Insel, P.A.1
  • 55
    • 0028327671 scopus 로고
    • Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs
    • (1994) Lancet , vol.343 , pp. 769-772
    • Garcia Rodrigues, L.A.1    Jick, H.2
  • 63
    • 0028843881 scopus 로고
    • Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
    • (1995) Cell , vol.83 , Issue.3 , pp. 483-492
    • Langenbach, R.1    Morham, S.G.2    Tiano, H.F.3
  • 74
    • 0018656916 scopus 로고
    • Effect of prostaglandin E2 on chloride transport across the rabbit thick ascending limb of Henle. Selective inhibitions of the medullary portion
    • (1979) J Clin Invest , vol.64 , pp. 495-502
    • Stokes, J.B.1
  • 75
    • 0018080134 scopus 로고
    • Role of prostaglandin E (PGE) in the modulation of action of vasopressin on water flow in the urinary bladder of the toad and mammalian kidney
    • (1978) J Membrane Biol , vol.40 , pp. 297-304
    • Orloff, J.1    Zusman, R.2
  • 76
    • 0025390545 scopus 로고
    • Assessing the benefits and risks of drugs. The example of NSAIDs
    • (1990) Aust Fam Phys , vol.19 , Issue.3 , pp. 78-83
    • Henry, D.1
  • 77
    • 13444266910 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: Identification of a 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-prazol-l-yl] benzenesulfonamide (SC-58635, celecoxib)
    • (1997) J Med Chem , vol.40 , pp. 1347-1365
    • Penning, T.D.1    Talley, J.J.2    Bertenshaw, S.R.3
  • 78
    • 0000949266 scopus 로고    scopus 로고
    • Specific COX-2 inhibitors: From bench to bedside
    • Vane J, Botting J, eds. Selective COX-2 inhibitors: Pharmacology, clinical effects and therapeutic potential, London: William Harvey Press
    • (1997) , pp. 127-133
    • Isakson, P.1    Zweifel, B.2    Masferrer, J.3
  • 84
    • 0000036055 scopus 로고    scopus 로고
    • Selective inhibition of cyclooxygenase-2 (COX-2) with MG-0966 (250 mg qd) is associated with less gastroduodenal damage than aspirin (ASA) 650 mg qid or ibuprofen (IBU) 800 mg tid
    • (1997) Gastroenterology , vol.112
    • Lanza, F.1    Simon, T.2    Quan, H.3
  • 87
    • 0030849721 scopus 로고    scopus 로고
    • Pain management in osteoarthritis: The role of COX-2 inhibitors
    • (1997) J Rheumatol , vol.24 , pp. 20-24
    • Lane, N.E.1
  • 95
    • 0001305554 scopus 로고    scopus 로고
    • MK-0966, a specific COX-2 inhibitor, has clinical efficacy comparable to ibuprofen in the treatment of knee and hip osteoarthritis (OA) in a six-week controlled clinical trial
    • (1998) Arthritis Rheum , vol.41
    • Saag, K.1    Fisher, C.2    Mckay, J.3
  • 96
    • 0001305554 scopus 로고    scopus 로고
    • MK-0966, a specific COX-2 inhibitor, has clinical efficacy comparable to diclofenac in the treatment of knee and hip osteoarthritis (OA) in a 26-week controlled clinical trial
    • (1998) Arthritis Rheum , vol.41
    • Cannon, G.1    Caldwell, J.2    Holt, P.3
  • 97
    • 0000036055 scopus 로고    scopus 로고
    • Selective inhibition of cyclooxygenase-2 (COX-2) with MK-0966 (250 mg qd) is associated with less gastroduodenal damage than aspirin (ASA) 650 mg qid or ibuprofen (IBU) 800 mg tid
    • (1997) Gastroenterology , vol.112
    • Lanza, F.1    Simon, T.2    Quan, H.3
  • 98
    • 0000402103 scopus 로고    scopus 로고
    • COX-2 specific inhibition with MK-0966 or 50 mg qd over 4 weeks does not increase fecal blood loss: A controlled study with placebo or ibuprofen 800 mg tid
    • (1998) Am J Gastroenterol , vol.93
    • Hunt, R.1    Bowen, B.2    James, C.3
  • 108
    • 0032006784 scopus 로고    scopus 로고
    • Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis
    • (1998) Cancer Res , vol.58 , pp. 409-412
    • Kawamori, T.1    Rao, C.V.2
  • 115
    • 0000920292 scopus 로고    scopus 로고
    • Amyloid-β peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: A proinflammatory pathway in Alzheimer's disease
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 5296-5301
    • Yan, S.D.1    Zhu, D.2    Fu, J.3
  • 118
    • 0029740064 scopus 로고    scopus 로고
    • Localization of prostaglandin H synthase typ 2 protein and mRNA in term human fetal membranes and decidua
    • (1996) J Endocrinol , vol.150 , pp. 497-503
    • Gibb, W.1    Sun, M.2
  • 119
    • 0007809517 scopus 로고    scopus 로고
    • Personal communication, Talley JJ, Searle. Valdecoxib, a second generation COX-2 inhibitor
  • 124
    • 0033535606 scopus 로고    scopus 로고
    • Synthesis, structure-activity relationsships, and in vivo evaluations of substituted ditert-butylphenoles as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 2. 1,3,4-and 1,2,4-thiadiazole series
    • (1999) J Med Chem , vol.42 , pp. 1161-1169
    • Song, Y.1    Connor, D.T.2    Secrel, A.D.3
  • 125
    • 0033535514 scopus 로고    scopus 로고
    • Synthesis, structureactivity relationsships, and in vivo evaluations of substituted di-tert-butylphenoles as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series
    • (1999) J Med Chem , vol.42 , pp. 1151-1160
    • Song, Y.1    Connor, D.T.2    Doubleday, R.3
  • 129
    • 13444266910 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: Identification of 4-[5(4-methylphenyl)-3-(trifluoromethyl)- 1H-pyrazol- 1-yl]benzenesulfonamide (SC-58635, celecoxib)
    • (1997) J Med Chem , vol.40 , pp. 1347-1365
    • Penning, T.D.1    Talley, J.J.2    Bertenshaw, S.R.3
  • 131
    • 13344261416 scopus 로고    scopus 로고
    • Diarylspiro[2,4]heptenes as orally active, highly selective cyclooxygenase-2 inhibitors: Synthesis and structure-activity relationships
    • (1996) J Med Chem , vol.39 , pp. 253-266
    • Huang, H.C.1    Li, J.J.2    Garland, D.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.