TNFα processing enzyme inhibitors prevent aspirin-induced TNFα release and protect against gastric mucosal injury in rats

Alimentary Pharmacology and Therapeutics

Volumn 12, Issue 11, 1998, Pages 1139-1153

  Fiorucci, S ^a,b   Antonelli, E ^a   Migliorati, G ^a   Santucci, L ^a   Morelli, O ^a   Federici, B ^a   Morelli, A ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b POLICLINICO MONTELUCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

8 BROMO CYCLIC AMP; ACETYLSALICYLIC ACID; BB 3103; CALCIUM ION; EDETIC ACID; ENZYME INHIBITOR; INTERLEUKIN 10; IONOMYCIN; LIPOPOLYSACCHARIDE; LISOFYLLINE; MESSENGER RNA; PROSTAGLANDIN E2; TAPI 2; THAPSIGARGIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; DRUG DERIVATIVE; HYDROXAMIC ACID; LISOFYLLINE 4,5 DIOL; LISOFYLLINE 4,5-DIOL; NONSTEROID ANTIINFLAMMATORY AGENT; PENTOXIFYLLINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE RELEASE; CYTOTOXICITY; INTRAPERITONEAL DRUG ADMINISTRATION; MACROPHAGE; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; RNA TRANSCRIPTION; STOMACH EPITHELIUM; STOMACH MUCOSA LESION; TRANSCRIPTION INITIATION; ANIMAL; CELL CULTURE; DRUG EFFECT; METABOLISM; NORTHERN BLOTTING; STOMACH MUCOSA; WISTAR RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; BLOTTING, NORTHERN; CELLS, CULTURED; EDETIC ACID; GASTRIC MUCOSA; HYDROXAMIC ACIDS; MACROPHAGES; MALE; MICE; PENTOXIFYLLINE; RATS; RATS, WISTAR; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031593468     PISSN: 02692813     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2036.1998.00409.x     Document Type: Article

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