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Volumn 11, Issue 4, 1999, Pages 283-292

Regulation of naive T cell differentiation by varying the potency of TCR signal transduction

Author keywords

Calcium; T cell differentiation; TCR signal transduction; Th1; Th2

Indexed keywords

T LYMPHOCYTE RECEPTOR;

EID: 0033178513     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1006/smim.1999.0184     Document Type: Article
Times cited : (85)

References (51)
  • 1
    • 0032033419 scopus 로고    scopus 로고
    • Cytokines induce the development of functionally heterogeneous T helper cell subsets
    • O'Garra A. Cytokines induce the development of functionally heterogeneous T helper cell subsets. Immunity. 8:1998;275-283.
    • (1998) Immunity , vol.8 , pp. 275-283
    • O'Garra, A.1
  • 2
  • 3
    • 0031727316 scopus 로고    scopus 로고
    • Thymocyte selection: Not by TCR alone
    • Amsen D., Kruisbeek A.M. Thymocyte selection: not by TCR alone. Immunol Rev. 165:1998;209-229.
    • (1998) Immunol Rev , vol.165 , pp. 209-229
    • Amsen, D.1    Kruisbeek, A.M.2
  • 4
    • 0029988961 scopus 로고    scopus 로고
    • MHC Class II-specific T cells can develop in the CD8 lineage when CD4 is absent
    • Matechak E.O., Killeen N., Hedrick S.M., Fowlkes B.J. MHC Class II-specific T cells can develop in the CD8 lineage when CD4 is absent. Immunity. 4:1996;337-347.
    • (1996) Immunity , vol.4 , pp. 337-347
    • Matechak, E.O.1    Killeen, N.2    Hedrick, S.M.3    Fowlkes, B.J.4
  • 5
    • 0025288654 scopus 로고
    • Evidence implicating utilization of different T cell receptor-associated signaling pathways by Th1 and Th2 clones
    • Gajewski T.F., Schell S.R., Fitch F.W. Evidence implicating utilization of different T cell receptor-associated signaling pathways by Th1 and Th2 clones. J Immunol. 144:1990;4110-4120.
    • (1990) J Immunol , vol.144 , pp. 4110-4120
    • Gajewski, T.F.1    Schell, S.R.2    Fitch, F.W.3
  • 7
    • 0025667152 scopus 로고
    • CAMP inhibits induction of interleukin 2 but not of interleukin 4 in T cells. Proc Natl
    • Novak T.J., Rothenberg E.V. cAMP inhibits induction of interleukin 2 but not of interleukin 4 in T cells. Proc Natl. Acad Sci (USA). 87:1990;9353-9357.
    • (1990) Acad Sci (USA) , vol.87 , pp. 9353-9357
    • Novak, T.J.1    Rothenberg, E.V.2
  • 8
    • 0028167459 scopus 로고
    • Anergy of Th0 helper T lymphocytes induces downregulation of Th1 characteristics and a transition to a Th2-like phenotype
    • Gajewski T.F., Lancki D.W., Stack R., Fitch F.W. Anergy of Th0 helper T lymphocytes induces downregulation of Th1 characteristics and a transition to a Th2-like phenotype. J Exp Med. 179:1994;481-491.
    • (1994) J Exp Med , vol.179 , pp. 481-491
    • Gajewski, T.F.1    Lancki, D.W.2    Stack, R.3    Fitch, F.W.4
  • 9
    • 0028867139 scopus 로고
    • Early activation signal transduction pathways of Th1 and Th2 cell clones stimulated with anti-CD3. Roles of protein tyrosine kinases in the signal for IL-2 and IL-4 production
    • Tamura T., Nakano H., Nagase H., Morokata T., Igarashi O., Oshimi Y., Miyazaki S., Nariuchi H. Early activation signal transduction pathways of Th1 and Th2 cell clones stimulated with anti-CD3. Roles of protein tyrosine kinases in the signal for IL-2 and IL-4 production. J Immunol. 155:1995;4692-4701.
    • (1995) J Immunol , vol.155 , pp. 4692-4701
    • Tamura, T.1    Nakano, H.2    Nagase, H.3    Morokata, T.4    Igarashi, O.5    Oshimi, Y.6    Miyazaki, S.7    Nariuchi, H.8
  • 10
    • 0031205443 scopus 로고    scopus 로고
    • Selective loss of the calcium ion signaling pathaway in T cells maturing toward a T helper 2 phenotype
    • Sloan-Lancaster J., Steinberg T.H., Allen P.M. Selective loss of the calcium ion signaling pathaway in T cells maturing toward a T helper 2 phenotype. J Immunol. 159:1997;1160-1168.
    • (1997) J Immunol , vol.159 , pp. 1160-1168
    • Sloan-Lancaster, J.1    Steinberg, T.H.2    Allen, P.M.3
  • 11
    • 0032524957 scopus 로고    scopus 로고
    • Partial TCR signals delivered by FcR-nonbinding anit-CD3 monoclonal antibodies differentially regulate individual Th subsets
    • Smith J.A., Tang Q., Bluestone J.A. Partial TCR signals delivered by FcR-nonbinding anit-CD3 monoclonal antibodies differentially regulate individual Th subsets. J Immunol. 160:1998;4841-4849.
    • (1998) J Immunol , vol.160 , pp. 4841-4849
    • Smith, J.A.1    Tang, Q.2    Bluestone, J.A.3
  • 16
    • 0031573513 scopus 로고    scopus 로고
    • Distinct biochemical signals characterize agonist and altered peptide ligand-induced differentiation of naive CD4 T cells into Th1 and Th2 subsets
    • Boutin Y., Leitenberg D., Tao X., Bottomly K. Distinct biochemical signals characterize agonist and altered peptide ligand-induced differentiation of naive CD4 T cells into Th1 and Th2 subsets. J Immunol. 159:1997;5802-5809.
    • (1997) J Immunol , vol.159 , pp. 5802-5809
    • Boutin, Y.1    Leitenberg, D.2    Tao, X.3    Bottomly, K.4
  • 17
    • 0029933309 scopus 로고    scopus 로고
    • Altered peptide ligand-induced partial T cell activation molecular mechanisms and role in T cell biology
    • Sloan-Lancaster J., Allen P. Altered peptide ligand-induced partial T cell activation molecular mechanisms and role in T cell biology. Annu Rev Immunol. 14:1996;1-27.
    • (1996) Annu Rev Immunol , vol.14 , pp. 1-27
    • Sloan-Lancaster, J.1    Allen, P.2
  • 18
    • 0032145326 scopus 로고    scopus 로고
    • CD4 regulation of T cell receptor signaling and T cell differentiaion following stimulation with peptides of different affinites for the T cell receptor
    • Leitenberg D., Boutin Y., Constant S., Bottomly K. CD4 regulation of T cell receptor signaling and T cell differentiaion following stimulation with peptides of different affinites for the T cell receptor. J Immunol. 161:1998;1194-1203.
    • (1998) J Immunol , vol.161 , pp. 1194-1203
    • Leitenberg, D.1    Boutin, Y.2    Constant, S.3    Bottomly, K.4
  • 19
    • 0032532650 scopus 로고    scopus 로고
    • High antigen density and IL-2 are required for generation of CD4 effectors secreting Th1 rather than Th0 cytokines
    • Rogers P.R., Huston G., Swain S.L. High antigen density and IL-2 are required for generation of CD4 effectors secreting Th1 rather than Th0 cytokines. J Immunol. 161:1998;3844-3852.
    • (1998) J Immunol , vol.161 , pp. 3844-3852
    • Rogers, P.R.1    Huston, G.2    Swain, S.L.3
  • 21
    • 0032555904 scopus 로고    scopus 로고
    • A signal transducer and activator of transcription (Stat) 4-independent pathway for the development of T helper type 1 cells
    • Kaplan M.H., Wurster A.L., Grusby M.J. A signal transducer and activator of transcription (Stat) 4-independent pathway for the development of T helper type 1 cells. J Exp Med. 188:1998;1191-1196.
    • (1998) J Exp Med , vol.188 , pp. 1191-1196
    • Kaplan, M.H.1    Wurster, A.L.2    Grusby, M.J.3
  • 23
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NFAT family: Regulation and function
    • Rao A., Luo C., Hogan P.G. Transcription factors of the NFAT family: regulation and function. Annu Rev Immunol. 15:1997;707-747.
    • (1997) Annu Rev Immunol , vol.15 , pp. 707-747
    • Rao, A.1    Luo, C.2    Hogan, P.G.3
  • 24
    • 0026758278 scopus 로고
    • High levels of IL-2 alter signal transduction in cloned IL-4 producing CD4 T cells
    • Wolff H., Novak T., Shaw A., Dianzani U., Janeway C.A.J. High levels of IL-2 alter signal transduction in cloned IL-4 producing CD4 T cells. J Immunol. 149:1992;2996-3002.
    • (1992) J Immunol , vol.149 , pp. 2996-3002
    • Wolff, H.1    Novak, T.2    Shaw, A.3    Dianzani, U.4    Janeway, C.A.J.5
  • 25
    • 0032480279 scopus 로고    scopus 로고
    • Three-dimensional segregation of supramolecular activation clusters in T cells
    • Monks C.R., Freiberg B.A., Kupfer H., Sciaky N., Kupfer A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature. 395:1998;82-86.
    • (1998) Nature , vol.395 , pp. 82-86
    • Monks, C.R.1    Freiberg, B.A.2    Kupfer, H.3    Sciaky, N.4    Kupfer, A.5
  • 26
    • 0032568580 scopus 로고    scopus 로고
    • Visualizing the dynamics of T cell activation: Intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels
    • Wulfing C., Sjaastad M.D., Davis M.M. Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels. PNAS. 95:1998;6302-6307.
    • (1998) PNAS , vol.95 , pp. 6302-6307
    • Wulfing, C.1    Sjaastad, M.D.2    Davis, M.M.3
  • 27
    • 0032534057 scopus 로고    scopus 로고
    • LFA-1 interaction with ICAM-1 and ICAM-2 regulates Th2 cytokine production
    • Salomen B., Bluestone J.A. LFA-1 interaction with ICAM-1 and ICAM-2 regulates Th2 cytokine production. J Immunol. 161:1998;5138-5142.
    • (1998) J Immunol , vol.161 , pp. 5138-5142
    • Salomen, B.1    Bluestone, J.A.2
  • 29
  • 30
    • 0031895095 scopus 로고    scopus 로고
    • Requirement for p56(lck) tyrosine kinase activation in Th subset differentiation
    • Yamashita M., Hashimoto K., Kimura M., Kubo M., Tada T., Nakayama T. Requirement for p56(lck) tyrosine kinase activation in Th subset differentiation. Int Immunol. 10:1998;577-591.
    • (1998) Int Immunol , vol.10 , pp. 577-591
    • Yamashita, M.1    Hashimoto, K.2    Kimura, M.3    Kubo, M.4    Tada, T.5    Nakayama, T.6
  • 31
    • 0030457032 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase participates in p56(lck)/CD4-dependent down-regulation of LFA-1 mediated T cell adhesion
    • Mazerolles F., Barbat C., Hivroz C., Fischer A. Phosphatidylinositol 3-kinase participates in p56(lck)/CD4-dependent down-regulation of LFA-1 mediated T cell adhesion. J Immunol. 157:1996;4844-4854.
    • (1996) J Immunol , vol.157 , pp. 4844-4854
    • Mazerolles, F.1    Barbat, C.2    Hivroz, C.3    Fischer, A.4
  • 33
    • 0032521266 scopus 로고    scopus 로고
    • Inhibition of T cell activation by pharmacologic disruption of the MEK1/ERK MAP kinase or calcineurin signaling pathways results in differential modulation of cytokine production
    • Dumont F.J., Staruch M.J., Fischer P., Dasilva C., Ramon C. Inhibition of T cell activation by pharmacologic disruption of the MEK1/ERK MAP kinase or calcineurin signaling pathways results in differential modulation of cytokine production. J Immunol. 160:1998;2579-2589.
    • (1998) J Immunol , vol.160 , pp. 2579-2589
    • Dumont, F.J.1    Staruch, M.J.2    Fischer, P.3    Dasilva, C.4    Ramon, C.5
  • 37
    • 0029876629 scopus 로고    scopus 로고
    • STAT6 is required for mediating responses to IL4 and for the development of Th2 cells
    • Kaplan M.H., Schindler U., Smiley S.T., Grusby M.J. STAT6 is required for mediating responses to IL4 and for the development of Th2 cells. Immunity. 4:1996;313-319.
    • (1996) Immunity , vol.4 , pp. 313-319
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 38
    • 0030604714 scopus 로고    scopus 로고
    • The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin 4
    • Ho I-C, Hodge M.R., Rooney J.W., Glimcher L.H. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin 4. Cell. 85:1996;973-983.
    • (1996) Cell , vol.85 , pp. 973-983
    • Ho, I.-C.1    Hodge, M.R.2    Rooney, J.W.3    Glimcher, L.H.4
  • 39
    • 0032538985 scopus 로고    scopus 로고
    • C-maf promotes Th2 and attenuates Th1 differentiation by both IL-4 dependent and independent mechanisms
    • Ho I-C, Lo D., Glimcher L.H. c-maf promotes Th2 and attenuates Th1 differentiation by both IL-4 dependent and independent mechanisms. J Exp Med. 188:1998;1859-1866.
    • (1998) J Exp Med , vol.188 , pp. 1859-1866
    • Ho, I.-C.1    Lo, D.2    Glimcher, L.H.3
  • 40
    • 0030764961 scopus 로고    scopus 로고
    • Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin 5 gene
    • Zhang D.H., Cohn L., Ray P., Bottomly K., Ray A. Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin 5 gene. J Biol Chem. 272:1997;21597-21603.
    • (1997) J Biol Chem , vol.272 , pp. 21597-21603
    • Zhang, D.H.1    Cohn, L.2    Ray, P.3    Bottomly, K.4    Ray, A.5
  • 41
    • 0030810155 scopus 로고    scopus 로고
    • The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
    • Zheng W-P, Flavell R.A. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell. 89:1997;587-596.
    • (1997) Cell , vol.89 , pp. 587-596
    • Zheng, W.-P.1    Flavell, R.A.2
  • 42
    • 0344196985 scopus 로고    scopus 로고
    • Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation
    • Li B., Tournier C., Davis R.J., Flavell R.A. Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation. EMBO J. 18:1999;420-432.
    • (1999) EMBO J , vol.18 , pp. 420-432
    • Li, B.1    Tournier, C.2    Davis, R.J.3    Flavell, R.A.4
  • 43
    • 0031034051 scopus 로고    scopus 로고
    • +T helper 2 (Th2) cells but not in Th1 cells
    • +T helper 2 (Th2) cells but not in Th1 cells. Mol Cell Biol. 17:1997;1522-1534.
    • (1997) Mol Cell Biol , vol.17 , pp. 1522-1534
    • Rincon, M.1    Flavell, R.A.2
  • 46
    • 0032212631 scopus 로고    scopus 로고
    • Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development
    • Ranger A.M., Oukka M., Rengarajan J., Glimcher L.H. Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development. Immunity. 9:1998;627-635.
    • (1998) Immunity , vol.9 , pp. 627-635
    • Ranger, A.M.1    Oukka, M.2    Rengarajan, J.3    Glimcher, L.H.4
  • 47
    • 0032412441 scopus 로고    scopus 로고
    • Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation
    • Agarwal S., Rao A. Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation. Immunity. 9:1998;765-775.
    • (1998) Immunity , vol.9 , pp. 765-775
    • Agarwal, S.1    Rao, A.2


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