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Volumn 160, Issue 10, 1998, Pages 4841-4849

Partial TCR signals delivered by FcR-nonbinding anti-CD3 monoclonal antibodies differentially regulate individual Th subsets

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CD3; T LYMPHOCYTE RECEPTOR;

EID: 0032524957     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (92)

References (38)
  • 1
    • 0021816056 scopus 로고
    • A randomized clinical trial of OKT3 monoclonal antibody for acute rejection of cadaveric renal transplants
    • Ortho Multicenter Transplant Study Group. 1985. A randomized clinical trial of OKT3 monoclonal antibody for acute rejection of cadaveric renal transplants. N. Engl. J. Med 313:337.
    • (1985) N. Engl. J. Med , vol.313 , pp. 337
  • 2
    • 0022610836 scopus 로고
    • Fc receptors on monocytes cause OKT3-treated lymphocytes to internalize T3 and to secrete IL-2
    • Kan, E. A. R., S. D. Wright, K. Welte, and C. Y. Wang. 1986. Fc receptors on monocytes cause OKT3-treated lymphocytes to internalize T3 and to secrete IL-2. Cell. Immunol. 98:181.
    • (1986) Cell. Immunol. , vol.98 , pp. 181
    • Kan, E.A.R.1    Wright, S.D.2    Welte, K.3    Wang, C.Y.4
  • 5
    • 0029102761 scopus 로고
    • An anti-murine CD3 monoclonal antibody with a low affinity for Fcγ receptors suppresses transplantation responses while minimizing acute toxicity and immunogenicity
    • Alegre, M. L., J. Y. Tso, H. A. Sattar, J. Smith, F. Desalle, M. Cole, and J. A. Bluestone. 1995. An anti-murine CD3 monoclonal antibody with a low affinity for Fcγ receptors suppresses transplantation responses while minimizing acute toxicity and immunogenicity. J. Immunol. 155:1544.
    • (1995) J. Immunol. , vol.155 , pp. 1544
    • Alegre, M.L.1    Tso, J.Y.2    Sattar, H.A.3    Smith, J.4    Desalle, F.5    Cole, M.6    Bluestone, J.A.7
  • 6
    • 0027457925 scopus 로고
    • Multiple components of the T cell antigen receptor complex become tyrosine-phosphorylated upon activation
    • Qian, D., I. Griswold-Prenner, M. R. Rosner, and F. W. Fitch. 1993. Multiple components of the T cell antigen receptor complex become tyrosine-phosphorylated upon activation. J. Biol. Chem. 268:4488.
    • (1993) J. Biol. Chem. , vol.268 , pp. 4488
    • Qian, D.1    Griswold-Prenner, I.2    Rosner, M.R.3    Fitch, F.W.4
  • 7
    • 0028014460 scopus 로고
    • Signal transduction by lymphocyte antigen receptors
    • Weiss, A., and D. R. Littman. 1994. Signal transduction by lymphocyte antigen receptors. Cell 76:263.
    • (1994) Cell , vol.76 , pp. 263
    • Weiss, A.1    Littman, D.R.2
  • 8
    • 0030896612 scopus 로고    scopus 로고
    • Nonmitogenic anti-CD3 monoclonal antibodies deliver a partial T cell receptor signal and induce clonal anergy
    • Smith, J. A., J. Y. Tso, M. R. Clark, M. S. Cole, and J. A. Bluestone. 1997. Nonmitogenic anti-CD3 monoclonal antibodies deliver a partial T cell receptor signal and induce clonal anergy. J. Exp. Med. 185:1413.
    • (1997) J. Exp. Med. , vol.185 , pp. 1413
    • Smith, J.A.1    Tso, J.Y.2    Clark, M.R.3    Cole, M.S.4    Bluestone, J.A.5
  • 9
    • 0027298445 scopus 로고
    • Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells
    • Sloan-Lancaster, J., B. D. Evavold, and P. M. Allen. 1993. Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells. Nature 363:156.
    • (1993) Nature , vol.363 , pp. 156
    • Sloan-Lancaster, J.1    Evavold, B.D.2    Allen, P.M.3
  • 10
    • 0027967385 scopus 로고
    • Partial T cell signaling: Altered phospho-zeta and lack of ZAP70 recruitment in APL-induced T cell anergy
    • Sloan-Lancaster, J., A. S. Shaw, J. B. Rothbard, and P. M. Allen. 1994. Partial T cell signaling: altered phospho-zeta and lack of ZAP70 recruitment in APL-induced T cell anergy. Cell 79:913.
    • (1994) Cell , vol.79 , pp. 913
    • Sloan-Lancaster, J.1    Shaw, A.S.2    Rothbard, J.B.3    Allen, P.M.4
  • 11
    • 0028902752 scopus 로고
    • Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists
    • Madrenas, J., R. L. Wange, J. L. Wang, N. Isakov, L. E. Samelson, and R. N. Germain. 1995. Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists. Science 267:515.
    • (1995) Science , vol.267 , pp. 515
    • Madrenas, J.1    Wange, R.L.2    Wang, J.L.3    Isakov, N.4    Samelson, L.E.5    Germain, R.N.6
  • 12
    • 0031569177 scopus 로고    scopus 로고
    • CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice
    • Chatenoud, L., J. Primo, and J.-F. Bach. 1997. CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice. J. Immunol. 158:2947.
    • (1997) J. Immunol. , vol.158 , pp. 2947
    • Chatenoud, L.1    Primo, J.2    Bach, J.-F.3
  • 13
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas, A. K., K. M. Murphy, and A. Sher. 1996. Functional diversity of helper T lymphocytes. Nature 383:787.
    • (1996) Nature , vol.383 , pp. 787
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 15
    • 0030472449 scopus 로고    scopus 로고
    • Manipulation of the Th1/Th2 balance in autoimmune disease
    • Nicholson, L. B., and V. K. Kuchroo. 1996. Manipulation of the Th1/Th2 balance in autoimmune disease. Curr. Opin. Immunol. 8:837.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 837
    • Nicholson, L.B.1    Kuchroo, V.K.2
  • 17
    • 0028967385 scopus 로고
    • Increased expression of IL-4 and IL-10 and decreased expression of IL-2 and Interferon-gamma in long-surviving mouse heart allografts after brief CD4-monoclonal antibody therapy
    • Mottram, P. L., W. R. Man, L. J. Purcell, I. F. McKenzie, and W. W. Hancock. 1995. Increased expression of IL-4 and IL-10 and decreased expression of IL-2 and Interferon-gamma in long-surviving mouse heart allografts after brief CD4-monoclonal antibody therapy. Transplantation 59:559.
    • (1995) Transplantation , vol.59 , pp. 559
    • Mottram, P.L.1    Man, W.R.2    Purcell, L.J.3    McKenzie, I.F.4    Hancock, W.W.5
  • 18
    • 0028058940 scopus 로고
    • Induction of T helper cell hyporesponsiveness in an experimental model of autoimmunity by using nonmitogenic anti-CD3 monoclonal antibody
    • Hughes, C., J. A. Wolos, E. H. Giannini, and R. Hirsch. 1994. Induction of T helper cell hyporesponsiveness in an experimental model of autoimmunity by using nonmitogenic anti-CD3 monoclonal antibody. J. Immunol. 153:3319.
    • (1994) J. Immunol. , vol.153 , pp. 3319
    • Hughes, C.1    Wolos, J.A.2    Giannini, E.H.3    Hirsch, R.4
  • 19
    • 0028181231 scopus 로고
    • IL-4 treatment of small splenic B cells induces costimulatory molecules B7-1 and B7-2
    • Stack, R. M., D. J. Lenschow, G. S. Gray, J. A. Bluestone, and F. W. Fitch. 1994. IL-4 treatment of small splenic B cells induces costimulatory molecules B7-1 and B7-2. J. Immunol. 152:5723.
    • (1994) J. Immunol. , vol.152 , pp. 5723
    • Stack, R.M.1    Lenschow, D.J.2    Gray, G.S.3    Bluestone, J.A.4    Fitch, F.W.5
  • 20
    • 0023266396 scopus 로고
    • Stimulation of normal inducer T cell clones with antigen presented by purified Ia molecules in planar lipid membranes: Specific induction of a long-lived state of proliferate e nonresponsiveness
    • Quill, H., and R. H. Schwartz. 1987. Stimulation of normal inducer T cell clones with antigen presented by purified Ia molecules in planar lipid membranes: specific induction of a long-lived state of proliferate e nonresponsiveness. J. Immunol. 138:3704.
    • (1987) J. Immunol. , vol.138 , pp. 3704
    • Quill, H.1    Schwartz, R.H.2
  • 21
    • 0028167459 scopus 로고
    • Anergy of TH0 helper T lymphocytes induces downregulation of TH1 characteristics and a transition to a TH2-like phenotype
    • Gajewski, T. F., D. W. Lancki, R. Stack, and F. W. Fitch. 1994. Anergy of TH0 helper T lymphocytes induces downregulation of TH1 characteristics and a transition to a TH2-like phenotype. J. Exp. Med. 179:481.
    • (1994) J. Exp. Med. , vol.179 , pp. 481
    • Gajewski, T.F.1    Lancki, D.W.2    Stack, R.3    Fitch, F.W.4
  • 22
    • 0029874657 scopus 로고    scopus 로고
    • T cell antigen receptor signal transduction pathways
    • Cantrell, D. 1996. T cell antigen receptor signal transduction pathways. Annu. Rev. Immunol. 14:259.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 259
    • Cantrell, D.1
  • 24
    • 0028300431 scopus 로고
    • NF-ATp: A transcription factor required for the coordinate induction of several cytokine genes
    • Rao, A. 1994. NF-ATp: a transcription factor required for the coordinate induction of several cytokine genes. Immunol. Today 15:274.
    • (1994) Immunol. Today , vol.15 , pp. 274
    • Rao, A.1
  • 25
    • 0029952074 scopus 로고    scopus 로고
    • Selective activation of the calcium signaling pathway by altered peptide ligands
    • Sloan-Lancaster, J., T. H. Steinberg, and P. M. Allen. 1996. Selective activation of the calcium signaling pathway by altered peptide ligands. J. Exp. Med. 184:1525.
    • (1996) J. Exp. Med. , vol.184 , pp. 1525
    • Sloan-Lancaster, J.1    Steinberg, T.H.2    Allen, P.M.3
  • 26
    • 0026316280 scopus 로고
    • Clonal anergy blocks the response to IL-4, as well as the production of IL-2, in dual-producing T helper cell clones
    • Mueller, D. L., L. Chiodetti, P. A. Bacon, and R. H. Schwartz. 1991. Clonal anergy blocks the response to IL-4, as well as the production of IL-2, in dual-producing T helper cell clones. J. Immunol. 147:4118.
    • (1991) J. Immunol. , vol.147 , pp. 4118
    • Mueller, D.L.1    Chiodetti, L.2    Bacon, P.A.3    Schwartz, R.H.4
  • 27
    • 0031048822 scopus 로고    scopus 로고
    • The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands
    • Madrenas, J., L. A. Chau, J. Smith, J. A. Bluestone, and R. N. Germain. 1997. The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands. J. Exp. Med. 185:219.
    • (1997) J. Exp. Med. , vol.185 , pp. 219
    • Madrenas, J.1    Chau, L.A.2    Smith, J.3    Bluestone, J.A.4    Germain, R.N.5
  • 29
    • 0029008237 scopus 로고
    • Characterization of the constitutive and inducible components of a T cell IL-4 activation-responsive element
    • Tara, D., D. L. Weiss, and M. A. Brown. 1995. Characterization of the constitutive and inducible components of a T cell IL-4 activation-responsive element. J. Immunol. 154:4592.
    • (1995) J. Immunol. , vol.154 , pp. 4592
    • Tara, D.1    Weiss, D.L.2    Brown, M.A.3
  • 32
    • 0027433501 scopus 로고
    • Difference in signal transduction pathway for IL-2 and IL-4 production in T helper 1 and T helper 2 cell clones in response to anti-CD3
    • Tamura, T., T. Yanagida, and H. Nariuchi. 1993. Difference in signal transduction pathway for IL-2 and IL-4 production in T helper 1 and T helper 2 cell clones in response to anti-CD3. J. Immunol. 151:6051.
    • (1993) J. Immunol. , vol.151 , pp. 6051
    • Tamura, T.1    Yanagida, T.2    Nariuchi, H.3
  • 33
    • 0028157768 scopus 로고
    • A common factor regulates both Th1- And Th2-specific cytokine gene expression
    • Rooney, J. W., M. R. Hodge, P. G. McCaffrey, A. Rao, and L. H. Glimcher. 1994. A common factor regulates both Th1- and Th2-specific cytokine gene expression. EMBO J. 13:625.
    • (1994) EMBO J. , vol.13 , pp. 625
    • Rooney, J.W.1    Hodge, M.R.2    McCaffrey, P.G.3    Rao, A.4    Glimcher, L.H.5
  • 34
    • 0029030775 scopus 로고
    • Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene
    • Rooney, J. W., T. Hoey, and L. H. Glimcher. 1995. Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene. Immunity 2:473.
    • (1995) Immunity , vol.2 , pp. 473
    • Rooney, J.W.1    Hoey, T.2    Glimcher, L.H.3
  • 35
    • 0030604714 scopus 로고    scopus 로고
    • The protooncogene c-maf is responsible for tissue-specific expression of interleukin-4
    • Ho, I.-C., M. R. Hodge, J. W. Rooney, and L. H. Glimcher. 1996. The protooncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell 85:973.
    • (1996) Cell , vol.85 , pp. 973
    • Ho, I.-C.1    Hodge, M.R.2    Rooney, J.W.3    Glimcher, L.H.4
  • 36
    • 0030587190 scopus 로고    scopus 로고
    • Induction of Th2 cytokines and control of collagen-induced arthritis by nondepleting anti-CD4 Abs
    • Chu, C. Q., and M. Londei. 1996. Induction of Th2 cytokines and control of collagen-induced arthritis by nondepleting anti-CD4 Abs. J. Immunol. 157:2685.
    • (1996) J. Immunol. , vol.157 , pp. 2685
    • Chu, C.Q.1    Londei, M.2
  • 37
    • 0030797568 scopus 로고    scopus 로고
    • A T cell receptor antagonist peptide induces T cells that mediate bystander suppression and prevent autoimmune encephalomyelitis induced with multiple myelin antigens
    • Nicholson, L. B., A. Muraza, B. P. Hafler, A. Sette, and V. K. Kuchroo. 1997. A T cell receptor antagonist peptide induces T cells that mediate bystander suppression and prevent autoimmune encephalomyelitis induced with multiple myelin antigens. Proc. Natl. Acad. Sci. USA 94:9279.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9279
    • Nicholson, L.B.1    Muraza, A.2    Hafler, B.P.3    Sette, A.4    Kuchroo, V.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.