Impaired Th2 subset development in the absence of CD4

Immunity

Volumn 6, Issue 5, 1997, Pages 559-569

  Fowell, Deborah J ^a   Magram, Jeanne ^c   Turck, Christoph W ^a,b   Killeen, Nigel ^a   Locksley, Richard M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HOFFMANN LA ROCHE INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; CONTROLLED STUDY; DEVELOPMENT; FEMALE; HELPER CELL; LYMPHOCYTE DIFFERENTIATION; MOUSE; NIPPOSTRONGYLUS BRASILIENSIS; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 0030917080     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80344-1     Document Type: Article

References (68)

1. Abbas, A.K., Murphy, K.M., and Sher, A. (1996). Functional diversity of helper T lymphocytes. Nature 383, 787-793.
2. + thymocytes selected by MHC class I molecules. Science 263, 1774-1778.
3. Berens, R.L., and Marr, J.J. (1978). An easily prepared defined medium for cultivation of Leishmania donovani promastigotes. J. Parasitol. 64, 160-163.
4. + T cells are not essential for T helper cell 2 immune responses. J. Exp. Med. 184, 1295-1304.
5. Bruno, L, Fehling, H.J., and von Boehmer, H. (1996). The αβ T cell receptor can replace the γδ receptor in the development of γδ lineage cells. Immunity 5, 343-352.
6. Cammarota, G., Scheirle, A., Takacs, B., Doran, D.M., Knorr, R., Bannwarth, W., Guardiola, J., and Sinigaglia, F. (1992). Identification of a CD4 binding site on the β2 domain of HLA-DR molecules. Nature 356, 799-801.
7. Capone, M., Curnow, J., Bouvier, G., Ferrier, P., and Horvat, B. (1995). T cell development in TCR-αβ transgenic mice. Analysis using V(D)J recombination substrates. J. Immunol. 154, 5165-5172.
8. + precursors. Science 242, 1174-1176.
9. Chan, A.C., van Oers, N.S.C., Tran, A., Turka, L., Law, C.-L., Ryan, J.C., Clark, E.A., and Weiss, A. (1994). Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling. J. Immunol. 152, 4758-4766.
10. + T cells. J. Exp. Med. 182, 1591-1596.
11. Doyle, C., and Strominger, J.L. (1987). Interaction between CD4 and class II MHC molecules mediates cell adhesion. Nature 330, 256-259.
12. Fleury, S., Lamarre, D., Meloche, S., Ryu, S.-E., Cantin, C., Hendrickson, W.A., and Sekaly, R.-P. (1991). Mutational analysis of the interaction between CD4 and class II MHC: class II antigens contact CD4 on a surface opposite the gp120-binding site. Cell 66, 1037-1049.
13. Gajewski, T.F., Pinnas, M., Wong, T., and Fitch, F.W. (1991). Murine Th1 and Th2 clones proliferate optimally in response to distinct antigen-presenting cell populations. J. Immunol. 146, 1750-1758.
14. Garboczi, D.N., Ghosh, P., Utz, U., Fan, Q.R., Biddison, W.E., and Wiley, D.C. (1996). Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature 384, 134-141.
15. Garcia, K.C., Degano, M., Stanfield, R.L., Brunmark, A., Jackson, M.R., Peterson, P.A., Teyton, L., and Wilson, I.A. (1996). An αβ T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. Science 274, 209-219.
16. Garcia, K.C., Scott, C.A., Brunmark, A., Carbone, F.R., Peterson, P.A., Wilson, I.A., and Teyton, L. (1996). CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes. Nature 384, 577-581.
17. Germain, R.N. (1993). Seeing double. Curr. Biol. 3, 586-589.
18. Gorham, J.D., Guler, M.L., Steen, R.G., Mackey, A.A., Daly, M.J., Frederick, K., Dietrich, W.F., and Murphy, K.M. (1996). Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses. Proc. Natl. Acad. Sci. USA 93, 12467-12472.
19. Guery, J.-C., Galbiati, F., Smiroldo, S., and Adorini, L. (1996). Selective development of T helper (Th)2 cells induced by continuous administration of low dose soluble proteins to normal and β2-microglobulin-deficient BALB/c mice. J. Exp. Med. 183, 485-497.
20. + T helper cell phenotype development in aT cell receptor-αβ transgenic model. J. Exp. Med. 182, 1579-1584.
21. Huang, B., Yachou, A., Fleury, S, Hendrickson, W.A., and Sekaly, R.-P. (1997). Analysis of the contact sites on the CD4 molecule with class II MHC molecule: co-ligand versus co-receptor function. J. Immunol. 158, 216-225.
22. Imai, T., Kakizaki, M., Nishimura, M., and Yoshie, O. (1995). Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82. J. Immunol. 155, 1229-1239.
23. Jameson, S.C., Hogquist, K.A., and Bevan, M.J. (1994). Specificity and flexibility in thymic selection. Nature 369, 750-752.
24. Kearney, E.R., Pape, K.A., Loh, D.Y., and Jenkins, M.K. (1994). Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1, 327-339.
25. Killeen, N., Stuart, S.G., and Littman, D.R. (1992). Development and function of T cells in mice with a disrupted CD2 gene. EMBO J. 11, 4329-4336.
26. Killeen, N., and Littman, D.R. (1993). Helper T-cell development in the absence of CD4-p56lck association. Nature 364, 729-732.
27. Killeen, N., Sawada, S., and Littman, D.R. (1993). Regulated expression of human CD4 rescues helper T cell development in mice lacking expression of endogenous CD4. EMBO J. 12, 1547-1553.
28. + thymocytes. Nature 333, 742-746.
29. Konig, R., Huang, L.Y., and Germain, R.N. (1992). MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8. Nature 356, 796-798.
30. Konig, R., Shen, X., and Germain, R.N. (1995). Involvement of both major histocompatibility complex class II α and β chains in CD4 function indicates a role for ordered oligomerization in T cell activation. J. Exp. Med. 182, 779-787.
31. Kumar, V., Bhardwaj, V., Soares, L., Alexander, J., Sette, A., and Sercarz, E. (1995). Major histocompatibility complex binding affinity of an antigenic determinant is crucial for the differential secretion of interleukin 4/5 or interferon γ by T cells. Proc. Natl. Acad. Sci. USA 92, 9510-9514.
32. +, double-positive stage. J. Exp. Med. 184, 1619-1630.
33. Locksley, R.M., Reiner, S.L., Hatam, F., Liftman, D.R., and Killeen, N. (1993). Helper T cells without CD4: control of leishmaniasis in CD4-deficient mice. Science 261, 1448-1451.
34. Luescher, I.F., Vivier, E., Layer, A., Mahiou, J., Godeau, F., Mallissen, B., and Romero, P. (1995). CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes. Nature 373, 353-356.
35. Magram, J., Connaughton, S.E., Warrier, R.R., Carvajal, D.M., Wu, C.-Y., Ferrante, J., Stewart, C., Sarmiento, U., Faherty, D.A., and Gately, M.K. (1996). IL-12-deficient mice are defective in IFNγ production and type 1 cytokine responses. Immunity 4, 471-481.
36. Mallick-Wood, C.A., Pao, W., Cheng, A.M., Lewis, J.M., Kulkarni, S., Bolen, J.B., Rowley, B., Tigelaar, R.E., Pawson, T., and Hayday, A.C. (1996). Disruption of epithelial γδ T cell repertoires by mutation of the Syk tyrosine kinase. Proc. Natl. Acad. Sci. USA 93, 9704-9709.
37. Mattner, F., Magram, J., Ferrante, J., Launois, P., Di Padova, K., Behin, R., Gately, M.K., Louis, J.A., and Alber, G. (1996). Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur. J. Immunol. 26, 1553-1559.
38. Moebius, U., Pallai, P., Harrison, S.C., and Reinherz, E.L. (1993). Delineation of an extended surface contact area on human CD4 involved in class II major histocompatibility complex binding. Proc. Natl. Acad. Sci. USA 90, 8259-8263.
39. Mombaerts, P., Iacomini, J., Johnson, R.S., Herrup, K., Tonegawa, S., and Papaioannou, V.E. (1992). RAG-1-deficient mice have no mature B and T lymphocytes. Cell 68, 869-877.
40. Mougneau, E., Altare, F., Wakil, A.E., Zheng, S., Coppola, T., Wang, Z.-E., Waldmann, R., Locksley, R.M., and Glaichenhaus, N. (1995). Expression cloning of a protective Leishmania antigen. Science 268, 563-566.
41. lo thymocytes in vivo. Science 250, 1720-1723.
42. + T cell subset activation. J. Exp. Med. 170, 2135-2140.
43. Ohno, H., Ono, S., Hirayama, N., Shimada, S., and Saito, T. (1994). Preferential usage of the Fc receptor γ chain in the T cell antigen receptor complex by γ/δ T cells localized in epithelia. J. Exp. Med. 179, 365-369.
44. Pfeiffer, C., Stein, J., Southwood, S., Ketelaar, H., Sette, A., and Bottomly, K. (1995). Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo. J. Exp. Med. 181, 1569-1574.
45. Philpott, K.L., Viney, J.L., Kay, G., Rastan, S., Gardiner, E.M., Chae, S., Hayday, A.C., and Owen, M.J. (1992). Lymphoid development in mice congenitally lacking T cell receptor αβ-expressing cells. Science 256, 1448-1452.
46. Qian, D., Sperling, A., Lancki, D.W., Tatsumi, Y., Barrett, T.A., Bluestone, J.A., and Fitch, F.W. (1993). The γ chain of the high-affinity receptor for IgE is a major functional subunit of the T-cell antigen receptor complex in γδ T lymphocytes. Proc. Natl. Acad. Sci. USA 90, 11875-11879.
47. + T cells but markedly decreased helper cell activity in mice lacking CD4. Nature 353, 180-184.
48. Rahemtulla, A., Kundig, T.M., Narendran, A., Bachmann, M.F., Julius, M., Paige, C.J., Ohashi, P.S., Zinkernagel, R.M., and Mak, T.W. (1994). Class II major histocompatibility complex-restricted T cell function in CD4-deficient mice. Eur. J. Immunol. 24, 2213-2218.
49. Reiner, S.L., Wang, Z.-E., Hatam, F., Scott, P., and Locksley, R.M. (1993). Th1 and Th2 cell antigen receptors in experimental leishmanias. Science 259, 1457-1460.
50. + T cells during initiation of infection. J. Exp. Med. 179, 447-456.
51. Reiner, S.L., and Locksley, R.M. (1995). The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13, 151-177.
52. Sawada, S., Scarborough, J.D., Killeen, N., and Littman, D.R. (1994). A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development. Cell 77, 917-929.
53. + T cells. Annu. Rev. Immunol. 12, 635-673.
54. Schountz, T., Kasselman, J.P., Martinson, F.A., Brown, L., and Murray, J.S. (1996). MHC genotype controls the capacity of ligand density to switch T helper (Th)-1/Th-2 priming in vivo. J. Immunol. 157, 3893-3901.
55. Scott, P., Caspar, P., and Sher, A. (1990). Protection against Leishmania major in BALB/c mice by adoptive transfer of a T cell clone recognizing a low molecular weight antigen released by promastigotes. J. Immunol. 144, 1075-1079.
56. Shaw, A.S., Amrein, K.E., Hammond, C., Stern, D.F., Sefton, B.M., and Rose, J.K. (1989). The lck tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain. Cell 59, 627-636.
57. + T lymphocytes in vitro and in vivo. J. Immunol. 157, 87-100.
58. Sherman, L.A., Hesse, S.V., Irwin, M.J., La Face, D., and Peterson, P. (1992). Selecting T cell receptors with high affinity for self-MHC by decreasing the contribution of CD8. Science 258, 815-818.
59. Shiue, L., Zoller, M.J., and Brugge, J.S. (1995). Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE. J. Biol. Chem. 270, 10498-10502.
60. Symer, D.E., Dintzis, R.Z., Diamond, D.J., and Dintzis, H.M. (1992). Inhibition or activation of human T cell receptor transfectants is controlled by defined, soluble antigen arrays. J. Exp. Med. 176, 1421-1430.
61. Thompson, C.B. (1995). Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation? Cell 81, 979-982.
62. Titus, R.G., Milon, G., Marchal, G., Vassalli, P., Cerottini, J.-C., and Louis, J.A. (1987). Involvement of specific Lyt-2+ T cells in the immunological control of experimentally induced cutaneous leishmaniasis. Eur. J. Immunol. 17, 1429-1433.
63. Urban, J.F., Madden, K.B., Svetic, A., Cheever, A., Trotta, P.P., Cause, W.C., Katona, I.M., and Finkelman, F.D. (1992). The importance of Th2 cytokines in protective immunity to nematodes. Immunol. Rev. 127, 205-220.
64. Urban, J.F., Maliszewski, C.R., Madden, K.B., Katona, I.M., and Finkelman, F.D. (1995). IL-4 treatment can cure established gastrointestinal nematode infections in immunocompetent and immunodeficient mice. J. Immunol. 154, 4675-4684.
65. Vignali, D.A.A., Carson, R.T., Chang, B., Mittle, R.S., and Strominger, J.L. (1996). The two membrane proximal domains of CD4 interact with the T cell receptor. J. Exp. Med. 183, 2097-2107.
66. Wilson, A., Pircher, H., Ohashi, P., and MacDonald, H.R. (1992). Analysis of immature (CD4-CD8-) thymic subsets in T-cell receptor αβ transgenic mice. Dev. Immunol. 2, 85-94.
67. Yoshimoto, T., and Paul, W.E. (1994). CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3. J. Exp. Med. 179, 1285-1295.
68. + T cells in a Th2 response and in immunoglobulin E production. Science 270, 1845-1847.