Inhibition of T cell activation by pharmacologic disruption of the MEK1/ERK MAP kinase or calcineurin signaling pathways results in differential modulation of cytokine production

Journal of Immunology

Volumn 160, Issue 6, 1998, Pages 2579-2589

  Dumont, Francis J ^a   Staruch, Mary Jo ^a   Fischer, Paul ^a   DaSilva, Carolyn ^a   Camacho, Ramon ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; TACROLIMUS; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL PROLIFERATION; CELL STIMULATION; CROSS LINKING; ENZYME ACTIVITY; ENZYME INHIBITION; GENE ACTIVATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SECOND MESSENGER; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANTIGENS, CD28; ANTIGENS, CD3; CALCINEURIN; CELLS, CULTURED; CYTOKINES; FLAVONOIDS; HUMANS; LYMPHOCYTE ACTIVATION; MAP KINASE KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; RNA, MESSENGER; T-LYMPHOCYTES; TACROLIMUS; TETRADECANOYLPHORBOL ACETATE;

EID: 0032521266     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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