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Volumn 8, Issue 1, 1998, Pages 125-134

Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 4; TRANSCRIPTION FACTOR;

EID: 0031933037     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80465-3     Document Type: Article
Times cited : (263)

References (44)
  • 1
    • 0030899131 scopus 로고    scopus 로고
    • Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction
    • Beals, C.R., Clipstone, N.A., Ho, S.N., and Crabtree, G.R. (1997). Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction. Genes Dev. 11, 824-834.
    • (1997) Genes Dev. , vol.11 , pp. 824-834
    • Beals, C.R.1    Clipstone, N.A.2    Ho, S.N.A.3    Crabtree, G.R.4
  • 3
    • 0027215522 scopus 로고
    • RAG-2-deficient blastocyst complementation: An assay of gene function in lymphocyte development
    • Chen, J., Lansford, R., Stewart, V., Young, F., and Alt, F.W. (1993). RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development. Proc. Natl. Acad. Sci. USA 90, 4528-4532.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4528-4532
    • Chen, J.1    Lansford, R.2    Stewart, V.3    Young, F.4    Alt, F.W.5
  • 4
    • 0028450096 scopus 로고
    • Induction of NF-AT in normal B lymphocytes by anti-immunoglobulin or CD40 ligand in conjunction with IL-4
    • Choi, M.S. K., Brines, R.D., Holman, M.J., and Klaus, G.G. B. (1994). Induction of NF-AT in normal B lymphocytes by anti-immunoglobulin or CD40 ligand in conjunction with IL-4. Immunogenetics 1, 179-187.
    • (1994) Immunogenetics , vol.1 , pp. 179-187
    • Choi, M.S.K.1    Brines, R.D.2    Holman, M.J.3    Klaus, G.G.B.4
  • 5
    • 0027714991 scopus 로고
    • Multiple closely-linked NFAT/ octamer and HMG i (Y) binding sites are part of the interleukin-4 promoter
    • Chuvpilo, S., Schomberg, C., Gerwig, R., Heinfling, A., Reeves, R., Grummt, F., and Serfling, E. (1993). Multiple closely-linked NFAT/ octamer and HMG I (Y) binding sites are part of the interleukin-4 promoter. Nucleic Acid Res. 21, 5694-5704.
    • (1993) Nucleic Acid Res. , vol.21 , pp. 5694-5704
    • Chuvpilo, S.1    Schomberg, C.2    Gerwig, R.3    Heinfling, A.4    Reeves, R.5    Grummt, F.6    Serfling, E.7
  • 6
    • 0026643141 scopus 로고
    • Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation
    • Clipstone, N.A., and Crabtree, G.R. (1992). Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. Nature 357, 695-697.
    • (1992) Nature , vol.357 , pp. 695-697
    • Clipstone, N.A.1    Crabtree, G.R.2
  • 7
    • 0028930789 scopus 로고
    • Human granulocyte-macrophage colony-stimulating factor enhancer function is associated with cooperative interactions between AP-1 and NFATp/c
    • Cockerill, P.N., Bert, A.G., Jenkins, F., Ryan, G.R., Shannon, M.F., and Vadas, M.A. (1995). Human granulocyte-macrophage colony-stimulating factor enhancer function is associated with cooperative interactions between AP-1 and NFATp/c. Mol. Cell. Biol. 15, 2071-2079.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2071-2079
    • Cockerill, P.N.1    Bert, A.G.2    Jenkins, F.3    Ryan, G.R.4    Shannon, M.F.5    Vadas, M.A.6
  • 8
    • 0024548313 scopus 로고
    • Contingent genetic regulatory events in T lymphocyte activation
    • Crabtree, G. (1989). Contingent genetic regulatory events in T lymphocyte activation. Science 249, 355-360.
    • (1989) Science , vol.249 , pp. 355-360
    • Crabtree, G.1
  • 9
    • 0025807152 scopus 로고
    • Purified protein derivative of mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human t cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production
    • Del Prete, G.F., De Carli, M., Mastromauro, C., Biagniotti, R., Macchia, D., Falagiani, P., Ricci, M., and Romagnani, S. (1991). Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production. J. Clin. Invest. 88, 346-350.
    • (1991) J. Clin. Invest. , vol.88 , pp. 346-350
    • Del Prete, G.F.1    De Carli, M.2    Mastromauro, C.3    Biagniotti, R.4    Macchia, D.5    Falagiani, P.6    Ricci, M.7    Romagnani, S.8
  • 11
    • 0023932598 scopus 로고
    • Characterization of antigen receptor response elements within the interleukin-2 enhancer
    • Durand, D., Shaw, J., Bush, M., Replogle, R., Belagaje, R., and Crabtree, G. (1988). Characterization of antigen receptor response elements within the interleukin-2 enhancer. Mol. Cell. Biol. 8, 1715-1724.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 1715-1724
    • Durand, D.1    Shaw, J.2    Bush, M.3    Replogle, R.4    Belagaje, R.5    Crabtree, G.6
  • 12
    • 0024833664 scopus 로고
    • Cyclosporin a specifically inhibits function of nuclear proteins involved in T cell activation
    • Emmel, E.A., Verweij, C.L., Durand, D.B., Higgins, K.M., Lacy, E., and Crabtree, G.R. (1989). Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation. Science 246, 1617-1620.
    • (1989) Science , vol.246 , pp. 1617-1620
    • Emmel, E.A.1    Verweij, C.L.2    Durand, D.B.3    Higgins, K.M.4    Lacy, E.5    Crabtree, G.R.6
  • 13
    • 0025871394 scopus 로고
    • Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin a
    • Flanagan, W.M., Corthesy, B., Bram, R.J., and Crabtree, G.R. (1991). Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. Nature 352, 803-807.
    • (1991) Nature , vol.352 , pp. 803-807
    • Flanagan, W.M.1    Corthesy, B.2    Bram, R.J.3    Crabtree, G.R.4
  • 14
  • 15
    • 0027326457 scopus 로고
    • Identification of a novel cyclosporin-sensitive element in the human tumor necrosis factor α gene promoter
    • Goldfeld, A.E., McCaffrey, P.G., Strominger, J.L., and Rao, A. (1993). Identification of a novel cyclosporin-sensitive element in the human tumor necrosis factor α gene promoter. J. Exp. Med. 178, 1365-1379.
    • (1993) J. Exp. Med. , vol.178 , pp. 1365-1379
    • Goldfeld, A.E.1    McCaffrey, P.G.2    Strominger, J.L.3    Rao, A.4
  • 16
    • 0030294284 scopus 로고    scopus 로고
    • High mobility group protein I(Y) is required for function and for c-Rel binding to CD28 response elements within the GM-CSF and IL-2 promoters
    • Himes, S.R., Coles, L.S., Reeves, R., and Shannon, M.F. (1996). High mobility group protein I(Y) is required for function and for c-Rel binding to CD28 response elements within the GM-CSF and IL-2 promoters. Immunity 5, 479-489.
    • (1996) Immunity , vol.5 , pp. 479-489
    • Himes, S.R.1    Coles, L.S.2    Reeves, R.3    Shannon, M.F.4
  • 18
    • 0029053852 scopus 로고
    • Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins
    • Hoey, T., Sun, Y-L., Williamson, K., and Xu, X. (1995). Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins. Immunity 2, 461-472.
    • (1995) Immunity , vol.2 , pp. 461-472
    • Hoey, T.1    Sun, Y.-L.2    Williamson, K.3    Xu, X.4
  • 19
    • 0026596383 scopus 로고
    • Nuclear factor of activated T cells contains Fos and Jun
    • Jain, J., McCaffrey, P.G., Valge-Archer, V.E., and Rao, A. (1992). Nuclear factor of activated T cells contains Fos and Jun. Nature 356, 801-804.
    • (1992) Nature , vol.356 , pp. 801-804
    • Jain, J.1    McCaffrey, P.G.2    Valge-Archer, V.E.3    Rao, A.4
  • 20
    • 0027491776 scopus 로고
    • The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun
    • Jain, J., McCaffrey, P.G., Miner, Z., Kerppola, T.K., Lambert, J.N., Verdine, G.L., Curran, T., and Rao, A. (1993). The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. Nature 365, 352-355.
    • (1993) Nature , vol.365 , pp. 352-355
    • Jain, J.1    McCaffrey, P.G.2    Miner, Z.3    Kerppola, T.K.4    Lambert, J.N.5    Verdine, G.L.6    Curran, T.7    Rao, A.8
  • 21
    • 0029150389 scopus 로고
    • Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoural immunity, and interleukin-2 expression
    • Köntgen, F., Grumont, R.J., Strasser, A., Metcalf, D., Li, R., Tarlinton, D., and Gerondakis, S. (1995). Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoural immunity, and interleukin-2 expression. Genes Dev. 9, 1965-1977.
    • (1995) Genes Dev. , vol.9 , pp. 1965-1977
    • Köntgen, F.1    Grumont, R.J.2    Strasser, A.3    Metcalf, D.4    Li, R.5    Tarlinton, D.6    Gerondakis, S.7
  • 22
    • 0028180103 scopus 로고
    • 2+/calmodulin-activated, phosphoprotein phosphatase calcineurin is sufficient for positive transcriptional regulation of the mouse IL-4 gene
    • 2+/calmodulin-activated, phosphoprotein phosphatase calcineurin is sufficient for positive transcriptional regulation of the mouse IL-4 gene. Int. Immunol. 6, 179-188.
    • (1994) Int. Immunol. , vol.6 , pp. 179-188
    • Kubo, M.1    Kincaid, R.L.2    Webb, D.R.3    Ransom, J.T.4
  • 23
    • 0030949834 scopus 로고    scopus 로고
    • Expression of NFAT-family proteins in normal human T cells
    • Lyakh, L., Ghosh, P., and Rice, N.R. (1997). Expression of NFAT-family proteins in normal human T cells. Mol. Cell. Biol. 17, 2475-2484.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2475-2484
    • Lyakh, L.1    Ghosh, P.2    Rice, N.R.3
  • 24
    • 0027156770 scopus 로고
    • B lymphocyte development and activation independent of MHC class II expression
    • Markowitz, J.S., Rogers, P.R., Grusby, M.J., Parker, D.C., and Glimcher, L.H. (1993). B lymphocyte development and activation independent of MHC class II expression. J. Immunol. 150, 1223-1233.
    • (1993) J. Immunol. , vol.150 , pp. 1223-1233
    • Markowitz, J.S.1    Rogers, P.R.2    Grusby, M.J.3    Parker, D.C.4    Glimcher, L.H.5
  • 25
    • 0027488631 scopus 로고
    • The granulocyte-macrophage colony-stimulating factor promoter cis-acting element CLE0 mediates induction signals in T cells and is recognized by factors related to AP1 and NFAT
    • Masuda, E.S., Tokumitsu, H., Tsuboi, A., Shlomai, J., Hung, P., Arai, K.-i., and Arai, N. (1993). The granulocyte-macrophage colony-stimulating factor promoter cis-acting element CLE0 mediates induction signals in T cells and is recognized by factors related to AP1 and NFAT. Mol. Cell. Biol. 13, 7399-7407.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7399-7407
    • Masuda, E.S.1    Tokumitsu, H.2    Tsuboi, A.3    Shlomai, J.4    Hung, P.5    Arai, K.-I.6    Arai, N.7
  • 26
    • 0028930843 scopus 로고
    • NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus
    • Masuda, E.S., Naito, Y., Tokumitsu, H., Campbell, D., Saito, F., Hannum, C., Arai, K.-i., and Arai, N. (1995). NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus. Mol. Cell. Biol. 15, 2697-2706.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2697-2706
    • Masuda, E.S.1    Naito, Y.2    Tokumitsu, H.3    Campbell, D.4    Saito, F.5    Hannum, C.6    Arai, K.-I.7    Arai, N.8
  • 28
    • 0025931765 scopus 로고
    • Characterization of the mouse granulocyte-macrophage colony-stimulating factor (GM-CSF) gene promoter: Nuclear factors that interact with an element shared by three lymphokine genes-those for GM-CSF, interleukin-4 (IL-4), and IL-5
    • Miyatake, S., Shlomai, J., Arai, K., and Arai, N. (1991). Characterization of the mouse granulocyte-macrophage colony-stimulating factor (GM-CSF) gene promoter: nuclear factors that interact with an element shared by three lymphokine genes-those for GM-CSF, interleukin-4 (IL-4), and IL-5. Mol. Cell. Biol. 11, 5894-5901.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5894-5901
    • Miyatake, S.1    Shlomai, J.2    Arai, K.3    Arai, N.4
  • 30
    • 0029786684 scopus 로고    scopus 로고
    • Characterization of a new isoform of the NFAT (nuclear factor of activated T cells) gene family member NFATc
    • Park, J., Takeuchi, A., and Sharma, S. (1996). Characterization of a new isoform of the NFAT (nuclear factor of activated T cells) gene family member NFATc. J. Biol. Chem. 271, 20914-20921.
    • (1996) J. Biol. Chem. , vol.271 , pp. 20914-20921
    • Park, J.1    Takeuchi, A.2    Sharma, S.3
  • 32
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NFAT family: Regulation and function
    • Rao, A., Luo, C., and Hogan, P.G. (1997). Transcription factors of the NFAT family: regulation and function. Annu. Rev. Immunol. 15, 707-747.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 707-747
    • Rao, A.1    Luo, C.A.2    Hogan, P.G.3
  • 33
    • 0028157768 scopus 로고
    • A common factor regulates both Th1- and Th2-specific cytokine gene expression
    • Rooney, J.W., Hodge, M.R., McCaffrey, P.G., Rao, A., and Glimcher, L.H. (1994). A common factor regulates both Th1- and Th2-specific cytokine gene expression. EMBO J. 13, 625-633.
    • (1994) EMBO J. , vol.13 , pp. 625-633
    • Rooney, J.W.1    Hodge, M.R.2    McCaffrey, P.G.3    Rao, A.A.4    Glimcher, L.H.5
  • 34
    • 0029030775 scopus 로고
    • Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene
    • Rooney, J.W., Hoey, T., and Glimcher, L.H. (1995a). Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene. Immunity 2, 545-553.
    • (1995) Immunity , vol.2 , pp. 545-553
    • Rooney, J.W.1    Hoey, T.2    Glimcher, L.H.3
  • 35
    • 0028857929 scopus 로고
    • Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation
    • Rooney, J., Sun, Y-L., Glimcher, L.H., and Hoey, T. (1995b). Novel NFAT sites that mediate activation of the interleukin-2 promoter in response to T-cell receptor stimulation. Mol. Cell. Biol. 15, 6299-6310.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6299-6310
    • Rooney, J.1    Sun, Y.-L.2    Glimcher, L.H.3    Hoey, T.4
  • 36
    • 0023821516 scopus 로고
    • Identification of a putative regulator of early T cell activation genes
    • Shaw, J., Utz, P., Durand, D., Toole, J., Emmel, E., and Crabtree, G. (1988). Identification of a putative regulator of early T cell activation genes. Science 241, 202-205.
    • (1988) Science , vol.241 , pp. 202-205
    • Shaw, J.1    Utz, P.2    Durand, D.3    Toole, J.4    Emmel, E.5    Crabtree, G.6
  • 37
    • 0023197097 scopus 로고
    • Interferon-γ and B cell stimulatory factor-1 reciprocally regulate Ig isotype production
    • Snapper, C.M., and Paul, W.E. (1987). Interferon-γ and B cell stimulatory factor-1 reciprocally regulate Ig isotype production. Science 236, 944-947.
    • (1987) Science , vol.236 , pp. 944-947
    • Snapper, C.M.1    Paul, W.E.2
  • 38
    • 0023933655 scopus 로고
    • Differential regulation of IgG1 and IgE synthesis by interleukin 4
    • Snapper, C.M., Finkelman, F.D., and Paul, W.E. (1988). Differential regulation of IgG1 and IgE synthesis by interleukin 4. J. Exp. Med. 167, 183-196.
    • (1988) J. Exp. Med. , vol.167 , pp. 183-196
    • Snapper, C.M.1    Finkelman, F.D.2    Paul, W.E.3
  • 39
    • 0027305687 scopus 로고
    • Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: Roles for NF-Y and NF-ATc
    • Szabo, S.J., Gold, J.S., Murphy, T.L., and Murphy, K.M. (1993). Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: roles for NF-Y and NF-ATc. Mol. Cell. Biol. 13, 4793-4805.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4793-4805
    • Szabo, S.J.1    Gold, J.S.2    Murphy, T.L.3    Murphy, K.M.4
  • 40
    • 0031571716 scopus 로고    scopus 로고
    • Redundant expression but selective utilization of nuclear factor of activated T cells family members
    • Timmerman, L.A., Healy, J.I., Ho, S.N., Chen, L., Goodnow, C.C., and Crabtree, G.R. (1997). Redundant expression but selective utilization of nuclear factor of activated T cells family members. J. Immunol. 159, 2735-2740.
    • (1997) J. Immunol. , vol.159 , pp. 2735-2740
    • Timmerman, L.A.1    Healy, J.I.2    Ho, S.N.3    Chen, L.4    Goodnow, C.C.5    Crabtree, G.R.6
  • 42
    • 0025127909 scopus 로고
    • Cell type specificity and activation requirements for NF-AT-1 transcriptional activity determined by a new method using transgenic mice to assay transcriptional activity of an individual nuclear factor
    • Verweij, C.L., Guidos, C., and Crabtree, G.R. (1990). Cell type specificity and activation requirements for NF-AT-1 transcriptional activity determined by a new method using transgenic mice to assay transcriptional activity of an individual nuclear factor. J. Biol. Chem. 265, 15788-15795.
    • (1990) J. Biol. Chem. , vol.265 , pp. 15788-15795
    • Verweij, C.L.1    Guidos, C.2    Crabtree, G.R.3
  • 43
    • 0030907779 scopus 로고    scopus 로고
    • C-rel is a target of pentoxifylline-mediated inhibition of T lymphocyte activation
    • Wang, W., Tam, W.F., Hughes, C.C. W., Rath, S., and Sen, R. (1997). c-Rel is a target of pentoxifylline-mediated inhibition of T lymphocyte activation. Immunity 6, 165-174.
    • (1997) Immunity , vol.6 , pp. 165-174
    • Wang, W.1    Tam, W.F.2    Hughes, C.C.W.3    Rath, S.A.4    Sen, R.5


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