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Monoallelic expression of the interluekin-2 locus
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+ T cells, in which the two IL-2 alleles can be distinguished by a polymorphism, transcribe either the maternal or paternal genes. This locus also replicates asynchronously.
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+ T cells, in which the two IL-2 alleles can be distinguished by a polymorphism, transcribe either the maternal or paternal genes. This locus also replicates asynchronously.
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(1998)
Science
, vol.279
, pp. 2118-2121
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Hollander, G.A.1
Zuklys, S.2
Morel, C.3
Mizoguchi, E.4
Mobisson, K.5
Simpson, S.6
Terhorst, C.7
Wishart, W.8
Golan, D.E.9
Bhan, A.K.10
Burakoff, S.J.11
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51
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0032142799
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Regulation of IL-4 expression by activation of individual alleles
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Here, one IL-4 allele was replaced by targeting experiments with a cDNA encoding the human CD2. Most Th2-enriched cells express either the IL-4 or the targeted allele, suggesting monoallelic transcription.
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Riviere I, Sunshine MJ, Littman DR Regulation of IL-4 expression by activation of individual alleles. Immunity. 9:1998;217-228. Here, one IL-4 allele was replaced by targeting experiments with a cDNA encoding the human CD2. Most Th2-enriched cells express either the IL-4 or the targeted allele, suggesting monoallelic transcription.
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(1998)
Immunity
, vol.9
, pp. 217-228
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Riviere, I.1
Sunshine, M.J.2
Littman, D.R.3
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52
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0032575727
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+ T Cells
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+ T cells express IL-4 either biallelically or monoallelically from either allele in a clonal manner.
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+ T cells express IL-4 either biallelically or monoallelically from either allele in a clonal manner.
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(1998)
Science
, vol.281
, pp. 1352-1354
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Bix, M.1
Locksley, R.M.2
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