메뉴 건너뛰기




Volumn 153, Issue 4, 1998, Pages 1041-1053

Histopathological evaluation of apoptosis in cancer

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CYSTEINE PROTEINASE; ONCOPROTEIN; PROTEIN BCL 2; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 0031691804     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)65649-0     Document Type: Review
Times cited : (219)

References (171)
  • 1
    • 0015383455 scopus 로고
    • Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
    • JFR Kerr AH Wyllie AR Currie Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics Br J Cancer 26 1972 239 257
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, JFR1    Wyllie, AH2    Currie, AR3
  • 2
    • 0028891783 scopus 로고
    • Apoptosis, oncosis, and necrosis: an overview of cell death
    • G Majno I Joris Apoptosis, oncosis, and necrosis: an overview of cell death Am J Pathol 146 1995 3 15
    • (1995) Am J Pathol , vol.146 , pp. 3-15
    • Majno, G1    Joris, I2
  • 4
    • 0028329172 scopus 로고
    • Apoptosis: its significance in cancer and cancer therapy
    • JFR Kerr CM Winterford BV Harmon Apoptosis: its significance in cancer and cancer therapy Cancer 73 1994 2013 2026
    • (1994) Cancer , vol.73 , pp. 2013-2026
    • Kerr, JFR1    Winterford, CM2    Harmon, BV3
  • 5
    • 0030046508 scopus 로고    scopus 로고
    • Life, death, and the pursuit of apoptosis
    • E White Life, death, and the pursuit of apoptosis Gene Dev 10 1996 1 15
    • (1996) Gene Dev , vol.10 , pp. 1-15
    • White, E1
  • 6
    • 0029899181 scopus 로고    scopus 로고
    • Molecular thanatopsis: a discourse on the BCL2 family and cell death
    • E Yang SJ Korsmeyer Molecular thanatopsis: a discourse on the BCL2 family and cell death Blood 88 1996 386 401
    • (1996) Blood , vol.88 , pp. 386-401
    • Yang, E1    Korsmeyer, SJ2
  • 7
    • 0030785790 scopus 로고    scopus 로고
    • The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis
    • SA Susin N Zamzami M Castedo E Daugas H-G Wang S Geley F Fassy JC Reed G Kroemer The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis J Exp Med 186 1997 25 37
    • (1997) J Exp Med , vol.186 , pp. 25-37
    • Susin, SA1    Zamzami, N2    Castedo, M3    Daugas, E4    Wang, H-G5    Geley, S6    Fassy, F7    Reed, JC8    Kroemer, G9
  • 8
    • 0031561136 scopus 로고    scopus 로고
    • The shape of cell death (breakthroughs and views)
    • M Leist P Nicotera The shape of cell death (breakthroughs and views) Biochem Biophys Res Commun 236 1997 1 9
    • (1997) Biochem Biophys Res Commun , vol.236 , pp. 1-9
    • Leist, M1    Nicotera, P2
  • 9
    • 0028147070 scopus 로고
    • Programmed cell death in Caenorhabditis elegans
    • MO Hengartner HR Horvitz Programmed cell death in Caenorhabditis elegans Curr Opin Genet Dev 4 1994 581 586
    • (1994) Curr Opin Genet Dev , vol.4 , pp. 581-586
    • Hengartner, MO1    Horvitz, HR2
  • 10
    • 0028673393 scopus 로고
    • The genetics of programmed cell death in the nematode Caenorhabditis elegans
    • HR Horvitz S Shaham MO Hengartner The genetics of programmed cell death in the nematode Caenorhabditis elegans Cold Spring Harbor Symp Quant Biol 59 1994 377 385
    • (1994) Cold Spring Harbor Symp Quant Biol , vol.59 , pp. 377-385
    • Horvitz, HR1    Shaham, S2    Hengartner, MO3
  • 11
    • 0031148667 scopus 로고    scopus 로고
    • Apoptosis: Bcl-2 related proteins get connected
    • MD Jacobson Apoptosis: Bcl-2 related proteins get connected Curr Biol 7 1997 R277 R281
    • (1997) Curr Biol , vol.7 , pp. R277-R281
    • Jacobson, MD1
  • 12
    • 0030740251 scopus 로고    scopus 로고
    • CED-4: the third horseman of apoptosis
    • DL Vaux CED-4: the third horseman of apoptosis Cell 90 1997 389 390
    • (1997) Cell , vol.90 , pp. 389-390
    • Vaux, DL1
  • 13
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
    • H Zou WJ Henzel X Liu A Lutschg X Wang Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3 Cell 90 1997 405 413
    • (1997) Cell , vol.90 , pp. 405-413
    • Zou, H1    Henzel, WJ2    Liu, X3    Lutschg, A4    Wang, X5
  • 14
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • CB Thompson Apoptosis in the pathogenesis and treatment of disease Science 267 1995 1456 1462
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, CB1
  • 15
    • 0028915454 scopus 로고
    • Regulation of lymphocyte survival by the bcl-2 gene family
    • S Cory Regulation of lymphocyte survival by the bcl-2 gene family Annu Rev Immunol 13 1995 513 543
    • (1995) Annu Rev Immunol , vol.13 , pp. 513-543
    • Cory, S1
  • 16
    • 0026802011 scopus 로고
    • Hormone-regulated apoptosis results from reentry of differentiated prostate cells onto a defective cell cycle
    • M Colombel CA Olsson P-Y Ng R Buttyan Hormone-regulated apoptosis results from reentry of differentiated prostate cells onto a defective cell cycle Cancer Res 52 1992 4313 4319
    • (1992) Cancer Res , vol.52 , pp. 4313-4319
    • Colombel, M1    Olsson, CA2    Ng, P-Y3    Buttyan, R4
  • 17
    • 0029048177 scopus 로고
    • MCF-7 human mammary adenocarcinoma cell death in vitro in response to hormone-withdrawal and DNA damage
    • JW Wilson AE Wakeling ID Morris JA Hickman C Dive MCF-7 human mammary adenocarcinoma cell death in vitro in response to hormone-withdrawal and DNA damage Int J Cancer 61 1995 502 508
    • (1995) Int J Cancer , vol.61 , pp. 502-508
    • Wilson, JW1    Wakeling, AE2    Morris, ID3    Hickman, JA4    Dive, C5
  • 18
    • 0028932731 scopus 로고
    • The CTL's kiss of death
    • G Berke The CTL's kiss of death Cell 81 1995 9 12
    • (1995) Cell , vol.81 , pp. 9-12
    • Berke, G1
  • 19
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • T Miyashita JC Reed Tumor suppressor p53 is a direct transcriptional activator of the human bax gene Cell 80 1995 293 299
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T1    Reed, JC2
  • 21
    • 0030808984 scopus 로고    scopus 로고
    • Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase
    • JL Kummer PK Rao KA Heidenreich Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase J Biol Chem 272 1997 20490 20494
    • (1997) J Biol Chem , vol.272 , pp. 20490-20494
    • Kummer, JL1    Rao, PK2    Heidenreich, KA3
  • 23
    • 0027994349 scopus 로고
    • The sphingomyelin cycle and the second messenger function of ceramide
    • YA Hannun The sphingomyelin cycle and the second messenger function of ceramide J Biol Chem 269 1994 3125 3128
    • (1994) J Biol Chem , vol.269 , pp. 3125-3128
    • Hannun, YA1
  • 24
    • 0030448021 scopus 로고    scopus 로고
    • Functions of ceramide in coordinating cellular responses to stress
    • YA Hannun Functions of ceramide in coordinating cellular responses to stress Science 274 1996 1855 1859
    • (1996) Science , vol.274 , pp. 1855-1859
    • Hannun, YA1
  • 26
    • 0029995766 scopus 로고    scopus 로고
    • A license to kill
    • A Fraser G Evan A license to kill Cell 85 1996 781 784
    • (1996) Cell , vol.85 , pp. 781-784
    • Fraser, A1    Evan, G2
  • 27
    • 0029664296 scopus 로고    scopus 로고
    • ICE family proteases: mediators of all apoptotic cell death?
    • PA Henkart ICE family proteases: mediators of all apoptotic cell death? Immunity 4 1996 195 201
    • (1996) Immunity , vol.4 , pp. 195-201
    • Henkart, PA1
  • 28
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • S Nagata Apoptosis by death factor Cell 88 1997 355 365
    • (1997) Cell , vol.88 , pp. 355-365
    • Nagata, S1
  • 30
    • 0031007840 scopus 로고    scopus 로고
    • Differential involvement of caspases in apoptosis of myeloid leukemic cells induced by chemotherapy versus growth factor withdrawal
    • RMY Barge R Willemze P Vandenabeele W Fiers R Beyaert Differential involvement of caspases in apoptosis of myeloid leukemic cells induced by chemotherapy versus growth factor withdrawal FEBS Lett 409 1997 207 210
    • (1997) FEBS Lett , vol.409 , pp. 207-210
    • Barge, RMY1    Willemze, R2    Vandenabeele, P3    Fiers, W4    Beyaert, R5
  • 31
    • 0030915095 scopus 로고    scopus 로고
    • Functional activation of Nedd2/ICH-1 (caspase-2) is an early process in apoptosis
    • NL Harvey AJ Butt S Kumar Functional activation of Nedd2/ICH-1 (caspase-2) is an early process in apoptosis J Biol Chem 272 1997 13134 13139
    • (1997) J Biol Chem , vol.272 , pp. 13134-13139
    • Harvey, NL1    Butt, AJ2    Kumar, S3
  • 32
    • 0028179134 scopus 로고
    • Inactivation of interleukin-1β converting enzyme by peptide (acyloxy)methyl ketones
    • NA Thornberry EP Peterson JJ Zhao AD Howard PR Griffin KT Chapman Inactivation of interleukin-1β converting enzyme by peptide (acyloxy)methyl ketones Biochemistry 33 1994 3934 3940
    • (1994) Biochemistry , vol.33 , pp. 3934-3940
    • Thornberry, NA1    Peterson, EP2    Zhao, JJ3    Howard, AD4    Griffin, PR5    Chapman, KT6
  • 33
    • 0029927422 scopus 로고    scopus 로고
    • The role of proteases during apoptosis
    • T Patel GJ Gores SH Kaufmann The role of proteases during apoptosis FASEB J 10 1996 587 597
    • (1996) FASEB J , vol.10 , pp. 587-597
    • Patel, T1    Gores, GJ2    Kaufmann, SH3
  • 35
    • 0030465544 scopus 로고    scopus 로고
    • Lamin proteolysis facilitates nuclear events during apoptosis
    • L Rao D Perez E White Lamin proteolysis facilitates nuclear events during apoptosis J Cell Biol 135 1996 1441 1455
    • (1996) J Cell Biol , vol.135 , pp. 1441-1455
    • Rao, L1    Perez, D2    White, E3
  • 36
    • 0030707519 scopus 로고    scopus 로고
    • Dismantling cell-cell contacts during apoptosis is coupled to a caspase-dependent proteolytic cleavage of β-catenin
    • C Brancolini D Lazarevic J Rodriguez C Schneider Dismantling cell-cell contacts during apoptosis is coupled to a caspase-dependent proteolytic cleavage of β-catenin J Cell Biol 139 1997 759 771
    • (1997) J Cell Biol , vol.139 , pp. 759-771
    • Brancolini, C1    Lazarevic, D2    Rodriguez, J3    Schneider, C4
  • 37
    • 0030770449 scopus 로고    scopus 로고
    • Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis
    • C Caulín GS Salvesen RG Oshima Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis J Cell Biol 138 1997 1379 1394
    • (1997) J Cell Biol , vol.138 , pp. 1379-1394
    • Caulín, C1    Salvesen, GS2    Oshima, RG3
  • 38
    • 0030955170 scopus 로고    scopus 로고
    • Proteolytic cleavage of the mdm2 oncoprotein during apoptosis
    • L Chen V Marechal J Moreau AJ Levine J Chen Proteolytic cleavage of the mdm2 oncoprotein during apoptosis J Biol Chem 272 1997 22966 22973
    • (1997) J Biol Chem , vol.272 , pp. 22966-22973
    • Chen, L1    Marechal, V2    Moreau, J3    Levine, AJ4    Chen, J5
  • 39
    • 0030899360 scopus 로고    scopus 로고
    • Degradation of retinoblastoma protein in tumor necrosis factor- and CD95-induced cell death
    • X Tan SJ Martin DR Green JYJ Wang Degradation of retinoblastoma protein in tumor necrosis factor- and CD95-induced cell death J Biol Chem 272 1997 9613 9616
    • (1997) J Biol Chem , vol.272 , pp. 9613-9616
    • Tan, X1    Martin, SJ2    Green, DR3    Wang, JYJ4
  • 40
    • 0031888955 scopus 로고    scopus 로고
    • A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
    • M Enari H Sakahira H Yokoyama K Okawa A Iwamatsu S Nagata A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD Nature 391 1998 43 50
    • (1998) Nature , vol.391 , pp. 43-50
    • Enari, M1    Sakahira, H2    Yokoyama, H3    Okawa, K4    Iwamatsu, A5    Nagata, S6
  • 41
    • 0028605481 scopus 로고
    • Bcl-2 in cancer, development and apoptosis
    • DM Hockenbery Bcl-2 in cancer, development and apoptosis J Cell Sci 18 Suppl 1994 51 55
    • (1994) J Cell Sci , vol.18 , Issue.Suppl , pp. 51-55
    • Hockenbery, DM1
  • 42
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • JC Reed Bcl-2 and the regulation of programmed cell death J Cell Biol 124 1994 1 6
    • (1994) J Cell Biol , vol.124 , pp. 1-6
    • Reed, JC1
  • 43
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene bcl-2 and its role in regulating apoptosis
    • G Kroemer The proto-oncogene bcl-2 and its role in regulating apoptosis Nat Med 3 1997 614 620
    • (1997) Nat Med , vol.3 , pp. 614-620
    • Kroemer, G1
  • 45
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • ZN Oltvai CL Milliman SJ Korsmeyer Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death Cell 74 1993 609 619
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, ZN1    Milliman, CL2    Korsmeyer, SJ3
  • 46
    • 0028206341 scopus 로고
    • BH1, and BH2 domains of bcl-2, are required for inhibition of apoptosis, and heterodimerization with bax
    • X-M Yin ZN Oltvai SJ Korsmeyer BH1, and BH2 domains of bcl-2, are required for inhibition of apoptosis, and heterodimerization with bax Nature 369 1994 321 323
    • (1994) Nature , vol.369 , pp. 321-323
    • Yin, X-M1    Oltvai, ZN2    Korsmeyer, SJ3
  • 48
    • 0030070342 scopus 로고    scopus 로고
    • Bcl-2: role in epithelial differentiation and oncogenesis
    • Q-L Lu P Abel CS Foster E-N Lalani Bcl-2: role in epithelial differentiation and oncogenesis Hum Pathol 27 1996 102 110
    • (1996) Hum Pathol , vol.27 , pp. 102-110
    • Lu, Q-L1    Abel, P2    Foster, CS3    Lalani, E-N4
  • 49
    • 0029033866 scopus 로고
    • Regulation of bcl-2 expression by oncogenic ras protein in hematopoietic cells
    • T Kinoshita T Yokota K-i Arai A Miyajima Regulation of bcl-2 expression by oncogenic ras protein in hematopoietic cells Oncogene 10 1995 2207 2212
    • (1995) Oncogene , vol.10 , pp. 2207-2212
    • Kinoshita, T1    Yokota, T2    Arai, K-i3    Miyajima, A4
  • 50
    • 0031034517 scopus 로고    scopus 로고
    • In bone marrow derived baf-3 cells, inhibition of apoptosis by IL-3 is mediated by two independent pathways
    • Y Leverrier J Thomas GR Perkins M Mangeney MKL Collins J Marvel In bone marrow derived baf-3 cells, inhibition of apoptosis by IL-3 is mediated by two independent pathways Oncogene 14 1997 425 430
    • (1997) Oncogene , vol.14 , pp. 425-430
    • Leverrier, Y1    Thomas, J2    Perkins, GR3    Mangeney, M4    Collins, MKL5    Marvel, J6
  • 51
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • D Hockenbery G Nuñez C Milliman RD Schreiber SJ Korsmeyer Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death Nature 348 1990 334 336
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D1    Nuñez, G2    Milliman, C3    Schreiber, RD4    Korsmeyer, SJ5
  • 52
    • 0030698810 scopus 로고    scopus 로고
    • The apoptosis-necrosis paradox: apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death
    • T Hirsch P Marchetti SA Susin B Dallaporta N Zamzami I Marzo M Geuskens G Kroemer The apoptosis-necrosis paradox: apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death Oncogene 15 1997 1573 1581
    • (1997) Oncogene , vol.15 , pp. 1573-1581
    • Hirsch, T1    Marchetti, P2    Susin, SA3    Dallaporta, B4    Zamzami, N5    Marzo, I6    Geuskens, M7    Kroemer, G8
  • 54
    • 0031036872 scopus 로고    scopus 로고
    • Prevention of apoptosis by bcl-2: release of cytochrome c from mitochondria blocked
    • J Yang X Liu K Bhalla CN Kim AM Ibrado J Cai T-I Peng DP Jones X Wang Prevention of apoptosis by bcl-2: release of cytochrome c from mitochondria blocked Science 275 1997 1129 1132
    • (1997) Science , vol.275 , pp. 1129-1132
    • Yang, J1    Liu, X2    Bhalla, K3    Kim, CN4    Ibrado, AM5    Cai, J6    Peng, T-I7    Jones, DP8    Wang, X9
  • 55
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: a primary site for bcl-2 regulation of apoptosis
    • RM Kluck E Bossy-Wetzel DR Green DD Newmeyer The release of cytochrome c from mitochondria: a primary site for bcl-2 regulation of apoptosis Science 275 1997 1132 1136
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, RM1    Bossy-Wetzel, E2    Green, DR3    Newmeyer, DD4
  • 56
    • 0030777253 scopus 로고    scopus 로고
    • Release of cytochrome c and decrease of cytochrome c oxidase in bax-expressing yeast cells, and prevention of these effects by coexpression of bcl-xL
    • L FEBS Lett 415 1997 29 32
    • (1997) FEBS Lett , vol.415 , pp. 29-32
    • Manon, S1    Chaudhuri, B2    Guérin, M3
  • 58
    • 0021821903 scopus 로고
    • Involvement of the bcl-2 gene in human follicular lymphoma
    • Y Tsujimoto J Cossman E Jaffe CM Croce Involvement of the bcl-2 gene in human follicular lymphoma Science 228 1985 1440 1443
    • (1985) Science , vol.228 , pp. 1440-1443
    • Tsujimoto, Y1    Cossman, J2    Jaffe, E3    Croce, CM4
  • 59
    • 0031018674 scopus 로고    scopus 로고
    • Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
    • N Rampino H Yamamoto Y Ionov Y Li H Sawai JC Reed M Perucho Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype Science 275 1997 967 969
    • (1997) Science , vol.275 , pp. 967-969
    • Rampino, N1    Yamamoto, H2    Ionov, Y3    Li, Y4    Sawai, H5    Reed, JC6    Perucho, M7
  • 60
    • 0027109075 scopus 로고
    • p53, guardian of the genome
    • DP Lane p53, guardian of the genome Nature 358 1992 15 16
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, DP1
  • 61
    • 0025111068 scopus 로고
    • Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53
    • D Michalovitz O Halevy M Oren Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53 Cell 62 1990 671 680
    • (1990) Cell , vol.62 , pp. 671-680
    • Michalovitz, D1    Halevy, O2    Oren, M3
  • 62
    • 0026093164 scopus 로고
    • Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein
    • J Martinez I Georgoff J Martinez AJ Levine Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein Genes Dev 5 1991 151 159
    • (1991) Genes Dev , vol.5 , pp. 151-159
    • Martinez, J1    Georgoff, I2    Martinez, J3    Levine, AJ4
  • 64
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • JW Harper GR Adami N Wei K Keyomarsi SJ Elledge The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases Cell 75 1993 805 816
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, JW1    Adami, GR2    Wei, N3    Keyomarsi, K4    Elledge, SJ5
  • 67
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • E Yonish-Rouach D Resnitzky J Lotem L Sachs A Kimchi M Oren Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6 Nature 352 1991 345 347
    • (1991) Nature , vol.352 , pp. 345-347
    • Yonish-Rouach, E1    Resnitzky, D2    Lotem, J3    Sachs, L4    Kimchi, A5    Oren, M6
  • 68
    • 0031253967 scopus 로고    scopus 로고
    • On the TRAIL from p53 to apoptosis?
    • M Kastan On the TRAIL from p53 to apoptosis? Nat Genet 17 1997 130 131
    • (1997) Nat Genet , vol.17 , pp. 130-131
    • Kastan, M1
  • 72
    • 0030889919 scopus 로고    scopus 로고
    • Activation of the K-ras oncogene in colorectal neoplasms is associated with decreased apoptosis
    • RL Ward AV Todd F Santiago T O'Connor NJ Hawkins Activation of the K-ras oncogene in colorectal neoplasms is associated with decreased apoptosis Cancer 79 1997 1106 1113
    • (1997) Cancer , vol.79 , pp. 1106-1113
    • Ward, RL1    Todd, AV2    Santiago, F3    O'Connor, T4    Hawkins, NJ5
  • 73
    • 0030048476 scopus 로고    scopus 로고
    • Phosphorylation of bcl-2 protein and association with p21Ras in Ras-induced apoptosis
    • Ras in Ras-induced apoptosis J Biol Chem 271 1996 2376 2379
    • (1996) J Biol Chem , vol.271 , pp. 2376-2379
    • Chen, C-Y1    Faller, DV2
  • 74
    • 0029001888 scopus 로고
    • Induction of DNA fragmentation after 10 to 120 minutes of focal cerebral ischemia in rats
    • Y Li M Chopp N Jiang ZG Zhang C Zaloga Induction of DNA fragmentation after 10 to 120 minutes of focal cerebral ischemia in rats Stroke 26 1995 1252 1257
    • (1995) Stroke , vol.26 , pp. 1252-1257
    • Li, Y1    Chopp, M2    Jiang, N3    Zhang, ZG4    Zaloga, C5
  • 75
    • 0030900980 scopus 로고    scopus 로고
    • Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis
    • M Leist B Single AF Castoldi S Kühnle P Nicotera Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis J Exp Med 185 1997 1481 1486
    • (1997) J Exp Med , vol.185 , pp. 1481-1486
    • Leist, M1    Single, B2    Castoldi, AF3    Kühnle, S4    Nicotera, P5
  • 76
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Y Gavrieli Y Sherman SA Ben-Sasson Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation J Cell Biol 119 1992 493 501
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y1    Sherman, Y2    Ben-Sasson, SA3
  • 77
    • 0027163053 scopus 로고
    • Detection of DNA fragmentation in apoptosis: application of in situ nick translation to cell culture systems and tissue sections
    • R Gold M Schmied G Rothe H Zischler H Breitschopf H Wekerle H Lassmann Detection of DNA fragmentation in apoptosis: application of in situ nick translation to cell culture systems and tissue sections J Histochem Cytochem 41 1993 1023 1030
    • (1993) J Histochem Cytochem , vol.41 , pp. 1023-1030
    • Gold, R1    Schmied, M2    Rothe, G3    Zischler, H4    Breitschopf, H5    Wekerle, H6    Lassmann, H7
  • 79
    • 0027191429 scopus 로고
    • In situ end-labelling detects DNA strand breaks in apoptosis, and other physiological, and pathological states
    • B Ansari PJ Coates BD Greenstein PA Hall In situ end-labelling detects DNA strand breaks in apoptosis, and other physiological, and pathological states J Pathol 170 1993 1 8
    • (1993) J Pathol , vol.170 , pp. 1-8
    • Ansari, B1    Coates, PJ2    Greenstein, BD3    Hall, PA4
  • 81
  • 82
    • 0028559479 scopus 로고
    • Apoptosis in breast cancer as related to histopathological characteristics and prognosis
    • P Lipponen S Aaltomaa V-M Kosma K Syrjänen Apoptosis in breast cancer as related to histopathological characteristics and prognosis Eur J Cancer 30A 1994 2068 2073
    • (1994) Eur J Cancer , vol.30A , pp. 2068-2073
    • Lipponen, P1    Aaltomaa, S2    Kosma, V-M3    Syrjänen, K4
  • 84
    • 0029848277 scopus 로고    scopus 로고
    • What is an apoptotic index measuring? (a commentary)
    • CS Potten What is an apoptotic index measuring? (a commentary) Br J Cancer 74 1996 1743 1748
    • (1996) Br J Cancer , vol.74 , pp. 1743-1748
    • Potten, CS1
  • 86
    • 0029808372 scopus 로고    scopus 로고
    • The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand
    • J O'Connell GC O'Sullivan JK Collins F Shanahan The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand J Exp Med 184 1996 1075 1082
    • (1996) J Exp Med , vol.184 , pp. 1075-1082
    • O'Connell, J1    O'Sullivan, GC2    Collins, JK3    Shanahan, F4
  • 87
    • 0027985477 scopus 로고
    • A study of apoptosis in normal and pathologic nervous tissue after in situ end-labeling of DNA strand breaks
    • A Migheli P Cavalla S Marino D Schiffer A study of apoptosis in normal and pathologic nervous tissue after in situ end-labeling of DNA strand breaks J Neuropathol Exp Neurol 53 1994 606 616
    • (1994) J Neuropathol Exp Neurol , vol.53 , pp. 606-616
    • Migheli, A1    Cavalla, P2    Marino, S3    Schiffer, D4
  • 88
    • 0029589848 scopus 로고
    • Two in situ labeling techniques reveal different patterns of DNA fragmentation during spontaneous apoptosis in vivo, and induced apoptosis in vitro
    • SD Mundle XZ Gao S Khan SA Gregory HD Preisler A Raza Two in situ labeling techniques reveal different patterns of DNA fragmentation during spontaneous apoptosis in vivo, and induced apoptosis in vitro Anticancer Res 15 1995 1895 1904
    • (1995) Anticancer Res , vol.15 , pp. 1895-1904
    • Mundle, SD1    Gao, XZ2    Khan, S3    Gregory, SA4    Preisler, HD5    Raza, A6
  • 89
    • 84939097279 scopus 로고
    • Effect of postmortem interval on in situ end-labeling of DNA oligonucleosomes
    • CK Petito B Roberts Effect of postmortem interval on in situ end-labeling of DNA oligonucleosomes J Neuropathol Exp Neurol 54 1995 761 765
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 761-765
    • Petito, CK1    Roberts, B2
  • 90
    • 51249167530 scopus 로고
    • In situ end labeling, and its applications to the study of endocrine disease: How can we study programmed cell death in surgical pathology materials?
    • H Sasano In situ end labeling, and its applications to the study of endocrine disease: How can we study programmed cell death in surgical pathology materials? Endocrinol Pathol 6 1995 87 89
    • (1995) Endocrinol Pathol , vol.6 , pp. 87-89
    • Sasano, H1
  • 91
    • 0029294613 scopus 로고
    • In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note
    • B Grasl-Kraupp B Ruttkay-Nedecky H Koudelka K Bukowska W Bursch R Schulte-Hermann In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note Hepatology 21 1995 1465 1468
    • (1995) Hepatology , vol.21 , pp. 1465-1468
    • Grasl-Kraupp, B1    Ruttkay-Nedecky, B2    Koudelka, H3    Bukowska, K4    Bursch, W5    Schulte-Hermann, R6
  • 92
    • 0029566202 scopus 로고
    • The effects of formalin fixation on the detection of apoptosis in human brain by in situ end-labelling of DNA
    • FD Davison M Groves F Scaravilli The effects of formalin fixation on the detection of apoptosis in human brain by in situ end-labelling of DNA Histochem J 27 1995 983 988
    • (1995) Histochem J , vol.27 , pp. 983-988
    • Davison, FD1    Groves, M2    Scaravilli, F3
  • 93
    • 0030954446 scopus 로고    scopus 로고
    • Detection of apoptosis in colorectal carcinoma by light microscopy and in situ end labelling
    • NJ Hawkins J Lees RL Ward Detection of apoptosis in colorectal carcinoma by light microscopy and in situ end labelling Anal Quant Cytol Histol 19 1997 227 232
    • (1997) Anal Quant Cytol Histol , vol.19 , pp. 227-232
    • Hawkins, NJ1    Lees, J2    Ward, RL3
  • 94
    • 0031912154 scopus 로고    scopus 로고
    • Apoptosis is inversely related to bcl-2 but not to bax expression in salivary gland tumours
    • Y Soini U Törmänen P Pääkkö Apoptosis is inversely related to bcl-2 but not to bax expression in salivary gland tumours Histopathology 32 1998 28 34
    • (1998) Histopathology , vol.32 , pp. 28-34
    • Soini, Y1    Törmänen, U2    Pääkkö, P3
  • 96
    • 0029847287 scopus 로고    scopus 로고
    • Correlation between apoptosis, proliferation and bcl-2 expression in malignant non-Hodgkin's lymphoma
    • SW Kiberu JH Pringle S Sobolewski P Murphy I Lauder Correlation between apoptosis, proliferation and bcl-2 expression in malignant non-Hodgkin's lymphoma J Clin Pathol Mol Pathol 49 1996 M268 M272
    • (1996) J Clin Pathol Mol Pathol , vol.49 , pp. M268-M272
    • Kiberu, SW1    Pringle, JH2    Sobolewski, S3    Murphy, P4    Lauder, I5
  • 97
    • 0031047174 scopus 로고    scopus 로고
    • Proliferation and apoptosis in primary gastric B-cell non-Hodgkin's lymphoma
    • IAM Gisbertz HC Schouten FJ Bot J-W Arends Proliferation and apoptosis in primary gastric B-cell non-Hodgkin's lymphoma Histopathology 30 1997 152 159
    • (1997) Histopathology , vol.30 , pp. 152-159
    • Gisbertz, IAM1    Schouten, HC2    Bot, FJ3    Arends, J-W4
  • 98
    • 0031917220 scopus 로고    scopus 로고
    • High grade malignant non-Hodgkin's lymphomas differ from low grade lymphomas in the extent of apoptosis and their expression of bcl-2, mcl-1, bax, and p53
    • Y Soini H Raunio P Pääkkö High grade malignant non-Hodgkin's lymphomas differ from low grade lymphomas in the extent of apoptosis and their expression of bcl-2, mcl-1, bax, and p53 Tumor Biol 19 1998 176 185
    • (1998) Tumor Biol , vol.19 , pp. 176-185
    • Soini, Y1    Raunio, H2    Pääkkö, P3
  • 103
    • 0024564527 scopus 로고
    • Detection of Epstein-Barr viral genomes in Reed-Sternberg cells of Hodgkin's disease
    • LM Weiss LA Movahed RA Warnke J Sklar Detection of Epstein-Barr viral genomes in Reed-Sternberg cells of Hodgkin's disease N Engl J Med 320 1989 502 506
    • (1989) N Engl J Med , vol.320 , pp. 502-506
    • Weiss, LM1    Movahed, LA2    Warnke, RA3    Sklar, J4
  • 104
    • 0025422532 scopus 로고
    • Lymphoepithelial carcinoma of the stomach with Epstein-Barr virus demonstrated by polymerase chain reaction
    • AP Burke TS Yen KM Shekitka LH Sobin Lymphoepithelial carcinoma of the stomach with Epstein-Barr virus demonstrated by polymerase chain reaction Mod Pathol 3 1990 377 380
    • (1990) Mod Pathol , vol.3 , pp. 377-380
    • Burke, AP1    Yen, TS2    Shekitka, KM3    Sobin, LH4
  • 105
    • 0025772343 scopus 로고
    • Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death
    • S Henderson M Rowe C Gregory D Croom-Carter F Wang R Longnecker E Kieff A Rickinson Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death Cell 65 1991 1107 1115
    • (1991) Cell , vol.65 , pp. 1107-1115
    • Henderson, S1    Rowe, M2    Gregory, C3    Croom-Carter, D4    Wang, F5    Longnecker, R6    Kieff, E7    Rickinson, A8
  • 106
    • 0030768893 scopus 로고    scopus 로고
    • The extent of apoptosis is inversely associated with bcl-2 expression in premalignant and malignant breast lesions
    • M Mustonen H Raunio P Pääkkö Y Soini The extent of apoptosis is inversely associated with bcl-2 expression in premalignant and malignant breast lesions Histopathology 31 1997 347 354
    • (1997) Histopathology , vol.31 , pp. 347-354
    • Mustonen, M1    Raunio, H2    Pääkkö, P3    Soini, Y4
  • 107
    • 0027993895 scopus 로고
    • Bcl-2 immunoreactivity in breast carcinoma correlates with hormone receptor positivity
    • V Bhargava DL Kell M van de Rijn RA Warnke Bcl-2 immunoreactivity in breast carcinoma correlates with hormone receptor positivity Am J Pathol 145 1994 535 540
    • (1994) Am J Pathol , vol.145 , pp. 535-540
    • Bhargava, V1    Kell, DL2    van de Rijn, M3    Warnke, RA4
  • 108
    • 0031018983 scopus 로고    scopus 로고
    • Estrogen increases intracellular p26Bcl-2 to p21Bax ratios and inhibits taxol-induced apoptosis of human breast cancer MCF-7 cells
    • Y Huang S Ray JC Reed AM Ibrado C Tang A Nawabi K Bhalla Estrogen increases intracellular p26Bcl-2 to p21Bax ratios and inhibits taxol-induced apoptosis of human breast cancer MCF-7 cells Breast Cancer Res Treat 42 1997 73 81
    • (1997) Breast Cancer Res Treat , vol.42 , pp. 73-81
    • Huang, Y1    Ray, S2    Reed, JC3    Ibrado, AM4    Tang, C5    Nawabi, A6    Bhalla, K7
  • 109
    • 0027944957 scopus 로고
    • Bcl-2 protein expression and long-term survival in breast cancer
    • H Joensuu L Pylkkänen S Toikkanen Bcl-2 protein expression and long-term survival in breast cancer Am J Pathol 145 1994 1191 1198
    • (1994) Am J Pathol , vol.145 , pp. 1191-1198
    • Joensuu, H1    Pylkkänen, L2    Toikkanen, S3
  • 111
    • 0028848548 scopus 로고
    • Association between the apoptotic index and established prognostic parameters in endometrial adenocarcinoma
    • MK Heatley Association between the apoptotic index and established prognostic parameters in endometrial adenocarcinoma Histopathology 27 1995 469 472
    • (1995) Histopathology , vol.27 , pp. 469-472
    • Heatley, MK1
  • 112
    • 0029835824 scopus 로고    scopus 로고
    • Bcl-2 expression is correlated with a low apoptotic index and associated with progesterone receptor immunoreactivity in endometrial carcinomas
    • M Saegusa Y Kamata M Isono I Okayasu Bcl-2 expression is correlated with a low apoptotic index and associated with progesterone receptor immunoreactivity in endometrial carcinomas J Pathol 180 1996 275 282
    • (1996) J Pathol , vol.180 , pp. 275-282
    • Saegusa, M1    Kamata, Y2    Isono, M3    Okayasu, I4
  • 113
    • 0029972637 scopus 로고    scopus 로고
    • Bcl-2 expression and the development of endometrial carcinoma
    • DC Chhieng JS Ross RA Ambros Bcl-2 expression and the development of endometrial carcinoma Mod Pathol 9 1996 402 406
    • (1996) Mod Pathol , vol.9 , pp. 402-406
    • Chhieng, DC1    Ross, JS2    Ambros, RA3
  • 114
    • 0029882098 scopus 로고    scopus 로고
    • Bcl-2 is down-regulated in atypical endometrial hyperplasia and adenocarcinoma
    • GS Henderson KA Brown SL Perkins TM Abbott F Clayton Bcl-2 is down-regulated in atypical endometrial hyperplasia and adenocarcinoma Mod Pathol 9 1996 430 438
    • (1996) Mod Pathol , vol.9 , pp. 430-438
    • Henderson, GS1    Brown, KA2    Perkins, SL3    Abbott, TM4    Clayton, F5
  • 115
    • 0021718260 scopus 로고
    • Successive waves of apoptosis in the rat prostate after repeated withdrawal of testosterone stimulation
    • NL Sandford JW Searle JF Kerr Successive waves of apoptosis in the rat prostate after repeated withdrawal of testosterone stimulation Pathology 16 1984 406 410
    • (1984) Pathology , vol.16 , pp. 406-410
    • Sandford, NL1    Searle, JW2    Kerr, JF3
  • 116
    • 0025298231 scopus 로고
    • Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation
    • N Kyprianou HF English JT Isaacs Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation Cancer Res 50 1990 3748 3753
    • (1990) Cancer Res , vol.50 , pp. 3748-3753
    • Kyprianou, N1    English, HF2    Isaacs, JT3
  • 117
    • 0027093255 scopus 로고
    • Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer
    • TJ McDonnell P Troncoso SM Brisbay C Logothetis LWK Chung J-T Hsieh S-M Tu ML Campbell Expression of the protooncogene bcl -2 in the prostate and its association with emergence of androgen-independent prostate cancer Cancer Res 52 1992 6940 6944
    • (1992) Cancer Res , vol.52 , pp. 6940-6944
    • McDonnell, TJ1    Troncoso, P2    Brisbay, SM3    Logothetis, C4    Chung, LWK5    Hsieh, J-T6    Tu, S-M7    Campbell, ML8
  • 119
    • 0030879959 scopus 로고    scopus 로고
    • Increased cell proliferation activity and decreased cell death are associated with the emergence of hormone-refractory recurrent prostate cancer
    • P Koivisto T Visakorpi I Rantala J Isola Increased cell proliferation activity and decreased cell death are associated with the emergence of hormone-refractory recurrent prostate cancer J Pathol 183 1997 51 56
    • (1997) J Pathol , vol.183 , pp. 51-56
    • Koivisto, P1    Visakorpi, T2    Rantala, I3    Isola, J4
  • 121
    • 0028813448 scopus 로고
    • The frequency of apoptosis correlates with the prognosis of Gleason grade 3 adenocarcinoma of the prostate
    • M Aihara PT Scardino LD Truong TM Wheeler JR Goad G Yang TC Thompson The frequency of apoptosis correlates with the prognosis of Gleason grade 3 adenocarcinoma of the prostate Cancer 75 1995 522 529
    • (1995) Cancer , vol.75 , pp. 522-529
    • Aihara, M1    Scardino, PT2    Truong, LD3    Wheeler, TM4    Goad, JR5    Yang, G6    Thompson, TC7
  • 122
    • 0031051919 scopus 로고    scopus 로고
    • Apoptosis and proliferation in thyroid carcinoma: correlation with bcl-2 and p53 protein expression
    • F Basolo L Pollina G Fontanini L Fiore F Pacini A Baldanzi Apoptosis and proliferation in thyroid carcinoma: correlation with bcl-2 and p53 protein expression Br J Cancer 75 1997 537 541
    • (1997) Br J Cancer , vol.75 , pp. 537-541
    • Basolo, F1    Pollina, L2    Fontanini, G3    Fiore, L4    Pacini, F5    Baldanzi, A6
  • 123
    • 0028893785 scopus 로고
    • Cell proliferation and apoptosis in normal and pathologic human adrenal
    • H Sasano A Imatani S Shizawa T Suzuki H Nagura Cell proliferation and apoptosis in normal and pathologic human adrenal Mod Pathol 8 1995 11 17
    • (1995) Mod Pathol , vol.8 , pp. 11-17
    • Sasano, H1    Imatani, A2    Shizawa, S3    Suzuki, T4    Nagura, H5
  • 124
  • 126
    • 0031018119 scopus 로고    scopus 로고
    • Apoptosis, cell proliferation, and expression of Bcl-2, and Bax in gastric carcinomas: immunohistochemical and clinicopathological study
    • Y Koshida M Saegusa I Okayasu Apoptosis, cell proliferation, and expression of Bcl-2, and Bax in gastric carcinomas: immunohistochemical and clinicopathological study Br J Cancer 75 1997 367 373
    • (1997) Br J Cancer , vol.75 , pp. 367-373
    • Koshida, Y1    Saegusa, M2    Okayasu, I3
  • 127
    • 0030024253 scopus 로고    scopus 로고
    • Apoptosis and immunohistochemical bcl-2 expression in colorectal adenomas and carcinomas: aspects of carcinogenesis and prognostic significance
    • GB Baretton J Diebold G Christoforis M Vogt C Müller K Dopfer K Schneiderbanger M Schmidt U Löhrs Apoptosis and immunohistochemical bcl-2 expression in colorectal adenomas and carcinomas: aspects of carcinogenesis and prognostic significance Cancer 77 1996 255 264
    • (1996) Cancer , vol.77 , pp. 255-264
    • Baretton, GB1    Diebold, J2    Christoforis, G3    Vogt, M4    Müller, C5    Dopfer, K6    Schneiderbanger, K7    Schmidt, M8    Löhrs, U9
  • 129
    • 0029987762 scopus 로고    scopus 로고
    • Hepatocellular carcinomas with a high proliferation index and a low degree of apoptosis and necrosis are associated with a shortened survival
    • Y Soini N Virkajärvi V-P Lehto P Pääkkö Hepatocellular carcinomas with a high proliferation index and a low degree of apoptosis and necrosis are associated with a shortened survival Br J Cancer 73 1996 1025 1030
    • (1996) Br J Cancer , vol.73 , pp. 1025-1030
    • Soini, Y1    Virkajärvi, N2    Lehto, V-P3    Pääkkö, P4
  • 130
    • 0030779033 scopus 로고    scopus 로고
    • Association between p53 overexpression, cell proliferation, tumor necrosis and extent of apoptosis in operated pancreatic adenocarcinoma
    • N Virkajärvi P Pääkkö Y Soini Association between p53 overexpression, cell proliferation, tumor necrosis and extent of apoptosis in operated pancreatic adenocarcinoma APMIS 105 1997 765 772
    • (1997) APMIS , vol.105 , pp. 765-772
    • Virkajärvi, N1    Pääkkö, P2    Soini, Y3
  • 132
    • 0028145762 scopus 로고
    • Immunohistochemical detection of bcl-2 protein in liver lesions: Bcl-2 protein is expressed in hepatocellular carcinomas but not in liver cell dysplasia
    • M Zhao N-X Zhang M Economou I Blaha JA Laissue A Zimmermann Immunohistochemical detection of bcl-2 protein in liver lesions: Bcl-2 protein is expressed in hepatocellular carcinomas but not in liver cell dysplasia Histopathology 25 1994 237 245
    • (1994) Histopathology , vol.25 , pp. 237-245
    • Zhao, M1    Zhang, N-X2    Economou, M3    Blaha, I4    Laissue, JA5    Zimmermann, A6
  • 136
    • 0030057349 scopus 로고    scopus 로고
    • Apoptosis occurs independently of bcl-2 and p53 over-expression in non-small cell lung carcinoma
    • AJ O'Neill MJ Staunton EF Gaffney Apoptosis occurs independently of bcl-2 and p53 over-expression in non-small cell lung carcinoma Histopathology 29 1996 45 50
    • (1996) Histopathology , vol.29 , pp. 45-50
    • O'Neill, AJ1    Staunton, MJ2    Gaffney, EF3
  • 137
    • 0001929963 scopus 로고    scopus 로고
    • Apoptosis in non-small cell lung cancer as related to drug resistance and prognosis
    • G Stammler M Volm Apoptosis in non-small cell lung cancer as related to drug resistance and prognosis Apoptosis 1 1996 95 99
    • (1996) Apoptosis , vol.1 , pp. 95-99
    • Stammler, G1    Volm, M2
  • 138
    • 0028081924 scopus 로고
    • Expression of bcl-2 in small cell lung carcinoma cells
    • N Ikegaki M Katsumata J Minna Y Tsujimoto Expression of bcl-2 in small cell lung carcinoma cells Cancer Res 54 1994 6 8
    • (1994) Cancer Res , vol.54 , pp. 6-8
    • Ikegaki, N1    Katsumata, M2    Minna, J3    Tsujimoto, Y4
  • 139
    • 0030091651 scopus 로고    scopus 로고
    • Bcl-2 protein expression in lung cancer and close correlation with neuroendocrine differentiation
    • S-X Jiang T Kameya Y Sato N Yanase H Yoshimura T Kodama Bcl-2 protein expression in lung cancer and close correlation with neuroendocrine differentiation Am J Pathol 148 1996 837 846
    • (1996) Am J Pathol , vol.148 , pp. 837-846
    • Jiang, S-X1    Kameya, T2    Sato, Y3    Yanase, N4    Yoshimura, H5    Kodama, T6
  • 141
    • 0028960205 scopus 로고
    • Tumor type is a determinant of susceptibility to apoptosis
    • MJ Staunton EF Gaffney Tumor type is a determinant of susceptibility to apoptosis Am J Clin Pathol 103 1995 300 307
    • (1995) Am J Clin Pathol , vol.103 , pp. 300-307
    • Staunton, MJ1    Gaffney, EF2
  • 142
    • 0029655696 scopus 로고    scopus 로고
    • Incidence of apoptosis, cell proliferation and bcl-2 expression in transitional cell carcinoma of the bladder: association with tumor progression
    • ED King J Matteson SC Jacobs N Kyprianou Incidence of apoptosis, cell proliferation and bcl-2 expression in transitional cell carcinoma of the bladder: association with tumor progression J Urol 155 1996 316 320
    • (1996) J Urol , vol.155 , pp. 316-320
    • King, ED1    Matteson, J2    Jacobs, SC3    Kyprianou, N4
  • 143
    • 0030043995 scopus 로고    scopus 로고
    • Immunohistochemical analysis of bcl-2 expression in transitional cell carcinoma of the bladder
    • H Shiina M Igawa S Urakami S Honda H Shirakawa T Ishibe Immunohistochemical analysis of bcl-2 expression in transitional cell carcinoma of the bladder J Clin Pathol 49 1996 395 399
    • (1996) J Clin Pathol , vol.49 , pp. 395-399
    • Shiina, H1    Igawa, M2    Urakami, S3    Honda, S4    Shirakawa, H5    Ishibe, T6
  • 144
    • 0028949020 scopus 로고
    • Expression of tumour-suppressor gene Rb, apoptosis-suppressing protein bcl-2 and c-myc have no independent prognostic value in renal adenocarcinoma
    • P Lipponen M Eskelinen K Syrjänen Expression of tumour-suppressor gene Rb, apoptosis-suppressing protein bcl-2 and c-myc have no independent prognostic value in renal adenocarcinoma Br J Cancer 71 1995 863 867
    • (1995) Br J Cancer , vol.71 , pp. 863-867
    • Lipponen, P1    Eskelinen, M2    Syrjänen, K3
  • 147
    • 0029854194 scopus 로고    scopus 로고
    • Extent of apoptosis in relation to p53 and bcl-2 expression in germ cell tumors
    • Y Soini P Pääkkö Extent of apoptosis in relation to p53 and bcl-2 expression in germ cell tumors Hum Pathol 27 1996 1221 1226
    • (1996) Hum Pathol , vol.27 , pp. 1221-1226
    • Soini, Y1    Pääkkö, P2
  • 148
    • 0028811066 scopus 로고
    • Bcl-2 protein expression in the Barrett's metaplasia-dysplasia-carcinoma sequence
    • JR Goldblum TW Rice Bcl-2 protein expression in the Barrett's metaplasia-dysplasia-carcinoma sequence Mod Pathol 8 1995 866 869
    • (1995) Mod Pathol , vol.8 , pp. 866-869
    • Goldblum, JR1    Rice, TW2
  • 149
    • 0029620685 scopus 로고
    • Apoptosis in normal epithelium, premalignant and malignant lesions of the oropharynx and oral cavity: a preliminary study
    • MA Birchall CM Winterford DJ Allan BV Harmon Apoptosis in normal epithelium, premalignant and malignant lesions of the oropharynx and oral cavity: a preliminary study Oral Oncol Eur J Cancer 31B 1995 380 383
    • (1995) Oral Oncol Eur J Cancer , vol.31B , pp. 380-383
    • Birchall, MA1    Winterford, CM2    Allan, DJ3    Harmon, BV4
  • 150
    • 0029810311 scopus 로고    scopus 로고
    • Apoptosis in human gastric mucosa, chronic gastritis, dysplasia and carcinoma: analysis by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labelling
    • M Ishida Y Gomyo S Tatebe S Ohfuji H Ito Apoptosis in human gastric mucosa, chronic gastritis, dysplasia and carcinoma: analysis by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labelling Virchows Arch 428 1996 229 235
    • (1996) Virchows Arch , vol.428 , pp. 229-235
    • Ishida, M1    Gomyo, Y2    Tatebe, S3    Ohfuji, S4    Ito, H5
  • 151
    • 0029868847 scopus 로고    scopus 로고
    • Expression of bcl-2 protein in hyperplastic polyps, adenomas, and carcinomas of the colon
    • CC Flohil PA Janssen FT Bosman Expression of bcl-2 protein in hyperplastic polyps, adenomas, and carcinomas of the colon J Pathol 178 1996 393 397
    • (1996) J Pathol , vol.178 , pp. 393-397
    • Flohil, CC1    Janssen, PA2    Bosman, FT3
  • 152
    • 0028287243 scopus 로고
    • Immunohistochemical evidence of aberrant bcl-2 protein expression in gastric epithelial dysplasia
    • GY Lauwers GV Scott J Hendricks Immunohistochemical evidence of aberrant bcl-2 protein expression in gastric epithelial dysplasia Cancer 73 1994 2900 2904
    • (1994) Cancer , vol.73 , pp. 2900-2904
    • Lauwers, GY1    Scott, GV2    Hendricks, J3
  • 153
    • 0030755945 scopus 로고    scopus 로고
    • Loss of matrix adhesion triggers rapid transformation-selective apoptosis in fibroblasts
    • G McGill A Shimamura RC Bates RE Savage DE Fisher Loss of matrix adhesion triggers rapid transformation-selective apoptosis in fibroblasts J Cell Biol 138 1997 901 911
    • (1997) J Cell Biol , vol.138 , pp. 901-911
    • McGill, G1    Shimamura, A2    Bates, RC3    Savage, RE4    Fisher, DE5
  • 154
  • 155
    • 0030981411 scopus 로고    scopus 로고
    • Role of apoptosis in spontaneous regression of peripheral T-cell lymphoma arising in skin or subcutis
    • E Arai I Katayama Role of apoptosis in spontaneous regression of peripheral T-cell lymphoma arising in skin or subcutis Hum Pathol 28 1997 472 477
    • (1997) Hum Pathol , vol.28 , pp. 472-477
    • Arai, E1    Katayama, I2
  • 156
    • 0031030251 scopus 로고    scopus 로고
    • Apoptosis and its relation to the cell cycle in the developing cerebral cortex
    • D Thomaidou MC Mione JFR Cavanagh JG Parnavelas Apoptosis and its relation to the cell cycle in the developing cerebral cortex J Neurosci 17 1997 1075 1085
    • (1997) J Neurosci , vol.17 , pp. 1075-1085
    • Thomaidou, D1    Mione, MC2    Cavanagh, JFR3    Parnavelas, JG4
  • 157
    • 0028785885 scopus 로고
    • Overexpression of cyclin A in the mammary glands of transgenic mice results in the induction of nuclear abnormalities and increased apoptosis
    • DM Bortner MP Rosenberg Overexpression of cyclin A in the mammary glands of transgenic mice results in the induction of nuclear abnormalities and increased apoptosis Cell Growth Differ 6 1995 1579 1589
    • (1995) Cell Growth Differ , vol.6 , pp. 1579-1589
    • Bortner, DM1    Rosenberg, MP2
  • 158
    • 0029128927 scopus 로고
    • Induction of cyclin B and H1 kinase activity in apoptotic PC12 cells
    • CY Gao PS Zelenka Induction of cyclin B and H1 kinase activity in apoptotic PC12 cells Exp Cell Res 219 1995 612 618
    • (1995) Exp Cell Res , vol.219 , pp. 612-618
    • Gao, CY1    Zelenka, PS2
  • 159
    • 0029048745 scopus 로고
    • Apoptosis and the cell cycle
    • W Meikrantz R Schlegel Apoptosis and the cell cycle J Cell Biochem 58 1995 160 174
    • (1995) J Cell Biochem , vol.58 , pp. 160-174
    • Meikrantz, W1    Schlegel, R2
  • 160
    • 0030031514 scopus 로고    scopus 로고
    • Cyclin D1 is an essential mediator of apoptotic neuronal cell death
    • O Kranenburg AJ van der Eb A Zantema Cyclin D1 is an essential mediator of apoptotic neuronal cell death EMBO J 15 1996 46 54
    • (1996) EMBO J , vol.15 , pp. 46-54
    • Kranenburg, O1    van der Eb, AJ2    Zantema, A3
  • 161
    • 0030444208 scopus 로고    scopus 로고
    • Apoptosis induced by ectopic expression of cyclin D1 but not cyclin E
    • Y Sofer-Levi D Resnitzky Apoptosis induced by ectopic expression of cyclin D1 but not cyclin E Oncogene 13 1996 2431 2437
    • (1996) Oncogene , vol.13 , pp. 2431-2437
    • Sofer-Levi, Y1    Resnitzky, D2
  • 162
    • 0030844315 scopus 로고    scopus 로고
    • Apoptosis bcl-2 and p53 expression and their relation to tumour stage in non-small cell lung carcinomas (NSCLC)
    • HA Kargi S Aktas Ö Sağol S Ermete O Akpinar A Akkoclu Apoptosis bcl-2 and p53 expression and their relation to tumour stage in non-small cell lung carcinomas (NSCLC) Cancer Lett 116 1997 185 189
    • (1997) Cancer Lett , vol.116 , pp. 185-189
    • Kargi, HA1    Aktas, S2    Sağol, Ö3    Ermete, S4    Akpinar, O5    Akkoclu, A6
  • 163
    • 0028871622 scopus 로고
    • In situ end-labelling, light microscopic assessment, and ultrastructure of apoptosis in lung carcinoma
    • EF Gaffney AJ O'Neill MJ Staunton In situ end-labelling, light microscopic assessment, and ultrastructure of apoptosis in lung carcinoma J Clin Pathol 48 1995 1017 1021
    • (1995) J Clin Pathol , vol.48 , pp. 1017-1021
    • Gaffney, EF1    O'Neill, AJ2    Staunton, MJ3
  • 165
    • 0030070626 scopus 로고    scopus 로고
    • Apoptosis occurs more frequently in metastatic foci than in primary lesions of human colorectal carcinomas: analysis by terminal-deoxynucleotidyl-transferase mediated dUTP-biotin nick end labeling
    • S Tatebe M Ishida N Kasagi S Tsujitani N Kaibara H Ito Apoptosis occurs more frequently in metastatic foci than in primary lesions of human colorectal carcinomas: analysis by terminal-deoxynucleotidyl-transferase mediated dUTP-biotin nick end labeling Int J Cancer 65 1996 173 177
    • (1996) Int J Cancer , vol.65 , pp. 173-177
    • Tatebe, S1    Ishida, M2    Kasagi, N3    Tsujitani, S4    Kaibara, N5    Ito, H6
  • 167
    • 0030742170 scopus 로고    scopus 로고
    • Apoptosis in colorectal carcinoma occurring in patients aged 45 years and under: relationship to prognosis, mitosis, and immunohistochemical demonstration of p53, c-myc and bcl-2 protein products
    • NEI Langlois J Lamb O Eremin SD Heys Apoptosis in colorectal carcinoma occurring in patients aged 45 years and under: relationship to prognosis, mitosis, and immunohistochemical demonstration of p53, c-myc and bcl-2 protein products J Pathol 182 1997 392 397
    • (1997) J Pathol , vol.182 , pp. 392-397
    • Langlois, NEI1    Lamb, J2    Eremin, O3    Heys, SD4
  • 168
    • 0029840331 scopus 로고    scopus 로고
    • Perineural invasion of prostate carcinoma cells is associated with reduced apoptotic index
    • G Yang TM Wheeler MW Kattan PT Scardino TC Thompson Perineural invasion of prostate carcinoma cells is associated with reduced apoptotic index Cancer 78 1996 1267 1271
    • (1996) Cancer , vol.78 , pp. 1267-1271
    • Yang, G1    Wheeler, TM2    Kattan, MW3    Scardino, PT4    Thompson, TC5
  • 169
    • 0028857747 scopus 로고
    • Expression of bcl-2 oncogene protein is prevalent in small cell lung carcinomas
    • S-X Jiang Y Sato S Kuwao T Kameya Expression of bcl-2 oncogene protein is prevalent in small cell lung carcinomas J Pathol 177 1995 135 138
    • (1995) J Pathol , vol.177 , pp. 135-138
    • Jiang, S-X1    Sato, Y2    Kuwao, S3    Kameya, T4
  • 171
    • 0030443653 scopus 로고    scopus 로고
    • bcl-2 and p53 expression in resectable pancreatic adenocarcinomas: association with clinical outcome
    • FA Sinicrope DB Evans SD Leach KR Cleary CJ Fenoglio JJ Lee JL Abbruzzese bcl-2 and p53 expression in resectable pancreatic adenocarcinomas: association with clinical outcome Clin Cancer Res 2 1996 2015 2022
    • (1996) Clin Cancer Res , vol.2 , pp. 2015-2022
    • Sinicrope, FA1    Evans, DB2    Leach, SD3    Cleary, KR4    Fenoglio, CJ5    Lee, JJ6    Abbruzzese, JL7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.