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Volumn 15, Issue 1, 1996, Pages 46-54

Cyclin D1 is an essential mediator of apoptotic neuronal cell death

Author keywords

Apoptosis; cdk4; Cell cycle; Cyclin D1; Neuronal cell death

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLINE; ENZYME INHIBITOR; PROTEIN BCL 2; RETINOBLASTOMA PROTEIN; VIRUS PROTEIN;

EID: 0030031514     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00332.x     Document Type: Article
Times cited : (363)

References (65)
  • 1
    • 0027243086 scopus 로고
    • The protooncogene bcl2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis
    • Allsopp, T.E., Wyatt, S., Patterson, H.F. and Davies, A.M. (1993) The protooncogene bcl2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis. Cell, 73, 295-307.
    • (1993) Cell , vol.73 , pp. 295-307
    • Allsopp, T.E.1    Wyatt, S.2    Patterson, H.F.3    Davies, A.M.4
  • 2
    • 0029050533 scopus 로고
    • Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis
    • Almasan, A., Yin, Y., Kelly, R.E., Lee, E.Y.-H.P., Bradley, A., Li, W., Bertino, J R. and Wahl, G. (1995) Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis. Proc. Natl Acad. Sci. USA, 92, 5436-5440.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 5436-5440
    • Almasan, A.1    Yin, Y.2    Kelly, R.E.3    Lee, E.Y.-H.P.4    Bradley, A.5    Li, W.6    Bertino, J.R.7    Wahl, G.8
  • 3
    • 0025040233 scopus 로고
    • Suppression of human colorectal carcinoma cell growth by wild-type p53
    • Baker, S.J., Markowitz, S., Fearon, E.R., Willson, J.K.V. and Vogelstein, B. (1990) Suppression of human colorectal carcinoma cell growth by wild-type p53. Science, 249, 912-915.
    • (1990) Science , vol.249 , pp. 912-915
    • Baker, S.J.1    Markowitz, S.2    Fearon, E.R.3    Willson, J.K.V.4    Vogelstein, B.5
  • 4
    • 0027154638 scopus 로고
    • Cyclin D1 is a nuclear protein required for cell cycle progression in G1
    • Baldin, V, Lukas, J., Marcote, M.J., Pagano, M. and Draetta, G. (1993) Cyclin D1 is a nuclear protein required for cell cycle progression in G1. Genes Dev., 7, 812-821.
    • (1993) Genes Dev. , vol.7 , pp. 812-821
    • Baldin, V.1    Lukas, J.2    Marcote, M.J.3    Pagano, M.4    Draetta, G.5
  • 5
    • 0027985749 scopus 로고
    • E2F-4, a new member of the E2F gene family has oncogenic activity and associates with p107 in vivo
    • Beijersbergen, R.L., Kerkhoven, R.M., Zhu, L., Carlee, L., Voorhoeve, M. and Bernards, R (1994) E2F-4, a new member of the E2F gene family has oncogenic activity and associates with p107 in vivo. Genes Dev., 8, 2680-2690.
    • (1994) Genes Dev. , vol.8 , pp. 2680-2690
    • Beijersbergen, R.L.1    Kerkhoven, R.M.2    Zhu, L.3    Carlee, L.4    Voorhoeve, M.5    Bernards, R.6
  • 6
    • 0028274940 scopus 로고
    • Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphamogenesis with the myc gene
    • Bodrug, S.E., Warner, B.J , Bath, M L., Lindeman, G.J., Harris, A.W. and Adams, J.M. (1994) Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphamogenesis with the myc gene. EMBO J., 13, 2124-2130.
    • (1994) EMBO J. , vol.13 , pp. 2124-2130
    • Bodrug, S.E.1    Warner, B.J.2    Bath, M.L.3    Lindeman, G.J.4    Harris, A.W.5    Adams, J.M.6
  • 7
    • 0028983657 scopus 로고
    • Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas
    • Brunner, T. et al. (1995) Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature, 373, 441-444.
    • (1995) Nature , vol.373 , pp. 441-444
    • Brunner, T.1
  • 8
    • 0027268697 scopus 로고
    • Increased cyclin a and decreased cyclin D levels in adenovirus 5 transformed rodent cell lines
    • Buchou, T., Kranenburg, O., van Dam, H., Roelen, D., Zantema, A., Hall, F.L. and van der Eb, A.J. (1993) Increased cyclin A and decreased cyclin D levels in adenovirus 5 transformed rodent cell lines. Oncogene, 8, 1765-1773.
    • (1993) Oncogene , vol.8 , pp. 1765-1773
    • Buchou, T.1    Kranenburg, O.2    Van Dam, H.3    Roelen, D.4    Zantema, A.5    Hall, F.L.6    Van Der Eb, A.J.7
  • 10
    • 0027251720 scopus 로고
    • Wild-type p53 mediates apoptosis by E1A which is inhibited by E1B
    • Debbas, M. and White, E. (1993) Wild-type p53 mediates apoptosis by E1A which is inhibited by E1B. Genes Dev., 7, 546-554.
    • (1993) Genes Dev. , vol.7 , pp. 546-554
    • Debbas, M.1    White, E.2
  • 11
    • 0020004193 scopus 로고
    • The plasma membrane as a regulatory site in growth and differentiation of neuroblastoma cells
    • de Laat, S.W. and van der Saag, P.T. (1982) The plasma membrane as a regulatory site in growth and differentiation of neuroblastoma cells. Int. Rev Cytol., 74, 1-54.
    • (1982) Int. Rev Cytol. , vol.74 , pp. 1-54
    • De Laat, S.W.1    Van Der Saag, P.T.2
  • 13
    • 0027946686 scopus 로고
    • Altered gene expression in neurons during programmed cell death: Identification of c-jun as necessary for neuronal apoptosis
    • Estus, S., Zaks, W.J., Freeman, R.S., Gruda, M., Bravo, R. and Johnson, E.M., Jr (1994) Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis. J. Cell Biol., 6, 1717-1727.
    • (1994) J. Cell Biol. , vol.6 , pp. 1717-1727
    • Estus, S.1    Zaks, W.J.2    Freeman, R.S.3    Gruda, M.4    Bravo, R.5    Johnson Jr., E.M.6
  • 15
    • 0027229136 scopus 로고
    • Functional interactions of the retinoblastoma protein with mammalian D-type cyclins
    • Ewen, M.E., Sluss, H.K., Sherr, C.J., Matsushime, H., Kato, J.-Y. and Livingston, D.M. (1993) Functional interactions of the retinoblastoma protein with mammalian D-type cyclins. Cell, 73, 487-497.
    • (1993) Cell , vol.73 , pp. 487-497
    • Ewen, M.E.1    Sluss, H.K.2    Sherr, C.J.3    Matsushime, H.4    Kato, J.-Y.5    Livingston, D.M.6
  • 16
    • 0028607141 scopus 로고
    • Proliferative inhibition by dominant negative Ras rescues naive and neuronally differentiated PC12 cells from apoptotic death
    • Ferrari, G. and Greene, L. (1994) Proliferative inhibition by dominant negative Ras rescues naive and neuronally differentiated PC12 cells from apoptotic death. EMBO J., 13, 5922-5928.
    • (1994) EMBO J. , vol.13 , pp. 5922-5928
    • Ferrari, G.1    Greene, L.2
  • 18
    • 0028324310 scopus 로고
    • Analysis of cell cycle-related gene expression in post-mitotic neurons: Selective induction of cyclin D1 during programmed cell death
    • Freeman, R.S., Estus, S. and Johnson, E.M., Jr (1994) Analysis of cell cycle-related gene expression in post-mitotic neurons: selective induction of cyclin D1 during programmed cell death. Neuron, 12, 343-355.
    • (1994) Neuron , vol.12 , pp. 343-355
    • Freeman, R.S.1    Estus, S.2    Johnson Jr., E.M.3
  • 20
    • 0026058874 scopus 로고
    • The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle
    • Goodrich, D.W., Wang, N.P, Qian, Y.-W., Lee, E.Y.-H.P. and Lee, W.-H. (1991) The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle. Cell, 67, 293-302.
    • (1991) Cell , vol.67 , pp. 293-302
    • Goodrich, D.W.1    Wang, N.P.2    Qian, Y.-W.3    Lee, E.Y.-H.P.4    Lee, W.-H.5
  • 23
    • 0027178335 scopus 로고
    • Cell death and the cell cycle: A relationship between transformation and neurodegeneration?
    • Heintz, N. (1993) Cell death and the cell cycle: a relationship between transformation and neurodegeneration? Trends Biochem. Sci., 18, 157-159.
    • (1993) Trends Biochem. Sci. , vol.18 , pp. 157-159
    • Heintz, N.1
  • 24
    • 0028472896 scopus 로고
    • Inducible regulatory elements in the human cyclin D1 promoter
    • Herber, B., Truss, M., Beato, M. and Müller, R. (1994) Inducible regulatory elements in the human cyclin D1 promoter. Oncogene, 9, 1295-1304.
    • (1994) Oncogene , vol.9 , pp. 1295-1304
    • Herber, B.1    Truss, M.2    Beato, M.3    Müller, R.4
  • 26
    • 0028918388 scopus 로고
    • Novel INK4 proteins p19 and p18 are specific inhibitors of the cyclin D-dependent kinases cdk4 and cdk6
    • Hirai, H., Roussel, M., Kato, J.-Y., Ashmun, R.A. and Sherr, C.J. (1995) Novel INK4 proteins p19 and p18 are specific inhibitors of the cyclin D-dependent kinases cdk4 and cdk6. Mol. Cell. Biol., 15, 2672-2681
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2672-2681
    • Hirai, H.1    Roussel, M.2    Kato, J.-Y.3    Ashmun, R.A.4    Sherr, C.J.5
  • 28
    • 0018970029 scopus 로고
    • Partial transformation of primary rat cells by the leftmost 4.5% fragment of adenovirus 5 DNA
    • Houweling, A., van den Elsen, P.J. and van der Eb, A.J. (1980) Partial transformation of primary rat cells by the leftmost 4.5% fragment of adenovirus 5 DNA. Virology, 105, 537-550.
    • (1980) Virology , vol.105 , pp. 537-550
    • Houweling, A.1    Van Den Elsen, P.J.2    Van Der Eb, A.J.3
  • 30
    • 0028587054 scopus 로고
    • Growth factor-like effects of lysophosphatidic acid, a novel lipid mediator
    • Jalink, K., Hordijk, P. and Moolenaar, W. (1994) Growth factor-like effects of lysophosphatidic acid, a novel lipid mediator. Biochim. Biophys. Acta, 1198, 185-196.
    • (1994) Biochim. Biophys. Acta , vol.1198 , pp. 185-196
    • Jalink, K.1    Hordijk, P.2    Moolenaar, W.3
  • 31
    • 0027494864 scopus 로고
    • Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control cell cycle progression and gene expression
    • Jiang, W., Kahn, S.M., Zhou, P., Zhang, Y.-J., Cacace, A.M., Infante, A.S., Doi, S., Santella, R.M. and Weinstein, I.B. (1993) Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control cell cycle progression and gene expression. Oncogene, 8, 3447-3457.
    • (1993) Oncogene , vol.8 , pp. 3447-3457
    • Jiang, W.1    Kahn, S.M.2    Zhou, P.3    Zhang, Y.-J.4    Cacace, A.M.5    Infante, A.S.6    Doi, S.7    Santella, R.M.8    Weinstein, I.B.9
  • 32
    • 0027288908 scopus 로고
    • Direct binding of cyclin D to the retinoblastoma gene product and pRb phosphorylation by the cyclin D-dependent kinase cdk4
    • Kato, J.-Y., Matsushime, H , Hiebert, S., Ewen, M.E. and Sherr, C.J. (1993) Direct binding of cyclin D to the retinoblastoma gene product and pRb phosphorylation by the cyclin D-dependent kinase cdk4. Genes Dev., 7, 331-342.
    • (1993) Genes Dev. , vol.7 , pp. 331-342
    • Kato, J.-Y.1    Matsushime, H.2    Hiebert, S.3    Ewen, M.E.4    Sherr, C.J.5
  • 33
    • 0028981325 scopus 로고
    • Differentiation of P19 EC cells leads to differential modulation of cyclin-dependent kinase activities and to changes in the cell cycle profile
    • Kranenburg, O., de Groot, R.P., van der Eb, A.J. and Zantema, A (1995) Differentiation of P19 EC cells leads to differential modulation of cyclin-dependent kinase activities and to changes in the cell cycle profile. Oncogene, 10, 87-95.
    • (1995) Oncogene , vol.10 , pp. 87-95
    • Kranenburg, O.1    De Groot, R.P.2    Van Der Eb, A.J.3    Zantema, A.4
  • 34
    • 0026744563 scopus 로고
    • Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
    • Lee, E.Y.-H.P., Chang, C.-Y., Hu, N., Wang, J., Lai, C.-C., Herrup, K., Lee, W.-H. and Bradley, A. (1992) Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature, 359, 288-294.
    • (1992) Nature , vol.359 , pp. 288-294
    • Lee, E.Y.-H.P.1    Chang, C.-Y.2    Hu, N.3    Wang, J.4    Lai, C.-C.5    Herrup, K.6    Lee, W.-H.7    Bradley, A.8
  • 35
    • 0028131540 scopus 로고
    • Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation
    • Lee, E.Y.-H.P., Hu, N., Yuan, S.-S.F. Cox, L.A., Bradley, A., Lee, W.-H. and Herrup, K. (1994) Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev., 8, 2008-2021
    • (1994) Genes Dev. , vol.8 , pp. 2008-2021
    • Lee, E.Y.-H.P.1    Hu, N.2    Yuan, S.-S.F.3    Cox, L.A.4    Bradley, A.5    Lee, W.-H.6    Herrup, K.7
  • 36
    • 0028049592 scopus 로고
    • Cyclin D1/bcll cooperates with myc genes in the generation of B cell lymphoma in transgenic mice
    • Lovec, H , Grzeschiczek, A , Kowalski, M B. and Möroy, T. (1994a) Cyclin D1/bcll cooperates with myc genes in the generation of B cell lymphoma in transgenic mice. EMBO J., 13, 3487-3495.
    • (1994) EMBO J. , vol.13 , pp. 3487-3495
    • Lovec, H.1    Grzeschiczek, A.2    Kowalski, M.B.3    Möroy, T.4
  • 37
    • 0027976222 scopus 로고
    • Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: Link between cell cycle control and malignant transformation
    • Lovec, H., Sewing, A., Lucibello, F.C., Müller, R and Möröy, T. (1994b) Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: link between cell cycle control and malignant transformation. Oncogene, 9, 323-326.
    • (1994) Oncogene , vol.9 , pp. 323-326
    • Lovec, H.1    Sewing, A.2    Lucibello, F.C.3    Müller, R.4    Möröy, T.5
  • 38
    • 0027262606 scopus 로고
    • Stabilization of the p53 tumor suppressor is induced by adenovirus E1A and accompanies apoptosis
    • Lowe, S.W. and Ruley, H.E. (1993) Stabilization of the p53 tumor suppressor is induced by adenovirus E1A and accompanies apoptosis. Genes Dev., 7, 535-545.
    • (1993) Genes Dev. , vol.7 , pp. 535-545
    • Lowe, S.W.1    Ruley, H.E.2
  • 39
    • 0028279059 scopus 로고
    • DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1
    • Lukas, J., Müller, H., Bartkova, J., Spitkovsky, D., Kerljuff, A.A , Junsen-Durr, P., Strauss, M. and Bartek, J. (1994) DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1. J. Cell Biol. 125, 625-638.
    • (1994) J. Cell Biol. , vol.125 , pp. 625-638
    • Lukas, J.1    Müller, H.2    Bartkova, J.3    Spitkovsky, D.4    Kerljuff, A.A.5    Junsen-Durr, P.6    Strauss, M.7    Bartek, J.8
  • 40
    • 0028925360 scopus 로고
    • Cyclin D1 is dispensable for G1 control in retinoblastoma deficient cells independently of cdk4 activity
    • Lukas, J., Bartkova, J., Rohde, M., Strauss, M. and Bartek, J. (1995a) Cyclin D1 is dispensable for G1 control in retinoblastoma deficient cells independently of cdk4 activity. Mol. Cell. Biol., 15, 2600-2611
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2600-2611
    • Lukas, J.1    Bartkova, J.2    Rohde, M.3    Strauss, M.4    Bartek, J.5
  • 42
    • 0025607921 scopus 로고
    • New light on Myc and Myb I. Myc
    • Luscher, B. and Eisenman, R.N (1990) New light on Myc and Myb I. Myc. Genes Dev., 4, 2025-2035.
    • (1990) Genes Dev. , vol.4 , pp. 2025-2035
    • Luscher, B.1    Eisenman, R.N.2
  • 43
    • 0023851503 scopus 로고
    • Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation
    • Martin, D.P., Schmidt, R.E , DiStefano, P.S., Lowry, O.H., Carter, J.G and Johnson, E.M ,Jr (1988) Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation. J. Cell Biol., 106, 829-844.
    • (1988) J. Cell Biol. , vol.106 , pp. 829-844
    • Martin, D.P.1    Schmidt, R.E.2    DiStefano, P.S.3    Lowry, O.H.4    Carter, J.G.5    Johnson Jr., E.M.6
  • 44
    • 0028982748 scopus 로고
    • Viral proteins E1B19K and p35 protect sympathetic neurons from cell death induced by NGF deprivation
    • Maninou, I., Fernandez, P.-A., Missoten, M., White, E., Allet, B., Sadoul, R. and Martinou, J.-C. (1995) Viral proteins E1B19K and p35 protect sympathetic neurons from cell death induced by NGF deprivation J. Cell Biol., 128, 201-208.
    • (1995) J. Cell Biol. , vol.128 , pp. 201-208
    • Maninou, I.1    Fernandez, P.-A.2    Missoten, M.3    White, E.4    Allet, B.5    Sadoul, R.6    Martinou, J.-C.7
  • 47
    • 0028181760 scopus 로고
    • Identification of G1 kinase activity for cdk6, a novel cyclin D partner
    • Meyerson, M. and Harlow, E. (1994) Identification of G1 kinase activity for cdk6, a novel cyclin D partner. Mol. Cell. Biol., 14, 2077-2086
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 2077-2086
    • Meyerson, M.1    Harlow, E.2
  • 48
    • 0027934570 scopus 로고
    • p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
    • Morgenbesser, S., Williams, B.O., Jacks, T. and DePinho, R.A. (1994) p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature, 371, 72-74.
    • (1994) Nature , vol.371 , pp. 72-74
    • Morgenbesser, S.1    Williams, B.O.2    Jacks, T.3    DePinho, R.A.4
  • 49
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim, R.W. (1991) Cell death during development of the nervous system. Annu. Rev. Neurosci., 14, 453-501.
    • (1991) Annu. Rev. Neurosci. , vol.14 , pp. 453-501
    • Oppenheim, R.W.1
  • 50
    • 0028456527 scopus 로고
    • Relationship of p53 to the control of apoptotic cell death
    • Oren, M. (1994) Relationship of p53 to the control of apoptotic cell death. Semin. Cancer Biol., 5, 221-227.
    • (1994) Semin. Cancer Biol. , vol.5 , pp. 221-227
    • Oren, M.1
  • 51
    • 0028129498 scopus 로고
    • Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts
    • Pagano, M., Theodoras, A.M., Tam, S.W. and Draetta, G. (1994) Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts. Genes Dev., 8, 1627-1639.
    • (1994) Genes Dev. , vol.8 , pp. 1627-1639
    • Pagano, M.1    Theodoras, A.M.2    Tam, S.W.3    Draetta, G.4
  • 53
    • 0028173667 scopus 로고
    • Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system
    • Resnitzky, D , Gossen, M., Bujard, H. and Reed, S. (1994) Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system. Mol. Cell. Biol., 14, 1669-1679.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1669-1679
    • Resnitzky, D.1    Gossen, M.2    Bujard, H.3    Reed, S.4
  • 54
    • 0027769876 scopus 로고
    • A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/cdk4
    • Serrano, M., Hannon, G. and Beach, D. (1993) A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/cdk4. Nature, 366, 704-707.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.2    Beach, D.3
  • 55
    • 0028171292 scopus 로고
    • G1 phase progression: Cycling on cue
    • Sherr, C.J. (1994) G1 phase progression: cycling on cue. Cell, 79, 551-555.
    • (1994) Cell , vol.79 , pp. 551-555
    • Sherr, C.J.1
  • 56
    • 0028036487 scopus 로고
    • Methods for the detection of apoptosis
    • Sgonc, R. and Wick, G. (1994) Methods for the detection of apoptosis. Int. Arch. Allergy Immunol., 105, 327-332
    • (1994) Int. Arch. Allergy Immunol. , vol.105 , pp. 327-332
    • Sgonc, R.1    Wick, G.2
  • 58
    • 0028360766 scopus 로고
    • Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation
    • Singh, P., Wong, S.H. and Hong, W. (1994) Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation. EMBO J , 13, 3329-3338.
    • (1994) EMBO J , vol.13 , pp. 3329-3338
    • Singh, P.1    Wong, S.H.2    Hong, W.3
  • 59
    • 0029155019 scopus 로고
    • Altered phosphorylation and oligomerization of p53 in adenovirus type 12-transformed cells
    • Steegenga, W., Shvarts, A., van Laar, T., van der Eb, A.J. and Jochemsen, A.G. (1995) Altered phosphorylation and oligomerization of p53 in adenovirus type 12-transformed cells. Oncogene, 11, 49-57.
    • (1995) Oncogene , vol.11 , pp. 49-57
    • Steegenga, W.1    Shvarts, A.2    Van Laar, T.3    Van Der Eb, A.J.4    Jochemsen, A.G.5
  • 60
    • 0027742184 scopus 로고
    • Distinct roles for cyclin-dependent kinases in cell cycle control
    • van den Heuvel, S.J.L. and Harlow, E. (1993) Distinct roles for cyclin-dependent kinases in cell cycle control. Science, 262, 2050-2054.
    • (1993) Science , vol.262 , pp. 2050-2054
    • Van Den Heuvel, S.J.L.1    Harlow, E.2
  • 61
    • 0027204173 scopus 로고
    • Large E1B proteins of adenovirus types 5 and 12 have different effects on p53 and distinct roles in cell transformation
    • van den Heuvel, S.J.L , van Laar, T., The, I. and van der Eb, A.J. (1993) Large E1B proteins of adenovirus types 5 and 12 have different effects on p53 and distinct roles in cell transformation. J. Virol., 67, 5226-5234.
    • (1993) J. Virol. , vol.67 , pp. 5226-5234
    • Van Den Heuvel, S.J.L.1    Van Laar, T.2    The, I.3    Van Der Eb, A.J.4
  • 62
    • 0018815076 scopus 로고
    • Assay of transforming activity of tumor virus DNA
    • van der Eb, A.J. and Graham, F. (1980) Assay of transforming activity of tumor virus DNA. Methods Enzymol., 65, 826-839.
    • (1980) Methods Enzymol. , vol.65 , pp. 826-839
    • Van Der Eb, A.J.1    Graham, F.2
  • 63
    • 0028243879 scopus 로고
    • Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice
    • Wang, T.C, Cardiff, R.D , Zukerberg, L., Lees, E., Arnold, A. and Schmidt, E.V. (1994) Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice. Nature, 369, 669-671.
    • (1994) Nature , vol.369 , pp. 669-671
    • Wang, T.C.1    Cardiff, R.D.2    Zukerberg, L.3    Lees, E.4    Arnold, A.5    Schmidt, E.V.6
  • 64
    • 0028222124 scopus 로고
    • p53 and E2F1 cooperate to mediate apoptosis
    • Wu, X. and Levine, A (1994) p53 and E2F1 cooperate to mediate apoptosis. Proc. Natl Acad. Sci. USA, 91, 3602-3606.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 3602-3606
    • Wu, X.1    Levine, A.2
  • 65
    • 0028945789 scopus 로고
    • Multiple members of the E2F transcription factor family are the products of oncogenes
    • Xu, G., Livingston, D.M. and Krek, W. (1995) Multiple members of the E2F transcription factor family are the products of oncogenes. Proc Natl Acad. Sci. USA, 92, 1357-1361.
    • (1995) Proc Natl Acad. Sci. USA , vol.92 , pp. 1357-1361
    • Xu, G.1    Livingston, D.M.2    Krek, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.