메뉴 건너뛰기




Volumn 2, Issue 12, 1996, Pages 2015-2022

bcl-2 and p53 expression in resectable pancreatic adenocarcinomas: Association with clinical outcome

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; PROTEIN BCL 2; PROTEIN P53;

EID: 0030443653     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (55)

References (47)
  • 2
    • 0027733796 scopus 로고
    • K-ras oncogene activation in adenocarcinoma of the human pancreas A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization
    • Hruban, R. H., van Mansfeld, A D. M., Offerhaus, G. J., van Weering, D. H J., Allison, D. C., Goodman, S. N., Kensler, T. W., Bose, K. K , Cameron, J. L., and Bos, J. L. K-ras oncogene activation in adenocarcinoma of the human pancreas A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization. Am. J. Pathol., 143: 545-554, 1993.
    • (1993) Am. J. Pathol. , vol.143 , pp. 545-554
    • Hruban, R.H.1    Van Mansfeld, A.D.M.2    Offerhaus, G.J.3    Van Weering, D.H.J.4    Allison, D.C.5    Goodman, S.N.6    Kensler, T.W.7    Bose, K.K.8    Cameron, J.L.9    Bos, J.L.10
  • 3
    • 0024292722 scopus 로고
    • Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
    • Almoguerra, C., Shibata, D., Forrester, K , Martin, J., Arnheim, N., and Perucho, M Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell, 53: 549-554, 1988.
    • (1988) Cell , vol.53 , pp. 549-554
    • Almoguerra, C.1    Shibata, D.2    Forrester, K.3    Martin, J.4    Arnheim, N.5    Perucho, M.6
  • 4
    • 0028268635 scopus 로고
    • K-ras and p53 gene mutations in pancreatic cancer: Ductal and nonductal tumors progress through different genetic lesions
    • Pellegata, N. S., Sessa, F., Renault, B., Bonato, M., Leone, B. E., Solcia, E., and Ranzani, G. N. K-ras and p53 gene mutations in pancreatic cancer: ductal and nonductal tumors progress through different genetic lesions. Cancer Res., 54: 1556-1560, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 1556-1560
    • Pellegata, N.S.1    Sessa, F.2    Renault, B.3    Bonato, M.4    Leone, B.E.5    Solcia, E.6    Ranzani, G.N.7
  • 5
    • 0028308492 scopus 로고
    • p53 mutations in pancreatic carcinomas and evidence of common involvement of homocopolymer tracts in DNA microdeletions
    • Redston, M. S., Caldas, C., Seymour, A. B., Hruban, R. H., daCosta, L. T., Yeo, C. J., and Kern, S. E. p53 mutations in pancreatic carcinomas and evidence of common involvement of homocopolymer tracts in DNA microdeletions. Cancer Res , 54: 3025-3033, 1994.
    • (1994) Cancer Res , vol.54 , pp. 3025-3033
    • Redston, M.S.1    Caldas, C.2    Seymour, A.B.3    Hruban, R.H.4    DaCosta, L.T.5    Yeo, C.J.6    Kern, S.E.7
  • 11
    • 0028025563 scopus 로고
    • Apoptosis in cancer therapy: Crossing the threshold
    • Fisher, D. E. Apoptosis in cancer therapy: crossing the threshold. Cell. 78: 539-542, 1994.
    • (1994) Cell , vol.78 , pp. 539-542
    • Fisher, D.E.1
  • 12
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed, J. C. Bcl-2 and the regulation of programmed cell death. J. Cell Biol., 124: 1-6, 1994.
    • (1994) J. Cell Biol. , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 13
    • 0026781986 scopus 로고
    • bcl-2 gene transfer increases relative resistance of S49 1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs
    • Miyashita, T., and Reed, J bcl-2 gene transfer increases relative resistance of S49 1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs. Cancer Res., 52: 75407-5411, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 75407-75411
    • Miyashita, T.1    Reed, J.2
  • 14
    • 0025835716 scopus 로고
    • Bcl-2 protein is topographically restricted to tissue characterized by apoptotic cell death
    • Hockenberry, D., Zutter, M., Hickey, W., Nahm, M., and Korsmeyer, S. J. Bcl-2 protein is topographically restricted to tissue characterized by apoptotic cell death. Proc. Natl. Acad. Sci. USA, 85: 6961-6965, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 6961-6965
    • Hockenberry, D.1    Zutter, M.2    Hickey, W.3    Nahm, M.4    Korsmeyer, S.J.5
  • 15
    • 0028896159 scopus 로고
    • bcl-2 and p53 oncoprotein expression during colorectal tumorigenesis
    • Sinicrope, F. A., Ruan, S., Cleary, K. R., Lee, J. J., and Levin, B. bcl-2 and p53 oncoprotein expression during colorectal tumorigenesis. Cancer Res., 55: 237-241, 1995
    • (1995) Cancer Res. , vol.55 , pp. 237-241
    • Sinicrope, F.A.1    Ruan, S.2    Cleary, K.R.3    Lee, J.J.4    Levin, B.5
  • 16
    • 0028109983 scopus 로고
    • bcl-2 expression in human colorectal adenomas and carcinomas
    • Hague, A., Moorghen, M., Hicks, D., Chapman, M., and Paraskeva, C. bcl-2 expression in human colorectal adenomas and carcinomas. Oncogene. 9: 3367-3370, 1994.
    • (1994) Oncogene , vol.9 , pp. 3367-3370
    • Hague, A.1    Moorghen, M.2    Hicks, D.3    Chapman, M.4    Paraskeva, C.5
  • 17
    • 0028865264 scopus 로고
    • Prognostic value of bcl-2 oncoprotein expression in Stage II colon carcinoma
    • Sinicrope, F. A., Hart, J., Michelassi, F. M., and Lee, J. J. Prognostic value of bcl-2 oncoprotein expression in Stage II colon carcinoma. Clin. Cancer Res., 1: 1103-1110, 1995.
    • (1995) Clin. Cancer Res. , vol.1 , pp. 1103-1110
    • Sinicrope, F.A.1    Hart, J.2    Michelassi, F.M.3    Lee, J.J.4
  • 18
    • 0028871326 scopus 로고
    • Immunohistochemically detectable bcl-2 expression in colorectal carcinoma: Correlation with tumour stage and patient survival
    • Öfner, D., Riehemann, K., Maier, H., Reidmann, B , Nehoda, H., Totsch, M., Bocker, W., Jasani, B., and Schmid, K. W. Immunohistochemically detectable bcl-2 expression in colorectal carcinoma: correlation with tumour stage and patient survival. Br. J. Cancer, 72: 981-985, 1995.
    • (1995) Br. J. Cancer , vol.72 , pp. 981-985
    • Öfner, D.1    Riehemann, K.2    Maier, H.3    Reidmann, B.4    Nehoda, H.5    Totsch, M.6    Bocker, W.7    Jasani, B.8    Schmid, K.W.9
  • 19
    • 0030024253 scopus 로고    scopus 로고
    • Apoptosis and immunohistochemical bcl-2 expression in colorectal adenomas and carcinomas: Aspects of carcinogenesis and prognostic significance
    • Phila.
    • Baretton, G. B., Diebold, J., Christoforis, G., Vogt, M., Müller, C., Dopfer, K., Schneiderbanger, K., Schmidt, M., and Lohrs, U. Apoptosis and immunohistochemical bcl-2 expression in colorectal adenomas and carcinomas: aspects of carcinogenesis and prognostic significance. Cancer (Phila.), 77: 255-264, 1996.
    • (1996) Cancer , vol.77 , pp. 255-264
    • Baretton, G.B.1    Diebold, J.2    Christoforis, G.3    Vogt, M.4    Müller, C.5    Dopfer, K.6    Schneiderbanger, K.7    Schmidt, M.8    Lohrs, U.9
  • 21
    • 0027944957 scopus 로고
    • Bcl-2 protein expression and long-term survival in breast cancer
    • Joensuu, H., Pylkkanen, L., and Toikkanen, S. Bcl-2 protein expression and long-term survival in breast cancer. Am. J. Pathol., 145: 1191-1198, 1994.
    • (1994) Am. J. Pathol. , vol.145 , pp. 1191-1198
    • Joensuu, H.1    Pylkkanen, L.2    Toikkanen, S.3
  • 25
    • 0026656853 scopus 로고
    • Wild-type p53 is a cell cycle checkpoint determinant following irradiation
    • Kuerbitz, S. J., Plunkett, B. S., Walsh, W. V., and Kastan, M. B. Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc. Natl. Acad. Sci. USA, 89: 7491-7495, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7491-7495
    • Kuerbitz, S.J.1    Plunkett, B.S.2    Walsh, W.V.3    Kastan, M.B.4
  • 26
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach, E., Resnitzky, D., Lotem, J., Sachs, L., Kimchi, A., and Oren, M. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature (Lond.), 352: 345-347, 1991.
    • (1991) Nature (Lond.) , vol.352 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6
  • 28
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt, M. S., Bennett, W P , Hollstein, M., and Harris, C. C. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res., 54: 4855-4878, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 31
    • 0023262033 scopus 로고
    • Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer
    • Phila.
    • Gastrointestinal Tumor Study Group. Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer. Cancer (Phila.), 59: 2006-2010, 1987.
    • (1987) Cancer , vol.59 , pp. 2006-2010
  • 39
    • 0026507159 scopus 로고
    • High frequency of p53 gene alterations associated with protein overexpression in human squamous cell carcinoma of the larynx
    • Maestro, R., Dolcetti, R., Gasparotto, D., Doglioni, C., Pelucchis, S., Barzan, L., Grandi, E., and Boiocchi, M. High frequency of p53 gene alterations associated with protein overexpression in human squamous cell carcinoma of the larynx. Oncogene, 7: 1159-1166, 1992.
    • (1992) Oncogene , vol.7 , pp. 1159-1166
    • Maestro, R.1    Dolcetti, R.2    Gasparotto, D.3    Doglioni, C.4    Pelucchis, S.5    Barzan, L.6    Grandi, E.7    Boiocchi, M.8
  • 40
    • 0026649648 scopus 로고
    • The indin-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • Momand, J., Zambetti, G. P., Olsen, D. C., George, D., and Levine, A. J. The indin-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell, 69: 1237-1245, 1992.
    • (1992) Cell , vol.69 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olsen, D.C.3    George, D.4    Levine, A.J.5
  • 41
    • 0028222955 scopus 로고
    • Bcl-2 blocks p53-dependent apoptosis
    • Chiou, S-K., Rao, L., and White, E Bcl-2 blocks p53-dependent apoptosis. Mol. Cell Biol., 14: 2556-2563, 1994.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 2556-2563
    • Chiou, S.-K.1    Rao, L.2    White, E.3
  • 42
    • 0029868112 scopus 로고    scopus 로고
    • The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death promoting Bax protein
    • Han, J., Sabbatini, P., Perez, D., Rao, L., Modha, D., and White, E. The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death promoting Bax protein. Genes Dev., 10: 461-477, 1996.
    • (1996) Genes Dev. , vol.10 , pp. 461-477
    • Han, J.1    Sabbatini, P.2    Perez, D.3    Rao, L.4    Modha, D.5    White, E.6
  • 44
    • 15844397398 scopus 로고    scopus 로고
    • Diminished cell proliferation associated with death-protective activity of bcl-2
    • Borner, C. Diminished cell proliferation associated with death-protective activity of bcl-2. J Biol. Chem., 22: 12695-12698, 1996.
    • (1996) J Biol. Chem. , vol.22 , pp. 12695-12698
    • Borner, C.1
  • 45
    • 0029895458 scopus 로고    scopus 로고
    • Deletion of nonconserved region of bcl-2 confers a novel gain of function: Suppression of apoptosis with concomitant cell proliferation
    • Uhlmann, E. J , D'Sa-Eipper, C., Subramanian, T., Wagner, A. J., Hay, N., and Chinnadurai, G. Deletion of nonconserved region of bcl-2 confers a novel gain of function: suppression of apoptosis with concomitant cell proliferation. Cancer Res., 56. 2506-2509, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 2506-2509
    • Uhlmann, E.J.1    D'Sa-Eipper, C.2    Subramanian, T.3    Wagner, A.J.4    Hay, N.5    Chinnadurai, G.6
  • 46
    • 0029899181 scopus 로고    scopus 로고
    • Molecular thanatopsis: A discourse on the bcl-2 family and cell death
    • Korsmeyer, S. J Molecular thanatopsis: a discourse on the bcl-2 family and cell death Blood, 88: 386-401, 1996.
    • (1996) Blood , vol.88 , pp. 386-401
    • Korsmeyer, S.J.1
  • 47
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homologue, Bax, that accelerates programmed cell death
    • Oltvai, Z., Milliman, C., and Korsmeyer, S. J. Bcl-2 heterodimerizes in vivo with a conserved homologue, Bax, that accelerates programmed cell death. Cell, 74: 609-619, 1993.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.1    Milliman, C.2    Korsmeyer, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.