메뉴 건너뛰기




Volumn 22, Issue 6, 2004, Pages 908-924

Fas ligand as a tool for immunosuppression and generation of immune tolerance

Author keywords

Allogeneic; Dendritic cells; Fas ligand(FasL); gld; Immune privilege; lpr; Tolerance

Indexed keywords

FAS LIGAND;

EID: 8644250720     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.22-6-908     Document Type: Short Survey
Times cited : (52)

References (205)
  • 1
    • 0033593572 scopus 로고    scopus 로고
    • Cell death in development
    • Vaux DL, Korsmeyer SJ. Cell death in development. Cell 1999;96:245-254.
    • (1999) Cell , vol.96 , pp. 245-254
    • Vaux, D.L.1    Korsmeyer, S.J.2
  • 2
    • 0034641980 scopus 로고    scopus 로고
    • Apoptosis in development
    • Meier P, Finch A, Evan G. Apoptosis in development. Nature 2000;407:796-801.
    • (2000) Nature , vol.407 , pp. 796-801
    • Meier, P.1    Finch, A.2    Evan, G.3
  • 3
    • 0034574306 scopus 로고    scopus 로고
    • The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity
    • Siegel RM, Chan FK, Chun HJ et al. The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity. Nat Immunol 2000;1:469-474.
    • (2000) Nat Immunol , vol.1 , pp. 469-474
    • Siegel, R.M.1    Chan, F.K.2    Chun, H.J.3
  • 4
    • 0038393112 scopus 로고    scopus 로고
    • Apoptosis in the development and maintenance of the immune system
    • Opferman JT, Korsmeyer SJ. Apoptosis in the development and maintenance of the immune system. Nat Immunol 2003;4:410-415.
    • (2003) Nat Immunol , vol.4 , pp. 410-415
    • Opferman, J.T.1    Korsmeyer, S.J.2
  • 5
    • 0026568919 scopus 로고
    • Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
    • Watanabe-Fukunaga R, Brannan CI, Copeland NG et al. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 1992;356:314-317.
    • (1992) Nature , vol.356 , pp. 314-317
    • Watanabe-Fukunaga, R.1    Brannan, C.I.2    Copeland, N.G.3
  • 6
    • 0029124165 scopus 로고
    • Characterization of the non-functional Fas ligand of gld mice
    • Hahne M, Peitsch MC, Irmler M et al. Characterization of the non-functional Fas ligand of gld mice. Int Immunol 1995;7:1381-1386.
    • (1995) Int Immunol , vol.7 , pp. 1381-1386
    • Hahne, M.1    Peitsch, M.C.2    Irmler, M.3
  • 7
    • 0029737324 scopus 로고    scopus 로고
    • Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease
    • Wu J, Wilson J, He J et al. Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease. J Clin Invest 1996;98:1107-1113.
    • (1996) J Clin Invest , vol.98 , pp. 1107-1113
    • Wu, J.1    Wilson, J.2    He, J.3
  • 8
    • 0031746760 scopus 로고    scopus 로고
    • Human autoimmune lymphoproliferative syndrome, a defect in the apoptosis-inducing Fas receptor: A lesson from the mouse model
    • Nagata S. Human autoimmune lymphoproliferative syndrome, a defect in the apoptosis-inducing Fas receptor: a lesson from the mouse model. J Hum Genet 1998;43:2-8.
    • (1998) J Hum Genet , vol.43 , pp. 2-8
    • Nagata, S.1
  • 10
    • 0029097729 scopus 로고
    • Fas (CD95) participates in peripheral T cell deletion and associated apoptosis in vivo
    • Mogil RJ, Radvanyi L, Gonzalez-Quintial R et al. Fas (CD95) participates in peripheral T cell deletion and associated apoptosis in vivo. Int Immunol 1995;7:1451-1458.
    • (1995) Int Immunol , vol.7 , pp. 1451-1458
    • Mogil, R.J.1    Radvanyi, L.2    Gonzalez-Quintial, R.3
  • 11
    • 0030060153 scopus 로고    scopus 로고
    • Peripheral T cells undergoing superantigen-induced apoptosis in vivo express B220 and upregulate Fas and Fas ligand
    • Renno T, Hahne M, Tschopp J et al. Peripheral T cells undergoing superantigen-induced apoptosis in vivo express B220 and upregulate Fas and Fas ligand. J Exp Med 1996;183:431-437.
    • (1996) J Exp Med , vol.183 , pp. 431-437
    • Renno, T.1    Hahne, M.2    Tschopp, J.3
  • 12
    • 0029944667 scopus 로고    scopus 로고
    • Enhanced and accelerated lymphoproliferation in Fas-null mice
    • Adachi M, Suematsu S, Suda T et al. Enhanced and accelerated lymphoproliferation in Fas-null mice. Proc Natl Acad Sci USA 1996;93:2131-2136.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2131-2136
    • Adachi, M.1    Suematsu, S.2    Suda, T.3
  • 13
    • 17944394558 scopus 로고    scopus 로고
    • Inducible nonlymphoid expression of Fas ligand is responsible for superantigen-induced peripheral deletion of T cells
    • Bonfoco E, Stuart PM, Brunner T et al. Inducible nonlymphoid expression of Fas ligand is responsible for superantigen-induced peripheral deletion of T cells. Immunity 1998;9:711-720.
    • (1998) Immunity , vol.9 , pp. 711-720
    • Bonfoco, E.1    Stuart, P.M.2    Brunner, T.3
  • 14
    • 0037058931 scopus 로고    scopus 로고
    • Nonlymphoid Fas ligand in peptide-induced peripheral lymphocyte deletion
    • Pinkoski MJ, Droin NM, Lin T et al. Nonlymphoid Fas ligand in peptide-induced peripheral lymphocyte deletion. Proc Natl Acad Sci U S A 2002;99:16174-16179.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 16174-16179
    • Pinkoski, M.J.1    Droin, N.M.2    Lin, T.3
  • 15
    • 0038171458 scopus 로고    scopus 로고
    • Activation-induced cell death in T cells
    • Green DR, Droin N, Pinkoski M. Activation-induced cell death in T cells. Immunol Rev 2003;193:70-81.
    • (2003) Immunol Rev , vol.193 , pp. 70-81
    • Green, D.R.1    Droin, N.2    Pinkoski, M.3
  • 17
    • 0028486130 scopus 로고
    • Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes
    • Kojima H, Shinohara N, Hanaoka S et al. Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes. Immunity 1994;:357-364.
    • (1994) Immunity , pp. 357-364
    • Kojima, H.1    Shinohara, N.2    Hanaoka, S.3
  • 18
    • 0028111580 scopus 로고
    • The role of the Fas lytic pathway in a perforin-less CTL hybridoma
    • Walsh CM, Glass AA, Chiu V et al. The role of the Fas lytic pathway in a perforin-less CTL hybridoma. J Immunol 1994;153:2506-2514.
    • (1994) J Immunol , vol.153 , pp. 2506-2514
    • Walsh, C.M.1    Glass, A.A.2    Chiu, V.3
  • 19
    • 0028962125 scopus 로고
    • Fas-mediated cytotoxicity by freshly isolated natural killer cells
    • Arase H, Arase N, Saito T. Fas-mediated cytotoxicity by freshly isolated natural killer cells. J Exp Med 1995;181:1235-1238.
    • (1995) J Exp Med , vol.181 , pp. 1235-1238
    • Arase, H.1    Arase, N.2    Saito, T.3
  • 20
    • 0030738018 scopus 로고    scopus 로고
    • Role for NK-cell-associated Fas ligand in cell-mediated cytotoxicity and apoptosis
    • Eischen CM, Leibson PJ. Role for NK-cell-associated Fas ligand in cell-mediated cytotoxicity and apoptosis. Res Immunol 1997;148:164-169.
    • (1997) Res Immunol , vol.148 , pp. 164-169
    • Eischen, C.M.1    Leibson, P.J.2
  • 21
    • 0028360966 scopus 로고
    • Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity
    • Hanabuchi S, Koyanagi M, Kawasaki A et al. Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity. Proc Natl Acad Sci U S A 1994;91:4930-4934.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 4930-4934
    • Hanabuchi, S.1    Koyanagi, M.2    Kawasaki, A.3
  • 25
    • 0032841840 scopus 로고    scopus 로고
    • Autoantigen-specific B cell activation in Fas-deficient rheumatoid factor immunoglobulin transgenic mice
    • Wang H, Shlomchik MJ. Autoantigen-specific B cell activation in Fas-deficient rheumatoid factor immunoglobulin transgenic mice. J Exp Med 1999;190:639-649.
    • (1999) J Exp Med , vol.190 , pp. 639-649
    • Wang, H.1    Shlomchik, M.J.2
  • 26
    • 0034667781 scopus 로고    scopus 로고
    • Unexpected autoantibody production in membrane Ig-mu-deficient/lpr mice
    • Melamed D, Miri E, Leider N et al. Unexpected autoantibody production in membrane Ig-mu-deficient/lpr mice. J Immunol 2000;165:4353-4358.
    • (2000) J Immunol , vol.165 , pp. 4353-4358
    • Melamed, D.1    Miri, E.2    Leider, N.3
  • 27
    • 0027145632 scopus 로고
    • Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
    • Suda T, Takahashi T, Golstein P et al. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 1993;75:1169-1178.
    • (1993) Cell , vol.75 , pp. 1169-1178
    • Suda, T.1    Takahashi, T.2    Golstein, P.3
  • 28
    • 0029026548 scopus 로고
    • FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
    • Chinnaiyan AM, O'Rourke K, Tewari M et al. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 1995;81:505-512.
    • (1995) Cell , vol.81 , pp. 505-512
    • Chinnaiyan, A.M.1    O'Rourke, K.2    Tewari, M.3
  • 29
    • 0028913550 scopus 로고
    • A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain
    • Boldin MP, Varfolomeev EE, Pancer Z et al. A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain. J Biol Chem 1995;270:7795-7798.
    • (1995) J Biol Chem , vol.270 , pp. 7795-7798
    • Boldin, M.P.1    Varfolomeev, E.E.2    Pancer, Z.3
  • 30
    • 0028883850 scopus 로고
    • Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
    • Kischkel FC, Hellbardt S, Behrmann I et al. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J 1995;14:5579-5588.
    • (1995) EMBO J , vol.14 , pp. 5579-5588
    • Kischkel, F.C.1    Hellbardt, S.2    Behrmann, I.3
  • 31
    • 15844412409 scopus 로고    scopus 로고
    • FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
    • Muzio M, Chinnaiyan AM, Kischkel FC et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 1996;85:817-827.
    • (1996) Cell , vol.85 , pp. 817-827
    • Muzio, M.1    Chinnaiyan, A.M.2    Kischkel, F.C.3
  • 32
    • 0030011398 scopus 로고    scopus 로고
    • Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
    • Boldin MP, Goncharov TM, Goltsev YV et al. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell 1996;85:803-815.
    • (1996) Cell , vol.85 , pp. 803-815
    • Boldin, M.P.1    Goncharov, T.M.2    Goltsev, Y.V.3
  • 33
    • 0030934465 scopus 로고    scopus 로고
    • Fas-associated death domain protein interleukin-1 beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling
    • Vincenz C, Dixit VM. Fas-associated death domain protein interleukin-1 beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling. J Biol Chem 1997;272:6578-6583.
    • (1997) J Biol Chem , vol.272 , pp. 6578-6583
    • Vincenz, C.1    Dixit, V.M.2
  • 34
    • 0035923653 scopus 로고    scopus 로고
    • Caspase-10 is an initiator caspase in death receptor signaling
    • Wang J, Chun HJ, Wong W et al. Caspase-10 is an initiator caspase in death receptor signaling. Proc Natl Acad Sci U S A 2001;98:13884-13888.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 13884-13888
    • Wang, J.1    Chun, H.J.2    Wong, W.3
  • 35
    • 0035824635 scopus 로고    scopus 로고
    • Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8
    • Kischkel FC, Lawrence DA, Tinel A et al. Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8. J Biol Chem 2001;276:46639-46646.
    • (2001) J Biol Chem , vol.276 , pp. 46639-46646
    • Kischkel, F.C.1    Lawrence, D.A.2    Tinel, A.3
  • 36
    • 0032536771 scopus 로고    scopus 로고
    • Two CD95 (APO-1/Fas) signaling pathways
    • Scaffidi C, Fulda S, Srinivasan A et al. Two CD95 (APO-1/Fas) signaling pathways. EMBO J 1998;17:1675-1687.
    • (1998) EMBO J , vol.17 , pp. 1675-1687
    • Scaffidi, C.1    Fulda, S.2    Srinivasan, A.3
  • 38
    • 0032555697 scopus 로고    scopus 로고
    • Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
    • Li H, Zhu H, Xu CJ et al. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998;94:491-501.
    • (1998) Cell , vol.94 , pp. 491-501
    • Li, H.1    Zhu, H.2    Xu, C.J.3
  • 39
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo X, Budihardjo I, Zou H et al. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998;94:481-490.
    • (1998) Cell , vol.94 , pp. 481-490
    • Luo, X.1    Budihardjo, I.2    Zou, H.3
  • 40
    • 0033981577 scopus 로고    scopus 로고
    • Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane
    • Eskes R, Desagher S, Antonsson B et al. Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane. Mol Cell Biol 2000;20:929-935.
    • (2000) Mol Cell Biol , vol.20 , pp. 929-935
    • Eskes, R.1    Desagher, S.2    Antonsson, B.3
  • 41
    • 0034663829 scopus 로고    scopus 로고
    • tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c
    • Wei MC, Lindsten T, Mootha VK et al. tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c. Genes Dev 2000;14:2060-2071.
    • (2000) Genes Dev , vol.14 , pp. 2060-2071
    • Wei, M.C.1    Lindsten, T.2    Mootha, V.K.3
  • 42
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P, Nijhawan D, Budihardjo I et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479-489.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3
  • 43
    • 0033596980 scopus 로고    scopus 로고
    • An APAF-1 cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
    • Zou H, Li Y, Liu X et al. An APAF-1 cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J Biol Chem 1999;274:11549-11556.
    • (1999) J Biol Chem , vol.274 , pp. 11549-11556
    • Zou, H.1    Li, Y.2    Liu, X.3
  • 44
    • 0033607006 scopus 로고    scopus 로고
    • Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis
    • Yin XM, Wang K, Gross A et al. Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature 1999;400:886-891.
    • (1999) Nature , vol.400 , pp. 886-891
    • Yin, X.M.1    Wang, K.2    Gross, A.3
  • 45
    • 0035957653 scopus 로고    scopus 로고
    • Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
    • Wei MC, Zong WX, Cheng EH et al. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 2001;292:727-730.
    • (2001) Science , vol.292 , pp. 727-730
    • Wei, M.C.1    Zong, W.X.2    Cheng, E.H.3
  • 46
    • 0141853168 scopus 로고    scopus 로고
    • Live and let die: Regulatory mechanisms in Fas-mediated apoptosis
    • Curtin JF, Cotter TG. Live and let die: regulatory mechanisms in Fas-mediated apoptosis. Cell Signal 2003;15:983-992.
    • (2003) Cell Signal , vol.15 , pp. 983-992
    • Curtin, J.F.1    Cotter, T.G.2
  • 47
    • 0028804857 scopus 로고
    • Metalloproteinase-mediated release of human Fas ligand
    • Kayagaki N, Kawasaki A, Ebata T et al. Metalloproteinase-mediated release of human Fas ligand. J Exp Med 1995;182:1777-1783.
    • (1995) J Exp Med , vol.182 , pp. 1777-1783
    • Kayagaki, N.1    Kawasaki, A.2    Ebata, T.3
  • 48
    • 0028919473 scopus 로고
    • Expression of the functional soluble form of human fas ligand in activated lymphocytes
    • Tanaka M, Suda T, Takahashi T et al. Expression of the functional soluble form of human fas ligand in activated lymphocytes. EMBO J 1995;14:1129-1135.
    • (1995) EMBO J , vol.14 , pp. 1129-1135
    • Tanaka, M.1    Suda, T.2    Takahashi, T.3
  • 49
    • 0033576645 scopus 로고    scopus 로고
    • The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis
    • Powell WC, Fingleton B, Wilson CL et al. The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis. Curr Biol 1999;9:1441-1447.
    • (1999) Curr Biol , vol.9 , pp. 1441-1447
    • Powell, W.C.1    Fingleton, B.2    Wilson, C.L.3
  • 50
    • 0035318305 scopus 로고    scopus 로고
    • Extracellular matrix interacts with soluble CD95L: Retention and enhancement of cytotoxicity
    • Aoki K, Kurooka M, Chen JJ et al. Extracellular matrix interacts with soluble CD95L: retention and enhancement of cytotoxicity. Nat Immunol 2001;2:333-337.
    • (2001) Nat Immunol , vol.2 , pp. 333-337
    • Aoki, K.1    Kurooka, M.2    Chen, J.J.3
  • 51
    • 0032860304 scopus 로고    scopus 로고
    • Increased serum soluble Fas ligand associated with recurrent B-cell non-Hodgkin's lymphoma after autologous peripheral blood stem cell transplantation
    • Kanda Y, Chiba S, Tanaka Y et al. Increased serum soluble Fas ligand associated with recurrent B-cell non-Hodgkin's lymphoma after autologous peripheral blood stem cell transplantation. Leuk Lymphoma 1999;34:625-628.
    • (1999) Leuk Lymphoma , vol.34 , pp. 625-628
    • Kanda, Y.1    Chiba, S.2    Tanaka, Y.3
  • 52
    • 0035878616 scopus 로고    scopus 로고
    • Significance of serum soluble Fas ligand in patients with bladder carcinoma
    • Mizutani Y, Hongo F, Sato N et al. Significance of serum soluble Fas ligand in patients with bladder carcinoma. Cancer 2001;92:287-293.
    • (2001) Cancer , vol.92 , pp. 287-293
    • Mizutani, Y.1    Hongo, F.2    Sato, N.3
  • 54
    • 0033826458 scopus 로고    scopus 로고
    • Soluble Fas-ligand (sFasL) in human astrocytoma cyst fluid is cytotoxic to T-cells: Another potential means of immune evasion
    • Frankel B, Longo SL, Canute GW. Soluble Fas-ligand (sFasL) in human astrocytoma cyst fluid is cytotoxic to T-cells: another potential means of immune evasion. J Neurooncol 2000;48:21-26.
    • (2000) J Neurooncol , vol.48 , pp. 21-26
    • Frankel, B.1    Longo, S.L.2    Canute, G.W.3
  • 55
    • 0035964621 scopus 로고    scopus 로고
    • Soluble Fas ligand released by colon adenocarcinoma cells induces host lymphocyte apoptosis: An active mode of immune evasion in colon cancer
    • Song E, Chen J, Ouyang N et al. Soluble Fas ligand released by colon adenocarcinoma cells induces host lymphocyte apoptosis: an active mode of immune evasion in colon cancer. Br J Cancer 2001;85:1047-1054.
    • (2001) Br J Cancer , vol.85 , pp. 1047-1054
    • Song, E.1    Chen, J.2    Ouyang, N.3
  • 56
    • 14844345988 scopus 로고
    • Expression of the Fas ligand in cells of T cell lineage
    • Suda T, Okazaki T, Naito Y et al. Expression of the Fas ligand in cells of T cell lineage. J Immunol 1995;154:3806-3813.
    • (1995) J Immunol , vol.154 , pp. 3806-3813
    • Suda, T.1    Okazaki, T.2    Naito, Y.3
  • 57
    • 0028879109 scopus 로고
    • Fas ligand-induced apoptosis as a mechanism of immune privilege
    • Griffith TS, Brunner T, Fletcher SM et al. Fas ligand-induced apoptosis as a mechanism of immune privilege. Science 1995;270:1189-1192.
    • (1995) Science , vol.270 , pp. 1189-1192
    • Griffith, T.S.1    Brunner, T.2    Fletcher, S.M.3
  • 58
    • 0033583427 scopus 로고    scopus 로고
    • Dual role for Fas ligand in the initiation of and recovery from experimental allergic encephalomyelitis
    • Sabelko-Downes KA, Cross AH, Russell JH. Dual role for Fas ligand in the initiation of and recovery from experimental allergic encephalomyelitis. J Exp Med 1999;189:1195-1205.
    • (1999) J Exp Med , vol.189 , pp. 1195-1205
    • Sabelko-Downes, K.A.1    Cross, A.H.2    Russell, J.H.3
  • 59
    • 0033954469 scopus 로고    scopus 로고
    • Fas-mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis
    • Suvannavejh GC, Dal Canto MC, Matis LA et al. Fas-mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis. J Clin Invest 2000;105:223-231.
    • (2000) J Clin Invest , vol.105 , pp. 223-231
    • Suvannavejh, G.C.1    Dal Canto, M.C.2    Matis, L.A.3
  • 60
    • 0031943598 scopus 로고    scopus 로고
    • Airway epithelial Fas ligand expression: Potential role in modulating bronchial inflammation
    • Gochuico BR, Miranda KM, Hessel EM et al. Airway epithelial Fas ligand expression: potential role in modulating bronchial inflammation. Am J Physiol 1998;274:L444-449.
    • (1998) Am J Physiol , vol.274
    • Gochuico, B.R.1    Miranda, K.M.2    Hessel, E.M.3
  • 61
    • 0031132872 scopus 로고    scopus 로고
    • Fas ligand is positioned in mouse uterus and placenta to prevent trafficking of activated leukocytes between the mother and the conceptus
    • Hunt JS, Vassmer D, Ferguson TA et al. Fas ligand is positioned in mouse uterus and placenta to prevent trafficking of activated leukocytes between the mother and the conceptus. J Immunol 1997;158:4122-4128.
    • (1997) J Immunol , vol.158 , pp. 4122-4128
    • Hunt, J.S.1    Vassmer, D.2    Ferguson, T.A.3
  • 63
    • 0032913834 scopus 로고    scopus 로고
    • Fas-FasL interaction involved in pathogenesis of ocular toxoplasmosis in mice
    • Hu MS, Schwartzman JD, Yeaman GR et al. Fas-FasL interaction involved in pathogenesis of ocular toxoplasmosis in mice. Infect Immunol 1999;67:928-935.
    • (1999) Infect Immunol , vol.67 , pp. 928-935
    • Hu, M.S.1    Schwartzman, J.D.2    Yeaman, G.R.3
  • 64
    • 0030821649 scopus 로고    scopus 로고
    • CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival
    • Stuart PM, Griffith TS, Usui N et al. CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival. J Clin Invest 1997;99:396-402.
    • (1997) J Clin Invest , vol.99 , pp. 396-402
    • Stuart, P.M.1    Griffith, T.S.2    Usui, N.3
  • 65
    • 0029808372 scopus 로고    scopus 로고
    • The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand
    • O'Connell J, O'Sullivan GC, Collins JK et al. The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand. J Exp Med 1996;184:1075-1082.
    • (1996) J Exp Med , vol.184 , pp. 1075-1082
    • O'Connell, J.1    O'Sullivan, G.C.2    Collins, J.K.3
  • 66
    • 0242266480 scopus 로고    scopus 로고
    • Fas ligand mediates immune privilege and not inflammation in human colon cancer, irrespective of TGF-beta expression
    • Houston A, Bennett MW, O'Sullivan GC et al. Fas ligand mediates immune privilege and not inflammation in human colon cancer, irrespective of TGF-beta expression. Br J Cancer 2003;89:1345-1351.
    • (2003) Br J Cancer , vol.89 , pp. 1345-1351
    • Houston, A.1    Bennett, M.W.2    O'Sullivan, G.C.3
  • 67
    • 0141523113 scopus 로고    scopus 로고
    • Fas ligand expressed in colon cancer is not associated with increased apoptosis of tumor cells in vivo
    • Houston A, Waldron-Lynch FD, Bennett MW et al. Fas ligand expressed in colon cancer is not associated with increased apoptosis of tumor cells in vivo. Int J Cancer 2003;107:209-214.
    • (2003) Int J Cancer , vol.107 , pp. 209-214
    • Houston, A.1    Waldron-Lynch, F.D.2    Bennett, M.W.3
  • 68
    • 0038648279 scopus 로고    scopus 로고
    • Fas ligand expression is correlated with metastasis in colorectal carcinoma
    • Nozoe T, Yasuda M, Honda M et al. Fas ligand expression is correlated with metastasis in colorectal carcinoma. Oncology 2003;65:83-88.
    • (2003) Oncology , vol.65 , pp. 83-88
    • Nozoe, T.1    Yasuda, M.2    Honda, M.3
  • 69
    • 10544232277 scopus 로고    scopus 로고
    • Melanoma cell expression of Fas(Apo-1/CD95) ligand: Implications for tumor immune escape
    • Hahne M, Rimoldi D, Schroter M et al. Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape. Science 1996;274:1363-1366.
    • (1996) Science , vol.274 , pp. 1363-1366
    • Hahne, M.1    Rimoldi, D.2    Schroter, M.3
  • 70
    • 0042847257 scopus 로고    scopus 로고
    • Fas ligand on tumor cells mediates inactivation of neutrophils
    • Chen YL, Chen SH, Wang JY et al. Fas ligand on tumor cells mediates inactivation of neutrophils. J Immunol 2003;171:1183-1191.
    • (2003) J Immunol , vol.171 , pp. 1183-1191
    • Chen, Y.L.1    Chen, S.H.2    Wang, J.Y.3
  • 71
    • 0032698214 scopus 로고    scopus 로고
    • Fas ligand is expressed on human squamous cell carcinomas of the head and neck, and it promotes apoptosis of T lymphocytes
    • Gastman BR, Atarshi Y, Reichert TE et al. Fas ligand is expressed on human squamous cell carcinomas of the head and neck, and it promotes apoptosis of T lymphocytes. Cancer Res 1999;59:5356-5364.
    • (1999) Cancer Res , vol.59 , pp. 5356-5364
    • Gastman, B.R.1    Atarshi, Y.2    Reichert, T.E.3
  • 72
    • 0036023415 scopus 로고    scopus 로고
    • Spontaneous apoptosis of circulating T lymphocytes in patients with head and neck cancer and its clinical importance
    • Hoffmann TK, Dworacki G, Tsukihiro T et al. Spontaneous apoptosis of circulating T lymphocytes in patients with head and neck cancer and its clinical importance. Clin Cancer Res 2002;8:2553-2562.
    • (2002) Clin Cancer Res , vol.8 , pp. 2553-2562
    • Hoffmann, T.K.1    Dworacki, G.2    Tsukihiro, T.3
  • 73
    • 16144363507 scopus 로고    scopus 로고
    • Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells: A mechanism of immune evasion?
    • Strand S, Hofmann WJ, Hug H et al. Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells: a mechanism of immune evasion? Nat Med 1996;2:1361-1366.
    • (1996) Nat Med , vol.2 , pp. 1361-1366
    • Strand, S.1    Hofmann, W.J.2    Hug, H.3
  • 74
    • 0030933337 scopus 로고    scopus 로고
    • Human lung carcinomas express Fas ligand
    • Niehans GA, Brunner T, Frizelle SP et al. Human lung carcinomas express Fas ligand. Cancer Res 1997;57:1007-1012.
    • (1997) Cancer Res , vol.57 , pp. 1007-1012
    • Niehans, G.A.1    Brunner, T.2    Frizelle, S.P.3
  • 75
    • 0141926700 scopus 로고    scopus 로고
    • Frequent loss of Fas expression and function in human lung tumours with overexpression of FasL in small cell lung carcinoma
    • Viard-Leveugle I, Veyrenc S, French LE et al. Frequent loss of Fas expression and function in human lung tumours with overexpression of FasL in small cell lung carcinoma. J Pathol 2003;201:268-277.
    • (2003) J Pathol , vol.201 , pp. 268-277
    • Viard-Leveugle, I.1    Veyrenc, S.2    French, L.E.3
  • 76
    • 0030959255 scopus 로고    scopus 로고
    • Constitutive expression of Fas (Apo-1/CD95) ligand on multiple myeloma cells: A potential mechanism of tumor-induced suppression of immune surveillance
    • Villunger A, Egle A, Marschitz I et al. Constitutive expression of Fas (Apo-1/CD95) ligand on multiple myeloma cells: a potential mechanism of tumor-induced suppression of immune surveillance. Blood 1997;90:12-20.
    • (1997) Blood , vol.90 , pp. 12-20
    • Villunger, A.1    Egle, A.2    Marschitz, I.3
  • 77
    • 0036786033 scopus 로고    scopus 로고
    • Expression of functional Fas ligand in choriocarcinoma
    • Hammer A, Hartmann M, Sedlmayr P et al. Expression of functional Fas ligand in choriocarcinoma. Am J Reprod Immunol 2002;48:226-234.
    • (2002) Am J Reprod Immunol , vol.48 , pp. 226-234
    • Hammer, A.1    Hartmann, M.2    Sedlmayr, P.3
  • 78
    • 0032103027 scopus 로고    scopus 로고
    • The Fas counterattack in vivo: Apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas ligand expression by human esophageal carcinoma
    • Bennett MW, O'Connell J, O'Sullivan GC et al. The Fas counterattack in vivo: apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas ligand expression by human esophageal carcinoma. J Immunol 1998;160:5669-5675.
    • (1998) J Immunol , vol.160 , pp. 5669-5675
    • Bennett, M.W.1    O'Connell, J.2    O'Sullivan, G.C.3
  • 79
    • 0031472398 scopus 로고    scopus 로고
    • Gene transfer of Fas ligand induces tumor regression in vivo
    • Arai H, Gordon D, Nabel EG et al. Gene transfer of Fas ligand induces tumor regression in vivo. Proc Natl Acad Sci U S A 1997;94:13862-13867.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 13862-13867
    • Arai, H.1    Gordon, D.2    Nabel, E.G.3
  • 80
    • 0030951155 scopus 로고    scopus 로고
    • Rejection of Fas ligand-expressing grafts
    • Seino K, Kayagaki N, Fukao K et al. Rejection of Fas ligand-expressing grafts. Transplant Proc 1997;29:1092-1093.
    • (1997) Transplant Proc , vol.29 , pp. 1092-1093
    • Seino, K.1    Kayagaki, N.2    Fukao, K.3
  • 81
    • 0036348187 scopus 로고    scopus 로고
    • Pathways of allorecognition: Implications for transplantation tolerance
    • Game DS, Lechler RI. Pathways of allorecognition: implications for transplantation tolerance. Transpl Immunol 2002;10:101-108.
    • (2002) Transpl Immunol , vol.10 , pp. 101-108
    • Game, D.S.1    Lechler, R.I.2
  • 82
    • 0035025617 scopus 로고    scopus 로고
    • Chronic rejection
    • Libby P, Pober JS. Chronic rejection. Immunity 2001;14:387-397.
    • (2001) Immunity , vol.14 , pp. 387-397
    • Libby, P.1    Pober, J.S.2
  • 83
    • 0031027777 scopus 로고    scopus 로고
    • Infections in solid-organ transplant recipients
    • Patel R, Paya CV. Infections in solid-organ transplant recipients. Clin Microbiol Rev 1997;10:86-124.
    • (1997) Clin Microbiol Rev , vol.10 , pp. 86-124
    • Patel, R.1    Paya, C.V.2
  • 84
    • 0032508056 scopus 로고    scopus 로고
    • Infection in organ-transplant recipients
    • Fishman JA, Rubin RH. Infection in organ-transplant recipients. N Engl J Med 1998;338:1741-1751.
    • (1998) N Engl J Med , vol.338 , pp. 1741-1751
    • Fishman, J.A.1    Rubin, R.H.2
  • 85
    • 0037393121 scopus 로고    scopus 로고
    • Immunosuppressive drugs and cancer
    • Vial T, Descotes J. Immunosuppressive drugs and cancer. Toxicology 2003;185:229-240.
    • (2003) Toxicology , vol.185 , pp. 229-240
    • Vial, T.1    Descotes, J.2
  • 86
    • 0030201014 scopus 로고    scopus 로고
    • CD95-induced apoptosis of lymphocytes in an immune privileged site induces immunological tolerance
    • Griffith TS, Yu X, Herndon JM et al. CD95-induced apoptosis of lymphocytes in an immune privileged site induces immunological tolerance. Immunity 1996;5:7-16.
    • (1996) Immunity , vol.5 , pp. 7-16
    • Griffith, T.S.1    Yu, X.2    Herndon, J.M.3
  • 87
    • 0030657597 scopus 로고    scopus 로고
    • Anterior chamber inoculation of splenocytes without Fas/Fas-ligand interaction primes for a delayed-type hypersensitivity response rather than inducing anterior chamber-associated immune deviation
    • Kawashima H, Yamagami S, Tsuru T et al. Anterior chamber inoculation of splenocytes without Fas/Fas-ligand interaction primes for a delayed-type hypersensitivity response rather than inducing anterior chamber-associated immune deviation. Eur J Immunol 1997;27:2490-2494.
    • (1997) Eur J Immunol , vol.27 , pp. 2490-2494
    • Kawashima, H.1    Yamagami, S.2    Tsuru, T.3
  • 88
    • 0033583526 scopus 로고    scopus 로고
    • A critical role for Fas ligand in the active suppression of systemic immune responses by ultraviolet radiation
    • Hill LL, Shreedhar VK, Kripke ML et al. A critical role for Fas ligand in the active suppression of systemic immune responses by ultraviolet radiation. J Exp Med 1999;189:1285-1294.
    • (1999) J Exp Med , vol.189 , pp. 1285-1294
    • Hill, L.L.1    Shreedhar, V.K.2    Kripke, M.L.3
  • 89
    • 0034642522 scopus 로고    scopus 로고
    • Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages
    • Freire-de-Lima CG, Nascimento DO, Soares MB et al. Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages. Nature 2000;403:199-203.
    • (2000) Nature , vol.403 , pp. 199-203
    • Freire-De-Lima, C.G.1    Nascimento, D.O.2    Soares, M.B.3
  • 90
    • 0034614886 scopus 로고    scopus 로고
    • The induction of tolerance by dendritic cells that have captured apoptotic cells
    • Steinman RM, Turley S, Mellman I et al. The induction of tolerance by dendritic cells that have captured apoptotic cells. J Exp Med 2000;191:411-416.
    • (2000) J Exp Med , vol.191 , pp. 411-416
    • Steinman, R.M.1    Turley, S.2    Mellman, I.3
  • 91
    • 0035284802 scopus 로고    scopus 로고
    • Fas/Fas ligand pathway, apoptosis, and clonal anergy involved in systemic acetylcholine receptor T cell epitope tolerance
    • Deng C, Goluszko E, Christadoss P. Fas/Fas ligand pathway, apoptosis, and clonal anergy involved in systemic acetylcholine receptor T cell epitope tolerance. J Immunol 2001;166:3458-3467.
    • (2001) J Immunol , vol.166 , pp. 3458-3467
    • Deng, C.1    Goluszko, E.2    Christadoss, P.3
  • 92
    • 0038510113 scopus 로고    scopus 로고
    • Apoptosis, tolerance, and regulatory T cells: Old wine, new wineskins
    • Ferguson TA, Stuart PM, Herndon JM et al. Apoptosis, tolerance, and regulatory T cells: old wine, new wineskins. Immunol Rev 2003;193:111-123.
    • (2003) Immunol Rev , vol.193 , pp. 111-123
    • Ferguson, T.A.1    Stuart, P.M.2    Herndon, J.M.3
  • 93
    • 0037833620 scopus 로고    scopus 로고
    • Apoptosis and transplantation tolerance
    • Chiffoleau E, Walsh PT, Turka L. Apoptosis and transplantation tolerance. Immunol Rev 2003;193:124-145.
    • (2003) Immunol Rev , vol.193 , pp. 124-145
    • Chiffoleau, E.1    Walsh, P.T.2    Turka, L.3
  • 94
    • 0032494144 scopus 로고    scopus 로고
    • Antiinflammatory effects of CD95 ligand (FasL)-induced apoptosis
    • Gao Y, Herndon JM, Zhang H et al. Antiinflammatory effects of CD95 ligand (FasL)-induced apoptosis. J Exp Med 1998;188:887-896.
    • (1998) J Exp Med , vol.188 , pp. 887-896
    • Gao, Y.1    Herndon, J.M.2    Zhang, H.3
  • 95
    • 0345628010 scopus 로고    scopus 로고
    • Fas ligand gene transfer to renal allografts in rats: Effects on allograft survival
    • Swenson KM, Ke B, Wang T et al. Fas ligand gene transfer to renal allografts in rats: effects on allograft survival. Transplantation 1998;65:155-160.
    • (1998) Transplantation , vol.65 , pp. 155-160
    • Swenson, K.M.1    Ke, B.2    Wang, T.3
  • 96
    • 0034720048 scopus 로고    scopus 로고
    • Fas ligand gene transfer prolongs rat renal allograft survival and down-regulates anti-apoptotic Bag-1 in parallel with enhanced Th2-type cytokine expression
    • Ke B, Coito AJ, Kato H et al. Fas ligand gene transfer prolongs rat renal allograft survival and down-regulates anti-apoptotic Bag-1 in parallel with enhanced Th2-type cytokine expression. Transplantation 2000;69:1690-1694.
    • (2000) Transplantation , vol.69 , pp. 1690-1694
    • Ke, B.1    Coito, A.J.2    Kato, H.3
  • 97
    • 0032961753 scopus 로고    scopus 로고
    • Accelerated rejection of Fas ligand-expressing heart grafts
    • Takeuchi T, Ueki T, Nishimatsu H et al. Accelerated rejection of Fas ligand-expressing heart grafts. J Immunol 1999;162:518-522.
    • (1999) J Immunol , vol.162 , pp. 518-522
    • Takeuchi, T.1    Ueki, T.2    Nishimatsu, H.3
  • 98
    • 0037465727 scopus 로고    scopus 로고
    • Display of Fas ligand protein on cardiac vasculature as a novel means of regulating allograft rejection
    • Askenasy N, Yolcu ES, Wang Z et al. Display of Fas ligand protein on cardiac vasculature as a novel means of regulating allograft rejection. Circulation 2003;107:1525-1531.
    • (2003) Circulation , vol.107 , pp. 1525-1531
    • Askenasy, N.1    Yolcu, E.S.2    Wang, Z.3
  • 99
    • 0033970592 scopus 로고    scopus 로고
    • Dendritic cells genetically engineered to express Fas ligand induce donor-specific hyporesponsiveness and prolong allograft survival
    • Min WP, Gorczynski R, Huang XY et al. Dendritic cells genetically engineered to express Fas ligand induce donor-specific hyporesponsiveness and prolong allograft survival. J Immunol 2000;164:161-167.
    • (2000) J Immunol , vol.164 , pp. 161-167
    • Min, W.P.1    Gorczynski, R.2    Huang, X.Y.3
  • 100
    • 0031594280 scopus 로고    scopus 로고
    • TNFα regulation of Fas ligand expression on the vascular endothelium modulates leukocyte extravasation
    • Sata M, Walsh K. TNFα regulation of Fas ligand expression on the vascular endothelium modulates leukocyte extravasation. Nat Med 1998;4:415-420.
    • (1998) Nat Med , vol.4 , pp. 415-420
    • Sata, M.1    Walsh, K.2
  • 101
    • 0343773374 scopus 로고    scopus 로고
    • Fas ligand overexpression on allograft endothelium inhibits inflammatory cell infiltration and transplant-associated intimal hyperplasia
    • Sata M, Luo Z, Walsh K. Fas ligand overexpression on allograft endothelium inhibits inflammatory cell infiltration and transplant-associated intimal hyperplasia. J Immunol 2001;166:6964-6971.
    • (2001) J Immunol , vol.166 , pp. 6964-6971
    • Sata, M.1    Luo, Z.2    Walsh, K.3
  • 102
    • 0032477728 scopus 로고    scopus 로고
    • Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T cell response
    • Sata M, Perlman H, Muruve DA et al. Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T cell response. Proc Natl Acad Sci USA 1998;95:1213-1217.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 1213-1217
    • Sata, M.1    Perlman, H.2    Muruve, D.A.3
  • 103
    • 0033551097 scopus 로고    scopus 로고
    • Adenovirus-mediated delivery of fas ligand inhibits intimal hyperplasia after balloon injury in immunologically primed animals
    • Luo Z, Sata M, Nguyen T et al. Adenovirus-mediated delivery of fas ligand inhibits intimal hyperplasia after balloon injury in immunologically primed animals. Circulation 1999;99:1776-1779.
    • (1999) Circulation , vol.99 , pp. 1776-1779
    • Luo, Z.1    Sata, M.2    Nguyen, T.3
  • 104
    • 0037674862 scopus 로고    scopus 로고
    • Endothelial cell overexpression of Fas ligand attenuates ischemia-reperfusion injury in the heart
    • Yang J, Jones SP, Suhara T et al. Endothelial cell overexpression of Fas ligand attenuates ischemia-reperfusion injury in the heart. J Biol Chem 2003;278:15185-15191.
    • (2003) J Biol Chem , vol.278 , pp. 15185-15191
    • Yang, J.1    Jones, S.P.2    Suhara, T.3
  • 105
    • 0032534867 scopus 로고    scopus 로고
    • Prolonged survival of rat liver allografts transfected with Fas ligand-expressing plasmid
    • Li XK, Okuyama T, Tamura A et al. Prolonged survival of rat liver allografts transfected with Fas ligand-expressing plasmid. Transplantation 1998;66:1416-1423.
    • (1998) Transplantation , vol.66 , pp. 1416-1423
    • Li, X.K.1    Okuyama, T.2    Tamura, A.3
  • 106
    • 0000724272 scopus 로고    scopus 로고
    • Fas ligand gene transfer combined with low dose cyclosporine A reduces acute lung allograft rejection
    • Schmid RA, Stammberger U, Hillinger S et al. Fas ligand gene transfer combined with low dose cyclosporine A reduces acute lung allograft rejection. Transpl Int 2000;13(suppl 1):S324-S328.
    • (2000) Transpl Int , vol.13 , Issue.SUPPL. 1
    • Schmid, R.A.1    Stammberger, U.2    Hillinger, S.3
  • 107
    • 0033888027 scopus 로고    scopus 로고
    • Selective upregulation of fibroblast Fas ligand expression, and prolongation of Fas/Fas ligand-mediated skin allograft survival, by retinoic acid: The skin as a retinoide-inducible immune privilege site
    • Saitoh A, Kawanabe T, Weidong H et al. Selective upregulation of fibroblast Fas ligand expression, and prolongation of Fas/Fas ligand-mediated skin allograft survival, by retinoic acid: the skin as a retinoide-inducible immune privilege site. J Invest Dermatol 2000;115:154-161.
    • (2000) J Invest Dermatol , vol.115 , pp. 154-161
    • Saitoh, A.1    Kawanabe, T.2    Weidong, H.3
  • 108
    • 0035421771 scopus 로고    scopus 로고
    • Transgenic expression of CD95 ligand on thyroid follicular cells confers immune privilege upon thyroid allografts
    • Tourneur L, Malassagne B, Batteux F et al. Transgenic expression of CD95 ligand on thyroid follicular cells confers immune privilege upon thyroid allografts. J Immunol 2001;167:1338-1346.
    • (2001) J Immunol , vol.167 , pp. 1338-1346
    • Tourneur, L.1    Malassagne, B.2    Batteux, F.3
  • 109
    • 0030972396 scopus 로고    scopus 로고
    • Transgenic expression of CD95 ligand on islet beta cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts
    • Allison J, Georgiou HM, Strasser A et al. Transgenic expression of CD95 ligand on islet beta cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts. Proc Natl Acad Sci U S A 1997;94:3943-3947.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 3943-3947
    • Allison, J.1    Georgiou, H.M.2    Strasser, A.3
  • 110
    • 0030842535 scopus 로고    scopus 로고
    • Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction
    • Kang SM, Schneider DB, Lin Z et al. Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction. Nat Med 1997;3:738-743.
    • (1997) Nat Med , vol.3 , pp. 738-743
    • Kang, S.M.1    Schneider, D.B.2    Lin, Z.3
  • 112
    • 0030903088 scopus 로고    scopus 로고
    • Cotransplantation of allogeneic islets with allogeneic testicular cell aggregates allows long-term graft survival without systemic immunosuppression
    • Korbutt GS, Elliott JF, Rajotte RV. Cotransplantation of allogeneic islets with allogeneic testicular cell aggregates allows long-term graft survival without systemic immunosuppression. Diabetes 1997;46:317-322.
    • (1997) Diabetes , vol.46 , pp. 317-322
    • Korbutt, G.S.1    Elliott, J.F.2    Rajotte, R.V.3
  • 113
    • 15644363704 scopus 로고    scopus 로고
    • Protection of islet allografts transplanted together with Fas ligand expressing testicular allografts
    • Takeda Y, Gotoh M, Dono K et al. Protection of islet allografts transplanted together with Fas ligand expressing testicular allografts. Diabetologia 1998;41:315-321.
    • (1998) Diabetologia , vol.41 , pp. 315-321
    • Takeda, Y.1    Gotoh, M.2    Dono, K.3
  • 114
    • 0030017476 scopus 로고    scopus 로고
    • Prevention of islet allograft rejection with engineered myoblasts expressing FasL in mice
    • Lau HT, Yu M, Fontana A et al. Prevention of islet allograft rejection with engineered myoblasts expressing FasL in mice. Science 1996;273:109-112.
    • (1996) Science , vol.273 , pp. 109-112
    • Lau, H.T.1    Yu, M.2    Fontana, A.3
  • 115
    • 0034658457 scopus 로고    scopus 로고
    • Fas ligand-transfected myoblasts and islet cell transplantation
    • Turvey SE, Gonzalez-Nicolini V, Kingsley CI et al. Fas ligand-transfected myoblasts and islet cell transplantation. Transplantation 2000;69:1972-1976.
    • (2000) Transplantation , vol.69 , pp. 1972-1976
    • Turvey, S.E.1    Gonzalez-Nicolini, V.2    Kingsley, C.I.3
  • 116
    • 0030680119 scopus 로고    scopus 로고
    • Immune response and myoblasts that express Fas ligand
    • Kang SM, Hoffmann A, Le D et al. Immune response and myoblasts that express Fas ligand. Science 1997;278:1322-1324.
    • (1997) Science , vol.278 , pp. 1322-1324
    • Kang, S.M.1    Hoffmann, A.2    Le, D.3
  • 117
    • 18744416830 scopus 로고    scopus 로고
    • Cell membrane modification for rapid display of proteins as a novel means of immunomodulation: FasL-decorated cells prevent islet graft rejection
    • Yolcu ES, Askenasy N, Singh NP et al. Cell membrane modification for rapid display of proteins as a novel means of immunomodulation: FasL-decorated cells prevent islet graft rejection. Immunity 2002;17:795-808.
    • (2002) Immunity , vol.17 , pp. 795-808
    • Yolcu, E.S.1    Askenasy, N.2    Singh, N.P.3
  • 118
    • 0025963233 scopus 로고
    • Graft-versus-host disease
    • Ferrara JL, Deeg HJ. Graft-versus-host disease. N Engl J Med 1991;324:667-674.
    • (1991) N Engl J Med , vol.324 , pp. 667-674
    • Ferrara, J.L.1    Deeg, H.J.2
  • 119
    • 0035760863 scopus 로고    scopus 로고
    • The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation
    • Ho VT, Soiffer RJ. The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation. Blood 2001;98:3192-3204.
    • (2001) Blood , vol.98 , pp. 3192-3204
    • Ho, V.T.1    Soiffer, R.J.2
  • 120
    • 0028208561 scopus 로고
    • Control of graft-versus-host disease and graft rejection by T cell depletion of donor and recipient with Campath-1 antibodies: Results of matched sibling transplants for malignant diseases
    • Hale G, Waldmann H. Control of graft-versus-host disease and graft rejection by T cell depletion of donor and recipient with Campath-1 antibodies: results of matched sibling transplants for malignant diseases. Bone Marrow Transplant 1994;13:597-611.
    • (1994) Bone Marrow Transplant , vol.13 , pp. 597-611
    • Hale, G.1    Waldmann, H.2
  • 121
    • 0025127674 scopus 로고
    • T cell depletion with anti-CD5 immunotoxin in histocompatible bone marrow transplantation: The correlation between residual CD5 negative T cells and subsequent graft-versus-host disease
    • Filipovich AH, Vallera D, McGlave P et al. T cell depletion with anti-CD5 immunotoxin in histocompatible bone marrow transplantation: the correlation between residual CD5 negative T cells and subsequent graft-versus-host disease. Transplantation 1990;50:410-415.
    • (1990) Transplantation , vol.50 , pp. 410-415
    • Filipovich, A.H.1    Vallera, D.2    McGlave, P.3
  • 122
    • 0026773113 scopus 로고
    • Prevention of graft-versus-host disease by selective depletion of CD6-positive T lymphocytes from donor bone marrow
    • Soiffer RJ, Murray C, Mauch P et al. Prevention of graft-versus-host disease by selective depletion of CD6-positive T lymphocytes from donor bone marrow. J Clin Oncol 1992;10:1191-1200.
    • (1992) J Clin Oncol , vol.10 , pp. 1191-1200
    • Soiffer, R.J.1    Murray, C.2    Mauch, P.3
  • 123
    • 0030982179 scopus 로고    scopus 로고
    • Effect of T cell subset dose on outcome of T cell-depleted bone marrow transplantation
    • Kawanishi Y, Passweg J, Drobyski WR et al. Effect of T cell subset dose on outcome of T cell-depleted bone marrow transplantation. Bone Marrow Transplant 1997;19:1069-1077.
    • (1997) Bone Marrow Transplant , vol.19 , pp. 1069-1077
    • Kawanishi, Y.1    Passweg, J.2    Drobyski, W.R.3
  • 124
    • 0028125191 scopus 로고
    • Successful engraftment of T-cell-depleted haploidentical "three-loci" incompatible transplants in leukemia patients by addition of recombinant human granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cells to bone marrow inoculum
    • Aversa F, Tabilio A, Terenzi A et al. Successful engraftment of T-cell-depleted haploidentical "three-loci" incompatible transplants in leukemia patients by addition of recombinant human granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cells to bone marrow inoculum. Blood 1994;84:3948-3955.
    • (1994) Blood , vol.84 , pp. 3948-3955
    • Aversa, F.1    Tabilio, A.2    Terenzi, A.3
  • 125
    • 0028789191 scopus 로고
    • Megadose of T cell-depleted bone marrow overcomes MHC barriers in sublethally irradiated mice
    • Bachar-Lustig E,Rachamim N, Li HW et al. Megadose of T cell-depleted bone marrow overcomes MHC barriers in sublethally irradiated mice. Nat Med 1995;1:1268-1273.
    • (1995) Nat Med , vol.1 , pp. 1268-1273
    • Bachar-Lustig, E.1    Rachamim, N.2    Li, H.W.3
  • 126
    • 0036838503 scopus 로고    scopus 로고
    • Transduction of donor hematopoietic stem-progenitor cells with Fas ligand enhanced short-term engraftment in a murine model of allogeneic bone marrow transplantation
    • Whartenby KA, Straley EE, Kim H et al. Transduction of donor hematopoietic stem-progenitor cells with Fas ligand enhanced short-term engraftment in a murine model of allogeneic bone marrow transplantation. Blood 2002;100:3147-3154.
    • (2002) Blood , vol.100 , pp. 3147-3154
    • Whartenby, K.A.1    Straley, E.E.2    Kim, H.3
  • 127
    • 0025855941 scopus 로고
    • Immunologic tolerance to renal allografts after bone marrow transplants from the same donors
    • Sayegh MH, Fine NA, Smith JL et al. Immunologic tolerance to renal allografts after bone marrow transplants from the same donors. Ann Intern Med 1991;114:954-955.
    • (1991) Ann Intern Med , vol.114 , pp. 954-955
    • Sayegh, M.H.1    Fine, N.A.2    Smith, J.L.3
  • 128
    • 0028560026 scopus 로고
    • Renal transplantation without immunosuppression in a host with tolerance induced by allogeneic bone marrow transplantation
    • Helg C, Chapuis B, Bolle JF et al. Renal transplantation without immunosuppression in a host with tolerance induced by allogeneic bone marrow transplantation. Transplantation 1994;58:1420-1422.
    • (1994) Transplantation , vol.58 , pp. 1420-1422
    • Helg, C.1    Chapuis, B.2    Bolle, J.F.3
  • 129
    • 0035875792 scopus 로고    scopus 로고
    • Tolerance in renal transplantation after allogeneic bone marrow transplantation: 6-year follow-up
    • Sellers MT, Deierhoi MH, Curtis JJ et al. Tolerance in renal transplantation after allogeneic bone marrow transplantation: 6-year follow-up. Transplantation 2001;71:1681-1683.
    • (2001) Transplantation , vol.71 , pp. 1681-1683
    • Sellers, M.T.1    Deierhoi, M.H.2    Curtis, J.J.3
  • 130
    • 0031938903 scopus 로고    scopus 로고
    • An essential role for Fas ligand in transplantation tolerance induced by donor bone marrow
    • George JF, Sweeney SD, Kirklin JK et al. An essential role for Fas ligand in transplantation tolerance induced by donor bone marrow. Nat Med 1998;4:333-335.
    • (1998) Nat Med , vol.4 , pp. 333-335
    • George, J.F.1    Sweeney, S.D.2    Kirklin, J.K.3
  • 131
    • 0034805466 scopus 로고    scopus 로고
    • Indefinite allograft survival mediated by donor bone marrow is dependent on the presence of a functional CD95 (Fas) gene in recipients
    • Goldstein DR, Thomas JM, Kirklin JK et al. Indefinite allograft survival mediated by donor bone marrow is dependent on the presence of a functional CD95 (Fas) gene in recipients. J Heart Lung Transplant 2001;20:1132-1135.
    • (2001) J Heart Lung Transplant , vol.20 , pp. 1132-1135
    • Goldstein, D.R.1    Thomas, J.M.2    Kirklin, J.K.3
  • 132
    • 0036514975 scopus 로고    scopus 로고
    • Autoimmune thyroid disease: New models of cell death in autoimmunity
    • Stassi G, De Maria R. Autoimmune thyroid disease: new models of cell death in autoimmunity. Nat Rev Immunol 2002;2:195-204.
    • (2002) Nat Rev Immunol , vol.2 , pp. 195-204
    • Stassi, G.1    De Maria, R.2
  • 133
    • 0034651608 scopus 로고    scopus 로고
    • Transgenic expression of Fas ligand on thyroid follicular cells prevents autoimmune thyroiditis
    • Batteux F, Lores P, Bucchini D et al. Transgenic expression of Fas ligand on thyroid follicular cells prevents autoimmune thyroiditis. J Immunol 2000;164:1681-1688.
    • (2000) J Immunol , vol.164 , pp. 1681-1688
    • Batteux, F.1    Lores, P.2    Bucchini, D.3
  • 134
    • 2142662186 scopus 로고    scopus 로고
    • Multiple sclerosis
    • Hafler DA. Multiple sclerosis. J Clin Invest 2004;113:788-794.
    • (2004) J Clin Invest , vol.113 , pp. 788-794
    • Hafler, D.A.1
  • 135
    • 0033978459 scopus 로고    scopus 로고
    • Animal models for autoimmune demyelinating disorders of the nervous system
    • Gold R, Hartung HP, Toyka KV. Animal models for autoimmune demyelinating disorders of the nervous system. Mol Med Today 2000;6:88-91.
    • (2000) Mol Med Today , vol.6 , pp. 88-91
    • Gold, R.1    Hartung, H.P.2    Toyka, K.V.3
  • 136
    • 0036681781 scopus 로고    scopus 로고
    • Intrathecal Fas ligand infusion strengthens immunoprivilege of central nervous system and suppresses experimental autoimmune encephalomyelitis
    • Zhu B, Luo L, Chen Y et al. Intrathecal Fas ligand infusion strengthens immunoprivilege of central nervous system and suppresses experimental autoimmune encephalomyelitis. J Immunol 2002;169:1561-1569.
    • (2002) J Immunol , vol.169 , pp. 1561-1569
    • Zhu, B.1    Luo, L.2    Chen, Y.3
  • 137
    • 0038011833 scopus 로고    scopus 로고
    • Evolving concepts of rheumatoid arthritis
    • Firestein GS. Evolving concepts of rheumatoid arthritis. Nature 2003;423:356-361.
    • (2003) Nature , vol.423 , pp. 356-361
    • Firestein, G.S.1
  • 138
    • 0036484325 scopus 로고    scopus 로고
    • The molecular pathogenesis of collagen-induced arthritis in mice: A model for rheumatoid arthritis
    • Holmdahl R, Bockermann R, Backlund J et al. The molecular pathogenesis of collagen-induced arthritis in mice: a model for rheumatoid arthritis. Ageing Res Rev 2002;1:135-147.
    • (2002) Ageing Res Rev , vol.1 , pp. 135-147
    • Holmdahl, R.1    Bockermann, R.2    Backlund, J.3
  • 139
    • 0037090276 scopus 로고    scopus 로고
    • Depletion of collagen II-reactive T cells and blocking of B cell activation prevents collagen II-induced arthritis in DBA/1j mice
    • Zhang HG, Yang P, Xie J et al. Depletion of collagen II-reactive T cells and blocking of B cell activation prevents collagen II-induced arthritis in DBA/1j mice. J Immunol 2002;168:4164-4172.
    • (2002) J Immunol , vol.168 , pp. 4164-4172
    • Zhang, H.G.1    Yang, P.2    Xie, J.3
  • 140
    • 18044400416 scopus 로고    scopus 로고
    • Defective Fas ligand-mediated apoptosis predisposes to development of a chronic erosive arthritis subsequent to Mycoplasma pulmonis infection
    • Hsu HC, Zhang HG, Song GG et al. Defective Fas ligand-mediated apoptosis predisposes to development of a chronic erosive arthritis subsequent to Mycoplasma pulmonis infection. Arthritis Rheum 2001;44:2146-2159.
    • (2001) Arthritis Rheum , vol.44 , pp. 2146-2159
    • Hsu, H.C.1    Zhang, H.G.2    Song, G.G.3
  • 141
    • 0036158217 scopus 로고    scopus 로고
    • Myasthenia gravis
    • Nicolle MW. Myasthenia gravis. Neurologist 2002;8:2-21.
    • (2002) Neurologist , vol.8 , pp. 2-21
    • Nicolle, M.W.1
  • 142
    • 0034237433 scopus 로고    scopus 로고
    • Targeting antigen-specific T cells by genetically engineered antigen presenting cells: A strategy for specific immunotherapy of autoimmune disease
    • Wu JM, Wu B, Guarnieri F et al. Targeting antigen-specific T cells by genetically engineered antigen presenting cells: a strategy for specific immunotherapy of autoimmune disease. J Neuroimmunol 2000;106:145-153.
    • (2000) J Neuroimmunol , vol.106 , pp. 145-153
    • Wu, J.M.1    Wu, B.2    Guarnieri, F.3
  • 143
    • 0035313457 scopus 로고    scopus 로고
    • Specific immunotherapy by genetically engineered APCs: The "guided missile" strategy
    • Wu B, Wu JM, Miagkov A et al. Specific immunotherapy by genetically engineered APCs: the "guided missile" strategy. J Immunol 2001;166:4773-4779.
    • (2001) J Immunol , vol.166 , pp. 4773-4779
    • Wu, B.1    Wu, J.M.2    Miagkov, A.3
  • 144
    • 0043247144 scopus 로고    scopus 로고
    • Specific immunotherapy of experimental myasthenia by genetically engineered APCs: The "guided missile" strategy
    • Drachman DB, Wu JM, Miagkov A et al. Specific immunotherapy of experimental myasthenia by genetically engineered APCs: the "guided missile" strategy. Ann N Y Acad Sci 2003;998:520-532.
    • (2003) Ann N Y Acad Sci , vol.998 , pp. 520-532
    • Drachman, D.B.1    Wu, J.M.2    Miagkov, A.3
  • 146
    • 0032433666 scopus 로고    scopus 로고
    • Murine cytomegalovirus induces a Sjogren's syndrome-like disease in C57B1/6-lpr/lpr mice
    • Fleck M, Kern ER, Zhou T et al. Murine cytomegalovirus induces a Sjogren's syndrome-like disease in C57B1/6-lpr/lpr mice. Arthritis Rheum 1998;41:2175-2184.
    • (1998) Arthritis Rheum , vol.41 , pp. 2175-2184
    • Fleck, M.1    Kern, E.R.2    Zhou, T.3
  • 147
    • 0035052164 scopus 로고    scopus 로고
    • Treatment of chronic sialadenitis in a murine model of Sjogren's syndrome by local fasL gene transfer
    • Fleck M, Zhang HG, Kern ER et al. Treatment of chronic sialadenitis in a murine model of Sjogren's syndrome by local fasL gene transfer. Arthritis Rheum 2001;44:964-973.
    • (2001) Arthritis Rheum , vol.44 , pp. 964-973
    • Fleck, M.1    Zhang, H.G.2    Kern, E.R.3
  • 148
    • 0035838979 scopus 로고    scopus 로고
    • Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity
    • Liu YJ. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell 2001;106:259-262.
    • (2001) Cell , vol.106 , pp. 259-262
    • Liu, Y.J.1
  • 149
    • 0037769110 scopus 로고    scopus 로고
    • Dendritic cells in immunity and tolerance: Do they display opposite functions?
    • Moser M. Dendritic cells in immunity and tolerance: do they display opposite functions? Immunity 2003;19:5-8.
    • (2003) Immunity , vol.19 , pp. 5-8
    • Moser, M.1
  • 150
    • 0036715411 scopus 로고    scopus 로고
    • Immature, semi-mature and fully mature dendritic cells: Which signals induce tolerance or immunity?
    • Lutz MB, Schuler G. Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol 2002;23:445-449.
    • (2002) Trends Immunol , vol.23 , pp. 445-449
    • Lutz, M.B.1    Schuler, G.2
  • 151
    • 0037565445 scopus 로고    scopus 로고
    • Dendritic cell function in vivo during the steady state: A role in peripheral tolerance
    • Steinman RM, Hawiger D, Liu K et al. Dendritic cell function in vivo during the steady state: a role in peripheral tolerance. Ann N Y Acad Sci 2003;987:15-25.
    • (2003) Ann N Y Acad Sci , vol.987 , pp. 15-25
    • Steinman, R.M.1    Hawiger, D.2    Liu, K.3
  • 152
    • 0036378101 scopus 로고    scopus 로고
    • Immature, but not inactive: The tolerogenic function of immature dendritic cells
    • Mahnke K, Schmitt E, Bonifay L et al. Immature, but not inactive: the tolerogenic function of immature dendritic cells. Immunol Cell Biol 2002;80:477-483.
    • (2002) Immunol Cell Biol , vol.80 , pp. 477-483
    • Mahnke, K.1    Schmitt, E.2    Bonifay, L.3
  • 153
    • 0344440959 scopus 로고    scopus 로고
    • Induction of tolerogenic DCs: 'You are what you eat'
    • Mahnke K, Knops J, Ink AH. Induction of tolerogenic DCs: 'you are what you eat.' Trends Immunol 2003;24:646-651.
    • (2003) Trends Immunol , vol.24 , pp. 646-651
    • Mahnke, K.1    Knops, J.2    Ink, A.H.3
  • 154
    • 0141742285 scopus 로고    scopus 로고
    • Dendritic cells in peripheral tolerance and immunity
    • Gad M, Caisson MH, Pedersen AE. Dendritic cells in peripheral tolerance and immunity. APMIS 2003;111:766-775.
    • (2003) APMIS , vol.111 , pp. 766-775
    • Gad, M.1    Caisson, M.H.2    Pedersen, A.E.3
  • 156
    • 0035903326 scopus 로고    scopus 로고
    • Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
    • Hawiger D, Indaba K, Dorsett Y et al. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med 2001;194:769-779.
    • (2001) J Exp Med , vol.194 , pp. 769-779
    • Hawiger, D.1    Indaba, K.2    Dorsett, Y.3
  • 157
    • 0036659913 scopus 로고    scopus 로고
    • Antigen-bearing immature dendritic cells induce peptide-specific CD8+ regulatory T cells in vivo in humans
    • Dhodapkar MV, Steinman RM. Antigen-bearing immature dendritic cells induce peptide-specific CD8+ regulatory T cells in vivo in humans. Blood 2002;100:174-177.
    • (2002) Blood , vol.100 , pp. 174-177
    • Dhodapkar, M.V.1    Steinman, R.M.2
  • 158
    • 0037987977 scopus 로고    scopus 로고
    • Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo
    • Wakkach A, Fournier N, Brun V et al. Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity 2003;18:605-617.
    • (2003) Immunity , vol.18 , pp. 605-617
    • Wakkach, A.1    Fournier, N.2    Brun, V.3
  • 159
    • 18544364477 scopus 로고    scopus 로고
    • Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase
    • Munn DH, Sharma MD, Lee JR et al. Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase. Science 2002;297:1867-1870.
    • (2002) Science , vol.297 , pp. 1867-1870
    • Munn, D.H.1    Sharma, M.D.2    Lee, J.R.3
  • 160
    • 0036297943 scopus 로고    scopus 로고
    • Tolerogenic antigen-presenting cells
    • Munn DH. Tolerogenic antigen-presenting cells. Ann NY Acad Sci 2002;961:343-345.
    • (2002) Ann NY Acad Sci , vol.961 , pp. 343-345
    • Munn, D.H.1
  • 161
    • 0036122891 scopus 로고    scopus 로고
    • Tolerization of dendritic cells by T(S) cells: The crucial role of inhibitory receptors ILT3 and ILT4
    • Chang CC, Ciubotariu R, Manavalan JS et al. Tolerization of dendritic cells by T(S) cells: the crucial role of inhibitory receptors ILT3 and ILT4. Nat Immunol 2002;3:237-243.
    • (2002) Nat Immunol , vol.3 , pp. 237-243
    • Chang, C.C.1    Ciubotariu, R.2    Manavalan, J.S.3
  • 162
    • 0141629858 scopus 로고    scopus 로고
    • High expression of ILT3 and ILT4 is a general feature of tolerogenic dendritic cells
    • Manavalan JS, Rossi PC, Vlad G et al. High expression of ILT3 and ILT4 is a general feature of tolerogenic dendritic cells. Transpl Immunol 2003;11:245-258.
    • (2003) Transpl Immunol , vol.11 , pp. 245-258
    • Manavalan, J.S.1    Rossi, P.C.2    Vlad, G.3
  • 163
    • 0034327258 scopus 로고    scopus 로고
    • Receptor engagement on cells expressing a ligand for the tolerance-inducing molecule OX2 induces an immunoregulatory population that inhibits alloreactivity in vitro and in vivo
    • Gorczynski RM, Yu K, Clark D. Receptor engagement on cells expressing a ligand for the tolerance-inducing molecule OX2 induces an immunoregulatory population that inhibits alloreactivity in vitro and in vivo. J Immunol 2000;165:4854-4860.
    • (2000) J Immunol , vol.165 , pp. 4854-4860
    • Gorczynski, R.M.1    Yu, K.2    Clark, D.3
  • 164
    • 0037080938 scopus 로고    scopus 로고
    • Manipulation of dendritic cells for tolerance induction in transplantation and autoimmune disease
    • Lu L, Thomson AW. Manipulation of dendritic cells for tolerance induction in transplantation and autoimmune disease. Transplantation 2002;73:S19-S22.
    • (2002) Transplantation , vol.73
    • Lu, L.1    Thomson, A.W.2
  • 165
    • 0038047128 scopus 로고    scopus 로고
    • Dendritic cells, T cell tolerance and therapy of adverse immune reactions
    • Morel PA, Feili-Hariri M, Coates PT et al. Dendritic cells, T cell tolerance and therapy of adverse immune reactions. Clin Exp Immunol 2003;133:1-10.
    • (2003) Clin Exp Immunol , vol.133 , pp. 1-10
    • Morel, P.A.1    Feili-Hariri, M.2    Coates, P.T.3
  • 166
    • 0141853307 scopus 로고    scopus 로고
    • Prevention of allograft rejection by in vitro generated tolerogenic dendritic cells
    • Ichim TE, Zhong R, Min WP. Prevention of allograft rejection by in vitro generated tolerogenic dendritic cells. Transpl Immunol 2003;11:295-306.
    • (2003) Transpl Immunol , vol.11 , pp. 295-306
    • Ichim, T.E.1    Zhong, R.2    Min, W.P.3
  • 167
    • 0032790004 scopus 로고    scopus 로고
    • Induction of antigen-specific immunosuppression by CD95L cDNA-transfected 'killer' dendritic cells
    • Matsue H, Matsue K, Walters M et al. Induction of antigen-specific immunosuppression by CD95L cDNA-transfected 'killer' dendritic cells. Nat Med 1999;5:930-937.
    • (1999) Nat Med , vol.5 , pp. 930-937
    • Matsue, H.1    Matsue, K.2    Walters, M.3
  • 168
    • 0035761417 scopus 로고    scopus 로고
    • Immunosuppressive properties of CD95L-transduced "killer" hybrids created by fusing donor- and recipient-derived dendritic cells
    • Matsue H, Matsue K, Kusuhara M et al. Immunosuppressive properties of CD95L-transduced "killer" hybrids created by fusing donor- and recipient-derived dendritic cells. Blood 2001;98:3465-3472.
    • (2001) Blood , vol.98 , pp. 3465-3472
    • Matsue, H.1    Matsue, K.2    Kusuhara, M.3
  • 169
    • 0038528547 scopus 로고    scopus 로고
    • Mature but not immature Fas ligand (CD95L)-transduced human monocyte-derived dendritic cells are protected from Fas-mediated apoptosis and can be used as killer APC
    • Hoves S, Krause SW, Halbritter D et al. Mature but not immature Fas ligand (CD95L)-transduced human monocyte-derived dendritic cells are protected from Fas-mediated apoptosis and can be used as killer APC. J Immunol 2003;170:5406-5413.
    • (2003) J Immunol , vol.170 , pp. 5406-5413
    • Hoves, S.1    Krause, S.W.2    Halbritter, D.3
  • 170
    • 0034210209 scopus 로고    scopus 로고
    • Expression of C-FLIP(L) and resistance to CD95-mediated apoptosis of monocyte-derived dendritic cells: Inhibition by bisindolylmaleimide
    • Willems F, Amraoui Z, Vanderheyde N et al. Expression of C-FLIP(L) and resistance to CD95-mediated apoptosis of monocyte-derived dendritic cells: inhibition by bisindolylmaleimide. Blood 2000;95:3478-3482.
    • (2000) Blood , vol.95 , pp. 3478-3482
    • Willems, F.1    Amraoui, Z.2    Vanderheyde, N.3
  • 171
    • 0036213358 scopus 로고    scopus 로고
    • Mature dendritic cells are protected from Fas/CD95-mediated apoptosis by upregulation of Bcl-X(L)
    • Lundqvist A, Nagata T, Kiessling R et al. Mature dendritic cells are protected from Fas/CD95-mediated apoptosis by upregulation of Bcl-X(L). Cancer Immunol Immunother 2002;51:139-144.
    • (2002) Cancer Immunol Immunother , vol.51 , pp. 139-144
    • Lundqvist, A.1    Nagata, T.2    Kiessling, R.3
  • 173
    • 1942454394 scopus 로고    scopus 로고
    • + T cells by Fas ligand (FasL/CD95L)-expressing killer-dendritic cells
    • + T cells by Fas ligand (FasL/CD95L)-expressing killer-dendritic cells. Immunobiology 2004;208:463-475.
    • (2004) Immunobiology , vol.208 , pp. 463-475
    • Hoves, S.1    Krause, S.W.2    Herfarth, H.3
  • 174
    • 0033082545 scopus 로고    scopus 로고
    • Induction of specific T cell tolerance by Fas ligand-expressing antigen-presenting cells
    • Zhang HG, Su X, Liu D et al. Induction of specific T cell tolerance by Fas ligand-expressing antigen-presenting cells. J Immunol 1999;162:1423-1430.
    • (1999) J Immunol , vol.162 , pp. 1423-1430
    • Zhang, H.G.1    Su, X.2    Liu, D.3
  • 175
    • 0036080346 scopus 로고    scopus 로고
    • B cells engineered to express Fas ligand suppress pre-sensitized antigen-specific T cell responses in vivo
    • Kosiewicz MM, Krishnan A, Worthington MT et al. B cells engineered to express Fas ligand suppress pre-sensitized antigen-specific T cell responses in vivo. Eur J Immunol 2002;32:1679-1687.
    • (2002) Eur J Immunol , vol.32 , pp. 1679-1687
    • Kosiewicz, M.M.1    Krishnan, A.2    Worthington, M.T.3
  • 176
    • 0034630459 scopus 로고    scopus 로고
    • Antigen-specific induction of peripheral T cell tolerance in vivo by codelivery of DNA vectors encoding antigen and Fas ligand
    • Georgantas RW 3rd, Leong KW, August JT. Antigen-specific induction of peripheral T cell tolerance in vivo by codelivery of DNA vectors encoding antigen and Fas ligand. Hum Gene Ther 2000;11:851-858.
    • (2000) Hum Gene Ther , vol.11 , pp. 851-858
    • Georgantas III, R.W.1    Leong, K.W.2    August, J.T.3
  • 177
    • 0037080564 scopus 로고    scopus 로고
    • Dendritic cells transduced with viral interleukin 10 or Fas ligand: No evidence for induction of allotolerance in vivo
    • Buonocore S, Van Meirvenne S, Demoor FX et al. Dendritic cells transduced with viral interleukin 10 or Fas ligand: no evidence for induction of allotolerance in vivo. Transplantation 2002;73:S27-S30.
    • (2002) Transplantation , vol.73
    • Buonocore, S.1    Van Meirvenne, S.2    Demoor, F.X.3
  • 178
    • 0037441897 scopus 로고    scopus 로고
    • Dendritic cells overexpressing CD95 (Fas) ligand elicit vigorous allospecific T-cell responses in vivo
    • Buonocore S, Paulart F, Le Moine A et al. Dendritic cells overexpressing CD95 (Fas) ligand elicit vigorous allospecific T-cell responses in vivo. Blood 2003;101:1469-1476.
    • (2003) Blood , vol.101 , pp. 1469-1476
    • Buonocore, S.1    Paulart, F.2    Le Moine, A.3
  • 179
    • 0027291205 scopus 로고
    • Lethal effect of the anti-Fas antibody in mice
    • Ogasawara J, Watanabe-Fukunaga R, AdachiM et al. Lethal effect of the anti-Fas antibody in mice. Nature 1993;364:806-809.
    • (1993) Nature , vol.364 , pp. 806-809
    • Ogasawara, J.1    Watanabe-Fukunaga, R.2    Adachi, M.3
  • 180
    • 0029096804 scopus 로고
    • Local Fas/APO-1 (CD95) ligand-mediated tumor cell killing in vivo
    • Rensing-Ehl A, Frei K, Flury R et al. Local Fas/APO-1 (CD95) ligand-mediated tumor cell killing in vivo. Eur J Immunol 1995;25:2253-2258.
    • (1995) Eur J Immunol , vol.25 , pp. 2253-2258
    • Rensing-Ehl, A.1    Frei, K.2    Flury, R.3
  • 181
    • 0033032347 scopus 로고    scopus 로고
    • Neuronal and glial cell type-specific promoters within adenovirus recombinants restrict the expression of the apoptosis-inducing molecule Fas ligand to predetermined brain cell types, and abolish peripheral liver toxicity
    • Morelli AE, Larregina AT, Smith-Arica J et al. Neuronal and glial cell type-specific promoters within adenovirus recombinants restrict the expression of the apoptosis-inducing molecule Fas ligand to predetermined brain cell types, and abolish peripheral liver toxicity. J Gen Virol 1999;80(Pt 3):571-583.
    • (1999) J Gen Virol , vol.80 , Issue.PART 3 , pp. 571-583
    • Morelli, A.E.1    Larregina, A.T.2    Smith-Arica, J.3
  • 182
    • 0031666610 scopus 로고    scopus 로고
    • Efficient Fas-ligand gene expression in rodent liver after intravenous injection of a recombinant adenovirus by the use of a Cre-mediated switching system
    • Okuyama T, Fujino M, Li XK et al. Efficient Fas-ligand gene expression in rodent liver after intravenous injection of a recombinant adenovirus by the use of a Cre-mediated switching system. Gene Ther 1998;5:1047-1053.
    • (1998) Gene Ther , vol.5 , pp. 1047-1053
    • Okuyama, T.1    Fujino, M.2    Li, X.K.3
  • 183
    • 0034124055 scopus 로고    scopus 로고
    • Adenoviral vector which delivers FasL-GFP fusion protein regulated by the tet-inducible expression system
    • Rubinchik S, Ding R, Qiu AJ et al. Adenoviral vector which delivers FasL-GFP fusion protein regulated by the tet-inducible expression system. Gene Ther 2000;7:875-885.
    • (2000) Gene Ther , vol.7 , pp. 875-885
    • Rubinchik, S.1    Ding, R.2    Qiu, A.J.3
  • 184
    • 0036209678 scopus 로고    scopus 로고
    • Spatial and temporal control of transgene expression through ultrasound-mediated induction of the heat shock protein 70B promoter in vivo
    • Smith RC, Machluf M, Bromley P et al. Spatial and temporal control of transgene expression through ultrasound-mediated induction of the heat shock protein 70B promoter in vivo. Hum Gene Ther 2002;13:697-706.
    • (2002) Hum Gene Ther , vol.13 , pp. 697-706
    • Smith, R.C.1    Machluf, M.2    Bromley, P.3
  • 185
    • 0036035697 scopus 로고    scopus 로고
    • Non-cleavable mutant Fas ligand transfection of donor cornea abrogates ocular immune privilege
    • Sano Y, Yamada J, Ishino Y et al. Non-cleavable mutant Fas ligand transfection of donor cornea abrogates ocular immune privilege. Exp Eye Res 2002;75:475-483.
    • (2002) Exp Eye Res , vol.75 , pp. 475-483
    • Sano, Y.1    Yamada, J.2    Ishino, Y.3
  • 186
    • 0036721807 scopus 로고    scopus 로고
    • Membrane Fas ligand activates innate immunity and terminates ocular immune privilege
    • Gregory MS, Repp AC, Holhbaum AM et al. Membrane Fas ligand activates innate immunity and terminates ocular immune privilege. J Immunol 2002;169:2727-2735.
    • (2002) J Immunol , vol.169 , pp. 2727-2735
    • Gregory, M.S.1    Repp, A.C.2    Holhbaum, A.M.3
  • 187
    • 0031570932 scopus 로고    scopus 로고
    • Increased lymphocyte apoptosis in Fas ligand transgenic mice
    • Cheng J, Liu C, Yang P et al. Increased lymphocyte apoptosis in Fas ligand transgenic mice. J Immunol 1997;159:674-684.
    • (1997) J Immunol , vol.159 , pp. 674-684
    • Cheng, J.1    Liu, C.2    Yang, P.3
  • 188
    • 0033456158 scopus 로고    scopus 로고
    • FLICE-inhibitory protein expression during macrophage differentiation confers resistance to fas-mediated apoptosis
    • Perlman H, Pagliari LJ, Georganas C et al. FLICE-inhibitory protein expression during macrophage differentiation confers resistance to fas-mediated apoptosis. J Exp Med 1999;190:1679-1688.
    • (1999) J Exp Med , vol.190 , pp. 1679-1688
    • Perlman, H.1    Pagliari, L.J.2    Georganas, C.3
  • 189
    • 0033989612 scopus 로고    scopus 로고
    • Inhibition of Fas-mediated apoptosis by the B cell antigen receptor through c-FLIP
    • Wang J, Lobito AA, Shen F et al. Inhibition of Fas-mediated apoptosis by the B cell antigen receptor through c-FLIP. Eur J Immunol 2000;30:155-163.
    • (2000) Eur J Immunol , vol.30 , pp. 155-163
    • Wang, J.1    Lobito, A.A.2    Shen, F.3
  • 190
    • 0036224923 scopus 로고    scopus 로고
    • Bcl-2, Bcl-xL and c-FLIP(L) potentially regulate the susceptibility of human peripheral blood monocyte-derived dendritic cells to cell death at different developmental stages
    • Hasebe H, Sato K, Yanagie H et al. Bcl-2, Bcl-xL and c-FLIP(L) potentially regulate the susceptibility of human peripheral blood monocyte-derived dendritic cells to cell death at different developmental stages. Biomed Pharmacother 2002;56:144-151.
    • (2002) Biomed Pharmacother , vol.56 , pp. 144-151
    • Hasebe, H.1    Sato, K.2    Yanagie, H.3
  • 191
    • 0028804157 scopus 로고
    • Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-alpha and ligation of Fas antigen
    • Abreu-Martin MT, Vidrich A, Lynch DH et al. Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-alpha and ligation of Fas antigen. J Immunol 1995;155:4147-4154.
    • (1995) J Immunol , vol.155 , pp. 4147-4154
    • Abreu-Martin, M.T.1    Vidrich, A.2    Lynch, D.H.3
  • 192
    • 0031730436 scopus 로고    scopus 로고
    • Caspase 1-independent IL-1β release and inflammation induced by the apoptosis inducer Fas ligand
    • Miwa K, Asano M, Horai R et al. Caspase 1-independent IL-1β release and inflammation induced by the apoptosis inducer Fas ligand. Nat Med 1998;4:1287-1292.
    • (1998) Nat Med , vol.4 , pp. 1287-1292
    • Miwa, K.1    Asano, M.2    Horai, R.3
  • 193
    • 0033929291 scopus 로고    scopus 로고
    • Fas/FADD-mediated activation of a specific program of inflammatory gene expression in vascular smooth muscle cells
    • Schaub FJ, Han DK, Liles WC et al. Fas/FADD-mediated activation of a specific program of inflammatory gene expression in vascular smooth muscle cells. Nat Med 2000;6:790-796.
    • (2000) Nat Med , vol.6 , pp. 790-796
    • Schaub, F.J.1    Han, D.K.2    Liles, W.C.3
  • 194
    • 0034600068 scopus 로고    scopus 로고
    • Opposing effects of transmembrane and soluble Fas ligand expression on inflammation and tumor cell survival
    • Hohlbaum AM, Moe S, Marshak-Rothstein A. Opposing effects of transmembrane and soluble Fas ligand expression on inflammation and tumor cell survival. J Exp Med 2000;191:1209-1220.
    • (2000) J Exp Med , vol.191 , pp. 1209-1220
    • Hohlbaum, A.M.1    Moe, S.2    Marshak-Rothstein, A.3
  • 195
    • 0026571065 scopus 로고
    • Studies on the induction of anterior chamber-associated immune deviation (ACAID): III. Induction of ACAID depends upon intraocular transforming growth factor-beta
    • Wilbanks GA, Mammolenti M, Streilein JW. Studies on the induction of anterior chamber-associated immune deviation (ACAID): III. Induction of ACAID depends upon intraocular transforming growth factor-beta. Eur J Immunol 1992;22:165-173.
    • (1992) Eur J Immunol , vol.22 , pp. 165-173
    • Wilbanks, G.A.1    Mammolenti, M.2    Streilein, J.W.3
  • 196
    • 0028081210 scopus 로고
    • The presence of biologically significant concentrations of glucocorticoids but little or no cortisol binding globulin within aqueous humor: Relevance to immune privilege in the anterior chamber of the eye
    • Knisely TL, Hosoi J, Nazareno R et al. The presence of biologically significant concentrations of glucocorticoids but little or no cortisol binding globulin within aqueous humor: relevance to immune privilege in the anterior chamber of the eye. Invest Ophthalmol Vis Sci 1994;35:3711-3723.
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , pp. 3711-3723
    • Knisely, T.L.1    Hosoi, J.2    Nazareno, R.3
  • 197
    • 0028361144 scopus 로고
    • Immunoreactive vasoactive intestinal peptide contributes to the immunosuppressive activity of normal aqueous humor
    • Taylor AW, Streilein JW, Cousins SW. Immunoreactive vasoactive intestinal peptide contributes to the immunosuppressive activity of normal aqueous humor. J Immunol 1994:153:1080-1086.
    • (1994) J Immunol , vol.153 , pp. 1080-1086
    • Taylor, A.W.1    Streilein, J.W.2    Cousins, S.W.3
  • 198
    • 0032573581 scopus 로고    scopus 로고
    • Regulation of the proinflammatory effects of Fas ligand (CD95L)
    • Chen JJ, Sun Y, Nabel GJ. Regulation of the proinflammatory effects of Fas ligand (CD95L). Science 1998;282:1714-1717.
    • (1998) Science , vol.282 , pp. 1714-1717
    • Chen, J.J.1    Sun, Y.2    Nabel, G.J.3
  • 199
    • 0037298345 scopus 로고    scopus 로고
    • Dual response to Fas ligation in human endothelial cells: Apoptosis and induction of chemokines, interleukin-8 and monocyte chemoattractant protein-1
    • Yamaoka-Tojo M, Yamaguchi S, Nitobe J et al. Dual response to Fas ligation in human endothelial cells: apoptosis and induction of chemokines, interleukin-8 and monocyte chemoattractant protein-1. Coron Artery Dis 2003;14:89-94.
    • (2003) Coron Artery Dis , vol.14 , pp. 89-94
    • Yamaoka-Tojo, M.1    Yamaguchi, S.2    Nitobe, J.3
  • 200
    • 0032550366 scopus 로고    scopus 로고
    • Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity
    • Schneider P, Holler N, Bodmer JL et al. Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity. J Exp Med 1998;187:1205-1213.
    • (1998) J Exp Med , vol.187 , pp. 1205-1213
    • Schneider, P.1    Holler, N.2    Bodmer, J.L.3
  • 201
    • 0034850864 scopus 로고    scopus 로고
    • The membrane-bound but not the soluble form of human Fas ligand is responsible for its inflammatory activity
    • Shudo K, Kinoshita K, Imamura R et al. The membrane-bound but not the soluble form of human Fas ligand is responsible for its inflammatory activity. Eur J Immunol 2001;31:2504-2511.
    • (2001) Eur J Immunol , vol.31 , pp. 2504-2511
    • Shudo, K.1    Kinoshita, K.2    Imamura, R.3
  • 202
    • 0030864939 scopus 로고    scopus 로고
    • Transplantation of CD95 ligand-expressing grafts: Influence of transplantation site and difficulty in protecting allo- and xenografts
    • Seino K, Kayagaki N, Tsukada N et al. Transplantation of CD95 ligand-expressing grafts: influence of transplantation site and difficulty in protecting allo- and xenografts. Transplantation 1997;64:1050-1054.
    • (1997) Transplantation , vol.64 , pp. 1050-1054
    • Seino, K.1    Kayagaki, N.2    Tsukada, N.3
  • 204
    • 0037846483 scopus 로고    scopus 로고
    • Pharmacologic, biologic, and genetic engineering approaches to potentiation of donor-derived dendritic cell tolerogenicity
    • Coates PT, Colvin BL, Kaneko K et al. Pharmacologic, biologic, and genetic engineering approaches to potentiation of donor-derived dendritic cell tolerogenicity. Transplantation 2003;75:32S-36S.
    • (2003) Transplantation , vol.75
    • Coates, P.T.1    Colvin, B.L.2    Kaneko, K.3
  • 205
    • 0038723556 scopus 로고    scopus 로고
    • Tolerance and the "Holy Grail" of transplantation
    • Schroeder RA, Marroquin CE, Kuo PC. Tolerance and the "Holy Grail" of transplantation. J Surg Res 2003;111:109-119.
    • (2003) J Surg Res , vol.111 , pp. 109-119
    • Schroeder, R.A.1    Marroquin, C.E.2    Kuo, P.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.