Depletion of collagen II-reactive T cells and blocking of B cell activation prevents collagen II-induced arthritis in DBA/1j mice

Journal of Immunology

Volumn 168, Issue 8, 2002, Pages 4164-4172

  Zhang, Huang Ge ^a   Yang, PingAr ^a   Xie, Jinfu ^a   Liu, Zhongyu ^a   Liu, Di ^a   Xiu, Liang ^a   Zhou, Tong ^a   Wang, Yongming ^a   Hsu, Hui Chen ^a   Mountz, John D ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; COLLAGEN TYPE 2; DOXYCYCLINE; FAS LIGAND; OVALBUMIN; PROTEIN P35;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; B LYMPHOCYTE ACTIVATION; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; IMMUNOPATHOGENESIS; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION;

EID: 0037090276     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.8.4164     Document Type: Article

References (45)

1. Prospects for autoimmune disease: Research advances in rheumatoid arthritis
2. Physiology of cytokine pathways in rheumatoid arthritis
3. Targeting the T cell receptor in rheumatoid arthritis
4. Effector function of resting T cells: Activation of synovial fibroblasts
5. Role of cytokines in rheumatoid arthritis
6. Antineutrophil cytoplasmic Abs in patients with early rheumatoid arthritis: An early marker of progressive erosive disease
7. T and B cell-dependent pathways in rheumatoid arthritis
8. Nature and specificity of the immune response to collagen in type II collagen-induced arthritis in mice
9. Origin of the autoreactive anti-type II collagen response. II. Specificities, Ab isotypes and usage of V gene families of anti-type II collagen B cells
10. B cell-deficient mice do not develop type II collagen-induced arthritis (CIA)
11. Identification of a major antigenic epitope on CNBr-fragment II of type II collagen recognized by murine autoreactive B cells
12. Induction of arthritis with monoclonal antibodies to collagen
13. + T cells
14. Mice lacking mature T and B lymphocytes develop arthritic lesions after immunization with type II collagen
15. Murine T cells reactive to type 11 collagen. II. Functional characterization
16. Characterization of a tolerogenic T cell epitope of type II collagen and its relevance to collagen-induced arthritis
17. Antigen-specific T cell-mediated gene therapy in collagen-induced arthritis
18. + T cells from collagen-induced arthritic mice are essential to transfer arthritis into severe combined immunodeficient mice
19. Identification of T cell determinants on human type II collagen recognized by HLA-DQ8 and HLA-DQ6 transgenic mice
20. Induction of specific T-cell tolerance by adenovirus-transfected, Fas ligand-producing antigen presenting cells
21. Application of a Fas ligand encoding a recombinant adenovirus vector for prolongation of transgene expression
22. Treatment of chronic sialadenitis in a murine model of Sjogren's syndrome by local fasL gene transfer
23. Apoptosis and rheumatoid arthritis: Past, present, and future directions
24. Antigen presenting cells expressing Fas ligand down-modulate chronic inflammatory disease in Fas ligand-deficient mice
25. Induction of specific T cell tolerance by Fas ligand-expressing antigen-presenting cells
26. APRIL and TALL-I and receptors BCMA and TACI: System for regulating humoral immunity
27. BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF
28. BLyS: Member of the tumor necrosis factor family and B lymphocyte stimulator
29. Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI
30. TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice
31. A simplified system for generating recombinant adenoviruses
32. Adeno-associated virus production of soluble tumor necrosis factor receptor neutralizes tumor necrosis factor α and reduces arthritis
33. Gene therapy that inhibits nuclear translocation of nuclear factor κB results in tumor necrosis factor α-induced apoptosis of human synovial fibroblasts
34. Switching transgene expression in the brain using an adenoviral tetracycline-regulatable system
35. Tet repressor-based system for regulated gene expression in eukaryotic cells: Principles and advances
36. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
37. Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule
38. Transcriptional activation by tetracyclines in mammalian cells
39. The baculovirus p35 protein inhibits Fas- and tumor necrosis factor-induced apoptosis
40. Baculovirus-based genetic screen for antiapoptotic genes identifies a novel IAP
41. Control of erythropoietin delivery by doxycycline in mice after intramuscular injection of adeno-associated vector
42. Defective Fas ligand-mediated apoptosis predisposes to development of a chronic erosive arthritis subsequent to Mycoplasma pulmonis infection
43. Light-based imaging of green fluorescent protein-positive ovarian cancer xenografts during therapy
44. Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles
45. Severe B cell hyperplasia and auto-immune disease in TALL-1 transgenic mice