Fas/FADD-mediated activation of a specific program of inflammatory gene expression in vascular smooth muscle cells

Nature Medicine

Volumn 6, Issue 7, 2000, Pages 790-796

  Schaub, Friedemann J ^a   Han, David K M ^a   Liles, W Conrad ^a   Adams, Lawrence D ^a   Coats, Scott A ^a   Ramachandran, Ravi K ^a   Seifert, Ronald A ^a   Schwartz, Stephen M ^a   Bowen Pope, Daniel F ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; FAS ANTIGEN; INTERLEUKIN 1; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1;

ANIMAL CELL; APOPTOSIS; ARTICLE; CAROTID ARTERY; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; MACROPHAGE MIGRATION; MYOSITIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, CD95; APOPTOSIS; CAROTID ARTERIES; CARRIER PROTEINS; CASPASES; CHEMOKINE CCL2; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; INTERLEUKIN-1; INTERLEUKIN-8; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, INBRED F344; UP-REGULATION;

ANIMALIA;

EID: 0033929291     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/77521     Document Type: Article

References (42)

1. Geng, Y.J. & Libby, P. Evidence for apoptosis in advanced human atheroma. Am. J. Pathol. 147, 251-266 (1995).
2. Han, D.K. et al. Evidence for apoptosis in human atherogenesis and in a rat vascular injury model. Am. J. Pothol. 147, 267-277 (1995).
3. Perlman, H., Maillard, L., Krasinski, K. & Walsh, K. Evidence for the rapid onset of apoptosis in medial smooth muscle cells after balloon injury. Circulation 95, 981-987 (1997).
4. Kollum, M. et al. Apoptosis after stent implantation compared with balloon angioplasty in rabbits. Role of macrophages. Arterioscler. Thromb. Vasc. Biol. 17, 2383-2388 (1997).
5. Geng, Y.J., Henderson, L.E., Levesque, E.B., Muszynski, M. & Libby, P. Fas is expressed in human atherosclerotic intima and promotes apoptosis of cytokine-primed human vascular smooth muscle cells. Arterioscler. Thromb. Vase. Biol. 17, 2200-2228 (1997).
6. Kockx, M.M. et al. Apoptosis and related proteins in different stages of human atherosclerotic plaques. Circulation 97, 2307-2315 (1998).
7. Hopkinson-Woolley, J., Hughes, D., Gordon, S. & Martin, P. Macrophage recruitment during limb development and wound healing in the embryonic and foetal mouse. J. Cell Sci 107, 1159-1167 (1994).
8. Savill, J., Fadok, V., Henson, P. & Haslett, C. Phagocyte recognition of cells undergoing apoptosis. Immunol. Today 14, 131-136 (1993).
9. Devitt, A. et al. Human CD14 mediates recognition and phagocytosis of apoptotic cells. Nature 392, 505-509 (1998).
10. Biancone, L. et al. Development of inflammatory angiogenesis by local stimulation of Fas in vivo. J. Inf. Med. 186, 147-152 (1997).
11. Allison, J., Georgiou, H.M., Strasser, A. & Vaux, D.L. Transgenic expression of CD95 ligand on islet beta cells induces a granulocytic infiltration but does not confer immune privilege upon islet a/lografts. Proc. Natl. Acad. Sci. USA 94, 3943-3947 (1997).
12. Seine, K., Kayagaki, N., Okumura, K. & Yagita, H. Antitumor effect of locally produced CD95 ligand. Nature Med. 3, 165-170 (1997).
13. Miwa, K. et al. Caspase 1-independent IL-1 beta release and inflammation induced by the apoptosis inducer Fas ligand. Nature Med. 4, 1287-1292 (1998).
14. Chinnaiyan, A.M., O'Rouke, K., Tewari, M. & Dixit, V.M. FADD, a new death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 81, 505-512 (1995).
15. Clowes, M.M et al. Long-term biological response of injured rat carotid artery seeded with smooth muscle cells expressing retrovirally introduced human genes. J. Clin. Invest. 93, 644-651 (1994).
16. Zagorski, J. & DeLarco, J.E. Rat CINC (cytokine-induced neutrophil chemoat-tractant) is the homolog of the human GRO proteins but is encoded by a single gene. Biochem. Biophys. Res. Commun. 190, 104-110 (1993).
17. Belvisi, M.G. et al. Induction of cyclo-oxygenase-2 by cytokines in human cultured airway smooth muscle cells: new inflammatory role of this cell type. Br. J. Pharmacol. 120, 910-916 (1997).
18. Huang, D.C. et al. Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L). Proc. Natl. Acad. Sci. USA 96, 14871-14876 (1999).
19. Wu, J.C. & Fritz, L.C. Irreversible caspase inhibitors: tools for studying apoptosis. Methods 17, 320-328 (1999).
20. Wang, J.M. et al. Expression of monocyte chemotactic protein and interleukin-8 by cytokine-activated human vascular smooth muscle cells. Arterioscler. Thromb. 11, 1166-1174 (1991).
21. Arend, W.P. Interleukin-1 receptor antagonist. Adv. Immunol. 54, 167-227 (1993).
22. Ross, R. Atherosclerosis - an inflammatory disease. N. Engl. J. Med. 340, 115-126 (1999).
23. Verheyen, A.K., Vlaminckx, E.M., Lauwers, F.M., Saint-Guillain, M.L. & Borgers, M.J. Identification of macrophages in intimai thickening of rat carotid arteries by cytochemical localization of purine nucleoside phosphorylase. Arteriosclerosis 8, 759-767 (1988).
24. Wisniewski, H.G. et al. TNF/IL-1-inducible protein TSG-6 potentiates plasmin inhibition by inter-alpha-inhibitor and exerts a strong anti-inflammatory effect in vivo. J. Immunol. 156, 1609-1615 (1996).
25. Saas, P. et al. CD95 (Fas/Apo-1) as a receptor governing astrocyte apoptotic or inflammatory responses: a key role in brain inflammation? J. Immunol. 162, 2326-2333 (1999).
26. Abreu-Martin, M.T., Vidrich, A., Lynch, D.H. & Targan, S.R. Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNF-alpha and ligation of Fas antigen. J. Immunol. 155, 4147-4154 (1995).
27. Sekine, C. et al. Fas-mediated stimulation induces IL-8 secretion by rheumatoid arthritis synoviocytes independently of CPP32-mediated apoptosis. Biochem. Biophys. Res. Commun. 228, 14-20 (1996).
28. Zhang, J., Cado, D., Chen, A., Kabra, N.H. & Winoto, A. Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature 392, 296-300 (1998).
29. Yeh, W.C. et al. FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 279, 1954-1958(1998).
30. Newton, K., Harris, A.W., Bath, M.L., Smith, K.G.C. & Strasser, A. A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes. EMBO J. 17, 706-718 (1998).
31. Sayers, T.J. et al. Effect of cytokines on polymorphonuclear neutrophil infiltration in the mouse. Prostaglandin-and leukotriene-independent induction of infiltration by IL-1 and tumor necrosis factor. J. Immunol. 141, 1670-1677 (1988).
32. Nelken, N.A., Coughlin, S.R., Gordon, D. & Wilcox, J.N. Monocyte chemoattractant protein-1 in human atheromatous plaques. J. Clin. Invest. 88, 1121-1127 (1991).
33. Reckless, J., Rubin, E.M., Verstuyft, J.B., Metcalfe, J.C. & Grainger, D.J. Monocyte chemoattractant protein-1 but not tumor necrosis factor-alpha is correlated with monocyte infiltration in mouse lipid lesions. Circulation 99, 2310-2316 (1999).
34. Koch, A.E. et al. Enhanced production of the chemotactic cytokines interleukin-8 and monocyte chemoattractant protein-1 in human abdominal aortic aneurysms. Am. J. Pathol. 142, 1423-1431 (1993).
35. Gerszten, R.E. et al. MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Nature 398, 718-723 (1999).
36. Boring, L, Gosling, J., Cleary, M. & Charo, I.F. Decreased lesion formation in CCR2-/-mice reveals a role for chemokines in the initiation of atherosclerosis. Nature 394, 894-897 (1998).
37. Gu, L. et al. Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice. Mol Cell 2, 275-281 (1998).
38. Boisvert, W.A., Santiago, R., Curtiss, L.K. & Terkeltaub, R.A. A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice. J. Clin. Invest. 101, 353-363 (1998).
39. Shockett, P. et al. A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice. Proc. Natl. Acad. Sci. USA 92, 6522-6526 (1995).
40. Kiener, P.A. et al. Differential induction of apoptosis by Fas-Fas ligand interactions in human monocytes and macrophages. J. Exp. Med. 185, 1511-1516 (1997).
41. Lie, Y.S. & Petropoulos, C.J. Advances in quantitative PCR technology: 5¢ nuclease assays. Curr Opin Biotechnol 9, 43-48 (1998).
42. Frevert, C.W., Wong, V.A., Goodman, R.B., Goodwin, R. & Martin, T.R. Rapid fluorescence-based measurement of neutrophil migration in vitro. J. Immunol. Methods 213, 41-52 (1998).