CD95-induced apoptosis of lymphocytes in an immune privileged site induces immunological tolerance

Immunity

Volumn 5, Issue 1, 1996, Pages 7-16

  Griffith, Thomas S ^a   Yu, Xinhong ^a   Herndon, John M ^a   Green, Douglas R ^b   Ferguson, Thomas A ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTERIOR EYE CHAMBER; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENUCLEATION; HERPES SIMPLEX VIRUS 1; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE;

EID: 0030201014     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80305-2     Document Type: Article

References (39)

1. Abbas, A.K. (1996). Die and let live: eliminating dangerous lymphocytes. Cell 84, 655-657.
2. Bellgrau, D., Gold, D., Selawry, H., Moore, J., Franzusoff, A., and Duke, R.C. (1995). A role for CD95 ligand in preventing graft rejection. Nature 377, 630-632.
3. L. Immunity 3, 87-98.
4. L and Bcl-2 repress a common pathway of cell death. J. Exp. Med. 182, 821-828.
5. Ferguson, T., Waldrep, J.C., and Kaplan, H.J. (1987). The immune response and the eye. II. The nature of T suppressor cell induction in anterior chamber associated immune deviation (ACAID). J. Immunol. 139, 352-357.
6. Ferguson, T.A., Hayashi, J., and Kaplan, H.J. (1989). The immune response and the eye. III. Anterior chamber associated immune deviation can be adoptively transferred by serum. J. Immunol. 143, 821-826.
7. Ferguson, T.A., Herndon, J.M., and Dube, P. (1994). The immune response and the eye. IV. A role for tumor necrosis factor in anterior chamber associated immune deviation. Invest. Ophthal. Vis. Sci. 35, 2643-2651.
8. Ferguson, T.A., Fletcher, S., Herndon, J.M., and Griffith, T.S.. (1995). Neuropeptides modulate immune deviation induced via the anterior chamber of the eye. J. Immunol. 155, 1746-1756.
9. Gavriele, Y., Sherman, Y., and Ben-Sasson, S.A. (1992). Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119, 493-501.
10. Griffith, T.S., Brunner, T., Fletcher, S.M., Green, D.R., and Ferguson, T.A. (1995a). Fas ligand-induced apoptosis as a mechanism of immune privilege. Science 270, 1189-1192.
11. Griffith, T.S., Herndon, J.M., Lima, J., Kahn, M., and Ferguson, T.A. (1995b). The immune response and the eye: T cell receptor α-chain related molecules regulate the systemic immunity to antigen presented via the anterior chamber of the eye. Int. Immunol. 7, 1617-1625.
12. Hooper, P., Bora, N., Kaplan, H.J., and Ferguson, T.A. (1991). Inhibition of lymphocyte proliferation by resident ocular cells. Curr. Eye Res. 10, 363-372.
13. + helper T cells and prolonged survival of the corresponding class II H-2-disparate skin graft. J. Immunol. 143, 1447-1452.
14. Iwai, K., Miyawaki, T., Takizawa, T., Konno, A., Ohta, K., Yachie, A., Seki, H., and Taniguchi, N. (1994). Differential expression of Bcl-2 and susceptibility to anti-Fas-mediated cell death in peripheral blood lymphocytes, monocytes, and neutrophils. Blood 4, 1201-1208.
15. Johnston, J.A., Taub, D.D., Lloyd, A., Conlon, K., Oppenheim, J.J., and Kevlin, D.J. (1994). Human T lymphocyte chemotaxis and adhesion induced by vasoactive intestinal peptide. J. Immunol. 153, 1762-1768.
16. Kaplan, H.J., and Streilein, J.W. (1977). Immune response to immunization via the anterior chamber of the eye: I. F1-lymphocyte induced immune deviation. J. Immunol. 118, 809-814.
17. + cells in the murine iris. Invest. Ophthal. Vis. Sci. 32, 2423-2431.
18. Medawar, P.B. (1948). Immunity to homologous grafted skin. III. The fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye. Br. J. Exp. Pathol. 29, 58-69.
19. Mogil, R.J., Radvanyi, L., Gonzalez-Quintial, R., Miller, R., Mills, G., Theofilopoulos, A.N., and Green, D.R. (1995). Fas (CD95) participates in peripheral T cell deletion and associated apoptosis in vivo. Int. Immunol. 7, 1451-1458.
20. Nagata, S. and Suda, T. (1995). Fas and Fas ligand: lpr and gld mutations. Immunol. Today 16, 39-43.
21. Ramsdell, F., Seaman, M.S., Miller, R.E., Picha, K.S., Kennedy, M.K., and Lynch, D.H. (1994). Differential ability of Th1 and Th2 T cells to undergo activation-induced cells death. Int. Immunol. 6, 1545-1553.
22. 2+-independent T cell-mediated cytotoxicity. J. Exp. Med. 177, 195-200.
23. + type 2 cells. J. Exp. Med. 181, 5-7.
24. Singer, G.G., and Abbas, A.K. (1994). The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1, 365-371.
25. Sonoda, Y., and Streilein, J.W. (1993). Impaired cell mediated immunity (ACAID) in mice bearing healthy orthotopic corneal allografts. J. Immunol. 150, 1727-1734.
26. Streilein, J.W., and Niederkorn, J.Y. (1981). Induction of anterior chamber associated immune deviation requires an intact, functional spleen. J. Exp. Med. 153, 1058-1067.
27. Streilein, J.W., Atherton, S.S., and Vann, V. (1987). A critical role for ACAID in the distinctive pattern of retinitis that follows anterior chamber inoculation of HSV-1. Curr. Eye Res. 6, 127-131
28. Takahashi, T., Tanaka, M., Brannan, C.I., Jenkins, N.A., Copeland, N.G., Suda, T., and Nagata, S. (1994). Generalized lymphoproliferative disease in mice caused by a point mutation in the Fas ligand. Cell 76, 969-976.
29. Taylor, A., Streilein, J.W., and Cousins, S.W. (1994). Immunoreactive VIP contributes to immunosuppressive activity of normal aqueous humor. J Immunol. 153, 1080-1086.
30. Thompson, C.B. (1995). Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation? Cell 81, 979-982.
31. Van Dooremaal, J.C. (1873). Die entwickelung der in fremden grund versetzten lebenden gewebe. Albrecht von Graefe's Arch. Ophthalmol. 19, 359-373.
32. Watanabe-Fukunaga, R., Brannan, C.I., Copeland, N.G., Jenkins, N.A., and Nagata, S. (1992). Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356, 314-317.
33. Wetzig, R.P., Foster, S., and Greene, M.I. (1982). Ocular immune responses. I. Priming of A/J mice in the anterior with azobenzenearsonate-derivatized cells induces second-order-like suppressor T cells. J. Immunol. 128, 1753-1759.
34. Whittum-Hudson, J., Farazdaghi, M., and Prendergast, R.A. (1985). A role for T lymphocytes in preventing experimental herpes simplex type 1 retinitis. Invest. Ophthal. Vis. Sci. 26, 1524-1532.
35. Wilbanks, G.A., and Streilein, J.W. (1989). The differing patterns of antigen release and local retention following anterior chamber and intravenous inoculation of soluble antigen: evidence that the eye acts as an antigen depot. Reg. Immunol. 2, 390-397.
36. Wilbanks, G., and Streilein, J.W. (1990). Characterization of suppressor cells in anterior chamber-associated immune deviation (ACAID) induced by soluble antigen: evidence of two functionally and phenotypically distinct T-suppressor cell populations. Immunology 71, 383-389.
37. Wilbanks, G., and Streilein, J.W. (1992). Fluids from immune privileged sites endow macrophages with the capacity to induce antigen-specific immune deviation via a mechanism involving transforming growth factor-β. Eur. J. Immunol. 22, 165-174.
38. Wilbanks, G., Mammolenti, M., and Streilein, J.W. (1991). Studies on the induction of anterior chamber-associated immune deviation (ACAID) II. Eye-derived cells participate in generating blood-borne signals that induce ACAID. J. Immunol. 146, 3018-3024.
39. Wilbanks, G., Mammolenti, M., and Streilein, J.W. (1992). Studies on the induction of anterior chamber-associated immune deviation (ACAID) III. Induction of ACAID depends upon intraocular transforming growth factor-beta. Eur. J. Immunol. 22, 1031-1036.