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Volumn 190, Issue 5, 1999, Pages 639-649

Autoantigen-specific B cell activation in Fas-deficient rheumatoid factor immunoglobulin transgenic mice

Author keywords

Autoantibody; Autoimmunity; B cell tolerance; IgG; Systemic lupus

Indexed keywords

AUTOANTIBODY; FAS ANTIGEN; IMMUNOGLOBULIN; RHEUMATOID FACTOR;

EID: 0032841840     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.190.5.639     Document Type: Article
Times cited : (66)

References (90)
  • 1
    • 0024518559 scopus 로고
    • Antinuclear antibodies: Diagnostic markers for autoimmune diseases and probes for cell biology
    • Tan, E.M. 1989. Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology. Adv. Immunol. 44:93-151.
    • (1989) Adv. Immunol. , vol.44 , pp. 93-151
    • Tan, E.M.1
  • 2
    • 0023277281 scopus 로고
    • Murine monoclonal anti-DNA antibodies bind directly to glomerular antigens and form immune deposits
    • Madaio, M.P., J. Carlson, J. Cataldo, A. Ucci, P. Migliorini, and O. Pankewycz. 1987. Murine monoclonal anti-DNA antibodies bind directly to glomerular antigens and form immune deposits. J. Immunol. 138:2883-2889.
    • (1987) J. Immunol. , vol.138 , pp. 2883-2889
    • Madaio, M.P.1    Carlson, J.2    Cataldo, J.3    Ucci, A.4    Migliorini, P.5    Pankewycz, O.6
  • 3
    • 0024506642 scopus 로고
    • Anti-DNA antibodies bind directly to renal antigens and induce kidney dysfunction in the isolated perfused rat kidney
    • Raz, E., M. Brezis, E. Rosenmann, and D. Eilat. 1989. Anti-DNA antibodies bind directly to renal antigens and induce kidney dysfunction in the isolated perfused rat kidney. J. Immunol. 142:3076-3082.
    • (1989) J. Immunol. , vol.142 , pp. 3076-3082
    • Raz, E.1    Brezis, M.2    Rosenmann, E.3    Eilat, D.4
  • 4
    • 0029899083 scopus 로고    scopus 로고
    • Nephritogenic autoantibodies in lupus
    • Lefkowith, J.B., and G.S. Gilkeson. 1996. Nephritogenic autoantibodies in lupus. Arthritis Rheum. 39:894-903.
    • (1996) Arthritis Rheum. , vol.39 , pp. 894-903
    • Lefkowith, J.B.1    Gilkeson, G.S.2
  • 5
    • 0031882091 scopus 로고    scopus 로고
    • A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice
    • Chan, O., and M.J. Shlomchik. 1998. A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice. J. Immunol. 160:51-59.
    • (1998) J. Immunol. , vol.160 , pp. 51-59
    • Chan, O.1    Shlomchik, M.J.2
  • 6
    • 0026094303 scopus 로고
    • B lymphocytes from the autoimmune-prone mouse strain MRL/lpr manifest an intrinsic defect in tetraparental MRL/lpr DBA/2 chimeras
    • Nemazee, D., C. Guiet, K. Buerki, and A. Marshak-Rothstein. 1991. B lymphocytes from the autoimmune-prone mouse strain MRL/lpr manifest an intrinsic defect in tetraparental MRL/lpr DBA/2 chimeras. J. Immunol. 147:2536-2539.
    • (1991) J. Immunol. , vol.147 , pp. 2536-2539
    • Nemazee, D.1    Guiet, C.2    Buerki, K.3    Marshak-Rothstein, A.4
  • 7
    • 0025729604 scopus 로고
    • An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunity
    • Sobel, E.S., T. Katagiri, K. Katagiri, S.C. Morris, P.L. Cohen, and R.A. Eisenberg. 1991. An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunity. J. Exp. Med. 173: 1441-1449.
    • (1991) J. Exp. Med. , vol.173 , pp. 1441-1449
    • Sobel, E.S.1    Katagiri, T.2    Katagiri, K.3    Morris, S.C.4    Cohen, P.L.5    Eisenberg, R.A.6
  • 9
    • 0022569763 scopus 로고
    • Proliferation of anti-DNA-producing NZB B cells in a non-autoimmune environment
    • Klinman, D.M., and A.D. Steinberg. 1986. Proliferation of anti-DNA-producing NZB B cells in a non-autoimmune environment. J. Immunol. 137:69-75.
    • (1986) J. Immunol. , vol.137 , pp. 69-75
    • Klinman, D.M.1    Steinberg, A.D.2
  • 10
    • 0020565382 scopus 로고
    • Genetic analysis of the inheritance of B cell hyperactivity in relation to the development of autoantibodies and glomerulonephritis in NZB × SWR crosses
    • Eastcott, J.W., R.S. Schwartz, and S.K. Datta. 1983. Genetic analysis of the inheritance of B cell hyperactivity in relation to the development of autoantibodies and glomerulonephritis in NZB × SWR crosses. J. Immunol. 131:2232-2239.
    • (1983) J. Immunol. , vol.131 , pp. 2232-2239
    • Eastcott, J.W.1    Schwartz, R.S.2    Datta, S.K.3
  • 12
    • 0023462643 scopus 로고
    • Structure and function of anti-DNA antibodies derived from a single autoimmune mouse
    • Shlomchik, M.J., A.H. Aucoin, D.S. Pisetsky, and M.G. Weigert. 1987. Structure and function of anti-DNA antibodies derived from a single autoimmune mouse. Proc. Natl. Acad. Sci. USA. 84:9150-9154.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 9150-9154
    • Shlomchik, M.J.1    Aucoin, A.H.2    Pisetsky, D.S.3    Weigert, M.G.4
  • 14
    • 0024349277 scopus 로고
    • IgG anti-DNA antoantibodies within an individual autoimmune mouse are the products of clonal selection
    • Marion, T.N., A.L.M. Bothwell, D.E. Briles, and C.A. Janeway, Jr. 1989. IgG anti-DNA antoantibodies within an individual autoimmune mouse are the products of clonal selection. J. Immunol. 142:4269-4274.
    • (1989) J. Immunol. , vol.142 , pp. 4269-4274
    • Marion, T.N.1    Bothwell, A.L.M.2    Briles, D.E.3    Janeway C.A., Jr.4
  • 16
    • 0026564699 scopus 로고
    • Monoclonal autoantibodies to subnucleosomes from a MRL/Mp(-) +/+ mouse: Oligoclonality of the antibody response and recognition of a determinant composed for histories H2A, H2B, and DNA
    • Losman, M.J., T.M. Fasy, K.E. Novick, and M. Monestier. 1992. Monoclonal autoantibodies to subnucleosomes from a MRL/Mp(-) +/+ mouse: oligoclonality of the antibody response and recognition of a determinant composed for histories H2A, H2B, and DNA. J. Immunol. 148:1561-1569.
    • (1992) J. Immunol. , vol.148 , pp. 1561-1569
    • Losman, M.J.1    Fasy, T.M.2    Novick, K.E.3    Monestier, M.4
  • 18
    • 0025978752 scopus 로고
    • Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus
    • van Es, J.H., F.H. Gmelig-Meylmg, W.R. van De Akker, H. Aanstoot, R.H. Derksen, and T. Logtenberg. 1991. Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus. J. Exp. Med. 173:461-470.
    • (1991) J. Exp. Med. , vol.173 , pp. 461-470
    • Van Es, J.H.1    Gmelig-Meylmg, F.H.2    Van De Akker, W.R.3    Aanstoot, H.4    Derksen, R.H.5    Logtenberg, T.6
  • 19
    • 0026740330 scopus 로고
    • Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas
    • Winkler, T.H., H. Fehr, and J.R. Kalden. 1992. Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas. Eur. J. Immunol. 22:1719-1728.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 1719-1728
    • Winkler, T.H.1    Fehr, H.2    Kalden, J.R.3
  • 20
    • 0031764112 scopus 로고    scopus 로고
    • Strong intrinsic biases towards mutation and conservation of bases in human IgVh genes during somatic hypermutation prevent statistical analysis of antigen selection
    • Dunn-Walters, D.K., and J. Spencer. 1998. Strong intrinsic biases towards mutation and conservation of bases in human IgVh genes during somatic hypermutation prevent statistical analysis of antigen selection. Immunology. 95:339-345.
    • (1998) Immunology , vol.95 , pp. 339-345
    • Dunn-Walters, D.K.1    Spencer, J.2
  • 21
    • 0024529870 scopus 로고
    • Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class-I antibody genes
    • Nemazee, D.A., and K. Burki. 1989. Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class-I antibody genes. Nature. 337:562-566.
    • (1989) Nature , vol.337 , pp. 562-566
    • Nemazee, D.A.1    Burki, K.2
  • 22
    • 0025948793 scopus 로고
    • Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens
    • Hartley, S.B., J. Crosbie, R.A. Brink, A.B. Kantor, A. Basten, and C.C. Goodnow. 1991. Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens. Nature. 353:765-769.
    • (1991) Nature , vol.353 , pp. 765-769
    • Hartley, S.B.1    Crosbie, J.2    Brink, R.A.3    Kantor, A.B.4    Basten, A.5    Goodnow, C.C.6
  • 23
    • 0027478391 scopus 로고
    • Receptor editing in self-reactive bone marrow B cells
    • Tiegs, S.L., D.M. Russell, and D. Nemazee. 1993. Receptor editing in self-reactive bone marrow B cells. J. Exp. Med. 177:1009-1020.
    • (1993) J. Exp. Med. , vol.177 , pp. 1009-1020
    • Tiegs, S.L.1    Russell, D.M.2    Nemazee, D.3
  • 24
    • 0027447188 scopus 로고
    • Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death
    • Hartley, S.B., M.P. Cooke, D.A. Fulcher, A.W. Harris, S. Cory, A. Basten, and C.C. Goodnow. 1993. Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death. Cell. 72:325-335.
    • (1993) Cell , vol.72 , pp. 325-335
    • Hartley, S.B.1    Cooke, M.P.2    Fulcher, D.A.3    Harris, A.W.4    Cory, S.5    Basten, A.6    Goodnow, C.C.7
  • 25
    • 0028129894 scopus 로고
    • Effects of the lpr mutation on elimination and inactivation of self-reactive B cells
    • Rathmell, J.C., and C.C. Goodnow. 1994. Effects of the lpr mutation on elimination and inactivation of self-reactive B cells. J. Immunol. 153:2831-2842.
    • (1994) J. Immunol. , vol.153 , pp. 2831-2842
    • Rathmell, J.C.1    Goodnow, C.C.2
  • 26
    • 0029994303 scopus 로고    scopus 로고
    • Analysis of central B cell tolerance in autoimmune-prone MRL/lpr mice bearing autoantibody transgenes
    • Rubio, C.F., J. Kench, D.M. Russell, R. Yawger, and D. Nemazee. 1996. Analysis of central B cell tolerance in autoimmune-prone MRL/lpr mice bearing autoantibody transgenes. J. Immunol. 157:65-71.
    • (1996) J. Immunol. , vol.157 , pp. 65-71
    • Rubio, C.F.1    Kench, J.2    Russell, D.M.3    Yawger, R.4    Nemazee, D.5
  • 27
    • 0025980973 scopus 로고
    • Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice
    • Erikson, J., M.Z. Radic, S.A. Camper, R.R. Hardy, and M.G. Weigert. 1991. Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice. Nature. 349:331-334.
    • (1991) Nature , vol.349 , pp. 331-334
    • Erikson, J.1    Radic, M.Z.2    Camper, S.A.3    Hardy, R.R.4    Weigert, M.G.5
  • 28
    • 0027499537 scopus 로고
    • Receptor editing: An approach by autoreactive B cells to escape tolerance
    • Gay, D., T. Saunders, S. Camper, and M. Weigert. 1993. Receptor editing: an approach by autoreactive B cells to escape tolerance. J. Exp. Med. 177:999-1008.
    • (1993) J. Exp. Med. , vol.177 , pp. 999-1008
    • Gay, D.1    Saunders, T.2    Camper, S.3    Weigert, M.4
  • 30
    • 0032487526 scopus 로고    scopus 로고
    • Regulation of anti-DNA B cells in recombination-activating gene-deficient mice
    • Xu, H., H. Li, E. Suri-Payer, R.R. Hardy, and M. Weigert. 1998. Regulation of anti-DNA B cells in recombination-activating gene-deficient mice. J. Exp. Med. 188:1247-1254.
    • (1998) J. Exp. Med. , vol.188 , pp. 1247-1254
    • Xu, H.1    Li, H.2    Suri-Payer, E.3    Hardy, R.R.4    Weigert, M.5
  • 31
    • 0029071783 scopus 로고
    • B cell selection and allelic exclusion of an anti-DNA Ig transgene in MRL-lpr/lpr mice
    • Roark, J.H., C.L. Kuntz, K.A. Nguyen, L. Mandik, M. Cattermole, and J. Erikson. 1995. B cell selection and allelic exclusion of an anti-DNA Ig transgene in MRL-lpr/lpr mice. J. Immunol. 154:4444-4455.
    • (1995) J. Immunol. , vol.154 , pp. 4444-4455
    • Roark, J.H.1    Kuntz, C.L.2    Nguyen, K.A.3    Mandik, L.4    Cattermole, M.5    Erikson, J.6
  • 32
    • 0030827382 scopus 로고    scopus 로고
    • Regulation of anti-double-stranded DNA B cells in nonautoimmune mice: Localization to the T-B interface of the splenic follicle
    • Mandik-Nayak, L., A. Bui, H. Noorchashm, A. Eaton, and J. Erikson. 1997. Regulation of anti-double-stranded DNA B cells in nonautoimmune mice: localization to the T-B interface of the splenic follicle. J. Exp. Med. 186:1257-1267.
    • (1997) J. Exp. Med. , vol.186 , pp. 1257-1267
    • Mandik-Nayak, L.1    Bui, A.2    Noorchashm, H.3    Eaton, A.4    Erikson, J.5
  • 34
    • 0030734276 scopus 로고    scopus 로고
    • Persistence of functionally compromised antidouble-stranded DNA B cells in the periphery of non-autoimmune mice
    • Roark, J.H., A. Bui, K.-A.T. Nguyen, L. Mandik, and J. Erikson. 1997. Persistence of functionally compromised antidouble-stranded DNA B cells in the periphery of non-autoimmune mice. Int. Immunol. 9:1615-1629.
    • (1997) Int. Immunol. , vol.9 , pp. 1615-1629
    • Roark, J.H.1    Bui, A.2    Nguyen, K.-A.T.3    Mandik, L.4    Erikson, J.5
  • 36
    • 0027985599 scopus 로고
    • Lack of allelic exclusion permits autoreactive B cells to escape deletion
    • Iliev, A., L. Spatz, S. Ray, and B. Diamond. 1994. Lack of allelic exclusion permits autoreactive B cells to escape deletion. J. Immunol. 153:3551-3556.
    • (1994) J. Immunol. , vol.153 , pp. 3551-3556
    • Iliev, A.1    Spatz, L.2    Ray, S.3    Diamond, B.4
  • 38
    • 0032212186 scopus 로고    scopus 로고
    • B cell deletion, anergy, and receptor editing in "knock in" mice targeted with a germline-encoded or somatically mutated anti-DNA heavy chain
    • Pewzner-Jung, Y., D. Friedmann, E. Sonoda, S. Jung, K. Rajewsky, and D. Eilat. 1998. B cell deletion, anergy, and receptor editing in "knock in" mice targeted with a germline-encoded or somatically mutated anti-DNA heavy chain. J. Immunol. 161:4634-4645.
    • (1998) J. Immunol. , vol.161 , pp. 4634-4645
    • Pewzner-Jung, Y.1    Friedmann, D.2    Sonoda, E.3    Jung, S.4    Rajewsky, K.5    Eilat, D.6
  • 39
    • 0028931042 scopus 로고
    • Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus
    • Roark, J.H., C.L. Kuntz, K.A. Nguyen, A.J. Caton, and J. Erikson. 1995. Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus. J. Exp. Med. 181: 1157-1167.
    • (1995) J. Exp. Med. , vol.181 , pp. 1157-1167
    • Roark, J.H.1    Kuntz, C.L.2    Nguyen, K.A.3    Caton, A.J.4    Erikson, J.5
  • 41
    • 0029854905 scopus 로고    scopus 로고
    • A disease-related RF autoantibody is not tolerized in a normal mouse: Implications for the origins of autoantibodies in autoimmune disease
    • Hannum, L.G., D. Ni, A.M. Haberman, M.G. Weigert, and M.J. Shlomchik. 1996. A disease-related RF autoantibody is not tolerized in a normal mouse: implications for the origins of autoantibodies in autoimmune disease. J. Exp. Med. 184: 1269-1278.
    • (1996) J. Exp. Med. , vol.184 , pp. 1269-1278
    • Hannum, L.G.1    Ni, D.2    Haberman, A.M.3    Weigert, M.G.4    Shlomchik, M.J.5
  • 43
    • 0021173447 scopus 로고
    • Induction of various autoantibodies by mutant gene lpr in several strains of mice
    • Izui, S., V.E. Kelley, K. Masuda, H. Yoshida, J.B. Roths, and E.D. Murphy. 1984. Induction of various autoantibodies by mutant gene lpr in several strains of mice. J. Immunol. 133: 227-233.
    • (1984) J. Immunol. , vol.133 , pp. 227-233
    • Izui, S.1    Kelley, V.E.2    Masuda, K.3    Yoshida, H.4    Roths, J.B.5    Murphy, E.D.6
  • 44
  • 46
    • 0031205293 scopus 로고    scopus 로고
    • High affinity rheumatoid factor transgenic B cells are eliminated in normal mice
    • Wang, H., and M.J. Shlomchik. 1997. High affinity rheumatoid factor transgenic B cells are eliminated in normal mice. J. Immunol. 159:1125-1134.
    • (1997) J. Immunol. , vol.159 , pp. 1125-1134
    • Wang, H.1    Shlomchik, M.J.2
  • 47
    • 0025245009 scopus 로고
    • IL-5 induces a Pgp-1 (CD44) bright B cell subpopulation that is highly enriched in proliferative and Ig secretory activity and binds to hyaluronate
    • Murakami, S., K. Miyake, C.H. June, P.W. Kincade, and R.J. Hodes. 1990. IL-5 induces a Pgp-1 (CD44) bright B cell subpopulation that is highly enriched in proliferative and Ig secretory activity and binds to hyaluronate. J. Immunol. 145: 3618-3627.
    • (1990) J. Immunol. , vol.145 , pp. 3618-3627
    • Murakami, S.1    Miyake, K.2    June, C.H.3    Kincade, P.W.4    Hodes, R.J.5
  • 48
    • 0026093449 scopus 로고
    • High levels of CD44 expression distinguish virgin from antigen-primed B cells
    • Camp, R.L., T.A. Kraus, M.L. Birkeland, and E. Pure. 1991. High levels of CD44 expression distinguish virgin from antigen-primed B cells. J. Exp. Med. 173:763-766.
    • (1991) J. Exp. Med. , vol.173 , pp. 763-766
    • Camp, R.L.1    Kraus, T.A.2    Birkeland, M.L.3    Pure, E.4
  • 49
    • 0025951891 scopus 로고
    • Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens
    • Liu, Y.J., J. Zhang, P.J. Lane, E.Y. Chan, and I.C. MacLennan. 1991. Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens. Eur. J. Immunol. 21:2951-2962.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2951-2962
    • Liu, Y.J.1    Zhang, J.2    Lane, P.J.3    Chan, E.Y.4    MacLennan, I.C.5
  • 50
    • 0023878494 scopus 로고
    • Successive changes of the cellular composition in lymphoid organs of MRL-Mp/lpr/lpr mice during the development of lymphoproliferative disease as investigated in cryosections
    • Lieberum, B., and K.U. Hartmann. 1988. Successive changes of the cellular composition in lymphoid organs of MRL-Mp/lpr/lpr mice during the development of lymphoproliferative disease as investigated in cryosections. Clin. Immunol. Immunopathol. 46:421-431.
    • (1988) Clin. Immunol. Immunopathol. , vol.46 , pp. 421-431
    • Lieberum, B.1    Hartmann, K.U.2
  • 51
    • 0028789148 scopus 로고
    • Anatomy of autoantibody production: Dominant localization of antibody-producing cells to T cell zones in Fas-deficient mice
    • Jacobson, B.A., D.J. Panka, K.A. Nguyen, J. Erikson, A.K. Abbas, and A. Marshak-Rothstein. 1995. Anatomy of autoantibody production: dominant localization of antibody-producing cells to T cell zones in Fas-deficient mice. Immunity. 3:509-519.
    • (1995) Immunity. , vol.3 , pp. 509-519
    • Jacobson, B.A.1    Panka, D.J.2    Nguyen, K.A.3    Erikson, J.4    Abbas, A.K.5    Marshak-Rothstein, A.6
  • 53
    • 0022599651 scopus 로고
    • Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice
    • Davidson, W.F., F.J. Dumont, H.G. Bedigian, B.J. Fowlkes, and H.C.I. Morse. 1986. Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice. J. Immunol. 136:4075-4084.
    • (1986) J. Immunol. , vol.136 , pp. 4075-4084
    • Davidson, W.F.1    Dumont, F.J.2    Bedigian, H.G.3    Fowlkes, B.J.4    Morse, H.C.I.5
  • 55
    • 0024425654 scopus 로고
    • + B lymphocytes, polyreactive antibodies and the human B-cell repertoire
    • + B lymphocytes, polyreactive antibodies and the human B-cell repertoire. Immunol. Today. 10:364-368.
    • (1989) Immunol. Today , vol.10 , pp. 364-368
    • Casali, P.1    Notkins, A.L.2
  • 57
    • 0025876601 scopus 로고
    • Comparison of natural antibodies to autoantibodies arising during lupus in (NZB × NZW)F1 mice
    • Hentati, B., T. Ternynck, S. Avrameas, and B. Payelle-Brogard. 1991. Comparison of natural antibodies to autoantibodies arising during lupus in (NZB × NZW)F1 mice. J. Autoimmun. 4:341-356.
    • (1991) J. Autoimmun. , vol.4 , pp. 341-356
    • Hentati, B.1    Ternynck, T.2    Avrameas, S.3    Payelle-Brogard, B.4
  • 58
    • 0023204355 scopus 로고
    • Systemic autoimmune disease arises from polyclonal B cell activation
    • Klinman, D.M., and A.D. Steinberg. 1987. Systemic autoimmune disease arises from polyclonal B cell activation. J. Exp. Med. 165:1755-1760.
    • (1987) J. Exp. Med. , vol.165 , pp. 1755-1760
    • Klinman, D.M.1    Steinberg, A.D.2
  • 59
    • 0025136806 scopus 로고
    • Development of the autoimmune B cell repertoire in MRL-lpr/lpr mice
    • Klinman, D.M., R.A. Eisenberg, and A.D. Steinberg. 1990. Development of the autoimmune B cell repertoire in MRL-lpr/lpr mice. J. Immunol. 144:506-511.
    • (1990) J. Immunol. , vol.144 , pp. 506-511
    • Klinman, D.M.1    Eisenberg, R.A.2    Steinberg, A.D.3
  • 60
    • 0026501593 scopus 로고
    • Similarities in B cell repertoire development between autoimmune and aging normal mice
    • Klinman, D. 1992. Similarities in B cell repertoire development between autoimmune and aging normal mice. J. Immunol. 148:1353-1358.
    • (1992) J. Immunol. , vol.148 , pp. 1353-1358
    • Klinman, D.1
  • 62
    • 0030753789 scopus 로고    scopus 로고
    • Induction of autoimmunity. A role for the idiotypic network
    • Shoenfeld, Y., and J. George. 1997. Induction of autoimmunity. A role for the idiotypic network. Ann. NY Acad. Sci. 815:342-349.
    • (1997) Ann. NY Acad. Sci. , vol.815 , pp. 342-349
    • Shoenfeld, Y.1    George, J.2
  • 64
    • 0027073188 scopus 로고
    • Expression of surface lymphotoxin and tumor necrosis factor on activated T, B, and natural killer cells
    • Ware, C.F., P.D. Crowe, M.H. Grayson, M.J. Androlewicz, and J.L. Browning. 1992. Expression of surface lymphotoxin and tumor necrosis factor on activated T, B, and natural killer cells. J. Immunol. 149:3881-3888.
    • (1992) J. Immunol. , vol.149 , pp. 3881-3888
    • Ware, C.F.1    Crowe, P.D.2    Grayson, M.H.3    Androlewicz, M.J.4    Browning, J.L.5
  • 65
    • 0030913257 scopus 로고    scopus 로고
    • - B cells: Possible involvement in age-associated cytokine dysregulation
    • - B cells: possible involvement in age-associated cytokine dysregulation. Int. Immunol. 9:745-754.
    • (1997) Int. Immunol. , vol.9 , pp. 745-754
    • Spencer, N.F.L.1    Daynes, R.A.2
  • 66
    • 0032489920 scopus 로고    scopus 로고
    • B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin α-dependent fashion
    • Fu, Y.X., G. Huang, Y. Wang, and D.D. Chaplin. 1998. B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin α-dependent fashion. J. Exp. Med. 187:1009-1018.
    • (1998) J. Exp. Med. , vol.187 , pp. 1009-1018
    • Fu, Y.X.1    Huang, G.2    Wang, Y.3    Chaplin, D.D.4
  • 69
    • 0033577903 scopus 로고    scopus 로고
    • A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus
    • Chan, O.T., L.G. Hannum, A.M. Haberman, M.P. Madaio, and M.J. Shlomchik. 1999. A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus. J. Exp. Med. 189:1639-1648.
    • (1999) J. Exp. Med. , vol.189 , pp. 1639-1648
    • Chan, O.T.1    Hannum, L.G.2    Haberman, A.M.3    Madaio, M.P.4    Shlomchik, M.J.5
  • 70
    • 0026031973 scopus 로고
    • Efficient and selective presentation of antigen-antibody complexes by rheumatoid factor B cells
    • Roosnek, E., and A. Lanzavecchia. 1991. Efficient and selective presentation of antigen-antibody complexes by rheumatoid factor B cells J. Exp. Med. 173:487-489.
    • (1991) J. Exp. Med. , vol.173 , pp. 487-489
    • Roosnek, E.1    Lanzavecchia, A.2
  • 71
    • 0028898599 scopus 로고
    • Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I
    • Maldonado, M.A., R.A. Eisenberg, E. Roper, P.L. Cohen, and B.L. Kotzin. 1995. Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I. J. Exp. Med. 181:641-648.
    • (1995) J. Exp. Med. , vol.181 , pp. 641-648
    • Maldonado, M.A.1    Eisenberg, R.A.2    Roper, E.3    Cohen, P.L.4    Kotzin, B.L.5
  • 72
    • 0028985378 scopus 로고
    • + T cells but normal autoantibody production in Ipr/lpr mice lacking major histocompatibility complex class I molecules
    • + T cells but normal autoantibody production in Ipr/lpr mice lacking major histocompatibility complex class I molecules. Eur. J. Immunol. 25:37-41.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 37-41
    • Ohteki, T.1    Iwamoto, M.2    Izui, S.3    Macdonald, H.R.4
  • 73
    • 0028238410 scopus 로고
    • Activation induces sensitivity toward APO-1 (CD95)-mediated apoptosis in human B cells
    • Daniel, P.T., and P.M. Krammer. 1994. Activation induces sensitivity toward APO-1 (CD95)-mediated apoptosis in human B cells. J. Immunol. 152:5624-5632.
    • (1994) J. Immunol. , vol.152 , pp. 5624-5632
    • Daniel, P.T.1    Krammer, P.M.2
  • 74
    • 0028799882 scopus 로고
    • Expression and function of the murine CD95/FasR/APO-1 receptor in relation to B cell ontogeny
    • Onel, K.B., C.L. Tucek-Szabo, D. Ashany, E. Lacy, J. Nikolic-Zugic, and K.B. Elkon. 1995. Expression and function of the murine CD95/FasR/APO-1 receptor in relation to B cell ontogeny. Eur. J. Immunol. 25:2940-2947.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 2940-2947
    • Onel, K.B.1    Tucek-Szabo, C.L.2    Ashany, D.3    Lacy, E.4    Nikolic-Zugic, J.5    Elkon, K.B.6
  • 75
    • 0028840913 scopus 로고
    • Fas receptor expression on B-lineage cells
    • Mandik, L., K.-A. Nguyen, and J. Erikson. 1995. Fas receptor expression on B-lineage cells. Eur. J. Immunol. 25:3148-3154.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 3148-3154
    • Mandik, L.1    Nguyen, K.-A.2    Erikson, J.3
  • 76
    • 0029416937 scopus 로고
    • Expression of Fas in B cells of the mouse germinal center and Fas-dependent killing of activated B cells
    • Watanabe, D., T. Suda, and S. Nagata. 1995. Expression of Fas in B cells of the mouse germinal center and Fas-dependent killing of activated B cells. Int. Immunol. 7:1949-1956.
    • (1995) Int. Immunol. , vol.7 , pp. 1949-1956
    • Watanabe, D.1    Suda, T.2    Nagata, S.3
  • 78
    • 0030071885 scopus 로고    scopus 로고
    • The Fas antigen is detected on immature B cells and the representative cell lines show Fas-mediated apoptosis
    • Nishiuchi, R., T. Yoshino, Y. Matsuo, I. Sakuma, L. Cao, Y. Seino, K. Takahashi, and T. Akagi. 1996. The Fas antigen is detected on immature B cells and the representative cell lines show Fas-mediated apoptosis. Br. J. Haematol. 92:302-307.
    • (1996) Br. J. Haematol. , vol.92 , pp. 302-307
    • Nishiuchi, R.1    Yoshino, T.2    Matsuo, Y.3    Sakuma, I.4    Cao, L.5    Seino, Y.6    Takahashi, K.7    Akagi, T.8
  • 79
    • 0032532290 scopus 로고    scopus 로고
    • Fas/APO-1 (CD95)-mediated apoptosis is activated by interferon-γ and interferon-α in interleukin-6 (IL-6)-dependent and IL-6-independent multiple myeloma cell lines
    • Spets, H., P. Georgii-Hemming, J. Silajason, K. Nilsson, and H. Jernberg-Wiklund. 1998. Fas/APO-1 (CD95)-mediated apoptosis is activated by interferon-γ and interferon-α in interleukin-6 (IL-6)-dependent and IL-6-independent multiple myeloma cell lines. Blood. 92:2914-2923.
    • (1998) Blood , vol.92 , pp. 2914-2923
    • Spets, H.1    Georgii-Hemming, P.2    Silajason, J.3    Nilsson, K.4    Jernberg-Wiklund, H.5
  • 80
    • 0029589915 scopus 로고
    • Fas is highly expressed in the germinal center but is not required for regulation of the B-cell response to antigen
    • Smith, K.G., G.J. Nossal, and D.M. Tarlinton. 1995. Fas is highly expressed in the germinal center but is not required for regulation of the B-cell response to antigen. Proc. Natl. Acad. Sci. USA. 92:11628-11632.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11628-11632
    • Smith, K.G.1    Nossal, G.J.2    Tarlinton, D.M.3
  • 81
    • 0028785538 scopus 로고
    • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-tolerance
    • Han, S., B. Zheng, J. Dal Porto, and G. Kelsoe. 1995. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. IV. Affinity-dependent, antigen-driven B cell apoptosis in germinal centers as a mechanism for maintaining self-tolerance. J. Exp. Med. 182:1635-1644.
    • (1995) J. Exp. Med. , vol.182 , pp. 1635-1644
    • Han, S.1    Zheng, B.2    Dal Porto, J.3    Kelsoe, G.4
  • 82
    • 0030584786 scopus 로고    scopus 로고
    • Greatly accelerated lymphadenopathy and autoimmune disease in lpr mice lacking tumor necrosis factor receptor 1
    • Zhou, T., C.K.I. Edwards, P. Yang, Z. Wang, H. Bluethmann, and J.D. Mountz. 1996. Greatly accelerated lymphadenopathy and autoimmune disease in lpr mice lacking tumor necrosis factor receptor 1. J. Immunol. 156:2661-2665.
    • (1996) J. Immunol. , vol.156 , pp. 2661-2665
    • Zhou, T.1    Edwards, C.K.I.2    Yang, P.3    Wang, Z.4    Bluethmann, H.5    Mountz, J.D.6
  • 83
    • 0028036918 scopus 로고
    • Autoimmune disease-a problem of defective apoptosis
    • Mountz, J.D., J. Wu, J. Cheng, and T. Zhou. 1994. Autoimmune disease-a problem of defective apoptosis. Arthritis Rheum. 37:1415-1420.
    • (1994) Arthritis Rheum. , vol.37 , pp. 1415-1420
    • Mountz, J.D.1    Wu, J.2    Cheng, J.3    Zhou, T.4
  • 84
    • 0031568575 scopus 로고    scopus 로고
    • Susceptibility loci for lupus: A guiding light from murine models?
    • Kotzin, B.L. 1997. Susceptibility loci for lupus: a guiding light from murine models? J. Clin. Invest. 99:557-558.
    • (1997) J. Clin. Invest. , vol.99 , pp. 557-558
    • Kotzin, B.L.1
  • 90
    • 0032822989 scopus 로고    scopus 로고
    • Somatic mutation and light chain rearrangement generate autoimmunity in anti-single-stranded DNA transgenic MRL/lpr mice
    • Brard, F., M. Shannon, E.L. Prak, S. Litwin, and M. Weigert. 1999. Somatic mutation and light chain rearrangement generate autoimmunity in anti-single-stranded DNA transgenic MRL/lpr mice. J. Exp. Med. 190:691-704.
    • (1999) J. Exp. Med. , vol.190 , pp. 691-704
    • Brard, F.1    Shannon, M.2    Prak, E.L.3    Litwin, S.4    Weigert, M.5


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