Non-cleavable mutant fas ligand transfection of donor cornea abrogates ocular immune privilege

Experimental Eye Research

Volumn 75, Issue 4, 2002, Pages 475-483

  Sano, Yoichiro ^a   Yamada, Jun ^a   Ishino, Yutaka ^a   Adachi, Wakako ^a   Kawasaki, Satoshi ^a   Suzuki, Tomo ^a   Kinoshita, Shigeru ^a   Okuyama, Torayuki ^b   Azuma, Noriyuki ^b  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

Author keywords

ACAID; Corneal transplantation; Gene transfer; Immune privilege; Immunoregulation; Inflammation

Indexed keywords

ADENOVIRUS VECTOR; COMPLEMENTARY DNA; CRE RECOMBINASE; FAS ANTIGEN; FAS LIGAND; MUTANT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CORNEA OPACITY; CORNEA TRANSPLANTATION; DONOR; DRUG BINDING; DRUG EFFECT; GENETIC TRANSFECTION; GRAFT SURVIVAL; HISTOLOGY; IMMUNOREGULATION; MEMBRANE BINDING; MOUSE; NONHUMAN; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; SLIT LAMP;

EID: 0036035697     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4835(02)92044-0     Document Type: Article

References (36)

1. Allison, J., Georgiou, H. M., Strasser, A. and Vaux, D. L. (1997). Transgenic expression of CD95 ligand on islet beta cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts. Proc. Nat. Acad. Sci. U.S.A. 94, 3943-7.
2. Bellgrau, D., Gold, D., Selawry, H., Moore, J., Franzusoff, A. and Duke, R. C. (1995). A role for CD95 ligand in preventing graft rejection. Nature 377, 630-2.
3. Chen, J. J., Sun, Y. and Nabel, G. J. (1998). Regulation of the proinflammatory effects of Fas ligand (CD95L). Science 282, 1714-7.
4. Dana, M. R., Zhu, S. N. and Yamada, J. (1998). Topical modulation of interluekin-1 activity in corneal neovascularization. Cornea 17, 403-9.
5. Griffith, T. S., Brunner, T., Fletcher, S. M., Green, D. R. and Ferguson, T. A. (1995). Fas ligand-induced apoptosis as a mechanism of immune privilege. Science 270, 1189-92.
6. Hahne, M., Rimoldi, D., Schroter, M., Romero, P., Schreier, M., French, L. E., Schneider, P., Bornand, T., Fontana, A., Lienard, D., Cerottini, J. and Tschopp, J. (1996). Melanoma cell expression of Fas (APO-1/CD95) ligand - Implications for tumor immune escape. Science 274, 1363-6.
7. Hohlbaum, B. A., Moe, S. and Marshak-Rothstein, A. (2000). Opposing effects of transmembrane and soluble Fas ligand expression on inflammation and tumor cell survival. J. Exp. Med. 191, 1209-19.
8. Kang, S. M., Schneider, D. B., Lin, Z., Hanahan, D., Dichek, D. A., Stock, P. G. and Baeldceskov, S. (1997). Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction. Nat. Med. 3, 738-43.
9. Kang, S. M., Braat, D., Schneider, D. B., O'Rourke, R. W., Lin, Z., Ascher, N. L., Dichek, D. A., Baeldceskov, S. and Stock, P. G. (2000). A non-cleavable mutant of Fas ligand does not prevent neutrophilic destruction of islet transplants. Transplantation 69, 1813-7.
10. Li, X. K., Okuyama, T., Tamura, A., Enosawa, S., Kaneda, Y., Takahara, S., Funashima, N., Yamada, M., Amemiya, H. and Suzuki, S. (1998). Prolonged survival of rat liver allografts transfected with Fas ligand-expressing plasmid. Transplantation 66, 1416-23.
11. Miwa, K., Asano, M., Horai, R., Iwakura, Y., Nagata, S. and Suda, T. (1998). Caspase 1-independent IL-lb release and inflammation induced by the apoptosis inducer of Fas ligand. Nat. Med. 4, 1287-92.
12. Miyake, S., Makimura, M., Kanegae, Y., Harada, S., Sato, Y., Takamori, K., Tokuda, C. and Saito, I. (1996). Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc. Nat. Acad. Sci. U.S.A. 93, 1320-4.
13. Nagata, S. and Suda, T. (1995). Fas and Fas ligand: lpr and gld mutations. Immunol. Today 16, 39-43.
14. Niederkorn, J. Y. (1999). The immunology of corneal transplantation. Dev. Ophthalmol. 30, 129-40.
15. Okuyama, T., Fujino, M., Li, X. K., Funeshima, N., Kosuga, M., Saito, I., Suzuki, S. and Yamada, M. (1998). Efficient Fas-ligand gene expression in rodent liver after intravenous injection of a recombinant adenovirus by the use of a Cre-mediated switching system. Gene Ther. 5, 1047-53.
16. Ottonello, L., Tortolina, G., Amelotti, M. and Dallegri, F. (1999). Soluble Fas ligand is chemotactic for human neutrophilic polymorphonuclear leukocytes. J. Immunol. 162, 3601-6.
17. Sambrook, J. E., Fritsch, F. and Maniatis, T. (1989). Construction and analysis of cDNA library. In Molecular Cloning: A Laboratory Manual, 2nd Ed. Cold Spring Harbor Laboratory: Cold Spring Harbor, NY, U.S.A., p8.1.
18. Sano, Y., Ksander, B. R. and Streilein, J. W. (1995). Fate of orthotopic corneal allografts in eyes that cannot support anterior chamber-associated immune deviation induction. Invest. Ophthalmol. Vis. Sci. 36, 2176-85.
19. Smith, R. E., McDonald, H. R., Newburn, A. D. and Minckler, D. S. (1980). Penetrating keratoplasty: Changing indications, 1947 to 1978. Arch. Ophthalmol. 98, 1226-9.
20. Sonoda, Y. and Streilein, J. W. (1992). Orthotopic corneal transplantation in mice: Evidence that the immunogenetic rules of rejection do not apply. Transplantation 54, 694-704.
21. Strand, S. W., Hofmann, J., Hug, H., Muller, M., Otto, G., Strand, D., Mariani, S. M., Stremmel, W., Krammer, P. H. and Galle, P. R. (1996). Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells - A mechanism of immune evasion? Nat. Med. 2, 1361-6.
22. Strasser, A. and O'Connor, L. (1998). Fas ligand - Caught between Scylla and Charybdis. Nat. Med. 4, 21-2.
23. Streilein, J. W. (1987). Immune regulation and the eye: A dangerous compromise. FASEB J. 1, 199-208.
24. Streilein, J. W. and Bradley, D. (1991). Analysis of immunosuppressive properties of iris and ciliary body cells and their secretory products. Invest. Ophthalmol. Vis. Sci. 32, 2700-10.
25. Streilein, J. W., Wilbanks, G. A., Taylor, A. and Cousins, S. (1992). Eye-derived cytokines and the immunosuppressive intraocular microenvironment: A review. Curt. Eye. Res. ll(Suppl.): 41-7.
26. Streilein, J. W., Bradley, D., Sano, Y. and Sonoda, Y. (1996). Immunosuppressive properties of tissues obtained from eyes with experimentally manipulated corneas. Invest. Ophthalmol. Vis. Sci. 37, 413-24.
27. Stuart, P. M., Griffith, T. S., Usui, N., Pepose, J., Yu, X. and Ferguson, T. A. (1997). CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival. J. Clin. Invest. 99, 396-402.
28. Suda, T., Takahashi, T., Golstein, P. and Nagata, S. (1993). Molecular cloning and expression of the Fas ligand: a novel member of the tumor necrosis factor family. Cell 75, 1169-78.
29. Suda, T. and Nagata, S. (1997). Why do defects in the Fas-Fas ligand system cause autoimmunity? J. Allerg. Clin. Immunol. 100, S97-S101.
30. Swenson, K. M., Ke, B., Wang, T., Markowitz, J. S., Maggard, M. A., Spear, G. S., Imagawa, D. K., Goss, J. A., Busuttil, R. W. and Seu, P. (1998). Fas ligand gene transfer to renal allografts in rats. Transplantation 65, 155-60.
31. Takeuchi, T., Ueki, T., Nishimatsu, H., Kajiwara, T., Ishida, T., Jishage, K., Ueda, O., Suzuki, H., Li, B., Moriyama, N. and Kitamura, T. (1999). Accelerated rejection of Fas ligand-expressing heart grafts. J. Immunol. 162, 518-22.
32. Tanaka, M., Suda, T., Haze, K., Nakamura, N., Sato, K., Kimura, F., Motoyoshi, K., Mizuki, M., Tagawa, S., Ohga, S., Hatake, K., Drummond, A. H. and Nagata, S. (1996). Fas ligand in human serum. Nat. Med. 2, 317-22.
33. Walker, P. R., Saas, P. and Dietrich, P. Y. (1998). Tumor expression of Fas ligand (CD95L) and the consequences. Curr. Opin. Immunol. 10, 564-72.
34. Yagita, H., Seino, K., Kayagaki, N. and Okumura, K. (1996). CD95 ligand in graft rejection [letter]. Nature 379, 682.
35. Yamada, J., Zhu, S. N., Streilein, J. W. and Dana, M. R. (2000). Interleukin-1 receptor antagonist therapy and induction of anterior chamber-associated immune deviation-type tolerance after corneal transplantation. Invest. Ophthalmol. Vis. Sci. 41, 4203-8.
36. Yamagami, S., Kawashima, H., Tsuru, T., Yamagami, H., Kayagaki, N., Yagita, H., Okumura, K. and Gregerson, D. S. (1997). Role of Fas-Fas ligand interactions in the immunorejection of allogeneic mouse corneal transplants. Transplantation 64, 1107-11.