Dendritic cells transduced with viral interleukin 10 or Fas ligand: No evidence for induction of allotolerance in vivo

Transplantation

Volumn 73, Issue 1 SUPPL., 2002, Pages

  Buonocore, Sofia ^a   Van Meirvenne, Sonja ^a   Demoor, François Xavier ^a   Paulart, Frédéric ^a   Thielemans, Kris ^a   Goldman, Michel ^a   Flamand, Véronique ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; FAS LIGAND; INTERLEUKIN 10; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; BONE MARROW CELL; CELL DEATH; CONFERENCE PAPER; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DENDRITIC CELL; DNA MODIFICATION; GENE TRANSFER; GENETIC TRANSDUCTION; GRAFT REJECTION; IMMUNOREGULATION; IMMUNOSUPPRESSIVE TREATMENT; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; MIXED LYMPHOCYTE CULTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROVIRUS; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TRANSPLANTATION TOLERANCE; VIRUS RECOMBINANT;

EID: 0037080564     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200201151-00010     Document Type: Conference Paper

References (20)

1. -) prolong cardiac allograft survival in non-immunosuppressed recipients
2. Immature dendritic cells generated with low doses of GM-CSF in the absence of IL-4 are maturation resistant and prolong allograft survival in vivo
3. + T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
4. Retrovirus-mediated transfer of viral IL-10 gene prolongs murine cardiac allograft survival
5. T cell stimulation upon long-term secretion of viral IL-10
6. A role for CD95 ligand in preventing graft rejection
7. Fas ligand-induced apoptosis as a mechanism of immune privilege
8. A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis
9. Fas ligand (CD95L) and B7 expression on dendritic cells provide counter-regulatory signals for T cell survival and proliferation
10. The Fas counterattack: Cancer as a site of immune privilege
11. Induction of the IL-10 gene via the Fas receptor in monocytes: An anti-inflammatory mechanism in the absence of apoptosis
12. Prevention of islet allograft rejection with engineered myoblasts expressing FasL in mice
13. Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction
14. Transgenic expression of CD95 ligand on islet β cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts
15. Accelerated rejection of Fas ligand-expressing heart grafts
16. Induction of antigen-specific immunosuppression by CD95L cDNA-transfected killer dendritic cells
17. Dendritic cells genetically engineered to express Fas ligand induce donor-specific hypo-responsiveness and prolong allograft survival
18. Regulation of the pro-inflammatory effects of Fas ligand (CD95L)
19. + T cell responses to Fas engagement
20. The induction of tolerance by dendritic cells that have captured apoptotic cells