Defective Fas Ligand-Mediated Apoptosis Predisposes to Development of a Chronic Erosive Arthritis Subsequent to Mycoplasma pulmonis Infection

Arthritis and Rheumatism

Volumn 44, Issue 9, 2001, Pages 2146-2159

  Hsu, Hui Chen ^a   Zhang, Huang Ge ^a   Song, Gwan Gyu ^b   Xie, Jingping ^c   Liu, Di ^a   Yang, PingAr ^a   Fleck, Martin ^d   Wintersberger, Winfried ^e   Zhou, Tong ^a   Edwards III, Carl K ^f   Mountz, John D ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b Korea University College of Medicine   (South Korea)

^c UNIVERSITY OF MICHIGAN   (United States)

^d UNIVERSITY OF REGENSBURG   (Germany)

^e UNIVERSITY OF VIENNA   (Austria)

^f AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS LIGAND; FASL PROTEIN, MOUSE; MEMBRANE PROTEIN;

ACUTE DISEASE; ADENOVIRUS; ANIMAL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; BACTERIAL INFECTION; CHRONIC DISEASE; CYTOLOGY; DISEASE MODEL; GENE THERAPY; GENETICS; IMMUNOLOGY; LYMPH NODE; MALE; MICROBIOLOGY; MOUSE; MOUSE MUTANT; PATHOLOGY; REACTIVE ARTHRITIS; SYNOVIUM; T LYMPHOCYTE;

ACUTE DISEASE; ADENOVIRIDAE; ANIMALS; APOPTOSIS; ARTHRITIS, REACTIVE; B-LYMPHOCYTES; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; FAS LIGAND PROTEIN; GENE THERAPY; LYMPH NODES; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, MUTANT STRAINS; MYCOPLASMA INFECTIONS; SYNOVIAL MEMBRANE; T-LYMPHOCYTES;

EID: 18044400416     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(200109)44:9<2146::AID-ART368>3.0.CO;2-O     Document Type: Article

References (45)

1. Leirisalo-Repo M, Helenius P, Hannu T, Lehtinen A, Kreula J, Taavitsaincn M, et al. Long-term prognosis of reactive salmonella arthritis. Ann Rheum Dis 1997;56:516-20.
2. Yli-Kerttula T, Tertti R, Toivancn A. Ten-year follow up study of patients from a Yersinia pseudotuberculosis III outbreak. Clin Exp Rheumatol 1995;13:333-7.
3. Burmester GR, Daser A, Kamradt T, Krause A, Mitchison NA, Sieper J, et al. Immunology of reactive arthritides. Annu Rev Immunol 1995;13:229-50.
4. Marker-Hermann E, Hohler T. Pathogenesis of human leukocyte antigen B27-positive arthritis: information from clinical materials. Rheum Dis Clin North Am 1998;24:865-81.
5. Schumacher HR Jr, Gérard HC, Arayssi TK, Pando JA, Branigan PJ, Saaibi DL, et al. Lower prevalence of Chlamydia pneumoniae DNA compared with Chlamydia trachomatis DNA in synovial tissue of arthritis patients. Arthritis Rheum 1999;42:1889-93.
6. Gerard HC, Schumacher HR, El-Gabalawy H, Goldbach-Mansky R, Hudson AP. Chlamydia pneumoniae present in the human synovium are viable and metabolically active. Microb Pathog 2000;29:17-24.
7. Urvater JA, McAdam SN, Lochrke JH, Allen TM, Moran JL, Rowell TJ, et al. A high incidence of Shigella-induced arthritis in a primate species: major histocompatibility complex class I molecules associated with resistance and susceptibility, and their relationship to HLA-B27. Immunogenetics 2000;51:314-25.
8. Lee S, Khare SD, Griffiths MM, Luthra HS, David CS. HLA-B27 transgenic mice are susceptible to collagen-induced arthritis: type II collagen as a potential target in human disease. Hum Immunol 2000;61:140-7.
9. Ikeda M, Yu DT. The pathogenesis of HLA-B27 arthritis: role of HLA-B27 in bacterial defense. Am J Med Sci 1998;316:257-63.
10. Berman A, Cahn P, Perez H, Spindler A, Lucero E, Paz S, et al. Human immunodeficiency virus infection associated arthritis: clinical characteristics. J Rheumatol 1999;26:1158-62.
11. Fleck M, Kern ER, Zhou T, Podlech J, Wintersberger W, Edwards CK III, et al. Apoptosis mediated by Fas but not tumor necrosis factor receptor 1 prevents chronic disease in mice infected with marine cytomegalovirus. J Clin Invest 1998;102:1431-43.
12. Zhang HG, Fleck M, Kern ER, Liu D, Wang YM, Hsu H-C, et al. Administration of Fas ligand expressing antigen-presenting cells down modulates MCMV-induced chronic inflammatory disease in Fas ligand deficient mice. J Clin Invest 2000;105:813-21.
13. Horowitz S, Evinson B, Borer A, Horowitz J. Mycoplasma fermentans in rheumatoid arthritis and other inflammatory arthritides. J Rheumatol 2000;27:2747-53.
14. Haier J, Nasralla M, Franco AR, Nicolson GL. Detection of mycoplasmal infections in blood of patients with rheumatoid arthritis. Rheumatology (Oxford) 1999;38:504-9.
15. Johnson S, Sidebottom D, Bruckner F, Collins D. Identification of Mycoplasma fermentans in synovial fluid samples from arthritis patients with inflammatory disease. J Clin Microbiol 2000;38:90-3.
16. Henry CH, Hughes CV, Gerard HC, Hudson AP, Wolford LM. Reactive arthritis: preliminary microbiologic analysis of the human temporomandibular joint. J Oral Maxillofac Surg 2000;58: 1137-42; discussion 1143-4.
17. Keystone EC, Taylor-Robinson D, Osborn MF, Ling L, Pope C, Fornasier V. Effect of T-cell deficiency on the chronicity of arthritis induced in mice by Mycoplasma pulmonis. Infect Immun 1980;27:192-6.
18. Schutze E, Laber G, Walzl H. Clinical and histopathological findings in mycoplasmal polyarthritis of rats. III. Course of infection during the weeks 7-30 and 54-61. Zentralbl Bakteriol [Orig A] 1976;234:91-104.
19. Hagedorn-Olsen T, Nielsen NC, Friis NF. Induction of arthritis with Mycoplasma hyosynoviae in pigs: clinical response and reisolation of the organism from body fluids and organs. Zentralbl Veterinarmed A 1999;46:317-25.
20. Keystone EC, Taylor-Robinson D, Metcalfe A, Ling L, Fornasier V, Pope C. Role of viable mycoplasmas in the pathogenesis of arthritis induced by M. pulmonis. Br J Exp Pathol 1981;62:350-6.
21. Kono M, Yoshioka M, Imai M, Hirose S. Mycoplasma pulmonis arthritis in mice: microbiological and immunological features. Microbiol Immunol 1985;29:645-57.
22. Lai WC, Bennett M, Pakes SP, Kumar V, Steutermann D, Owusu I, et al. Resistance to Mycoplasma pulmonis mediated by activated natural killer cells. J Infect Dis 1990;161:1269-75.
23. Evengard B, Sandstedt K, Bolske G, Feinstein R, Riesenfelt-Orn I, Smith CI. Intranasal inoculation of Mycoplasma pulmonis in mice with severe combined immunodeficiency (SCID) causes a wasting disease with grave arthritis. Clin Exp Immunol 1994;98: 388-94.
24. Zhang HG, Liu D, Heike Y, Yang P, Wang Z, Wang X, et al. Induction of specific T-cell tolerance by adenovirus-transfected, Fas ligand-producing antigen presenting cells. Nat Biotechnol 1998;16:1045-9.
25. Faulkner CB, Simecka JW, Davidson MK, Davis JK, Schoeb TR, Lindsey JR, et al. Gene expression and production of tumor necrosis factor alpha, interleukin 1, interleukin 6, and gamma interferon in C3H/HeN and C57BL/6N mice in acute Mycoplasma pulmonis disease. Infect Immun 1995;63:4084-90.
26. Fleck M, Zhou T, Su X, Li L, Lin S, Lindsey R, et al. Chronic synovitis in Fas deficient C57BL/6 lpr/lpr mice triggered by mycoplasma infection: a new animal model for RA [abstract]. Arthritis Rheum 1996;39 Suppl 9:S115.
27. Edwards CK III, Zhou T, Zhang J, Baker TJ, De M, Long RE, et al. Inhibition of superantigen-induced proinflammatory cytokine production and inflammatory arthritis in MRL-lpr/lpr mice by a transcriptional inhibitor of TNF-alpha. J Immunol 1996;157: 1758-72.
28. Davidson MK, Davis JK, Lindsey JR, Cassell GH. Clearance of different strains of Mycoplasma pulmonis from the respiratory tract of C3H/HeN mice. Infect Immun 1988;56:2163-8.
29. Schoeb TR, Dybvig K, Keisling KF, Davidson MK, Davis JK. Detection of Mycoplasma pulmonis in cilia-associated respiratory bacillus isolates and in respiratory tracts of rats by nested PCR. J Clin Microbiol 1997;35:1667-70.
30. Yao Q, Glorioso JC, Evans CH, Robbins PD, Kovesdi I, Oligino TJ, et al. Adenoviral mediated delivery of FAS ligand to arthritic joints causes extensive apoptosis in the synovial lining. J Gene Med 2000;2:210-9.
31. Okamoto K, Asahara H, Kobayashi T, Matsuno H, Hasunuma T, Kobata T, et al. Induction of apoptosis in the rheumatoid synovium by Fas ligand gene transfer. Gene Ther 1998;5:331-8.
32. Zhang H, Yang Y, Horton JL, Samoilova EB, Judge TA, Turka LA, et al. Amelioration of collagen-induced arthritis by CD95 (Apo-1/Fas)-ligand gene transfer. J Clin Invest 1997;100:1951-7.
33. Hasunuma T, Hoa TT, Aono H, Asahara H, Yonehara S, Yamamoto K, et al. Induction of Fas-dependent apoptosis in synovial infiltrating cells in rheumatoid arthritis. Int Immunol 1996;8:1595-602.
34. Cartner SC, Lindsey JR, Gibbs-Erwin J, Cassell GH, Simecka JW. Roles of innate and adaptive immunity in respiratory mycoplasmosis. Infect Immun 1998;66:3485-91.
35. Okamoto K, Kobayashi T, Kobata T, Hasunuma T, Kato T, Sumida T, et al. Fas-associated death domain protein is a Fasmediated apoptosis modulator in synoviocytes. Rheumatology (Oxford) 2000;39:471-80.
36. Ohshima S, Mima T, Sasai M, Nishioka K, Shimizu M, Murata N, et al. Tumour necrosis factor alpha (TNF-alpha) interferes with Fas-mediated apoptotic cell death on rheumatoid arthritis (RA) synovial cells: a possible mechanism of rheumatoid synovial hyperplasia and a clinical benefit of anti-TNF-alpha therapy for RA. Cytokine 2000;12:281-8.
37. Kobayashi T, Okamoto K, Kobata T, Hasunuma T, Sumida T, Nishioka K. Tumor necrosis factor α regulation of the Fasmediated apoptosis-signaling pathway in synovial cells. Arthritis Rheum 1999;42:519-26.
38. Georgantas RW III, Leong KW, August JT. Antigen-specific induction of peripheral T cell tolerance in vivo by codelivery of DNA vectors encoding antigen and Fas ligand. Hum Gene Ther 2000;11:851-8.
39. Gao Y, Herndon JM, Zhang H, Griffith TS, Ferguson TA. Antiinflammatory effects of CD95 ligand (FasL)-induced apoptosis. J Exp Med 1998;188:887-96.
40. Warnatz K, Kyburz D, Brinson DC, Lee DJ, von Damm A, Engelhart M, et al. Rheumatoid factor B cell tolerance via autonomous Fas/FasL-independent apoptosis. Cell Immunol 1999; 191:69-73.
41. Kono M, Tanaka H, Yayoshi M, Araake M, Yoshioka M, Imai M. Mycoplasma pulmonis arthritis in congenitally athymic (nude) mice: histopathological features. Microbiol Immunol 1980;24: 381-91.
42. Zhao Y-X, Zhang H, Chiu B, Payne U, Inman RD. Tumor necrosis factor receptor p55 controls the severity of arthritis in experimental Yersinia enterocolitica infection. Arthritis Rheum 1999;42:1662-72.
43. Lai WC, Linton G, Bennett M, Pakes SP. Genetic control of resistance to Mycoplasma pulmonis infection in mice. Infect Immun 1993;61:4615-21.
44. Lai WC, Pakes SP, Bennett M. Natural resistance to Mycoplasma pulmonis infection in mice: host resistance gene(s) map to chromosome 4. Nat Immun 1996-97;15:241-8.
45. Fujisawa K, Asahara H, Okamoto K, Aono H, Hasunuma T, Kobata T, et al. Therapeutic effect of the anti-Fas antibody on arthritis in HTLV-1 tax transgenic mice. J Clin Invest 1996;98: 271-8.