Indefinite allograft survival mediated by donor bone marrow is dependent on the presence of a functional CD95 (Fas) gene in recipients

Journal of Heart and Lung Transplantation

Volumn 20, Issue 10, 2001, Pages 1132-1135

  Goldstein, Daniel R ^a   Thomas, Judith M ^b   Kirklin, James K ^c   George, James F ^a,b,c  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c Kentucky   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; THYMOCYTE ANTIBODY;

ANIMAL MODEL; APOPTOSIS; ARTICLE; BONE MARROW; CONTROLLED STUDY; DONOR; GENE; GENE EXPRESSION; GRAFT SURVIVAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECIPIENT; SKIN ALLOGRAFT; SKIN TRANSPLANTATION; SURVIVAL TIME;

ANIMALS; ANTIGENS, CD95; ANTILYMPHOCYTE SERUM; BONE MARROW TRANSPLANTATION; GRAFT SURVIVAL; IMMUNOSUPPRESSIVE AGENTS; LIVING DONORS; MICE; MICE, INBRED C57BL; TRANSPLANTATION, HOMOLOGOUS;

EID: 0034805466     PISSN: 10532498     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1053-2498(01)00302-3     Document Type: Article

References (13)

1. Specific tolerance to canine renal allografts following treatment with fractionated bone marrow and antilymphocyte serum
2. Use of allogenic, homozygous bone marrow cells for the induction of specific immunologic tolerance in mice treated with antilymphocyte serum
3. Renal allograft tolerance induced with ATG and donor bone marrow in outbred rhesus monkeys
4. Further studies of veto activity in rhesus monkey bone marrow in relation to allograft tolerance and chimerism
5. The effect of injection of donor bone marrow on the frequency of donor-reactive CTL in antilymphocyte serum-treated, grafted mice
6. Apoptosis, graft rejection, and transplantation tolerance
7. An essential role for fas-ligand in transplantation tolerance
8. Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance
9. Intrathymic deletion of alloreactive T cells in mixed bone marrow chimeras prepared with a nonmyeloablative conditioning
10. Cellular basis of long-term organ transplant acceptance: Pivotal role of intrathymic clonal deletion and thymic dependence of bone marrow microchimerism-associated tolerance
11. Apoptosis mediated by the TNF-related cytokine and receptor families
12. Pathways leading to cell death in T cells
13. Enhanced allograft survival induced by posttransplant donor spleen cell infusion occurs via a mechanism that is distinct from the mechanism of enhancement by donor bone marrow