-
1
-
-
0037192320
-
Toxicology and genetic toxicology in the new era of 'toxicogenom-ics': Impact of '-omics' technologies
-
Aardema, M. J. and MacGregor, J. T. (2002): Toxicology and genetic toxicology in the new era of 'toxicogenom-ics': impact of '-omics' technologies. Mutat. Res, 499: 13-25.
-
(2002)
Mutat. Res
, vol.499
, pp. 13-25
-
-
Aardema, M.J.1
MacGregor, J.T.2
-
2
-
-
0029874668
-
The sensitivity of the NTP bioassay for carcinogen hazard evaluation can be modulated by dietary restriction
-
Abdo, K. M. and Kari, F. W. (1996): The sensitivity of the NTP bioassay for carcinogen hazard evaluation can be modulated by dietary restriction. Exp. Toxicol. Pathol, 48: 129-137.
-
(1996)
Exp. Toxicol. Pathol
, vol.48
, pp. 129-137
-
-
Abdo, K.M.1
Kari, F.W.2
-
3
-
-
0030460005
-
FDA points-to-consider documents: The need for dietary control for the reduction of experimental variability within animal assays and the use of dietary restriction to achieve dietary control
-
Allaben, W. T., Turturro, A., Leakey, J. E. A., Seng, J. E., and Hart, R. W. (1996): FDA points-to-consider documents: the need for dietary control for the reduction of experimental variability within animal assays and the use of dietary restriction to achieve dietary control. Toxicol. Pathol, 24:776-781.
-
(1996)
Toxicol. Pathol
, vol.24
, pp. 776-781
-
-
Allaben, W.T.1
Turturro, A.2
Leakey, J.E.A.3
Seng, J.E.4
Hart, R.W.5
-
4
-
-
0024306410
-
Influence of hormonal disturbances on transplacental and multigeneration carcinogen-esis in rats
-
edited by N. P. Napalkov, J. M. Rice, L. Tomatis, and H. Yamasaki, IARC Publ. No. 96, Lyon, France
-
Alexandrov, V. A., Popovich, I. G., Anisimov, V. N., and Napalkov, N. P. (1989): Influence of hormonal disturbances on transplacental and multigeneration carcinogen-esis in rats. In: Perinatal and Multigeneration Carcinogenesis, edited by N. P. Napalkov, J. M. Rice, L. Tomatis, and H. Yamasaki, IARC Publ. No. 96, pp. 35-19. Lyon, France.
-
(1989)
Perinatal and Multigeneration Carcinogenesis
, pp. 35-19
-
-
Alexandrov, V.A.1
Popovich, I.G.2
Anisimov, V.N.3
Napalkov, N.P.4
-
6
-
-
0028120357
-
Neoplastic lesions of questionable significance to humans
-
Alison, R. H., Capen, C. C., and Prentice, D. E. (1994): Neoplastic lesions of questionable significance to humans. Toxicol. Pathol., 22:179-186.
-
(1994)
Toxicol. Pathol
, vol.22
, pp. 179-186
-
-
Alison, R.H.1
Capen, C.C.2
Prentice, D.E.3
-
7
-
-
3242884003
-
Prediction of rodent carcinogenesis: An evaluation of prechronic liver lesions as forecasters of liver tumors in NTP carcinogenicity studies
-
Allen, D. G., Pearse, G., Haseman, J. K., and Maronpot, R. R. (2004): Prediction of rodent carcinogenesis: an evaluation of prechronic liver lesions as forecasters of liver tumors in NTP carcinogenicity studies. Toxicol. Pathol., 32:393-401.
-
(2004)
Toxicol. Pathol
, vol.32
, pp. 393-401
-
-
Allen, D.G.1
Pearse, G.2
Haseman, J.K.3
Maronpot, R.R.4
-
8
-
-
33750539822
-
-
American Cancer Society, Atlanta, GA
-
Jemal, A., Siegel, R., Ward, E., Murray, T., Xu, J., and Thun, M., Eds. (2005): Cancer Statistics 2007, pp. 43-66. American Cancer Society, Atlanta, GA.
-
(2005)
Cancer Statistics 2007
, pp. 43-66
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
Thun, M.6
-
9
-
-
0025321016
-
Relevance of maximum tolerated dose to human carcinogenic risk
-
Apostolou, A. (1990): Relevance of maximum tolerated dose to human carcinogenic risk. Regul. Toxicol. Pharmacol., 11:68-80.
-
(1990)
Regul. Toxicol. Pharmacol
, vol.11
, pp. 68-80
-
-
Apostolou, A.1
-
10
-
-
0000973407
-
Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP
-
Ashby, J. and Tennant, R. W. (1991): Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP. Mutat. Res., 257:229-306.
-
(1991)
Mutat. Res
, vol.257
, pp. 229-306
-
-
Ashby, J.1
Tennant, R.W.2
-
11
-
-
15044344653
-
Carcinogenicity evaluation: Comparison of tumor data from dual control groups in the Spra-gue-Dawley rat
-
Baldrick, P. (2005): Carcinogenicity evaluation: comparison of tumor data from dual control groups in the Spra-gue-Dawley rat. Toxicol. Pathol., 33:283-291.
-
(2005)
Toxicol. Pathol
, vol.33
, pp. 283-291
-
-
Baldrick, P.1
-
12
-
-
0014263049
-
Biopharmaceutical consideration in subcutaneous and intramuscular drug administration
-
Ballard, B. E. (1968): Biopharmaceutical consideration in subcutaneous and intramuscular drug administration. J. Pharmacol. Sci., 57:357-378.
-
(1968)
J. Pharmacol. Sci
, vol.57
, pp. 357-378
-
-
Ballard, B.E.1
-
13
-
-
66549100725
-
The breast
-
edited by E. Rubin and J. L. Farber, J.B. Lippincott, Philadelphia, PA
-
Bartow, S. A. (1994): The breast. In: Pathology, edited by E. Rubin and J. L. Farber, pp. 73-992. J.B. Lippincott, Philadelphia, PA.
-
(1994)
Pathology
, pp. 73-992
-
-
Bartow, S.A.1
-
15
-
-
0032449819
-
Dose selection for carcinogenicity studies of pharmaceuticals: Systemic exposure to phenacetin at carcinogenic dosage in the rat
-
Bergman, K., Olofsson, I.-M., and Sjoeberg, P. (1998): Dose selection for carcinogenicity studies of pharmaceuticals: systemic exposure to phenacetin at carcinogenic dosage in the rat. Regul. Toxicol. Pharmacol., 28: 226-229.
-
(1998)
Regul. Toxicol. Pharmacol
, vol.28
, pp. 226-229
-
-
Bergman, K.1
Olofsson, I.-M.2
Sjoeberg, P.3
-
17
-
-
0016723180
-
Some fundamental considerations of the applications of pharmacokinetics to cancer chemotherapy
-
Bischoff, K. B. (1975): Some fundamental considerations of the applications of pharmacokinetics to cancer chemotherapy. Cancer Chemother. Rep., 59:777-793.
-
(1975)
Cancer Chemother. Rep
, vol.59
, pp. 777-793
-
-
Bischoff, K.B.1
-
18
-
-
27744481100
-
Application of the threshold of toxicological concern approach to ingredients in personal and household care products
-
Blackburn, K., Stickney, J. A., Carlson-Lynch, H. L., McGinnis, P. M., Chappell, L., and Felter, S. P. (2005): Application of the threshold of toxicological concern approach to ingredients in personal and household care products. Regul. Toxicol. Pharmacol., 43:249-259.
-
(2005)
Regul. Toxicol. Pharmacol
, vol.43
, pp. 249-259
-
-
Blackburn, K.1
Stickney, J.A.2
Carlson-Lynch, H.L.3
McGinnis, P.M.4
Chappell, L.5
Felter, S.P.6
-
19
-
-
0032878541
-
/- mouse
-
/- mouse. Toxicol. Pathol., 27(5):519-527.
-
(1999)
Toxicol. Pathol
, vol.27
, Issue.5
, pp. 519-527
-
-
Blanchard, K.T.1
Barthel, C.2
French, J.E.3
Holden, H.E.4
Moretz, R.5
Pack, F.D.6
Tennant, R.W.7
Stoll, R.E.8
-
20
-
-
0028308415
-
Frequency of spontaneous tumours in Wistar rats in 2-year studies
-
Bomhard, E. and Rinke, M. (1994): Frequency of spontaneous tumours in Wistar rats in 2-year studies. Exp. Toxicol. Pathol, 46:17-29.
-
(1994)
Exp. Toxicol. Pathol
, vol.46
, pp. 17-29
-
-
Bomhard, E.1
Rinke, M.2
-
21
-
-
0033790789
-
Major inter-species differences in the rates of O-sulphonation and O-glucuronylation of alpha-hydroxytamoxifen in vitro: A metabolic disparity protecting human liver from the formation of tamoxifen-DNA adducts
-
Boocock, D. J., Maggs, J. L., Brown, K., White, I. N., and Park, B. K. (2000): Major inter-species differences in the rates of O-sulphonation and O-glucuronylation of alpha-hydroxytamoxifen in vitro: a metabolic disparity protecting human liver from the formation of tamoxifen-DNA adducts. Carcinogenesis, 21(10):1851-1858.
-
(2000)
Carcinogenesis
, vol.21
, Issue.10
, pp. 1851-1858
-
-
Boocock, D.J.1
Maggs, J.L.2
Brown, K.3
White, I.N.4
Park, B.K.5
-
22
-
-
0000905316
-
Quality assurance in pathology for rodent carcinogenicity studies
-
edited by H. Milman and E. Weisburger. Noyes, Park Ridge, NJ
-
Boorman, G. A., Montgomery, Jr., C. A., Eustis, S. L., Wolfe, M. J. McConnell, E. E., and Hardisty, J. F. (1985): Quality assurance in pathology for rodent carcinogenicity studies. In: Handbook of Carcinogen Testing, edited by H. Milman and E. Weisburger, pp. 345-357, Noyes, Park Ridge, NJ.
-
(1985)
Handbook of Carcinogen Testing
, pp. 345-357
-
-
Boorman, G.A.1
Montgomery, C.A.2
Eustis, S.L.3
Wolfe, M.J.4
McConnell, E.E.5
Hardisty, J.F.6
-
23
-
-
0028022553
-
Rodent carcinogenicity bioassay: Past, present and future
-
Boorman, G. A., Maronpot, R. R., and Eustis, S. L. (1994): Rodent carcinogenicity bioassay: past, present and future. Toxicol. Pathol., 22:105-111.
-
(1994)
Toxicol. Pathol
, vol.22
, pp. 105-111
-
-
Boorman, G.A.1
Maronpot, R.R.2
Eustis, S.L.3
-
24
-
-
0036188952
-
Quality review procedures necessary for rodent pathology databases and toxicoge-nomic studies: The National Toxicology Program experience
-
Boorman, G. A., Haseman, J. K., Waters, M. D., Hardisty, J. F., and Sills, R. C. (2002): Quality review procedures necessary for rodent pathology databases and toxicoge-nomic studies: the National Toxicology Program experience. Toxicol. Pathol. 30(1):88-92.
-
(2002)
Toxicol. Pathol
, vol.30
, Issue.1
, pp. 88-92
-
-
Boorman, G.A.1
Haseman, J.K.2
Waters, M.D.3
Hardisty, J.F.4
Sills, R.C.5
-
25
-
-
0015082651
-
Mechanism of enhanced drug effects produced by dilution of the oral dose
-
Borowitz, J. L., Moore, P. F., Yim, G. K. W., and Miya, T. S. (1971): Mechanism of enhanced drug effects produced by dilution of the oral dose. Toxicol. Appl. Pharmacol., 19:164-168.
-
(1971)
Toxicol. Appl. Pharmacol
, vol.19
, pp. 164-168
-
-
Borowitz, J.L.1
Moore, P.F.2
Yim, G.K.W.3
Miya, T.S.4
-
26
-
-
24044551627
-
The in vivo comet assay: Use and status in genotoxicity testing
-
Brendler-Schwaab, S., Hartmann, A., Pfuhler, S., and Speit, G. (2005): The in vivo comet assay: use and status in genotoxicity testing. Mutagenesis, 20(4):245-254.
-
(2005)
Mutagenesis
, vol.20
, Issue.4
, pp. 245-254
-
-
Brendler-Schwaab, S.1
Hartmann, A.2
Pfuhler, S.3
Speit, G.4
-
27
-
-
22244437298
-
Incidences of selected lesions in control female Harlan Sprague-Dawley rats from two-year studies performed by the National Toxicology Program
-
Brix, A. E., Nyska, A., Haseman, J. K., Sells, D. M., Jokinen, M. P., and Walker, N. J. (2004): Incidences of selected lesions in control female Harlan Sprague-Dawley rats from two-year studies performed by the National Toxicology Program. Toxicol. Pathol., 33:477-183.
-
(2004)
Toxicol. Pathol
, vol.33
, pp. 477-183
-
-
Brix, A.E.1
Nyska, A.2
Haseman, J.K.3
Sells, D.M.4
Jokinen, M.P.5
Walker, N.J.6
-
28
-
-
0036387533
-
In ovo carcinogenicity assay (IOCA): Evaluation of mannitol, caprolactam and nitrosoproline
-
Brunnemann, K. D., Enzmann, H. G., Perrone, C. E., Iatro-poulos, M. J., and Williams, G. M. (2002): In ovo carcinogenicity assay (IOCA): evaluation of mannitol, caprolactam and nitrosoproline. Arch. Toxicol., 76:606-612.
-
(2002)
Arch. Toxicol
, vol.76
, pp. 606-612
-
-
Brunnemann, K.D.1
Enzmann, H.G.2
Perrone, C.E.3
Iatro-poulos, M.J.4
Williams, G.M.5
-
29
-
-
0025681360
-
Efficacy and safety of omeprazole in the long-term treatment of peptic ulcer and reflux oesophagitis resistant to ranitidine
-
Brunner, G. H. G., Lamberts, R., and Creutzfeldt, W. (1990): Efficacy and safety of omeprazole in the long-term treatment of peptic ulcer and reflux oesophagitis resistant to ranitidine. Digestion, 47:64-68.
-
(1990)
Digestion
, vol.47
, pp. 64-68
-
-
Brunner, G.H.G.1
Lamberts, R.2
Creutzfeldt, W.3
-
30
-
-
22544483238
-
Demystification of 21 CRF Part 556: Tolerances for residues of new animal drugs in food
-
Brynes, S. D. (2005): Demystification of 21 CRF Part 556: tolerances for residues of new animal drugs in food. Regulatory Toxicol. Pharmacol., 42:324-327.
-
(2005)
Regulatory Toxicol. Pharmacol
, vol.42
, pp. 324-327
-
-
Brynes, S.D.1
-
31
-
-
0031008968
-
Mesenchymal tumors of the mouse urinary bladder with vascular and smooth muscle differentiation
-
Butler, W. H., Cohen, S. H., and Squire, R. A. (1997): Mesenchymal tumors of the mouse urinary bladder with vascular and smooth muscle differentiation. Toxicol. Pathol, 25:268-274.
-
(1997)
Toxicol. Pathol
, vol.25
, pp. 268-274
-
-
Butler, W.H.1
Cohen, S.H.2
Squire, R.A.3
-
32
-
-
0023619956
-
A protocol and guide for the in vivo rat hepatocyte DNA repair assay
-
Butterworth, B. E., Ashby, J., Bermudez, E., Casciano, D., Mirsalis, J., Probst, G., and Williams, G. (1987): A protocol and guide for the in vivo rat hepatocyte DNA repair assay. Mutat. Res., 189:123-133.
-
(1987)
Mutat. Res
, vol.189
, pp. 123-133
-
-
Butterworth, B.E.1
Ashby, J.2
Bermudez, E.3
Casciano, D.4
Mirsalis, J.5
Probst, G.6
Williams, G.7
-
33
-
-
0026094912
-
The role of cell proliferation in multistage carcinogenesis
-
Butterworth, B. E. and Goldsworthy, T. L. (1991): The role of cell proliferation in multistage carcinogenesis. Proc. Soc. Exp. Biol. Med., 198:683-687.
-
(1991)
Proc. Soc. Exp. Biol. Med
, vol.198
, pp. 683-687
-
-
Butterworth, B.E.1
Goldsworthy, T.L.2
-
35
-
-
0029156692
-
An introduction to drug disposition: The basic principles of absorption, distribution, metabolism and excretion
-
Caldwell, J., Gardner, I., and Swales, N. (1995): An introduction to drug disposition: the basic principles of absorption, distribution, metabolism and excretion. Toxicol. Pathol., 23:148-157.
-
(1995)
Toxicol. Pathol
, vol.23
, pp. 148-157
-
-
Caldwell, J.1
Gardner, I.2
Swales, N.3
-
36
-
-
0029557855
-
Mechanisms of hormone-mediated carcino-genesis of the ovary in mice
-
Capen, C. C., Beamer, W. G., Tennant, B. J., and Stitzel, K. A. (1995): Mechanisms of hormone-mediated carcino-genesis of the ovary in mice. Mutat. Res., 333:143-151.
-
(1995)
Mutat. Res
, vol.333
, pp. 143-151
-
-
Capen, C.C.1
Beamer, W.G.2
Tennant, B.J.3
Stitzel, K.A.4
-
37
-
-
27644519691
-
Gene expression profiling of the PPAR-alpha agonist ciprofibrate in the cynomolgus monkey liver
-
Cariello, N. F., Romach, E. H., Colton, H. M., Ni, H., Yoon, L. et al. (2005): Gene expression profiling of the PPAR-alpha agonist ciprofibrate in the cynomolgus monkey liver. Toxicol. Sci., 88(1):250-264.
-
(2005)
Toxicol. Sci
, vol.88
, Issue.1
, pp. 250-264
-
-
Cariello, N.F.1
Romach, E.H.2
Colton, H.M.3
Ni, H.4
Yoon, L.5
-
38
-
-
0029089711
-
Considerations in the design of tox-icokinetic programs
-
Cayen, M. N. (1995): Considerations in the design of tox-icokinetic programs. Toxicol. Pathol., 23:148-157.
-
(1995)
Toxicol. Pathol
, vol.23
, pp. 148-157
-
-
Cayen, M.N.1
-
39
-
-
5544232698
-
Role of toxicoki-netics in dose selection for carcinogenicity studies
-
edited by P. G. Welling and F. A. de la Iglesia, Marcel Dekker, New York
-
Cayen, M. N. and Black, H. E. (1993): Role of toxicoki-netics in dose selection for carcinogenicity studies. In: Drug Toxicokinetics, edited by P. G. Welling and F. A. de la Iglesia, pp. 69-83. Marcel Dekker, New York.
-
(1993)
Drug Toxicokinetics
, pp. 69-83
-
-
Cayen, M.N.1
Black, H.E.2
-
40
-
-
0025767307
-
Extrapolation of toxicological and pharmacological data from animals to humans
-
Chappell, W. R. and Mordenti, J. (1991): Extrapolation of toxicological and pharmacological data from animals to humans. Adv. Drug Res., 20:2-116.
-
(1991)
Adv. Drug Res
, vol.20
, pp. 2-116
-
-
Chappell, W.R.1
Mordenti, J.2
-
41
-
-
1542606886
-
-
Raven Press, New York
-
Chengelis, C. P., Gad, S. C., and Holston, J. (1995): Regulatory Toxicology, Raven Press, New York.
-
(1995)
Regulatory Toxicology
-
-
Chengelis, C.P.1
Gad, S.C.2
Holston, J.3
-
42
-
-
0031948482
-
Effect of dietary optimization on growth, survival, tumor incidences and clinical pathology parameters in CD Sprague-Dawley and Fischer-344 rats: A 104-week study
-
Christian, M. S., Hoberman, A. M., Johnson, MD., Brown, W. R., and Bucci, T. J. (1998): Effect of dietary optimization on growth, survival, tumor incidences and clinical pathology parameters in CD Sprague-Dawley and Fischer-344 rats: a 104-week study. Drug Chem. Toxicol., 21: 97-117.
-
(1998)
Drug Chem. Toxicol
, vol.21
, pp. 97-117
-
-
Christian, M.S.1
Hoberman, A.M.2
Johnson, M.D.3
Brown, W.R.4
Bucci, T.J.5
-
43
-
-
0005150439
-
Interspecies differences in response to chemical carcinogens
-
edited by K. T. Kitchin, Marcel Dekker, New York
-
Clayson, D. B. and Kitchin, K. T. (1999): Interspecies differences in response to chemical carcinogens. In: Car-cinogenicity, edited by K. T. Kitchin, pp. 837-880. Marcel Dekker, New York.
-
(1999)
Car-cinogenicity
, pp. 837-880
-
-
Clayson, D.B.1
Kitchin, K.T.2
-
44
-
-
0031952171
-
Urinary bladder carcinogenesis
-
Cohen, S. M. (1998): Urinary bladder carcinogenesis. Toxicol. Pathol., 26:121-127.
-
(1998)
Toxicol. Pathol
, vol.26
, pp. 121-127
-
-
Cohen, S.M.1
-
45
-
-
0026316216
-
Genetic errors, cell proliferation, and carcinogenesis
-
Cohen, S. M. and Ellwein, L. B. (1991): Genetic errors, cell proliferation, and carcinogenesis. Cancer Res., 51: 6493-6505.
-
(1991)
Cancer Res
, vol.51
, pp. 6493-6505
-
-
Cohen, S.M.1
Ellwein, L.B.2
-
46
-
-
2342430116
-
Evaluating the human relevance of chemically induced animal tumors
-
Cohen, S. M., Klaunig, J., Meek, M. F., Hill, R. N., Pastoor, T. et al. (2004): Evaluating the human relevance of chemically induced animal tumors. Toxicol. Sci., 78:181-186.
-
(2004)
Toxicol. Sci
, vol.78
, pp. 181-186
-
-
Cohen, S.M.1
Klaunig, J.2
Meek, M.F.3
Hill, R.N.4
Pastoor, T.5
-
47
-
-
0242694978
-
Enzyme induction and dietary chemicals as approaches to cancer chemoprevention: The seventh DeWitt S. Goodman lecture
-
Conney, A. H. (2003); Enzyme induction and dietary chemicals as approaches to cancer chemoprevention: the seventh DeWitt S. Goodman lecture. Cancer Res., 63(21):7005-7031.
-
(2003)
Cancer Res
, vol.63
, Issue.21
, pp. 7005-7031
-
-
Conney, A.H.1
-
48
-
-
0028919282
-
A systemic exposure-based alternative to the maximum tolerated dose for carcinogenicity studies of human therapeutics
-
Contrera, J. F., Jacobs, A. C., Prasanna, H. R., Mehta, M., Schmidt, W. J., and DeGeorge, J. J. (1995): A systemic exposure-based alternative to the maximum tolerated dose for carcinogenicity studies of human therapeutics. J. Am. Coll. Toxicol, 14:1-10.
-
(1995)
J. Am. Coll. Toxicol
, vol.14
, pp. 1-10
-
-
Contrera, J.F.1
Jacobs, A.C.2
Prasanna, H.R.3
Mehta, M.4
Schmidt, W.J.5
DeGeorge, J.J.6
-
49
-
-
0011159198
-
-
Docket No. 96D-0235. U.S. Department of Health and Human Services, Public Health Service, Washington, D.C
-
Contrera, J. F., Jacobs, A. C., DeGeorge, J. J., Chen, C., Choudary, J. et al. (1996): Carcinogenicity Testing and the Evaluation of Regulatory Requirements for Pharmaceuticals, Docket No. 96D-0235. U.S. Department of Health and Human Services, Public Health Service, Washington, D.C.
-
(1996)
Carcinogenicity Testing and the Evaluation of Regulatory Requirements for Pharmaceuticals
-
-
Contrera, J.F.1
Jacobs, A.C.2
DeGeorge, J.J.3
Chen, C.4
Choudary, J.5
-
50
-
-
0031128199
-
Carcinogenicity testing and the evaluation of regulatory requirements for pharmaceuticals
-
Contrera, J. F., Jacobs, A. C., and DeGeorge, J. J. (1997): Carcinogenicity testing and the evaluation of regulatory requirements for pharmaceuticals. Regul. Toxicol. Pharmacol, 25:130-145.
-
(1997)
Regul. Toxicol. Pharmacol
, vol.25
, pp. 130-145
-
-
Contrera, J.F.1
Jacobs, A.C.2
DeGeorge, J.J.3
-
51
-
-
0242624535
-
Predicting the carcinogenic potential of pharmaceuticals in rodents using molecular structural similarity and E-state indices
-
Contrera, J. F., Matthews, E. J. and Benz, R. D. (2003): Predicting the carcinogenic potential of pharmaceuticals in rodents using molecular structural similarity and E-state indices. Regul. Toxicol. Pharmacol., 38:243-259.
-
(2003)
Regul. Toxicol. Pharmacol
, vol.38
, pp. 243-259
-
-
Contrera, J.F.1
Matthews, E.J.2
Benz, R.D.3
-
52
-
-
0032903895
-
Rodent Leydig cell tum-origenesis: A review of the physiology, pathology, mechanisms, and relevance to humans
-
Cook, J. C., Klinefelter, G. R., Hardisty, J. F., Sharpe, R. M., and Foster, P. M. D. (1999): Rodent Leydig cell tum-origenesis: a review of the physiology, pathology, mechanisms, and relevance to humans. Crit. Rev. Toxicol., 29: 169-261.
-
(1999)
Crit. Rev. Toxicol
, vol.29
, pp. 169-261
-
-
Cook, J.C.1
Klinefelter, G.R.2
Hardisty, J.F.3
Sharpe, R.M.4
Foster, P.M.D.5
-
53
-
-
0027939612
-
The dose-dependent effect of BHT (butylated hydroxytoluene) on vitamin K-dependent blood coagulation in rats
-
Cottrell, S., Andrews, C. M., Clayton, D., and Powell, C. J. (1994): The dose-dependent effect of BHT (butylated hydroxytoluene) on vitamin K-dependent blood coagulation in rats. Food Chem. Toxicol., 32(7):589-594.
-
(1994)
Food Chem. Toxicol
, vol.32
, Issue.7
, pp. 589-594
-
-
Cottrell, S.1
Andrews, C.M.2
Clayton, D.3
Powell, C.J.4
-
54
-
-
0029061206
-
Principles underlying dose selection for, and extrapolation from, the carcinogen bioassay: Dose influences mechanism
-
Counts, J. L. and Goodman, J. I. (1995): Principles underlying dose selection for, and extrapolation from, the carcinogen bioassay: dose influences mechanism. Regul. Toxicol. Pharmacol., 21:418-421.
-
(1995)
Regul. Toxicol. Pharmacol
, vol.21
, pp. 418-421
-
-
Counts, J.L.1
Goodman, J.I.2
-
55
-
-
0026450056
-
Immunohistochemical and ultrastructural characterization of granular cell tumors of the female reproductive tract in two aged Wistar rats
-
Courtney, C. L., Hawkins, K. L., Meierhenry, E. F., and Graziano, M. J. (1992): Immunohistochemical and ultrastructural characterization of granular cell tumors of the female reproductive tract in two aged Wistar rats. Vet. Pathol., 29:86-89
-
(1992)
Vet. Pathol
, vol.29
, pp. 86-89
-
-
Courtney, C.L.1
Hawkins, K.L.2
Meierhenry, E.F.3
Graziano, M.J.4
-
56
-
-
0000336139
-
Regression models and life tables
-
Cox, D. R. (1972): Regression models and life tables. J. R. Stat. Soc., 13:187-220.
-
(1972)
J. R. Stat. Soc
, vol.13
, pp. 187-220
-
-
Cox, D.R.1
-
57
-
-
1342302718
-
Best practices guideline: Toxicologic histopathology
-
Crissman, J. W., Goodman, D. G., Hildebrandt, P. K., Maronpot, R. R., Prater, D. A., Riley, J. H., Seaman, W. J., and Thake, D. C. (2004): Best practices guideline: toxicologic histopathology. Toxicol. Pathol., 32:126-131.
-
(2004)
Toxicol. Pathol
, vol.32
, pp. 126-131
-
-
Crissman, J.W.1
Goodman, D.G.2
Hildebrandt, P.K.3
Maronpot, R.R.4
Prater, D.A.5
Riley, J.H.6
Seaman, W.J.7
Thake, D.C.8
-
58
-
-
49749164498
-
Maximum utilization of life table method in analyzing survival
-
Cutler, S. J. and Ederer, F. (1958): Maximum utilization of life table method in analyzing survival. J. Chron. Dis., 8:699-712.
-
(1958)
J. Chron. Dis
, vol.8
, pp. 699-712
-
-
Cutler, S.J.1
Ederer, F.2
-
59
-
-
85132680946
-
-
Yokohama, Japan, 1995
-
D'Arcy, P. F. and Harron, D. W. G. (1996): Proceedings, Third International Conference on Harmonization, Yokohama, Japan, 1995.
-
(1996)
Proceedings, Third International Conference on Harmonization
-
-
D'Arcy, P.F.1
Harron, D.W.G.2
-
60
-
-
0028586775
-
The rodent carcino-genicity bioassay produces a similar frequency of tumor increases and decreases: Implications for risk assessment
-
Davies, T. S. and Monro, A. (1994): The rodent carcino-genicity bioassay produces a similar frequency of tumor increases and decreases: implications for risk assessment. Regul. Toxicol. Pharmacol., 20:281-301.
-
(1994)
Regul. Toxicol. Pharmacol
, vol.20
, pp. 281-301
-
-
Davies, T.S.1
Monro, A.2
-
61
-
-
0028902169
-
Marketed human pharmaceuticals reported to be tumorigenic in rodents
-
Davies, T. S. and Monro, A. (1995): Marketed human pharmaceuticals reported to be tumorigenic in rodents. J. Am. Coll. of Toxicol, 14:90-107.
-
(1995)
J. Am. Coll. of Toxicol
, vol.14
, pp. 90-107
-
-
Davies, T.S.1
Monro, A.2
-
62
-
-
0023033056
-
Interspecies scaling of regional drug delivery
-
Dedrick, R. L. (1986): Interspecies scaling of regional drug delivery. J. Pharmaceut. Sci, 175:1047-1052.
-
(1986)
J. Pharmaceut. Sci
, vol.175
, pp. 1047-1052
-
-
Dedrick, R.L.1
-
63
-
-
0001619236
-
A regulatory perspective of the guidance on the utility of two rodent species
-
edited by P. F. D'Arcy and D. W. G. Harron, Greystone Books, Antrim, North Ireland
-
DeGeorge, J. J. and Contrera, J. F. (1996): A regulatory perspective of the guidance on the utility of two rodent species. In: Proc. of the Third Int. Conf. on Harmonization, Yokohama, Japan, 1995, edited by P. F. D'Arcy and D. W. G. Harron, pp. 274-277. Greystone Books, Antrim, North Ireland.
-
(1996)
Proc. of the Third Int. Conf. on Harmonization, Yokohama, Japan, 1995
, pp. 274-277
-
-
DeGeorge, J.J.1
Contrera, J.F.2
-
64
-
-
0029328470
-
UV-induced skin cancer in a hairless mouse model
-
De Gruijl, F. R. and Forbes, P. D. (1995): UV-induced skin cancer in a hairless mouse model. BioEssays, 17:651-660.
-
(1995)
BioEssays
, vol.17
, pp. 651-660
-
-
de Gruijl, F.R.1
Forbes, P.D.2
-
65
-
-
0036186084
-
The value of historical control data: Scientific advantages for pathologists, industry and agencies
-
Deschl, U., Kittel, B., Rittinghausen, S., Morawietz, G., Kohler, M., Mohr, U., and Keenan, C. (2002): The value of historical control data: scientific advantages for pathologists, industry and agencies. Toxicol. Pathol., 30(1): 80-87.
-
(2002)
Toxicol. Pathol
, vol.30
, Issue.1
, pp. 80-87
-
-
Deschl, U.1
Kittel, B.2
Rittinghausen, S.3
Morawietz, G.4
Kohler, M.5
Mohr, U.6
Keenan, C.7
-
66
-
-
0031008928
-
Spontaneous liver tumours and benzo(a)pyrene-induced lymphomas in XPA-deficient mice
-
De Vries, A., von Oostrom, C. Th. M., Dortant, P. M., Beems, R. B., van Kriejl, C. F., Capel, P. J. A., and van Steeg, H. (1997): Spontaneous liver tumours and benzo(a)pyrene-induced lymphomas in XPA-deficient mice. Mol. Carcinog, 19:46-53.
-
(1997)
Mol. Carcinog
, vol.19
, pp. 46-53
-
-
de Vries, A.1
von Oostrom, C.T.M.2
Dortant, P.M.3
Beems, R.B.4
van Kriejl, C.F.5
Capel, P.J.A.6
van Steeg, H.7
-
67
-
-
2142702840
-
Differentiation of DNA reactive and non-reactive genotoxic mechanisms using gene expression profile analysis
-
Dickinson, D. A., Warnes, G. R., Quievzyn, G., Messer, J., Zhitkovich, A., Rubitski, E., and Aubrecht, J. (2004): Differentiation of DNA reactive and non-reactive genotoxic mechanisms using gene expression profile analysis. Mutat. Res., 549:29-41.
-
(2004)
Mutat. Res
, vol.549
, pp. 29-41
-
-
Dickinson, D.A.1
Warnes, G.R.2
Quievzyn, G.3
Messer, J.4
Zhitkovich, A.5
Rubitski, E.6
Aubrecht, J.7
-
68
-
-
0001821073
-
Carcinogenic effect on female rats after 12 month administration of the insulin analogue B10Asp
-
(abstract no. 507)
-
Dideriksen, L. H., Jorgensen, L. N., and Drejer, K. (1992): Carcinogenic effect on female rats after 12 month administration of the insulin analogue B10Asp. Diabetes, 41(Suppl. 1):143A (abstract no. 507).
-
(1992)
Diabetes
, vol.41
, pp. 143A
-
-
Dideriksen, L.H.1
Jorgensen, L.N.2
Drejer, K.3
-
69
-
-
33644789737
-
Topical application of representative multifunctional acrylates produced proliferative and inflammatory lesions in F344/N rats and B6C3F(1) mice, and squamous cell neoplasm in Tg.AC mice
-
Doi, A. M., Hailey, J. R., Hejtmancik, M., Toft, I. J. D., Vallant, M., and Chhabra, R. S. (2005): Topical application of representative multifunctional acrylates produced proliferative and inflammatory lesions in F344/N rats and B6C3F(1) mice, and squamous cell neoplasm in Tg.AC mice. Toxicol. Pathol, 33(6):631-640.
-
(2005)
Toxicol. Pathol
, vol.33
, Issue.6
, pp. 631-640
-
-
Doi, A.M.1
Hailey, J.R.2
Hejtmancik, M.3
Toft, I.J.D.4
Vallant, M.5
Chhabra, R.S.6
-
70
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors
-
Donehower, I., Harvey, M., Slagle, B. L., McArthur, M. J., Montgomery, Jr., C. A., Butel, J. S., and Bradley, A. (1992): Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors. Nature, 356: 215-221.
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, I.1
Harvey, M.2
Slagle, B.L.3
McArthur, M.J.4
Montgomery, C.A.5
Butel, J.S.6
Bradley, A.7
-
71
-
-
77957185391
-
An initiation-promotion assay in rat liver as a potential complement to the 2-year carcinogenesis bioassay
-
Dragan, Y. P., Rizvi, T., Xu, Y.-H., Hully, J. R., Bawa, N., Campbell, H. A., Maronpot, R. R., and Pitot, H. C. (1991): An initiation-promotion assay in rat liver as a potential complement to the 2-year carcinogenesis bioassay. Fun-dam. Appl. Toxicol, 16:525-547.
-
(1991)
Fun-dam. Appl. Toxicol
, vol.16
, pp. 525-547
-
-
Dragan, Y.P.1
Rizvi, T.2
Xu, Y.-H.3
Hully, J.R.4
Bawa, N.5
Campbell, H.A.6
Maronpot, R.R.7
Pitot, H.C.8
-
72
-
-
0009663357
-
A multiple comparison procedure for comparing several treatments with a control
-
Dunnett, C. W. (1955): A multiple comparison procedure for comparing several treatments with a control. J. Am. Stat. Assoc, 50:1096-1122.
-
(1955)
J. Am. Stat. Assoc
, vol.50
, pp. 1096-1122
-
-
Dunnett, C.W.1
-
73
-
-
0030980988
-
T25: A simplified carcinogenic potency index: Description of the system and study of correlations between carcinogenic potency and species/site specificity and mutagenicity
-
Dybing, E., Sanner, T., Roelfzema, H., Kroese, D., and Tennant, R. W. (1997): T25: A simplified carcinogenic potency index: description of the system and study of correlations between carcinogenic potency and species/site specificity and mutagenicity. Pharmacol. Toxicol, 30:272-279.
-
(1997)
Pharmacol. Toxicol
, vol.30
, pp. 272-279
-
-
Dybing, E.1
Sanner, T.2
Roelfzema, H.3
Kroese, D.4
Tennant, R.W.5
-
74
-
-
0028360826
-
Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and humans
-
Edwards, R. J., Murray, B. P., Murray, S., Schulz, T., Neubert, D., Gant, T. W., Thorgeirsson, S. S., Boobis, A. R., and Davis, D. S. (1994): Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and humans. Carcinogenesis, 15:829-836.
-
(1994)
Carcinogenesis
, vol.15
, pp. 829-836
-
-
Edwards, R.J.1
Murray, B.P.2
Murray, S.3
Schulz, T.4
Neubert, D.5
Gant, T.W.6
Thorgeirsson, S.S.7
Boobis, A.R.8
Davis, D.S.9
-
75
-
-
0033391436
-
Trends in mortality, body weights and tumor incidences of Wistar rats over 20 years
-
Eiben, R. and Bomhard, E. M. (1999): Trends in mortality, body weights and tumor incidences of Wistar rats over 20 years. Exp. Toxicol. Pathol, 51:523-536.
-
(1999)
Exp. Toxicol. Pathol
, vol.51
, pp. 523-536
-
-
Eiben, R.1
Bomhard, E.M.2
-
76
-
-
0025296895
-
The health risk of saccharin revisited
-
Ellwein, L. G. and Cohen, S. (1990): The health risk of saccharin revisited. CRC Crit. Rev. Toxicol, 20:311-326.
-
(1990)
CRC Crit. Rev. Toxicol
, vol.20
, pp. 311-326
-
-
Ellwein, L.G.1
Cohen, S.2
-
77
-
-
0029967755
-
Chemicals associated with decreases in the incidence of mononuclear cell leukemia in the Fischer rat
-
Elwell, M. R., Dunnick, J. K., Hailey, J. R., and Haseman, J. K. (1996): Chemicals associated with decreases in the incidence of mononuclear cell leukemia in the Fischer rat. Toxicol. Pathol., 24:238-245.
-
(1996)
Toxicol. Pathol
, vol.24
, pp. 238-245
-
-
Elwell, M.R.1
Dunnick, J.K.2
Hailey, J.R.3
Haseman, J.K.4
-
78
-
-
0025042320
-
Gender-related differences of serum thyroxine-binding proteins in the rat
-
Emerson, C. H., Cohen III, J. H., Young, R. A., Alex, S., and Fan, S.-L. (1990): Gender-related differences of serum thyroxine-binding proteins in the rat. Acta Endocrinol., 123:72-78.
-
(1990)
Acta Endocrinol
, vol.123
, pp. 72-78
-
-
Emerson, C.H.1
Cohen, J.H.2
Young, R.A.3
Alex, S.4
Fan, S.-L.5
-
79
-
-
0018428587
-
Does malignant hibernoma exist?
-
Enterline, H. T., Lowry, L. D., and Richman, A. V. (1979): Does malignant hibernoma exist? Am. J. Surg. Pathol., 3:265-271.
-
(1979)
Am. J. Surg. Pathol
, vol.3
, pp. 265-271
-
-
Enterline, H.T.1
Lowry, L.D.2
Richman, A.V.3
-
80
-
-
0032211432
-
Short- and intermediate-term carcinogenicity testing: A review. Part 1. The prototypes mouse skin tumour assay and rat liver focus
-
Enzmann, H., Bomhard, E., Iatropoulos, M. J., Ahr, H. J., Schlueter, G., and Williams, G. M. (1998): Short- and intermediate-term carcinogenicity testing: a review. Part 1. The prototypes mouse skin tumour assay and rat liver focus. Food Chem. Toxicol., 36:979-995.
-
(1998)
Food Chem. Toxicol
, vol.36
, pp. 979-995
-
-
Enzmann, H.1
Bomhard, E.2
Iatropoulos, M.J.3
Ahr, H.J.4
Schlueter, G.5
Williams, G.M.6
-
81
-
-
0032211455
-
Short- and intermediate-term carcinogenicity testing: A review. Part 2. Available experimental models
-
Enzmann, H., Iatropoulos, M. J., Brunnemann, K. D., Bomhard, E., Ahr, H. J., Schlueter, G., and Williams, G. M. (1998): Short- and intermediate-term carcinogenicity testing: a review. Part 2. Available experimental models. Food Chem. Toxicol., 36:997-1013.
-
(1998)
Food Chem. Toxicol
, vol.36
, pp. 997-1013
-
-
Enzmann, H.1
Iatropoulos, M.J.2
Brunnemann, K.D.3
Bomhard, E.4
Ahr, H.J.5
Schlueter, G.6
Williams, G.M.7
-
82
-
-
85132682065
-
-
Annex VI: Criteria for Classification of Carcinogenic Substances. European Economic Communities, Brussels, Belgium
-
EEC. (1967): Directive 67/548/EEC with Amendments and Adaptions. Annex VI: Criteria for Classification of Carcinogenic Substances. European Economic Communities, Brussels, Belgium.
-
(1967)
Directive 67/548/EEC with Amendments and Adaptions
-
-
-
87
-
-
0024358879
-
The trophic effect of luteinizing hormone on the rat Leydig cell
-
Ewing, L. L. (1989): The trophic effect of luteinizing hormone on the rat Leydig cell. J. Am. Coll. Toxicol., 8: 473-485.
-
(1989)
J. Am. Coll. Toxicol
, vol.8
, pp. 473-485
-
-
Ewing, L.L.1
-
88
-
-
0011152589
-
-
Elsevier, Amsterdam
-
Faccini, J. M., Abbott, D. P., and Paulus, G. J. J. (1990): Mouse Histopathology: A Glossary for Use in Toxicity and Carcinogenicity Studies, Elsevier, Amsterdam.
-
(1990)
Mouse Histopathology: A Glossary for Use in Toxicity and Carcinogenicity Studies
-
-
Faccini, J.M.1
Abbott, D.P.2
Paulus, G.J.J.3
-
89
-
-
0027103871
-
IFSTP guidelines for the design and interpretation of the chronic rodent carcinogenicity bioassay
-
Faccini, J. M., Butler, W. R., Friedmann, J.-C., Hess, R., Reznik, G. K., Ito, N., Hayashi, Y., and Williams, G. M. (1992): IFSTP guidelines for the design and interpretation of the chronic rodent carcinogenicity bioassay. Exp. Toxicol. Pathol., 44:443-456.
-
(1992)
Exp. Toxicol. Pathol
, vol.44
, pp. 443-456
-
-
Faccini, J.M.1
Butler, W.R.2
Friedmann, J.-C.3
Hess, R.4
Reznik, G.K.5
Ito, N.6
Hayashi, Y.7
Williams, G.M.8
-
90
-
-
0028918375
-
The comet assay: A comprehensive review
-
Fairbairn, D. W., Olive, P. L., and O'Neill, K. L. (1995): The comet assay: a comprehensive review. Mutat. Res., 339:37-59.
-
(1995)
Mutat. Res
, vol.339
, pp. 37-59
-
-
Fairbairn, D.W.1
Olive, P.L.2
O'Neill, K.L.3
-
91
-
-
50849153968
-
Clinical biostatistics
-
Feinstein, A. R. (1975): Clinical biostatistics. Clin. Pharmacol. Ther., 17:499-513.
-
(1975)
Clin. Pharmacol. Ther
, vol.17
, pp. 499-513
-
-
Feinstein, A.R.1
-
92
-
-
85132684486
-
Formulation of insoluble and immiscible test agents in liquid vehicles for toxicity testing
-
edited by C. W. Jameson and D. B. Walters. Butterworth, Stoneham, MA
-
Fitzgerald, J. M., Boy, V. F., and Manus, A. G. (1984): Formulation of insoluble and immiscible test agents in liquid vehicles for toxicity testing. In: Chemistry for Toxicity Testing, edited by C. W. Jameson and D. B. Walters. Butterworth, Stoneham, MA.
-
(1984)
Chemistry for Toxicity Testing
-
-
Fitzgerald, J.M.1
Boy, V.F.2
Manus, A.G.3
-
93
-
-
0030734835
-
Neonatal mouse assay for tumorigenicity: Alternative to the chronic rodent bioassay
-
Flammang, T. J., von Tungeln, L. S., Kadlubar, F. F., and Fu, P. P. (1997): Neonatal mouse assay for tumorigenicity: alternative to the chronic rodent bioassay. Regul. Toxicol. Pharmacol., 26:230-240.
-
(1997)
Regul. Toxicol. Pharmacol
, vol.26
, pp. 230-240
-
-
Flammang, T.J.1
von Tungeln, L.S.2
Kadlubar, F.F.3
Fu, P.P.4
-
97
-
-
0027249616
-
Photocarcinogenesis safety testing
-
Forbes, P. D., Sambuco, C. P., and Davies, R. E. (1993): Photocarcinogenesis safety testing. J. Am. Coll. Toxicol., 12:417-424.
-
(1993)
J. Am. Coll. Toxicol
, vol.12
, pp. 417-424
-
-
Forbes, P.D.1
Sambuco, C.P.2
Davies, R.E.3
-
98
-
-
0031666115
-
Assays for photocarcinogenesis: Relevance of animal models
-
Forbes P. D. and Sambuco C. P. (1998): Assays for photocarcinogenesis: relevance of animal models. Int. J. Toxicol., 17:577-588.
-
(1998)
Int. J. Toxicol
, vol.17
, pp. 577-588
-
-
Forbes, P.D.1
Sambuco, C.P.2
-
99
-
-
0028245103
-
The use of pharmacokinetics as an interpretive and predictive tool in chemical toxicology testing and risk assessment: A position paper on the appropriate use of pharmacokinetics in chemical toxicology
-
Frantz, S. W., Beatty, P. W., English, J. C., Hundley, S. G., and Wilson, A. G. E. (1994): The use of pharmacokinetics as an interpretive and predictive tool in chemical toxicology testing and risk assessment: a position paper on the appropriate use of pharmacokinetics in chemical toxicology. Reg. Toxicol. Pharmacol., 19:317-337.
-
(1994)
Reg. Toxicol. Pharmacol
, vol.19
, pp. 317-337
-
-
Frantz, S.W.1
Beatty, P.W.2
English, J.C.3
Hundley, S.G.4
Wilson, A.G.E.5
-
100
-
-
84947413985
-
Simultaneous test procedures for multiple comparisons on categorical data
-
Gabriel, K. (1966): Simultaneous test procedures for multiple comparisons on categorical data. J. Am. Stat. Assoc., 61:1081-1096.
-
(1966)
J. Am. Stat. Assoc
, vol.61
, pp. 1081-1096
-
-
Gabriel, K.1
-
101
-
-
0000705996
-
A simple method of multiple comparison of means
-
Gabriel, K. R. (1978): A simple method of multiple comparison of means. J. Am. Stat. Assoc., 73:724-729.
-
(1978)
J. Am. Stat. Assoc
, vol.73
, pp. 724-729
-
-
Gabriel, K.R.1
-
102
-
-
1542711927
-
Histologic and clinical pathology in the safety assessment and development of new therapeutic agents
-
Gad, S. C. (1996): Histologic and clinical pathology in the safety assessment and development of new therapeutic agents. Scand. J. Lab. Anim. Sci., 13:325-334.
-
(1996)
Scand. J. Lab. Anim. Sci
, vol.13
, pp. 325-334
-
-
Gad, S.C.1
-
103
-
-
0003538220
-
-
Telford Press, Caldwell, NJ
-
Gad, S. C. and Weil, C. S. (1986): Statistics and Experimental Design for Toxicologists, pp. 1-17. Telford Press, Caldwell, NJ.
-
(1986)
Statistics and Experimental Design for Toxicologists
, pp. 1-17
-
-
Gad, S.C.1
Weil, C.S.2
-
104
-
-
0032451385
-
Veterinary drugs no longer need testing for carcinogenicity in rodent bioassays
-
Galer, D. M. and Monro, A. M. (1998): Veterinary drugs no longer need testing for carcinogenicity in rodent bioassays. Regul. Toxicol. Pharmacol., 28:115-123.
-
(1998)
Regul. Toxicol. Pharmacol
, vol.28
, pp. 115-123
-
-
Galer, D.M.1
Monro, A.M.2
-
105
-
-
0028341175
-
Report from working group on in vitro tests for chromosomal aberrations
-
Galloway, S. M. et al. (1994): Report from working group on in vitro tests for chromosomal aberrations. Mutat. Res., 312:241-261.
-
(1994)
Mutat. Res
, vol.312
, pp. 241-261
-
-
Galloway, S.M.1
-
106
-
-
0023892372
-
Relationship between energy expenditure and body composition in man: Specific energy expenditure in vivo of fat and fat-free tissue
-
Garby, L., Garrow, J. S., Jorgensen, B., Lammert, O., Madsen, K., Sorensen, P., and Webster, J. (1988): Relationship between energy expenditure and body composition in man: specific energy expenditure in vivo of fat and fat-free tissue. Eur. J. Clin. Nutr., 42:301-305.
-
(1988)
Eur. J. Clin. Nutr
, vol.42
, pp. 301-305
-
-
Garby, L.1
Garrow, J.S.2
Jorgensen, B.3
Lammert, O.4
Madsen, K.5
Sorensen, P.6
Webster, J.7
-
107
-
-
0018761565
-
Statistical issues in the interpretation of chronic bioassay tests for carcinogenicity
-
Gart, J. J., Chu, K. C., and Tarone, R. E. (1979): Statistical issues in the interpretation of chronic bioassay tests for carcinogenicity. J. Natl. Cancer Inst., 62:957-974.
-
(1979)
J. Natl. Cancer Inst
, vol.62
, pp. 957-974
-
-
Gart, J.J.1
Chu, K.C.2
Tarone, R.E.3
-
108
-
-
0033000250
-
Dose-response trend tests for tumorigenesis, adjusted for body weight
-
Gaylor, D. W. and Kodell, R. I. (1999): Dose-response trend tests for tumorigenesis, adjusted for body weight. Toxicol. Sci., 49:318-323.
-
(1999)
Toxicol. Sci
, vol.49
, pp. 318-323
-
-
Gaylor, D.W.1
Kodell, R.I.2
-
109
-
-
0018187901
-
Resolution of dose response toxicity data for chemicals requiring metabolic activation-example: Vinyl chloride
-
Gehring, P. J., Watanabe, P. G., and Park, C. N. (1978): Resolution of dose response toxicity data for chemicals requiring metabolic activation-example: vinyl chloride. Toxicol. Appl. Pharmacol., 44:581-591.
-
(1978)
Toxicol. Appl. Pharmacol
, vol.44
, pp. 581-591
-
-
Gehring, P.J.1
Watanabe, P.G.2
Park, C.N.3
-
110
-
-
0025695989
-
Correlation between acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and total body fat content in mammals
-
Geyer, H. J., Scheuntert, I., Rapp, K., Kettrup, A., Korte, F., Greim, H., and Rozman, K. (1990): Correlation between acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and total body fat content in mammals. Toxicology, 65(1-2):97-107.
-
(1990)
Toxicology
, vol.65
, Issue.1-2
, pp. 97-107
-
-
Geyer, H.J.1
Scheuntert, I.2
Rapp, K.3
Kettrup, A.4
Korte, F.5
Greim, H.6
Rozman, K.7
-
115
-
-
20544448220
-
Supplement to the Carcinogenic Potency Database (CPDB): Results of animal bioassays published in the general literature through 1997 and by the National Toxicology Program in 1997-1998
-
Gold, L. S. et al. (2005): Supplement to the Carcinogenic Potency Database (CPDB): results of animal bioassays published in the general literature through 1997 and by the National Toxicology Program in 1997-1998. Toxicol. Sci., 85:745-808.
-
(2005)
Toxicol. Sci
, vol.85
, pp. 745-808
-
-
Gold, L.S.1
-
116
-
-
0003698284
-
-
MTP Press, Lancaster, U.K
-
Gopinath, C., Prentice, D. E., and Lewis, D. J. (1987): Atlas of Experimental Toxicological Pathology. MTP Press, Lancaster, U.K.
-
(1987)
Atlas of Experimental Toxicological Pathology
-
-
Gopinath, C.1
Prentice, D.E.2
Lewis, D.J.3
-
117
-
-
0013914092
-
Subcutaneous sarcoma as an index of carcinogenic potency
-
Grasso, P. and Golberg, L. (1966): Subcutaneous sarcoma as an index of carcinogenic potency. Food Cosmet. Toxicol., 4:297-320.
-
(1966)
Food Cosmet. Toxicol
, vol.4
, pp. 297-320
-
-
Grasso, P.1
Golberg, L.2
-
118
-
-
0025878351
-
Role of persistent, non-genotoxic tissue damage in rodent cancer and relevance to humans
-
Grasso, P., Sharratt, M., and Cohen, A. J. (1991): Role of persistent, non-genotoxic tissue damage in rodent cancer and relevance to humans. Annu. Rev. Pharmacol. Toxicol., 31:253-287.
-
(1991)
Annu. Rev. Pharmacol. Toxicol
, vol.31
, pp. 253-287
-
-
Grasso, P.1
Sharratt, M.2
Cohen, A.J.3
-
120
-
-
0344898209
-
Evaluation of historical control data in carcinogenicity studies
-
Greim, H., Gelbke, H. P., Reuter, U., Thielmann, H. W., and Edler, L. (2003): Evaluation of historical control data in carcinogenicity studies. Hum. Exp. Toxicol., 22(10): 541-549.
-
(2003)
Hum. Exp. Toxicol
, vol.22
, Issue.10
, pp. 541-549
-
-
Greim, H.1
Gelbke, H.P.2
Reuter, U.3
Thielmann, H.W.4
Edler, L.5
-
122
-
-
0031887832
-
Submucosal mesenchymal tumors of the mouse urinary bladder
-
Halliwell, W. H. (1998): Submucosal mesenchymal tumors of the mouse urinary bladder. Toxicol. Pathol., 26:128-136.
-
(1998)
Toxicol. Pathol
, vol.26
, pp. 128-136
-
-
Halliwell, W.H.1
-
123
-
-
0028349086
-
Selective inhibitors of cytochrome P450
-
Halpert, J. R., Guengerich, F. P., Bend, J. R., and Correia, M. A. (1994): Selective inhibitors of cytochrome P450. Toxicol. Appl. Pharmacol., 124:163-175.
-
(1994)
Toxicol. Appl. Pharmacol
, vol.124
, pp. 163-175
-
-
Halpert, J.R.1
Guengerich, F.P.2
Bend, J.R.3
Correia, M.A.4
-
124
-
-
77957175489
-
Caloric restriction and toxicology
-
Hart, R. W., Keenan, K. P., Turturro, A., Abdo, K. M., Leakey, J., and Lyn-Cook, L. (1995): Caloric restriction and toxicology. Fundam. Appl. Toxicol., 25:184-195.
-
(1995)
Fundam. Appl. Toxicol
, vol.25
, pp. 184-195
-
-
Hart, R.W.1
Keenan, K.P.2
Turturro, A.3
Abdo, K.M.4
Leakey, J.5
Lyn-Cook, L.6
-
125
-
-
0004170867
-
-
ILSI Press, Washington, D.C
-
Hart, R. W., Neumann, D. A., and Robertson, R. T. (1995): Dietary Restriction: Implications for the Design and Interpretation of Toxicity and Carcinogenicity Studies. ILSI Press, Washington, D.C.
-
(1995)
Dietary Restriction: Implications for the Design and Interpretation of Toxicity and Carcinogenicity Studies
-
-
Hart, R.W.1
Neumann, D.A.2
Robertson, R.T.3
-
126
-
-
0021647477
-
Statistical issues in the design analysis and interpretation of animal carcinogenicity studies
-
Haseman, J. K. (1984): Statistical issues in the design analysis and interpretation of animal carcinogenicity studies. Environ. Health Persp., 58:385-392.
-
(1984)
Environ. Health Persp
, vol.58
, pp. 385-392
-
-
Haseman, J.K.1
-
127
-
-
0025284446
-
Use of statistical decision rules for evaluating laboratory animal carcinogenicity studies
-
Haseman, J. K. (1990): Use of statistical decision rules for evaluating laboratory animal carcinogenicity studies. Fundam. Appl. Toxicol., 14:637-648.
-
(1990)
Fundam. Appl. Toxicol
, vol.14
, pp. 637-648
-
-
Haseman, J.K.1
-
128
-
-
0021148721
-
Use of historical control data in carcinogenicity studies in rodents
-
Haseman, J. K., Huff, J., and Boorman, G. A. (1984): Use of historical control data in carcinogenicity studies in rodents. Toxicol. Pathol., 2:126-135.
-
(1984)
Toxicol. Pathol
, vol.2
, pp. 126-135
-
-
Haseman, J.K.1
Huff, J.2
Boorman, G.A.3
-
129
-
-
77957186342
-
Use of dual control groups to estimate false positive rates in laboratory animal carcinogenicity studies
-
Haseman, J. K., Winbush, J. S., and O'Donnell, Jr., M. W. (1986): Use of dual control groups to estimate false positive rates in laboratory animal carcinogenicity studies. Fundam. Appl. Toxicol., 7:573-584.
-
(1986)
Fundam. Appl. Toxicol
, vol.7
, pp. 573-584
-
-
Haseman, J.K.1
Winbush, J.S.2
O'Donnell, M.W.3
-
130
-
-
0026728595
-
Effects of corn oil, time-related changes, and inter-laboratory variability on tumor occurrence in control Fischer 344 (F344/N) rats
-
Haseman, J. K. and Rao, G. N. (1992): Effects of corn oil, time-related changes, and inter-laboratory variability on tumor occurrence in control Fischer 344 (F344/N) rats. Toxicol. Pathol., 20:52-60.
-
(1992)
Toxicol. Pathol
, vol.20
, pp. 52-60
-
-
Haseman, J.K.1
Rao, G.N.2
-
131
-
-
77957187759
-
The relationship between use of the maximum tolerated dose and study sensitivity for detecting rodent carcinogenicity
-
Haseman, J. K. and Lockhart, A. (1994): The relationship between use of the maximum tolerated dose and study sensitivity for detecting rodent carcinogenicity. Fundam. Appl. Toxicol., 22:382-391.
-
(1994)
Fundam. Appl. Toxicol
, vol.22
, pp. 382-391
-
-
Haseman, J.K.1
Lockhart, A.2
-
132
-
-
0030060456
-
Analysis of National Toxicology Program rodent bioassay data for anticarcinogenic effects
-
Haseman, J. K. and Johnson, L. (1996): Analysis of National Toxicology Program rodent bioassay data for anticarcinogenic effects. Mutat. Res., 350:131-141.
-
(1996)
Mutat. Res
, vol.350
, pp. 131-141
-
-
Haseman, J.K.1
Johnson, L.2
-
133
-
-
0031955224
-
1 mice in two-year carcinogenicity studies: A National Toxicology Program update
-
1 mice in two-year carcinogenicity studies: a National Toxicology Program update. Toxicol. Pathol., 26: 428-441.
-
(1998)
Toxicol. Pathol
, vol.26
, pp. 428-441
-
-
Haseman, J.K.1
Hailey, J.R.2
Morris, R.W.3
-
134
-
-
0242721397
-
Effect of diet and animal care/housing protocols on body weight, survival, tumor incidences, and nephropathy severity of F344 rats in chronic studies
-
Haseman, J. K., Ney, E., Nyska, A., and Rao, G. N. (2003): Effect of diet and animal care/housing protocols on body weight, survival, tumor incidences, and nephropathy severity of F344 rats in chronic studies. Toxicol. Pathol., 31: 674-681.
-
(2003)
Toxicol. Pathol
, vol.31
, pp. 674-681
-
-
Haseman, J.K.1
Ney, E.2
Nyska, A.3
Rao, G.N.4
-
135
-
-
18044376877
-
Age-related differences in susceptibility to carcinogenesis. II. Approaches for application and uncertainty analyses for individual genetically acting carcinogens
-
Hattis, D., Goble, R., and Chu, M. (2005): Age-related differences in susceptibility to carcinogenesis. II. Approaches for application and uncertainty analyses for individual genetically acting carcinogens. Environ. Health Perspect., 113:509-516.
-
(2005)
Environ. Health Perspect
, vol.113
, pp. 509-516
-
-
Hattis, D.1
Goble, R.2
Chu, M.3
-
137
-
-
0035996081
-
Rodent carcinogenicity with the thiazolidinedione antidiabetic agent troglitazone
-
Herman, J. R., Dethloff, L. A., McGuire, E. J., Parker, R. F., Walsh, K. M., Gough, A. W., Masuda, H., and de la Iglesia, F. A. (2002): Rodent carcinogenicity with the thiazolidinedione antidiabetic agent troglitazone. Toxicol. Sci. 68:195-235.
-
(2002)
Toxicol. Sci
, vol.68
, pp. 195-235
-
-
Herman, J.R.1
Dethloff, L.A.2
McGuire, E.J.3
Parker, R.F.4
Walsh, K.M.5
Gough, A.W.6
Masuda, H.7
de la Iglesia, F.A.8
-
138
-
-
85132684716
-
Effect of day vs. night inhalation exposure on lung burdens of galliumoxide in rats
-
Inhalation Toxicology Research Institute, Albuquerque, NM
-
Hesseltine, G. R., Wolff, R. K., Hanson, R. L., Mauderly, J. L., and McClellan, R. O. (1984): Effect of day vs. night inhalation exposure on lung burdens of galliumoxide in rats. In: Inhalation Toxicology Research Institute Annual Report. Inhalation Toxicology Research Institute, Albuquerque, NM.
-
(1984)
Inhalation Toxicology Research Institute Annual Report
-
-
Hesseltine, G.R.1
Wolff, R.K.2
Hanson, R.L.3
Mauderly, J.L.4
McClellan, R.O.5
-
139
-
-
0031656005
-
Risk assessment of thyroid follicular cell tumors
-
Hill, R. N., Crisp, T. M., Hurley, P. M., Rosenthal, S. L., and Singh, D. V. (1998): Risk assessment of thyroid follicular cell tumors. Environ. Health Perspect., 106: 447-457.
-
(1998)
Environ. Health Perspect
, vol.106
, pp. 447-457
-
-
Hill, R.N.1
Crisp, T.M.2
Hurley, P.M.3
Rosenthal, S.L.4
Singh, D.V.5
-
140
-
-
0028878453
-
Role of brown adipose tissue thermogenesis in control of thermoregulatory feeding in rats: A new hypothesis that links thermostatic and glucostatic hypotheses for control of food intake
-
Himms-Hagen, J. (1995): Role of brown adipose tissue thermogenesis in control of thermoregulatory feeding in rats: a new hypothesis that links thermostatic and glucostatic hypotheses for control of food intake. Proc. Soc. Exp. Biol. Med., 208:159-169.
-
(1995)
Proc. Soc. Exp. Biol. Med
, vol.208
, pp. 159-169
-
-
Himms-Hagen, J.1
-
141
-
-
29544450979
-
Mode of action in relevance of rodent liver tumors to human cancer risk
-
Holsapple, M. P., Pitot, H. C., Cohen, S. H., Boobis, A. R., Klaunig, J. E., Pastoor, T., Dellarco, V. L., and Dragan, Y. P. (2006): Mode of action in relevance of rodent liver tumors to human cancer risk. Toxicol. Sci., 89(1):51-56.
-
(2006)
Toxicol. Sci
, vol.89
, Issue.1
, pp. 51-56
-
-
Holsapple, M.P.1
Pitot, H.C.2
Cohen, S.H.3
Boobis, A.R.4
Klaunig, J.E.5
Pastoor, T.6
Dellarco, V.L.7
Dragan, Y.P.8
-
142
-
-
0021666075
-
Appropriateness of methods for slide evaluation in the practice of toxicologic pathology
-
Iatropoulos, M. J. (1984): Appropriateness of methods for slide evaluation in the practice of toxicologic pathology. Toxicol. Pathol., 12:4-5.
-
(1984)
Toxicol. Pathol
, vol.12
, pp. 4-5
-
-
Iatropoulos, M.J.1
-
143
-
-
85073994394
-
Society of Toxicologic Pathologists position paper: 'blinded' microscopic examination of tissues from toxicologic or oncogenic studies
-
edited by H. C. Grice and J. L. Ciminera, Springer-Verlag, New York
-
Iatropoulos, M. J. (1988): Society of Toxicologic Pathologists position paper: 'blinded' microscopic examination of tissues from toxicologic or oncogenic studies. In: Carcinogenicity, edited by H. C. Grice and J. L. Ciminera, pp. 133-135. Springer-Verlag, New York.
-
(1988)
Carcinogenicity
, pp. 133-135
-
-
Iatropoulos, M.J.1
-
144
-
-
0002921423
-
Comparative histokinetic and xenodynamic considerations in toxicity
-
edited by D. G. P. Welling and F. A. de la Iglesia, Marcel Dekker, New York
-
Iatropoulos, M. J. (1993): Comparative histokinetic and xenodynamic considerations in toxicity. In: Drug Toxicokinetics, edited by D. G. P. Welling and F. A. de la Iglesia, pp. 245-266. Marcel Dekker, New York.
-
(1993)
Drug Toxicokinetics
, pp. 245-266
-
-
Iatropoulos, M.J.1
-
145
-
-
0028297704
-
Endocrine considerations in toxicologic pathology
-
Iatropoulos, M. J. (1994): Endocrine considerations in toxicologic pathology. Exp. Toxicol. Pathol., 45:391-410.
-
(1994)
Exp. Toxicol. Pathol
, vol.45
, pp. 391-410
-
-
Iatropoulos, M.J.1
-
146
-
-
0028090180
-
Urinary bladder hyperplasia in the rat: Non-specific pathogenetic considerations using a beta-lactam antibiotic
-
Iatropoulos, M. J., Newman, A. J., Dayan, A. D., Brughera, M., Scampini, G., and Mazue, G. (1994): Urinary bladder hyperplasia in the rat: non-specific pathogenetic considerations using a beta-lactam antibiotic. Exp. Toxicol. Pathol., 46:265-274.
-
(1994)
Exp. Toxicol. Pathol
, vol.46
, pp. 265-274
-
-
Iatropoulos, M.J.1
Newman, A.J.2
Dayan, A.D.3
Brughera, M.4
Scampini, G.5
Mazue, G.6
-
147
-
-
3242871406
-
New histopathologic and histokinetic methods in preclinical safety studies
-
Iatropoulos, M. J., Williams, G. M., Wang, C.-X., and Karlsson, S. H. (1996): New histopathologic and histokinetic methods in preclinical safety studies. Scand. J. Lab. Anim. Sci., 13:339-343.
-
(1996)
Scand. J. Lab. Anim. Sci
, vol.13
, pp. 339-343
-
-
Iatropoulos, M.J.1
Williams, G.M.2
Wang, C.-X.3
Karlsson, S.H.4
-
149
-
-
18144404047
-
The function and pathology of brown adipose tissue in animals and humans
-
Iatropoulos, M. and Williams, G. (2004): The function and pathology of brown adipose tissue in animals and humans. J. Toxicol. Pathol., 17:147-153.
-
(2004)
J. Toxicol. Pathol
, vol.17
, pp. 147-153
-
-
Iatropoulos, M.1
Williams, G.2
-
150
-
-
1842305476
-
Effects of dietary restriction on age-associated pathological changes in F-344 rats
-
Imai, K., Yoshimura, S., Yamaguchi, K., Matsui, E., Isaka, H., and Hashimoto, K. (1990): Effects of dietary restriction on age-associated pathological changes in F-344 rats. J. Toxicol. Pathol., 3:209-221.
-
(1990)
J. Toxicol. Pathol
, vol.3
, pp. 209-221
-
-
Imai, K.1
Yoshimura, S.2
Yamaguchi, K.3
Matsui, E.4
Isaka, H.5
Hashimoto, K.6
-
151
-
-
0021182518
-
Criteria for evidence of chemical carcinogenicity
-
Interdisciplinary Panel on Carcinogenicity (IPC/AIHC). (1984): Criteria for evidence of chemical carcinogenicity. Science, 225:682-687.
-
(1984)
Science
, vol.225
, pp. 682-687
-
-
-
154
-
-
0004160916
-
-
IARC Publ. No. 104. International Agency for Research on Cancer, Lyon, France
-
IARC. (1990): Complex Mixtures and Cancer Risk, IARC Publ. No. 104. International Agency for Research on Cancer, Lyon, France.
-
(1990)
Complex Mixtures and Cancer Risk
-
-
-
155
-
-
0003937031
-
-
IARC Publ. No. 116. International Agency for Research on Cancer, Lyon, France
-
IARC. (1992): Mechanisms of Carcinogenesis in Risk Identification, IARC Publ. No. 116. International Agency for Research on Cancer, Lyon, France.
-
(1992)
Mechanisms of Carcinogenesis in Risk Identification
-
-
-
156
-
-
0003459739
-
-
IARC Tech. Rep. No. 55. International Agency for Research on Cancer, Lyon, France
-
IARC. (1992): Solar and Ultraviolet Radiation, IARC Tech. Rep. No. 55. International Agency for Research on Cancer, Lyon, France.
-
(1992)
Solar and Ultraviolet Radiation
-
-
-
158
-
-
85132679807
-
-
IARC Publ. No. 134. International Agency for Research on Cancer, Lyon, France
-
IARC. (1996): Directory of Agents Being Tested for Carcinogenicity, IARC Publ. No. 134. International Agency for Research on Cancer, Lyon, France.
-
(1996)
Directory of Agents Being Tested for Carcinogenicity
-
-
-
161
-
-
85132685321
-
Benzofuran, pp. 27-30; Butylated hydroxy-anisole, pp. 31-40; Dichlorovos, pp. 49-56
-
IARC Tech. Publ. No. 39. International Agency for Research on Cancer, Lyon, France
-
IARC. (2003): Benzofuran, pp. 27-30; Butylated hydroxy-anisole, pp. 31-40; Dichlorovos, pp. 49-56. In: IARC Monographs in the Predictive Value of Rodent Forestomach and Gastric Neuroendocrine Tumours in Evaluating Carcinogenic Risks to Humans, IARC Tech. Publ. No. 39. International Agency for Research on Cancer, Lyon, France.
-
(2003)
IARC Monographs in the Predictive Value of Rodent Forestomach and Gastric Neuroendocrine Tumours in Evaluating Carcinogenic Risks to Humans
-
-
-
162
-
-
0038394851
-
-
International Agency for Research on Cancer, Lyon, France
-
IARC. (2003): World Cancer Report. International Agency for Research on Cancer, Lyon, France.
-
(2003)
World Cancer Report
-
-
-
163
-
-
85132679786
-
-
Commission of the European Communities, Directorate General III: Industry: Industrial Affairs III: Consumer Goods Industries: Pharmaceuticals. International Conference on Harmonization, Brussels, Belgium
-
ICH. (1994): Guideline III/5081 on Toxicokinetics, Commission of the European Communities, Directorate General III: Industry: Industrial Affairs III: Consumer Goods Industries: Pharmaceuticals. International Conference on Harmonization, Brussels, Belgium.
-
(1994)
Guideline III/5081 on Toxicokinetics
-
-
-
165
-
-
85132689151
-
-
Recommended for Adoption of Step 4 of the ICH Process on October 27, 1994, by the ICH Steering Committee and Addendum on the Limit Dose Related to Dose Selection for Carcinogenicity Studies of Pharmaceuticals, Step 4 Consensus Guideline. International Conference on Harmonization, Brussels, Belgium
-
ICH. (1997): ICH Harmonized Tripartite Guideline: Dose Selection for Carcinogenicity Studies of Pharmaceuticals, Recommended for Adoption of Step 4 of the ICH Process on October 27, 1994, by the ICH Steering Committee and Addendum on the Limit Dose Related to Dose Selection for Carcinogenicity Studies of Pharmaceuticals, Step 4 Consensus Guideline. International Conference on Harmonization, Brussels, Belgium.
-
(1997)
ICH Harmonized Tripartite Guideline: Dose Selection for Carcinogenicity Studies of Pharmaceuticals
-
-
-
166
-
-
0029780851
-
The use of mechanistic data in the risk assessments of ten chemicals: An introduction to the chemical-specific reviews
-
International Expert Panel on Carcinogen Risk Assessment (IEPCRA). (1996): The use of mechanistic data in the risk assessments of ten chemicals: an introduction to the chemical-specific reviews. Pharmacol. Ther, 71:1-5.
-
(1996)
Pharmacol. Ther
, vol.71
, pp. 1-5
-
-
-
167
-
-
0011002692
-
Alternatives to carcinogenicity testing
-
International Life Sciences Institute (ILSI); Health and Environmental Sciences Institute (HESI). (2001): Alternatives to carcinogenicity testing. Toxicol. Pathol., 29(Suppl.): 1-351.
-
(2001)
Toxicol. Pathol
, vol.29
, pp. 1-351
-
-
-
168
-
-
0040921537
-
Butylated hydroxytoluene (BHT)
-
prepared by the Expert Committee on Food Additives (JECFA) for the 4th Joint Meeting of FAO/WHO, International Programme on Chemical Safety, World Health Organization, Geneva
-
IPCS. (1996): Butylated hydroxytoluene (BHT). In: Toxicological Evaluation of Certain Food Additives and Contaminants, prepared by the Expert Committee on Food Additives (JECFA) for the 4th Joint Meeting of FAO/WHO, pp. 3-86. International Programme on Chemical Safety, World Health Organization, Geneva.
-
(1996)
Toxicological Evaluation of Certain Food Additives and Contaminants
, pp. 3-86
-
-
-
169
-
-
34047163212
-
-
International Programme on Chemical Safety, World Health Organization, Geneva
-
IPCS. (2004): IPCS Risk Assessment Terminology. International Programme on Chemical Safety, World Health Organization, Geneva.
-
(2004)
IPCS Risk Assessment Terminology
-
-
-
170
-
-
0027015714
-
Clinical pathology testing in preclinical safety assessment
-
International Workshop. (1992): Clinical pathology testing in preclinical safety assessment. Toxicol. Pathol., 20: 469-543.
-
(1992)
Toxicol. Pathol
, vol.20
, pp. 469-543
-
-
-
171
-
-
27644441505
-
Prediction of 2-year carcinogenicity study results for pharmaceutical products: How are we doing?
-
Jacobs, A. (2005): Prediction of 2-year carcinogenicity study results for pharmaceutical products: how are we doing? Toxicol. Sci, 88(1):18-23.
-
(2005)
Toxicol. Sci
, vol.88
, Issue.1
, pp. 18-23
-
-
Jacobs, A.1
-
172
-
-
0032939052
-
Does photosensitivity predict photococarcinogenicity?
-
Jacobs, A., Avalos, J., Brown, P., and Wilkin, J. (1999): Does photosensitivity predict photococarcinogenicity? Int. J. Toxicol, 18:191-198.
-
(1999)
Int. J. Toxicol
, vol.18
, pp. 191-198
-
-
Jacobs, A.1
Avalos, J.2
Brown, P.3
Wilkin, J.4
-
173
-
-
0019770980
-
Kinetics of intake, distribution and excretion of zinc in rats
-
Jain, R. K., Gerlowski, L. E., Weissbrod, J. M., Wang, J., and Pierson, Jr., R. N. (1981): Kinetics of intake, distribution and excretion of zinc in rats. Ann. Biomed. Eng., 9: 345-361.
-
(1981)
Ann. Biomed. Eng
, vol.9
, pp. 345-361
-
-
Jain, R.K.1
Gerlowski, L.E.2
Weissbrod, J.M.3
Wang, J.4
Pierson, R.N.5
-
174
-
-
84989145121
-
Analytical chemistry requirements for toxicity testing of environmental chemicals
-
edited by C. W. Jameson and D. B. Walters, Butterworth, Stoneham, MA
-
Jameson, C. W. (1984): Analytical chemistry requirements for toxicity testing of environmental chemicals. In: Chemistry for Toxicity Testing, edited by C. W. Jameson and D. B. Walters, Butterworth, Stoneham, MA.
-
(1984)
Chemistry for Toxicity Testing
-
-
Jameson, C.W.1
-
175
-
-
0013849280
-
Enzootic intestinal adenocarcinoma in hamsters
-
Jonas, A. M., Tomita, Y., and Wyand, D. S. (1965): Enzootic intestinal adenocarcinoma in hamsters. J. Am. Vet. Med. Assoc, 147:1102-1108.
-
(1965)
J. Am. Vet. Med. Assoc
, vol.147
, pp. 1102-1108
-
-
Jonas, A.M.1
Tomita, Y.2
Wyand, D.S.3
-
176
-
-
0027102080
-
FDA requirements for nonclinical testing of contraceptive steroids
-
Jordan, A. (1992): FDA requirements for nonclinical testing of contraceptive steroids. Contraception., 46:499-509.
-
(1992)
Contraception
, vol.46
, pp. 499-509
-
-
Jordan, A.1
-
177
-
-
0033024823
-
'Mesenchymal tumor' or 'decidual-like reaction'?
-
Karbe, E. (1999): 'Mesenchymal tumor' or 'decidual-like reaction'? Toxicol. Pathol, 27:354-362.
-
(1999)
Toxicol. Pathol
, vol.27
, pp. 354-362
-
-
Karbe, E.1
-
178
-
-
0031680191
-
Similarities between the uterine decidual reaction and the 'mesenchymal lesion' of the urinary bladder in aging mice
-
Karbe, E., Hartmann, E., George, C., Wadsworth, P., Har-leman, J. and Geiss, V. (1998): Similarities between the uterine decidual reaction and the 'mesenchymal lesion' of the urinary bladder in aging mice. Exp. Toxicol. Pathol., 50:4-6.
-
(1998)
Exp. Toxicol. Pathol
, vol.50
, pp. 4-6
-
-
Karbe, E.1
Hartmann, E.2
George, C.3
Wadsworth, P.4
Har-leman, J.5
Geiss, V.6
-
179
-
-
10844254687
-
Assessment and acceptance of thresholds of genotoxic impurities in new drug substances: A regulatory perspective
-
Kasper, P. (2004): Assessment and acceptance of thresholds of genotoxic impurities in new drug substances: a regulatory perspective. Int. J. Pharmaceut. Med., 18: 209-214.
-
(2004)
Int. J. Pharmaceut. Med
, vol.18
, pp. 209-214
-
-
Kasper, P.1
-
180
-
-
0030138572
-
The uncontrolled variable in risk assessment: Ad libitum overfed rodents - fat, facts and fiction
-
Keenan, K. P. (1996): The uncontrolled variable in risk assessment: ad libitum overfed rodents - fat, facts and fiction. Toxicol. Pathol., 24:376-383.
-
(1996)
Toxicol. Pathol
, vol.24
, pp. 376-383
-
-
Keenan, K.P.1
-
181
-
-
0028037628
-
The effects of overfeeding and dietary restriction on Sprague-Dawley rat survival and early pathology biomarkers of aging
-
Keenan, K., Smith, P., Hertzog, P., Soper, K., Ballam, G., and Clark, R. (1994): The effects of overfeeding and dietary restriction on Sprague-Dawley rat survival and early pathology biomarkers of aging. Toxicol. Pathol., 22:300-331.
-
(1994)
Toxicol. Pathol
, vol.22
, pp. 300-331
-
-
Keenan, K.1
Smith, P.2
Hertzog, P.3
Soper, K.4
Ballam, G.5
Clark, R.6
-
182
-
-
0030451167
-
The effects of diet, ad libitum overfeeding, and moderate dietary restriction on the rodent bioassay: The uncontrolled variable in safety assessment
-
Keenan, K. P. Laroque, P., Ballam, G. C., Soper, K. A., Dixit, R., Mattson, B. A., Adams, S. P., and Coleman, J. B. (1996): The effects of diet, ad libitum overfeeding, and moderate dietary restriction on the rodent bioassay: the uncontrolled variable in safety assessment. Toxicol. Pathol., 24:757-768.
-
(1996)
Toxicol. Pathol
, vol.24
, pp. 757-768
-
-
Keenan, K.P.1
Laroque, P.2
Ballam, G.C.3
Soper, K.A.4
Dixit, R.5
Mattson, B.A.6
Adams, S.P.7
Coleman, J.B.8
-
183
-
-
0027196603
-
Drug-induced mesovarial leiomyomas in the rat: A review and additional data
-
Kelly, W. A., Marler, R. J., and Weikel, J. H. (1993): Drug-induced mesovarial leiomyomas in the rat: a review and additional data. J. Am. Coll. Toxicol., 12: 13-22.
-
(1993)
J. Am. Coll. Toxicol
, vol.12
, pp. 13-22
-
-
Kelly, W.A.1
Marler, R.J.2
Weikel, J.H.3
-
184
-
-
0028936624
-
Hepatocarcinogenesis in p53-defi-cient mice
-
Kemp, C. J. (1995): Hepatocarcinogenesis in p53-defi-cient mice. Mol. Carcinog., 12:132-136.
-
(1995)
Mol. Carcinog
, vol.12
, pp. 132-136
-
-
Kemp, C.J.1
-
185
-
-
0012583173
-
-
AFIP, Washington, D.C
-
Kempson, R. L., Fletcher, C. D. M., Evans, H. L., Hendrickson, M. R., and Sibley, R. K. (2001): Tumours of the Soft Tissues: Atlas of Tumour Pathology, pp. 195-235. AFIP, Washington, D.C.
-
(2001)
Tumours of the Soft Tissues: Atlas of Tumour Pathology
, pp. 195-235
-
-
Kempson, R.L.1
Fletcher, C.D.M.2
Evans, H.L.3
Hendrickson, M.R.4
Sibley, R.K.5
-
186
-
-
11144355440
-
Applications of microarrays with tox-icologically relevant genes (tox genes) for evaluation of chemical toxicans in Sprague-Dawley rats in vivo and human hepatocytes in vitro
-
Kier, L. D., Neft, R., Tang, L., Suizu, R., Cook, T., Onsurez, K., Tiegler, K., Sakai, Y., Ortiz, M., Nolan, T., Sankar, U., and Li, A. P. (2004): Applications of microarrays with tox-icologically relevant genes (tox genes) for evaluation of chemical toxicans in Sprague-Dawley rats in vivo and human hepatocytes in vitro. Mutat. Res., 549:101-113.
-
(2004)
Mutat. Res
, vol.549
, pp. 101-113
-
-
Kier, L.D.1
Neft, R.2
Tang, L.3
Suizu, R.4
Cook, T.5
Onsurez, K.6
Tiegler, K.7
Sakai, Y.8
Ortiz, M.9
Nolan, T.10
Sankar, U.11
Li, A.P.12
-
187
-
-
34250127719
-
Physiological pharmacokinetic modeling of cisdichlorodiamine platinum (II) (DDP) in several species
-
King, F. G., Dedrick, R. L., and Farris, F. F. (1986): Physiological pharmacokinetic modeling of cisdichlorodiamine platinum (II) (DDP) in several species. J. Pharmacokin. Biopharmaceut., 14:131-155.
-
(1986)
J. Pharmacokin. Biopharmaceut
, vol.14
, pp. 131-155
-
-
King, F.G.1
Dedrick, R.L.2
Farris, F.F.3
-
188
-
-
21544473568
-
Evaluation of the ability of a battery of 3 in vitro genotoxicity tests to discriminate rodent carcinogens and noncarcinogens. I. Sensitivity, specificity and relative predictivity
-
Kirkland, D. J., Aardema, M., Henderson, L., and Müller, L. (2005): Evaluation of the ability of a battery of 3 in vitro genotoxicity tests to discriminate rodent carcinogens and noncarcinogens. I. Sensitivity, specificity and relative predictivity. Mutat. Res., 584:1-256.
-
(2005)
Mutat. Res
, vol.584
, pp. 1-256
-
-
Kirkland, D.J.1
Aardema, M.2
Henderson, L.3
Müller, L.4
-
189
-
-
28944451562
-
Testing strategies in mutagenicity and genetic toxicology: An appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluation of hair dyes
-
Kirkland, D. J., Henderson, L., Marzin, D., Müller, L., Parry, J. M., Speit, G., Tweats, D. J., and Williams, G. M. (2005): Testing strategies in mutagenicity and genetic toxicology: an appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluation of hair dyes. Mutat. Res., 588: 88-105.
-
(2005)
Mutat. Res
, vol.588
, pp. 88-105
-
-
Kirkland, D.J.1
Henderson, L.2
Marzin, D.3
Müller, L.4
Parry, J.M.5
Speit, G.6
Tweats, D.J.7
Williams, G.M.8
-
190
-
-
0033386217
-
The role of diet and caloric intake in aging, obesity and cancer
-
Klaassen, C. D. (1999): The role of diet and caloric intake in aging, obesity and cancer. Toxicol. Sci., 2(Suppl.): 1-146.
-
(1999)
Toxicol. Sci
, vol.2
, pp. 1-146
-
-
Klaassen, C.D.1
-
191
-
-
0346156024
-
PPAR-alpha agonist-induced rodent tumors: Modes of action and human relevance
-
Klaunig, J. E., Babich, M. A., Baetcke, K. P., Cook, J. C., Corton, J. C. et al. (2003): PPAR-alpha agonist-induced rodent tumors: modes of action and human relevance. Crit. Rev. Toxicol., 33(6):655-780.
-
(2003)
Crit. Rev. Toxicol
, vol.33
, Issue.6
, pp. 655-780
-
-
Klaunig, J.E.1
Babich, M.A.2
Baetcke, K.P.3
Cook, J.C.4
Corton, J.C.5
-
192
-
-
0028157137
-
Approaches to SAR in carcinogenesis and mutagenesis: Prediction of carcinogenicity/mutagenicity using MULTICASE
-
Klopman, G. and Rosenkranz, H. S. (1994): Approaches to SAR in carcinogenesis and mutagenesis: prediction of carcinogenicity/mutagenicity using MULTICASE. Mutat. Res., 305:33-46.
-
(1994)
Mutat. Res
, vol.305
, pp. 33-46
-
-
Klopman, G.1
Rosenkranz, H.S.2
-
193
-
-
0018804139
-
Laboratory animal feed
-
Knapka, J. J. (1979): Laboratory animal feed. Science, 204: 1367-1368.
-
(1979)
Science
, vol.204
, pp. 1367-1368
-
-
Knapka, J.J.1
-
194
-
-
3242825777
-
Pharmacokinetic experiments in animals: Needs and application of data
-
Komulainen, H. (1996): Pharmacokinetic experiments in animals: needs and application of data. Scand. J. Lab. Anim. Sci., 23:315-316.
-
(1996)
Scand. J. Lab. Anim. Sci
, vol.23
, pp. 315-316
-
-
Komulainen, H.1
-
195
-
-
0039462911
-
Statistical tests with historical controls
-
edited by H. C. Grice and J. L. Ciminera, Springer-Verlag, New York
-
Krewski, D., Smythe, R. T., Dewanji, A., and Colin, D. (1988): Statistical tests with historical controls. In: Carci-nogenicity, edited by H. C. Grice and J. L. Ciminera, pp. 23-38. Springer-Verlag, New York.
-
(1988)
Carci-nogenicity
, pp. 23-38
-
-
Krewski, D.1
Smythe, R.T.2
Dewanji, A.3
Colin, D.4
-
196
-
-
0028046398
-
Ultraviolet radiation and immunology: Something new under the sun (Presidential address)
-
Kripke, M. L. (1994): Ultraviolet radiation and immunology: something new under the sun (Presidential address). Cancer Res., 54:6102-6105.
-
(1994)
Cancer Res
, vol.54
, pp. 6102-6105
-
-
Kripke, M.L.1
-
197
-
-
0022970225
-
Forestomach carcinogens: Possible mechanisms of action
-
Kroes, R. and Wester, P. W. (1986): Forestomach carcinogens: possible mechanisms of action. Food Chem. Toxicol., 24:1083-1089.
-
(1986)
Food Chem. Toxicol
, vol.24
, pp. 1083-1089
-
-
Kroes, R.1
Wester, P.W.2
-
198
-
-
10744227159
-
Structure-based thresholds of toxicological concern (TTC): Guidance for application to substances present at low levels in the diet
-
Kroes, R., Renwick, A. G., Cheeseman, M., Kleiner, J., Mangelsdorf, I., Piersma, A., Schilter, B., Schlatter, J., van Schothorst, F., Vos, J. G., and Wurtzen, G. (2004): Structure-based thresholds of toxicological concern (TTC): guidance for application to substances present at low levels in the diet. Food Chem. Toxicol., 42(1):65-83.
-
(2004)
Food Chem. Toxicol
, vol.42
, Issue.1
, pp. 65-83
-
-
Kroes, R.1
Renwick, A.G.2
Cheeseman, M.3
Kleiner, J.4
Mangelsdorf, I.5
Piersma, A.6
Schilter, B.7
Schlatter, J.8
van Schothorst, F.9
Vos, J.G.10
Wurtzen, G.11
-
199
-
-
0002924598
-
Tumors of the urinary bladder
-
Tumors of the Rat, IARC Publ. No. 99. International Agency for Research on Cancer, Lyon, France
-
Kunze, E. and Chowaniec, J. (1990): Tumors of the urinary bladder. In: Pathology of Tumours in Laboratory Animals. Vol. I. Tumors of the Rat, IARC Publ. No. 99, pp. 345-373. International Agency for Research on Cancer, Lyon, France.
-
(1990)
Pathology of Tumours in Laboratory Animals
, vol.1
, pp. 345-373
-
-
Kunze, E.1
Chowaniec, J.2
-
200
-
-
0017892743
-
Age related and light associated retinal changes in Fischer rats
-
Lai, Y. L., Jacoby, R., and Jonas, A. (1978): Age related and light associated retinal changes in Fischer rats. Invest. Ophthalmol. Vis. Sci., 17:634-638.
-
(1978)
Invest. Ophthalmol. Vis. Sci
, vol.17
, pp. 634-638
-
-
Lai, Y.L.1
Jacoby, R.2
Jonas, A.3
-
201
-
-
0016684982
-
Carcinogenicity of 6-aminochrysene in mice
-
Lavbelin, G., Roba, J., Roncucci, R., and Parmentier, R. (1975): Carcinogenicity of 6-aminochrysene in mice. Eur. J. Cancer, 11:327-334.
-
(1975)
Eur. J. Cancer
, vol.11
, pp. 327-334
-
-
Lavbelin, G.1
Roba, J.2
Roncucci, R.3
Parmentier, R.4
-
202
-
-
0030596897
-
The pH 6.7 Syrian hamster embryo cell transformation assay for assessing the carcinogenic potential of chemicals
-
Le Boeuf, R. A., Kerckaert, G. Aardema, M., Gibson, D., Brauninger, R., and Isfort, R. (1996): The pH 6.7 Syrian hamster embryo cell transformation assay for assessing the carcinogenic potential of chemicals. Mutat. Res., 356: 85-127.
-
(1996)
Mutat. Res
, vol.356
, pp. 85-127
-
-
le Boeuf, R.A.1
Kerckaert, G.2
Aardema, M.3
Gibson, D.4
Brauninger, R.5
Isfort, R.6
-
203
-
-
0025647881
-
V-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: Effects of phorbol esters and retinoic acid
-
Leder, A., Kuo, A., Cardiff, R. D., Sinn, E., and Leder, P. (1990): v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid. Proc. Natl. Acad. Sci. U.S.A., 87:9178-9182.
-
(1990)
Proc. Natl. Acad. Sci. U.S.A
, vol.87
, pp. 9178-9182
-
-
Leder, A.1
Kuo, A.2
Cardiff, R.D.3
Sinn, E.4
Leder, P.5
-
204
-
-
15444356125
-
Assumptions in analyses of the bioassay: A statistician's view
-
edited by H. C. Grice and J. L Ciminera, Springer-Verlag, New York
-
Lee, P. (1988): Assumptions in analyses of the bioassay: a statistician's view. In: Carcinogenicity, edited by H. C. Grice and J. L Ciminera, pp. 1-10. Springer-Verlag, New York.
-
(1988)
Carcinogenicity
, pp. 1-10
-
-
Lee, P.1
-
205
-
-
0001877579
-
Ten-fold safety factor studies
-
Lehman, A. J. and Fitshugh, O. G. (1954): Ten-fold safety factor studies. U.S. Q. Bull., XVIII (1):33-35.
-
(1954)
U.S. Q. Bull
, vol.18
, Issue.1
, pp. 33-35
-
-
Lehman, A.J.1
Fitshugh, O.G.2
-
206
-
-
0023688163
-
Application of pharmacokinetic to derive biological exposure indexes from threshold limit values
-
Leung, H. W. and Paustenbach, D. J. (1988): Application of pharmacokinetic to derive biological exposure indexes from threshold limit values. Am. Indust. Hyg. Assoc., 49: 445-450.
-
(1988)
Am. Indust. Hyg. Assoc
, vol.49
, pp. 445-450
-
-
Leung, H.W.1
Paustenbach, D.J.2
-
207
-
-
26844508008
-
Chronic toxicity and carcinogenic evaluation of diisonoyl phthalate in rats
-
Lington, A. W., Bird, M. G., Plutnick, R. T., Stubblefield, W. A., and Scala, R. A. (1997): Chronic toxicity and carcinogenic evaluation of diisonoyl phthalate in rats. Fundam. Appl. Toxicol., 36:79-89.
-
(1997)
Fundam. Appl. Toxicol
, vol.36
, pp. 79-89
-
-
Lington, A.W.1
Bird, M.G.2
Plutnick, R.T.3
Stubblefield, W.A.4
Scala, R.A.5
-
208
-
-
0031955222
-
Precision in data acquisition and reporting of organ weights in rats and mice
-
Long, G. G., Symanowski, J. T., and Roback, K. (1998): Precision in data acquisition and reporting of organ weights in rats and mice. Toxicol. Pathol., 26:316-318.
-
(1998)
Toxicol. Pathol
, vol.26
, pp. 316-318
-
-
Long, G.G.1
Symanowski, J.T.2
Roback, K.3
-
209
-
-
0022490893
-
Quantitative evaluation of DNA binding data for risk estimation and for classification of direct and indirect carcinogens
-
Lutz, W. K. (1986): Quantitative evaluation of DNA binding data for risk estimation and for classification of direct and indirect carcinogens. J. Cancer Res. Clin. Oncol., 112: 85-91.
-
(1986)
J. Cancer Res. Clin. Oncol
, vol.112
, pp. 85-91
-
-
Lutz, W.K.1
-
210
-
-
10744226756
-
The utility of genetically modified mouse assays for identifying human carcinogens: A basic understanding and path forward
-
MacDonald, J., French, J. E., Gerson, R. J., Goodman, J., Inoue, T. et al. (2004): The utility of genetically modified mouse assays for identifying human carcinogens: a basic understanding and path forward. Toxicol. Sci., 77:188-194.
-
(2004)
Toxicol. Sci
, vol.77
, pp. 188-194
-
-
MacDonald, J.1
French, J.E.2
Gerson, R.J.3
Goodman, J.4
Inoue, T.5
-
211
-
-
8444243683
-
Human carcinogenic risk evaluation. Part IV. Assessment of human risk of cancer from chemical exposure using a global weight-of-evidence approach
-
MacDonald, J. S. (2004): Human carcinogenic risk evaluation. Part IV. Assessment of human risk of cancer from chemical exposure using a global weight-of-evidence approach. Toxicol. Sci., 82:3-8.
-
(2004)
Toxicol. Sci
, vol.82
, pp. 3-8
-
-
MacDonald, J.S.1
-
212
-
-
0030463716
-
Spontaneous lesions in aging FVB/N mice
-
Mahler, J. F., Stokes, W., Mann, P. C., Takaoka, M., and Maronpot, R. R. (1996): Spontaneous lesions in aging FVB/N mice. Toxicol. Pathol., 24:710-716.
-
(1996)
Toxicol. Pathol
, vol.24
, pp. 710-716
-
-
Mahler, J.F.1
Stokes, W.2
Mann, P.C.3
Takaoka, M.4
Maronpot, R.R.5
-
213
-
-
0031824685
-
Spontaneous and chemically-induced proliferative lesions in Tg.AC transgenic and p53-heterozygous mice
-
Mahler, J. P., Flagler, N. D., Malarkey, D. E., Mann, P. C., Haseman, J. K., and Eastin, W. (1998): Spontaneous and chemically-induced proliferative lesions in Tg.AC transgenic and p53-heterozygous mice. Toxicol. Pathol., 26: 501-511.
-
(1998)
Toxicol. Pathol
, vol.26
, pp. 501-511
-
-
Mahler, J.P.1
Flagler, N.D.2
Malarkey, D.E.3
Mann, P.C.4
Haseman, J.K.5
Eastin, W.6
-
214
-
-
0023696954
-
Mortality, major cause of moribundity, and spontaneous tumors in CD-1 mice
-
Maita, K., Hirano, M., Harada, T., Mitsumori., K., Yoshida, A., Takahashi, K., Nakashima, N., Kitazawa, T., Enomoto, A., Inui, K., and Shirasu, Y. (1988): Mortality, major cause of moribundity, and spontaneous tumors in CD-1 mice. Toxicol. Pathol., 16:340-349.
-
(1988)
Toxicol. Pathol
, vol.16
, pp. 340-349
-
-
Maita, K.1
Hirano, M.2
Harada, T.3
Mitsumori, K.4
Yoshida, A.5
Takahashi, K.6
Nakashima, N.7
Kitazawa, T.8
Enomoto, A.9
Inui, K.10
Shirasu, Y.11
-
215
-
-
26944458889
-
-/-, and wild-type mice during 9 months' dietary exposure
-
-/-, and wild-type mice during 9 months' dietary exposure. Toxicol. Pathol., 33:609-620.
-
(2005)
Toxicol. Pathol
, vol.33
, pp. 609-620
-
-
McAnulty, P.A.1
Skydsgaard, M.2
-
216
-
-
85132682243
-
Generation, characterization and exposure systems for test atmospheres
-
edited by W. E. Lloyd. Hemisphere, Washington, D.C
-
McClellan, R. O. and Hobbs, C. H. (1986): Generation, characterization and exposure systems for test atmospheres. In: Safety Evaluation of Chemicals, edited by W. E. Lloyd. Hemisphere, Washington, D.C.
-
(1986)
Safety Evaluation of Chemicals
-
-
McClellan, R.O.1
Hobbs, C.H.2
-
217
-
-
0020962625
-
Pathology requirements for rodent two year studies. I. A review of current procedures
-
McConnell, E. E. (1983): Pathology requirements for rodent two year studies. I. A review of current procedures. Toxicol. Pathol., 11:60-64.
-
(1983)
Toxicol. Pathol
, vol.11
, pp. 60-64
-
-
McConnell, E.E.1
-
218
-
-
0022573516
-
Guidelines of combining neoplasms for evaluation of rodent carcinogenesis studies
-
McConnell, E. E., Solleveld, H. A., Swenberg, J. A., and Boorman, G. A. (1986): Guidelines of combining neoplasms for evaluation of rodent carcinogenesis studies. J. Natl. Cancer Res., 76:283-289.
-
(1986)
J. Natl. Cancer Res
, vol.76
, pp. 283-289
-
-
McConnell, E.E.1
Solleveld, H.A.2
Swenberg, J.A.3
Boorman, G.A.4
-
219
-
-
0344381837
-
General observations on the effects of sex steroids in rodents with emphasis on longterm oral contraceptive studies
-
edited by F. Michael, Cambridge University Press, New York
-
McConnell, R. F. (1989): General observations on the effects of sex steroids in rodents with emphasis on longterm oral contraceptive studies. In: Safety Requirements for Contraceptive Steroids, edited by F. Michael, pp. 211-229. Cambridge University Press, New York.
-
(1989)
Safety Requirements for Contraceptive Steroids
, pp. 211-229
-
-
McConnell, R.F.1
-
220
-
-
0013549395
-
Proliferative lesions of the testes in rats with selected examples from mice
-
STP/ARP/AFIP, Washington, D.C
-
McConnell, R. F., Westen, H. H., Ulland, B. M., Bosland, M. C., and Ward, J. M. (1992): Proliferative lesions of the testes in rats with selected examples from mice. In: Guides for Toxicologic Pathology. STP/ARP/AFIP, Washington, D.C.
-
(1992)
Guides for Toxicologic Pathology
-
-
McConnell, R.F.1
Westen, H.H.2
Ulland, B.M.3
Bosland, M.C.4
Ward, J.M.5
-
221
-
-
0026677389
-
Neoplasms and related proliferative lesions in control Sprague-Dawley rats from carcinogenicity studies: Historical data and diagnostic considerations
-
McMartin, D. N. Sahota, P. S., Gunson, D. E., Hsu, H. H., and Spaet, R. H. (1992): Neoplasms and related proliferative lesions in control Sprague-Dawley rats from carcinogenicity studies: historical data and diagnostic considerations. Toxicol. Pathol., 20:212-225.
-
(1992)
Toxicol. Pathol
, vol.20
, pp. 212-225
-
-
McMartin, D.N.1
Sahota, P.S.2
Gunson, D.E.3
Hsu, H.H.4
Spaet, R.H.5
-
222
-
-
0023198607
-
The hepatocytes primary culture/DNA repair test using hepatocytes from several species
-
McQueen, C. A. and Williams, G. M. (1987): The hepatocytes primary culture/DNA repair test using hepatocytes from several species. Cell Biol. Toxicol., 3:209-218.
-
(1987)
Cell Biol. Toxicol
, vol.3
, pp. 209-218
-
-
McQueen, C.A.1
Williams, G.M.2
-
223
-
-
0024212670
-
Genotoxicity of carcinogens in human hepatocytes: Application in hazard assessment
-
McQueen, C. A. and Williams, G. M. (1988): Genotoxicity of carcinogens in human hepatocytes: application in hazard assessment. Toxicol. Appl. Pharmacol., 96:360-366.
-
(1988)
Toxicol. Appl. Pharmacol
, vol.96
, pp. 360-366
-
-
McQueen, C.A.1
Williams, G.M.2
-
227
-
-
14644396096
-
Nanomedicine: Current status and future prospects
-
Moghimi, S. M., Hunter, A. C., and Murray, J. C. (2005): Nanomedicine: current status and future prospects. FASEB J., 19:311-330.
-
(2005)
FASEB J
, vol.19
, pp. 311-330
-
-
Moghimi, S.M.1
Hunter, A.C.2
Murray, J.C.3
-
228
-
-
0026521626
-
What is an appropriate measure of exposure when testing drugs for carcinogenicity in rodents?
-
Monro, A. (1992): What is an appropriate measure of exposure when testing drugs for carcinogenicity in rodents? Toxicol. Appl. Pharmacol., 112:171-181.
-
(1992)
Toxicol. Appl. Pharmacol
, vol.112
, pp. 171-181
-
-
Monro, A.1
-
229
-
-
0027190411
-
How useful are chronic (life-span) toxicology studies in rodents in identifying pharmaceuticals that pose a carcinogenic risk to humans?
-
Monro, A. (1993): How useful are chronic (life-span) toxicology studies in rodents in identifying pharmaceuticals that pose a carcinogenic risk to humans? Adv. Drug React. Toxicol. Rev., 12:5-34.
-
(1993)
Adv. Drug React. Toxicol. Rev
, vol.12
, pp. 5-34
-
-
Monro, A.1
-
230
-
-
0030005665
-
Are lifespan rodent carcinogenicity studies defensible for pharmaceutical agents?
-
Monro, A. (1996): Are lifespan rodent carcinogenicity studies defensible for pharmaceutical agents? Exp. Toxicol. Pathol., 48:155-166.
-
(1996)
Exp. Toxicol. Pathol
, vol.48
, pp. 155-166
-
-
Monro, A.1
-
231
-
-
0028178048
-
A preliminary evaluation of the performance of the Muta Mouse (bac Z) and Big Blue (bac I) transgenic mouse mutation assays
-
Morrison, V. and Ashby, J. (1994): A preliminary evaluation of the performance of the Muta Mouse (bac Z) and Big Blue (bac I) transgenic mouse mutation assays. Mutagenesis, 9:367-376.
-
(1994)
Mutagenesis
, vol.9
, pp. 367-376
-
-
Morrison, V.1
Ashby, J.2
-
232
-
-
0031948975
-
Sex-dependent metabolism of xenobiotics
-
Mugford, C. A. and Kedderis, G. L. (1998): Sex-dependent metabolism of xenobiotics. Drug Metab. Rev., 30(3): 441-498.
-
(1998)
Drug Metab. Rev
, vol.30
, Issue.3
, pp. 441-498
-
-
Mugford, C.A.1
Kedderis, G.L.2
-
233
-
-
0022620186
-
Sex differences in drug conjugation and their consequences for drug toxicity: Sulfation, glucu-ronidation and glutathione conjugation
-
Mulder, G. J. (1986): Sex differences in drug conjugation and their consequences for drug toxicity: sulfation, glucu-ronidation and glutathione conjugation. Chem. Biol. Interact., 57:1-15.
-
(1986)
Chem. Biol. Interact
, vol.57
, pp. 1-15
-
-
Mulder, G.J.1
-
234
-
-
0017551380
-
Considerations in chronic testing: The chemical, the dose, the design
-
Munro, I. C. (1977): Considerations in chronic testing: the chemical, the dose, the design. J. Environ. Pathol. Toxicol., 1:183-197.
-
(1977)
J. Environ. Pathol. Toxicol
, vol.1
, pp. 183-197
-
-
Munro, I.C.1
-
235
-
-
0029974283
-
Thresholds of toxicological concern based on structure-activity relationships
-
Munro, I. C., Ford, R. A., Kennepohl, E., and Sprenger, J. G. (1996): Thresholds of toxicological concern based on structure-activity relationships. Drug Metab. Rev., 28: 209-217.
-
(1996)
Drug Metab. Rev
, vol.28
, pp. 209-217
-
-
Munro, I.C.1
Ford, R.A.2
Kennepohl, E.3
Sprenger, J.G.4
-
238
-
-
85132683750
-
-
NIH Publ. 86-23. National Institutes of Health, Washington, D.C
-
NIH. (1986): Humane Care and Use of Laboratory Animals, NIH Publ. 86-23. National Institutes of Health, Washington, D.C.
-
(1986)
Humane Care and Use of Laboratory Animals
-
-
-
242
-
-
85149232555
-
-
NTP Tech. Rep. 460, NIH Publ. No. 97-3376. National Toxicology Program, Research Triangle Park, NC
-
1 Mice, NTP Tech. Rep. 460, NIH Publ. No. 97-3376, pp. 1-411. National Toxicology Program, Research Triangle Park, NC.
-
(1997)
1 Mice
, pp. 1-411
-
-
-
244
-
-
85132687034
-
-
National Toxicology Program, Research Triangle Park, NC
-
NTP. (2005): NTP Technical Reports Index. National Toxicology Program, Research Triangle Park, NC.
-
(2005)
NTP Technical Reports Index
-
-
-
245
-
-
9044254525
-
P450 superfamily: Update on new sequences, gene mapping accession numbers and nomenclature
-
Nelson, D. R., Koymans, L., Kamatski, T., Stegeman, J. J., Feyereisen, R. et al. (1996): P450 superfamily: update on new sequences, gene mapping accession numbers and nomenclature. Pharmacogenetics, 6:1-42.
-
(1996)
Pharmacogenetics
, vol.6
, pp. 1-42
-
-
Nelson, D.R.1
Koymans, L.2
Kamatski, T.3
Stegeman, J.J.4
Feyereisen, R.5
-
246
-
-
0022489445
-
The role of DNA damage in chemical carcinogenesis of aromatic amines
-
Neumann, H.-G. (1986); The role of DNA damage in chemical carcinogenesis of aromatic amines. J. Cancer Res. Clin. Oncol., 112:100-106.
-
(1986)
J. Cancer Res. Clin. Oncol
, vol.112
, pp. 100-106
-
-
Neumann, H.-G.1
-
247
-
-
1342315260
-
Philosophy of blind slide reading in toxicologic pathology
-
Newberne, P. M. and de la Iglesia, F. A. (1985): Philosophy of blind slide reading in toxicologic pathology. Toxicol. Pathol., 13:225.
-
(1985)
Toxicol. Pathol
, vol.13
, pp. 225
-
-
Newberne, P.M.1
de la Iglesia, F.A.2
-
248
-
-
0030479494
-
Diet: The neglected variable in chemical safety evaluations
-
Newberne, P. M. and Sotnikov, A. V. (1996): Diet: the neglected variable in chemical safety evaluations. Toxicol. Pathol., 24:746-756.
-
(1996)
Toxicol. Pathol
, vol.24
, pp. 746-756
-
-
Newberne, P.M.1
Sotnikov, A.V.2
-
249
-
-
20444499704
-
The presence of drug in control samples during toxicokinetic investigations: A Novartis perspective
-
Nicholls, I., Kolopp, M., Pommier, F., and Scheiwiller, M. (2005): The presence of drug in control samples during toxicokinetic investigations: a Novartis perspective. Reg. Toxicol. Pharmacol., 42:172-178.
-
(2005)
Reg. Toxicol. Pharmacol
, vol.42
, pp. 172-178
-
-
Nicholls, I.1
Kolopp, M.2
Pommier, F.3
Scheiwiller, M.4
-
250
-
-
85132683761
-
Automated data acquisition systems in the 80s and beyond. II. Operation
-
edited by A. Tegeris, Karger, New York
-
Noble, J. F. (1984): Automated data acquisition systems in the 80s and beyond. II. Operation. In: Toxicology Laboratory Design and Management for the 80s and Beyond, edited by A. Tegeris, pp. 143-158. Karger, New York.
-
(1984)
Toxicology Laboratory Design and Management for the 80s and Beyond
, pp. 143-158
-
-
Noble, J.F.1
-
251
-
-
20644449754
-
Nanotoxicology: An emerging discipline evolving from studies of ultrafine particles
-
Oberdörster, G., Oberdörster, E., and Oberdörster, J. (2005): Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ. Health Perspect, 113:823-839.
-
(2005)
Environ. Health Perspect
, vol.113
, pp. 823-839
-
-
Oberdörster, G.1
Oberdörster, E.2
Oberdörster, J.3
-
252
-
-
0000935601
-
Chemical carcinogens: A review of the science and its associated principles
-
Office of Science and Technology Policy. (1985): Chemical carcinogens: a review of the science and its associated principles. Fed. Reg., 50(184):10371-10442.
-
(1985)
Fed. Reg
, vol.50
, Issue.184
, pp. 10371-10442
-
-
-
254
-
-
0028843173
-
Antiepileptic treatment and risk for hepatobiliary cancer and malignant lymphoma
-
Olsen, J. H., Schulgen, G., Boice, J. D., Whysner, J., Travis, L. B., Williams, G. M., Johnson, F. B., and O'McGee, J. (1995): Antiepileptic treatment and risk for hepatobiliary cancer and malignant lymphoma. Cancer Res., 55:294-297.
-
(1995)
Cancer Res
, vol.55
, pp. 294-297
-
-
Olsen, J.H.1
Schulgen, G.2
Boice, J.D.3
Whysner, J.4
Travis, L.B.5
Williams, G.M.6
Johnson, F.B.7
O'McGee, J.8
-
255
-
-
0343902519
-
A comparative study of the effects of embedding cellophane and polystyrene films in rats
-
Oppenheimer, E. T., Willhite, M., Stout, A. F., Damishofsky, I., and Fishman, M. M. (1964): A comparative study of the effects of embedding cellophane and polystyrene films in rats. Cancer Res, 24:379-386.
-
(1964)
Cancer Res
, vol.24
, pp. 379-386
-
-
Oppenheimer, E.T.1
Willhite, M.2
Stout, A.F.3
Damishofsky, I.4
Fishman, M.M.5
-
256
-
-
85132684922
-
Adopted Guidelines for Testing of Chemicals. Section 4
-
No. 451, Carcinogenicity Studies. Organization of Economic Cooperation and Development, Paris, France
-
OECD. (1981): Adopted Guidelines for Testing of Chemicals. Section 4. Health Effects, No. 451, Carcinogenicity Studies. Organization of Economic Cooperation and Development, Paris, France.
-
(1981)
Health Effects
-
-
-
257
-
-
0003642838
-
-
ENV/mc/CHEM(98)17. Organization of Economic Cooperation and Development, Paris, France
-
OECD. (OECD) (1998): Principles of Good Laboratory Practices, ENV/mc/CHEM(98)17. Organization of Economic Cooperation and Development, Paris, France.
-
(1998)
Principles of Good Laboratory Practices
-
-
-
258
-
-
15044350441
-
Susceptibilities of p53 knockout and rasH2 transgenic mice to urethane-induced lung carcinogenesis are inherited from their original strains
-
Ozaki, M., Ozaki, K., Watanabe, T., Uwagawa, S., Okuno, Y., and Shirai, T. (2005): Susceptibilities of p53 knockout and rasH2 transgenic mice to urethane-induced lung carcinogenesis are inherited from their original strains. Toxicol. Pathol, 33:267-271.
-
(2005)
Toxicol. Pathol
, vol.33
, pp. 267-271
-
-
Ozaki, M.1
Ozaki, K.2
Watanabe, T.3
Uwagawa, S.4
Okuno, Y.5
Shirai, T.6
-
259
-
-
0000106986
-
Biotransformation of Xenobiotics
-
6th ed., edited by C. D. Klaassen, McGraw-Hill, New York
-
Parkinson, A. (2001): Biotransformation of Xenobiotics. In: Casarett & Doull's Toxicology, 6th ed., edited by C. D. Klaassen, pp. 133-224. McGraw-Hill, New York.
-
(2001)
Casarett & Doull's Toxicology
, pp. 133-224
-
-
Parkinson, A.1
-
260
-
-
0026744688
-
Opportunities for integration of pharmacokinetics, pharmacody-namics and toxicokinetics in rational drug design
-
Peck, C. C., Barr, W. H., and Benet, L. Z. (1992): Opportunities for integration of pharmacokinetics, pharmacody-namics and toxicokinetics in rational drug design. J. Pharmaceut. Sci, 81:605-610.
-
(1992)
J. Pharmaceut. Sci
, vol.81
, pp. 605-610
-
-
Peck, C.C.1
Barr, W.H.2
Benet, L.Z.3
-
261
-
-
0032102436
-
Effect of rodent hepatocarcinogenic peroxisome prolifer-ators on fatty acyl-CoA oxidase, DNA synthesis, and apo-ptosis in cultured human and rat hepatocytes
-
Perrone, C. E., Shao, L., and Williams, G. M. (1998): Effect of rodent hepatocarcinogenic peroxisome prolifer-ators on fatty acyl-CoA oxidase, DNA synthesis, and apo-ptosis in cultured human and rat hepatocytes. Toxicol. Appl. Pharmacol., 150:277-286.
-
(1998)
Toxicol. Appl. Pharmacol
, vol.150
, pp. 277-286
-
-
Perrone, C.E.1
Shao, L.2
Williams, G.M.3
-
262
-
-
9744227270
-
Embryonic turkey liver: Activities of biotransformation enzymes and cultivation of DNA-reactive carcinogens
-
Perrone, C., Ahr, H.-J., Duan, J. D., Jeffrey, A. M., Schmidt, U., Williams, G. M., and Enzmann, H. G. (2004): Embryonic turkey liver: activities of biotransformation enzymes and cultivation of DNA-reactive carcinogens. Arch. Toxicol., 78:589-598.
-
(2004)
Arch. Toxicol
, vol.78
, pp. 589-598
-
-
Perrone, C.1
Ahr, H.-J.2
Duan, J.D.3
Jeffrey, A.M.4
Schmidt, U.5
Williams, G.M.6
Enzmann, H.G.7
-
263
-
-
0019291735
-
Guidelines for simple, sensitive significance tests for carcinogenic effects in long-term animal experiments
-
edited by R. Montesano, H. Bartsch, and L. Tomatis, IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Suppl. 2, International Agency for Research on Cancer, Lyon, France
-
Peto, R., Pike, M. C., Day, N. E., Gray, R. G., Lee, P. N., Parish, S., Peto, J., and Wahrendorf, J. (1980): Guidelines for simple, sensitive significance tests for carcinogenic effects in long-term animal experiments. In: Long-Term and Short-Term Screening Assays for Carcinogens: A Critical Appraisal, edited by R. Montesano, H. Bartsch, and L. Tomatis, IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Suppl. 2, pp. 311-426. International Agency for Research on Cancer, Lyon, France.
-
(1980)
Long-Term and Short-Term Screening Assays for Carcinogens: A Critical Appraisal
, pp. 311-426
-
-
Peto, R.1
Pike, M.C.2
Day, N.E.3
Gray, R.G.4
Lee, P.N.5
Parish, S.6
Peto, J.7
Wahrendorf, J.8
-
264
-
-
0021647476
-
A proposed general convention for the numerical description of carcinogenic potency of chemicals in chronic-exposures animal experiments
-
Peto, R., Pike, M. C., Bernstein, L., Gold, L. S., and Ames, B. N. (1984): A proposed general convention for the numerical description of carcinogenic potency of chemicals in chronic-exposures animal experiments. Environ. Health Perspect, 58:1-8.
-
(1984)
Environ. Health Perspect
, vol.58
, pp. 1-8
-
-
Peto, R.1
Pike, M.C.2
Bernstein, L.3
Gold, L.S.4
Ames, B.N.5
-
265
-
-
0030747224
-
32P-postlabeling assay
-
32P-postlabeling assay. Mutat. Res., 378(102):1-12.
-
(1997)
Mutat. Res
, vol.378
, Issue.102
, pp. 1-12
-
-
Phillips, D.H.1
-
266
-
-
85132686808
-
Bone marrow metabolism
-
Recombinant human insulin (Lantus), Tamoxifen, 2966 edited by L. Murray. Thompson PDR, Montvale, NJ
-
PDR. (2005): Bone marrow metabolism, pp. 1840-1844; Recombinant human insulin (Lantus), pp. 715-719; Tamoxifen, pp. 622, 2966. In: Physician's Desk Reference, edited by L. Murray. Thompson PDR, Montvale, NJ.
-
(2005)
Physician's Desk Reference
-
-
-
267
-
-
0031753238
-
Spontaneous neoplasms in control Wistar rats: A comparison of reviews
-
Poteracki, J. and Walsh, K. M. (1998): Spontaneous neoplasms in control Wistar rats: a comparison of reviews. Toxicol. Sci., 45:1-8.
-
(1998)
Toxicol. Sci
, vol.45
, pp. 1-8
-
-
Poteracki, J.1
Walsh, K.M.2
-
268
-
-
4544380265
-
Development of hiber-nomas in rats dosed with phentolamine mesylate during the 24-month carcinogenicity study
-
Poulet, F. M., Berardi, M. R., Halliwell, W., Hartman, B., Auletta, C., and Bolte, H. (2004): Development of hiber-nomas in rats dosed with phentolamine mesylate during the 24-month carcinogenicity study. Toxicol. Pathol., 32(5):558-566.
-
(2004)
Toxicol. Pathol
, vol.32
, Issue.5
, pp. 558-566
-
-
Poulet, F.M.1
Berardi, M.R.2
Halliwell, W.3
Hartman, B.4
Auletta, C.5
Bolte, H.6
-
269
-
-
3242826607
-
Interpretation of data from toxicokinetic studies
-
Powles, P. (1996): Interpretation of data from toxicokinetic studies. Scand. J. Lab. Anim. Sci., 23:317-323.
-
(1996)
Scand. J. Lab. Anim. Sci
, vol.23
, pp. 317-323
-
-
Powles, P.1
-
270
-
-
0028213793
-
Leydig cell hyperplasia and adenomas in mice treated with finasteride, a 5α-reductase inhibitor: Possible mechanism
-
Prahalada, S., Majka, J. A., Soper, K. A., Nett, T. M., Bagdon, W. J., Peter, C. P., Burek, J. D., MacDonald, J. S., and van Zwieten, M. J. (1994): Leydig cell hyperplasia and adenomas in mice treated with finasteride, a 5α-reductase inhibitor: possible mechanism. Fundam. Appl. Toxicol., 22: 211-219.
-
(1994)
Fundam. Appl. Toxicol
, vol.22
, pp. 211-219
-
-
Prahalada, S.1
Majka, J.A.2
Soper, K.A.3
Nett, T.M.4
Bagdon, W.J.5
Peter, C.P.6
Burek, J.D.7
MacDonald, J.S.8
van Zwieten, M.J.9
-
272
-
-
0023249622
-
Influence of body weight on the incidence of spontaneous tumors in rats and mice of long-term studies
-
Rao, G. N., Piegorsch, W. W., and Haseman, J. K. (1987): Influence of body weight on the incidence of spontaneous tumors in rats and mice of long-term studies. Am. J. Clin. Nutr., 45:252-260.
-
(1987)
Am. J. Clin. Nutr
, vol.45
, pp. 252-260
-
-
Rao, G.N.1
Piegorsch, W.W.2
Haseman, J.K.3
-
274
-
-
0033372833
-
Optimization of carcinogenicity bioassays
-
Registry of Industrial Toxicology Animal Data (RITA). (1999): Optimization of carcinogenicity bioassays. Exp. Toxicol. Pathol., 51:461-475.
-
(1999)
Exp. Toxicol. Pathol
, vol.51
, pp. 461-475
-
-
-
275
-
-
0017404537
-
The effect of continuous light exposure on the retina in albino and pigmented rats
-
Reuter, J. and Hobbelen, H. (1977): The effect of continuous light exposure on the retina in albino and pigmented rats. Physiol. Behav., 18:939-944.
-
(1977)
Physiol. Behav
, vol.18
, pp. 939-944
-
-
Reuter, J.1
Hobbelen, H.2
-
276
-
-
0019747917
-
Pathology of gestational chorio-carcinoma induced in patas monkeys by ethylnitrosourea given during pregnancy
-
Rice, J. M., Williams, G. M., Palmer, A. E., London, W. T., and Sly, D. L. (1981): Pathology of gestational chorio-carcinoma induced in patas monkeys by ethylnitrosourea given during pregnancy. Placenta, 3(Suppl.):223-230.
-
(1981)
Placenta
, vol.3
, pp. 223-230
-
-
Rice, J.M.1
Williams, G.M.2
Palmer, A.E.3
London, W.T.4
Sly, D.L.5
-
277
-
-
0033035565
-
Rodent tumors of urinary bladder, renal cortex, and thyroid gland in IARC monographs evaluation of carcinogenic risk to humans
-
Rice, J. M., Baan, R. A., Blettner, M., Genevois-Char-neau, C., Grosse, Y., McGregor, D. B., Partensky, C., and Wilbourn, J. D. (1999): Rodent tumors of urinary bladder, renal cortex, and thyroid gland in IARC monographs evaluation of carcinogenic risk to humans. Toxicol. Sci., 49:166-171.
-
(1999)
Toxicol. Sci
, vol.49
, pp. 166-171
-
-
Rice, J.M.1
Baan, R.A.2
Blettner, M.3
Genevois-Char-neau, C.4
Grosse, Y.5
McGregor, D.B.6
Partensky, C.7
Wilbourn, J.D.8
-
278
-
-
0016784535
-
Mouse mammary tumors: Alteration of incidence as apparent function of stress
-
Riley, V. (1975): Mouse mammary tumors: alteration of incidence as apparent function of stress. Science, 189: 465-467.
-
(1975)
Science
, vol.189
, pp. 465-467
-
-
Riley, V.1
-
279
-
-
0019797417
-
Psychoneuroendocrine influences on immune-competence and neoplasia
-
Riley, V. (1981): Psychoneuroendocrine influences on immune-competence and neoplasia. Science, 212: 1100-1109.
-
(1981)
Science
, vol.212
, pp. 1100-1109
-
-
Riley, V.1
-
280
-
-
4243207144
-
Principles of testing for carcinogenicity
-
3rd ed., edited by A. W. Hayes, Raven Press, New York
-
Robens, J. F., Calabrese, E. J., Piegorsch, W. W., Schueler, R. L., and Hayes, A. W. (1994): Principles of testing for carcinogenicity. In: Principles and Methods of Toxicology, 3rd ed., edited by A. W. Hayes, pp. 697-728. Raven Press, New York.
-
(1994)
Principles and Methods of Toxicology
, pp. 697-728
-
-
Robens, J.F.1
Calabrese, E.J.2
Piegorsch, W.W.3
Schueler, R.L.4
Hayes, A.W.5
-
281
-
-
0002643308
-
Breast
-
Mosby, St. Louis, MO
-
Rosai, J. (1981): Breast. In: Ackerman's Surgical Pathology, pp. 1098-1149. Mosby, St. Louis, MO.
-
(1981)
Ackerman's Surgical Pathology
, pp. 1098-1149
-
-
Rosai, J.1
-
282
-
-
0025622779
-
Tumours of the mammary gland
-
edited by V. S. Turusov and U. Mohr, IARC Publ. No. 99. International Agency for Research on Cancer, Lyon, France
-
Russo, J., Russo, I. H., Rogers, A. E., Van Zwieten, M. J., and Gusterson, B. (1990): Tumours of the mammary gland. In: Pathology of Tumours in Laboratory Animals. Vol. I. Tumors of the Rat, edited by V. S. Turusov and U. Mohr, IARC Publ. No. 99, pp. 47-78. International Agency for Research on Cancer, Lyon, France.
-
(1990)
Pathology of Tumours in Laboratory Animals Tumors of the Rat
, vol.1
, pp. 47-78
-
-
Russo, J.1
Russo, I.H.2
Rogers, A.E.3
van Zwieten, M.J.4
Gusterson, B.5
-
283
-
-
0025121594
-
Most tumors in transgenic mice with human c-Ha-ras gene contained somatically activated transgenes
-
Saitoh, A., Kimura, M., Takahashi, R., Yokoyama, M., Nomura, T., Izawa, M., Sekiya, T., Nishimura, S., and Katsuki, M. (1990): Most tumors in transgenic mice with human c-Ha-ras gene contained somatically activated transgenes. Oncogene, 5:1195-1200.
-
(1990)
Oncogene
, vol.5
, pp. 1195-1200
-
-
Saitoh, A.1
Kimura, M.2
Takahashi, R.3
Yokoyama, M.4
Nomura, T.5
Izawa, M.6
Sekiya, T.7
Nishimura, S.8
Katsuki, M.9
-
284
-
-
2842532803
-
Photocarcinogenesis and consumer product testing: Technical aspects
-
Sambuco, C. P., Davies, R. E., Forbes, P. D., and Hober-man, A. M. (1991): Photocarcinogenesis and consumer product testing: technical aspects. Toxicol. Methods, 1: 75-83.
-
(1991)
Toxicol. Methods
, vol.1
, pp. 75-83
-
-
Sambuco, C.P.1
Davies, R.E.2
Forbes, P.D.3
Hober-man, A.M.4
-
285
-
-
0018230992
-
Contamination from feeding volatile test chemicals
-
Sansone, E. B. and Losikoff, A. M. (1978): Contamination from feeding volatile test chemicals. Toxicol. Appl. Pharmacol., 46:703-708.
-
(1978)
Toxicol. Appl. Pharmacol
, vol.46
, pp. 703-708
-
-
Sansone, E.B.1
Losikoff, A.M.2
-
286
-
-
0018173194
-
Penetration of protective clothing materials by 1,2-dibromo-3-chloropro-pane, ethylene dibromide, and acrylonitrile
-
Sansone, E. B. and Tewari, Y. B. (1978): Penetration of protective clothing materials by 1,2-dibromo-3-chloropro-pane, ethylene dibromide, and acrylonitrile. J. Am. Indust. Hyg. Assoc., 39:921-922.
-
(1978)
J. Am. Indust. Hyg. Assoc
, vol.39
, pp. 921-922
-
-
Sansone, E.B.1
Tewari, Y.B.2
-
287
-
-
0017877673
-
The permeability of laboratory gloves to selected solvents
-
Sansone, E. B. and Tewari, Y. B. (1978): The permeability of laboratory gloves to selected solvents. J. Am. Indust. Hyg. Assoc., 39:169-174.
-
(1978)
J. Am. Indust. Hyg. Assoc
, vol.39
, pp. 169-174
-
-
Sansone, E.B.1
Tewari, Y.B.2
-
288
-
-
0031659636
-
Granular cell foci of the uterus in Donryu rats
-
Sasahara, K., Ando-Lu, J., Nishiyama, K., Takahashi, M., Yoshida, M., and Maekawa, A. (1998): Granular cell foci of the uterus in Donryu rats. J. Comp. Pathol, 119: 195-199.
-
(1998)
J. Comp. Pathol
, vol.119
, pp. 195-199
-
-
Sasahara, K.1
Ando-Lu, J.2
Nishiyama, K.3
Takahashi, M.4
Yoshida, M.5
Maekawa, A.6
-
289
-
-
0030816769
-
Detection of rodent liver carcinogen genotoxicity by the alkaline single-cell gel electrophoresis (comet) assay in multiple mouse organs (liver, lung, spleen, kidney, and bone marrow)
-
Sasaki, Y. F., Izumiyama, F., Nishidate, E., Matsusaka, N., and Tsuda, S. (1997): Detection of rodent liver carcinogen genotoxicity by the alkaline single-cell gel electrophoresis (comet) assay in multiple mouse organs (liver, lung, spleen, kidney, and bone marrow). Mutat. Res., 391:201-214.
-
(1997)
Mutat. Res
, vol.391
, pp. 201-214
-
-
Sasaki, Y.F.1
Izumiyama, F.2
Nishidate, E.3
Matsusaka, N.4
Tsuda, S.5
-
291
-
-
0016437314
-
The micronucleus test
-
Schmid, W. (1975): The micronucleus test. Mutat. Res, 31:9-15.
-
(1975)
Mutat. Res
, vol.31
, pp. 9-15
-
-
Schmid, W.1
-
293
-
-
0015755427
-
Enhancement of tumor development of physically-stressed mice inoculated with an oncogenic virus
-
Seifter, E., Rettura, G., Zisblatt, M., Levenson, S M., Levine, N., Davidson, A., and Seigter, J. (1973): Enhancement of tumor development of physically-stressed mice inoculated with an oncogenic virus. Experientia, 29: 1379-1882.
-
(1973)
Experientia
, vol.29
, pp. 1379-1882
-
-
Seifter, E.1
Rettura, G.2
Zisblatt, M.3
Levenson, S.M.4
Levine, N.5
Davidson, A.6
Seigter, J.7
-
295
-
-
0033024643
-
Safety assessment of biotechnology-derived pharmaceuticals: ICH and beyond
-
Serabian, M. A. and Pilaro, A. M. (1999): Safety assessment of biotechnology-derived pharmaceuticals: ICH and beyond. Toxicol. Pathol., 27:27-31
-
(1999)
Toxicol. Pathol
, vol.27
, pp. 27-31
-
-
Serabian, M.A.1
Pilaro, A.M.2
-
296
-
-
84988175795
-
Analytical methods validation: Bioavailability, bioequivalence and pharmacokinetic studies
-
Shah, V. P., Midha, K. K., Dighe, S., McGilveray, I. J., Skelly, J. P. et al. (1992): Analytical methods validation: bioavailability, bioequivalence and pharmacokinetic studies. J. Pharmaceut. Res, 81:309-312.
-
(1992)
J. Pharmaceut. Res
, vol.81
, pp. 309-312
-
-
Shah, V.P.1
Midha, K.K.2
Dighe, S.3
McGilveray, I.J.4
Skelly, J.P.5
-
297
-
-
0032609736
-
Medium-term bioassays in rats for rapid detection of the carcinogenic potential of chemicals
-
edited by D. B. McGregor, J. M. Rice, and S. Venitt, IARC Publ. No. 146, International Agency for Research on Cancer, Lyon, France
-
Shirai, T., Hirose, M., and Ito, N. (1999): Medium-term bioassays in rats for rapid detection of the carcinogenic potential of chemicals. In: The Use of Short- and MediumTerm Tests for Carcinogenic Hazard Evaluation, edited by D. B. McGregor, J. M. Rice, and S. Venitt, IARC Publ. No. 146, pp. 251-271. International Agency for Research on Cancer, Lyon, France.
-
(1999)
The Use of Short- and MediumTerm Tests for Carcinogenic Hazard Evaluation
, pp. 251-271
-
-
Shirai, T.1
Hirose, M.2
Ito, N.3
-
298
-
-
2642656479
-
Long-term studies on the potential carcinogenicity of artificial sweeteners in non-human primates
-
edited by B. Guggenheim, Karger, Basel, Switzerland
-
Sieber, S. M. and Adamson, R. H. (1978): Long-term studies on the potential carcinogenicity of artificial sweeteners in non-human primates. In: Health and Sugar Substitutes, edited by B. Guggenheim, pp. 266-271. Karger, Basel, Switzerland.
-
(1978)
Health and Sugar Substitutes
, pp. 266-271
-
-
Sieber, S.M.1
Adamson, R.H.2
-
299
-
-
0033742687
-
Mechanisms of nongenotoxic carcinogenesis and assessment of the human hazard
-
Silva, L. B. and van der Laan, J. W. (2000): Mechanisms of nongenotoxic carcinogenesis and assessment of the human hazard. Regul. Toxicol. Pharmacol, 32:135-143.
-
(2000)
Regul. Toxicol. Pharmacol
, vol.32
, pp. 135-143
-
-
Silva, L.B.1
van der Laan, J.W.2
-
300
-
-
0016759516
-
Vitamin A and benzo(a)pyrene carcinogenesis in the respiratory tract of hamsters fed a synthetic diet
-
Smith, D. M., Rogers, A. E., and Newberne, P. M. (1975): Vitamin A and benzo(a)pyrene carcinogenesis in the respiratory tract of hamsters fed a synthetic diet. Cancer Res., 35:1485-1488.
-
(1975)
Cancer Res
, vol.35
, pp. 1485-1488
-
-
Smith, D.M.1
Rogers, A.E.2
Newberne, P.M.3
-
301
-
-
33847289085
-
A method of chronic nose-only exposures of laboratory animals to inhaled fibrous aerosols
-
edited by H. P. Leong, Ann Arbor Science, Ann Arbor, MI
-
Smith, D. M., Ortiz, L. W., Archuleta, R. F., Spalding, J. F., Tillery, M. I., Ettinger, H. J., and Thomas, R. G. (1981): A method of chronic nose-only exposures of laboratory animals to inhaled fibrous aerosols. In: Inhalation Toxicology and Technology, edited by H. P. Leong, pp. 89-105. Ann Arbor Science, Ann Arbor, MI.
-
(1981)
Inhalation Toxicology and Technology
, pp. 89-105
-
-
Smith, D.M.1
Ortiz, L.W.2
Archuleta, R.F.3
Spalding, J.F.4
Tillery, M.I.5
Ettinger, H.J.6
Thomas, R.G.7
-
302
-
-
3242879065
-
Early occurrence of spontaneous tumors in CD-1 mice and Sprague-Dawley rats
-
Son, W. C. and Gopinath, C. (2004): Early occurrence of spontaneous tumors in CD-1 mice and Sprague-Dawley rats. Toxicol. Pathol., 32:371-374.
-
(2004)
Toxicol. Pathol
, vol.32
, pp. 371-374
-
-
Son, W.C.1
Gopinath, C.2
-
303
-
-
0003979387
-
-
DHHS Publ. (NIH)76-801. National Cancer Institute, Bethesda, MD
-
Sontag, J. R., Page, N. P., and Safiotti, U. (1976): Guidelines for Carcinogen Bioassay in Small Rodents. DHHS Publ. (NIH)76-801. National Cancer Institute, Bethesda, MD.
-
(1976)
Guidelines for Carcinogen Bioassay in Small Rodents
-
-
Sontag, J.R.1
Page, N.P.2
Safiotti, U.3
-
304
-
-
0033001244
-
Development of a transgenic mouse model for carcinogenesis bio-assays: Evaluation of chemically induced skin tumors in Tg.AC mice
-
Spalding, J. W., French, J. E., Tice, R. R., Furedi-Machek, M., Haseman, J. K., and Tennant, R. W. (1999): Development of a transgenic mouse model for carcinogenesis bio-assays: evaluation of chemically induced skin tumors in Tg.AC mice. Toxicol. Sci., 49:241-254.
-
(1999)
Toxicol. Sci
, vol.49
, pp. 241-254
-
-
Spalding, J.W.1
French, J.E.2
Tice, R.R.3
Furedi-Machek, M.4
Haseman, J.K.5
Tennant, R.W.6
-
305
-
-
0035987745
-
Evaluation of the carcinogenic potential of insulin glargine (Lantus) in rats and mice
-
Stammberger, I., Bube, A., Durchfeld-Meyer, B., Donaubauer, H., and Troschau, G. (2002): Evaluation of the carcinogenic potential of insulin glargine (Lantus) in rats and mice. Int. J. Toxicol., 21:171-179.
-
(2002)
Int. J. Toxicol
, vol.21
, pp. 171-179
-
-
Stammberger, I.1
Bube, A.2
Durchfeld-Meyer, B.3
Donaubauer, H.4
Troschau, G.5
-
306
-
-
17944374237
-
/- Hemizygous knockout mouse: Overview of the available data
-
/- Hemizygous knockout mouse: overview of the available data. Toxicol. Pathol., 29(Suppl):30-50.
-
(2001)
Toxicol. Pathol
, vol.29
, pp. 30-50
-
-
Storer, R.D.1
French, J.E.2
Haseman, J.3
Hajian, G.4
LeGrand, E.K.5
Long, G.G.6
Mixon, L.A.7
Ochoa, R.8
Sagartz, J.E.9
Soper, K.A.10
-
308
-
-
0016759979
-
Tests for trend in life table analysis
-
Tarone, R. E. (1975): Tests for trend in life table analysis. Biometrika, 62:679-682.
-
(1975)
Biometrika
, vol.62
, pp. 679-682
-
-
Tarone, R.E.1
-
309
-
-
3242681462
-
The stability of historical control data for common neoplasms in laboratory rats: Adrenal gland (medulla), mammary gland, liver, endocrine pancreas, and pituitary gland
-
Tennekes, H., Gembardt, C., Dammann, M., and van Raven-zwaay, B. (2004): The stability of historical control data for common neoplasms in laboratory rats: adrenal gland (medulla), mammary gland, liver, endocrine pancreas, and pituitary gland. Regul. Toxicol. Pharmacol, 40(1):18-27.
-
(2004)
Regul. Toxicol. Pharmacol
, vol.40
, Issue.1
, pp. 18-27
-
-
Tennekes, H.1
Gembardt, C.2
Dammann, M.3
van Raven-zwaay, B.4
-
310
-
-
8844244093
-
The stability of historical control data for common neoplasms in laboratory rats and the implications for carcinogenic risk assessment
-
Tennekes, H., Kaufmann, W., Dammann, M., and van Ravenzwaay, B. (2004): The stability of historical control data for common neoplasms in laboratory rats and the implications for carcinogenic risk assessment. Regul. Tox-icol. Pharmacol, 40(3):293-304.
-
(2004)
Regul. Tox-icol. Pharmacol
, vol.40
, Issue.3
, pp. 293-304
-
-
Tennekes, H.1
Kaufmann, W.2
Dammann, M.3
van Ravenzwaay, B.4
-
311
-
-
0028998001
-
A study of the mechanism of butachlor-associated gastric neoplasms in Sprague-Dawley rats
-
Thake, D. C., Iatropoulos, M. J., Hard, G. C., Hotz, K. J., Wang, C.-X., Williams, G. M., and Wilson, A. G. E. (1995): A study of the mechanism of butachlor-associated gastric neoplasms in Sprague-Dawley rats. Exp. Toxicol. Pathol., 47:107-116.
-
(1995)
Exp. Toxicol. Pathol
, vol.47
, pp. 107-116
-
-
Thake, D.C.1
Iatropoulos, M.J.2
Hard, G.C.3
Hotz, K.J.4
Wang, C.-X.5
Williams, G.M.6
Wilson, A.G.E.7
-
312
-
-
0025735386
-
Evidence for and possible mechanisms of non-genotoxic carcinogenesis in the rodent thyroid
-
Thomas, G. A. and Williams, E. D. (1991): Evidence for and possible mechanisms of non-genotoxic carcinogenesis in the rodent thyroid. Mutat. Res., 248:357-370.
-
(1991)
Mutat. Res
, vol.248
, pp. 357-370
-
-
Thomas, G.A.1
Williams, E.D.2
-
313
-
-
0028297757
-
Tumor incidence in a chemical carcinogenesis study of nonhuman primates
-
Thorgiersson, U., Dalgard, D., Reeves, J., and Adamson, R. (1994): Tumor incidence in a chemical carcinogenesis study of nonhuman primates. Regul. Toxicol. Pharmacol., 19:130-151.
-
(1994)
Regul. Toxicol. Pharmacol
, vol.19
, pp. 130-151
-
-
Thorgiersson, U.1
Dalgard, D.2
Reeves, J.3
Adamson, R.4
-
314
-
-
0028355453
-
Survival, body weight, and spontaneous neoplasms in ad libitum-fed and food-restricted Fischer-344 rats
-
Thurman, J. D., Bucci, T. J., Hart, R. W., and Torturro, A. (1994): Survival, body weight, and spontaneous neoplasms in ad libitum-fed and food-restricted Fischer-344 rats. Toxicol. Pathol., 22:1-9.
-
(1994)
Toxicol. Pathol
, vol.22
, pp. 1-9
-
-
Thurman, J.D.1
Bucci, T.J.2
Hart, R.W.3
Torturro, A.4
-
315
-
-
0024354338
-
Overview of perinatal and multigeneration carcinogenesis
-
edited by N. P. Napalkov, J. M. Rice, L. Tomatis, and H. Yamasaki, IARC Publ. No. 96, International Agency for Research on Cancer, Lyon, France
-
Tomatis, L. (1989): Overview of perinatal and multigeneration carcinogenesis. In: Perinatal and Multigeneration Carcinogenesis, edited by N. P. Napalkov, J. M. Rice, L. Tomatis, and H. Yamasaki, IARC Publ. No. 96, pp. 1-15. International Agency for Research on Cancer, Lyon, France.
-
(1989)
Perinatal and Multigeneration Carcinogenesis
, pp. 1-15
-
-
Tomatis, L.1
-
316
-
-
51249163134
-
Brown adipose tissue: From thermal physiology to bioenergetics
-
Trayhurn, P. (1993): Brown adipose tissue: from thermal physiology to bioenergetics. J. Biosci., 18:161-173.
-
(1993)
J. Biosci
, vol.18
, pp. 161-173
-
-
Trayhurn, P.1
-
317
-
-
0032602331
-
Shortand medium-term carcinogenicity tests
-
edited by D. B. McGregor, J. M. Rice, and S. Venitt, IARC Publ. No. 146, International Agency for Research on Cancer, Lyon, France
-
Tsuda, H., Park, C. B., and Moore, M. A. (1999): Shortand medium-term carcinogenicity tests. In: The Use of Short- and Medium-Term Tests for Carcinogenic Hazard Evaluation, edited by D. B. McGregor, J. M. Rice, and S. Venitt, IARC Publ. No. 146, pp. 203-249. International Agency for Research on Cancer, Lyon, France.
-
(1999)
The Use of Short- and Medium-Term Tests for Carcinogenic Hazard Evaluation
, pp. 203-249
-
-
Tsuda, H.1
Park, C.B.2
Moore, M.A.3
-
318
-
-
0026794395
-
Comparison of the ECL-cell frequency in the stomachs of 3 different rat strains
-
Tuch, K., Ockert, D., Hauschke, D., and Christ, B. (1992): Comparison of the ECL-cell frequency in the stomachs of 3 different rat strains. Pathol. Res. Pract., 188:672-675.
-
(1992)
Pathol. Res. Pract
, vol.188
, pp. 672-675
-
-
Tuch, K.1
Ockert, D.2
Hauschke, D.3
Christ, B.4
-
319
-
-
0022706238
-
Decreased number of spindle and cytoplasmic microtubules in hamster embryo cells treated with a carcinogen, diethylstilbestrol
-
Tucker, R. W. and Barrett, J. C. (1986): Decreased number of spindle and cytoplasmic microtubules in hamster embryo cells treated with a carcinogen, diethylstilbestrol. Cancer Res., 46:2088-2095.
-
(1986)
Cancer Res
, vol.46
, pp. 2088-2095
-
-
Tucker, R.W.1
Barrett, J.C.2
-
320
-
-
67049126715
-
Predicting carcinogenicity: Peroxisome proliferators
-
edited by K. T. Kitchin, Marcel Dekker, New York
-
Tugwood, J. D. and Elcombe, C. R. (1999): Predicting carcinogenicity: peroxisome proliferators. In: Carcinoge-nicity, edited by K. T. Kitchin, pp. 337-360. Marcel Dekker, New York.
-
(1999)
Carcinoge-nicity
, pp. 337-360
-
-
Tugwood, J.D.1
Elcombe, C.R.2
-
322
-
-
0028252216
-
Histiocytic sarcoma
-
Tumors of the Mouse, edited by V. S. Turusov and U. Mohr, IARC Publ. No. 111. International Agency for Research on Cancer, Lyon, France
-
Turusov, V. S. (1994): Histiocytic sarcoma. In: Pathology of Tumours in Laboratory Animals. Vol. II. Tumors of the Mouse, edited by V. S. Turusov and U. Mohr, IARC Publ. No. 111, pp. 671-680. International Agency for Research on Cancer, Lyon, France.
-
(1994)
Pathology of Tumours in Laboratory Animals
, vol.2
, pp. 671-680
-
-
Turusov, V.S.1
-
323
-
-
0036742877
-
Hepatoblastomas in mice in the U.S. National Toxicology Program (NTP studies)
-
Turusov, V. S., Torii, M., Sills, R. C., Willson, G. A., Herbert, R. A., Hailey, J., Haseman, J. K., and Boorman, G. A. (2002): Hepatoblastomas in mice in the U.S. National Toxicology Program (NTP studies). Toxicol. Pathol., 30:580-591.
-
(2002)
Toxicol. Pathol
, vol.30
, pp. 580-591
-
-
Turusov, V.S.1
Torii, M.2
Sills, R.C.3
Willson, G.A.4
Herbert, R.A.5
Hailey, J.6
Haseman, J.K.7
Boorman, G.A.8
-
326
-
-
85132687516
-
Food Quality Protection Act Amendment
-
U.S. Congress. (1998): Food Quality Protection Act Amendment, Public Law 105-324.
-
(1998)
Public Law
, pp. 105-324
-
-
Congress, U.S.1
-
327
-
-
85132686789
-
-
CFR 9, Parts 1, 2
-
U.S. Department of Agriculture. (1989): Animal Welfare Rules, CFR 9, Parts 1, 2.
-
(1989)
Animal Welfare Rules
-
-
-
328
-
-
0003633755
-
-
Publ. No. NIH 77-23. U.S. Department of Health and Welfare, Washington, D.C
-
U.S. DHW. (1977): Guide for Care and Use of Laboratory Animals, Publ. No. NIH 77-23. U.S. Department of Health and Welfare, Washington, D.C.
-
(1977)
Guide for Care and Use of Laboratory Animals
-
-
-
329
-
-
0001372175
-
Guidelines for carcinogen risk assessment
-
U.S. EPA. (1986): Guidelines for carcinogen risk assessment. Fed. Reg, 51:33992-34005.
-
(1986)
Fed. Reg
, vol.51
, pp. 33992-34005
-
-
-
330
-
-
85132687656
-
-
Draft 12-28-90. Scientific Systems Staff, Office of Information Resources Management U.S. Environmental Protection Agency, Washington, D.C
-
U.S. EPA (1990): Good Automated Practices, Draft 12-28-90. Scientific Systems Staff, Office of Information Resources Management U.S. Environmental Protection Agency, Washington, D.C.
-
(1990)
Good Automated Practices
-
-
-
331
-
-
0001521326
-
Alpha 2μ-Globulin: Association with Chemically Induced Renal Toxicity and Neoplasia in the Male Rat, Risk Assessment Forum, EPA/625/3-91/019F. U.S. Environmental Protection Agency, Washington, D.C. 332. U.S. EPA. (1992): A cross-species scaling factor for carcinogen risk assessment based on equivalence of mg/kg/day: Notice
-
U.S. EPA. (1991): Alpha 2μ-Globulin: Association with Chemically Induced Renal Toxicity and Neoplasia in the Male Rat, Risk Assessment Forum, EPA/625/3-91/019F. U.S. Environmental Protection Agency, Washington, D.C. 332. U.S. EPA. (1992): A cross-species scaling factor for carcinogen risk assessment based on equivalence of mg/kg/day: notice. Fed. Reg., 57:24152-24173.
-
(1991)
Fed. Reg
, vol.57
, pp. 24152-24173
-
-
-
332
-
-
0003914636
-
Guidelines for exposure assessment
-
U.S. EPA. (1992): Guidelines for exposure assessment. Fed. Reg., 57:22888-22938.
-
(1992)
Fed. Reg
, vol.57
, pp. 22888-22938
-
-
-
333
-
-
0000060569
-
Proposed guidelines for carcinogen risk assessment
-
U.S. EPA. (1996): Proposed guidelines for carcinogen risk assessment. Fed. Reg., 61:17960-18011.
-
(1996)
Fed. Reg
, vol.61
, pp. 17960-18011
-
-
-
334
-
-
0003432401
-
-
EPA/600/P-95-002A. Office of Research and Development, U.S. Environmental Protection Agency, Washington, D.C
-
U.S. EPA. (1997): Exposure Factors Handbook, EPA/600/P-95-002A. Office of Research and Development, U.S. Environmental Protection Agency, Washington, D.C.
-
(1997)
Exposure Factors Handbook
-
-
-
335
-
-
85030952736
-
-
EPA/630/P-03/001A. U.S. Environmental Protection Agency, Washington, D.C
-
U.S. EPA. (2003): Final Draft Guidelines for Carcinogenic Risk Assessment, EPA/630/P-03/001A. U.S. Environmental Protection Agency, Washington, D.C. (www.epa.gov/ncea/raf/cancer2003.htm).
-
(2003)
Final Draft Guidelines for Carcinogenic Risk Assessment
-
-
-
337
-
-
0039625191
-
Good Laboratory Practices for nonclinical laboratory studies, Code of Federal Regulations, Title 21, Part 58
-
U.S. FDA. (1978): Good Laboratory Practices for nonclinical laboratory studies, Code of Federal Regulations, Title 21, Part 58. Fed. Reg, 43:59986-60025.
-
(1978)
Fed. Reg
, vol.43
, pp. 59986-60025
-
-
-
339
-
-
85132688750
-
Advisory committee for protocols for safety evaluation, panel on carcinogenesis: Report on cancer testing in the safety of food additives and pesticides
-
U.S. FDA. (1993): Advisory committee for protocols for safety evaluation, panel on carcinogenesis: report on cancer testing in the safety of food additives and pesticides. Toxicol. Appl. Pharmacol., 20:419-438.
-
(1993)
Toxicol. Appl. Pharmacol
, vol.20
, pp. 419-438
-
-
-
340
-
-
84920300738
-
International Conference on Harmonization, draft guideline on dose selection for carcinogenicity studies of pharmaceuticals
-
U.S. FDA. (1994): International Conference on Harmonization, draft guideline on dose selection for carcinogenicity studies of pharmaceuticals. Fed. Reg., 59:9752-9760 (http://www.ifpma.org/ich5s.html).
-
(1994)
Fed. Reg
, vol.59
, pp. 9752-9760
-
-
-
342
-
-
0000493162
-
Food additives: Threshold of regulation for substances used in food contact articles
-
U.S. FDA. (1995): Food additives: threshold of regulation for substances used in food contact articles. Fed. Reg., 60:36582-36596.
-
(1995)
Fed. Reg
, vol.60
, pp. 36582-36596
-
-
-
343
-
-
0011223898
-
International Conference on Harmonization, guidance on preclinical safety evaluation of biotechnology-derived pharmaceuticals
-
U.S. FDA. (1997): International Conference on Harmonization, guidance on preclinical safety evaluation of biotechnology-derived pharmaceuticals. Fed. Reg, 62:61515-61519 (http://www.iben.gov).
-
(1997)
Fed. Reg
, vol.62
, pp. 61515-61519
-
-
-
344
-
-
0001184877
-
International Conference on Harmonization, guidelines on impurities in new drug products
-
U.S. FDA. (1997): International Conference on Harmonization, guidelines on impurities in new drug products. Fed. Reg., 62:27454-27461.
-
(1997)
Fed. Reg
, vol.62
, pp. 27454-27461
-
-
-
346
-
-
2442536410
-
Revision of the definition of the term 'no residue' in the new animal drug regulations
-
U.S. FDA. (2002): Revision of the definition of the term 'no residue' in the new animal drug regulations. Fed. Reg., 67:78172-78174.
-
(2002)
Fed. Reg
, vol.67
, pp. 78172-78174
-
-
-
348
-
-
13844269362
-
DNA adduct of the mitomycin C metabolite 2,7-diaminonitrosene is a non-toxic and nonmutagenic DNA lesion in vitro and in vivo
-
Utzat, C. D., Clement, C. C., Ramos, L. A., Das, A., Tomasz, M., and Basu, A. K. (2005): DNA adduct of the mitomycin C metabolite 2,7-diaminonitrosene is a non-toxic and nonmutagenic DNA lesion in vitro and in vivo. Chem. Res. Toxicol., 18:213-223.
-
(2005)
Chem. Res. Toxicol
, vol.18
, pp. 213-223
-
-
Utzat, C.D.1
Clement, C.C.2
Ramos, L.A.3
Das, A.4
Tomasz, M.5
Basu, A.K.6
-
349
-
-
0031080023
-
The utility of two rodent species in carcinogenic risk assessment of pharmaceuticals in Europe
-
van Oosterhout, J. P. J., van der Laan, J. W., de Waal, E. J., Olejniczak, K., Hilgenfeld, M., Schmidt, V., and Bass, R. (1997): The utility of two rodent species in carcinogenic risk assessment of pharmaceuticals in Europe. Regul. Toxicol. Pharmacol., 25:6-17.
-
(1997)
Regul. Toxicol. Pharmacol
, vol.25
, pp. 6-17
-
-
van Oosterhout, J.P.J.1
van der Laan, J.W.2
de Waal, E.J.3
Olejniczak, K.4
Hilgenfeld, M.5
Schmidt, V.6
Bass, R.7
-
350
-
-
0031775632
-
Use of DNA repair-deficient XPA transgenic mice in short-term carcinogenicity testing
-
van Steeg, H., Klein, H., Beems, R. B., and van Kreijl, C. F. (1998): Use of DNA repair-deficient XPA transgenic mice in short-term carcinogenicity testing. Toxicol. Pathol., 26:742-749.
-
(1998)
Toxicol. Pathol
, vol.26
, pp. 742-749
-
-
van Steeg, H.1
Klein, H.2
Beems, R.B.3
van Kreijl, C.F.4
-
351
-
-
0041548415
-
Induction of drug metabolizing enzymes in liver microsomes of mice and rats by softwood bedding
-
Vessel, E. S. (1967): Induction of drug metabolizing enzymes in liver microsomes of mice and rats by softwood bedding. Science, 157:1057-1058.
-
(1967)
Science
, vol.157
, pp. 1057-1058
-
-
Vessel, E.S.1
-
352
-
-
0033035054
-
Phenobarbital, β-naphthoflavone, clofibrate, and pregnenolone-16a-carbon-itrile do not affect hepatic thyroid hormone UDP-glucu-ronosyl transferase activity, and thyroid gland function in mice
-
Viollon-Abadie, C., Lassere, D., Debruyne, E., Nicod, L., Carmichael, N., and Richert, L. (1999): Phenobarbital, β-naphthoflavone, clofibrate, and pregnenolone-16a-carbon-itrile do not affect hepatic thyroid hormone UDP-glucu-ronosyl transferase activity, and thyroid gland function in mice. Toxicol. Appl. Pharmacol, 155:1-12.
-
(1999)
Toxicol. Appl. Pharmacol
, vol.155
, pp. 1-12
-
-
Viollon-Abadie, C.1
Lassere, D.2
Debruyne, E.3
Nicod, L.4
Carmichael, N.5
Richert, L.6
-
353
-
-
77957176959
-
Spontaneous neoplasms in control Wistar rats
-
Walsh, K. M. and Poteracki, J. (1994): Spontaneous neoplasms in control Wistar rats. Fundam. Appl. Toxicol., 23: 65-72.
-
(1994)
Fundam. Appl. Toxicol
, vol.23
, pp. 65-72
-
-
Walsh, K.M.1
Poteracki, J.2
-
354
-
-
0021934758
-
Chemoprevention of cancer
-
Wattenberg, L. W. (1985): Chemoprevention of cancer. Cancer Res., 45:1-8.
-
(1985)
Cancer Res
, vol.45
, pp. 1-8
-
-
Wattenberg, L.W.1
-
355
-
-
0020671819
-
History of the bioassay program of the National Cancer Institute
-
Weisburger, E. K. (1983): History of the bioassay program of the National Cancer Institute. Prog. Exp. Tumor Res., 26:187-201.
-
(1983)
Prog. Exp. Tumor Res
, vol.26
, pp. 187-201
-
-
Weisburger, E.K.1
-
356
-
-
0019792758
-
Carcinogen testing: Current problems and new approaches
-
Weisburger, J. H. and Williams, G. M. (1981): Carcinogen testing: current problems and new approaches. Science, 214:401-407, 1981.
-
(1981)
Science
, vol.214
, pp. 401-407
-
-
Weisburger, J.H.1
Williams, G.M.2
-
357
-
-
0001146919
-
Bioassay of carcinogens: In vitro and in vivo tests
-
2nd ed., ACS Monograph 182, American Chemical Society, Washington, D.C
-
Weisburger, J. H. and Williams, G. M. (1984): Bioassay of carcinogens: in vitro and in vivo tests. In: Chemical Carcinogenesis, Vol. 2, 2nd ed., ACS Monograph 182, pp. 1323-1373. American Chemical Society, Washington, D.C.
-
(1984)
Chemical Carcinogenesis
, vol.2
, pp. 1323-1373
-
-
Weisburger, J.H.1
Williams, G.M.2
-
358
-
-
0002067439
-
Causes of cancer
-
edited by G. P. Murphy, W. Lawrence, Jr., and R. E. Lenhard, Jr., American Cancer Society, Atlanta, GA
-
Weisburger, J. H. and Williams, G. M. (1995): Causes of cancer. In: American Cancer Society Textbook of Clinical Oncology, edited by G. P. Murphy, W. Lawrence, Jr., and R. E. Lenhard, Jr., pp. 10-39. American Cancer Society, Atlanta, GA.
-
(1995)
American Cancer Society Textbook of Clinical Oncology
, pp. 10-39
-
-
Weisburger, J.H.1
Williams, G.M.2
-
359
-
-
0001657498
-
Benign lipomatous tumors and liposarcoma
-
Mosby, St. Louis, MO
-
Weiss, S. W. and Goldblum, J. R. (2001): Benign lipomatous tumors and liposarcoma. In: Soft Tissue Tumors, pp. 571-695. Mosby, St. Louis, MO.
-
(2001)
Soft Tissue Tumors
, pp. 571-695
-
-
Weiss, S.W.1
Goldblum, J.R.2
-
360
-
-
0026598008
-
International cancer risk assessment: The impact of biologic mechanisms
-
Whysner, J. and Williams, G. M. (1992): International cancer risk assessment: the impact of biologic mechanisms, Regul. Toxicol. Pharmacol., 15:41-50.
-
(1992)
Regul. Toxicol. Pharmacol
, vol.15
, pp. 41-50
-
-
Whysner, J.1
Williams, G.M.2
-
361
-
-
0029769309
-
Butylated hydroxyanisole mechanistic data and risk assessment: Conditional species-specific cytotoxicity, enhanced cell proliferation, and tumor promotion
-
Whysner, J. and Williams, G. M. (1996): Butylated hydroxyanisole mechanistic data and risk assessment: conditional species-specific cytotoxicity, enhanced cell proliferation, and tumor promotion. Pharmacol. Ther, 71(1/2): 137-151.
-
(1996)
Pharmacol. Ther
, vol.71
, Issue.1-2
, pp. 137-151
-
-
Whysner, J.1
Williams, G.M.2
-
362
-
-
0029762765
-
Phenobarbital mechanistic data and risk assessment: Enzyme induction, enhanced cell proliferation, and tumor promotion
-
Whysner, J., Ross, P. M., and Williams, G. M. (1996): Phenobarbital mechanistic data and risk assessment: enzyme induction, enhanced cell proliferation, and tumor promotion. Pharmacol. Ther., 71(1/2):153-191.
-
(1996)
Pharmacol. Ther
, vol.71
, Issue.1-2
, pp. 153-191
-
-
Whysner, J.1
Ross, P.M.2
Williams, G.M.3
-
363
-
-
0004192590
-
Definition of a human cancer hazard
-
Banbury Report 25, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
-
Williams, G. M. (1987): Definition of a human cancer hazard. In: Nongenotoxic Mechanisms in Carcinogenesis, Banbury Report 25, pp. 367-380. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
-
(1987)
Nongenotoxic Mechanisms in Carcinogenesis
, pp. 367-380
-
-
Williams, G.M.1
-
364
-
-
0024593070
-
Methods for evaluating chemical genotoxicity
-
Williams, G. M. (1989): Methods for evaluating chemical genotoxicity. Ann. Rev. Pharmacol. Toxicol., 29:189-211.
-
(1989)
Ann. Rev. Pharmacol. Toxicol
, vol.29
, pp. 189-211
-
-
Williams, G.M.1
-
365
-
-
27444434452
-
Interactive carcinogenesis in the liver
-
edited by P. Bannasch, D. Keppler, and G. Weber, Falk Symposium 51, Kluwer, Boston, MA
-
Williams, G. M. (1989): Interactive carcinogenesis in the liver. In: Liver Cell Carcinoma, edited by P. Bannasch, D. Keppler, and G. Weber, Falk Symposium 51, pp. 197-216. Kluwer, Boston, MA.
-
(1989)
Liver Cell Carcinoma
, pp. 197-216
-
-
Williams, G.M.1
-
366
-
-
0025168709
-
Screening procedures for evaluating the potential carcinogenicity of food-packaging chemicals
-
Williams, G. M. (1990): Screening procedures for evaluating the potential carcinogenicity of food-packaging chemicals. Regul. Toxicol. Pharmacol., 12:30-40.
-
(1990)
Regul. Toxicol. Pharmacol
, vol.12
, pp. 30-40
-
-
Williams, G.M.1
-
367
-
-
0027048538
-
DNA reactive and epigenetic carcinogens
-
Williams, G. M. (1992): DNA reactive and epigenetic carcinogens. Exp. Toxicol. Pathol., 44:457-464.
-
(1992)
Exp. Toxicol. Pathol
, vol.44
, pp. 457-464
-
-
Williams, G.M.1
-
368
-
-
0010254774
-
Chemicals with carcinogenic activity in the rodent liver; a mechanistic evaluation of human risk
-
Williams, G. M. (1997): Chemicals with carcinogenic activity in the rodent liver; a mechanistic evaluation of human risk. Cancer Lett., 118:1-14.
-
(1997)
Cancer Lett
, vol.118
, pp. 1-14
-
-
Williams, G.M.1
-
369
-
-
0032618379
-
Chemical-induced preneoplastic lesions in rodents as indicators of carcinogenic activity
-
of Short- and Medium-Term Tests for Carcinogens and Data on Genetic Effects in Carcinogenic Hazard Evaluations, edited by D. B. McGregor, J. M. Rice, and S. Venitt, IARC Publ. No. 146, International Agency for Research on Cancer, Lyon, France
-
Williams, G. M. (1999): Chemical-induced preneoplastic lesions in rodents as indicators of carcinogenic activity. In: The Use of Short- and Medium-Term Tests for Carcinogens and Data on Genetic Effects in Carcinogenic Hazard Evaluations, edited by D. B. McGregor, J. M. Rice, and S. Venitt, IARC Publ. No. 146, pp. 185-202. International Agency for Research on Cancer, Lyon, France.
-
(1999)
The Use
, pp. 185-202
-
-
Williams, G.M.1
-
370
-
-
0032861974
-
Mechanistic considerations in cancer risk assessment
-
Williams, G. M. (1999): Mechanistic considerations in cancer risk assessment. Inhal. Toxicol., 11:549-554.
-
(1999)
Inhal. Toxicol
, vol.11
, pp. 549-554
-
-
Williams, G.M.1
-
371
-
-
0021362644
-
Distinction between liver neoplasm promoting and syncarcinogenic effects demonstrated by exposure to phenobarbital or diethylnitrosamine either before or after N-2-fluorenylac-etamide
-
Williams, G. M. and Furuya, K. (1984): Distinction between liver neoplasm promoting and syncarcinogenic effects demonstrated by exposure to phenobarbital or diethylnitrosamine either before or after N-2-fluorenylac-etamide. Carcinogenesis, 5:171-174.
-
(1984)
Carcinogenesis
, vol.5
, pp. 171-174
-
-
Williams, G.M.1
Furuya, K.2
-
372
-
-
0000897714
-
Chemical carcinogenesis
-
edited by M. O. Amdur, J. Doull, and C. D. Klaassen, Pergamon Press, New York
-
Williams, G. M. and Weisburger, J. H. (1991): Chemical carcinogenesis. In: Toxicology: The Basic Science of Poisons, edited by M. O. Amdur, J. Doull, and C. D. Klaassen, pp. 127-200. Pergamon Press, New York.
-
(1991)
Toxicology: The Basic Science of Poisons
, pp. 127-200
-
-
Williams, G.M.1
Weisburger, J.H.2
-
373
-
-
0030451011
-
Mechanism-based risk assessment of peroxisome proliferating rodent hepatocarcinogens
-
edited by J. K. Reddy, T. Suga, G. P. Mannaerts, P. B. Lazarow, and S. Subramani, The New York Academy of Sciences, New York
-
Williams, G. M. and Perone, C. (1996): Mechanism-based risk assessment of peroxisome proliferating rodent hepatocarcinogens. In: Peroxisomes: Biology and Role in Toxicology and Disease, Vol. 804, edited by J. K. Reddy, T. Suga, G. P. Mannaerts, P. B. Lazarow, and S. Subramani, pp. 554-572. The New York Academy of Sciences, New York.
-
(1996)
Peroxisomes: Biology and Role in Toxicology and Disease
, vol.804
, pp. 554-572
-
-
Williams, G.M.1
Perone, C.2
-
374
-
-
0034470219
-
Oxidative DNA damage: Endogenous and chemically induced
-
Williams, G. M. and Jeffrey, A. M. (2000): Oxidative DNA damage: endogenous and chemically induced. Regul. Toxicol. Pharmacol., 32:283-292.
-
(2000)
Regul. Toxicol. Pharmacol
, vol.32
, pp. 283-292
-
-
Williams, G.M.1
Jeffrey, A.M.2
-
375
-
-
0002161949
-
Principles of testing for carcinogenic activity
-
4th ed., edited by A. Wallace Hayes. Taylor & Francis, Philadelphia, PA
-
Williams, G. M. and Iatropoulos, M. J. (2001): Principles of testing for carcinogenic activity. In: Principles and Methods of Toxicology, 4th ed., edited by A. Wallace Hayes. Taylor & Francis, Philadelphia, PA, pp. 959-1000.
-
(2001)
Principles and Methods of Toxicology
, pp. 959-1000
-
-
Williams, G.M.1
Iatropoulos, M.J.2
-
376
-
-
0036186764
-
Alteration of liver cell function and proliferation: Differentiation between adaptation and toxicity
-
Williams, G. M. and Iatropoulos, M. J. (2002): Alteration of liver cell function and proliferation: differentiation between adaptation and toxicity. Toxicol. Pathol., 30: 41-53.
-
(2002)
Toxicol. Pathol
, vol.30
, pp. 41-53
-
-
Williams, G.M.1
Iatropoulos, M.J.2
-
377
-
-
0019478871
-
Carcinogenicity of 3-methyl-2-naphthylamine and 3,2'-dimethyl-4-aminobiphenyl to the bladder and gastrointestinal tract of the Syrian golden hamster with atypical proliferative enteritis
-
Williams, G. M., Chandrasekaran, V., Katayama, S., and Weisburger, J. H. (1981): Carcinogenicity of 3-methyl-2-naphthylamine and 3,2'-dimethyl-4-aminobiphenyl to the bladder and gastrointestinal tract of the Syrian golden hamster with atypical proliferative enteritis. J. Natl. Cancer Inst., 67:481-488.
-
(1981)
J. Natl. Cancer Inst
, vol.67
, pp. 481-488
-
-
Williams, G.M.1
Chandrasekaran, V.2
Katayama, S.3
Weisburger, J.H.4
-
378
-
-
0019966132
-
Reliability of the hepatocyte primary culture/DNA repair test in testing of coded carcinogens and non carcinogens
-
Williams, G. M., Laspia, M. F., and Dunkel, V. C. (1982): Reliability of the hepatocyte primary culture/DNA repair test in testing of coded carcinogens and non carcinogens. Mutat. Res., 97:359-370.
-
(1982)
Mutat. Res
, vol.97
, pp. 359-370
-
-
Williams, G.M.1
Laspia, M.F.2
Dunkel, V.C.3
-
379
-
-
0024470842
-
Structure-activity relationships in the rat hepatocyte DNA-repair test for 300 chemicals
-
Williams, G. M., Mori, H., and McQueen, C. A. (1989): Structure-activity relationships in the rat hepatocyte DNA-repair test for 300 chemicals. Mutat. Res, 221:263-286.
-
(1989)
Mutat. Res
, vol.221
, pp. 263-286
-
-
Williams, G.M.1
Mori, H.2
McQueen, C.A.3
-
380
-
-
0029983563
-
Chemical carcinogen mechanisms of action and implications for testing methodology
-
Williams, G M., Iatropoulos, M. J., and Weisburger, J. H. (1996): Chemical carcinogen mechanisms of action and implications for testing methodology. Exp. Toxicol. Pathol, 48:101-111.
-
(1996)
Exp. Toxicol. Pathol
, vol.48
, pp. 101-111
-
-
Williams, G.M.1
Iatropoulos, M.J.2
Weisburger, J.H.3
-
381
-
-
0029874523
-
Risk assessment of carcinogens in food with special consideration of nongenotoxic carcinogens
-
Williams, G. M., Karbe, E., Fenner-Crisp, P., Iatropoulos, M. J., and Weisburger, J. H. (1996): Risk assessment of carcinogens in food with special consideration of nongenotoxic carcinogens. Exp. Toxicol. Pathol., 48:209-215.
-
(1996)
Exp. Toxicol. Pathol
, vol.48
, pp. 209-215
-
-
Williams, G.M.1
Karbe, E.2
Fenner-Crisp, P.3
Iatropoulos, M.J.4
Weisburger, J.H.5
-
382
-
-
0032728966
-
Diethylnitrosamine exposure-response for DNA ethylation, hepatocellular proliferation and initiation of carcinogenesis in rat liver display non-linearities and thresholds
-
Williams, G. M., Iatropoulos, M. J., Jeffrey, A. M., Luo, F. Q., Wang, C.-X., and Pittman, B. (1999): Diethylnitrosamine exposure-response for DNA ethylation, hepatocellular proliferation and initiation of carcinogenesis in rat liver display non-linearities and thresholds. Arch. Toxicol., 73:394-402.
-
(1999)
Arch. Toxicol
, vol.73
, pp. 394-402
-
-
Williams, G.M.1
Iatropoulos, M.J.2
Jeffrey, A.M.3
Luo, F.Q.4
Wang, C.-X.5
Pittman, B.6
-
383
-
-
0032819774
-
Safety assessment of butylated hydroxyanisole and butylated hydroxytoluene as antioxidant in food additives
-
Williams. G. M., Iatropoulos, M. J., and Whysner, J. (1999): Safety assessment of butylated hydroxyanisole and butylated hydroxytoluene as antioxidant in food additives. Food Chem. Toxicol, 37:1027-1038.
-
(1999)
Food Chem. Toxicol
, vol.37
, pp. 1027-1038
-
-
Williams, G.M.1
Iatropoulos, M.J.2
Whysner, J.3
-
384
-
-
0036701566
-
Anticarcinogenicity of monocyclic phenolic compounds
-
Williams, G. M., Iatropoulos, M. J., and Jeffrey, A. M. (2002): Anticarcinogenicity of monocyclic phenolic compounds. Eur. J. Cancer Prev, 11(Suppl. 2):S101-S107.
-
(2002)
Eur. J. Cancer Prev
, vol.11
, pp. S101-S107
-
-
Williams, G.M.1
Iatropoulos, M.J.2
Jeffrey, A.M.3
-
385
-
-
24644470031
-
Thresholds for DNA-reactive (genotoxic) organic carcinogens
-
Williams, G. M, Iatropoulos, M. J., and Jeffrey, A. M. (2005): Thresholds for DNA-reactive (genotoxic) organic carcinogens. J. Toxicol. Path., 18:69-77.
-
(2005)
J. Toxicol. Path
, vol.18
, pp. 69-77
-
-
Williams, G.M.1
Iatropoulos, M.J.2
Jeffrey, A.M.3
-
386
-
-
0030250456
-
U.S. Environmental Protection Agency guidelines for carcinogen risk assessment: Past and future
-
Wiltse, J. and Dellarco, V. L. (1996): U.S. Environmental Protection Agency guidelines for carcinogen risk assessment: past and future. Mutat. Res, 365:3-15.
-
(1996)
Mutat. Res
, vol.365
, pp. 3-15
-
-
Wiltse, J.1
Dellarco, V.L.2
-
388
-
-
0035250772
-
Genetic risks of antiviral nucleoside analogues: A survey
-
Wutzler, P. and Thust, R. (2001): Genetic risks of antiviral nucleoside analogues: a survey. Antiviral Res., 49:55-74.
-
(2001)
Antiviral Res
, vol.49
, pp. 55-74
-
-
Wutzler, P.1
Thust, R.2
-
389
-
-
0031977910
-
Validation of transgenic mice in carrying the human prototype c-Ha-ras gene as a bioassay model for rapid carcinogenicity testing
-
Yamamoto, S., Urano, K., Koizumi, H., Wakana, S., Hioki, K., Mitsumori, K., Kurokawa, Y., Hayashi, Y., and Nomura, T. (1998): Validation of transgenic mice in carrying the human prototype c-Ha-ras gene as a bioassay model for rapid carcinogenicity testing. Environ. Health Perspect, 106:57-69.
-
(1998)
Environ. Health Perspect
, vol.106
, pp. 57-69
-
-
Yamamoto, S.1
Urano, K.2
Koizumi, H.3
Wakana, S.4
Hioki, K.5
Mitsumori, K.6
Kurokawa, Y.7
Hayashi, Y.8
Nomura, T.9
-
390
-
-
0032465960
-
Identification of rodent carcinogens and non-carcinogens using genetic toxicity tests: Premises, promises, and performance
-
Zeiger, R. (1998): Identification of rodent carcinogens and non-carcinogens using genetic toxicity tests: premises, promises, and performance. Regul. Toxicol. Pharmacol., 28:85-95.
-
(1998)
Regul. Toxicol. Pharmacol
, vol.28
, pp. 85-95
-
-
Zeiger, R.1
|