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Volumn 36, Issue 1, 1997, Pages 79-89

Chronic toxicity and carcinogenic evaluation of diisononyl phthalate in rats

Author keywords

[No Author keywords available]

Indexed keywords

PHTHALIC ACID; PHTHALIC ACID DIISONONYL ESTER; PLASTICIZER; UNCLASSIFIED DRUG;

EID: 26844508008     PISSN: 02720590     EISSN: None     Source Type: Journal    
DOI: 10.1006/faat.1997.2286     Document Type: Article
Times cited : (66)

References (67)
  • 3
    • 0022994185 scopus 로고
    • Species differences in the response of cultured hepatocytes to phthalate esters
    • Benford, D. J., Patel, S., and Reavy, H. J. (1986). Species differences in the response of cultured hepatocytes to phthalate esters. Food Chem. Toxicol. 24, 799-800.
    • (1986) Food Chem. Toxicol. , vol.24 , pp. 799-800
    • Benford, D.J.1    Patel, S.2    Reavy, H.J.3
  • 4
    • 0002784616 scopus 로고
    • A thirteen week feeding study on diisononyl phthalate (DINP) in rats
    • Bird, M. G., Kapp, R. W., Keller, C. A., and Lington, A. W. (1986). A thirteen week feeding study on diisononyl phthalate (DINP) in rats. Toxicologist 6(1), 302.
    • (1986) Toxicologist , vol.6 , Issue.1 , pp. 302
    • Bird, M.G.1    Kapp, R.W.2    Keller, C.A.3    Lington, A.W.4
  • 5
    • 0011161667 scopus 로고
    • Subchronic and chronic oral studies of diisononyl phthalate (DINP) in F-344 rats: Effects on hepatic peroxisome induction
    • Bird, M. G., Lington, A. W., and Cockrell, B. A. (1987). Subchronic and chronic oral studies of diisononyl phthalate (DINP) in F-344 rats: Effects on hepatic peroxisome induction. Toxicologist 7, 56.
    • (1987) Toxicologist , vol.7 , pp. 56
    • Bird, M.G.1    Lington, A.W.2    Cockrell, B.A.3
  • 8
    • 84889551557 scopus 로고    scopus 로고
    • Workshop overview. National Toxicology Program studies: Principles in dose selection and application of mechanistically based risk assessment
    • Bucher, J. R., Portier, C. J., Goodman, J. I., Faustman, E. M., and Lucier, G. W. (1996) Workshop overview. National Toxicology Program studies: Principles in dose selection and application of mechanistically based risk assessment. Fundam. Appl. Toxicol. 31, 1-8.
    • (1996) Fundam. Appl. Toxicol. , vol.31 , pp. 1-8
    • Bucher, J.R.1    Portier, C.J.2    Goodman, J.I.3    Faustman, E.M.4    Lucier, G.W.5
  • 11
    • 0023521213 scopus 로고
    • Association of persistent peroxisome proliferation and oxidative injury with hepatocarcinogenicity in female F-344 rats fed di(2-ethylhexyl)phthalate for two years
    • Cattley, R C., Conway, J. G., and Popp, J. A. (1987). Association of persistent peroxisome proliferation and oxidative injury with hepatocarcinogenicity in female F-344 rats fed di(2-ethylhexyl)phthalate for two years. Cancer Lett. 38, 15-22.
    • (1987) Cancer Lett. , vol.38 , pp. 15-22
    • Cattley, R.C.1    Conway, J.G.2    Popp, J.A.3
  • 12
    • 0011193527 scopus 로고
    • prepared by Hazelton Biotechnologies Co. (HBC Project No. 20989) and submitted to CMA
    • Chemical Manufacturers Association (CMA) (1986). Mouse lymphoma mutation assay: Final Report (June 1986), prepared by Hazelton Biotechnologies Co. (HBC Project No. 20989) and submitted to CMA.
    • (1986) Mouse Lymphoma Mutation Assay: Final Report (June 1986)
  • 13
    • 0000336139 scopus 로고
    • Regression models and life tables
    • Cox, D. (1972). Regression models and life tables. J. R. Stat. Soc. B 343, 187-220.
    • (1972) J. R. Stat. Soc. B , vol.343 , pp. 187-220
    • Cox, D.1
  • 14
    • 0000080398 scopus 로고
    • New tables for multiple comparisons with a control
    • Dunnett, C. (1964). New tables for multiple comparisons with a control. Biometrics 20, 482-491.
    • (1964) Biometrics , vol.20 , pp. 482-491
    • Dunnett, C.1
  • 15
    • 0001186657 scopus 로고
    • Disposition and metabolism of diisononyl phthalate (DINP) in fischer 344 rats: Single dosing studies
    • El-Hawari, M., Murill, E., Stoltz, M., Pallas, F., Lington, A. W., and Baldwin, J. K. (1985). Disposition and metabolism of diisononyl phthalate (DINP) in Fischer 344 rats: Single dosing studies. Toxicologist 5(1), 237.
    • (1985) Toxicologist , vol.5 , Issue.1 , pp. 237
    • El-Hawari, M.1    Murill, E.2    Stoltz, M.3    Pallas, F.4    Lington, A.W.5    Baldwin, J.K.6
  • 16
    • 0029967755 scopus 로고    scopus 로고
    • Chemicals associated with decreases in the incidence of mononuclear cell leukemia in the Fischer 344 rat
    • Elwell, M. E., Dunnick, J. K., Hailey, R. R., and Haseman, J. K. (1996). Chemicals associated with decreases in the incidence of mononuclear cell leukemia in the Fischer 344 rat. Toxicol. Pathol. 24, 239-245.
    • (1996) Toxicol. Pathol. , vol.24 , pp. 239-245
    • Elwell, M.E.1    Dunnick, J.K.2    Hailey, R.R.3    Haseman, J.K.4
  • 17
    • 0001806570 scopus 로고
    • Significance of naturally occurring tumors in evaluating the carcinogenicity of test compound: A review and an improved carcinogenicity bioassay for chemicals
    • Enomoto, M., Kobayashi, K., and Inoue, H. (1990). Significance of naturally occurring tumors in evaluating the carcinogenicity of test compound: A review and an improved carcinogenicity bioassay for chemicals. J. Toxicol. Pathol. 3(1), 1-17.
    • (1990) J. Toxicol. Pathol. , vol.3 , Issue.1 , pp. 1-17
    • Enomoto, M.1    Kobayashi, K.2    Inoue, H.3
  • 18
    • 0028142023 scopus 로고
    • Causes of death in rodent toxicity and carcinogenicity studies
    • Ettlin, R. A., Stirnmimann, P., and Prentice, D. E. (1994). Causes of death in rodent toxicity and carcinogenicity studies. Toxicol. Pathol. 22, 165-178.
    • (1994) Toxicol. Pathol. , vol.22 , pp. 165-178
    • Ettlin, R.A.1    Stirnmimann, P.2    Prentice, D.E.3
  • 24
    • 0018761565 scopus 로고
    • Statistical issues in interpretation of chronic bioassay for carcinogenicity
    • Gart, J., Chu, K., and Tarone, R. (1979). Statistical issues in interpretation of chronic bioassay for carcinogenicity. J. Natl. Cancer Inst. 62, 957-974.
    • (1979) J. Natl. Cancer Inst. , vol.62 , pp. 957-974
    • Gart, J.1    Chu, K.2    Tarone, R.3
  • 25
    • 0028141436 scopus 로고
    • Spontaneous tumor rates: Their uses to support rodent bioassays
    • Gopinath, C. (1994). Spontaneous tumor rates: Their uses to support rodent bioassays. Toxicol. Pathol. 22, 160-164.
    • (1994) Toxicol. Pathol. , vol.22 , pp. 160-164
    • Gopinath, C.1
  • 26
    • 0021647477 scopus 로고
    • Statistical issues in the design, analysis and interpretation of animal carcinogenicity studies
    • Haseman, J. (1984). Statistical issues in the design, analysis and interpretation of animal carcinogenicity studies. Environ. Health Perspect. 58, 385-392.
    • (1984) Environ. Health Perspect. , vol.58 , pp. 385-392
    • Haseman, J.1
  • 28
    • 0025284446 scopus 로고
    • Use of statistical decision rules for evaluating laboratory animal carcinogenicity studies
    • Haseman, J. K. (1990). Use of statistical decision rules for evaluating laboratory animal carcinogenicity studies. Fundam. Appl. Toxicol. 14, 637-648.
    • (1990) Fundam. Appl. Toxicol. , vol.14 , pp. 637-648
    • Haseman, J.K.1
  • 29
    • 0026728595 scopus 로고
    • Effects of corn oil, time-related changes and inter-laboratory variability on tumor occurrences in control Fischer 344 (F344/N) rats
    • Haseman, J. E., and Rao, G. N. (1992). Effects of corn oil, time-related changes and inter-laboratory variability on tumor occurrences in control Fischer 344 (F344/N) rats. Toxicol. Pathol. 20, 52-60.
    • (1992) Toxicol. Pathol. , vol.20 , pp. 52-60
    • Haseman, J.E.1    Rao, G.N.2
  • 31
    • 0025938503 scopus 로고
    • Chemicals associated with site specific neoplasia in 1394 long-term carcinogenesis experiments in laboratory rodents
    • Huff, J., Cervelo, J., Haseman, J. K., and Bucher, J. (1991). Chemicals associated with site specific neoplasia in 1394 long-term carcinogenesis experiments in laboratory rodents. Environ. Health Perspect. 93, 247-270.
    • (1991) Environ. Health Perspect. , vol.93 , pp. 247-270
    • Huff, J.1    Cervelo, J.2    Haseman, J.K.3    Bucher, J.4
  • 32
    • 0020958788 scopus 로고
    • Pathologist's responsibility in the diagnosis of oncogenesis
    • Iatriopoulos, M. J. (1983). Pathologist's responsibility in the diagnosis of oncogenesis. Toxicol. Pathol. 11, 132-140.
    • (1983) Toxicol. Pathol. , vol.11 , pp. 132-140
    • Iatriopoulos, M.J.1
  • 33
    • 33845382806 scopus 로고
    • Nonparametric estimation of incomplete observations
    • Kaplan, E., and Meier, P. (1958). Nonparametric estimation of incomplete observations. J. Am. Stat. Assoc. 53, 457-481.
    • (1958) J. Am. Stat. Assoc. , vol.53 , pp. 457-481
    • Kaplan, E.1    Meier, P.2
  • 34
    • 0015537760 scopus 로고
    • Studies on the toxicity of phthalates via ingestion
    • Krauskopf, L. G. (1973). Studies on the toxicity of phthalates via ingestion. Environ. Health Perspect. 3, 61-72.
    • (1973) Environ. Health Perspect. , vol.3 , pp. 61-72
    • Krauskopf, L.G.1
  • 35
    • 0001186657 scopus 로고
    • Disposition and metabolism of diisononyl phthalate (DINP) in Fischer 344 rats: Multiple dosing studies
    • Lington, A. W., Baldwin, J. K., Murril, E., Stoltz, M., Pallas, F., and El-Hawari, M. (1985). Disposition and metabolism of diisononyl phthalate (DINP) in Fischer 344 rats: Multiple dosing studies. Toxicologist 5(1), 238.
    • (1985) Toxicologist , vol.5 , Issue.1 , pp. 238
    • Lington, A.W.1    Baldwin, J.K.2    Murril, E.3    Stoltz, M.4    Pallas, F.5    El-Hawari, M.6
  • 36
    • 0011223971 scopus 로고
    • Short-term feeding studies assessing the testicular effects of nine plasticizers in the F344 rat
    • Lington, A. W., Gray, T. J. B., Evans, J., Lake, B., and Moran, B. (1993). Short-Term feeding studies assessing the testicular effects of nine plasticizers in the F344 rat. Acta Pharm. Toxicol. 73(Suppl. 11), 132.
    • (1993) Acta Pharm. Toxicol. , vol.73 , Issue.SUPPL. 11 , pp. 132
    • Lington, A.W.1    Gray, T.J.B.2    Evans, J.3    Lake, B.4    Moran, B.5
  • 37
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel, N., and Haenszel, W. (1959). Statistical aspects of the analysis of data from retrospective studies of disease. J. Natl. Cancer Inst. 22, 719-748.
    • (1959) J. Natl. Cancer Inst. , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 39
    • 0002563871 scopus 로고
    • Considerations in the evaluation and interpretation of long-term animal bioassays for carcinogenicity
    • (H. A. Millman and E. K. Weisburger, Eds.), Noyes Publications
    • Maronpot, R. R. (1985). Considerations in the evaluation and interpretation of long-term animal bioassays for carcinogenicity. In Handbook of Carcinogen Testing (H. A. Millman and E. K. Weisburger, Eds.), pp. 372-382. Noyes Publications.
    • (1985) Handbook of Carcinogen Testing , pp. 372-382
    • Maronpot, R.R.1
  • 40
    • 0022573516 scopus 로고
    • Guidelines for combining neoplasms for evaluation of rodent carcinogenesis studies
    • McConnell, E. E., Solleveld, H. A., Swenberg, J. A., and Boorman, G. A. (1986). Guidelines for combining neoplasms for evaluation of rodent carcinogenesis studies. J. Nat. Cancer Inst. 76, 283-289.
    • (1986) J. Nat. Cancer Inst. , vol.76 , pp. 283-289
    • McConnell, E.E.1    Solleveld, H.A.2    Swenberg, J.A.3    Boorman, G.A.4
  • 41
    • 0028609306 scopus 로고
    • Dichlorovos carcinogenicity: An assessment of the experimental evidence
    • Mennear, J. H. (1994). Dichlorovos carcinogenicity: An assessment of the experimental evidence. Reg. Toxicol. Pharmacol. 20, 354-361.
    • (1994) Reg. Toxicol. Pharmacol. , vol.20 , pp. 354-361
    • Mennear, J.H.1
  • 42
    • 85030295080 scopus 로고
    • Survey of plasticizer levels in food contact materials and in foods
    • Paper No. 21
    • Ministry of Agriculture Fisheries and Food (MAFF) (1987). Survey of plasticizer levels in food contact materials and in foods. Food surveillance, Paper No. 21, pp. 1-105.
    • (1987) Food Surveillance , pp. 1-105
  • 48
    • 0017008008 scopus 로고
    • Recent progress in safety evaluation studies on plasticizers and plastics and their controlled use in Japan
    • Omori, Y. (1976). Recent progress in safety evaluation studies on plasticizers and plastics and their controlled use in Japan. Environ. Health Perspect. 17, 203-209.
    • (1976) Environ. Health Perspect. , vol.17 , pp. 203-209
    • Omori, Y.1
  • 50
    • 0021992389 scopus 로고
    • Quantitative evaluation of hepatic foci of cellular alteration occurring spontaneously in Fischer 344 rats
    • Popp, J. A., Scortichini, B. H., and Garvey, L. K. (1985). Quantitative evaluation of hepatic foci of cellular alteration occurring spontaneously in Fischer 344 rats. Fundam. Appl. Toxicol. 5, 314-319.
    • (1985) Fundam. Appl. Toxicol. , vol.5 , pp. 314-319
    • Popp, J.A.1    Scortichini, B.H.2    Garvey, L.K.3
  • 51
    • 0021051308 scopus 로고
    • Carcinogenesis by hepatic peroxisome proliferators: Evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans
    • Reddy, J. K., and Lalwani, N. D. (1983). Carcinogenesis by hepatic peroxisome proliferators: Evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans. CRC Crit. Rev. Toxicol. 12, 1-58.
    • (1983) CRC Crit. Rev. Toxicol. , vol.12 , pp. 1-58
    • Reddy, J.K.1    Lalwani, N.D.2
  • 52
    • 0021246082 scopus 로고
    • The absence of testicular atrophy and in vivo and in vitro effects of hepatocyte morphology and peroxisomal enzyme activities in male rats following the administration of several alkanols
    • Rhodes, C., Soames, T., Stonard, M. D., Simpson, M. G., Vernall, A. J., and Elcombe, C. E. (1984). The absence of testicular atrophy and in vivo and in vitro effects of hepatocyte morphology and peroxisomal enzyme activities in male rats following the administration of several alkanols. Toxicol. Lett. 21, 103-109.
    • (1984) Toxicol. Lett. , vol.21 , pp. 103-109
    • Rhodes, C.1    Soames, T.2    Stonard, M.D.3    Simpson, M.G.4    Vernall, A.J.5    Elcombe, C.E.6
  • 54
    • 0020107041 scopus 로고
    • Tumors in control hamsters, rats, and mice: Literature tabulation
    • Sher, S. P. (1982). Tumors in control hamsters, rats, and mice: Literature tabulation. CRC Crit. Rev. Toxicol. 10, 49-79.
    • (1982) CRC Crit. Rev. Toxicol. , vol.10 , pp. 49-79
    • Sher, S.P.1
  • 56
    • 0021264752 scopus 로고
    • Natural history of body weight gains, survival, and neoplasia in the F344 rat
    • Solleveld, H. A., Haseman, J. K., and McConnell, E. E. (1984). Natural history of body weight gains, survival, and neoplasia in the F344 rat. J. Natl. Cancer Inst. 72, 929-940.
    • (1984) J. Natl. Cancer Inst. , vol.72 , pp. 929-940
    • Solleveld, H.A.1    Haseman, J.K.2    McConnell, E.E.3
  • 57
    • 0024955442 scopus 로고
    • The interpretation of equivocal or marginal animal carcinogenicity tests
    • Squire, R. A. (1989). The interpretation of equivocal or marginal animal carcinogenicity tests. Cell Biol. Toxicol. 5, 371-376.
    • (1989) Cell Biol. Toxicol. , vol.5 , pp. 371-376
    • Squire, R.A.1
  • 58
    • 0011241981 scopus 로고
    • Dermal disposition of di-isononyl phthalate (DINP) in Fischer 344 rats
    • Stoltz, M., El-Hawari, M., and Lington, A. W. (1985). Dermal disposition of di-isononyl phthalate (DINP) in Fischer 344 rats. Toxicologist 5(1), 246.
    • (1985) Toxicologist , vol.5 , Issue.1 , pp. 246
    • Stoltz, M.1    El-Hawari, M.2    Lington, A.W.3
  • 59
    • 0020852695 scopus 로고
    • Pathology of the mononuclear cell leukemia of Fischer 344 rats. I. Morphologic studies
    • Stromberg, P. C., and Vogtsberger, L. M. (1983a). Pathology of the mononuclear cell leukemia of Fischer 344 rats. I. Morphologic studies. Vet. Pathol. 20, 698-708.
    • (1983) Vet. Pathol. , vol.20 , pp. 698-708
    • Stromberg, P.C.1    Vogtsberger, L.M.2
  • 60
    • 0020854713 scopus 로고
    • Pathology of the mononuclear cell leukemia of Fischer 344 rats. III. Clinical chemistry
    • Stromberg, P. C., Vogtsberger, L. M., Marsh, L. R., and Wilson, F. D. (1983b). Pathology of the mononuclear cell leukemia of Fischer 344 rats. III. Clinical chemistry. Vet. Pathol. 20, 718-727.
    • (1983) Vet. Pathol. , vol.20 , pp. 718-727
    • Stromberg, P.C.1    Vogtsberger, L.M.2    Marsh, L.R.3    Wilson, F.D.4
  • 61
    • 0020852503 scopus 로고
    • Pathology of the mononuclear cell leukemia of Fischer 344 rats. II. Hematology
    • Stromberg, P. C., Vogtsberger, L. M., Marsh, L. R., and Wilson, F. D. (1983c). Pathology of the mononuclear cell leukemia of Fischer 344 rats. II. Hematology. Vet. Pathol. 20, 709-717.
    • (1983) Vet. Pathol. , vol.20 , pp. 709-717
    • Stromberg, P.C.1    Vogtsberger, L.M.2    Marsh, L.R.3    Wilson, F.D.4
  • 63
    • 0016759979 scopus 로고
    • Tests for trend in life table analysis
    • Tarone, R. E. (1975). Tests for trend in life table analysis. Biometrika 62, 679-682.
    • (1975) Biometrika , vol.62 , pp. 679-682
    • Tarone, R.E.1
  • 64
    • 0028355453 scopus 로고
    • Survival, body weight, and spontaneous neoplasms in ad libitum-fed food restricted Fischer 344 rats
    • Thurman, J. D., Bucci, T. J., Hart, R. W., and Turturro, A. (1994). Survival, body weight, and spontaneous neoplasms in ad libitum-fed food restricted Fischer 344 rats. Toxicol. Pathol. 23, 1-9.
    • (1994) Toxicol. Pathol. , vol.23 , pp. 1-9
    • Thurman, J.D.1    Bucci, T.J.2    Hart, R.W.3    Turturro, A.4
  • 65
    • 0028951382 scopus 로고
    • Analysis of studies related to tumorigenicity induced by hydroquinone
    • Whysner, J., Verna, L., English, J. C., and Williams, G. M. (1995). Analysis of studies related to tumorigenicity induced by hydroquinone. Reg. Toxicol. Pathol. 21, 158-176.
    • (1995) Reg. Toxicol. Pathol. , vol.21 , pp. 158-176
    • Whysner, J.1    Verna, L.2    English, J.C.3    Williams, G.M.4
  • 67
    • 0022390108 scopus 로고
    • Mutagenicity testing of di(2-ethylhexyl)phthalate and related chemicals in Salmonella
    • Zeiger, E., Haworth, S., Mortelmans, K., and Speck, W. (1985). Mutagenicity testing of di(2-ethylhexyl)phthalate and related chemicals in Salmonella. Environ. Mutagen. 7, 213-232.
    • (1985) Environ. Mutagen , vol.7 , pp. 213-232
    • Zeiger, E.1    Haworth, S.2    Mortelmans, K.3    Speck, W.4


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