Validation of transgenic mice carrying the human prototype c-Ha-ras gene as a bioassay model for rapid carcinogenicity testing

Environmental Health Perspectives

Volumn 106, Issue SUPPL. 1, 1998, Pages 57-69

  Yamamoto, Satoshi ^a,b,e   Urano, Koji ^b   Koizumi, Haruko ^b   Wakana, Shigeharu ^b   Hioki, Kyoji ^b   Mitsumori, Kunitoshi ^c   Kurokawa, Yuji ^c   Hayashi, Yuzo ^d   Nomura, Tatsuji ^b  

^a KEIO UNIVERSITY   (Japan)

^b CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS   (Japan)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^d KITASATO UNIVERSITY   (Japan)

^e BANYU PHARMACEUTICAL CO LTD   (Japan)

Author keywords

CB6F1 TgHras2 mouse; Chemical carcinogenesis; Human c Ha ras; RasH2 mouse; Short term carcinogenicity test; Transgenic mouse

Indexed keywords

CARCINOGEN; ENVIRONMENTAL MUTAGEN;

ANIMAL MODEL; BIOASSAY; CARCINOGEN TESTING; CARCINOGENESIS; FEMALE; INCIDENCE; MALE; MOUSE; NONHUMAN; ONCOGENE C H RAS; PRIORITY JOURNAL; PROBABILITY; REVIEW; TRANSGENIC MOUSE;

EID: 0031977910     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.98106s157     Document Type: Review

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