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Volumn 24, Issue 6, 1996, Pages 757-768

The effects of diet, ad libitum overfeeding, and moderate dietary restriction on the rodent bioassay: The uncontrolled variable in safety assessment

Author keywords

bioassay sensitivity; diet and cancer; diet and oxidative stress; diet and reproductive senescence; diet and toxicity; obesity; Overnutrition

Indexed keywords

ANIMAL EXPERIMENT; BIOASSAY; CONFERENCE PAPER; DIET RESTRICTION; FEMALE; MALE; NONHUMAN; OBESITY; OVERNUTRITION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RISK ASSESSMENT;

EID: 0030451167     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/019262339602400620     Document Type: Conference Paper
Times cited : (99)

References (49)
  • 2
    • 0037892114 scopus 로고
    • Tissue levels of 8-hydroxydeoxyguanosine (8-OHdG) in Sprague-Dawley rats fed ad libitum or fed a calorie-restricted diet
    • Adams SP, Laws GM, Alberts DW, Storer RD, and Keenan KP (1995). Tissue levels of 8-hydroxydeoxyguanosine (8-OHdG) in Sprague-Dawley rats fed ad libitum or fed a calorie-restricted diet. Fund. Appl. Toxicol. 15(1): 279.
    • (1995) Fund. Appl. Toxicol. , vol.15 , Issue.1 , pp. 279
    • Adams, S.P.1    Laws, G.M.2    Alberts, D.W.3    Storer, R.D.4    Keenan, K.P.5
  • 3
    • 0023193072 scopus 로고
    • Caloric intake, body weight, and cancer: A review
    • Albanes D (1987). Caloric intake, body weight, and cancer: A review Nutr. Cancer 9: 199-217
    • (1987) Nutr. Cancer , vol.9 , pp. 199-217
    • Albanes, D.1
  • 5
    • 0022486738 scopus 로고
    • What is there that is not poison? A study of the Third Defense by Paracelsus
    • Deichmann WB, Henschler D, Holmstedt B, and Keil G (1986). What is there that is not poison? A study of the Third Defense by Paracelsus. Arch. Toxicol. 58: 207-213.
    • (1986) Arch. Toxicol. , vol.58 , pp. 207-213
    • Deichmann, W.B.1    Henschler, D.2    Holmstedt, B.3    Keil, G.4
  • 6
    • 7344230760 scopus 로고
    • Effects of moderate dietary restriction (MDR) on toxicity and toxicokinetic (TK) profiles of non-genotoxic pharmaceuticals in rats
    • Dixit R, Keenan KP, Patrick D, Huber AC, Robyak K and Zacchei A (1995). Effects of moderate dietary restriction (MDR) on toxicity and toxicokinetic (TK) profiles of non-genotoxic pharmaceuticals in rats. Fund. Appl. Toxicol. 15(1): 32.
    • (1995) Fund. Appl. Toxicol. , vol.15 , Issue.1 , pp. 32
    • Dixit, R.1    Keenan, K.P.2    Patrick, D.3    Huber, A.C.4    Robyak, K.5    Zacchei, A.6
  • 7
    • 74049101016 scopus 로고    scopus 로고
    • Modulation of carcinogenesis bioassay dose selection by moderate dietary restriction (MDR) in rats: Relationship with cytochrome P450 (CYP) levels, enzyme activities and toxicokinetics (TK)
    • Dixit R, Keenan K, Umbenhauer D, DeLuca J, Morrissey R, Coleman J, and Thomas J (1996). Modulation of carcinogenesis bioassay dose selection by moderate dietary restriction (MDR) in rats: Relationship with cytochrome P450 (CYP) levels, enzyme activities and toxicokinetics (TK). Fund. Appl. Toxicol. 30(1): 203.
    • (1996) Fund. Appl. Toxicol. , vol.30 , Issue.1 , pp. 203
    • Dixit, R.1    Keenan, K.2    Umbenhauer, D.3    DeLuca, J.4    Morrissey, R.5    Coleman, J.6    Thomas, J.7
  • 8
    • 0024601636 scopus 로고
    • Effect of chronic restriction on physiological variables related to energy metabolism in the male Fischer 344 rat
    • Duffy PH, Feuers RJ, Leakey JA, Nakamura KD, Turtuorro A, and Hart RW (1989) Effect of chronic restriction on physiological variables related to energy metabolism in the male Fischer 344 rat. Mech. Aging Dev. 48: 117-133
    • (1989) Mech. Aging Dev. , vol.48 , pp. 117-133
    • Duffy, P.H.1    Feuers, R.J.2    Leakey, J.A.3    Nakamura, K.D.4    Turtuorro, A.5    Hart, R.W.6
  • 11
    • 0027721161 scopus 로고
    • The early effects of dietary restriction on the pathogenesis of chronic renal disease in Sprague-Dawley rats at 12 months
    • Gumprecht LA, Long CR, Soper KA, Smith PF, Hascheck-Hock WM, and Keenan KP (1993) The early effects of dietary restriction on the pathogenesis of chronic renal disease in Sprague-Dawley rats at 12 months. Toxicol. Pathol. 21(6): 528-537.
    • (1993) Toxicol. Pathol. , vol.21 , Issue.6 , pp. 528-537
    • Gumprecht, L.A.1    Long, C.R.2    Soper, K.A.3    Smith, P.F.4    Hascheck-Hock, W.M.5    Keenan, K.P.6
  • 14
    • 0026728595 scopus 로고
    • Effects of corn-oil, time-related changes and inter-laboratory variability on tumor occurrence in control Fisher 344 (F-344/N) rats
    • Haseman JK and Rao GR (1992). Effects of corn-oil, time-related changes and inter-laboratory variability on tumor occurrence in control Fisher 344 (F-344/N) rats. Toxical. Pathol. 20(1): 52-60.
    • (1992) Toxical. Pathol. , vol.20 , Issue.1 , pp. 52-60
    • Haseman, J.K.1    Rao, G.R.2
  • 15
    • 0023838776 scopus 로고
    • The influence of dietary protein source on longevity and age-related disease processes of Fischer rats
    • Iwasaki K, Gleiser CA, Masoro EJ, McMahan CA, Seo EJ, and Yu BP (1988). The influence of dietary protein source on longevity and age-related disease processes of Fischer rats. J. Gerontol. 43: B5-12.
    • (1988) J. Gerontol. , vol.43
    • Iwasaki, K.1    Gleiser, C.A.2    Masoro, E.J.3    McMahan, C.A.4    Seo, E.J.5    Yu, B.P.6
  • 16
  • 17
    • 0002012555 scopus 로고
    • The effect of diet and dietary optimization (caloric restriction) on rat survival in carcinogenicity studies-an industrial viewpoint
    • JAN McAuslane, CF Lumley, and SR Walker (eds). Butler and Tanner, London
    • Keenan KP, Smith PF, Ballam GC, Soper KA. and Bokelman DL (1992). The effect of diet and dietary optimization (caloric restriction) on rat survival in carcinogenicity studies-an industrial viewpoint. In: Centre for Medicines Research Workshop. The Carcinogenicity Debate JAN McAuslane, CF Lumley, and SR Walker (eds). Butler and Tanner, London, pp. 77-102.
    • (1992) Centre for Medicines Research Workshop. The Carcinogenicity Debate , pp. 77-102
    • Keenan, K.P.1    Smith, P.F.2    Ballam, G.C.3    Soper, K.A.4    Bokelman, D.L.5
  • 18
    • 0028037628 scopus 로고
    • The effects of overfeeding and dietary restriction on Sprague-Dawley rat survival and early pathology biomarkers of aging
    • Keenan KP, Smith PF, Hertzog P, Soper KA, Ballam GG, and Clark RL (1994). The effects of overfeeding and dietary restriction on Sprague-Dawley rat survival and early pathology biomarkers of aging. Taxicol. Pathol 22(3): 300-315.
    • (1994) Taxicol. Pathol , vol.22 , Issue.3 , pp. 300-315
    • Keenan, K.P.1    Smith, P.F.2    Hertzog, P.3    Soper, K.A.4    Ballam, G.G.5    Clark, R.L.6
  • 19
    • 0000221346 scopus 로고
    • The effects of dietary (caloric) restriction on rat aging, survival, pathology and toxicology
    • U Mohr, DL Dungworth, and CC Capen (eds). ILSI Press, Washington, D.C.
    • Keenan KP, Smith PF, and Soper KA (1994). The effects of dietary (caloric) restriction on rat aging, survival, pathology and toxicology. In: Pathobiology of the Aging Rat, Vol. II, U Mohr, DL Dungworth, and CC Capen (eds). ILSI Press, Washington, D.C., pp. 609-628.
    • (1994) Pathobiology of the Aging Rat , vol.2 , pp. 609-628
    • Keenan, K.P.1    Smith, P.F.2    Soper, K.A.3
  • 20
    • 0002305284 scopus 로고
    • The effects of ad libitum overfeeding and moderate dietary restriction on Sprague-Dawley rat survival, spontaneous carcinogenesis, chronic disease, and the toxicologic response to pharmaceuticals
    • RW Hart, DA Neumann, and R Robertson (eds). ILSI Press, Washington, D.C.
    • Keenan KP and Soper KA (1995). The effects of ad libitum overfeeding and moderate dietary restriction on Sprague-Dawley rat survival, spontaneous carcinogenesis, chronic disease, and the toxicologic response to pharmaceuticals. In: Dietary Restriction: Implications for the Design and Interpretation of Toxicity and Carcinogenicity Studies, RW Hart, DA Neumann, and R Robertson (eds). ILSI Press, Washington, D.C., pp. 99-126.
    • (1995) Dietary Restriction: Implications for the Design and Interpretation of Toxicity and Carcinogenicity Studies , pp. 99-126
    • Keenan, K.P.1    Soper, K.A.2
  • 21
    • 0029005868 scopus 로고
    • Diet, overfeeding and moderate dietary restriction in control Sprague-Dawley rats. II. Effects on age-related proliferative and degenerative lesions
    • Keenan KP, Soper KA, Hertzog PR, Gumprecht LA, Smith PF, Mattson BA, Ballam GC, and Clark RL (1995). Diet, overfeeding and moderate dietary restriction in control Sprague-Dawley rats. II. Effects on age-related proliferative and degenerative lesions. Toxicol. Pathol 23(3): 287-302.
    • (1995) Toxicol. Pathol , vol.23 , Issue.3 , pp. 287-302
    • Keenan, K.P.1    Soper, K.A.2    Hertzog, P.R.3    Gumprecht, L.A.4    Smith, P.F.5    Mattson, B.A.6    Ballam, G.C.7    Clark, R.L.8
  • 22
    • 0029038434 scopus 로고
    • Diet, overfeeding and moderate dietary restriction in control Sprague-Dawley rats: I. Effects on spontaneous neoplasms
    • Keenan KP, Soper KA, Smith PF, Ballam GC and Clark RL (1995). Diet, overfeeding and moderate dietary restriction in control Sprague-Dawley rats: I. Effects on spontaneous neoplasms Toxicol. Pathol. 23(3): 269-286.
    • (1995) Toxicol. Pathol. , vol.23 , Issue.3 , pp. 269-286
    • Keenan, K.P.1    Soper, K.A.2    Smith, P.F.3    Ballam, G.C.4    Clark, R.L.5
  • 23
    • 0024580989 scopus 로고
    • Determination of degree of energy restriction necessary to reduce DMBA-induced mammary tumorigenesis in rats during the promotion phase
    • Klurfeld DM, Welch CB, Davis MJ, and Kritchevsky D (1989). Determination of degree of energy restriction necessary to reduce DMBA-induced mammary tumorigenesis in rats during the promotion phase. J. Nutr. 119: 286-291.
    • (1989) J. Nutr. , vol.119 , pp. 286-291
    • Klurfeld, D.M.1    Welch, C.B.2    Davis, M.J.3    Kritchevsky, D.4
  • 24
    • 38249007381 scopus 로고
    • Energy restriction and carcinogenesis
    • Kritchevsky D (1993). Energy restriction and carcinogenesis. Food Res. Intl. 26: 289-295
    • (1993) Food Res. Intl. , vol.26 , pp. 289-295
    • Kritchevsky, D.1
  • 25
    • 0001116876 scopus 로고
    • Changes in life span of research animals, leading to questions about validity of toxicologic studies
    • Lang PL (1991). Changes in life span of research animals, leading to questions about validity of toxicologic studies. Chem. Reg. Rep. 14: 1518-1520.
    • (1991) Chem. Reg. Rep. , vol.14 , pp. 1518-1520
    • Lang, P.L.1
  • 26
    • 74049155093 scopus 로고    scopus 로고
    • Effect of initial body weight and moderate dietary restriction on survival in Sprague-Dawley (SD) rats
    • Laroque P, Keenan K, Soper K, Dorian C, Hubert M-F. and Duprat P (1996) Effect of initial body weight and moderate dietary restriction on survival in Sprague-Dawley (SD) rats. Fund. Appl. Taxicol. 30(1): 206.
    • (1996) Fund. Appl. Taxicol. , vol.30 , Issue.1 , pp. 206
    • Laroque, P.1    Keenan, K.2    Soper, K.3    Dorian, C.4    Hubert, M.-F.5    Duprat, P.6
  • 29
  • 30
    • 0024340303 scopus 로고
    • Dietary modulation of the progression of nephropathy in aging rats: An evaluation of the importance of protein
    • Masoro EJ, Iwasaki K, Gleiser CA, McMahan CA, Seo EJ, and Yu BP (1989). Dietary modulation of the progression of nephropathy in aging rats: An evaluation of the importance of protein Am. J. Clin. Nutr. 49: 1217-1227
    • (1989) Am. J. Clin. Nutr. , vol.49 , pp. 1217-1227
    • Masoro, E.J.1    Iwasaki, K.2    Gleiser, C.A.3    McMahan, C.A.4    Seo, E.J.5    Yu, B.P.6
  • 31
    • 0024585280 scopus 로고
    • Evidence for the glycation hypothesis of aging from the food-restricted rodent model
    • Masoro EJ, Katz MS, and McMahan CA (1989). Evidence for the glycation hypothesis of aging from the food-restricted rodent model. J. Gerontol. 44: B20-22.
    • (1989) J. Gerontol. , vol.44
    • Masoro, E.J.1    Katz, M.S.2    McMahan, C.A.3
  • 32
    • 0025788814 scopus 로고
    • Aging as a consequence of fuel utilization
    • Masoro EJ and McCarter RJM (1991). Aging as a consequence of fuel utilization. Aging 3: 117-128.
    • (1991) Aging , vol.3 , pp. 117-128
    • Masoro, E.J.1    McCarter, R.J.M.2
  • 34
    • 0026398216 scopus 로고
    • Retardation of the aging process in rats by food restriction
    • Masoro EJ, Shimokawa I, and Yu BP (1991). Retardation of the aging process in rats by food restriction. Ann. N. Y. Acad Sci 621: 337-352.
    • (1991) Ann. N. Y. Acad Sci , vol.621 , pp. 337-352
    • Masoro, E.J.1    Shimokawa, I.2    Yu, B.P.3
  • 35
    • 0002458132 scopus 로고
    • The effect of retarded growth upon the length of the life span and upon the ultimate size
    • McCay C, Crowell M. and Maynard L (1935). The effect of retarded growth upon the length of the life span and upon the ultimate size. J. Nutr: 10: 63-79.
    • (1935) J. Nutr , vol.10 , pp. 63-79
    • McCay, C.1    Crowell, M.2    Maynard, L.3
  • 36
    • 0027360855 scopus 로고
    • Actual causes of death in the United States
    • McGinnis JM and Foege WH (1993). Actual causes of death in the United States. J. Am Med. Assoc. 270(18): 2207-2212.
    • (1993) J. Am Med. Assoc. , vol.270 , Issue.18 , pp. 2207-2212
    • McGinnis, J.M.1    Foege, W.H.2
  • 38
    • 0003335338 scopus 로고
    • Nutrient requirements of the laboratory rat
    • National Academy Press, Washington, D.C.
    • National Research Council, Subcommittee of Laboratory Animal Nutrition (1995). Nutrient requirements of the laboratory rat. In Nutrient Requirements of Laboratory Animals, 4th rev. ed. National Academy Press, Washington, D.C., pp. 11-79
    • (1995) Nutrient Requirements of Laboratory Animals, 4th Rev. Ed. , pp. 11-79
  • 39
    • 0021839242 scopus 로고
    • Tumongenic effects of directand indirect-acting chemical carcinogens in rats on a restricted diet
    • Pollard M and Luckert PH (1985). Tumongenic effects of directand indirect-acting chemical carcinogens in rats on a restricted diet J. Natl Cancer Inst. 74: 1347-1349.
    • (1985) J. Natl Cancer Inst. , vol.74 , pp. 1347-1349
    • Pollard, M.1    Luckert, P.H.2
  • 40
    • 0025375972 scopus 로고
    • Growth, body weight, survival, and tumor trends in F-344/ N rats during an eleven-year period
    • Rao GN, Hasemen JK, Grumbein S, Crawford DD, and Eustis SL (1990). Growth, body weight, survival, and tumor trends in F-344/ N rats during an eleven-year period. Toxicol. Pathol. 18(1): 61-70
    • (1990) Toxicol. Pathol. , vol.18 , Issue.1 , pp. 61-70
    • Rao, G.N.1    Hasemen, J.K.2    Grumbein, S.3    Crawford, D.D.4    Eustis, S.L.5
  • 41
    • 0028219794 scopus 로고
    • Historical histopathological control data for laboratory rodents: Valuable treasure or worthless trash?
    • Roe FJC (1994). Historical histopathological control data for laboratory rodents: Valuable treasure or worthless trash? Lab. Anim 28: 148-154.
    • (1994) Lab. Anim , vol.28 , pp. 148-154
    • Roe, F.J.C.1
  • 42
    • 0028986103 scopus 로고
    • The Biosure Study: Influence of composition of diet and food consumption on longevity, degenerative disease and neoplasia in Wistar rats studies for up to 30 months post weaning
    • Roe FJC, Lee PN, Conybeare G, Kelly D, Matter B, Prentice D. and Tobin G (1995). The Biosure Study: Influence of composition of diet and food consumption on longevity, degenerative disease and neoplasia in Wistar rats studies for up to 30 months post weaning. Food Chem. Toxicol. 33(suppl 1): 1S-100S.
    • (1995) Food Chem. Toxicol. , vol.33 , Issue.1 SUPPL.
    • Roe, F.J.C.1    Lee, P.N.2    Conybeare, G.3    Kelly, D.4    Matter, B.5    Prentice, D.6    Tobin, G.7
  • 45
    • 0002452849 scopus 로고
    • Nutrition and longevity in experimental animals
    • Winick M (ed). J. Wiley and Sons, New York
    • Ross M (1976). Nutrition and longevity in experimental animals. In: Nutrition and Aging, Winick M (ed). J. Wiley and Sons, New York, pp. 23-41.
    • (1976) Nutrition and Aging , pp. 23-41
    • Ross, M.1
  • 46
    • 0030038103 scopus 로고    scopus 로고
    • Oxidative stress, caloric restriction, and aging
    • Sohal RS and Weindruch R (1996). Oxidative stress, caloric restriction, and aging. Science 273(5271): 59-63.
    • (1996) Science , vol.273 , Issue.5271 , pp. 59-63
    • Sohal, R.S.1    Weindruch, R.2


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