-
1
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144: 646–674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
84925969707
-
Metabolic pathways promoting cancer cell survival and growth
-
Boroughs LK, DeBerardinis RJ. Metabolic pathways promoting cancer cell survival and growth. Nat Cell Biol 2015; 17: 351–359.
-
(2015)
Nat Cell Biol
, vol.17
, pp. 351-359
-
-
Boroughs, L.K.1
Deberardinis, R.J.2
-
3
-
-
84948085766
-
Oncogenes strike a balance between cellular growth and homeostasis
-
Qiu B, Simon MC. Oncogenes strike a balance between cellular growth and homeostasis. Semin Cell Dev Biol 2015; 43: 3–10.
-
(2015)
Semin Cell Dev Biol
, vol.43
, pp. 3-10
-
-
Qiu, B.1
Simon, M.C.2
-
4
-
-
12444279265
-
On the origin of cancer cells
-
Warburg O. On the origin of cancer cells. Science 1956; 123: 309–314.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
5
-
-
84860321700
-
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism
-
Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E et al. Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell 2012; 149: 656–670.
-
(2012)
Cell
, vol.149
, pp. 656-670
-
-
Ying, H.1
Kimmelman, A.C.2
Lyssiotis, C.A.3
Hua, S.4
Chu, G.C.5
Fletcher-Sananikone, E.6
-
6
-
-
80051866908
-
Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth
-
Gaglio D, Metallo CM, Gameiro PA, Hiller K, Danna LS, Balestrieri C et al. Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth. Mol Syst Biol 2011; 7: 523.
-
(2011)
Mol Syst Biol
, vol.7
, pp. 523
-
-
Gaglio, D.1
Metallo, C.M.2
Gameiro, P.A.3
Hiller, K.4
Danna, L.S.5
Balestrieri, C.6
-
7
-
-
84875894714
-
Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
-
Son J, Lyssiotis CA, Ying H, Wang X, Hua S, Ligorio M et al. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. Nature 2013; 496: 101–105.
-
(2013)
Nature
, vol.496
, pp. 101-105
-
-
Son, J.1
Lyssiotis, C.A.2
Ying, H.3
Wang, X.4
Hua, S.5
Ligorio, M.6
-
8
-
-
84888866083
-
Hooked on fat: The role of lipid synthesis in cancer metabolism and tumour development
-
Baenke F, Peck B, Miess H, Schulze A. Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development. Dis Model Mech 2013; 6: 1353–1363.
-
(2013)
Dis Model Mech
, vol.6
, pp. 1353-1363
-
-
Baenke, F.1
Peck, B.2
Miess, H.3
Schulze, A.4
-
9
-
-
84904732950
-
Hypoxia, lipids, and cancer: Surviving the harsh tumor microenvironment
-
Ackerman D, Simon MC. Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment. Trends Cell Biol 2014; 24: 472–478.
-
(2014)
Trends Cell Biol
, vol.24
, pp. 472-478
-
-
Ackerman, D.1
Simon, M.C.2
-
10
-
-
84885355517
-
The role of cholesterol metabolism and cholesterol transport in carcinogenesis: A review of scientific findings, relevant to future cancer therapeutics
-
Cruz PM, Mo H, McConathy WJ, Sabnis N, Lacko AG. The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings, relevant to future cancer therapeutics. Front Pharmacol 2013; 4: 119.
-
(2013)
Front Pharmacol
, vol.4
, pp. 119
-
-
Cruz, P.M.1
Mo, H.2
McConathy, W.J.3
Sabnis, N.4
Lacko, A.G.5
-
11
-
-
84980050613
-
HIF2alphadependent lipid storage promotes endoplasmic reticulum homeostasis in clearcell renal cell carcinoma
-
Qiu B, Ackerman D, Sanchez DJ, Li B, Ochocki JD, Grazioli et al. HIF2alphadependent lipid storage promotes endoplasmic reticulum homeostasis in clearcell renal cell carcinoma. Cancer Discov 2015; 5: 652–667.
-
(2015)
Cancer Discov
, vol.5
, pp. 652-667
-
-
Qiu, B.1
Ackerman, D.2
Sanchez, D.J.3
Li, B.4
Ochockigrazioli, J.D.5
-
12
-
-
40949096164
-
Lipid bodies are reservoirs of cyclooxygenase-2 and sites of prostaglandinE2 synthesis in colon cancer cells
-
Accioly MT, Pacheco P, Maya-Monteiro CM, Carrossini N, Robbs BK, Oliveira SS et al. Lipid bodies are reservoirs of cyclooxygenase-2 and sites of prostaglandinE2 synthesis in colon cancer cells. Cancer Res 2008; 68: 1732–1740.
-
(2008)
Cancer Res
, vol.68
, pp. 1732-1740
-
-
Accioly, M.T.1
Pacheco, P.2
Maya-Monteiro, C.M.3
Carrossini, N.4
Robbs, B.K.5
Oliveira, S.S.6
-
13
-
-
84895741045
-
Cholesteryl ester accumulation induced by PTEN loss and PI3K/AKT activation underlies human prostate cancer aggressiveness
-
Yue S, Li J, Lee SY, Lee HJ, Shao T, Song B et al. Cholesteryl ester accumulation induced by PTEN loss and PI3K/AKT activation underlies human prostate cancer aggressiveness. Cell Metab 2014; 19: 393–406.
-
(2014)
Cell Metab
, vol.19
, pp. 393-406
-
-
Yue, S.1
Li, J.2
Lee, S.Y.3
Lee, H.J.4
Shao, T.5
Song, B.6
-
14
-
-
84923673721
-
Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma
-
Guillaumond F, Bidaut G, Ouaissi M, Servais S, Gouirand V, Olivares O et al. Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma. Proc Natl Acad Sci USA 2015; 112: 2473–2478.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. 2473-2478
-
-
Guillaumond, F.1
Bidaut, G.2
Ouaissi, M.3
Servais, S.4
Gouirand, V.5
Olivares, O.6
-
16
-
-
85019264288
-
Intratumor cholesteryl ester accumulation is associated with human breast cancer proliferation and aggressive potential: A molecular and clinicopathological study
-
de Gonzalo-Calvo D, Lopez-Vilaro L, Nasarre L, Perez-Olabarria M, Vazquez T, Escuin D et al. Intratumor cholesteryl ester accumulation is associated with human breast cancer proliferation and aggressive potential: a molecular and clinicopathological study. BMC Cancer 2015; 15: 460.
-
(2015)
BMC Cancer
, vol.15
-
-
de Gonzalo-Calvo, D.1
Lopez-Vilaro, L.2
Nasarre, L.3
Perez-Olabarria, M.4
Vazquez, T.5
Escuin, D.6
-
17
-
-
84925307884
-
The role of lipid droplets and adipocytes in cancer. Raman imaging of cell cultures: MCF10A, MCF7, and MDA-MB-231 compared to adipocytes in cancerous human breast tissue
-
Abramczyk H, Surmacki J, Kopec M, Olejnik AK, Lubecka-Pietruszewska K, Fabianowska-Majewska K. The role of lipid droplets and adipocytes in cancer. Raman imaging of cell cultures: MCF10A, MCF7, and MDA-MB-231 compared to adipocytes in cancerous human breast tissue. Analyst 2015; 140: 2224–2235.
-
(2015)
Analyst
, vol.140
, pp. 2224-2235
-
-
Abramczyk, H.1
Surmacki, J.2
Kopec, M.3
Olejnik, A.K.4
Lubecka-Pietruszewska, K.5
Fabianowska-Majewska, K.6
-
18
-
-
84919429576
-
Lipid droplets: A new player in colorectal cancer stem cells unveiled by spectroscopic imaging
-
Tirinato L, Liberale C, Di Franco S, Candeloro P, Benfante A, La Rocca R et al. Lipid droplets: a new player in colorectal cancer stem cells unveiled by spectroscopic imaging. Stem Cells 2015; 33: 35–44.
-
(2015)
Stem Cells
, vol.33
, pp. 35-44
-
-
Tirinato, L.1
Liberale, C.2
Di Franco, S.3
Candeloro, P.4
Benfante, A.5
la Rocca, R.6
-
19
-
-
84937687778
-
Label-free Raman spectroscopic imaging monitors the integral physiologically relevant drug responses in cancer cells
-
El-Mashtoly SF, Yosef HK, Petersen D, Mavarani L, Maghnouj A, Hahn S et al. Label-free Raman spectroscopic imaging monitors the integral physiologically relevant drug responses in cancer cells. Anal Chem 2015; 87: 7297–7304.
-
(2015)
Anal Chem
, vol.87
, pp. 7297-7304
-
-
El-Mashtoly, S.F.1
Yosef, H.K.2
Petersen, D.3
Mavarani, L.4
Maghnouj, A.5
Hahn, S.6
-
20
-
-
84938958194
-
CARS based label-free assay for assessment of drugs by monitoring lipid droplets in tumour cells
-
Steuwe C, Patel II, Ul-Hasan M, Schreiner A, Boren J, Brindle KM et al. CARS based label-free assay for assessment of drugs by monitoring lipid droplets in tumour cells. J Biophotonics 2014; 7: 906–913.
-
(2014)
J Biophotonics
, vol.7
, pp. 906-913
-
-
Steuwe, C.1
Patel, I.I.2
Ul-Hasan, M.3
Schreiner, A.4
Boren, J.5
Brindle, K.M.6
-
21
-
-
84926625473
-
Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a lowlipid environment
-
Daniels VW, Smans K, Royaux I, Chypre M, Swinnen JV, Zaidi N. Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a lowlipid environment. PLoS One 2014; 9: e106913.
-
(2014)
Plos One
, vol.9
-
-
Daniels, V.W.1
Smans, K.2
Royaux, I.3
Chypre, M.4
Swinnen, J.V.5
Zaidi, N.6
-
22
-
-
84878464291
-
Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids
-
Kamphorst JJ, Cross JR, Fan J, de Stanchina E, Mathew R, White EP et al. Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids. Proc Natl Acad Sci USA 2013; 110: 8882–8887.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 8882-8887
-
-
Kamphorst, J.J.1
Cross, J.R.2
Fan, J.3
de Stanchina, E.4
Mathew, R.5
White, E.P.6
-
23
-
-
84936951083
-
Saturated and mono-unsaturated lysophosphatidylcholine metabolism in tumour cells: A potential therapeutic target for preventing metastases
-
Raynor A, Jantscheff P, Ross T, Schlesinger M, Wilde M, Haasis S et al. Saturated and mono-unsaturated lysophosphatidylcholine metabolism in tumour cells: a potential therapeutic target for preventing metastases. Lipids Health Dis 2015; 14: 69.
-
(2015)
Lipids Health Dis
, vol.14
-
-
Raynor, A.1
Jantscheff, P.2
Ross, T.3
Schlesinger, M.4
Wilde, M.5
Haasis, S.6
-
24
-
-
77950546594
-
Dominant uptake of fatty acid over glucose by prostate cells: A potential new diagnostic and therapeutic approach
-
Liu Y, Zuckier LS, Ghesani NV. Dominant uptake of fatty acid over glucose by prostate cells: a potential new diagnostic and therapeutic approach. Anticancer Res 2010; 30: 369–374.
-
(2010)
Anticancer Res
, vol.30
, pp. 369-374
-
-
Liu, Y.1
Zuckier, L.S.2
Ghesani, N.V.3
-
25
-
-
84867595989
-
Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma
-
Caro P, Kishan AU, Norberg E, Stanley IA, Chapuy B, Ficarro SB et al. Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma. Cancer Cell 2012; 22: 547–560.
-
(2012)
Cancer Cell
, vol.22
, pp. 547-560
-
-
Caro, P.1
Kishan, A.U.2
Norberg, E.3
Stanley, I.A.4
Chapuy, B.5
Ficarro, S.B.6
-
26
-
-
84919390715
-
Direct visualization of de novo lipogenesis in single living cells
-
Li J, Cheng JX. Direct visualization of de novo lipogenesis in single living cells. Sci Rep 2014; 4: 6807.
-
(2014)
Sci Rep
, vol.4
, pp. 6807
-
-
Li, J.1
Cheng, J.X.2
-
27
-
-
78049307002
-
De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation
-
Rysman E, Brusselmans K, Scheys K, Timmermans L, Derua R, Munck S et al. De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation. Cancer Res 2010; 70: 8117–8126.
-
(2010)
Cancer Res
, vol.70
, pp. 8117-8126
-
-
Rysman, E.1
Brusselmans, K.2
Scheys, K.3
Timmermans, L.4
Derua, R.5
Munck, S.6
-
28
-
-
79955073961
-
Lipid rafts: Signaling and sorting platforms of cells and their roles in cancer
-
Staubach S, Hanisch FG. Lipid rafts: signaling and sorting platforms of cells and their roles in cancer. Expert Rev Proteomics 2011; 8: 263–277.
-
(2011)
Expert Rev Proteomics
, vol.8
, pp. 263-277
-
-
Staubach, S.1
Hanisch, F.G.2
-
29
-
-
84883455835
-
Targeting the sphingosine-1 phosphate axis in cancer, inflammation and beyond
-
Kunkel GT, Maceyka M, Milstien S, Spiegel S. Targeting the sphingosine-1 phosphate axis in cancer, inflammation and beyond. Nat Rev Drug Discov 2013; 12: 688–702.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 688-702
-
-
Kunkel, G.T.1
Maceyka, M.2
Milstien, S.3
Spiegel, S.4
-
30
-
-
77649179672
-
Eicosanoids and cancer
-
Wang D, Dubois RN. Eicosanoids and cancer. Nat Rev Cancer 2010; 10: 181–193.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 181-193
-
-
Wang, D.1
Dubois, R.N.2
-
31
-
-
84874105185
-
Multifaceted roles of PGE2 in inflammation and cancer
-
Nakanishi M, Rosenberg DW. Multifaceted roles of PGE2 in inflammation and cancer. Semin Immunopathol 2013; 35: 123–137.
-
(2013)
Semin Immunopathol
, vol.35
, pp. 123-137
-
-
Nakanishi, M.1
Rosenberg, D.W.2
-
32
-
-
34748912615
-
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
-
Menendez JA, Lupu R. Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Nat Rev Cancer 2007; 7: 763–777.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 763-777
-
-
Menendez, J.A.1
Lupu, R.2
-
33
-
-
84864858864
-
ATP-citrate lyase: A key player in cancer metabolism
-
Zaidi N, Swinnen JV, Smans K. ATP-citrate lyase: a key player in cancer metabolism. Cancer Res 2012; 72: 3709–3714.
-
(2012)
Cancer Res
, vol.72
, pp. 3709-3714
-
-
Zaidi, N.1
Swinnen, J.V.2
Smans, K.3
-
34
-
-
33745728461
-
Fatty acid synthase and cancer: New application of an old pathway
-
Kuhajda FP. Fatty acid synthase and cancer: new application of an old pathway. Cancer Res 2006; 66: 5977–5980.
-
(2006)
Cancer Res
, vol.66
, pp. 5977-5980
-
-
Kuhajda, F.P.1
-
35
-
-
84868000180
-
Non-glucose metabolism in cancer cells--is it all in the fat?
-
Biswas S, Lunec J, Bartlett K. Non-glucose metabolism in cancer cells--is it all in the fat? Cancer Metastasis Rev 2012; 31: 689–698.
-
(2012)
Cancer Metastasis Rev
, vol.31
, pp. 689-698
-
-
Biswas, S.1
Lunec, J.2
Bartlett, K.3
-
36
-
-
79956326256
-
Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress
-
Zaugg K, Yao Y, Reilly PT, Kannan K, Kiarash R, Mason J et al. Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress. Genes Dev 2011; 25: 1041–1051.
-
(2011)
Genes Dev
, vol.25
, pp. 1041-1051
-
-
Zaugg, K.1
Yao, Y.2
Reilly, P.T.3
Kannan, K.4
Kiarash, R.5
Mason, J.6
-
37
-
-
84944197809
-
Targeting the leukemia cell metabolism by the CPT1a inhibition: Functional preclinical effects in leukemias
-
Ricciardi MR, Mirabilii S, Allegretti M, Licchetta R, Calarco A, Torrisi MR et al. Targeting the leukemia cell metabolism by the CPT1a inhibition: functional preclinical effects in leukemias. Blood 2015; 126: 1925–1929.
-
(2015)
Blood
, vol.126
, pp. 1925-1929
-
-
Ricciardi, M.R.1
Mirabilii, S.2
Allegretti, M.3
Licchetta, R.4
Calarco, A.5
Torrisi, M.R.6
-
38
-
-
84868573341
-
Molecular pathways: Tumor cells Co-opt the brain-specific metabolism gene CPT1C to promote survival
-
Reilly PT, Mak TW. Molecular pathways: tumor cells Co-opt the brain-specific metabolism gene CPT1C to promote survival. Clin Cancer Res 2012; 18: 5850–5855.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5850-5855
-
-
Reilly, P.T.1
Mak, T.W.2
-
39
-
-
84874947662
-
Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model
-
Sanchez-Macedo N, Feng J, Faubert B, Chang N, Elia A, Rushing EJ et al. Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model. Cell Death Differ 2013; 20: 659–668.
-
(2013)
Cell Death Differ
, vol.20
, pp. 659-668
-
-
Sanchez-Macedo, N.1
Feng, J.2
Faubert, B.3
Chang, N.4
Elia, A.5
Rushing, E.J.6
-
40
-
-
74949089659
-
Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction
-
Samudio I, Harmancey R, Fiegl M, Kantarjian H, Konopleva M, Korchin B et al. Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction. J Clin Invest 2010; 120: 142–156.
-
(2010)
J Clin Invest
, vol.120
, pp. 142-156
-
-
Samudio, I.1
Harmancey, R.2
Fiegl, M.3
Kantarjian, H.4
Konopleva, M.5
Korchin, B.6
-
41
-
-
44949149074
-
Potentiation of chemotherapeutic drugs by energy metabolism inhibitors 2-deoxyglucose and etomoxir
-
Hernlund E, Ihrlund LS, Khan O, Ates YO, Linder S, Panaretakis T et al. Potentiation of chemotherapeutic drugs by energy metabolism inhibitors 2-deoxyglucose and etomoxir. Int J Cancer 2008; 123: 476–483.
-
(2008)
Int J Cancer
, vol.123
, pp. 476-483
-
-
Hernlund, E.1
Ihrlund, L.S.2
Khan, O.3
Ates, Y.O.4
Linder, S.5
Panaretakis, T.6
-
42
-
-
84926618078
-
Lipid catabolism via CPT1 as a therapeutic target for prostate cancer
-
Schlaepfer IR, Rider L, Rodrigues LU, Gijon MA, Pac CT, Romero L et al. Lipid catabolism via CPT1 as a therapeutic target for prostate cancer. Mol Cancer Ther 2014; 13: 2361–2371.
-
(2014)
Mol Cancer Ther
, vol.13
, pp. 2361-2371
-
-
Schlaepfer, I.R.1
Rider, L.2
Rodrigues, L.U.3
Gijon, M.A.4
Pac, C.T.5
Romero, L.6
-
43
-
-
84927138932
-
ColoLipidGene: Signature of lipid metabolism-related genes to predict prognosis in stage-II colon cancer patients
-
Vargas T, Moreno-Rubio J, Herranz J, Cejas P, Molina S, Gonzalez-Vallinas M et al. ColoLipidGene: signature of lipid metabolism-related genes to predict prognosis in stage-II colon cancer patients. Oncotarget 2015; 6: 7348–7363.
-
(2015)
Oncotarget
, vol.6
, pp. 7348-7363
-
-
Vargas, T.1
Moreno-Rubio, J.2
Herranz, J.3
Cejas, P.4
Molina, S.5
Gonzalez-Vallinas, M.6
-
44
-
-
84878750384
-
On the future of mass-spectrometry-based lipidomics
-
Loizides-Mangold U. On the future of mass-spectrometry-based lipidomics. FEBS J 2013; 280: 2817–2829.
-
(2013)
FEBS J
, vol.280
, pp. 2817-2829
-
-
Loizides-Mangold, U.1
-
45
-
-
78149356322
-
Shedding new light on lipid biology with coherent anti-Stokes Raman scattering microscopy
-
Le TT, Yue S, Cheng JX. Shedding new light on lipid biology with coherent anti-Stokes Raman scattering microscopy. J Lipid Res 2010; 51: 3091–3102.
-
(2010)
J Lipid Res
, vol.51
, pp. 3091-3102
-
-
Le, T.T.1
Yue, S.2
Cheng, J.X.3
-
46
-
-
79955518028
-
Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression
-
Hilvo M, Denkert C, Lehtinen L, Muller B, Brockmoller S, Seppanen-Laakso T et al. Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression. Cancer Res 2011; 71: 3236–3245.
-
(2011)
Cancer Res
, vol.71
, pp. 3236-3245
-
-
Hilvo, M.1
Denkert, C.2
Lehtinen, L.3
Muller, B.4
Brockmoller, S.5
Seppanen-Laakso, T.6
-
47
-
-
84938623834
-
Spatially resolved metabolic phenotyping of breast cancer by desorption electrospray ionization mass spectrometry
-
Guenther S, Muirhead LJ, Speller AV, Golf O, Strittmatter N, Ramakrishnan R et al. Spatially resolved metabolic phenotyping of breast cancer by desorption electrospray ionization mass spectrometry. Cancer Res 2015; 75: 1828–1837.
-
(2015)
Cancer Res
, vol.75
, pp. 1828-1837
-
-
Guenther, S.1
Muirhead, L.J.2
Speller, A.V.3
Golf, O.4
Strittmatter, N.5
Ramakrishnan, R.6
-
48
-
-
34147092095
-
Polyunsaturation in lipid membranes: Dynamic properties and lateral pressure profiles
-
Ollila S, Hyvonen MT, Vattulainen I. Polyunsaturation in lipid membranes: dynamic properties and lateral pressure profiles. J Phys Chem B 2007; 111: 3139–3150.
-
(2007)
J Phys Chem B
, vol.111
, pp. 3139-3150
-
-
Ollila, S.1
Hyvonen, M.T.2
Vattulainen, I.3
-
49
-
-
84884987278
-
High-resolution imaging mass spectrometry reveals detailed spatial distribution of phosphatidylinositols in human breast cancer
-
Kawashima M, Iwamoto N, Kawaguchi-Sakita N, Sugimoto M, Ueno T, Mikami Y et al. High-resolution imaging mass spectrometry reveals detailed spatial distribution of phosphatidylinositols in human breast cancer. Cancer Sci 2013; 104: 1372–1379.
-
(2013)
Cancer Sci
, vol.104
, pp. 1372-1379
-
-
Kawashima, M.1
Iwamoto, N.2
Kawaguchi-Sakita, N.3
Sugimoto, M.4
Ueno, T.5
Mikami, Y.6
-
50
-
-
84904612313
-
Alteration of the lipid profile in lymphomas induced by MYC overexpression
-
Eberlin LS, Gabay M, Fan AC, Gouw AM, Tibshirani RJ, Felsher DW et al. Alteration of the lipid profile in lymphomas induced by MYC overexpression. Proc Natl Acad Sci USA 2014; 111: 10450–10455.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 10450-10455
-
-
Eberlin, L.S.1
Gabay, M.2
Fan, A.C.3
Gouw, A.M.4
Tibshirani, R.J.5
Felsher, D.W.6
-
51
-
-
84877342651
-
Characterization of MYC-induced tumorigenesis by in situ lipid profiling
-
Perry RH, Bellovin DI, Shroff EH, Ismail AI, Zabuawala T, Felsher DW et al. Characterization of MYC-induced tumorigenesis by in situ lipid profiling. Anal Chem 2013; 85: 4259–4262.
-
(2013)
Anal Chem
, vol.85
, pp. 4259-4262
-
-
Perry, R.H.1
Bellovin, D.I.2
Shroff, E.H.3
Ismail, A.I.4
Zabuawala, T.5
Felsher, D.W.6
-
52
-
-
84930216252
-
MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism
-
Shroff EH, Eberlin LS, Dang VM, Gouw AM, Gabay M, Adam SJ et al. MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism. Proc Natl Acad Sci USA 2015; 112: 6539–6544.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. 6539-6544
-
-
Shroff, E.H.1
Eberlin, L.S.2
Dang, V.M.3
Gouw, A.M.4
Gabay, M.5
Adam, S.J.6
-
53
-
-
55349102294
-
Cardiolipin and electron transport chain abnormalities in mouse brain tumor mitochondria: Lipidomic evidence supporting the Warburg theory of cancer
-
Kiebish MA, Han X, Cheng H, Chuang JH, Seyfried TN. Cardiolipin and electron transport chain abnormalities in mouse brain tumor mitochondria: lipidomic evidence supporting the Warburg theory of cancer. J Lipid Res 2008; 49: 2545–2556.
-
(2008)
J Lipid Res
, vol.49
, pp. 2545-2556
-
-
Kiebish, M.A.1
Han, X.2
Cheng, H.3
Chuang, J.H.4
Seyfried, T.N.5
-
54
-
-
74849118341
-
Lipid rafts as a membrane-organizing principle
-
Lingwood D, Simons K. Lipid rafts as a membrane-organizing principle. Science 2010; 327: 46–50.
-
(2010)
Science
, vol.327
, pp. 46-50
-
-
Lingwood, D.1
Simons, K.2
-
55
-
-
84920916855
-
Lipid rafts as major platforms for signaling regulation in cancer
-
Mollinedo F, Gajate C. Lipid rafts as major platforms for signaling regulation in cancer. Adv Biol Regul 2015; 57: 130–146.
-
(2015)
Adv Biol Regul
, vol.57
, pp. 130-146
-
-
Mollinedo, F.1
Gajate, C.2
-
56
-
-
39449130146
-
Bax activation and stressinduced apoptosis delayed by the accumulation of cholesterol in mitochondrial membranes
-
Lucken-Ardjomande S, Montessuit S, Martinou JC. Bax activation and stressinduced apoptosis delayed by the accumulation of cholesterol in mitochondrial membranes. Cell Death Differ 2008; 15: 484–493.
-
(2008)
Cell Death Differ
, vol.15
, pp. 484-493
-
-
Lucken-Ardjomande, S.1
Montessuit, S.2
Martinou, J.C.3
-
57
-
-
0028047154
-
Cholesterol content in tumor tissues is inversely associated with high-density lipoprotein cholesterol in serum in patients with gastrointestinal cancer
-
Dessi S, Batetta B, Pulisci D, Spano O, Anchisi C, Tessitore L et al. Cholesterol content in tumor tissues is inversely associated with high-density lipoprotein cholesterol in serum in patients with gastrointestinal cancer. Cancer 1994; 73: 253–258.
-
(1994)
Cancer
, vol.73
, pp. 253-258
-
-
Dessi, S.1
Batetta, B.2
Pulisci, D.3
Spano, O.4
Anchisi, C.5
Tessitore, L.6
-
59
-
-
48549093785
-
Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma
-
Montero J, Morales A, Llacuna L, Lluis JM, Terrones O, Basanez G et al. Mitochondrial cholesterol contributes to chemotherapy resistance in hepatocellular carcinoma. Cancer Res 2008; 68: 5246–5256.
-
(2008)
Cancer Res
, vol.68
, pp. 5246-5256
-
-
Montero, J.1
Morales, A.2
Llacuna, L.3
Lluis, J.M.4
Terrones, O.5
Basanez, G.6
-
60
-
-
33645457007
-
Elevated levels of cholesterol-rich lipid rafts in cancer cells are correlated with apoptosis sensitivity induced by cholesterol-depleting agents
-
quiz 1404-5
-
Li YC, Park MJ, Ye SK, Kim CW, Kim YN. Elevated levels of cholesterol-rich lipid rafts in cancer cells are correlated with apoptosis sensitivity induced by cholesterol-depleting agents. Am J Pathol 2006; 168: 1107–1118; quiz 1404-5.
-
(2006)
Am J Pathol
, vol.168
, pp. 1107-1118
-
-
Li, Y.C.1
Park, M.J.2
Ye, S.K.3
Kim, C.W.4
Kim, Y.N.5
-
61
-
-
84878125516
-
Molecular lipidomics of exosomes released by PC-3 prostate cancer cells
-
Llorente A, Skotland T, Sylvanne T, Kauhanen D, Rog T, Orlowski et al. Molecular lipidomics of exosomes released by PC-3 prostate cancer cells. Biochim Biophys Acta 2013; 1831: 1302–1309.
-
(2013)
Biochim Biophys Acta
, vol.1831
, pp. 1302-1309
-
-
Llorente, A.1
Skotland, T.2
Sylvanne, T.3
Kauhanen, D.4
Rogorlowski, T.5
-
62
-
-
0037162291
-
Identification of a plasma membrane Raftassociated PKB Ser473 kinase activity that is distinct from ILK and PDK1
-
Hill MM, Feng J, Hemmings BA. Identification of a plasma membrane Raftassociated PKB Ser473 kinase activity that is distinct from ILK and PDK1. Curr Biol 2002; 12: 1251–1255.
-
(2002)
Curr Biol
, vol.12
, pp. 1251-1255
-
-
Hill, M.M.1
Feng, J.2
Hemmings, B.A.3
-
63
-
-
34447134174
-
Cholesterol sensitivity of endogenous and myristoylated Akt
-
Adam RM, Mukhopadhyay NK, Kim J, Di Vizio D, Cinar B, Boucher K et al. Cholesterol sensitivity of endogenous and myristoylated Akt. Cancer Res 2007; 67: 6238–6246.
-
(2007)
Cancer Res
, vol.67
, pp. 6238-6246
-
-
Adam, R.M.1
Mukhopadhyay, N.K.2
Kim, J.3
Di Vizio, D.4
Cinar, B.5
Boucher, K.6
-
65
-
-
34548272131
-
Activation of PI3K-Akt signaling pathway promotes prostate cancer cell invasion
-
Shukla S, Maclennan GT, Hartman DJ, Fu P, Resnick MI, Gupta S. Activation of PI3K-Akt signaling pathway promotes prostate cancer cell invasion. Int J Cancer 2007; 121: 1424–1432.
-
(2007)
Int J Cancer
, vol.121
, pp. 1424-1432
-
-
Shukla, S.1
Maclennan, G.T.2
Hartman, D.J.3
Fu, P.4
Resnick, M.I.5
Gupta, S.6
-
66
-
-
33845575826
-
Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death
-
Borradaile NM, Han X, Harp JD, Gale SE, Ory DS, Schaffer JE. Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death. J Lipid Res 2006; 47: 2726–2737.
-
(2006)
J Lipid Res
, vol.47
, pp. 2726-2737
-
-
Borradaile, N.M.1
Han, X.2
Harp, J.D.3
Gale, S.E.4
Ory, D.S.5
Schaffer, J.E.6
-
67
-
-
16844372930
-
Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts
-
Zhuang L, Kim J, Adam RM, Solomon KR, Freeman MR. Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts. J Clin Invest 2005; 115: 959–968.
-
(2005)
J Clin Invest
, vol.115
, pp. 959-968
-
-
Zhuang, L.1
Kim, J.2
Adam, R.M.3
Solomon, K.R.4
Freeman, M.R.5
-
68
-
-
49649085353
-
Targeting lipid rafts inhibits protein kinase B by disrupting calcium homeostasis and attenuates malignant properties of melanoma cells
-
Fedida-Metula S, Elhyany S, Tsory S, Segal S, Hershfinkel M, Sekler I et al. Targeting lipid rafts inhibits protein kinase B by disrupting calcium homeostasis and attenuates malignant properties of melanoma cells. Carcinogenesis 2008; 29: 1546–1554.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1546-1554
-
-
Fedida-Metula, S.1
Elhyany, S.2
Tsory, S.3
Segal, S.4
Hershfinkel, M.5
Sekler, I.6
-
69
-
-
84884877185
-
Lipid raft regulates the initial spreading of melanoma A375 cells by modulating beta1 integrin clustering
-
Wang R, Bi J, Ampah KK, Zhang C, Li Z, Jiao Y et al. Lipid raft regulates the initial spreading of melanoma A375 cells by modulating beta1 integrin clustering. Int J Biochem Cell Biol 2013; 45: 1679–1689.
-
(2013)
Int J Biochem Cell Biol
, vol.45
, pp. 1679-1689
-
-
Wang, R.1
Bi, J.2
Ampah, K.K.3
Zhang, C.4
Li, Z.5
Jiao, Y.6
-
70
-
-
77954142537
-
Lipid raft modulation inhibits NSCLC cell migration through delocalization of the focal adhesion complex
-
Jeon JH, Kim SK, Kim HJ, Chang J, Ahn CM, Chang YS. Lipid raft modulation inhibits NSCLC cell migration through delocalization of the focal adhesion complex. Lung Cancer 2010; 69: 165–171.
-
(2010)
Lung Cancer
, vol.69
, pp. 165-171
-
-
Jeon, J.H.1
Kim, S.K.2
Kim, H.J.3
Chang, J.4
Ahn, C.M.5
Chang, Y.S.6
-
71
-
-
33750447940
-
Dimerization of CXCR4 in living malignant cells: Control of cell migration by a synthetic peptide that reduces homologous CXCR4 interactions
-
Wang J, He L, Combs CA, Roderiquez G, Norcross MA. Dimerization of CXCR4 in living malignant cells: control of cell migration by a synthetic peptide that reduces homologous CXCR4 interactions. Mol Cancer Ther 2006; 5: 2474–2483.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2474-2483
-
-
Wang, J.1
He, L.2
Combs, C.A.3
Roderiquez, G.4
Norcross, M.A.5
-
72
-
-
34547123570
-
Lipid rafts and nonrafts mediate tumor necrosis factor related apoptosis-inducing ligand induced apoptotic and nonapoptotic signals in non small cell lung carcinoma cells
-
Song JH, Tse MC, Bellail A, Phuphanich S, Khuri F, Kneteman NM et al. Lipid rafts and nonrafts mediate tumor necrosis factor related apoptosis-inducing ligand induced apoptotic and nonapoptotic signals in non small cell lung carcinoma cells. Cancer Res 2007; 67: 6946–6955.
-
(2007)
Cancer Res
, vol.67
, pp. 6946-6955
-
-
Song, J.H.1
Tse, M.C.2
Bellail, A.3
Phuphanich, S.4
Khuri, F.5
Kneteman, N.M.6
-
73
-
-
10644246821
-
Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells
-
Delmas D, Rebe C, Micheau O, Athias A, Gambert P, Grazide S et al. Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells. Oncogene 2004; 23: 8979–8986.
-
(2004)
Oncogene
, vol.23
, pp. 8979-8986
-
-
Delmas, D.1
Rebe, C.2
Micheau, O.3
Athias, A.4
Gambert, P.5
Grazide, S.6
-
74
-
-
84934755624
-
Stress responses from the endoplasmic reticulum in cancer
-
Kato H, Nishitoh H. Stress responses from the endoplasmic reticulum in cancer. Front Oncol 2015; 5: 93.
-
(2015)
Front Oncol
, vol.5
, pp. 93
-
-
Kato, H.1
Nishitoh, H.2
-
75
-
-
84869117975
-
Hypoxia causes triglyceride accumulation by HIF-1-mediated stimulation of lipin 1 expression
-
Mylonis I, Sembongi H, Befani C, Liakos P, Siniossoglou S, Simos G. Hypoxia causes triglyceride accumulation by HIF-1-mediated stimulation of lipin 1 expression. J Cell Sci 2012; 125: 3485–3493.
-
(2012)
J Cell Sci
, vol.125
, pp. 3485-3493
-
-
Mylonis, I.1
Sembongi, H.2
Befani, C.3
Liakos, P.4
Siniossoglou, S.5
Simos, G.6
-
76
-
-
84875242776
-
Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains
-
Volmer R, van der Ploeg K, Ron D. Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains. Proc Natl Acad Sci USA 2013; 110: 4628–4633.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 4628-4633
-
-
Volmer, R.1
van der Ploeg, K.2
Ron, D.3
-
77
-
-
84883163223
-
Membrane lipid saturation activates IRE1alpha without inducing clustering
-
Kitai Y, Ariyama H, Kono N, Oikawa D, Iwawaki T, Arai H. Membrane lipid saturation activates IRE1alpha without inducing clustering. Genes Cells 2013; 18: 798–809.
-
(2013)
Genes Cells
, vol.18
, pp. 798-809
-
-
Kitai, Y.1
Ariyama, H.2
Kono, N.3
Oikawa, D.4
Iwawaki, T.5
Arai, H.6
-
78
-
-
77954579285
-
Decrease in membrane phospholipid unsaturation induces unfolded protein response
-
Ariyama H, Kono N, Matsuda S, Inoue T, Arai H. Decrease in membrane phospholipid unsaturation induces unfolded protein response. J Biol Chem 2010; 285: 22027–22035.
-
(2010)
J Biol Chem
, vol.285
, pp. 22027-22035
-
-
Ariyama, H.1
Kono, N.2
Matsuda, S.3
Inoue, T.4
Arai, H.5
-
79
-
-
84877961669
-
Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth
-
Griffiths B, Lewis CA, Bensaad K, Ros S, Zhang Q, Ferber EC et al. Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth. Cancer Metab 2013; 1: 3.
-
(2013)
Cancer Metab
, vol.1
-
-
Griffiths, B.1
Lewis, C.A.2
Bensaad, K.3
Ros, S.4
Zhang, Q.5
Ferber, E.C.6
-
80
-
-
84877731629
-
An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity
-
Williams KJ, Argus JP, Zhu Y, Wilks MQ, Marbois BN, York AG et al. An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity. Cancer Res 2013; 73: 2850–2862.
-
(2013)
Cancer Res
, vol.73
, pp. 2850-2862
-
-
Williams, K.J.1
Argus, J.P.2
Zhu, Y.3
Wilks, M.Q.4
Marbois, B.N.5
York, A.G.6
-
81
-
-
84878515271
-
Alkylphospholipids deregulate cholesterol metabolism and induce cell-cycle arrest and autophagy in U-87 MG glioblastoma cells
-
Rios-Marco P, Martin-Fernandez M, Soria-Bretones I, Rios A, Carrasco MP, Marco C. Alkylphospholipids deregulate cholesterol metabolism and induce cell-cycle arrest and autophagy in U-87 MG glioblastoma cells. Biochim Biophys Acta 2013; 1831: 1322–1334.
-
(2013)
Biochim Biophys Acta
, vol.1831
, pp. 1322-1334
-
-
Rios-Marco, P.1
Martin-Fernandez, M.2
Soria-Bretones, I.3
Rios, A.4
Carrasco, M.P.5
Marco, C.6
-
82
-
-
84946191541
-
Cholesterol homeostasis and autophagic flux in perifosine-treated human hepatoblastoma HepG2 and glioblastoma U-87 MG cell lines
-
Rios-Marco P, Rios A, Jimenez-Lopez JM, Carrasco MP, Marco C. Cholesterol homeostasis and autophagic flux in perifosine-treated human hepatoblastoma HepG2 and glioblastoma U-87 MG cell lines. Biochem Pharmacol 2015; 96:10–19.
-
(2015)
Biochem Pharmacol
, vol.96
, pp. 10-19
-
-
Rios-Marco, P.1
Rios, A.2
Jimenez-Lopez, J.M.3
Carrasco, M.P.4
Marco, C.5
-
83
-
-
84946011735
-
Mitotane inhibits Sterol-O-Acyl Transferase 1 triggering lipid-mediated endoplasmic reticulum stress and apoptosis in adrenocortical carcinoma cells
-
Sbiera S, Leich E, Liebisch G, Sbiera I, Schirbel A, Wiemer L et al. Mitotane inhibits Sterol-O-Acyl Transferase 1 triggering lipid-mediated endoplasmic reticulum stress and apoptosis in adrenocortical carcinoma cells. Endocrinology 2015; 156: 3895–3908 en20151367.
-
(2015)
Endocrinology
, vol.156
, pp. 3895-3908
-
-
Sbiera, S.1
Leich, E.2
Liebisch, G.3
Sbiera, I.4
Schirbel, A.5
Wiemer, L.6
-
84
-
-
78149426794
-
Sphingolipids and cancer: Ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance
-
Ponnusamy S, Meyers-Needham M, Senkal CE, Saddoughi SA, Sentelle D, Selvam SP et al. Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance. Future Oncol 2010; 6: 1603–1624.
-
(2010)
Future Oncol
, vol.6
, pp. 1603-1624
-
-
Ponnusamy, S.1
Meyers-Needham, M.2
Senkal, C.E.3
Saddoughi, S.A.4
Sentelle, D.5
Selvam, S.P.6
-
85
-
-
84876074448
-
Targeting the ceramide system in cancer
-
Henry B, Moller C, Dimanche-Boitrel MT, Gulbins E, Becker KA. Targeting the ceramide system in cancer. Cancer Lett 2013; 332: 286–294.
-
(2013)
Cancer Lett
, vol.332
, pp. 286-294
-
-
Henry, B.1
Moller, C.2
Dimanche-Boitrel, M.T.3
Gulbins, E.4
Becker, K.A.5
-
86
-
-
33746138649
-
Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes
-
Carracedo A, Gironella M, Lorente M, Garcia S, Guzman M, Velasco G et al. Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes. Cancer Res 2006; 66: 6748–6755.
-
(2006)
Cancer Res
, vol.66
, pp. 6748-6755
-
-
Carracedo, A.1
Gironella, M.2
Lorente, M.3
Garcia, S.4
Guzman, M.5
Velasco, G.6
-
87
-
-
33645763253
-
The stressregulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells
-
Carracedo A, Lorente M, Egia A, Blazquez C, Garcia S, Giroux V et al. The stressregulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells. Cancer Cell 2006; 9: 301–312.
-
(2006)
Cancer Cell
, vol.9
, pp. 301-312
-
-
Carracedo, A.1
Lorente, M.2
Egia, A.3
Blazquez, C.4
Garcia, S.5
Giroux, V.6
-
88
-
-
66449115318
-
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
-
Salazar M, Carracedo A, Salanueva IJ, Hernandez-Tiedra S, Lorente M, Egia et al. Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J Clin Invest 2009; 119: 1359–1372.
-
(2009)
J Clin Invest
, vol.119
, pp. 1359-1372
-
-
Salazar, M.1
Carracedo, A.2
Salanueva, I.J.3
Hernandez-Tiedra, S.4
Lorenteegia, M.5
-
89
-
-
0033897314
-
Combined cytotoxic action of paclitaxel and ceramide against the human Tu138 head and neck squamous carcinoma cell line
-
Mehta S, Blackinton D, Omar I, Kouttab N, Myrick D, Klostergaard J et al. Combined cytotoxic action of paclitaxel and ceramide against the human Tu138 head and neck squamous carcinoma cell line. Cancer Chemother Pharmacol 2000; 46: 85–92.
-
(2000)
Cancer Chemother Pharmacol
, vol.46
, pp. 85-92
-
-
Mehta, S.1
Blackinton, D.2
Omar, I.3
Kouttab, N.4
Myrick, D.5
Klostergaard, J.6
-
90
-
-
33847376437
-
Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas
-
Senkal CE, Ponnusamy S, Rossi MJ, Bialewski J, Sinha D, Jiang JC et al. Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas. Mol Cancer Ther 2007; 6: 712–722.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 712-722
-
-
Senkal, C.E.1
Ponnusamy, S.2
Rossi, M.J.3
Bialewski, J.4
Sinha, D.5
Jiang, J.C.6
-
91
-
-
84928778302
-
Induction of ER stress-mediated apoptosis by ceramide via disruption of ER Ca(2+) homeostasis in human adenoid cystic carcinoma cells
-
Liu Z, Xia Y, Li B, Xu H, Wang C, Liu Y et al. Induction of ER stress-mediated apoptosis by ceramide via disruption of ER Ca(2+) homeostasis in human adenoid cystic carcinoma cells. Cell Biosci 2014; 4: 71.
-
(2014)
Cell Biosci
, vol.4
-
-
Liu, Z.1
Xia, Y.2
Li, B.3
Xu, H.4
Wang, C.5
Liu, Y.6
-
92
-
-
84858590826
-
Accessories to the crime: Functions of cells recruited to the tumor microenvironment
-
Hanahan D, Coussens LM. Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell 2012; 21: 309–322.
-
(2012)
Cancer Cell
, vol.21
, pp. 309-322
-
-
Hanahan, D.1
Coussens, L.M.2
-
93
-
-
81255157465
-
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
-
Nieman KM, Kenny HA, Penicka CV, Ladanyi A, Buell-Gutbrod R, Zillhardt MR et al. Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nat Med 2011; 17: 1498–1503.
-
(2011)
Nat Med
, vol.17
, pp. 1498-1503
-
-
Nieman, K.M.1
Kenny, H.A.2
Penicka, C.V.3
Ladanyi, A.4
Buell-Gutbrod, R.5
Zillhardt, M.R.6
-
94
-
-
34548178349
-
Direct evidence of lipid translocation between adipocytes and prostate cancer cells with imaging FTIR microspectroscopy
-
Gazi E, Gardner P, Lockyer NP, Hart CA, Brown MD, Clarke NW. Direct evidence of lipid translocation between adipocytes and prostate cancer cells with imaging FTIR microspectroscopy. J Lipid Res 2007; 48: 1846–1856.
-
(2007)
J Lipid Res
, vol.48
, pp. 1846-1856
-
-
Gazi, E.1
Gardner, P.2
Lockyer, N.P.3
Hart, C.A.4
Brown, M.D.5
Clarke, N.W.6
-
95
-
-
84937253537
-
The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1
-
Palm W, Park Y, Wright K, Pavlova NN, Tuveson DA, Thompson CB. The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1. Cell 2015; 162: 259–270.
-
(2015)
Cell
, vol.162
, pp. 259-270
-
-
Palm, W.1
Park, Y.2
Wright, K.3
Pavlova, N.N.4
Tuveson, D.A.5
Thompson, C.B.6
-
96
-
-
84878396462
-
Macropinocytosis of protein is an amino acid supply route in Rastransformed cells
-
Commisso C, Davidson SM, Soydaner-Azeloglu RG, Parker SJ, Kamphorst JJ, Hackett S et al. Macropinocytosis of protein is an amino acid supply route in Rastransformed cells. Nature 2013; 497: 633–637.
-
(2013)
Nature
, vol.497
, pp. 633-637
-
-
Commisso, C.1
Davidson, S.M.2
Soydaner-Azeloglu, R.G.3
Parker, S.J.4
Kamphorst, J.J.5
Hackett, S.6
-
97
-
-
84886738545
-
Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies
-
Record M, Carayon K, Poirot M, Silvente-Poirot S. Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies. Biochim Biophys Acta 2014; 1841: 108–120.
-
(2014)
Biochim Biophys Acta
, vol.1841
, pp. 108-120
-
-
Record, M.1
Carayon, K.2
Poirot, M.3
Silvente-Poirot, S.4
-
98
-
-
77956867597
-
Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins
-
Subra C, Grand D, Laulagnier K, Stella A, Lambeau G, Paillasse M et al. Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins. J Lipid Res 2010; 51: 2105–2120.
-
(2010)
J Lipid Res
, vol.51
, pp. 2105-2120
-
-
Subra, C.1
Grand, D.2
Laulagnier, K.3
Stella, A.4
Lambeau, G.5
Paillasse, M.6
-
99
-
-
84867673433
-
Exosomal lipids impact notch signaling and induce death of human pancreatic tumoral SOJ-6 cells
-
Beloribi S, Ristorcelli E, Breuzard G, Silvy F, Bertrand-Michel J, Beraud E et al. Exosomal lipids impact notch signaling and induce death of human pancreatic tumoral SOJ-6 cells. PLoS ONE 2012; 7: e47480.
-
(2012)
Plos ONE
, vol.7
-
-
Beloribi, S.1
Ristorcelli, E.2
Breuzard, G.3
Silvy, F.4
Bertrand-Michel, J.5
Beraud, E.6
-
100
-
-
64249115813
-
Induction of myeloidderived suppressor cells by tumor exosomes
-
Xiang X, Poliakov A, Liu C, Liu Y, Deng ZB, Wang J et al. Induction of myeloidderived suppressor cells by tumor exosomes. Int J Cancer 2009; 124: 2621–2633.
-
(2009)
Int J Cancer
, vol.124
, pp. 2621-2633
-
-
Xiang, X.1
Poliakov, A.2
Liu, C.3
Liu, Y.4
Deng, Z.B.5
Wang, J.6
-
101
-
-
34249300128
-
Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells
-
Sinha P, Clements VK, Fulton AM, Ostrand-Rosenberg S. Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells. Cancer Res 2007; 67: 4507–4513.
-
(2007)
Cancer Res
, vol.67
, pp. 4507-4513
-
-
Sinha, P.1
Clements, V.K.2
Fulton, A.M.3
Ostrand-Rosenberg, S.4
-
102
-
-
80051627660
-
M2 macrophages induced by prostaglandin E2 and IL-6 from cervical carcinoma are switched to activated M1 macrophages by CD4 + Th1 cells
-
Heusinkveld M, de Vos van Steenwijk PJ, Goedemans R, Ramwadhdoebe TH, Gorter A, Welters MJ et al. M2 macrophages induced by prostaglandin E2 and IL-6 from cervical carcinoma are switched to activated M1 macrophages by CD4 + Th1 cells. J Immunol 2011; 187: 1157–1165.
-
(2011)
J Immunol
, vol.187
, pp. 1157-1165
-
-
Heusinkveld, M.1
de Vos van Steenwijk, P.J.2
Goedemans, R.3
Ramwadhdoebe, T.H.4
Gorter, A.5
Welters, M.J.6
-
103
-
-
0347717578
-
Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression
-
Chang SH, Liu CH, Conway R, Han DK, Nithipatikom K, Trifan OC et al. Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression. Proc Natl Acad Sci USA 2004; 101: 591–596.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 591-596
-
-
Chang, S.H.1
Liu, C.H.2
Conway, R.3
Han, D.K.4
Nithipatikom, K.5
Trifan, O.C.6
-
104
-
-
0038489501
-
Potential involvement of the cyclooxygenase-2 pathway in the regulation of tumor-associated angiogenesis and growth in pancreatic cancer
-
Chu J, Lloyd FL, Trifan OC, Knapp B, Rizzo MT. Potential involvement of the cyclooxygenase-2 pathway in the regulation of tumor-associated angiogenesis and growth in pancreatic cancer. Mol Cancer Ther 2003; 2: 1–7.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 1-7
-
-
Chu, J.1
Lloyd, F.L.2
Trifan, O.C.3
Knapp, B.4
Rizzo, M.T.5
-
105
-
-
0003504049
-
Cyclooxygenase regulates angiogenesis induced by colon cancer cells
-
Tsujii M, Kawano S, Tsuji S, Sawaoka H, Hori M, DuBois RN. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 1998; 93: 705–716.
-
(1998)
Cell
, vol.93
, pp. 705-716
-
-
Tsujii, M.1
Kawano, S.2
Tsuji, S.3
Sawaoka, H.4
Hori, M.5
Dubois, R.N.6
-
106
-
-
84906834688
-
Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2,3-dioxygenase promotes breast cancer progression
-
Chen JY, Li CF, Kuo CC, Tsai KK, Hou MF, Hung WC. Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2,3-dioxygenase promotes breast cancer progression. Breast Cancer Res 2014; 16: 410.
-
(2014)
Breast Cancer Res
, vol.16
-
-
Chen, J.Y.1
Li, C.F.2
Kuo, C.C.3
Tsai, K.K.4
Hou, M.F.5
Hung, W.C.6
-
107
-
-
33644830810
-
Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages
-
Visentin B, Vekich JA, Sibbald BJ, Cavalli AL, Moreno KM, Matteo RG et al. Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages. Cancer Cell 2006; 9: 225–238.
-
(2006)
Cancer Cell
, vol.9
, pp. 225-238
-
-
Visentin, B.1
Vekich, J.A.2
Sibbald, B.J.3
Cavalli, A.L.4
Moreno, K.M.5
Matteo, R.G.6
-
108
-
-
31544447428
-
Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization
-
LaMontagne K, Littlewood-Evans A, Schnell C, O'Reilly T, Wyder L, Sanchez T et al. Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization. Cancer Res 2006; 66: 221–231.
-
(2006)
Cancer Res
, vol.66
, pp. 221-231
-
-
Lamontagne, K.1
Littlewood-Evans, A.2
Schnell, C.3
O'reilly, T.4
Wyder, L.5
Sanchez, T.6
-
109
-
-
77955801617
-
Role of sphingosine kinase-1 in paracrine/transcellular angiogenesis and lymphangiogenesis in vitro
-
Anelli V, Gault CR, Snider AJ, Obeid LM. Role of sphingosine kinase-1 in paracrine/transcellular angiogenesis and lymphangiogenesis in vitro. FASEB J 2010; 24: 2727–2738.
-
(2010)
FASEB J
, vol.24
, pp. 2727-2738
-
-
Anelli, V.1
Gault, C.R.2
Snider, A.J.3
Obeid, L.M.4
-
110
-
-
77950605484
-
Fatty acid synthase as a potential therapeutic target in cancer
-
Flavin R, Peluso S, Nguyen PL, Loda M. Fatty acid synthase as a potential therapeutic target in cancer. Future Oncol 2010; 6: 551–562.
-
(2010)
Future Oncol
, vol.6
, pp. 551-562
-
-
Flavin, R.1
Peluso, S.2
Nguyen, P.L.3
Loda, M.4
-
111
-
-
26644441651
-
ATP citrate lyase inhibition can suppress tumor cell growth
-
Hatzivassiliou G, Zhao F, Bauer DE, Andreadis C, Shaw AN, Dhanak D et al. ATP citrate lyase inhibition can suppress tumor cell growth. Cancer Cell 2005; 8: 311–321.
-
(2005)
Cancer Cell
, vol.8
, pp. 311-321
-
-
Hatzivassiliou, G.1
Zhao, F.2
Bauer, D.E.3
Andreadis, C.4
Shaw, A.N.5
Dhanak, D.6
-
112
-
-
84879904458
-
TOFA suppresses ovarian cancer cell growth in vitro and in vivo
-
Li S, Qiu L, Wu B, Shen H, Zhu J, Zhou L et al. TOFA suppresses ovarian cancer cell growth in vitro and in vivo. Mol Med Rep 2013; 8: 373–378.
-
(2013)
Mol Med Rep
, vol.8
, pp. 373-378
-
-
Li, S.1
Qiu, L.2
Wu, B.3
Shen, H.4
Zhu, J.5
Zhou, L.6
-
113
-
-
84928408498
-
Uncoupling nuclear receptor LXR and cholesterol metabolism in cancer
-
Bovenga F, Sabba C, Moschetta A. Uncoupling nuclear receptor LXR and cholesterol metabolism in cancer. Cell Metab 2015; 21: 517–526.
-
(2015)
Cell Metab
, vol.21
, pp. 517-526
-
-
Bovenga, F.1
Sabba, C.2
Moschetta, A.3
-
114
-
-
84937475615
-
Broad anti-tumor activity of a small molecule that selectively targets the Warburg effect and lipogenesis
-
Flaveny CA, Griffett K, El-Gendy Bel D, Kazantzis M, Sengupta M, Amelio AL et al. Broad anti-tumor activity of a small molecule that selectively targets the Warburg effect and lipogenesis. Cancer Cell 2015; 28: 42–56.
-
(2015)
Cancer Cell
, vol.28
, pp. 42-56
-
-
Flaveny, C.A.1
Griffett, K.2
El-Gendy Bel, D.3
Kazantzis, M.4
Sengupta, M.5
Amelio, A.L.6
-
115
-
-
84960802555
-
Recent progress in the discovery and development of stearoyl CoA desaturase inhibitors
-
e-pub ahead of print 3 September 2015
-
Uto Y. Recent progress in the discovery and development of stearoyl CoA desaturase inhibitors. Chem Phys Lipids (e-pub ahead of print 3 September 2015; doi: 10.1016/j.chemphyslip.2015.08.018).
-
Chem Phys Lipids
-
-
Uto, Y.1
-
116
-
-
65549125858
-
Antimetastatic effects of liposomal gemcitabine and empty liposomes in an orthotopic mouse model of pancreatic cancer
-
Graeser R, Bornmann C, Esser N, Ziroli V, Jantscheff P, Unger C et al. Antimetastatic effects of liposomal gemcitabine and empty liposomes in an orthotopic mouse model of pancreatic cancer. Pancreas 2009; 38: 330–337.
-
(2009)
Pancreas
, vol.38
, pp. 330-337
-
-
Graeser, R.1
Bornmann, C.2
Esser, N.3
Ziroli, V.4
Jantscheff, P.5
Unger, C.6
-
117
-
-
84924891316
-
The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination
-
Maione F, Oliaro-Bosso S, Meda C, Di Nicolantonio F, Bussolino F, Balliano G et al. The cholesterol biosynthesis enzyme oxidosqualene cyclase is a new target to impair tumour angiogenesis and metastasis dissemination. Sci Rep 2015; 5: 9054.
-
(2015)
Sci Rep
, vol.5
-
-
Maione, F.1
Oliaro-Bosso, S.2
Meda, C.3
Di Nicolantonio, F.4
Bussolino, F.5
Balliano, G.6
-
118
-
-
84870520448
-
Targeting tumor cell metabolism with statins
-
Clendening JW, Penn LZ. Targeting tumor cell metabolism with statins. Oncogene 2012; 31: 4967–4978.
-
(2012)
Oncogene
, vol.31
, pp. 4967-4978
-
-
Clendening, J.W.1
Penn, L.Z.2
-
119
-
-
84906791821
-
Novel prospects of statins as therapeutic agents in cancer
-
Pisanti S, Picardi P, Ciaglia E, D'Alessandro A, Bifulco M. Novel prospects of statins as therapeutic agents in cancer. Pharmacol Res 2014; 88: 84–98.
-
(2014)
Pharmacol Res
, vol.88
, pp. 84-98
-
-
Pisanti, S.1
Picardi, P.2
Ciaglia, E.3
D'alessandro, A.4
Bifulco, M.5
-
120
-
-
0031724078
-
Antiproliferative effect of methyl-betacyclodextrin in vitro and in human tumour xenografted athymic nude mice
-
Grosse PY, Bressolle F, Pinguet F. Antiproliferative effect of methyl-betacyclodextrin in vitro and in human tumour xenografted athymic nude mice. Br J Cancer 1998; 78: 1165–1169.
-
(1998)
Br J Cancer
, vol.78
, pp. 1165-1169
-
-
Grosse, P.Y.1
Bressolle, F.2
Pinguet, F.3
-
121
-
-
84908278358
-
Cholesterol depletion by methyl-beta-cyclodextrin augments tamoxifen induced cell death by enhancing its uptake in melanoma
-
Mohammad N, Malvi P, Meena AS, Singh SV, Chaube B, Vannuruswamy G et al. Cholesterol depletion by methyl-beta-cyclodextrin augments tamoxifen induced cell death by enhancing its uptake in melanoma. Mol Cancer 2014; 13: 204.
-
(2014)
Mol Cancer
, vol.13
-
-
Mohammad, N.1
Malvi, P.2
Meena, A.S.3
Singh, S.V.4
Chaube, B.5
Vannuruswamy, G.6
-
122
-
-
77952242043
-
Liver X Receptor activation downregulates AKT survival signaling in lipid rafts and induces apoptosis of prostate cancer cells
-
Pommier AJ, Alves G, Viennois E, Bernard S, Communal Y, Sion B et al. Liver X Receptor activation downregulates AKT survival signaling in lipid rafts and induces apoptosis of prostate cancer cells. Oncogene 2010; 29: 2712–2723.
-
(2010)
Oncogene
, vol.29
, pp. 2712-2723
-
-
Pommier, A.J.1
Alves, G.2
Viennois, E.3
Bernard, S.4
Communal, Y.5
Sion, B.6
-
123
-
-
84861101004
-
An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/ SREBP-1/LDLR-dependent pathway
-
Guo D, Reinitz F, Youssef M, Hong C, Nathanson D, Akhavan D et al. An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/ SREBP-1/LDLR-dependent pathway. Cancer Discov 2011; 1: 442–456.
-
(2011)
Cancer Discov
, vol.1
, pp. 442-456
-
-
Guo, D.1
Reinitz, F.2
Youssef, M.3
Hong, C.4
Nathanson, D.5
Akhavan, D.6
-
124
-
-
34547095531
-
Squalene synthase, a determinant of Raft-associated cholesterol and modulator of cancer cell proliferation
-
Brusselmans K, Timmermans L, Van de Sande T, Van Veldhoven PP, Guan G, Shechter I et al. Squalene synthase, a determinant of Raft-associated cholesterol and modulator of cancer cell proliferation. J Biol Chem 2007; 282: 18777–18785.
-
(2007)
J Biol Chem
, vol.282
, pp. 18777-18785
-
-
Brusselmans, K.1
Timmermans, L.2
van de Sande, T.3
van Veldhoven, P.P.4
Guan, G.5
Shechter, I.6
-
125
-
-
64549139703
-
Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells
-
Gajate C, Gonzalez-Camacho F, Mollinedo F. Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells. PLoS ONE 2009; 4: e5044.
-
(2009)
Plos ONE
, vol.4
-
-
Gajate, C.1
Gonzalez-Camacho, F.2
Mollinedo, F.3
-
126
-
-
33846243705
-
Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts
-
Gajate C, Mollinedo F. Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts. Blood 2007; 109: 711–719.
-
(2007)
Blood
, vol.109
, pp. 711-719
-
-
Gajate, C.1
Mollinedo, F.2
-
127
-
-
70349104624
-
Involvement of mitochondria and recruitment of Fas/CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions
-
Reis-Sobreiro M, Gajate C, Mollinedo F. Involvement of mitochondria and recruitment of Fas/CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions. Oncogene 2009; 28: 3221–3234.
-
(2009)
Oncogene
, vol.28
, pp. 3221-3234
-
-
Reis-Sobreiro, M.1
Gajate, C.2
Mollinedo, F.3
-
128
-
-
77949512481
-
Avicin D, a plant triterpenoid, induces cell apoptosis by recruitment of Fas and downstream signaling molecules into lipid rafts
-
Xu ZX, Ding T, Haridas V, Connolly F, Gutterman JU. Avicin D, a plant triterpenoid, induces cell apoptosis by recruitment of Fas and downstream signaling molecules into lipid rafts. PLoS ONE 2009; 4: e8532.
-
(2009)
Plos ONE
, vol.4
-
-
Xu, Z.X.1
Ding, T.2
Haridas, V.3
Connolly, F.4
Gutterman, J.U.5
-
129
-
-
79953303432
-
Nelfinavir induces liposarcoma apoptosis through inhibition of regulated intramembrane proteolysis of SREBP-1 and ATF6
-
Guan M, Fousek K, Jiang C, Guo S, Synold T, Xi B et al. Nelfinavir induces liposarcoma apoptosis through inhibition of regulated intramembrane proteolysis of SREBP-1 and ATF6. Clin Cancer Res 2011; 17: 1796–1806.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1796-1806
-
-
Guan, M.1
Fousek, K.2
Jiang, C.3
Guo, S.4
Synold, T.5
Xi, B.6
-
130
-
-
84928028956
-
Nelfinavir and nelfinavir analogs block site-2 protease cleavage to inhibit castration-resistant prostate cancer
-
Guan M, Su L, Yuan YC, Li H, Chow WA. Nelfinavir and nelfinavir analogs block site-2 protease cleavage to inhibit castration-resistant prostate cancer. Sci Rep 2015; 5: 9698.
-
(2015)
Sci Rep
, vol.5
, pp. 9698
-
-
Guan, M.1
Su, L.2
Yuan, Y.C.3
Li, H.4
Chow, W.A.5
-
131
-
-
84931281564
-
Nelfinavir and other protease inhibitors in cancer: Mechanisms involved in anticancer activity
-
Koltai T. Nelfinavir and other protease inhibitors in cancer: mechanisms involved in anticancer activity. F1000Res 2015; 4: 9.
-
(2015)
F1000res
, vol.4
, pp. 9
-
-
Koltai, T.1
-
132
-
-
33847034466
-
Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells
-
Little JL, Wheeler FB, Fels DR, Koumenis C, Kridel SJ. Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells. Cancer Res 2007; 67: 1262–1269.
-
(2007)
Cancer Res
, vol.67
, pp. 1262-1269
-
-
Little, J.L.1
Wheeler, F.B.2
Fels, D.R.3
Koumenis, C.4
Kridel, S.J.5
-
133
-
-
84877096404
-
Stearoyl-CoA desaturase 1 is a novel molecular therapeutic target for clear cell renal cell carcinoma
-
von Roemeling CA, Marlow LA, Wei JJ, Cooper SJ, Caulfield TR, Wu K et al. Stearoyl-CoA desaturase 1 is a novel molecular therapeutic target for clear cell renal cell carcinoma. Clin Cancer Res 2013; 19: 2368–2380.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 2368-2380
-
-
von Roemeling, C.A.1
Marlow, L.A.2
Wei, J.J.3
Cooper, S.J.4
Caulfield, T.R.5
Wu, K.6
-
134
-
-
33744539521
-
Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells
-
Obeng EA, Carlson LM, Gutman DM, Harrington WJ Jr., Lee KP, Boise LH. Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells. Blood 2006; 107: 4907–4916.
-
(2006)
Blood
, vol.107
, pp. 4907-4916
-
-
Obeng, E.A.1
Carlson, L.M.2
Gutman, D.M.3
Harrington, W.J.4
Lee, K.P.5
Boise, L.H.6
-
135
-
-
39049104489
-
Cannabinoids for cancer treatment: Progress and promise
-
Sarfaraz S, Adhami VM, Syed DN, Afaq F, Mukhtar H. Cannabinoids for cancer treatment: progress and promise. Cancer Res 2008; 68: 339–342.
-
(2008)
Cancer Res
, vol.68
, pp. 339-342
-
-
Sarfaraz, S.1
Adhami, V.M.2
Syed, D.N.3
Afaq, F.4
Mukhtar, H.5
-
136
-
-
78751527443
-
A combined preclinical therapy of cannabinoids and temozolomide against glioma
-
Torres S, Lorente M, Rodriguez-Fornes F, Hernandez-Tiedra S, Salazar M, Garcia Taboada E et al. A combined preclinical therapy of cannabinoids and temozolomide against glioma. Mol Cancer Ther 2011; 10: 90–103.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 90-103
-
-
Torres, S.1
Lorente, M.2
Rodriguez-Fornes, F.3
Hernandez-Tiedra, S.4
Salazar, M.5
Garcia Taboada, E.6
-
137
-
-
76849095665
-
The role of COX-2 in intestinal inflammation and colorectal cancer
-
Wang D, Dubois RN. The role of COX-2 in intestinal inflammation and colorectal cancer. Oncogene 2010; 29: 781–788.
-
(2010)
Oncogene
, vol.29
, pp. 781-788
-
-
Wang, D.1
Dubois, R.N.2
-
138
-
-
84903782541
-
COX-2 inhibition potentiates antiangiogenic cancer therapy and prevents metastasis in preclinical models
-
Xu L, Stevens J, Hilton MB, Seaman S, Conrads TP, Veenstra TD et al. COX-2 inhibition potentiates antiangiogenic cancer therapy and prevents metastasis in preclinical models. Sci Transl Med 2014; 6: 242ra84.
-
(2014)
Sci Transl Med
, vol.6
-
-
Xu, L.1
Stevens, J.2
Hilton, M.B.3
Seaman, S.4
Conrads, T.P.5
Veenstra, T.D.6
-
139
-
-
84922388823
-
Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance
-
Kurtova AV, Xiao J, Mo Q, Pazhanisamy S, Krasnow R, Lerner SP et al. Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance. Nature 2015; 517: 209–213.
-
(2015)
Nature
, vol.517
, pp. 209-213
-
-
Kurtova, A.V.1
Xiao, J.2
Mo, Q.3
Pazhanisamy, S.4
Krasnow, R.5
Lerner, S.P.6
-
140
-
-
84926518325
-
Aspirin and COX-2 inhibitor use in patients with stage III colon cancer
-
Ng K, Meyerhardt JA, Chan AT, Sato K, Chan JA, Niedzwiecki D et al. Aspirin and COX-2 inhibitor use in patients with stage III colon cancer. J Natl Cancer Inst 2015; 107: 345.
-
(2015)
J Natl Cancer Inst
, vol.107
, pp. 345
-
-
Ng, K.1
Meyerhardt, J.A.2
Chan, A.T.3
Sato, K.4
Chan, J.A.5
Niedzwiecki, D.6
-
141
-
-
84922880604
-
Combined treatment of breast cancer cell lines with vitamin D and COX-2 inhibitors
-
Thill M, Reichert K, Woeste A, Polack S, Fischer D, Hoellen F et al. Combined treatment of breast cancer cell lines with vitamin D and COX-2 inhibitors. Anticancer Res 2015; 35: 1189–1195.
-
(2015)
Anticancer Res
, vol.35
, pp. 1189-1195
-
-
Thill, M.1
Reichert, K.2
Woeste, A.3
Polack, S.4
Fischer, D.5
Hoellen, F.6
-
142
-
-
84909591975
-
Involvement of eicosanoids in the pathogenesis of pancreatic cancer: The roles of cyclooxygenase-2 and 5-lipoxygenase
-
Knab LM, Grippo PJ, Bentrem DJ. Involvement of eicosanoids in the pathogenesis of pancreatic cancer: the roles of cyclooxygenase-2 and 5-lipoxygenase. World J Gastroenterol 2014; 20: 10729–10739.
-
(2014)
World J Gastroenterol
, vol.20
, pp. 10729-10739
-
-
Knab, L.M.1
Grippo, P.J.2
Bentrem, D.J.3
-
143
-
-
84939884875
-
CG100649, a novel COX-2 inhibitor, inhibits colorectal adenoma and carcinoma growth in mouse models
-
Kim SH, Margalit O, Katoh H, Wang D, Wu H, Xia D et al. CG100649, a novel COX-2 inhibitor, inhibits colorectal adenoma and carcinoma growth in mouse models. Invest New Drugs 2014; 32: 1105–1112.
-
(2014)
Invest New Drugs
, vol.32
, pp. 1105-1112
-
-
Kim, S.H.1
Margalit, O.2
Katoh, H.3
Wang, D.4
Wu, H.5
Xia, D.6
-
144
-
-
84863057277
-
Sphingosine-1-phosphate produced by sphingosine kinase 1 promotes breast cancer progression by stimulating angiogenesis and lymphangiogenesis
-
Nagahashi M, Ramachandran S, Kim EY, Allegood JC, Rashid OM, Yamada et al. Sphingosine-1-phosphate produced by sphingosine kinase 1 promotes breast cancer progression by stimulating angiogenesis and lymphangiogenesis. Cancer Res 2012; 72: 726–735.
-
(2012)
Cancer Res
, vol.72
, pp. 726-735
-
-
Nagahashi, M.1
Ramachandran, S.2
Kim, E.Y.3
Allegood, J.C.4
Rashidyamada, O.M.5
-
145
-
-
84872406787
-
Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer
-
Liang J, Nagahashi M, Kim EY, Harikumar KB, Yamada A, Huang WC et al. Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer. Cancer Cell 2013; 23: 107–120.
-
(2013)
Cancer Cell
, vol.23
, pp. 107-120
-
-
Liang, J.1
Nagahashi, M.2
Kim, E.Y.3
Harikumar, K.B.4
Yamada, A.5
Huang, W.C.6
-
146
-
-
84927648765
-
Anti-S1P antibody as a novel therapeutic strategy for VEGFR TKI-resistant renal cancer
-
Zhang L, Wang X, Bullock AJ, Callea M, Shah H, Song J et al. Anti-S1P antibody as a novel therapeutic strategy for VEGFR TKI-resistant renal cancer. Clin Cancer Res 2015; 21: 1925–1934.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 1925-1934
-
-
Zhang, L.1
Wang, X.2
Bullock, A.J.3
Callea, M.4
Shah, H.5
Song, J.6
-
147
-
-
84891097577
-
Alkylphospholipids-a promising class of chemotherapeutic agents with a broad pharmacological spectrum
-
Pachioni Jde A, Magalhães JG, Lima EJ, Bueno Lde M, Barbosa JF, de Sá MM et al. Alkylphospholipids-a promising class of chemotherapeutic agents with a broad pharmacological spectrum. Pharm Pharm Sci 2013; 16: 742–759.
-
(2013)
Pharm Pharm Sci
, vol.16
, pp. 742-759
-
-
Pachioni Jde, A.1
Magalhães, J.G.2
Lima, E.J.3
Bueno Lde, M.4
Barbosa, J.F.5
de Sá, M.M.6
-
149
-
-
84886461893
-
Resveratrol and clinical trials: The crossroad from in vitro studies to human evidence
-
Tomé-Carneiro J, Larrosa M, González-Sarrías A, Tomás-Barberán FA, García-Conesa MT, Espín JC. Resveratrol and clinical trials: the crossroad from in vitro studies to human evidence. Curr Pharm Des 2013; 19: 6064–6093.
-
(2013)
Curr Pharm Des
, vol.19
, pp. 6064-6093
-
-
Tomé-Carneiro, J.1
Larrosa, M.2
González-Sarrías, A.3
Tomás-Barberán, F.A.4
García-Conesa, M.T.5
Espín, J.C.6
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