Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages

Cancer Cell

Volumn 9, Issue 3, 2006, Pages 225-238

  Visentin, Barbara ^a   Vekich, John A ^a   Sibbald, Bradley J ^a   Cavalli, Amy L ^b   Moreno, Kelli M ^b   Matteo, Rosalia G ^b   Garland, William A ^b   Lu, Yiling ^c   Yu, Shuangxing ^c   Hall, Hassan S ^c   Kundra, Vikas ^d   Mills, Gordon B ^c   Sabbadini, Roger A ^a,b  

^a SAN DIEGO STATE UNIVERSITY   (United States)

^b Lpath Inc ^*  (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CYTOKINE; MONOCLONAL ANTIBODY; PACLITAXEL; SPHINGOSINE 1 PHOSPHATE ANTIBODY; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER SURVIVAL; CARCINOGENESIS; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG INHIBITION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA; MURINAE;

EID: 33644830810     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2006.02.023     Document Type: Article

References (30)

1. M.L. Allende, and R.L. Proia Sphingosine-1-phosphate receptors and the development of the vascular system Biochim. Biophys. Acta 1582 2002 222 227
2. K.M. Argraves, B.A. Wilkerson, W.S. Argraves, P.A. Fleming, L.M. Obeid, and C.J. Drake Sphingosine-1-phosphate signaling promotes critical migratory events in vasculogenesis J. Biol. Chem. 279 2004 50580 50590
3. 2 G protein-coupled receptor. Requirement of inhibition of cellular RAC activity J. Biol. Chem. 278 2003 32841 32851
4. M. Beil, A. Micoulet, G. von Wichert, S. Paschke, P. Walther, M.B. Omary, P.P. Van Veldhoven, U. Gern, E. Wolff-Hieber, and J. Eggermann Sphingosylphosphorylcholine regulates keratin network architecture and visco-elastic properties of human cancer cells Nat. Cell Biol. 5 2003 803 811
5. M. Bektas, P.S. Jolly, C. Muller, J. Eberle, S. Spiegel, and C.C. Geilen Sphingosine kinase activity counteracts ceramide-mediated cell death in human melanoma cells: role of Bcl-2 expression Oncogene 24 2005 178 187
6. T. Clair, J. Aoki, E. Koh, R.W. Bandle, S.W. Nam, M.M. Ptaszynska, G.B. Mills, E. Schiffmann, L.A. Liotta, and M.L. Stracke Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate Cancer Res. 63 2003 5446 5453
7. N. Ferrara Vascular endothelial growth factor as a target for anticancer therapy Oncologist Suppl. 9 2004 2 10
8. K.J. French, R.S. Schrecengost, B.D. Lee, Y. Zhuang, S.N. Smith, J.L. Eberly, J.K. Yun, and C.D. Smith Discovery and evaluation of inhibitors of human sphingosine kinase Cancer Res. 63 2003 5962 5969
9. A. Gossmann, T.H. Helbich, S. Mesiano, D.M. Shames, M.F. Wendland, T.P. Roberts, N. Ferrara, R.B. Jaffe, and R.C. Brasch Magnetic resonance imaging in an experimental model of human ovarian cancer demonstrating altered microvascular permeability after inhibition of vascular endothelial growth factor Am. J. Obstet. Gynecol. 183 2000 956 963
10. V. Gouaze, M.E. Mirault, S. Carpentier, R. Salvayre, T. Levade, and N. Andrieu-Abadie Glutathione peroxidase-1 overexpression prevents ceramide production and partially inhibits apoptosis in doxorubicin-treated human breast carcinoma cells Mol. Pharmacol. 60 2001 488 496
11. 1 receptors in endothelial cells: implications for cross-talk between sphingolipid and growth factor receptors Proc. Natl. Acad. Sci. USA 100 2003 10664 10669
12. R. Ignoffo Overview of bevacizumab: a new cancer therapeutic strategy targeting vascular endothelial growth factor Am. J. Health Syst. Pharm. 61 2004 S21 S26
13. K.R. Johnson, K.Y. Johnson, H.G. Crellin, B. Ogretmen, A.M. Boylan, R.A. Harley, and L.M. Obeid Immunohistochemical distribution of sphingosine kinase 1 in normal and tumor lung tissue J. Histochem. Cytochem. 59 2005 1159 1166
14. R. Kolesnick, and Z. Fuks Radiation and ceramide-induced apoptosis Oncogene 22 2003 5897 5906
15. S.M. Kurinna, C.C. Tsao, A.F. Nica, T. Jiffar, and P.P. Ruvolo Ceramide promotes apoptosis in lung cancer-derived A549 cells by a mechanism involving c-Jun NH2-terminal kinase Cancer Res. 64 2004 7852 7856
16. Y.G. Kwon, J.K. Min, K.M. Kim, D.J. Lee, T.R. Billiar, and Y.M. Kim Sphingosine 1-phosphate protects human umbilical vein endothelial cells from serum-deprived apoptosis by nitric oxide production J. Biol. Chem. 276 2001 10627 10633
17. O.H. Lee, Y.M. Kim, Y.M. Lee, E.J. Moon, D.J. Lee, J.H. Kim, K.W. Kim, and Y.G. Kwon Sphingosine 1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical endothelial cells Biochem. Biophys. Res. Commun. 264 1999 743 750
18. T. Licht, L. Tsirulnikov, H. Reuveni, T. Yarnitzky, and S.A. Ben-Sasson Induction of pro-angiogenic signaling by a synthetic peptide derived from the second intracellular loop of S1P3 (EDG3) Blood 102 2003 2099 2107
19. M. Maceyka, S.G. Payne, S. Milstien, and S. Spiegel Sphingosine kinase, sphingosine-1-phosphate, and apoptosis Biochim. Biophys. Acta 1585 2002 193 201
20. B. Ogretmen, and Y.A. Hannun Biologically active sphingolipids in cancer pathogenesis and treatment Nat. Rev. Cancer 4 2004 604 616
21. J. Radeff-Huang, T.M. Seasholtz, R.G. Matteo, and J.H. Brown G protein mediated signaling pathways in lysophospholipid induced cell proliferation and survival J. Cell. Biochem. 92 2004 949 966
22. G.V. Richieri, A. Anel, and A.M. Kleinfeld Interactions of long-chain fatty acids and albumin: determination of free fatty acid levels using the fluorescent probe ADIFAB Biochemistry 32 1993 7574 7580
23. B.M. Schwartz, G. Hong, B.H. Morrison, W. Wu, L.M. Baudhuin, Y.J. Xiao, S.C. Mok, and Y. Xu Lysophospholipids increase interleukin-8 expression in ovarian cancer cells Gynecol. Oncol. 81 2001 291 300
24. S. Spiegel, and S. Milstien Sphingosine-1-phosphate: an enigmatic signalling lipid Nat. Rev. Mol. Cell Biol. 4 2003 397 407
25. C.A. Staton, S.M. Stribbling, S. Tazzyman, R. Hughes, N.J. Brown, and C.E. Lewis Current methods for assaying angiogenesis in vitro and in vivo Int. J. Exp. Pathol. 85 2004 233 248
26. Y. Takuwa Subtype-specific differential regulation of Rho family G proteins and cell migration by the Edg family sphingosine-1-phosphate receptors Biochim. Biophys. Acta 1582 2002 112 120
27. J.R. Van Brocklyn, C.A. Jackson, D.K. Pearl, M.S. Kotur, P.J. Snyder, and T.W. Prior Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme: roles of sphingosine kinase isoforms in growth of glioblastoma cell lines J. Neuropathol. Exp. Neurol. 64 2005 695 705
28. F. Wang, J.R. Van Brocklyn, J.P. Hobson, S. Movafagh, Z. Zukowska-Grojec, S. Milstien, and S. Spiegel Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis J. Biol. Chem. 274 1999 35343 35350
29. P. Xia, J.R. Gamble, L. Wang, S.M. Pitson, P.A. Moretti, B.W. Wattenberg, R.J. D'Andrea, and M.A. Vadas An oncogenic role of sphingosine kinase Curr. Biol. 10 2000 1527 1530
30. H. Yamaguchi, J. Kitayama, N. Takuwa, K. Arikawa, I. Inoki, K. Takehara, H. Nagawa, and Y. Takuwa Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and haematogenous metastasis of melanoma cells Biochem. J. 374 2003 715 722