Targeting lipid rafts inhibits protein kinase B by disrupting calcium homeostasis and attenuates malignant properties of melanoma cells

Carcinogenesis

Volumn 29, Issue 8, 2008, Pages 1546-1554

  Fedida Metula, Shlomit ^a   Elhyany, Shira ^a   Tsory, Sylvia ^a   Segal, Shraga ^a   Hershfinkel, Michal ^a   Sekler, Israel ^a   Fishman, Daniel ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALMODULIN INHIBITOR; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; METHYL BETA CYCLODEXTRIN; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CALCIUM HOMEOSTASIS; CALCIUM SIGNALING; CALCIUM TRANSPORT; CANCER INHIBITION; CARCINOGENESIS; CHELATION; CLONE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; HUMAN CELL; LIPID RAFT; MELANOMA; MELANOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION;

CALCIUM; CELL LINE, TUMOR; CELL SURVIVAL; FLOW CYTOMETRY; HOMEOSTASIS; HUMANS; MELANOMA; MEMBRANE MICRODOMAINS; MEMBRANE POTENTIALS; MICROSCOPY, CONFOCAL; MITOCHONDRIAL MEMBRANES; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 49649085353     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgn146     Document Type: Article

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