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Volumn 1831, Issue 8, 2013, Pages 1322-1334

Alkylphospholipids deregulate cholesterol metabolism and induce cell-cycle arrest and autophagy in U-87 MG glioblastoma cells

Author keywords

Alkylphospholipid; Autophagy; Cell cycle arrest; Cholesterol homeostasis; U 87 MG cell

Indexed keywords

3BETA (2 DIETHYLAMINOETHOXY)ANDROST 5 EN 17 ONE; ALKYLPHOSPHOLIPID DERIVATIVE; ANTINEOPLASTIC AGENT; CHOLESTEROL; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; EDELFOSINE; FILIPIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LACTATE DEHYDROGENASE; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MESSENGER RNA; PERIFOSINE; UNCLASSIFIED DRUG; VINBLASTINE; HMGCR PROTEIN, HUMAN; LAMP2 PROTEIN, HUMAN; LOW DENSITY LIPOPROTEIN RECEPTOR, HUMAN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN; PHOSPHOLIPID; TUMOR PROTEIN;

EID: 84878515271     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2013.05.004     Document Type: Article
Times cited : (18)

References (65)
  • 3
    • 77954401004 scopus 로고    scopus 로고
    • Acyl-coenzyme A: Cholesterol acyltransferase inhibitor Avasimibe affect survival and proliferation of glioma tumor cell lines
    • S. Bemlih, M.D. Poirier, A. Andaloussi, Acyl-coenzyme A: cholesterol acyltransferase inhibitor Avasimibe affect survival and proliferation of glioma tumor cell lines, Cancer Biol. Ther. 12 (2010) 1025-1032.
    • (2010) Cancer Biol. Ther. , vol.12 , pp. 1025-1032
    • Bemlih, S.1    Poirier, M.D.2    Andaloussi, A.3
  • 4
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • E.G. Bligh, W.J. Dyer, A rapid method of total lipid extraction and purification, Can. J. Biochem. Physiol. 37 (1959) 911-917.
    • (1959) Can. J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 5
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • M.M. Bradford, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem. 72 (1976) 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 7
    • 0034012322 scopus 로고    scopus 로고
    • Autophagic and apoptotic types of programmed cell death exhibit different fates of cytoskeletal filaments
    • W. Bursch, K. Hochegger, L. Torok, B. Marian, A. Ellinger, R.S. Hermann, Autophagic and apoptotic types of programmed cell death exhibit different fates of cytoskeletal filaments, J. Cell Sci. 113 (2000) 1189-1198. (Pubitemid 30229536)
    • (2000) Journal of Cell Science , vol.113 , Issue.7 , pp. 1189-1198
    • Bursch, W.1    Hochegger, K.2    Torok, L.3    Marian, B.4    Ellinger, A.5    Hermann, R.S.6
  • 8
    • 77951675862 scopus 로고    scopus 로고
    • Disruption of cellular cholesterol transport and homeostasis as a novel mechanism of action of membrane-targeted alkylphospholipid analogues
    • M.P. Carrasco, J.M. Jiménez-López, P. Ríos-Marco, J.L. Segovia, C. Marco, Disruption of cellular cholesterol transport and homeostasis as a novel mechanism of action of membrane-targeted alkylphospholipid analogues, Br. J. Pharmacol. 160 (2010) 355-366.
    • (2010) Br. J. Pharmacol. , vol.160 , pp. 355-366
    • Carrasco, M.P.1    Jiménez-López, J.M.2    Ríos-Marco, P.3    Segovia, J.L.4    Marco, C.5
  • 9
    • 79957485214 scopus 로고    scopus 로고
    • Perifosine selectively induces cell cycle block and modulates retinoblastoma and E2F1 protein levels in p53 mutated leukemic cell lines
    • C. Celeghini, R. Voltan, E. Rimondi, V. Gattei, G. Zauli, Perifosine selectively induces cell cycle block and modulates retinoblastoma and E2F1 protein levels in p53 mutated leukemic cell lines, Invest. New Drugs 29 (2011) 392-395.
    • (2011) Invest. New Drugs , vol.29 , pp. 392-395
    • Celeghini, C.1    Voltan, R.2    Rimondi, E.3    Gattei, V.4    Zauli, G.5
  • 10
    • 67349166918 scopus 로고    scopus 로고
    • Cholesterol synthesis inhibitor U18666A and the role of sterol metabolism and trafficking in numerous pathophysiological processes
    • J. Cenedella, Cholesterol synthesis inhibitor U18666A and the role of sterol metabolism and trafficking in numerous pathophysiological processes, Lipids 44 (2009) 477-487.
    • (2009) Lipids , vol.44 , pp. 477-487
    • Cenedella, J.1
  • 11
    • 0030943621 scopus 로고    scopus 로고
    • Acyl-coenzyme A:Cholesterol acyltransferase
    • T.Y. Chang, C.C. Chang, D. Cheng, Acyl-coenzyme A:cholesterol acyltransferase, Annu. Rev. Biochem. 66 (1997) 613-638.
    • (1997) Annu. Rev. Biochem. , vol.66 , pp. 613-638
    • Chang, T.Y.1    Chang, C.C.2    Cheng, D.3
  • 12
    • 33750318425 scopus 로고    scopus 로고
    • Mechanism of cholesterol transfer from the Niemann-Pick type C2 protein to model membranes supports a role in lysosomal cholesterol transport
    • DOI 10.1074/jbc.M602765200
    • S.R. Cheruku, Z. Xu, R. Dutia, P. Lobel, J. Storch, Mechanism of cholesterol transfer from the Niemann-Pick type C2 protein to model membranes supports a role in lysosomal cholesterol transport, J. Biol. Chem. 281 (2006) 31594-31604. (Pubitemid 46041425)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.42 , pp. 31594-31604
    • Cheruku, S.R.1    Xu, Z.2    Dutia, R.3    Lobel, P.4    Storch, J.5
  • 13
    • 84863954409 scopus 로고    scopus 로고
    • Regulation and function of autophagy during cell survival and cell death, Cold Spring Harb
    • (pii: a008813)
    • G. Das, B.V. Shravage, E.H. Baehrecke, Regulation and function of autophagy during cell survival and cell death, Cold Spring Harb. Perspect. Biol. 4 (2012), (pii: a008813).
    • (2012) Perspect. Biol. , vol.4
    • Das, G.1    Shravage, B.V.2    Baehrecke, E.H.3
  • 14
    • 3042563663 scopus 로고    scopus 로고
    • Human ATP-binding cassette transporter-2 (ABCA2) positively regulates low-density lipoprotein receptor expression and negatively regulates cholesterol esterification in Chinese hamster ovary cells
    • DOI 10.1016/j.bbalip.2004.04.009, PII S1388198104000678
    • W. Davis Jr., J.T. Boyd, K.E. Ile, K.D. Tew, Human ATP-binding cassette transporter-2 (ABCA2) positively regulates low-density lipoprotein receptor expression and negatively regulates cholesterol esterification in Chinese hamster ovary cells, Biochim. Biophys. Acta 1683 (2004) 89-100. (Pubitemid 38844663)
    • (2004) Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids , vol.1683 , Issue.1-3 , pp. 89-100
    • Davis Jr., W.1    Boyd, J.T.2    Ile, K.E.3    Tew, K.D.4
  • 15
    • 33747195058 scopus 로고    scopus 로고
    • Trends in brain cancer incidence and survival in the United States: Surveillance, Epidemiology, and End Results Program, 1973 to 2001
    • S. Deorah, C.F. Lynch, Z.A. Sibenaller, T.C. Ryken, Trends in brain cancer incidence and survival in the United States: surveillance, Epidemiology, and End Results Program, 1973 to 2001, Neurosurg. Focus. 20 (2006) E1.
    • (2006) Neurosurg. Focus. , vol.20
    • Deorah, S.1    Lynch, C.F.2    Sibenaller, Z.A.3    Ryken, T.C.4
  • 16
    • 0029808466 scopus 로고    scopus 로고
    • Cell cycle checkpoints: Preventing an identity crisis
    • DOI 10.1126/science.274.5293.1664
    • S.J. Elledge, Cell cycle checkpoints: preventing an identity crisis, Science 274 (1996) 1664-1672. (Pubitemid 26414889)
    • (1996) Science , vol.274 , Issue.5293 , pp. 1664-1672
    • Elledge, S.J.1
  • 17
    • 0031936591 scopus 로고    scopus 로고
    • Transport of cholesterol from the endoplasmic reticulum to the plasma membrane is constitutive in CaCo-2 cells and differs from the transport of plasma membrane cholesterol to the endoplasmic reticulum
    • F.J. Field, E. Born, S. Murthy, S.N. Mathur, Transport of cholesterol from the endoplasmic reticulum to the plasma membrane is constitutive in CaCo-2 cells and differs from the transport of plasma membrane cholesterol to the endoplasmic reticulum, J. Lipid Res. 39 (1998) 333-343. (Pubitemid 28100671)
    • (1998) Journal of Lipid Research , vol.39 , Issue.2 , pp. 333-343
    • Field, F.J.1    Born, E.2    Murthy, S.3    Mathur, S.N.4
  • 20
    • 69149089283 scopus 로고    scopus 로고
    • Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking
    • K.D. Harrison, R.Q. Miao, C. Fernandez-Hernándo, Y. Suárez, A. Dávalos, W.C. Sessa, Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking, Cell Metab. 10 (2009) 208-218.
    • (2009) Cell Metab. , vol.10 , pp. 208-218
    • Harrison, K.D.1    Miao, R.Q.2    Fernandez-Hernándo, C.3    Suárez, Y.4    Dávalos, A.5    Sessa, W.C.6
  • 21
    • 0035009282 scopus 로고    scopus 로고
    • Animal models of cell cycle dysregulation and the pathogenesis of gliomas
    • DOI 10.1023/A:1010609114564
    • E.C. Holland, Animal models of cell cycle dysregulation and the pathogenesis of gliomas, J. Neurooncol. 51 (2001) 265-276. (Pubitemid 32479299)
    • (2001) Journal of Neuro-Oncology , vol.51 , Issue.3 , pp. 265-276
    • Holland, E.C.1
  • 22
    • 38549141572 scopus 로고    scopus 로고
    • Cellular cholesterol trafficking and compartmentalization
    • DOI 10.1038/nrm2336, PII NRM2336
    • E. Ikonen, Cellular cholesterol trafficking and compartmentalization, Nat. Rev. Mol. Cell Biol. 9 (2008) 125-138. (Pubitemid 351158918)
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , Issue.2 , pp. 125-138
    • Ikonen, E.1
  • 23
    • 2442480496 scopus 로고    scopus 로고
    • Up-regulation of low-density lipoprotein receptor in human hepatocytes is induced by sequestration of free cholesterol in the endosomal/lysosomal compartment
    • DOI 10.1016/j.bcp.2004.03.006, PII S0006295204001820
    • M. Issandou, R. Guillard, A.B. Boullay, V. Linhart, E. Lopez-Perez, Up-regulation of low-density lipoprotein receptor in human hepatocytes is induced by sequestration of free cholesterol in the endosomal/lysosomal compartment, Biochem. Pharmacol. 67 (2004) 2281-2289. (Pubitemid 38639936)
    • (2004) Biochemical Pharmacology , vol.67 , Issue.12 , pp. 2281-2289
    • Issandou, M.1    Guillard, R.2    Boullay, A.-B.3    Linhart, V.4    Lopez-Perez, E.5
  • 25
    • 0034496406 scopus 로고    scopus 로고
    • Combination therapy of malignant glioma cells with 2-5A-antisense telomerase RNA and recombinant adenovirus p53
    • DOI 10.1038/sj.gt.3301327
    • T. Komata, Y. Kondo, S. Koga, S.C. Ko, L.W. Chung, S. Kondo, Combination therapy of malignant glioma cells with 2-5A-antisense telomerase RNA and recombinant adenovirus p53, Gene Ther. 7 (2000) 2071-2079. (Pubitemid 32118075)
    • (2000) Gene Therapy , vol.7 , Issue.24 , pp. 2071-2079
    • Komata, T.1    Kondo, Y.2    Koga, S.3    Ko, S.C.4    Chung, L.W.K.5    Kondo, S.6
  • 26
    • 0030977396 scopus 로고    scopus 로고
    • Quantitation of the pool of cholesterol associated with Acyl-CoA. Cholesterol acyltransferase in human fibroblasts
    • DOI 10.1074/jbc.272.20.13103
    • Y. Lange, T.L. Steck, Quantitation of the pool of cholesterol associated with acyl-CoA:cholesterol acyltransferase in human fibroblasts, J. Biol. Chem. 272 (1997) 13103-13108. (Pubitemid 27216733)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.20 , pp. 13103-13108
    • Lange, Y.1    Steck, T.L.2
  • 27
    • 0027972084 scopus 로고
    • Cholesterol homeostasis. Modulation by amphiphiles
    • Y. Lange, T.L. Steck, Cholesterol homeostasis. Modulation by amphiphiles, J. Biol. Chem. 269 (1994) 29371-29374. (Pubitemid 24365077)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.47 , pp. 29371-29374
    • Lange, Y.1    Steck, T.L.2
  • 28
    • 0032563304 scopus 로고    scopus 로고
    • Circulation of cholesterol between lysosomes and the plasma membrane
    • DOI 10.1074/jbc.273.30.18915
    • Y. Lange, J. Ye, T.L. Steck, Circulation of cholesterol between lysosomes and the plasma membrane, J. Biol. Chem. 273 (1998) 18915-18922. (Pubitemid 28366279)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.30 , pp. 18915-18922
    • Lange, Y.1    Ye, J.2    Steck, T.L.3
  • 29
    • 0027994354 scopus 로고
    • Cholesterol movement from plasma membrane to rough endoplasmic reticulum. Inhibition by progesterone
    • Y. Lange, Cholesterol movement from plasma membrane to rough endoplasmic reticulum. Inhibition by progesterone, J. Biol. Chem. 269 (1994) 3411-3414.
    • (1994) J. Biol. Chem. , vol.269 , pp. 3411-3414
    • Lange, Y.1
  • 31
    • 34147193472 scopus 로고    scopus 로고
    • Cell biology: Autophagy and cancer
    • DOI 10.1038/446745a, PII 446745A
    • B. Levine, Cell biology: autophagy and cancer, Nature 446 (2007) 745-747. (Pubitemid 46582063)
    • (2007) Nature , vol.446 , Issue.7137 , pp. 745-747
    • Levine, B.1
  • 32
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: Molecular mechanisms and biological functions of autophagy
    • DOI 10.1016/S1534-5807(04)00099-1, PII S1534580704000991
    • B. Levine, D.J. Klionsky, Development by self-digestion: molecular mechanisms and biological functions of autophagy, Dev. Cell 6 (2004) 463-477. (Pubitemid 38456176)
    • (2004) Developmental Cell , vol.6 , Issue.4 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 34
    • 4944230810 scopus 로고    scopus 로고
    • Intracellular trafficking of Niemann - Pick C proteins 1 and 2: Obligate components of subcellular lipid transport
    • DOI 10.1016/j.bbalip.2004.08.008, PII S1388198104001313
    • L. Liscum, S.L. Sturley, Intracellular trafficking of Niemann-Pick C proteins 1 and 2: obligate components of subcellular lipid transport, Biochim. Biophys. Acta 1685 (2004) 22-27. (Pubitemid 39328089)
    • (2004) Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids , vol.1685 , Issue.1-3 , pp. 22-27
    • Liscum, L.1    Sturley, S.L.2
  • 36
    • 60349120180 scopus 로고    scopus 로고
    • Hexadecylphosphocholine alters non vesicular cholesterol traffic from the plasma membrane to the endoplasmic reticulum and inhibits the synthesis of sphingomyelin in HepG2 cells
    • C. Marco, J.M. Jiménez-López, P. Ríos-Marco, J.L. Segovia, M.P. Carrasco, Hexadecylphosphocholine alters non vesicular cholesterol traffic from the plasma membrane to the endoplasmic reticulum and inhibits the synthesis of sphingomyelin in HepG2 cells, Int. J. Biochem. Cell Biol. 41 (2009) 1296-1303.
    • (2009) Int. J. Biochem. Cell Biol. , vol.41 , pp. 1296-1303
    • Marco, C.1    Jiménez-López, J.M.2    Ríos-Marco, P.3    Segovia, J.L.4    Carrasco, M.P.5
  • 37
    • 38849138585 scopus 로고    scopus 로고
    • Expression of two isozymes of acyl-coenzyme A: Cholesterol acyltransferase-1 and -2 in clear cell type renal cell carcinoma
    • DOI 10.1111/j.1442-2042.2007.01947.x
    • K. Matsumoto, Y. Fujiwara, R. Nagai, M. Yoshida, S. Ueda, Expression of two isozymes of acyl-coenzyme A: cholesterol acyltransferase-1 and -2 in clear cell type renal cell carcinoma, Int. J. Urol. 15 (2008) 166-170. (Pubitemid 351207308)
    • (2008) International Journal of Urology , vol.15 , Issue.2 , pp. 166-170
    • Matsumoto, K.1    Fujiwara, Y.2    Nagai, R.3    Yoshida, M.4    Ueda, S.5
  • 38
    • 28444479505 scopus 로고    scopus 로고
    • Role of cholesterol and lipid organization in disease
    • DOI 10.1038/nature04399
    • F.R. Maxfield, I. Tabas, Role of cholesterol and lipid organization in disease, Nature 438 (2005) 612-621. (Pubitemid 41740565)
    • (2005) Nature , vol.438 , Issue.7068 , pp. 612-621
    • Maxfield, F.R.1    Tabas, I.2
  • 39
    • 2342536384 scopus 로고    scopus 로고
    • Molecular regulation of SREBP function: The Insig-SCAP connection and isoform-specific modulation of lipid synthesis
    • DOI 10.1139/o03-090
    • R. McPherson, A. Gauthier, Molecular regulation of SREBP function: the Insig-SCAP connection and isoform-specific modulation of lipid synthesis, Biochem. Cell Biol. 82 (2004) 201-211. (Pubitemid 38580884)
    • (2004) Biochemistry and Cell Biology , vol.82 , Issue.1 , pp. 201-211
    • McPherson, R.1    Gauthier, A.2
  • 40
    • 81855211988 scopus 로고    scopus 로고
    • Early steps in steroidogenesis: Intracellular cholesterol trafficking
    • W.L. Miller, H.S. Bose, Early steps in steroidogenesis: intracellular cholesterol trafficking, J. Lipid Res. 52 (2011) 2111-2135.
    • (2011) J. Lipid Res. , vol.52 , pp. 2111-2135
    • Miller, W.L.1    Bose, H.S.2
  • 41
    • 0034947717 scopus 로고    scopus 로고
    • Golgi localization and phosphorylation of oxysterol binding protein in Niemann-Pick C and U18666A-treated cells
    • A. Mohammadi, R.J. Perry, M.K. Storey, H.W. Cook, D.M. Byers, N.D. Ridgway, Golgi localization and phosphorylation of oxysterol binding protein in Niemann-Pick C and U18666A-treated cells, J. Lipid Res. 42 (2001) 1062-1071. (Pubitemid 32645787)
    • (2001) Journal of Lipid Research , vol.42 , Issue.7 , pp. 1062-1071
    • Mohammadi, A.1    Perry, R.J.2    Storey, M.K.3    Cook, H.W.4    Byers, D.M.5    Ridgway, N.D.6
  • 45
    • 0030906263 scopus 로고    scopus 로고
    • Increased levels of cholesterol esters in glioma tissue and surrounding areas of human brain
    • DOI 10.1080/02688699746276
    • C. Nygren, H. von Holst, J.E. Mansson, P. Fredman, Increased levels of cholesterol esters in glioma tissue and surrounding areas of human brain, Br. J. Neurosurg. 11 (1997) 216-220. (Pubitemid 27254216)
    • (1997) British Journal of Neurosurgery , vol.11 , Issue.3 , pp. 216-220
    • Nygren, C.1    Von Holst, H.2    Mansson, J.-E.3    Fredman, P.4
  • 46
    • 0030612166 scopus 로고    scopus 로고
    • Mammalian G1 and G2 phase checkpoints
    • P.M. O'Connor, Mammalian G1 and G2 phase checkpoints, Cancer Surv. 29 (1997) 151-182.
    • (1997) Cancer Surv. , vol.29 , pp. 151-182
    • O'Connor, P.M.1
  • 47
    • 0034329025 scopus 로고    scopus 로고
    • Membrane traffic in sphingolipid storage diseases
    • R.E. Pagano, V. Puri, M. Dominguez, D.L. Marks, Membrane traffic in sphingolipid storage diseases, Traffic 11 (2000) 807-815.
    • (2000) Traffic , vol.11 , pp. 807-815
    • Pagano, R.E.1    Puri, V.2    Dominguez, M.3    Marks, D.L.4
  • 48
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PC
    • M.W. Pfaffl, A new mathematical model for relative quantification in real-time RT-PC, Nucleic Acids Res. 29 (2001) 2002-2007.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 2002-2007
    • Pfaffl, M.W.1
  • 49
    • 33244458202 scopus 로고    scopus 로고
    • Automated microscopy screening for compounds that partially revert cholesterol accumulation in Niemann-Pick C cells
    • DOI 10.1194/jlr.M500388-JLR200
    • N.H. Pipalia, A. Huang, H. Ralph, M. Rujoi, F.R. Maxfield, Automated microscopy screening for compounds that partially revert cholesterol accumulation in Niemann-Pick C cells, J. Lipid Res. 47 (2006) 284-301. (Pubitemid 43276914)
    • (2006) Journal of Lipid Research , vol.47 , Issue.2 , pp. 284-301
    • Pipalia, N.H.1    Huang, A.2    Ralph, H.3    Rujoi, M.4    Maxfield, F.R.5
  • 51
    • 84865635380 scopus 로고    scopus 로고
    • An antitubulin agent BCFMT inhibits proliferation of cancer cells and induces cell death by inhibiting microtubule dynamics
    • A. Rai, A. Surolia, D. Panda, An antitubulin agent BCFMT inhibits proliferation of cancer cells and induces cell death by inhibiting microtubule dynamics, PLoS One 7 (2012) e44311.
    • (2012) PLoS One , vol.7
    • Rai, A.1    Surolia, A.2    Panda, D.3
  • 52
    • 78651232046 scopus 로고    scopus 로고
    • Nonesterified cholesterol content of lysosomes modulates susceptibility to oxidant-induced permeabilization
    • J.J. Reiners Jr., M. Kleinman, D. Kessel, P.A. Mathieu, J.A. Caruso, Nonesterified cholesterol content of lysosomes modulates susceptibility to oxidant-induced permeabilization, Free Radic. Biol. Med. 15 (2011) 281-294.
    • (2011) Free Radic. Biol. Med. , vol.15 , pp. 281-294
    • Reiners Jr., J.J.1    Kleinman, M.2    Kessel, D.3    Mathieu, P.A.4    Caruso, J.A.5
  • 53
    • 52649114611 scopus 로고
    • The use of lead citrate at high pH as an electron-opaque stain in electron microscopy
    • E.S. Reynolds, The use of lead citrate at high pH as an electron-opaque stain in electron microscopy, J. Cell Biol. 17 (1963) 208-212.
    • (1963) J. Cell Biol. , vol.17 , pp. 208-212
    • Reynolds, E.S.1
  • 55
    • 17044414424 scopus 로고    scopus 로고
    • New insights into cyclins, CDKs, and cell cycle control
    • I. Sánchez, B.D. Dynlacht, New insights into cyclins, CDKs, and cell cycle control, Semin. Cell Dev. Biol. 16 (2005) 311-321.
    • (2005) Semin. Cell Dev. Biol. , vol.16 , pp. 311-321
    • Sánchez, I.1    Dynlacht, B.D.2
  • 56
    • 77956880594 scopus 로고    scopus 로고
    • A Dyn2-CIN85 complex mediates degradative traffic of the EGFR by regulation of late endosomal budding
    • B. Schroeder, S.G. Weller, J. Chen, D. Billadeau, M.A. McNiven, A Dyn2-CIN85 complex mediates degradative traffic of the EGFR by regulation of late endosomal budding, EMBO J. 29 (2010) 3039-3053.
    • (2010) EMBO J. , vol.29 , pp. 3039-3053
    • Schroeder, B.1    Weller, S.G.2    Chen, J.3    Billadeau, D.4    McNiven, M.A.5
  • 57
    • 0342316532 scopus 로고    scopus 로고
    • Oxysterols: Modulators of cholesterol metabolism and other processes
    • G.J. Schroepfer Jr., Oxysterols: modulators of cholesterol metabolism and other processes, Physiol. Rev. 80 (2000) 361-554. (Pubitemid 30060568)
    • (2000) Physiological Reviews , vol.80 , Issue.1 , pp. 361-554
    • Schroepfer Jr., G.J.1    Wilson, W.K.2
  • 58
    • 48849115866 scopus 로고    scopus 로고
    • Microtubule assembly dynamics: An attractive target for anticancer drugs
    • P. Singh, K. Rathinasamy, R. Mohan, D. Panda, Microtubule assembly dynamics: an attractive target for anticancer drugs, IUBMB Life 60 (2008) 368-375.
    • (2008) IUBMB Life , vol.60 , pp. 368-375
    • Singh, P.1    Rathinasamy, K.2    Mohan, R.3    Panda, D.4
  • 60
    • 34547123823 scopus 로고    scopus 로고
    • Oral miltefosine to treat leishmaniasis
    • J. Soto, P. Soto, Oral miltefosine to treat leishmaniasis, Biomedica 26 (2006) 207-217.
    • (2006) Biomedica , vol.26 , pp. 207-217
    • Soto, J.1    Soto, P.2
  • 61
    • 33747335165 scopus 로고    scopus 로고
    • Roles of endogenously synthesized sterols in the endocytic pathway
    • S. Sugii, S. Lin, N. Ohgami, M. Ohashi, C.C.Y. Chang, T. Chang, Roles of endogenously synthesized sterols in the endocytic pathway, J. Biol. Chem. 281 (2006) 23191-23206.
    • (2006) J. Biol. Chem. , vol.281 , pp. 23191-23206
    • Sugii, S.1    Lin, S.2    Ohgami, N.3    Ohashi, M.4    Chang, C.C.Y.5    Chang, T.6
  • 63
    • 23744440323 scopus 로고    scopus 로고
    • Cholesteryl esters in malignancy
    • DOI 10.1016/j.cccn.2005.04.003, PII S0009898105002421
    • M.R. Tosi, V. Tugnoli, Cholesteryl esters in malignancy, Clin. Chim. Acta 359 (2005) 27-45. (Pubitemid 41121953)
    • (2005) Clinica Chimica Acta , vol.359 , Issue.1-2 , pp. 27-45
    • Tosi, M.R.1    Tugnoli, V.2
  • 64
    • 52949108830 scopus 로고    scopus 로고
    • Anticancer alkylphospholipids: Mechanisms of action, cellular sensitivity and resistance, and clinical prospects
    • W.J. van Blitterswijk, M. Verheij, Anticancer alkylphospholipids: mechanisms of action, cellular sensitivity and resistance, and clinical prospects, Curr. Pharm. Des. 14 (2008) 2061-2074.
    • (2008) Curr. Pharm. Des. , vol.14 , pp. 2061-2074
    • Van Blitterswijk, W.J.1    Verheij, M.2
  • 65
    • 85027958500 scopus 로고    scopus 로고
    • Antidepressant drugs diversely affect autophagy pathways in astrocytes and neurons-dissociation from cholesterol homeostasis
    • J. Zschocke, N. Zimmermann, B. Berning, V. Ganal, F. Holsboer, T. Rein, Antidepressant drugs diversely affect autophagy pathways in astrocytes and neurons-dissociation from cholesterol homeostasis, Neuropsychopharmacology 36 (2011) 1754-1768.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 1754-1768
    • Zschocke, J.1    Zimmermann, N.2    Berning, B.3    Ganal, V.4    Holsboer, F.5    Rein, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.