-
1
-
-
13344285339
-
Identification and characterization of a new member of the TNF family that induces apoptosis
-
Wiley SR, Schooley K, Smolak PJ, et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 1991;3:673-82.
-
(1991)
Immunity
, vol.3
, pp. 673-682
-
-
Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
-
2
-
-
17544367410
-
Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
-
Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 1996;271:12687-90.
-
(1996)
J Biol Chem
, vol.271
, pp. 12687-12690
-
-
Pitti, R.M.1
Marsters, S.A.2
Ruppert, S.3
Donahue, C.J.4
Moore, A.5
Ashkenazi, A.6
-
3
-
-
0037240850
-
Nature's TRAIL - on a path to cancer immunotherapy
-
Smyth MJ, Takeda K, Hayakawa Y, Peschon JJ, van den Brink MR, Yagita H. Nature's TRAIL - on a path to cancer immunotherapy. Immunity 2003;18:1-6.
-
(2003)
Immunity
, vol.18
, pp. 1-6
-
-
Smyth, M.J.1
Takeda, K.2
Hayakawa, Y.3
Peschon, J.J.4
van den Brink, M.R.5
Yagita, H.6
-
4
-
-
17944376030
-
Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity
-
Ichikawa K, Liu W, Zhao L, et al. Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity. Nat Med 2001;7:954-60.
-
(2001)
Nat Med
, vol.7
, pp. 954-960
-
-
Ichikawa, K.1
Liu, W.2
Zhao, L.3
-
5
-
-
9244237679
-
TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice
-
Hao C, Song JH, Hsi B, et al. TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice. Cancer Res 2004;64:8502-6.
-
(2004)
Cancer Res
, vol.64
, pp. 8502-8506
-
-
Hao, C.1
Song, J.H.2
Hsi, B.3
-
6
-
-
34248190642
-
On the TRAIL toward death receptor-based cancer therapeutics
-
Gajewski TF. On the TRAIL toward death receptor-based cancer therapeutics. J Clin Oncol 2007;25:1305-7.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1305-1307
-
-
Gajewski, T.F.1
-
7
-
-
3142735020
-
Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand cooperates with chemotherapy to inhibit orthotopic lung tumor growth and improve survival
-
Jin H, Yang R, Fong S, et al. Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand cooperates with chemotherapy to inhibit orthotopic lung tumor growth and improve survival. Cancer Res 2004;64:4900-5.
-
(2004)
Cancer Res
, vol.64
, pp. 4900-4905
-
-
Jin, H.1
Yang, R.2
Fong, S.3
-
8
-
-
3042819210
-
Modulation of TRAIL signaling complex
-
Litwack G, editor, Academic Press Elsevier
-
Hao C, Song JH, Vilimanovich U, Kneteman N. M. Modulation of TRAIL signaling complex. In: Litwack G, editor. Vitamins and hormones. Academic Press (Elsevier); 2004. p. 81-99.
-
(2004)
Vitamins and hormones
, pp. 81-99
-
-
Hao, C.1
Song, J.H.2
Vilimanovich, U.3
Kneteman, N.M.4
-
9
-
-
0030925774
-
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
-
Medema JP, Scaffidi C, Kischkel FC, et al. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J 1997;16:2794-804.
-
(1997)
EMBO J
, vol.16
, pp. 2794-2804
-
-
Medema, J.P.1
Scaffidi, C.2
Kischkel, F.C.3
-
10
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
Li H, Zhu H, Xu CJ, Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998;94:491-501.
-
(1998)
Cell
, vol.94
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.J.3
Yuan, J.4
-
11
-
-
0032555716
-
-
Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998;94:481-90.
-
Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998;94:481-90.
-
-
-
-
12
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479-89.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
-
13
-
-
0034616945
-
-
Du C, Fang M, Li Y, Li L, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000;102:33-42.
-
Du C, Fang M, Li Y, Li L, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000;102:33-42.
-
-
-
-
14
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
Verhagen AM, Ekert PG, Pakusch M, et al. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 2000;102:43-53.
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
-
15
-
-
4444243683
-
A small molecule Smac mimic potentiates TRAIL- and TNFα-mediated cell death
-
Li L, Thomas RM, Suzuki H, De Brabander JK, Wang X, Harran PG. A small molecule Smac mimic potentiates TRAIL- and TNFα-mediated cell death. Science 2004;305:1471-4.
-
(2004)
Science
, vol.305
, pp. 1471-1474
-
-
Li, L.1
Thomas, R.M.2
Suzuki, H.3
De Brabander, J.K.4
Wang, X.5
Harran, P.G.6
-
16
-
-
0030916417
-
-
Liu X, Zou H, Slaughter C, Wang X. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 1997;89:175-84.
-
Liu X, Zou H, Slaughter C, Wang X. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 1997;89:175-84.
-
-
-
-
17
-
-
0029054725
-
-
Cell
-
Stanger BZ, Leder P, Lee TH, Kim E, Seed B. RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell 1995;81:513-23.
-
(1995)
RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death
, vol.81
, pp. 513-523
-
-
Stanger, B.Z.1
Leder, P.2
Lee, T.H.3
Kim, E.4
Seed, B.5
-
18
-
-
0031406386
-
Death receptor 5, a new member of the TNFR family,and DR4 induce FADD-dependent apoptosis and activate the NF-κB pathway
-
Chaudhary PM, Eby M, Jasmin A, Bookwalter A, Murray J, Hood L. Death receptor 5, a new member of the TNFR family,and DR4 induce FADD-dependent apoptosis and activate the NF-κB pathway. Immunity 1997;7:821-30.
-
(1997)
Immunity
, vol.7
, pp. 821-830
-
-
Chaudhary, P.M.1
Eby, M.2
Jasmin, A.3
Bookwalter, A.4
Murray, J.5
Hood, L.6
-
19
-
-
0037204948
-
TNF-R1 signaling: A beautiful pathway
-
Chen G, Goeddel DV. TNF-R1 signaling: a beautiful pathway. Science 2002;296:1634-5.
-
(2002)
Science
, vol.296
, pp. 1634-1635
-
-
Chen, G.1
Goeddel, D.V.2
-
20
-
-
0030800070
-
Inhibition of death receptor signals by cellular FLIP
-
Irmler M, Thome M, Hahne M, et al. Inhibition of death receptor signals by cellular FLIP. Nature 1997;388:190-5.
-
(1997)
Nature
, vol.388
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
-
21
-
-
0037067678
-
Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells
-
Xiao C, Yang BF, Asadi N, Beguinot F, Hao C. Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells. J Biol Chem 2002;277:25020-5.
-
(2002)
J Biol Chem
, vol.277
, pp. 25020-25025
-
-
Xiao, C.1
Yang, B.F.2
Asadi, N.3
Beguinot, F.4
Hao, C.5
-
22
-
-
1642386039
-
N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-κB signaling pathway
-
Kataoka T, Tschopp J. N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-κB signaling pathway. Mol Cell Biol 2004;24:2627-36.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 2627-2636
-
-
Kataoka, T.1
Tschopp, J.2
-
23
-
-
5644222552
-
Life and death decisions: Secondary complexes and lipid rafts in TNF receptor family signal transduction
-
Muppidi JR, Tschopp J, Siegel RM. Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction. Immunity 2004;21:461-5.
-
(2004)
Immunity
, vol.21
, pp. 461-465
-
-
Muppidi, J.R.1
Tschopp, J.2
Siegel, R.M.3
-
24
-
-
1142287412
-
Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death
-
Muppidi JR, Siegel RM. Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death. Nat Immunol 2004;5:182-9.
-
(2004)
Nat Immunol
, vol.5
, pp. 182-189
-
-
Muppidi, J.R.1
Siegel, R.M.2
-
25
-
-
0038742813
-
Recruitment of TNF receptor 1 to lipid rafts is essential for TNFα-mediated NF-κB activation
-
Legler DF, Micheau O, Doucey MA, Tschopp J, Bron C. Recruitment of TNF receptor 1 to lipid rafts is essential for TNFα-mediated NF-κB activation. Immunity 2003;18:655-64.
-
(2003)
Immunity
, vol.18
, pp. 655-664
-
-
Legler, D.F.1
Micheau, O.2
Doucey, M.A.3
Tschopp, J.4
Bron, C.5
-
26
-
-
2942614991
-
Differential regulation of TNF-R1 signaling: Lipid raft dependency of p42mapk/erk2 activation, but not NF-κB activation
-
Doan JE, Windmiller DA, Riches DW. Differential regulation of TNF-R1 signaling: lipid raft dependency of p42mapk/erk2 activation, but not NF-κB activation. J Immunol 2004;172:7654-60.
-
(2004)
J Immunol
, vol.172
, pp. 7654-7660
-
-
Doan, J.E.1
Windmiller, D.A.2
Riches, D.W.3
-
28
-
-
0037947828
-
Resistance of cell membranes to different detergents
-
Schuck S, Honsho M, Ekroos K, Shevchenko A, Simons K. Resistance of cell membranes to different detergents. Proc Natl Acad Sci U S A 2003;100:5795-800.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 5795-5800
-
-
Schuck, S.1
Honsho, M.2
Ekroos, K.3
Shevchenko, A.4
Simons, K.5
-
29
-
-
0026539931
-
The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product
-
Crews CM, Alessandrini A, Erikson RL. The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. Science 1992;258:478-80.
-
(1992)
Science
, vol.258
, pp. 478-480
-
-
Crews, C.M.1
Alessandrini, A.2
Erikson, R.L.3
-
30
-
-
33750586523
-
Constitutively activated nuclear factor-κB, but not induced NF-κB, leads to TRAIL resistance by upregulation of X-linked inhibitor of apoptosis protein in human cancer cells
-
Braeuer SJ, Buneker C, Mohr A, Zwacka RM. Constitutively activated nuclear factor-κB, but not induced NF-κB, leads to TRAIL resistance by upregulation of X-linked inhibitor of apoptosis protein in human cancer cells. Mol Cancer Res 2006;4:715-28.
-
(2006)
Mol Cancer Res
, vol.4
, pp. 715-728
-
-
Braeuer, S.J.1
Buneker, C.2
Mohr, A.3
Zwacka, R.M.4
-
31
-
-
34547109492
-
Human astrocytes are resistant to Fas ligand and tumor necrosis factor-related apoptosis-induced apoptosis
-
Song JH, Bellail A, Tse MCL, Yang VW, Hao C. Human astrocytes are resistant to Fas ligand and tumor necrosis factor-related apoptosis-induced apoptosis. J Neurosci 2006;26:1-10.
-
(2006)
J Neurosci
, vol.26
, pp. 1-10
-
-
Song, J.H.1
Bellail, A.2
Tse, M.C.L.3
Yang, V.W.4
Hao, C.5
-
32
-
-
0031253977
-
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
-
Wu GS, Burns TF, McDonald ER, et al. KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat Genet 1997;17:141-3.
-
(1997)
Nat Genet
, vol.17
, pp. 141-143
-
-
Wu, G.S.1
Burns, T.F.2
McDonald, E.R.3
-
33
-
-
0242667882
-
TRAIL triggers apoptosis in malignant glioma cells through extrinsic and intrinsic pathways
-
Song JH, Song DK, Pyrzynska B, Petruk KC, Van Meir EG, Hao C. TRAIL triggers apoptosis in malignant glioma cells through extrinsic and intrinsic pathways. Brain Pathol 2003;13:539-53.
-
(2003)
Brain Pathol
, vol.13
, pp. 539-553
-
-
Song, J.H.1
Song, D.K.2
Pyrzynska, B.3
Petruk, K.C.4
Van Meir, E.G.5
Hao, C.6
-
34
-
-
0042835740
-
Expression of TRAIL and TRAIL death receptors in stage III non-small cell lung cancer tumors
-
Spierings DC, de Vries EG, Timens W, Groen HJ, Boezen HM, de Jong S. Expression of TRAIL and TRAIL death receptors in stage III non-small cell lung cancer tumors. Clin Cancer Res 2003;9:3397-405.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3397-3405
-
-
Spierings, D.C.1
de Vries, E.G.2
Timens, W.3
Groen, H.J.4
Boezen, H.M.5
de Jong, S.6
-
35
-
-
0032713075
-
Safety and antitumor activity of recombinant soluble Apo2 ligand
-
Ashkenazi A, Pai RC, Fong S, et al. Safety and antitumor activity of recombinant soluble Apo2 ligand. J Clin Invest 1999;104:155-62.
-
(1999)
J Clin Invest
, vol.104
, pp. 155-162
-
-
Ashkenazi, A.1
Pai, R.C.2
Fong, S.3
-
36
-
-
0029949257
-
TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex
-
Hsu H, Huang J, Shu HB, Baichwal V, Goeddel DV. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 1996;4:387-96.
-
(1996)
Immunity
, vol.4
, pp. 387-396
-
-
Hsu, H.1
Huang, J.2
Shu, H.B.3
Baichwal, V.4
Goeddel, D.V.5
-
37
-
-
0033821215
-
The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IκB kinase and c-Jun N-terminal kinase
-
Lin Y, Devin A, Cook A, et al. The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IκB kinase and c-Jun N-terminal kinase. Mol Cell Biol 2000;20:6638-45.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6638-6645
-
-
Lin, Y.1
Devin, A.2
Cook, A.3
-
38
-
-
0033662433
-
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
-
Kischkel FC, Lawrence DA, Chuntharapai A, Schow P, Kim KJ, Ashkenazi A. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 2000;12:611-20.
-
(2000)
Immunity
, vol.12
, pp. 611-620
-
-
Kischkel, F.C.1
Lawrence, D.A.2
Chuntharapai, A.3
Schow, P.4
Kim, K.J.5
Ashkenazi, A.6
-
39
-
-
0035860696
-
Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-κB activation by inhibition of apical caspases
-
Harper N, Farrow SN, Kaptein A, Cohen GM, MacFarlane M. Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-κB activation by inhibition of apical caspases. J Biol Chem 2001;276:34743-52.
-
(2001)
J Biol Chem
, vol.276
, pp. 34743-34752
-
-
Harper, N.1
Farrow, S.N.2
Kaptein, A.3
Cohen, G.M.4
MacFarlane, M.5
-
41
-
-
0033662341
-
-
Yeh WC, Itie A, Elia AJ, et al. W. Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development. Immunity 2000;12:633-42.
-
Yeh WC, Itie A, Elia AJ, et al. W. Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development. Immunity 2000;12:633-42.
-
-
-
-
42
-
-
21444446872
-
Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis
-
Sharp DA, Lawrence DA, Ashkenazi A. Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis. J Biol Chem 2005;280:19401-9.
-
(2005)
J Biol Chem
, vol.280
, pp. 19401-19409
-
-
Sharp, D.A.1
Lawrence, D.A.2
Ashkenazi, A.3
-
43
-
-
18744425429
-
The caspase-8 inhibitor FLIP promotes activation of NF-κB and Erk signaling pathways
-
Kataoka T, Budd RC, Holler N, et al. The caspase-8 inhibitor FLIP promotes activation of NF-κB and Erk signaling pathways. Curr Biol 2000;10:640-8.
-
(2000)
Curr Biol
, vol.10
, pp. 640-648
-
-
Kataoka, T.1
Budd, R.C.2
Holler, N.3
-
44
-
-
0034743199
-
NF-κB signals induce the expression of c-FLIP
-
Micheau O, Lens S, Gaide O, Alevizopoulos K, Tschopp J. NF-κB signals induce the expression of c-FLIP. Mol Cell Biol 2001;21:5299-305.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5299-5305
-
-
Micheau, O.1
Lens, S.2
Gaide, O.3
Alevizopoulos, K.4
Tschopp, J.5
-
45
-
-
0033566163
-
The antiapoptotic decoy receptor TRID/TRAIL-R3 is a p53-regulated DNA damage-inducible gene that is overexpressed in primary tumors of the gastrointestinal tract
-
Sheikh MS, Huang Y, Fernandez-Salas EA, et al. The antiapoptotic decoy receptor TRID/TRAIL-R3 is a p53-regulated DNA damage-inducible gene that is overexpressed in primary tumors of the gastrointestinal tract. Oncogene 1999;18:4153-9.
-
(1999)
Oncogene
, vol.18
, pp. 4153-4159
-
-
Sheikh, M.S.1
Huang, Y.2
Fernandez-Salas, E.A.3
-
46
-
-
27144503348
-
Decoy receptor 2 (DcR2) is a p53 target gene and regulates chemosensitivity
-
Liu X, Yue P, Khuri FR, Sun SY. Decoy receptor 2 (DcR2) is a p53 target gene and regulates chemosensitivity. Cancer Res 2005;65:9169-75.
-
(2005)
Cancer Res
, vol.65
, pp. 9169-9175
-
-
Liu, X.1
Yue, P.2
Khuri, F.R.3
Sun, S.Y.4
-
47
-
-
0033989422
-
Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL
-
Gibson SB, Oyer R, Spalding AC, Anderson SM, Johnson GL. Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL. Mol Cell Biol 2000;20:205-12.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 205-212
-
-
Gibson, S.B.1
Oyer, R.2
Spalding, A.C.3
Anderson, S.M.4
Johnson, G.L.5
-
48
-
-
0032522463
-
p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor α
-
Sheikh MS, Burns TF, Huang Y, et al. p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor α. Cancer Res 1998;58:1593-8.
-
(1998)
Cancer Res
, vol.58
, pp. 1593-1598
-
-
Sheikh, M.S.1
Burns, T.F.2
Huang, Y.3
-
49
-
-
0141678063
-
Cisplatin down-regulation of cellular Fas-associated death domain-like interleukin-1h-converting enzyme-like inhibitory proteins to restore tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human melanoma cells
-
Song JH, Song DK, Herlyn M, Petruk KC, Hao C. Cisplatin down-regulation of cellular Fas-associated death domain-like interleukin-1h-converting enzyme-like inhibitory proteins to restore tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human melanoma cells. Clin Cancer Res 2003;9:4255-66.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4255-4266
-
-
Song, J.H.1
Song, D.K.2
Herlyn, M.3
Petruk, K.C.4
Hao, C.5
-
50
-
-
29244467982
-
Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae
-
Martin S, Phillips DC, Szekely-Szucs K, Elghazi L, Desmots F, Houghton JA. Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae. Cancer Res 2005;65:11447-58.
-
(2005)
Cancer Res
, vol.65
, pp. 11447-11458
-
-
Martin, S.1
Phillips, D.C.2
Szekely-Szucs, K.3
Elghazi, L.4
Desmots, F.5
Houghton, J.A.6
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