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Volumn 105, Issue 10, 2021, Pages 3883-3900

Synthesis and production of steviol glycosides: recent research trends and perspectives

Author keywords

Biotechnology; Diterpene glycoside; Secondary metabolism; Stevia

Indexed keywords

CULTIVATION; METABOLITES; PLANTS (BOTANY); SUGAR SUBSTITUTES; SUGARS;

EID: 85105534129     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-021-11306-x     Document Type: Review
Times cited : (44)

References (114)
  • 1
    • 85091199234 scopus 로고    scopus 로고
    • Effect of stevia aqueous extract on the antidiabetic activity of saxagliptin in diabetic rats
    • Abdel-Aal RA, Abdel-Rahman MS, Bayoumi SA, Ali LA (2021) Effect of stevia aqueous extract on the antidiabetic activity of saxagliptin in diabetic rats. J Ethnopharmacol 265:113188. 10.1016/j.jep.2020.113188 DOI: 10.1016/j.jep.2020.113188
    • (2021) J Ethnopharmacol , vol.265 , pp. 113188
    • Abdel-Aal, R.A.1    Abdel-Rahman, M.S.2    Bayoumi, S.A.3    Ali, L.A.4
  • 2
    • 85083051619 scopus 로고    scopus 로고
    • Effect of gibberellic acid on production of biomass, polyphenolics and steviol glycosides in adventitious root cultures of Stevia rebaudiana (Bert.)
    • COI: 1:CAS:528:DC%2BB3cXit1Crtb7O
    • Ahmad A, Ali H, Khan H, Begam A, Khan S, Ali SS, Ahmad N, Fazal H, Ali M, Hano C, Ahmad N, Abbasi BH (2020) Effect of gibberellic acid on production of biomass, polyphenolics and steviol glycosides in adventitious root cultures of Stevia rebaudiana (Bert.). Plants (Basel) 9:420
    • (2020) Plants (Basel) , vol.9 , pp. 420
    • Ahmad, A.1    Ali, H.2    Khan, H.3    Begam, A.4    Khan, S.5    Ali, S.S.6    Ahmad, N.7    Fazal, H.8    Ali, M.9    Hano, C.10    Ahmad, N.11    Abbasi, B.H.12
  • 4
    • 84888205489 scopus 로고    scopus 로고
    • Efficient regeneration for enhanced steviol glycosides production in Stevia rebaudiana (Bertoni)
    • COI: 1:CAS:528:DC%2BC3sXhslejt7bL
    • Aman N, Hadi F, Khalil SA, Zamir R, Ahmad N (2013) Efficient regeneration for enhanced steviol glycosides production in Stevia rebaudiana (Bertoni). C R Biol 36:486–492
    • (2013) C R Biol , vol.36 , pp. 486-492
    • Aman, N.1    Hadi, F.2    Khalil, S.A.3    Zamir, R.4    Ahmad, N.5
  • 6
    • 84982803608 scopus 로고    scopus 로고
    • Elicitor induced stevioside production, in vitro shoot growth, and biomass accumulation in micropropagated Stevia rebaudiana
    • COI: 1:CAS:528:DC%2BC28Xht1Okt77I
    • Bayraktar M, Naziri E, Akgun IH, Karabey F, Ilhan E, Akyol B, Bedir E, Gurel A (2016) Elicitor induced stevioside production, in vitro shoot growth, and biomass accumulation in micropropagated Stevia rebaudiana. Plant Cell Tissue Organ Cult 127:289–300
    • (2016) Plant Cell Tissue Organ Cult , vol.127 , pp. 289-300
    • Bayraktar, M.1    Naziri, E.2    Akgun, I.H.3    Karabey, F.4    Ilhan, E.5    Akyol, B.6    Bedir, E.7    Gurel, A.8
  • 7
    • 85089106571 scopus 로고    scopus 로고
    • Effect of NPK fertilization on the growth, yield, quality and mineral nutrition of new wweet plant in Morocco (Stevia rebaudiana Bertoni)
    • Benhmimou A, Ibriz M, Douaik A, Lage M, Al Faïz C, Si C, Zouahri A (2018) Effect of NPK fertilization on the growth, yield, quality and mineral nutrition of new wweet plant in Morocco (Stevia rebaudiana Bertoni). Am J Life Sci 6:36–43
    • (2018) Am J Life Sci , vol.6 , pp. 36-43
    • Benhmimou, A.1    Ibriz, M.2    Douaik, A.3    Lage, M.4    Al Faïz, C.5    Si, C.6    Zouahri, A.7
  • 8
    • 85095798593 scopus 로고    scopus 로고
    • Genotypic characterization and steviol glycoside quantification in a population of Stevia rebaudiana Bertoni from Paraguay
    • Bogado-Villalba L, Nakayama Nakashima H, Britos R, Masaru Iehisa JC, Flores Giubi MG (2020) Genotypic characterization and steviol glycoside quantification in a population of Stevia rebaudiana Bertoni from Paraguay. J Crop Sci Biotechnol 24:145–152. 10.1007/s12892-020-00066-1 DOI: 10.1007/s12892-020-00066-1
    • (2020) J Crop Sci Biotechnol , vol.24 , pp. 145-152
    • Bogado-Villalba, L.1    Nakayama Nakashima, H.2    Britos, R.3    Masaru Iehisa, J.C.4    Flores Giubi, M.G.5
  • 9
    • 0032334681 scopus 로고    scopus 로고
    • Effects of exogenous growth regulators on callusogenesis and growth of cultured cells of Stevia rebaudiana Bertoni
    • COI: 1:CAS:528:DyaK1cXntlSmt7o%3D
    • Bondarev NI, Nosov AM, Kornienko AV (1998) Effects of exogenous growth regulators on callusogenesis and growth of cultured cells of Stevia rebaudiana Bertoni. Russ J Plant Physiol 45:770–777
    • (1998) Russ J Plant Physiol , vol.45 , pp. 770-777
    • Bondarev, N.I.1    Nosov, A.M.2    Kornienko, A.V.3
  • 10
    • 0034978929 scopus 로고    scopus 로고
    • Peculiarities of diterpenoid steviol glycoside production in in vitro cultures of Stevia rebaudiana Bertoni
    • COI: 1:CAS:528:DC%2BD3MXjvV2rtr8%3D
    • Bondarev N, Reshetnyak O, Nosov A (2001) Peculiarities of diterpenoid steviol glycoside production in in vitro cultures of Stevia rebaudiana Bertoni. Plant Sci 161:155–163
    • (2001) Plant Sci , vol.161 , pp. 155-163
    • Bondarev, N.1    Reshetnyak, O.2    Nosov, A.3
  • 11
    • 0842323805 scopus 로고    scopus 로고
    • Steviol glycoside content in different organs of Stevia rebaudiana and its dynamics during ontogeny
    • COI: 1:CAS:528:DC%2BD2cXkslelsg%3D%3D
    • Bondarev N, Sukhanova MA, Reshetnyak OV, Nosov AM (2003) Steviol glycoside content in different organs of Stevia rebaudiana and its dynamics during ontogeny. Biol Plant 47:261–264
    • (2003) Biol Plant , vol.47 , pp. 261-264
    • Bondarev, N.1    Sukhanova, M.A.2    Reshetnyak, O.V.3    Nosov, A.M.4
  • 12
    • 85068160014 scopus 로고    scopus 로고
    • Impact of cultivation factors in vitro on the growth and the biosynthesis of steviol glycosides in Stevia rebaudiana cell cultures
    • COI: 1:CAS:528:DC%2BC1MXht1WmtbbL, PID: 31402827
    • Bondarev N, Reshetnyak O, Bondareva T, Il’in M, Nosov A (2019) Impact of cultivation factors in vitro on the growth and the biosynthesis of steviol glycosides in Stevia rebaudiana cell cultures. Physiol Mol Biol Plants 25:1091–1096
    • (2019) Physiol Mol Biol Plants , vol.25 , pp. 1091-1096
    • Bondarev, N.1    Reshetnyak, O.2    Bondareva, T.3    Il’in, M.4    Nosov, A.5
  • 13
    • 0000018712 scopus 로고
    • Heritability for yield, leaf: stem ratio and stevioside content estimated from a landrace cultivar of Stevia rebaudiana
    • COI: 1:CAS:528:DyaK3sXhvVOqt78%3D
    • Brandle JE, Rosa N (1992) Heritability for yield, leaf: stem ratio and stevioside content estimated from a landrace cultivar of Stevia rebaudiana. Can J Plant Sci 72:1263–1266
    • (1992) Can J Plant Sci , vol.72 , pp. 1263-1266
    • Brandle, J.E.1    Rosa, N.2
  • 14
    • 34447101720 scopus 로고    scopus 로고
    • Steviol glycoside biosynthesis
    • Brandle JE, Telmer PG (2007) Steviol glycoside biosynthesis. Phytochemistry 68:1855–1863
    • (2007) Phytochemistry , vol.68 , pp. 1855-1863
    • Brandle, J.E.1    Telmer, P.G.2
  • 15
    • 0032441205 scopus 로고    scopus 로고
    • Stevia rebaudiana: its agricultural, biological, and chemical properties
    • COI: 1:CAS:528:DyaK1MXks1amtg%3D%3D
    • Brandle JE, Starratt AN, Gijzen M (1998) Stevia rebaudiana: its agricultural, biological, and chemical properties. Can J Plant Sci 78:527–536
    • (1998) Can J Plant Sci , vol.78 , pp. 527-536
    • Brandle, J.E.1    Starratt, A.N.2    Gijzen, M.3
  • 16
    • 0036836919 scopus 로고    scopus 로고
    • Leaf ESTs from Stevia rebaudiana: a resource for gene discovery in diterpene synthesis
    • COI: 1:CAS:528:DC%2BD38Xms1ektr0%3D, PID: 12374295
    • Brandle J, Richman A, Swanson AK, Chapman BP (2002) Leaf ESTs from Stevia rebaudiana: a resource for gene discovery in diterpene synthesis. Plant Mol Biol 50:613–622
    • (2002) Plant Mol Biol , vol.50 , pp. 613-622
    • Brandle, J.1    Richman, A.2    Swanson, A.K.3    Chapman, B.P.4
  • 19
    • 85019082218 scopus 로고    scopus 로고
    • Salt-tolerance mechanisms induced in Stevia rebaudiana Bertoni: effects on mineral nutrition, antioxidative metabolism and steviol glycoside content
    • COI: 1:CAS:528:DC%2BC2sXns1ars7k%3D, PID: 28500994
    • Cantabella D, Piqueras A, Acosta-Motos JR, Bernal-Vicente A, Hernández JA, Díaz-Vivancos P (2017) Salt-tolerance mechanisms induced in Stevia rebaudiana Bertoni: effects on mineral nutrition, antioxidative metabolism and steviol glycoside content. Plant Physiol Biochem 115:484–496
    • (2017) Plant Physiol Biochem , vol.115 , pp. 484-496
    • Cantabella, D.1    Piqueras, A.2    Acosta-Motos, J.R.3    Bernal-Vicente, A.4    Hernández, J.A.5    Díaz-Vivancos, P.6
  • 20
    • 85109059478 scopus 로고    scopus 로고
    • Membrane separation processes for the extraction and purification of steviol glycosides: an overview
    • Castro-Muñoz R, Díaz-Montes E, Cassano A, Gontarek E (2020) Membrane separation processes for the extraction and purification of steviol glycosides: an overview. Crit Rev Food Sci Nutr 4:1–23
    • (2020) Crit Rev Food Sci Nutr , vol.4 , pp. 1-23
    • Castro-Muñoz, R.1    Díaz-Montes, E.2    Cassano, A.3    Gontarek, E.4
  • 21
    • 84879634195 scopus 로고    scopus 로고
    • Steviol glycosides: chemical diversity, metabolism, and function
    • COI: 1:CAS:528:DC%2BC3sXosVeit74%3D, PID: 23713723
    • Ceunen S, Geuns JMC (2013a) Steviol glycosides: chemical diversity, metabolism, and function. J Nat Prod 76:1201–1228
    • (2013) J Nat Prod , vol.76 , pp. 1201-1228
    • Ceunen, S.1    Geuns, J.M.C.2
  • 22
    • 84868557387 scopus 로고    scopus 로고
    • Influence of photoperiodism on the spatio-temporal accumulation of steviol glycosides in Stevia rebaudiana (Bertoni)
    • (, b
    • Ceunen S, Geuns JMC (2013b) Influence of photoperiodism on the spatio-temporal accumulation of steviol glycosides in Stevia rebaudiana (Bertoni). Plant Sci 198:72–82
    • (2013) Plant Sci , vol.198 , pp. 72-82
    • Ceunen, S.1    Geuns, J.M.C.2
  • 23
    • 84858863828 scopus 로고    scopus 로고
    • Stimulation of steviol glycoside accumulation in Stevia rebaudiana by red LED light
    • Ceunen S, Werbrouck S, Geuns JMC (2012) Stimulation of steviol glycoside accumulation in Stevia rebaudiana by red LED light. J Plant Physiol 169:749–752
    • (2012) J Plant Physiol , vol.169 , pp. 749-752
    • Ceunen, S.1    Werbrouck, S.2    Geuns, J.M.C.3
  • 24
    • 79955680679 scopus 로고    scopus 로고
    • Structures of the novel diterpene glycosides from Stevia rebaudiana
    • COI: 1:CAS:528:DC%2BC3MXlvVait7k%3D, PID: 21489412
    • Chaturvedula VS, Prakash I (2011a) Structures of the novel diterpene glycosides from Stevia rebaudiana. Carbohydr Res 346:1057–1060
    • (2011) Carbohydr Res , vol.346 , pp. 1057-1060
    • Chaturvedula, V.S.1    Prakash, I.2
  • 25
    • 80054789750 scopus 로고    scopus 로고
    • Additional minor diterpene glycosides from Stevia rebaudiana
    • COI: 1:CAS:528:DC%2BC3MXhtVKqtLfO, PID: 21922898
    • Chaturvedula VS, Prakash I (2011b) Additional minor diterpene glycosides from Stevia rebaudiana. Nat Prod Commun 6:1059–1062
    • (2011) Nat Prod Commun , vol.6 , pp. 1059-1062
    • Chaturvedula, V.S.1    Prakash, I.2
  • 26
    • 79954469829 scopus 로고    scopus 로고
    • Two minor diterpene glycosides from the leaves of Stevia rebaudiana
    • COI: 1:CAS:528:DC%2BC3MXisFKrtL0%3D, PID: 21425668
    • Chaturvedula VS, Rhea J, Milanowski D, Mocek U, Prakash I (2011) Two minor diterpene glycosides from the leaves of Stevia rebaudiana. Nat Prod Commun 6:175–178
    • (2011) Nat Prod Commun , vol.6 , pp. 175-178
    • Chaturvedula, V.S.1    Rhea, J.2    Milanowski, D.3    Mocek, U.4    Prakash, I.5
  • 27
    • 84903664613 scopus 로고    scopus 로고
    • RNA-Seq for gene identification and transcript profiling of three S. rebaudiana genotypes [J]
    • PID: 25001368
    • Chen J, Hou K, Qin P, Liu H, Yi B, Yang W, Wu W (2014) RNA-Seq for gene identification and transcript profiling of three S. rebaudiana genotypes [J]. BMC Genomics 15:571
    • (2014) BMC Genomics , vol.15 , pp. 571
    • Chen, J.1    Hou, K.2    Qin, P.3    Liu, H.4    Yi, B.5    Yang, W.6    Wu, W.7
  • 28
    • 85044757730 scopus 로고    scopus 로고
    • Synthesis of rebaudioside D, using glycosyltransferase UGTSL2 and in situ UDP-glucose regeneration
    • Chen L, Sun P, Zhou F, Li Y, Chen K, Jia H, Yan M, Gong D, Ouyang P (2018) Synthesis of rebaudioside D, using glycosyltransferase UGTSL2 and in situ UDP-glucose regeneration. Food Chem 259:286–291
    • (2018) Food Chem , vol.259 , pp. 286-291
    • Chen, L.1    Sun, P.2    Zhou, F.3    Li, Y.4    Chen, K.5    Jia, H.6    Yan, M.7    Gong, D.8    Ouyang, P.9
  • 30
    • 79958756782 scopus 로고    scopus 로고
    • An economic analysis of Stevia (Stevia rebaudiana Bert.) cultivation through stem cutting and tissue culture propagule in India
    • Das A, Biswas M, Mandal N (2010) An economic analysis of Stevia (Stevia rebaudiana Bert.) cultivation through stem cutting and tissue culture propagule in India. Trends Agric Econ 3:216–222
    • (2010) Trends Agric Econ , vol.3 , pp. 216-222
    • Das, A.1    Biswas, M.2    Mandal, N.3
  • 31
    • 85030563859 scopus 로고    scopus 로고
    • Effect of salinity on gene expression, morphological and biochemical characteristics of Stevia rebaudiana Bertoni under in vitro conditions
    • COI: 1:STN:280:DC%2BC1cbhtlynsQ%3D%3D, PID: 28838348
    • Fallah F, Nokhasi F, Ghaheri M, Kahrizi D, Beheshti AAA, Ghorbani T, Kazemi E, Ansarypou Z (2017) Effect of salinity on gene expression, morphological and biochemical characteristics of Stevia rebaudiana Bertoni under in vitro conditions. Cell Mol Biol 63:102–103
    • (2017) Cell Mol Biol , vol.63 , pp. 102-103
    • Fallah, F.1    Nokhasi, F.2    Ghaheri, M.3    Kahrizi, D.4    Beheshti, A.A.A.5    Ghorbani, T.6    Kazemi, E.7    Ansarypou, Z.8
  • 32
    • 84921053927 scopus 로고    scopus 로고
    • Production of chlorogenic acid and its derivatives in hairy root cultures of Stevia rebaudiana
    • COI: 1:CAS:528:DC%2BC2cXitFCrs7vE, PID: 25548875
    • Fu X, Yin ZP, Chen JG, Shangguan XC, Wang X, Zhang QF, Peng DY (2015) Production of chlorogenic acid and its derivatives in hairy root cultures of Stevia rebaudiana. J Agric Food Chem 63:262–268
    • (2015) J Agric Food Chem , vol.63 , pp. 262-268
    • Fu, X.1    Yin, Z.P.2    Chen, J.G.3    Shangguan, X.C.4    Wang, X.5    Zhang, Q.F.6    Peng, D.Y.7
  • 33
    • 85099001800 scopus 로고    scopus 로고
    • Induced autopolyploidy—a promising approach for enhanced biosynthesis of plant secondary metabolites: an insight
    • PID: 33417015
    • Gantait S, Mukherjee E (2021) Induced autopolyploidy—a promising approach for enhanced biosynthesis of plant secondary metabolites: an insight. J Genet Eng Biotechnol 19:4
    • (2021) J Genet Eng Biotechnol , vol.19 , pp. 4
    • Gantait, S.1    Mukherjee, E.2
  • 34
    • 84938545183 scopus 로고    scopus 로고
    • Stevia: a comprehensive review on ethnopharmacological properties and in vitro regeneration
    • Gantait S, Das A, Mandal N (2015) Stevia: a comprehensive review on ethnopharmacological properties and in vitro regeneration. Sugar Tech 17:95–106
    • (2015) Sugar Tech , vol.17 , pp. 95-106
    • Gantait, S.1    Das, A.2    Mandal, N.3
  • 35
    • 85031999731 scopus 로고    scopus 로고
    • Geographical distribution, botanical description and self-incompatibility mechanism of genus Stevia
    • Gantait S, Das A, Banerjee J (2018) Geographical distribution, botanical description and self-incompatibility mechanism of genus Stevia. Sugar Tech 20:1–10. 10.1007/s12355-017-0563-1 DOI: 10.1007/s12355-017-0563-1
    • (2018) Sugar Tech , vol.20 , pp. 1-10
    • Gantait, S.1    Das, A.2    Banerjee, J.3
  • 36
    • 85083072166 scopus 로고    scopus 로고
    • Biotechnological interventions for ginsenosides production
    • Gantait S, Mitra M, Chen JT (2020) Biotechnological interventions for ginsenosides production. Biomolecules 10:538. 10.3390/biom10040538 DOI: 10.3390/biom10040538
    • (2020) Biomolecules , vol.10 , pp. 538
    • Gantait, S.1    Mitra, M.2    Chen, J.T.3
  • 37
    • 85099222496 scopus 로고    scopus 로고
    • Advances in biotechnology of Emblica officinalis Gaertn. syn. Phyllanthus emblica L.: a nutraceuticals-rich fruit tree with multifaceted ethnomedicinal uses
    • (,),.,:,., https://doi.org/10.1007/s13205-020-02615-5
    • Gantait S, Mahanta M, Bera S, Verma SK (2021) Advances in biotechnology of Emblica officinalis Gaertn. syn. Phyllanthus emblica L.: a nutraceuticals-rich fruit tree with multifaceted ethnomedicinal uses. 3 Biotech 11:62. 10.1007/s13205-020-02615-5
    • (2021) 3 Biotech , vol.11
    • Gantait, S.1    Mahanta, M.2    Bera, S.3    Verma, S.K.4
  • 38
    • 84997107870 scopus 로고    scopus 로고
    • Stevia glycosides: chemical and enzymatic modifications of their carbohydrate moieties to improve the sweet-tasting quality
    • PID: 27816105
    • Gerwig GJ, Te Poele EM, Dijkhuizen L, Kamerling JP (2016) Stevia glycosides: chemical and enzymatic modifications of their carbohydrate moieties to improve the sweet-tasting quality. Adv Carbohydr Chem Biochem 73:1–72
    • (2016) Adv Carbohydr Chem Biochem , vol.73 , pp. 1-72
    • Gerwig, G.J.1    Te Poele, E.M.2    Dijkhuizen, L.3    Kamerling, J.P.4
  • 39
    • 85058527372 scopus 로고    scopus 로고
    • A Combinatorial approach to study cytochrome P450 enzymes for de novo production of steviol glucosides in baker's yeast
    • COI: 1:CAS:528:DC%2BC1cXit1ynsbnN, PID: 30474973
    • Gold ND, Fossati E, Hansen CC, DiFalco M, Douchin V, Martin VJJ (2018) A Combinatorial approach to study cytochrome P450 enzymes for de novo production of steviol glucosides in baker's yeast. ACS Synth Biol 7:2918–2929
    • (2018) ACS Synth Biol , vol.7 , pp. 2918-2929
    • Gold, N.D.1    Fossati, E.2    Hansen, C.C.3    DiFalco, M.4    Douchin, V.5    Martin, V.J.J.6
  • 40
    • 84883311835 scopus 로고    scopus 로고
    • Agrobacterium mediated transient gene silencing (AMTS) in Stevia rebaudiana: insights into steviol glycoside biosynthesis pathway
    • COI: 1:CAS:528:DC%2BC3sXhsVGitb3J, PID: 24023961
    • Guleria P, Yadav SK (2013a) Agrobacterium mediated transient gene silencing (AMTS) in Stevia rebaudiana: insights into steviol glycoside biosynthesis pathway. PLoS ONE 8:e74731
    • (2013) PLoS ONE , vol.8
    • Guleria, P.1    Yadav, S.K.2
  • 41
    • 84867240294 scopus 로고    scopus 로고
    • Insights into steviol glycoside biosynthesis pathway enzymes through structural homology modeling
    • COI: 1:CAS:528:DC%2BC3sXptVWmu7Y%3D
    • Guleria P, Yadav SK (2013b) Insights into steviol glycoside biosynthesis pathway enzymes through structural homology modeling. Am J Biochem Mol Biol 3:1–19
    • (2013) Am J Biochem Mol Biol , vol.3 , pp. 1-19
    • Guleria, P.1    Yadav, S.K.2
  • 42
  • 43
    • 84899491955 scopus 로고    scopus 로고
    • Effect of salts (NaCl and Na 2 CO 3) on callus and suspension culture of Stevia rebaudiana for steviol glycoside production
    • 3) on callus and suspension culture of Stevia rebaudiana for steviol glycoside production. Appl Biochem Biotechnol 172:2894–2906
    • (2014) Appl Biochem Biotechnol , vol.172 , pp. 2894-2906
    • Gupta, P.1    Sharma, S.2    Saxena, S.3
  • 44
    • 84937815038 scopus 로고    scopus 로고
    • Biomass yield and steviol glycoside production in callus and suspension culture of Stevia rebaudiana treated with proline and polyethylene glycol
    • COI: 1:CAS:528:DC%2BC2MXotVSrsbY%3D, PID: 25940589
    • Gupta P, Sharma S, Saxena S (2015) Biomass yield and steviol glycoside production in callus and suspension culture of Stevia rebaudiana treated with proline and polyethylene glycol. Appl Biochem Biotechnol 176:863–874
    • (2015) Appl Biochem Biotechnol , vol.176 , pp. 863-874
    • Gupta, P.1    Sharma, S.2    Saxena, S.3
  • 45
    • 84964336818 scopus 로고    scopus 로고
    • Effect of abiotic stress on growth parameters and steviol glycoside content in Stevia rebaudiana (Bertoni) raised in vitro
    • Gupta P, Sharma S, Saxena S (2016) Effect of abiotic stress on growth parameters and steviol glycoside content in Stevia rebaudiana (Bertoni) raised in vitro. J Appl Res Med Aromat Plants 3:160–167
    • (2016) J Appl Res Med Aromat Plants , vol.3 , pp. 160-167
    • Gupta, P.1    Sharma, S.2    Saxena, S.3
  • 46
    • 84983746039 scopus 로고    scopus 로고
    • Gene transcription and steviol glycoside accumulation in Stevia rebaudiana under polyethylene glycol-induced drought stress in greenhouse cultivation
    • COI: 1:CAS:528:DC%2BC28XitVyisLvO, PID: 27642557
    • Hajihashemi S, Geuns JMC (2016) Gene transcription and steviol glycoside accumulation in Stevia rebaudiana under polyethylene glycol-induced drought stress in greenhouse cultivation. FEBS Open Bio 6:937–944
    • (2016) FEBS Open Bio , vol.6 , pp. 937-944
    • Hajihashemi, S.1    Geuns, J.M.C.2
  • 47
    • 84941949557 scopus 로고    scopus 로고
    • Characterization of Stevia rebaudiana Bertoni polyploids for growth and quality
    • Hegde S, Chavan N, Vasundhara M (2015) Characterization of Stevia rebaudiana Bertoni polyploids for growth and quality. Med Plants 7:188–195
    • (2015) Med Plants , vol.7 , pp. 188-195
    • Hegde, S.1    Chavan, N.2    Vasundhara, M.3
  • 48
    • 84863914032 scopus 로고    scopus 로고
    • Human psychometric and taste receptor responses to steviol glycosides
    • COI: 1:CAS:528:DC%2BC38Xnt1yhs7o%3D, PID: 22616809
    • Hellfritsch C, Brockhoff A, Stahler F, Meyerhof W, Hofmann T (2012) Human psychometric and taste receptor responses to steviol glycosides. J Agric Food Chem 60:6782–6793
    • (2012) J Agric Food Chem , vol.60 , pp. 6782-6793
    • Hellfritsch, C.1    Brockhoff, A.2    Stahler, F.3    Meyerhof, W.4    Hofmann, T.5
  • 49
    • 85067900188 scopus 로고    scopus 로고
    • Controlled elicitation increases steviol glycosides (SGs) content and gene expression-associated to biosynthesis of SGs in Stevia rebaudiana B. cv. Morita II
    • COI: 1:CAS:528:DC%2BC1MXht1Kgur%2FF
    • Hernandez MC, Feregrino-Perez A, Pérez Ramírez I, Ocampo-Velázquez R, Rico-García E, Pacheco I, Guevara-Gonzalez R (2019) Controlled elicitation increases steviol glycosides (SGs) content and gene expression-associated to biosynthesis of SGs in Stevia rebaudiana B. cv. Morita II. Ind Crop Prod 139:111479
    • (2019) Ind Crop Prod , vol.139 , pp. 111479
    • Hernandez, M.C.1    Feregrino-Perez, A.2    Pérez Ramírez, I.3    Ocampo-Velázquez, R.4    Rico-García, E.5    Pacheco, I.6    Guevara-Gonzalez, R.7
  • 50
    • 33745189198 scopus 로고    scopus 로고
    • Spatial organisation of four enzymes from Stevia rebaudiana that are involved in steviol glycoside synthesis
    • COI: 1:CAS:528:DC%2BD28XlvFaisbk%3D, PID: 16786291
    • Humphrey TV, Richman AS, Menassa R, Brandle JE (2006) Spatial organisation of four enzymes from Stevia rebaudiana that are involved in steviol glycoside synthesis. Plant Mol Biol 61:47–62
    • (2006) Plant Mol Biol , vol.61 , pp. 47-62
    • Humphrey, T.V.1    Richman, A.S.2    Menassa, R.3    Brandle, J.E.4
  • 52
    • 84928253802 scopus 로고    scopus 로고
    • Secondary metabolite production in callus cultures of Stevia rebaudiana Bertoni
    • COI: 1:CAS:528:DC%2BC3MXhsV2is7rK
    • Janarthanam B, Gopalakrishnan M, Sekar T (2010) Secondary metabolite production in callus cultures of Stevia rebaudiana Bertoni. Bangladesh J Sci Ind Res 45:243–248
    • (2010) Bangladesh J Sci Ind Res , vol.45 , pp. 243-248
    • Janarthanam, B.1    Gopalakrishnan, M.2    Sekar, T.3
  • 53
    • 85105498222 scopus 로고    scopus 로고
    • Preliminary studies on Stevia rebaudiana Bertoni plants cultivated under the field conditions of Southern Poland
    • Kąkol E, Capecka E, Michalec Ż, Libik-Konieczny M, Dziurka M (2014) Preliminary studies on Stevia rebaudiana Bertoni plants cultivated under the field conditions of Southern Poland. Int J Sci Res 3:1–2
    • (2014) Int J Sci Res , vol.3 , pp. 1-2
    • Kąkol, E.1    Capecka, E.2    Michalec, Ż.3    Libik-Konieczny, M.4    Dziurka, M.5
  • 55
    • 79951514145 scopus 로고    scopus 로고
    • The antioxidant activity and the bioactive compound content of Stevia rebaudiana water extracts
    • COI: 1:CAS:528:DC%2BC3MXhvFKgsrw%3D
    • Kim IS, Yang M, Lee OH, Kang SN (2011) The antioxidant activity and the bioactive compound content of Stevia rebaudiana water extracts. LWT 44:1328–1332
    • (2011) LWT , vol.44 , pp. 1328-1332
    • Kim, I.S.1    Yang, M.2    Lee, O.H.3    Kang, S.N.4
  • 56
    • 85065811304 scopus 로고    scopus 로고
    • Overexpression of SrUGT76G1 in Stevia alters major steviol glycosides composition towards improved quality
    • COI: 1:CAS:528:DC%2BC1MXpslCqtr0%3D, PID: 30569490
    • Kim MJ, Zheng J, Liao MH, Jang IC (2019) Overexpression of SrUGT76G1 in Stevia alters major steviol glycosides composition towards improved quality. Plant Biotechnol J 17:1037–1047
    • (2019) Plant Biotechnol J , vol.17 , pp. 1037-1047
    • Kim, M.J.1    Zheng, J.2    Liao, M.H.3    Jang, I.C.4
  • 58
    • 84942774964 scopus 로고    scopus 로고
    • Metabolic engineering of the Stevia rebaudiana ent-kaurene biosynthetic pathway in recombinant Escherichia coli
    • COI: 1:CAS:528:DC%2BC2MXhsFygt7rL, PID: 26392384
    • Kong MK, Kang H-J, Kim JH, Oh SH, Lee PC (2015) Metabolic engineering of the Stevia rebaudiana ent-kaurene biosynthetic pathway in recombinant Escherichia coli. J Biotechnol 214:95–102
    • (2015) J Biotechnol , vol.214 , pp. 95-102
    • Kong, M.K.1    Kang, H.-J.2    Kim, J.H.3    Oh, S.H.4    Lee, P.C.5
  • 59
    • 84155180843 scopus 로고    scopus 로고
    • A comprehensive analysis of fifteen genes of steviol glycosides biosynthesis pathway in Stevia rebaudiana (Bertoni)
    • Kumar H, Kaul K, Gupta SB, Kaul VK, Kumar S (2012) A comprehensive analysis of fifteen genes of steviol glycosides biosynthesis pathway in Stevia rebaudiana (Bertoni). Gene 492:276–284
    • (2012) Gene , vol.492 , pp. 276-284
    • Kumar, H.1    Kaul, K.2    Gupta, S.B.3    Kaul, V.K.4    Kumar, S.5
  • 60
    • 84949194698 scopus 로고    scopus 로고
    • Stevioside glycosides from in vitro cultures of Stevia rebaudiana and antimicrobial assay
    • Kumari M, Chandra S (2015) Stevioside glycosides from in vitro cultures of Stevia rebaudiana and antimicrobial assay. Braz J Bot 38:761–770
    • (2015) Braz J Bot , vol.38 , pp. 761-770
    • Kumari, M.1    Chandra, S.2
  • 61
    • 84857272396 scopus 로고    scopus 로고
    • Yield, quality and water consumption of Stevia rebaudiana Bertoni grown under different irrigation regimes in Southern Italy
    • Lavini A, Riccardi M, Pulvento C, De Luca S, Scamosci M, d’Andria R (2008) Yield, quality and water consumption of Stevia rebaudiana Bertoni grown under different irrigation regimes in Southern Italy. Ital J Agron 2:135–143
    • (2008) Ital J Agron , vol.2 , pp. 135-143
    • Lavini, A.1    Riccardi, M.2    Pulvento, C.3    De Luca, S.4    Scamosci, M.5    d’Andria, R.6
  • 62
    • 84856221678 scopus 로고    scopus 로고
    • Stevia rebaudiana Bertoni, source of a high-potency natural sweetener: a comprehensive review on the biochemical, nutritional and functional aspects
    • COI: 1:CAS:528:DC%2BC38XhsFKisLo%3D, PID: 29243591
    • Lemus-Mondaca R, Vega-Gálvez A, Zura-Bravo L, Ah-Hen K (2012) Stevia rebaudiana Bertoni, source of a high-potency natural sweetener: a comprehensive review on the biochemical, nutritional and functional aspects. Food Chem 132:1121–1132
    • (2012) Food Chem , vol.132 , pp. 1121-1132
    • Lemus-Mondaca, R.1    Vega-Gálvez, A.2    Zura-Bravo, L.3    Ah-Hen, K.4
  • 63
    • 84961169676 scopus 로고    scopus 로고
    • Stevia rebaudiana leaves: effect of drying process temperature on bioactive components, antioxidant capacity and natural sweeteners
    • COI: 1:CAS:528:DC%2BC2MXitVWrtbvJ, PID: 26650384
    • Lemus-Mondaca R, Ah-Hen K, Vega-Gálvez A, Honores C, Moraga NO (2016) Stevia rebaudiana leaves: effect of drying process temperature on bioactive components, antioxidant capacity and natural sweeteners. Plant Foods Hum Nutr 71:49–56
    • (2016) Plant Foods Hum Nutr , vol.71 , pp. 49-56
    • Lemus-Mondaca, R.1    Ah-Hen, K.2    Vega-Gálvez, A.3    Honores, C.4    Moraga, N.O.5
  • 65
    • 85062948528 scopus 로고    scopus 로고
    • Salt stress-induced changes in in vitro cultured Stevia rebaudiana Bertoni: effect on metabolite contents, antioxidant capacity and expression of steviol glycosides-related biosynthetic genes
    • COI: 1:CAS:528:DC%2BC1MXms1GksL4%3D
    • Lucho SR, do Amaral MN, Auler PA, Bianchi VJ, María Ángeles Ferrer MA, Calderón AA, Bolacel Braga EJ (2019) Salt stress-induced changes in in vitro cultured Stevia rebaudiana Bertoni: effect on metabolite contents, antioxidant capacity and expression of steviol glycosides-related biosynthetic genes. J Plant Growth Regul 38:1341–1353
    • (2019) J Plant Growth Regul , vol.38 , pp. 1341-1353
    • Lucho, S.R.1    do Amaral, M.N.2    Auler, P.A.3    Bianchi, V.J.4    María Ángeles Ferrer, M.A.5    Calderón, A.A.6    Bolacel Braga, E.J.7
  • 67
    • 84923359539 scopus 로고    scopus 로고
    • Enhanced production of steviol glycosides in mycorrhizal plants: a concerted effect of arbuscular mycorrhizal symbiosis on transcription of biosynthetic genes
    • COI: 1:CAS:528:DC%2BC2MXjt1antLc%3D, PID: 25734328
    • Mandal S, Upadhyay S, Singh VP, Kapoor R (2015) Enhanced production of steviol glycosides in mycorrhizal plants: a concerted effect of arbuscular mycorrhizal symbiosis on transcription of biosynthetic genes. Plant Physiol Biochem 89:100–106
    • (2015) Plant Physiol Biochem , vol.89 , pp. 100-106
    • Mandal, S.1    Upadhyay, S.2    Singh, V.P.3    Kapoor, R.4
  • 68
    • 84982296367 scopus 로고    scopus 로고
    • Establishment of highly efficient agrobacterium rhizogenes-mediated transformation for Stevia rebaudiana Bertoni explants
    • COI: 1:CAS:528:DC%2BC28Xhtlejt7fN
    • Michalec-Warzecha Ż, Pistelli L, D’Angiolillo F, Libik-Konieczny M (2016) Establishment of highly efficient agrobacterium rhizogenes-mediated transformation for Stevia rebaudiana Bertoni explants. Acta Biol Cracov Ser Bot 58:113–118
    • (2016) Acta Biol Cracov Ser Bot , vol.58 , pp. 113-118
    • Michalec-Warzecha, Ż.1    Pistelli, L.2    D’Angiolillo, F.3    Libik-Konieczny, M.4
  • 70
    • 79955603749 scopus 로고    scopus 로고
    • UDP-dependent glycosyltransferases involved in the biosynthesis of steviol glycosides
    • COI: 1:CAS:528:DC%2BC3MXlvVaisLw%3D, PID: 21477883
    • Mohamed A, Ceunen S, Geuns J, Van den Ende W, De Ley M (2011) UDP-dependent glycosyltransferases involved in the biosynthesis of steviol glycosides. J Plant Physiol 168:1136–1141
    • (2011) J Plant Physiol , vol.168 , pp. 1136-1141
    • Mohamed, A.1    Ceunen, S.2    Geuns, J.3    Van den Ende, W.4    De Ley, M.5
  • 71
    • 84878242196 scopus 로고    scopus 로고
    • Determination of six steviol glycosides of Stevia rebaudiana (Bertoni) from different geographical origin by LC-ESI-MS/MS
    • COI: 1:CAS:528:DC%2BC3sXps1Ggsro%3D, PID: 23790843
    • Montoro P, Molfetta I, Maldini M, Ceccarini L, Piacente S, Pizza C, Macchia M (2013) Determination of six steviol glycosides of Stevia rebaudiana (Bertoni) from different geographical origin by LC-ESI-MS/MS. Food Chem 141:745–753
    • (2013) Food Chem , vol.141 , pp. 745-753
    • Montoro, P.1    Molfetta, I.2    Maldini, M.3    Ceccarini, L.4    Piacente, S.5    Pizza, C.6    Macchia, M.7
  • 72
    • 85078894082 scopus 로고    scopus 로고
    • Redesign and reconstruction of a steviol- biosynthetic pathway for enhanced production of steviol in Escherichia coli
    • (,),.,:,., https://doi.org/10.1186/s12934-020-1291-x
    • Moon JH, Lee K, Lee JH, Lee PC (2020) Redesign and reconstruction of a steviol- biosynthetic pathway for enhanced production of steviol in Escherichia coli. Microb Cell Factories 19:20. 10.1186/s12934-020-1291-x
    • (2020) Microb Cell Factories , vol.19
    • Moon, J.H.1    Lee, K.2    Lee, J.H.3    Lee, P.C.4
  • 73
    • 79959232302 scopus 로고    scopus 로고
    • Study on chemical composition and biological activities of essential oil and extracts from Stevia rebaudiana Bertoni leaves
    • COI: 1:CAS:528:DC%2BC3MXnslOktbo%3D
    • Muanda FN, Soulimani R, Diop B, Dicko A (2011) Study on chemical composition and biological activities of essential oil and extracts from Stevia rebaudiana Bertoni leaves. LWT 44:1865–1872
    • (2011) LWT , vol.44 , pp. 1865-1872
    • Muanda, F.N.1    Soulimani, R.2    Diop, B.3    Dicko, A.4
  • 74
    • 0142178350 scopus 로고
    • Variation in the main glycosides of stevia (Stevia rebaudiana Bertoni)
    • Nakamura S, Tamura Y (1995) Variation in the main glycosides of stevia (Stevia rebaudiana Bertoni). Jpn J Trop Agric 29:109–115
    • (1995) Jpn J Trop Agric , vol.29 , pp. 109-115
    • Nakamura, S.1    Tamura, Y.2
  • 76
    • 79955532645 scopus 로고    scopus 로고
    • Characterization of novel steviol glycosides from leaves of Stevia rebaudiana Morita
    • COI: 1:CAS:528:DC%2BC3cXhtVyltL7L
    • Ohta M, Sasa S, Inoue A, Tamai T, Fujita I, Morita K, Matsuura F (2010) Characterization of novel steviol glycosides from leaves of Stevia rebaudiana Morita. J Appl Glycosci 57:199–209
    • (2010) J Appl Glycosci , vol.57 , pp. 199-209
    • Ohta, M.1    Sasa, S.2    Inoue, A.3    Tamai, T.4    Fujita, I.5    Morita, K.6    Matsuura, F.7
  • 78
    • 84884975916 scopus 로고    scopus 로고
    • Effect of decapitation and nutrient applications on shoot branching, yield, and accumulation of secondary metabolites in leaves of Stevia rebaudiana Bertoni
    • COI: 1:CAS:528:DC%2BC3sXht1Sjur3M, PID: 23910992
    • Pal PK, Prasad R, Pathania V (2013) Effect of decapitation and nutrient applications on shoot branching, yield, and accumulation of secondary metabolites in leaves of Stevia rebaudiana Bertoni. J Plant Physiol 170:1526–1535
    • (2013) J Plant Physiol , vol.170 , pp. 1526-1535
    • Pal, P.K.1    Prasad, R.2    Pathania, V.3
  • 79
    • 84874954228 scopus 로고    scopus 로고
    • Plant tissue culture of Stevia rebaudiana (Bertoni): A review
    • Pande SS, Gupta P (2013) Plant tissue culture of Stevia rebaudiana (Bertoni): A review. J Pharmacogn Phytother 5:26–33
    • (2013) J Pharmacogn Phytother , vol.5 , pp. 26-33
    • Pande, S.S.1    Gupta, P.2
  • 80
    • 85042129545 scopus 로고    scopus 로고
    • Effect of salinity and drought stress on growth parameters, glycoside content and expression level of vital genes in steviol glycosides biosynthesis pathway of Stevia rebaudiana (Bertoni)
    • COI: 1:CAS:528:DC%2BC28Xhtl2isLrO
    • Pandey M, Chikara SK (2015) Effect of salinity and drought stress on growth parameters, glycoside content and expression level of vital genes in steviol glycosides biosynthesis pathway of Stevia rebaudiana (Bertoni). Int J Genet 7:153–160
    • (2015) Int J Genet , vol.7 , pp. 153-160
    • Pandey, M.1    Chikara, S.K.2
  • 81
    • 84975140597 scopus 로고    scopus 로고
    • Meeting the challenge of stevioside production in the hairy roots of Stevia rebaudiana by probing the underlying process
    • COI: 1:CAS:528:DC%2BC28XhtVWlu7vF
    • Pandey H, Pandey P, Pandey SS, Singh S, Banerjee S (2016) Meeting the challenge of stevioside production in the hairy roots of Stevia rebaudiana by probing the underlying process. Plant Cell Tissue Organ Cult 126:511–521
    • (2016) Plant Cell Tissue Organ Cult , vol.126 , pp. 511-521
    • Pandey, H.1    Pandey, P.2    Pandey, S.S.3    Singh, S.4    Banerjee, S.5
  • 82
    • 84907211048 scopus 로고    scopus 로고
    • Influence of drying method on steviol glycosides and antioxidants in Stevia rebaudiana leaves
    • COI: 1:CAS:528:DC%2BC2cXhsFCnsrzF, PID: 25442516
    • Periche A, Castelló ML, Heredia A, Escriche I (2015) Influence of drying method on steviol glycosides and antioxidants in Stevia rebaudiana leaves. Food Chem 172:1–6
    • (2015) Food Chem , vol.172 , pp. 1-6
    • Periche, A.1    Castelló, M.L.2    Heredia, A.3    Escriche, I.4
  • 85
    • 85062938567 scopus 로고    scopus 로고
    • Impact of glycine betaine on salinity tolerance of stevia (Stevia rebaudiana Bertoni) under in vitro condition
    • Rameeh V, Gerami M, Omran VG, Ghavampour S (2017) Impact of glycine betaine on salinity tolerance of stevia (Stevia rebaudiana Bertoni) under in vitro condition. Cercetări Agronomice Moldova 3:95–105
    • (2017) Cercetări Agronomice Moldova , vol.3 , pp. 95-105
    • Rameeh, V.1    Gerami, M.2    Omran, V.G.3    Ghavampour, S.4
  • 86
    • 33646894448 scopus 로고    scopus 로고
    • Cultivation of stevia (Stevia rebaudiana): a comprehensive review
    • Ramesh K, Singh V, Megeji NW (2006) Cultivation of stevia (Stevia rebaudiana): a comprehensive review. Adv Agron 89:137–177
    • (2006) Adv Agron , vol.89 , pp. 137-177
    • Ramesh, K.1    Singh, V.2    Megeji, N.W.3
  • 88
    • 12744278046 scopus 로고    scopus 로고
    • Functional genomics uncovers three glucosyltransferases involved in the synthesis of the major sweet glucosides of Stevia rebaudiana
    • COI: 1:CAS:528:DC%2BD2MXhtVWjsLY%3D, PID: 15610349
    • Richman A, Swanson A, Humphrey T, Chapman R, McGarvey B, Pocs R, Brandle J (2005) Functional genomics uncovers three glucosyltransferases involved in the synthesis of the major sweet glucosides of Stevia rebaudiana. Plant J 41:56–67
    • (2005) Plant J , vol.41 , pp. 56-67
    • Richman, A.1    Swanson, A.2    Humphrey, T.3    Chapman, R.4    McGarvey, B.5    Pocs, R.6    Brandle, J.7
  • 89
    • 85040827064 scopus 로고    scopus 로고
    • Rosales C, Brenes J, Salas K, Arce-Solano S, Abdelnour-Esquivel A (2018) Micropropagation of Stevia rebaudiana in temporary immersion systems as an alternative horticultural production method. Rev Chapingo Ser Hortic 24(1)
  • 91
    • 33846913236 scopus 로고    scopus 로고
    • Production of steviosides in ex vitro and in vitro grown Stevia rebaudiana Bertoni
    • COI: 1:CAS:528:DC%2BD2sXitValur8%3D
    • Sekaran T, Giridhar P, Ravishankar GA (2007) Production of steviosides in ex vitro and in vitro grown Stevia rebaudiana Bertoni. J Sci Food Agric 87:420–424
    • (2007) J Sci Food Agric , vol.87 , pp. 420-424
    • Sekaran, T.1    Giridhar, P.2    Ravishankar, G.A.3
  • 92
    • 85044680972 scopus 로고    scopus 로고
    • Stevia (Stevia rebaudiana Bertoni) responses to NaCl stress: Growth, photosynthetic pigments, diterpene glycosides and ion content in root and shoot
    • Shahverdi MA, Omidi H, Tabatabaei SJ (2019) Stevia (Stevia rebaudiana Bertoni) responses to NaCl stress: Growth, photosynthetic pigments, diterpene glycosides and ion content in root and shoot. J Saudi Soc Agric Sci 18:355–360
    • (2019) J Saudi Soc Agric Sci , vol.18 , pp. 355-360
    • Shahverdi, M.A.1    Omidi, H.2    Tabatabaei, S.J.3
  • 93
    • 85029876707 scopus 로고    scopus 로고
    • Molecular dissection of transcriptional reprogramming of steviol glycosides synthesis in leaf tissue during developmental phase transitions in S. rebaudiana Bert [J]
    • PID: 28928460, COI: 1:CAS:528:DC%2BC1cXhtl2lu7jI
    • Singh G, Singh G, Singh P, Parmar R, Paul N, Vashist R, Swarnkar MK, Kumar A, Singh S, Singh AK, Kumar S, Sharma RK (2017) Molecular dissection of transcriptional reprogramming of steviol glycosides synthesis in leaf tissue during developmental phase transitions in S. rebaudiana Bert [J]. Sci Rep 7:11835
    • (2017) Sci Rep , vol.7 , pp. 11835
    • Singh, G.1    Singh, G.2    Singh, P.3    Parmar, R.4    Paul, N.5    Vashist, R.6    Swarnkar, M.K.7    Kumar, A.8    Singh, S.9    Singh, A.K.10    Kumar, S.11    Sharma, R.K.12
  • 94
    • 85105466463 scopus 로고    scopus 로고
    • How to broaden the applicability of the high potency sweeteners steviol glycosides: From enzymatic glycosylation to recombinant production.University of Groningen, Groningen, The Netherlands
    • Spakman D (2015) How to broaden the applicability of the high potency sweeteners steviol glycosides: from enzymatic glycosylation to recombinant production.University of Groningen, Groningen, The Netherlands. 2014 Essay Biomolecular Sciences ID: 199366898
    • (2015) 2014 Essay Biomolecular Sciences ID
    • Spakman, D.1
  • 95
    • 46149087309 scopus 로고    scopus 로고
    • Direct organogenesis from leaf explants of Stevia rebaudiana and cultivation in bioreactor
    • COI: 1:CAS:528:DC%2BD1cXpvVKhsr0%3D
    • Sreedhar R, Venkatachalam L, Thimmaraju R, Neelwarne B, Narayan M, Gokare R (2008) Direct organogenesis from leaf explants of Stevia rebaudiana and cultivation in bioreactor. Biol Plant 52:355–360
    • (2008) Biol Plant , vol.52 , pp. 355-360
    • Sreedhar, R.1    Venkatachalam, L.2    Thimmaraju, R.3    Neelwarne, B.4    Narayan, M.5    Gokare, R.6
  • 96
    • 79953098285 scopus 로고    scopus 로고
    • The food additives inulin and stevioside counteract oxidative stress
    • COI: 1:CAS:528:DC%2BC3MXjvVKnsrc%3D, PID: 21043580
    • Stoyanova S, Geuns J, Hideg É, Van Den Ende W (2011) The food additives inulin and stevioside counteract oxidative stress. Int J Food Sci Nutr 62:207–214
    • (2011) Int J Food Sci Nutr , vol.62 , pp. 207-214
    • Stoyanova, S.1    Geuns, J.2    Hideg, É.3    Van Den Ende, W.4
  • 97
    • 0000089564 scopus 로고
    • Stevioside biosynthesis by callus, root, shoot and rooted-shoot cultures in vitro
    • COI: 1:CAS:528:DyaK38XhvFamt7c%3D
    • Swanson SM, Mahady GB, Beecher CWW (1992) Stevioside biosynthesis by callus, root, shoot and rooted-shoot cultures in vitro. Plant Cell Tissue Organ Cult 28:151–157
    • (1992) Plant Cell Tissue Organ Cult , vol.28 , pp. 151-157
    • Swanson, S.M.1    Mahady, G.B.2    Beecher, C.W.W.3
  • 98
    • 84954962477 scopus 로고
    • Rubusoside (β-D- Glucosyl Ester of 13-O-β-D-Glucosyl-steviol), a sweet principle of Rubus chingii Hu (Rosaceae)
    • COI: 1:CAS:528:DyaL3MXmtFOlt7c%3D
    • Tanaka T, Kohda H, Tanaka O, Chen F-H, Chou W-H, Leu J-L (1981) Rubusoside (β-D- Glucosyl Ester of 13-O-β-D-Glucosyl-steviol), a sweet principle of Rubus chingii Hu (Rosaceae). Agric Biol Chem 45:2165–2166
    • (1981) Agric Biol Chem , vol.45 , pp. 2165-2166
    • Tanaka, T.1    Kohda, H.2    Tanaka, O.3    Chen, F.-H.4    Chou, W.-H.5    Leu, J.-L.6
  • 99
    • 0034641488 scopus 로고    scopus 로고
    • Biosynthesis of the diterpenoid steviol, an ent-kaurene derivative from Stevia rebaudiana Bertoni, via the methylerythritol phosphate pathway
    • Totté N, Charon L, Rohmer M, Compernolle F, Baboeuf I, Geuns J (2000) Biosynthesis of the diterpenoid steviol, an ent-kaurene derivative from Stevia rebaudiana Bertoni, via the methylerythritol phosphate pathway. Tetrahedron Lett 41:6407–6410
    • (2000) Tetrahedron Lett , vol.41 , pp. 6407-6410
    • Totté, N.1    Charon, L.2    Rohmer, M.3    Compernolle, F.4    Baboeuf, I.5    Geuns, J.6
  • 100
    • 85053782848 scopus 로고    scopus 로고
    • Rebaudioside A and other unreported steviol glycoside isomers found in the sweet tea (Rubus suavissimis) leaf
    • COI: 1:CAS:528:DC%2BC1cXhslyqs7nO
    • Uhler B, Yang Z (2018) Rebaudioside A and other unreported steviol glycoside isomers found in the sweet tea (Rubus suavissimis) leaf. Phytochem Lett 28:93–97
    • (2018) Phytochem Lett , vol.28 , pp. 93-97
    • Uhler, B.1    Yang, Z.2
  • 101
    • 84957429577 scopus 로고    scopus 로고
    • Pathway mining-based integration of critical enzyme parts for de novo biosynthesis of steviol glycosides sweetener in Escherichia coli[J]
    • PID: 26584641, COI: 1:CAS:528:DC%2BC2MXhvVyrs7zP
    • Wang J, Li S, Xiong Z, Wang Y (2015) Pathway mining-based integration of critical enzyme parts for de novo biosynthesis of steviol glycosides sweetener in Escherichia coli[J]. Cell Res 26:1–4
    • (2015) Cell Res , vol.26 , pp. 1-4
    • Wang, J.1    Li, S.2    Xiong, Z.3    Wang, Y.4
  • 102
    • 85089184296 scopus 로고    scopus 로고
    • A review of stevia as a potential healthcare product: up-to-date functional characteristics, administrative standards and engineering techniques
    • COI: 1:CAS:528:DC%2BB3cXhsFOht7nN
    • Wang J, Zhao H, Wang Y, Lau H, Zhou W, Chen C, Tan S (2020) A review of stevia as a potential healthcare product: up-to-date functional characteristics, administrative standards and engineering techniques. Trends Food Sci Technol 103:264–281
    • (2020) Trends Food Sci Technol , vol.103 , pp. 264-281
    • Wang, J.1    Zhao, H.2    Wang, Y.3    Lau, H.4    Zhou, W.5    Chen, C.6    Tan, S.7
  • 103
    • 0020675059 scopus 로고
    • Sequence homologous to Agrobacterium rhizogenes TDNA in the genome of uninfected plants
    • COI: 1:CAS:528:DyaL3sXhtVajsL8%3D
    • White FF, Garfinkel DJ, Huffman GA, Gordon MP, Nester EW (1983) Sequence homologous to Agrobacterium rhizogenes TDNA in the genome of uninfected plants. Nature 301:348–350
    • (1983) Nature , vol.301 , pp. 348-350
    • White, F.F.1    Garfinkel, D.J.2    Huffman, G.A.3    Gordon, M.P.4    Nester, E.W.5
  • 104
    • 84856529142 scopus 로고    scopus 로고
    • The leaves of Stevia rebaudiana (Bertoni), their constituents and the analyses thereof: a review
    • PID: 22250765, COI: 1:CAS:528:DC%2BC38Xntlansg%3D%3D
    • Wölwer-Rieck U (2012) The leaves of Stevia rebaudiana (Bertoni), their constituents and the analyses thereof: a review. J Agric Food Chem 60:886–895
    • (2012) J Agric Food Chem , vol.60 , pp. 886-895
    • Wölwer-Rieck, U.1
  • 105
    • 79551469898 scopus 로고    scopus 로고
    • A review on the improvement of stevia [Stevia rebaudiana (Bertoni)]
    • Yadav AK, Singh S, Dhyani D, Ahuja PS (2011) A review on the improvement of stevia [Stevia rebaudiana (Bertoni)]. Can J Plant Sci 91:1–27
    • (2011) Can J Plant Sci , vol.91 , pp. 1-27
    • Yadav, A.K.1    Singh, S.2    Dhyani, D.3    Ahuja, P.S.4
  • 106
    • 0025861571 scopus 로고
    • Examination of steviol glycosides production by hairy root and shoot cultures of Stevia rebaudiana
    • COI: 1:CAS:528:DyaK3MXmt1ynt7o%3D
    • Yamazaki T, Flores HE (1991) Examination of steviol glycosides production by hairy root and shoot cultures of Stevia rebaudiana. J Nat Prod 54:986–992
    • (1991) J Nat Prod , vol.54 , pp. 986-992
    • Yamazaki, T.1    Flores, H.E.2
  • 107
    • 84916604121 scopus 로고    scopus 로고
    • Environmental cues induce changes of steviol glycosides contents and transcription of corresponding biosynthetic genes in Stevia rebaudiana
    • COI: 1:CAS:528:DC%2BC2cXitVyksrnI, PID: 25500454
    • Yang Y, Huang S, Han Y, Yuan H, Gu C, Wang Z (2015) Environmental cues induce changes of steviol glycosides contents and transcription of corresponding biosynthetic genes in Stevia rebaudiana. Plant Physiol Biochem 86:174–180
    • (2015) Plant Physiol Biochem , vol.86 , pp. 174-180
    • Yang, Y.1    Huang, S.2    Han, Y.3    Yuan, H.4    Gu, C.5    Wang, Z.6
  • 108
    • 85012902183 scopus 로고    scopus 로고
    • Impact of blue, red, and far-red light treatments on gene expression and steviol glycoside accumulation in Stevia rebaudiana
    • COI: 1:CAS:528:DC%2BC2sXislOrur0%3D, PID: 28215607
    • Yoneda Y, Nakashima H, Miyasaka J, Ohdoi K, Shimizu H (2017) Impact of blue, red, and far-red light treatments on gene expression and steviol glycoside accumulation in Stevia rebaudiana. Phytochemistry 137:57–65
    • (2017) Phytochemistry , vol.137 , pp. 57-65
    • Yoneda, Y.1    Nakashima, H.2    Miyasaka, J.3    Ohdoi, K.4    Shimizu, H.5
  • 109
    • 84977070918 scopus 로고    scopus 로고
    • Yücesan B, Büyükgöçmen R, Mohammed A, Sameeullah M, Altuğ C, Gürel S, Gürel E (2016) An efficient regeneration system and steviol glycoside analysis of Stevia rebaudiana Bertoni, a source of natural high-intensity sweetener. In Vitro Cell Dev Biol-Plant 52:30–337
  • 110
    • 84879349029 scopus 로고    scopus 로고
    • Effects of salt stress on the growth, physiological responses, and glycoside contents of Stevia rebaudiana Bertoni
    • COI: 1:CAS:528:DC%2BC3sXot1Sqs7g%3D, PID: 23711229
    • Zeng J, Chen A, Li D, Yi B, Wu W (2013) Effects of salt stress on the growth, physiological responses, and glycoside contents of Stevia rebaudiana Bertoni. J Agric Food Chem 61:5720–5726
    • (2013) J Agric Food Chem , vol.61 , pp. 5720-5726
    • Zeng, J.1    Chen, A.2    Li, D.3    Yi, B.4    Wu, W.5
  • 111
    • 85064677543 scopus 로고    scopus 로고
    • Induction, identification and characterization of polyploidy in Stevia rebaudiana Bertoni
    • COI: 1:CAS:528:DC%2BC1MXitlWksLY%3D
    • Zhang H, An S, Hu J, Lin Z, Liu X, Bao H, Chen R (2018) Induction, identification and characterization of polyploidy in Stevia rebaudiana Bertoni. Plant Biotechnol (Tsukuba) 35:81–86
    • (2018) Plant Biotechnol (Tsukuba) , vol.35 , pp. 81-86
    • Zhang, H.1    An, S.2    Hu, J.3    Lin, Z.4    Liu, X.5    Bao, H.6    Chen, R.7
  • 112
    • 85095954836 scopus 로고    scopus 로고
    • Characterizing glycosyltransferases by a combination of sequencing platforms applied to the leaf tissues of Stevia rebaudiana
    • COI: 1:CAS:528:DC%2BB3cXitlygtLjJ, PID: 33187479
    • Zhang S, Liu Q, Lyu C, Chen J, Xiao R, Chen J, Yang Y, Zhang H, Hou K, Wu W (2020) Characterizing glycosyltransferases by a combination of sequencing platforms applied to the leaf tissues of Stevia rebaudiana. BMC Genomics 21:794
    • (2020) BMC Genomics , vol.21 , pp. 794
    • Zhang, S.1    Liu, Q.2    Lyu, C.3    Chen, J.4    Xiao, R.5    Chen, J.6    Yang, Y.7    Zhang, H.8    Hou, K.9    Wu, W.10
  • 113
    • 84878950920 scopus 로고    scopus 로고
    • Methylerythritol phosphate pathway of isoprenoid biosynthesis
    • COI: 1:CAS:528:DC%2BC3sXhtFOqsr3J, PID: 23746261
    • Zhao L, Chang WC, Xiao Y, Liu HW, Liu P (2013) Methylerythritol phosphate pathway of isoprenoid biosynthesis. Annu Rev Biochem 82:497–530
    • (2013) Annu Rev Biochem , vol.82 , pp. 497-530
    • Zhao, L.1    Chang, W.C.2    Xiao, Y.3    Liu, H.W.4    Liu, P.5
  • 114


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