Determination of six steviol glycosides of Stevia rebaudiana (Bertoni) from different geographical origin by LC-ESI-MS/MS

Food Chemistry

Volumn 141, Issue 2, 2013, Pages 745-753

  Montoro, Paola ^a   Molfetta, Ilaria ^b   Maldini, Mariateresa ^a   Ceccarini, Lucia ^b   Piacente, Sonia ^a   Pizza, Cosimo ^a   Macchia, Mario ^b  

^a UNIVERSITY OF SALERNO   (Italy)

^b UNIVERSITY OF PISA   (Italy)

Author keywords

LC ESI MS MS; Quantitative analyzes; Stevia rebaudiana; Steviol glycosides

Indexed keywords

LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRINCIPAL COMPONENT ANALYSIS; QUALITY CONTROL; SEED; SUGAR SUBSTITUTES; SUGARS;

GENOTYPIC DIFFERENCES; GEOGRAPHIC ORIGINS; GEOGRAPHICAL ORIGINS; LC-ESI/MS/MS; QUANTITATIVE ANALYZES; STEVIA REBAUDIANA; STEVIOL GLYCOSIDES; TANDEM MASS SPECTROMETRY;

GLYCOSIDES;

PLANT GLYCOSIDE; REBAUDIOSIDE A; REBAUDIOSIDE B; REBAUDIOSIDE C; STEVIOL; STEVIOLBIOSIDE; STEVIOSIDE; UNCLASSIFIED DRUG;

ARTICLE; BRAZIL; CALIBRATION; CONCENTRATION (PARAMETERS); DRUG DETERMINATION; ELECTROSPRAY MASS SPECTROMETRY; GENE IDENTIFICATION; GEOGRAPHIC ORIGIN; ITALY; LIQUID CHROMATOGRAPHY; NONHUMAN; PLANT SEED; PRINCIPAL COMPONENT ANALYSIS; QUANTITATIVE ANALYSIS; SPECIES CULTIVATION; STEVIA; SWEETNESS; TANDEM MASS SPECTROMETRY;

STEVIA REBAUDIANA;

EID: 84878242196     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2013.03.041     Document Type: Article

References (26)

1. Brandle, J. U. S. (2001). Patent No. 6255557. .
2. Cacciola, F., Delmonte, P., Jaworska, K., Dugo, P., Mondello, L., & Rader, J. I. (2011). Employing ultra high pressure liquid chromatography as the second dimension in a comprehensive two-dimensional system for analysis of Stevia rebaudiana extracts. Journal of Chromatography, A, 1218(15), 2012-2018.
3. Chan, P., Tomlinson, B., Chen, Y., Liu, J., Hsieh, M., & Cheng, J. (2000). A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. British Journal of Clinical Pharmacology, 50(4), 215-220.
4. Chatsudthipong, V., & Muanprasat, C. (2009). Stevioside and related compounds: Therapeutic benefits beyond sweetness. Pharmacology and Therapeutics, 121(1), 41-54.
5. Dozono, F. (1993). US Patent No. 5262161. .
6. Gardana, C., Scaglianti, M., & Simonetti, P. (2010). Evaluation of steviol and its glycosides in Stevia rebaudiana leaves and commercial sweetener by ultra-highperformance liquid chromatography-mass spectrometry. Journal of Chromatography, A, 1217(9), 1463-1470.
7. Geuns, J. M. C. (2007) Stevia and steviol glycosides. Properties, techniques, uses, exposure, toxicology, pharmacological effects, EUPRINT.
8. Granato, D., Katayama, F. C. U., & Castro, I. A. (2012). Characterization of red wines from South America based on sensory properties and antioxidant activity. Journal of the Science of Food and Agriculture, 92, 526-533.
9. Hearn, L. K., & Subedi, P. P. (2009). Determining levels of steviol glycosides in the leaves of Stevia rebaudiana by near infrared reflectance spectroscopy. Journal of Food Composition and Analysis, 22(2), 165-168.
10. Quality Guidelines: Validation of analytical procedures - Text and methodology (ICH Q2), London, European Medicines Agency, 1995. Available at: http://www.emea.europa.eu/pdfs/human/ich/038195en.pdf.
11. Jaitak, V., Gupta, A. P., Kaul, V. K., & Ahuja, P. S. (2008). Validated high-performance thin-layer chromatography method for steviol glycosides in Stevia rebaudiana. Journal of Pharmaceutical and Biomedical Analysis, 47, 790-794.
12. Jeppesen, P. B., Gregersen, S., Alstrupp, K. K., & Hermansenn, K. (2002). Stevioside induces antihyperglyc (Pubitemid 34184204)
13. Jeppesen, P. B., Gregersen, S., Rolfsen, S. E. D., Jepsen, M., Colombo, M., Agger, A., et al. (2003). Antihyperglycemic and blood pressure-reducing effects of stevioside in the diabetic Goto-Kakizaki rat. Metabolism, Clinical and Experimental, 52(3), 372-378. (Pubitemid 36401684)
14. Joint FAO/WHO Expert Committee on Food Additives (JECFA), Compendium of food additive specifications. Monograph 10. Steviol glycosides. Available at: http://www.fao.org/ag/agn/jecfaadditives/specs/monograph10/additive-442-m10.pdf.
15. Kitteringham, N. R., Jenkins, R. E., Lane, C. S., Elliott, Vi. L., & Park, B. K. (2009). Multiple reaction monitoring for quantitative biomarker analysis in proteomics and metabolomics. Journal of Chromatography, B: Analytical Technologies in the Biomedical and Life Sciences, 877(13), 1229-1239.
16. Kolb, N., Herrera, J. L., Ferreyra, D. J., & Uliana, R. F. (2001). Analysis of sweet diterpene glycosides from Stevia rebaudiana: Improved HPLC method. Journal of Agricultural and Food Chemistry, 49(10), 4538-4541. (Pubitemid 32988682)
17. Mari, A., Montoro, P., Pizza, C., & Piacente, S. (2012). Liquid chromatography tandem mass spectrometry determination of chimica markers and principal component analysis of Vitex agnus-castus L. fruits (Verbenaceae) and derived food supplements. Journal of Pharmaceutical and Biomedical Analysis, 70, 224-230.
18. Montoro, P., Maldini, M., Russo, M., Postorino, S., Piacente, S., & Pizza, C. (2011). Metabolic profiling of roots of liquorice (Glycyrrhiza glabra) from different geographical areas by ESI/MS/MS and determination of major metabolites by LC-ESI/MS and LC-ESI/MS/MS. Journal of Pharmaceutical and Biomedical Analysis, 54(3), 535-544.
19. Phillips, K. C. (1989). In T. H. Grenby (Ed.), Developments in sweeteners (3th ed.), Elsevier: London, pp. 1-43.
20. 1H NMR spectroscopy. Journal of Agricultural and Food Chemistry, 59(9), 4378-4384.
21. Ramesh, K., Virendra, S., & Nima, M. W. (2006). Cultivation of Stevia (Stevia rebaudiana (Bert.) Bertoni): A comprehensive review. Advance in Agronomy, 89, 137-177. (Pubitemid 43786237)
22. Takahashi, K., Matsuda, M., Ohashi, K., Taniguchi, K., Nakagomi, O., Abe, Y., et al. (2001). Analysis of anti-rotavirus activity of extract from Stevia rebaudiana. Antiviral Research, 49(1), 15-24. (Pubitemid 32146575)
23. Tanaka, O. (1982). Steviol-glycosides: New natural sweeteners. TrAC, Trends in Analytical Chemistry, 1(11), 246-248.
24. White, J. R., Kramer, J., Campbell, R. K., & Bernstein, R. (1994). Oral use of a topical preparation containing an extract of Stevia rebaudiana and the chrysanthemum flower in the management of hyperglycemia. Diabetes-Care, 17(8), 940-941.
25. Woelwer-Rieck, U., Lankes, C., Wawrzun, A., & Wuest, M. (2010). Improved HPLC method for the evaluation of the major steviol glycosides in leaves of Stevia rebaudiana. European Food Research and Technology, 231(4), 581-588.
26. Xi, Y., Yamaguchi, T., Sato, M., & Takeuchi, M. (1998). Study on Stevia rebaudiana for antioxidant activity. II. Antioxidant mechanism of Stevia rebaudiana extract and antioxidant activity of inorganic salts. Nippon Shokuhin Kagaku Kaishi, 45(5), 317-322. (Pubitemid 128681599)