Metabolic engineering of the Stevia rebaudiana ent-kaurene biosynthetic pathway in recombinant Escherichia coli

Journal of Biotechnology

Volumn 214, Issue , 2015, Pages 95-102

  Kong, Min Kyung ^a   Kang, Hyun Jun ^a   Kim, Jin Ho ^a   Oh, Soon Hwan ^a   Lee, Pyung Cheon ^a  

^a Ajou University   (South Korea)

Author keywords

Diterpene; Ent Kaurene; Metabolic engineering; Stevia rebaudiana

Indexed keywords

ESCHERICHIA COLI; METABOLIC ENGINEERING; METABOLISM; STRAIN; SUGAR SUBSTITUTES; SUGARS;

DITERPENES; ENT-KAURENE; FARNESYL DIPHOSPHATE SYNTHASE; GERANYLGERANYL DIPHOSPHATE; ISOPENTENYL DIPHOSPHATE ISOMERASE (IDI); RECOMBINANT ESCHERICHIA COLI; RHODOBACTER SPHAEROIDES; STEVIA REBAUDIANA;

GLYCOSIDES;

1 DEOXYXYLULOSE 5 PHOSPHATE SYNTHASE; COPALYL DIPHOSPHATE SYNTHASE; ENT KAURENE SYNTHASE; FARNESYL TRANS TRANSFERASE; GLYCEROL; ISOPENTENYL DIPHOSPHATE DELTA ISOMERASE; KAURENE DERIVATIVE; SYNTHETASE; UNCLASSIFIED DRUG; KAURANE DERIVATIVE; RECOMBINANT PROTEIN; VEGETABLE PROTEIN;

ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BATCH FERMENTATION; BIOREACTOR; BIOTECHNOLOGICAL PRODUCTION; CARBON SOURCE; CONTROLLED STUDY; DRUG SYNTHESIS; ESCHERICHIA COLI; EXPRESSION VECTOR; GENE OVEREXPRESSION; GENETIC RECOMBINATION; HOST; IN VITRO STUDY; ION MONITORING; MASS FRAGMENTOGRAPHY; METABOLIC ENGINEERING; NONHUMAN; PRECURSOR; PRIORITY JOURNAL; RHODOBACTER SPHAEROIDES; STEVIA REBAUDIANA; FERMENTATION; GENETICS; METABOLISM; PROCEDURES; STEVIA;

DITERPENES, KAURANE; ESCHERICHIA COLI; FERMENTATION; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; PLANT PROTEINS; RECOMBINANT PROTEINS; STEVIA;

EID: 84942774964     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2015.09.016     Document Type: Article

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