Redesign and reconstruction of a steviol-biosynthetic pathway for enhanced production of steviol in Escherichia coli

Microbial Cell Factories

Volumn 19, Issue 1, 2020, Pages

  Moon, Jun Ho ^a   Lee, Kunjoong ^a   Lee, Jun Ho ^a   Lee, Pyung Cheon ^a  

^a Ajou University   (South Korea)

Author keywords

Kaurene; Kaurenoic acid; Metabolic engineering; Steviol

Indexed keywords

COPALYL DIPHOSPHATE SYNTHASE; FARNESYL TRANS TRANSFERASE; FUSION PROTEIN; KAURENE SYNTHASE; KAURENOIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; STEVIOL; SYNTHETASE; UNCLASSIFIED DRUG; UTRCYP714A2 ATCPR2 FUSION PROTEIN; ARABIDOPSIS PROTEIN; CYTOCHROME P450; ENT-KAURENE OXIDASE; ENT-KAURENE SYNTHETASE A; KAURANE DERIVATIVE; PLANT PROTEIN; RECOMBINANT PROTEIN; TRANSFERASE;

5' UNTRANSLATED REGION; AMINO TERMINAL SEQUENCE; ARABIDOPSIS THALIANA; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BATCH FERMENTATION; BIOREACTOR FERMENTATION; BIOSYNTHESIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; ESCHERICHIA COLI; FERMENTATION TECHNIQUE; FLASK FERMENTATION; GDHA GENE; GENE DELETION; GENE OVEREXPRESSION; GENETIC ENGINEERING; METABOLIC ENGINEERING; NONHUMAN; OXIDATION REDUCTION REACTION; PROTEIN EXPRESSION; SYNTHETIC BIOLOGY; ARABIDOPSIS; BATCH CELL CULTURE; BIOTECHNOLOGY; FERMENTATION; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PROCEDURES; PROTEIN ENGINEERING; STEVIA;

ALKYL AND ARYL TRANSFERASES; ARABIDOPSIS; ARABIDOPSIS PROTEINS; BATCH CELL CULTURE TECHNIQUES; BIOTECHNOLOGY; CYTOCHROME P-450 ENZYME SYSTEM; DITERPENES, KAURANE; ESCHERICHIA COLI; FARNESYLTRANSTRANSFERASE; FERMENTATION; METABOLIC ENGINEERING; PLANT PROTEINS; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; STEVIA;

EID: 85078894082     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-020-1291-x     Document Type: Article

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