-
1
-
-
85038408228
-
Empagliflozin limits myocardial infarction in vivo and cell death in vitro: role of STAT3, mitochondria, and redox aspects
-
29311992
-
Andreadou I., Efentakis P., Balafas E., Togliatto G., Davos C. H., Varela A., et al. (2017). Empagliflozin limits myocardial infarction in vivo and cell death in vitro: role of STAT3, mitochondria, and redox aspects. Front. Physiol. 8:1077. 10.3389/fphys.2017.01077 29311992
-
(2017)
Front. Physiol
, vol.8
, Issue.1077
-
-
Andreadou, I.1
Efentakis, P.2
Balafas, E.3
Togliatto, G.4
Davos, C.H.5
Varela, A.6
-
2
-
-
77956320283
-
Inflammation determines the pro-adhesive properties of high extracellular D-glucose in human endothelial cells in vitro and rat microvessels in vivo
-
20386708
-
Azcutia V., Abu-Taha M., Romacho T., Vázquez-Bella M., Matesanz N., Luscinskas F. W., et al. (2010). Inflammation determines the pro-adhesive properties of high extracellular D-glucose in human endothelial cells in vitro and rat microvessels in vivo. PLoS One 5:e10091. 10.1371/journal.pone.0010091 20386708
-
(2010)
PLoS One
, vol.5
, Issue.e10091
-
-
Azcutia, V.1
Abu-Taha, M.2
Romacho, T.3
Vázquez-Bella, M.4
Matesanz, N.5
Luscinskas, F.W.6
-
3
-
-
47249152693
-
+-exchanger causes regression of hypertrophy, heart failure, and ionic and electrophysiological remodelling
-
18493245
-
+-exchanger causes regression of hypertrophy, heart failure, and ionic and electrophysiological remodelling. Br. J. Pharmacol. 154 1266–1275. 10.1038/bjp.2008.189 18493245
-
(2008)
Br. J. Pharmacol
, vol.154
, pp. 1266-1275
-
-
Baartscheer, A.1
Hardziyenka, M.2
Schumacher, C.A.3
Belterman, C.N.W.4
Van Borren, M.M.5
Verkerk, A.O.6
-
6
-
-
0037401274
-
S R calcium handling and calcium after-transients in a rabbit model of heart failure
-
c
-
Baartscheer A., Schumacher C. A., Belterman C. N. W., Coronel R., Fiolet J. W. T., (2003c). S R calcium handling and calcium after-transients in a rabbit model of heart failure. Heart Fail. 58 99–108. 10.1016/S0008-6363(02)00854-4
-
(2003)
Heart Fail
, vol.58
, pp. 99-108
-
-
Baartscheer, A.1
Schumacher, C.A.2
Belterman, C.N.W.3
Coronel, R.4
Fiolet, J.W.T.5
-
9
-
-
54949109414
-
Sodium ion transporters as new therapeutic targets in heart failure
-
Baartscheer A., Van Borren M. M., (2008). Sodium ion transporters as new therapeutic targets in heart failure. Cardiovasc. Hematol. Agents Med. Chem. 6 229–236. 10.2174/187152508785909546
-
(2008)
Cardiovasc. Hematol. Agents Med. Chem
, vol.6
, pp. 229-236
-
-
Baartscheer, A.1
Van Borren, M.M.2
-
10
-
-
70449729537
-
SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states
-
19509029
-
Banerjee S. K., McGaffin K. R., Pastor-Soler N. M., Ahmad F., (2009). SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states. Cardiovasc. Res. 84 111–118. 10.1093/cvr/cvp190 19509029
-
(2009)
Cardiovasc. Res
, vol.84
, pp. 111-118
-
-
Banerjee, S.K.1
McGaffin, K.R.2
Pastor-Soler, N.M.3
Ahmad, F.4
-
12
-
-
79955442316
-
AMPK activation, a preventive therapeutic target in the transition from cardiac injury to heart failure
-
21285292
-
Beauloye C., Bertrand L., Horman S., Hue L., (2011). AMPK activation, a preventive therapeutic target in the transition from cardiac injury to heart failure. Cardiovasc. Res. 90 224–233. 10.1093/cvr/cvr034 21285292
-
(2011)
Cardiovasc. Res
, vol.90
, pp. 224-233
-
-
Beauloye, C.1
Bertrand, L.2
Horman, S.3
Hue, L.4
-
13
-
-
0037010011
-
Absolute concentrations of high-energy phosphate metabolites in normal, hypertrophied, and failing human myocardium measured noninvasively with 31P-SLOOP magnetic resonance spectroscopy
-
12383574
-
Beer M., Seyfarth T., Sandstede J., Landschütz W., Lipke C., Köstler H., et al. (2002). Absolute concentrations of high-energy phosphate metabolites in normal, hypertrophied, and failing human myocardium measured noninvasively with 31P-SLOOP magnetic resonance spectroscopy. J. Am. Coll. Cardiol. 40 1267–1274. 10.1016/S0735-1097(02)02160-5 12383574
-
(2002)
J. Am. Coll. Cardiol
, vol.40
, pp. 1267-1274
-
-
Beer, M.1
Seyfarth, T.2
Sandstede, J.3
Landschütz, W.4
Lipke, C.5
Köstler, H.6
-
14
-
-
84894146350
-
Cardiac sarcoplasmic reticulum calcium leak: basis and roles in cardiac dysfunction
-
24245942
-
Bers D. M., (2014). Cardiac sarcoplasmic reticulum calcium leak: basis and roles in cardiac dysfunction. Annu. Rev. Physiol. 76 107–127. 10.1146/annurev-physiol-020911-153308 24245942
-
(2014)
Annu. Rev. Physiol
, vol.76
, pp. 107-127
-
-
Bers, D.M.1
-
15
-
-
85049527131
-
Calcium signaling and reactive oxygen species in Mitochondria
-
29748369
-
Bertero E., Maack C., (2018). Calcium signaling and reactive oxygen species in Mitochondria. Circ. Res. 122 1460–1478. 10.1161/CIRCRESAHA.118.310082 29748369
-
(2018)
Circ. Res
, vol.122
, pp. 1460-1478
-
-
Bertero, E.1
Maack, C.2
-
16
-
-
34548848059
-
Mitochondrial energetics in the heart in obesity-related
-
17623815
-
Boudina S., Sena S., Theobald H., Sheng X., Wright J. J., Hu X. X., et al. (2007). Mitochondrial energetics in the heart in obesity-related. Diabetes 56 2457–2466. 10.2337/db07-0481.Additional 17623815
-
(2007)
Diabetes
, vol.56
, pp. 2457-2466
-
-
Boudina, S.1
Sena, S.2
Theobald, H.3
Sheng, X.4
Wright, J.J.5
Hu, X.X.6
-
17
-
-
84896092380
-
Molecular mechanisms of diabetic cardiomyopathy
-
24477973
-
Bugger H., Abel E. D., (2014). Molecular mechanisms of diabetic cardiomyopathy. Diabetologia 57 660–671. 10.1007/s00125-014-3171-6 24477973
-
(2014)
Diabetologia
, vol.57
, pp. 660-671
-
-
Bugger, H.1
Abel, E.D.2
-
18
-
-
85027545481
-
Empagliflozin prevents worsening of cardiac function in an experimental model of pressure overload-induced heart failure
-
30062155
-
Byrne N. J., Parajuli N., Levasseur J. L., Boisvenue J., Beker D. L., Masson G., et al. (2017). Empagliflozin prevents worsening of cardiac function in an experimental model of pressure overload-induced heart failure. JACC Basic Transl. Sci. 2 347–354. 10.1016/j.jacbts.2017.07.003 30062155
-
(2017)
JACC Basic Transl. Sci
, vol.2
, pp. 347-354
-
-
Byrne, N.J.1
Parajuli, N.2
Levasseur, J.L.3
Boisvenue, J.4
Beker, D.L.5
Masson, G.6
-
19
-
-
84924334674
-
Cardiac structure and function are altered in type 2 diabetes and Non-alcoholic fatty liver disease and associate with glycemic control
-
25849783
-
Cassidy S., Hallsworth K., Thoma C., MacGowan G. A., Hollingsworth K. G., Day C. P., et al. (2015). Cardiac structure and function are altered in type 2 diabetes and Non-alcoholic fatty liver disease and associate with glycemic control. Cardiovasc. Diabetol. 14:23. 10.1186/s12933-015-0187-2 25849783
-
(2015)
Cardiovasc. Diabetol
, vol.14
, Issue.23
-
-
Cassidy, S.1
Hallsworth, K.2
Thoma, C.3
MacGowan, G.A.4
Hollingsworth, K.G.5
Day, C.P.6
-
20
-
-
84941340656
-
Impact of diabetes mellitus on hospitalization for heart failure, cardiovascular events, and death: outcomes at 4 years from the reduction of atherothrombosis for continued health (REACH) registry
-
26152709
-
Cavender M. A., Steg P. G., Smith S. C., Eagle K., Ohman E. M., Goto S., et al. (2015). Impact of diabetes mellitus on hospitalization for heart failure, cardiovascular events, and death: outcomes at 4 years from the reduction of atherothrombosis for continued health (REACH) registry. Circulation 132 923–931. 10.1161/CIRCULATIONAHA.114.014796 26152709
-
(2015)
Circulation
, vol.132
, pp. 923-931
-
-
Cavender, M.A.1
Steg, P.G.2
Smith, S.C.3
Eagle, K.4
Ohman, E.M.5
Goto, S.6
-
21
-
-
34447618617
-
Role of endothelin-1, sodium hydrogen exchanger-1 and mitogen activated protein kinase (MAPK) activation in glucose-induced cardiomyocyte hypertrophy
-
17024690
-
Chen S., Khan Z. A., Karmazyn M., Chakrabarti S., (2007). Role of endothelin-1, sodium hydrogen exchanger-1 and mitogen activated protein kinase (MAPK) activation in glucose-induced cardiomyocyte hypertrophy. Diabetes Metab. Res. Rev. 23 356–367. 10.1002/dmrr.689 17024690
-
(2007)
Diabetes Metab. Res. Rev
, vol.23
, pp. 356-367
-
-
Chen, S.1
Khan, Z.A.2
Karmazyn, M.3
Chakrabarti, S.4
-
22
-
-
85035129593
-
AMP-activated protein kinase regulation of the NLRP3 inflammasome during aging
-
29150317
-
Cordero M. D., Williams M. R., Ryffel B., (2018). AMP-activated protein kinase regulation of the NLRP3 inflammasome during aging. Trends Endocrinol. Metab. 29 8–17. 10.1016/j.tem.2017.10.009 29150317
-
(2018)
Trends Endocrinol. Metab
, vol.29
, pp. 8-17
-
-
Cordero, M.D.1
Williams, M.R.2
Ryffel, B.3
-
23
-
-
84887608039
-
Electrophysiological changes in heart failure and their implications for arrhythmogenesis
-
23579069
-
Coronel R., Wilders R., Verkerk A. O., Wiegerinck R. F., Benoist D., Bernus O., (2013). Electrophysiological changes in heart failure and their implications for arrhythmogenesis. Biochim. Biophys. Acta 1832 2432–2441. 10.1016/j.bbadis.2013.04.002 23579069
-
(2013)
Biochim. Biophys. Acta
, vol.1832
, pp. 2432-2441
-
-
Coronel, R.1
Wilders, R.2
Verkerk, A.O.3
Wiegerinck, R.F.4
Benoist, D.5
Bernus, O.6
-
24
-
-
84879360398
-
Diabetes mellitus is associated with adverse prognosis in chronic heart failure of ischaemic and non-ischaemic aetiology
-
23349368
-
Cubbon R. M., Adams B., Rajwani A., Mercer B. N., Patel P. A., Gherardi G., et al. (2013). Diabetes mellitus is associated with adverse prognosis in chronic heart failure of ischaemic and non-ischaemic aetiology. Diabetes Vasc. Dis. Res. 10 330–336. 10.1177/1479164112471064 23349368
-
(2013)
Diabetes Vasc. Dis. Res
, vol.10
, pp. 330-336
-
-
Cubbon, R.M.1
Adams, B.2
Rajwani, A.3
Mercer, B.N.4
Patel, P.A.5
Gherardi, G.6
-
25
-
-
84873561998
-
Amiloride attenuates lipopolysaccharide-accelerated atherosclerosis via inhibition of NHE1-dependent endothelial cell apoptosis
-
23274414
-
Cui G. M., Zhao Y. X., Zhang N. N., Liu Z. S., Sun W. C., Peng Q. S., (2013). Amiloride attenuates lipopolysaccharide-accelerated atherosclerosis via inhibition of NHE1-dependent endothelial cell apoptosis. Acta Pharmacol. Sin. 34 231–238. 10.1038/aps.2012.155 23274414
-
(2013)
Acta Pharmacol. Sin
, vol.34
, pp. 231-238
-
-
Cui, G.M.1
Zhao, Y.X.2
Zhang, N.N.3
Liu, Z.S.4
Sun, W.C.5
Peng, Q.S.6
-
26
-
-
34247885925
-
+ exchanger contributes to left ventricular hypertrophy in the Goto-Kakizaki rat model of type 2 diabetes: critical role of Akt
-
17429605
-
+ exchanger contributes to left ventricular hypertrophy in the Goto-Kakizaki rat model of type 2 diabetes: critical role of Akt. Diabetologia 50 1335–1344. 10.1007/s00125-007-0628-x 17429605
-
(2007)
Diabetologia
, vol.50
, pp. 1335-1344
-
-
Darmellah, A.1
Baetz, D.2
Prunier, F.3
Tamareille, S.4
Rücker-Martin, C.5
Feuvray, D.6
-
27
-
-
85055134565
-
+]I dysregulation in heart failure and diabetic cardiomyopathy
-
+]I dysregulation in heart failure and diabetic cardiomyopathy. Front. Physiol. 9:1303. 10.3389/fphys.2018.01303
-
(2018)
Front. Physiol
, vol.9
, Issue.1303
-
-
Despa, S.1
-
30
-
-
85054970157
-
Mitochondrial ROS drive sudden cardiac death and chronic proteome remodeling in heart failurenovelty and significance
-
29898892
-
Dey S., DeMazumder D., Sidor A., Foster D. B., O’Rourke B., (2018). Mitochondrial ROS drive sudden cardiac death and chronic proteome remodeling in heart failurenovelty and significance. Circ. Res. 123 356–371. 10.1161/CIRCRESAHA.118.312708 29898892
-
(2018)
Circ. Res
, vol.123
, pp. 356-371
-
-
Dey, S.1
DeMazumder, D.2
Sidor, A.3
Foster, D.B.4
O’Rourke, B.5
-
31
-
-
85020133383
-
Sodium-dependent glucose transporters (SGLT) in human ischemic heart: a new potential pharmacological target
-
28526540
-
Di Franco A., Cantini G., Tani A., Coppini R., Zecchi-Orlandini S., Raimondi L., et al. (2017). Sodium-dependent glucose transporters (SGLT) in human ischemic heart: a new potential pharmacological target. Int. J. Cardiol. 243 86–90. 10.1016/j.ijcard.2017.05.032 28526540
-
(2017)
Int. J. Cardiol
, vol.243
, pp. 86-90
-
-
Di Franco, A.1
Cantini, G.2
Tani, A.3
Coppini, R.4
Zecchi-Orlandini, S.5
Raimondi, L.6
-
32
-
-
84934957566
-
Elevated sodium and dehydration stimulate inflammatory signaling in endothelial cells and promote atherosclerosis
-
26042828
-
Dmitrieva N. I., Burg M. B., (2015). Elevated sodium and dehydration stimulate inflammatory signaling in endothelial cells and promote atherosclerosis. PLoS One 10:e0128870. 10.1371/journal.pone.0128870 26042828
-
(2015)
PLoS One
, vol.10
, Issue.e0128870
-
-
Dmitrieva, N.I.1
Burg, M.B.2
-
33
-
-
84938212697
-
Effect of metformin pretreatment on myocardial injury during coronary artery bypass surgery in patients without diabetes (MetCAB): a double-blind, randomised controlled trial
-
26179504
-
El Messaoudi S., Nederlof R., Zuurbier C. J., van Swieten H. A., Pickkers P., Noyez L., et al. (2015). Effect of metformin pretreatment on myocardial injury during coronary artery bypass surgery in patients without diabetes (MetCAB): a double-blind, randomised controlled trial. Lancet Diabetes Endocrinol. 3 615–623. 10.1016/S2213-8587(15)00121-7 26179504
-
(2015)
Lancet Diabetes Endocrinol
, vol.3
, pp. 615-623
-
-
El Messaoudi, S.1
Nederlof, R.2
Zuurbier, C.J.3
van Swieten, H.A.4
Pickkers, P.5
Noyez, L.6
-
34
-
-
85048895435
-
Hyperglycaemic impairment of PAR2-mediated vasodilation: prevention by inhibition of aortic endothelial sodium-glucose-co- Transporter-2 and minimizing oxidative stress
-
29908295
-
El-daly M., Krishna V., Venu P., Mihara K., Kang S., Fedak P. W. M., et al. (2018). Hyperglycaemic impairment of PAR2-mediated vasodilation: prevention by inhibition of aortic endothelial sodium-glucose-co- Transporter-2 and minimizing oxidative stress. Vascul. Pharmacol. 109 56–71. 10.1016/j.vph.2018.06.006 29908295
-
(2018)
Vascul. Pharmacol
, vol.109
, pp. 56-71
-
-
El-daly, M.1
Krishna, V.2
Venu, P.3
Mihara, K.4
Kang, S.5
Fedak, P.W.M.6
-
35
-
-
0037134401
-
+ exchange prevents hypertrophy, fibrosis, and heart failure in beta1-adrenergic receptor transgenic mice
-
+ exchange prevents hypertrophy, fibrosis, and heart failure in beta1-adrenergic receptor transgenic mice. Circ. Res. 90 814–819. 10.1161/01.RES.0000014966.97486.C0
-
(2002)
Circ. Res
, vol.90
, pp. 814-819
-
-
Engelhardt, S.1
-
36
-
-
84885863770
-
Diabetic hyperglycemia activates CaMKII and arrhythmias by O linked glycosylation
-
24077098
-
Erickson J. R., Pereira L., Wang L., Han G., Ferguson A., Dao K., et al. (2013). Diabetic hyperglycemia activates CaMKII and arrhythmias by O linked glycosylation. Nature 502 372–376. 10.1038/nature12537.Diabetic 24077098
-
(2013)
Nature
, vol.502
, pp. 372-376
-
-
Erickson, J.R.1
Pereira, L.2
Wang, L.3
Han, G.4
Ferguson, A.5
Dao, K.6
-
37
-
-
0036227620
-
Salt intake and hypertension therapy
-
Feldstein C. A., (2002). Salt intake and hypertension therapy. J. Hum. Hypertens. 16 48–51. 10.1038/sj/jhh/1001342
-
(2002)
J. Hum. Hypertens
, vol.16
, pp. 48-51
-
-
Feldstein, C.A.1
-
38
-
-
84951906012
-
Energy balance after sodium–glucose cotransporter 2 inhibition
-
26180105
-
Ferrannini G., Hach T., Crowe S., Sanghvi A., Hall K. D., Ferrannini E., (2015). Energy balance after sodium–glucose cotransporter 2 inhibition. Diabetes Care 38 1730–1735. 10.2337/dc15-0355 26180105
-
(2015)
Diabetes Care
, vol.38
, pp. 1730-1735
-
-
Ferrannini, G.1
Hach, T.2
Crowe, S.3
Sanghvi, A.4
Hall, K.D.5
Ferrannini, E.6
-
39
-
-
84919615360
-
Metformin: from mechanisms of action to therapies
-
25456737
-
Foretz M., Guigas B., Berbrand L., Pollak M., Viollet B., (2014). Metformin: from mechanisms of action to therapies. Cell Metab. 20 953–966. 10.1016/j.cmet.2014.09.018 25456737
-
(2014)
Cell Metab
, vol.20
, pp. 953-966
-
-
Foretz, M.1
Guigas, B.2
Berbrand, L.3
Pollak, M.4
Viollet, B.5
-
40
-
-
85019634930
-
An overview of the inflammatory signalling mechanisms in themyocardiumunderlying the development of diabetic cardiomyopathy
-
28395009
-
Frati G., Schirone L., Chimenti I., Yee D., Biondi-Zoccai G., Volpe M., et al. (2017). An overview of the inflammatory signalling mechanisms in themyocardiumunderlying the development of diabetic cardiomyopathy. Cardiovasc. Res. 113 378–388. 10.1093/cvr/cvx011 28395009
-
(2017)
Cardiovasc. Res
, vol.113
, pp. 378-388
-
-
Frati, G.1
Schirone, L.2
Chimenti, I.3
Yee, D.4
Biondi-Zoccai, G.5
Volpe, M.6
-
41
-
-
84860200741
-
Calcium-mediated cell death during myocardial reperfusion
-
22499772
-
Garcia-Dorado D., Ruiz-Meana M., Inserte J., Rodriguez-Sinovas A., Piper H. M., (2012). Calcium-mediated cell death during myocardial reperfusion. Cardiovasc. Res. 94 168–180. 10.1093/cvr/cvs116 22499772
-
(2012)
Cardiovasc. Res
, vol.94
, pp. 168-180
-
-
Garcia-Dorado, D.1
Ruiz-Meana, M.2
Inserte, J.3
Rodriguez-Sinovas, A.4
Piper, H.M.5
-
42
-
-
85038601912
-
Dapagliflozin attenuates human vascular endothelial cell activation and induces vasorelaxation: a potential mechanism for inhibition of atherogenesis
-
29923421
-
Gaspari T., Spizzo I., Liu H., Hu Y., Simpson R. W., Widdop R. E., et al. (2017). Dapagliflozin attenuates human vascular endothelial cell activation and induces vasorelaxation: a potential mechanism for inhibition of atherogenesis. Diabetes Vasc. Dis. Res. 15 64–73. 10.1177/1479164117733626 29923421
-
(2017)
Diabetes Vasc. Dis. Res
, vol.15
, pp. 64-73
-
-
Gaspari, T.1
Spizzo, I.2
Liu, H.3
Hu, Y.4
Simpson, R.W.5
Widdop, R.E.6
-
43
-
-
85041048743
-
AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation
-
29371602
-
Gélinas R., Mailleux F., Dontaine J., Bultot L., Demeulder B., Ginion A., et al. (2018). AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation. Nat. Commun. 9:374. 10.1038/s41467-017-02795-4 29371602
-
(2018)
Nat. Commun
, vol.9
, Issue.374
-
-
Gélinas, R.1
Mailleux, F.2
Dontaine, J.3
Bultot, L.4
Demeulder, B.5
Ginion, A.6
-
44
-
-
84859560882
-
+ in the regulation of cellular energetics
-
22443365
-
+ in the regulation of cellular energetics. Biochemistry 51 2959–2973. 10.1021/bi2018909 22443365
-
(2012)
Biochemistry
, vol.51
, pp. 2959-2973
-
-
Glancy, B.1
Balaban, R.S.2
-
46
-
-
84946434020
-
SGLT inhibitors attenuate NO-dependent vascular relaxation in the pulmonary artery but not in the coronary artery
-
26361875
-
Han Y., Cho Y.-E., Ayon R., Guo R., Youssef K. D., Pan M., et al. (2015). SGLT inhibitors attenuate NO-dependent vascular relaxation in the pulmonary artery but not in the coronary artery. Am. J. Physiol. Lung Cell. Mol. Physiol. 309 L1027–L1036. 10.1152/ajplung.00167.2015 26361875
-
(2015)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.309
, pp. L1027-L1036
-
-
Han, Y.1
Cho, Y.-E.2
Ayon, R.3
Guo, R.4
Youssef, K.D.5
Pan, M.6
-
47
-
-
84987624200
-
+/glucose cotransporter inhibitor canagliflozin activates AMPK by inhibiting mitochondrial function and increasing cellular AMP levels
-
27381369
-
+/glucose cotransporter inhibitor canagliflozin activates AMPK by inhibiting mitochondrial function and increasing cellular AMP levels. Diabetes Metab. Res. Rev. 65 2784–2794. 10.2337/db16-0058 27381369
-
(2016)
Diabetes Metab. Res. Rev
, vol.65
, pp. 2784-2794
-
-
Hawley, S.A.1
Ford, R.J.2
Smith, B.K.3
Gowans, G.J.4
Mancini, S.J.5
Pitt, R.D.6
-
48
-
-
84962157108
-
AMPK suppresses vascular inflammation in vivo by inhibiting signal transducer and activator of transcription-1
-
25858560
-
He C., Li H., Viollet B., Zou M. H., Xie Z., (2015). AMPK suppresses vascular inflammation in vivo by inhibiting signal transducer and activator of transcription-1. Diabetes Metab. Res. Rev. 64 4285–4297. 10.2337/db15-0107 25858560
-
(2015)
Diabetes Metab. Res. Rev
, vol.64
, pp. 4285-4297
-
-
He, C.1
Li, H.2
Viollet, B.3
Zou, M.H.4
Xie, Z.5
-
49
-
-
85046091468
-
Role of salt intake in prevention of cardiovascular disease: controversies and challenges
-
29713009
-
He F. J., MacGregor G. A., (2018). Role of salt intake in prevention of cardiovascular disease: controversies and challenges. Nat. Rev. Cardiol. 15 371–377. 10.1038/s41569-018-0004-1 29713009
-
(2018)
Nat. Rev. Cardiol
, vol.15
, pp. 371-377
-
-
He, F.J.1
MacGregor, G.A.2
-
50
-
-
59449085388
-
Energy metabolism in heart failure and remodelling
-
18987051
-
Ingwall J. S., (2009). Energy metabolism in heart failure and remodelling. Cardiovasc. Res. 81 412–419. 10.1093/cvr/cvn301 18987051
-
(2009)
Cardiovasc. Res
, vol.81
, pp. 412-419
-
-
Ingwall, J.S.1
-
51
-
-
0035043777
-
Arrhythmogenesis in heart failure
-
Janse M. J., Vermeulen J. T., Opthof T., Coronel R., Wilms-Schopman F. J., Rademaker H. M. E., et al. (2001). Arrhythmogenesis in heart failure. J. Cardiovasc. Electrophysiol. 12 496–499. 10.1046/j.1540-8167.2001.00496.x
-
(2001)
J. Cardiovasc. Electrophysiol
, vol.12
, pp. 496-499
-
-
Janse, M.J.1
Vermeulen, J.T.2
Opthof, T.3
Coronel, R.4
Wilms-Schopman, F.J.5
Rademaker, H.M.E.6
-
52
-
-
85048712205
-
Sodium glucose transporter 2 (SGLT2) inhibition does not protect the myocardium from acute ischemic reperfusion injury but modulates post- ischemic mitochondrial function
-
Jespersen N. R., Lassen T. R., Hjortbak M. V., Stottrup N. B., Botker H. E., (2017). Sodium glucose transporter 2 (SGLT2) inhibition does not protect the myocardium from acute ischemic reperfusion injury but modulates post- ischemic mitochondrial function. Cardiovasc. Pharmacol. Open Access. 6 2–4. 10.4172/2329-6607.1000210
-
(2017)
Cardiovasc. Pharmacol. Open Access
, vol.6
, pp. 2-4
-
-
Jespersen, N.R.1
Lassen, T.R.2
Hjortbak, M.V.3
Stottrup, N.B.4
Botker, H.E.5
-
53
-
-
85044730815
-
Diabetic cardiomyopathy: an update of mechanisms contributing to this clinical entity
-
29449364
-
Jia G., Hill M. A., Sowers J. R., (2018). Diabetic cardiomyopathy: an update of mechanisms contributing to this clinical entity. Circ. Res. 122 624–638. 10.1161/CIRCRESAHA.117.311586 29449364
-
(2018)
Circ. Res
, vol.122
, pp. 624-638
-
-
Jia, G.1
Hill, M.A.2
Sowers, J.R.3
-
54
-
-
84891555789
-
Conundrum of pathogenesis of diabetic cardiomyopathy: role of vascular endothelial dysfunction, reactive oxygen species, and mitochondria
-
24307101
-
Joshi M., Kotha S. R., Malireddy S., Selvaraju V., Satoskar A. R., Palesty A., et al. (2014). Conundrum of pathogenesis of diabetic cardiomyopathy: role of vascular endothelial dysfunction, reactive oxygen species, and mitochondria. Mol. Cell. Biochem. 386 233–249. 10.1007/s11010-013-1861-x 24307101
-
(2014)
Mol. Cell. Biochem
, vol.386
, pp. 233-249
-
-
Joshi, M.1
Kotha, S.R.2
Malireddy, S.3
Selvaraju, V.4
Satoskar, A.R.5
Palesty, A.6
-
55
-
-
0016251063
-
Role of diabetes in congestive heart failure: the Framingham study
-
Kannel W. B., Hjortland M., Castelli W. P., (1974). Role of diabetes in congestive heart failure: the Framingham study. Am. J. Cardiol. 34 29–34. 10.1016/0002-9149(74)90089-7
-
(1974)
Am. J. Cardiol
, vol.34
, pp. 29-34
-
-
Kannel, W.B.1
Hjortland, M.2
Castelli, W.P.3
-
56
-
-
84880332023
-
NHE-1: still a viable therapeutic target
-
23429008
-
Karmazyn M., (2013). NHE-1: still a viable therapeutic target. J. Mol. Cell. Cardiol. 61 77–82. 10.1016/j.yjmcc.2013.02.006 23429008
-
(2013)
J. Mol. Cell. Cardiol
, vol.61
, pp. 77-82
-
-
Karmazyn, M.1
-
57
-
-
84938710060
-
Expression of SGLT1 in human hearts and impairment of cardiac glucose uptake by phlorizin during ischemia-reperfusion injury in mice
-
26121582
-
Kashiwagi Y., Nagoshi T., Yoshino T., Tanaka T. D., Ito K., Harada T., et al. (2015). Expression of SGLT1 in human hearts and impairment of cardiac glucose uptake by phlorizin during ischemia-reperfusion injury in mice. PLoS One 10:e0130605. 10.1371/journal.pone.0130605 26121582
-
(2015)
PLoS One
, vol.10
, Issue.e0130605
-
-
Kashiwagi, Y.1
Nagoshi, T.2
Yoshino, T.3
Tanaka, T.D.4
Ito, K.5
Harada, T.6
-
58
-
-
79959423575
-
Effect of a high-fat meal on the pharmacokinetics of dapagliflozin, a selective SGLT2 inhibitor, in healthy subjects
-
21435141
-
Kasichayanula S., Liu X., Zhang W., Pfister M., Reele S. B., Aubry A. F., et al. (2011). Effect of a high-fat meal on the pharmacokinetics of dapagliflozin, a selective SGLT2 inhibitor, in healthy subjects. Diabetes Obes. Metab. 13 770–773. 10.1111/j.1463-1326.2011.01397.x 21435141
-
(2011)
Diabetes Obes. Metab
, vol.13
, pp. 770-773
-
-
Kasichayanula, S.1
Liu, X.2
Zhang, W.3
Pfister, M.4
Reele, S.B.5
Aubry, A.F.6
-
59
-
-
0034996073
-
+ exchange inhibition reduces hypertrophy and heart failure after myocardial infarction in rats
-
11158973
-
+ exchange inhibition reduces hypertrophy and heart failure after myocardial infarction in rats. Am. J. Physiol. Hear. Circ. Physiol. 280 H738–H745. 10.1152/ajpheart.2001.280.2.H738 11158973
-
(2001)
Am. J. Physiol. Hear. Circ. Physiol
, vol.280
, pp. H738-H745
-
-
Kusumoto, K.1
Haist, J.V.2
Karmazyn, M.3
-
61
-
-
85044254123
-
High salt intake causes leptin resistance and obesity in mice by stimulating endogenous fructose production and metabolism
-
29507217
-
Lanaspa M. A., Kuwabara M., Andres-Hernando A., Li N., Cicerchi C., Jensen T., et al. (2018). High salt intake causes leptin resistance and obesity in mice by stimulating endogenous fructose production and metabolism. Proc. Natl. Acad. Sci. U.S.A. 115:201713837. 10.1073/pnas.1713837115 29507217
-
(2018)
Proc. Natl. Acad. Sci. U.S.A
, vol.115
-
-
Lanaspa, M.A.1
Kuwabara, M.2
Andres-Hernando, A.3
Li, N.4
Cicerchi, C.5
Jensen, T.6
-
62
-
-
77957311044
-
Salt, aldosterone, and insulin resistance: impact on the cardiovascular system
-
20697411
-
Lastra G., Dhuper S., Johnson M. S., Sowers J. R., (2010). Salt, aldosterone, and insulin resistance: impact on the cardiovascular system. Nat. Rev. Cardiol. 7 577–584. 10.1038/nrcardio.2010.123 20697411
-
(2010)
Nat. Rev. Cardiol
, vol.7
, pp. 577-584
-
-
Lastra, G.1
Dhuper, S.2
Johnson, M.S.3
Sowers, J.R.4
-
63
-
-
85010842028
-
Dapagliflozin, a selective SGLT2 Inhibitor, attenuated cardiac fibrosis by regulating the macrophage polarization via STAT3 signaling in infarcted rat hearts
-
28132924
-
Lee T. M., Chang N. C., Lin S. Z., (2017). Dapagliflozin, a selective SGLT2 Inhibitor, attenuated cardiac fibrosis by regulating the macrophage polarization via STAT3 signaling in infarcted rat hearts. Free Radic. Biol. Med. 104 298–310. 10.1016/j.freeradbiomed.2017.01.035 28132924
-
(2017)
Free Radic. Biol. Med
, vol.104
, pp. 298-310
-
-
Lee, T.M.1
Chang, N.C.2
Lin, S.Z.3
-
64
-
-
85015953289
-
Cardiac energetics, oxygenation, and perfusion during increased workload in patients with type 2 diabetes mellitus
-
26392437
-
Levelt E., Rodgers C. T., Clarke W. T., Mahmod M., Ariga R., Francis J. M., et al. (2016). Cardiac energetics, oxygenation, and perfusion during increased workload in patients with type 2 diabetes mellitus. Eur. Heart J. 37 3461–3469. 10.1093/eurheartj/ehv442 26392437
-
(2016)
Eur. Heart J
, vol.37
, pp. 3461-3469
-
-
Levelt, E.1
Rodgers, C.T.2
Clarke, W.T.3
Mahmod, M.4
Ariga, R.5
Francis, J.M.6
-
65
-
-
85045770225
-
Phlorizin exerts direct protective effects on palmitic acid (PA)-induced endothelial dysfunction by activating the PI3K/AKT/eNOS signaling pathway and increasing the levels of nitric oxide (NO)
-
29307883
-
Li C.-Y., Wang L.-X., Dong S.-S., Hong Y., Zhou X.-H., Zheng W.-W., et al. (2018). Phlorizin exerts direct protective effects on palmitic acid (PA)-induced endothelial dysfunction by activating the PI3K/AKT/eNOS signaling pathway and increasing the levels of nitric oxide (NO). Med. Sci. Monit. Basic Res. 24 1–9. 10.12659/MSMBR.907775 29307883
-
(2018)
Med. Sci. Monit. Basic Res
, vol.24
, pp. 1-9
-
-
Li, C.-Y.1
Wang, L.-X.2
Dong, S.-S.3
Hong, Y.4
Zhou, X.-H.5
Zheng, W.-W.6
-
66
-
-
84955242874
-
Pharmacological activation of AMPK prevents Drp1-mediated mitochondrial fission and alleviates endoplasmic reticulum stress-associated endothelial dysfunction
-
26196303
-
Li J., Wang Y., Wang Y., Wen X., Ma X. N., Chen W., et al. (2015). Pharmacological activation of AMPK prevents Drp1-mediated mitochondrial fission and alleviates endoplasmic reticulum stress-associated endothelial dysfunction. J. Mol. Cell. Cardiol. 86 62–74. 10.1016/j.yjmcc.2015.07.010 26196303
-
(2015)
J. Mol. Cell. Cardiol
, vol.86
, pp. 62-74
-
-
Li, J.1
Wang, Y.2
Wang, Y.3
Wen, X.4
Ma, X.N.5
Chen, W.6
-
67
-
-
53549099939
-
+ uptake in myocytes from failing hearts restores energy supply and demand matching
-
18599868
-
+ uptake in myocytes from failing hearts restores energy supply and demand matching. Circ. Res. 103 279–288. 10.1161/CIRCRESAHA.108.175919 18599868
-
(2008)
Circ. Res
, vol.103
, pp. 279-288
-
-
Liu, T.1
Rourke, B.O.2
-
68
-
-
84874607556
-
Diabetes increases mortality after myocardial infarction by oxidizing CaMKII
-
23426181
-
Luo M., Guan X., Luczak E. D., Lang D., Kutschke W., Gao Z., et al. (2013). Diabetes increases mortality after myocardial infarction by oxidizing CaMKII. J. Clin. Invest. 123 1262–1274. 10.1172/JCI65268 23426181
-
(2013)
J. Clin. Invest
, vol.123
, pp. 1262-1274
-
-
Luo, M.1
Guan, X.2
Luczak, E.D.3
Lang, D.4
Kutschke, W.5
Gao, Z.6
-
69
-
-
85044585390
-
Canagliflozin inhibits interleukin-1β-stimulated cytokine and chemokine secretion in vascular endothelial cells by AMP-activated protein kinase-dependent and -independent mechanisms
-
29588466
-
Mancini S. J., Boyd D., Katwan O. J., Strembitska A., Almabrouk T. A., Kennedy S., et al. (2018). Canagliflozin inhibits interleukin-1β-stimulated cytokine and chemokine secretion in vascular endothelial cells by AMP-activated protein kinase-dependent and -independent mechanisms. Sci. Rep. 8:5276. 10.1038/s41598-018-23420-4 29588466
-
(2018)
Sci. Rep
, vol.8
, Issue.5276
-
-
Mancini, S.J.1
Boyd, D.2
Katwan, O.J.3
Strembitska, A.4
Almabrouk, T.A.5
Kennedy, S.6
-
70
-
-
40749126460
-
Sodium-hydrogen exchange inhibition by cariporide to reduce the risk of ischemic cardiac events in patients undergoing coronary artery bypass grafting: results of the EXPEDITION study
-
18355507
-
Mentzer R. M., Bartels C., Bolli R., Boyce S., Buckberg G. D., Chaitman B., et al. (2008). Sodium-hydrogen exchange inhibition by cariporide to reduce the risk of ischemic cardiac events in patients undergoing coronary artery bypass grafting: results of the EXPEDITION study. Ann. Thorac. Surg. 85 1261–1270. 10.1016/j.athoracsur.2007.10.054 18355507
-
(2008)
Ann. Thorac. Surg
, vol.85
, pp. 1261-1270
-
-
Mentzer, R.M.1
Bartels, C.2
Bolli, R.3
Boyce, S.4
Buckberg, G.D.5
Chaitman, B.6
-
71
-
-
84876569165
-
Diabetic cardiomyopathy: pathophysiology and clinical features
-
22453289
-
Miki T., Yuda S., Kouzu H., Miura T., (2013). Diabetic cardiomyopathy: pathophysiology and clinical features. Heart Fail. Rev. 18 149–166. 10.1007/s10741-012-9313-3 22453289
-
(2013)
Heart Fail. Rev
, vol.18
, pp. 149-166
-
-
Miki, T.1
Yuda, S.2
Kouzu, H.3
Miura, T.4
-
72
-
-
84942252892
-
Type-2 diabetes increases autophagy in the human heart through promotion of Beclin-1 mediated pathway
-
26386349
-
Munasinghe P. E., Riu F., Dixit P., Edamatsu M., Saxena P., Hamer N. S. J., et al. (2016). Type-2 diabetes increases autophagy in the human heart through promotion of Beclin-1 mediated pathway. Int. J. Cardiol. 202 13–20. 10.1016/j.ijcard.2015.08.111 26386349
-
(2016)
Int. J. Cardiol
, vol.202
, pp. 13-20
-
-
Munasinghe, P.E.1
Riu, F.2
Dixit, P.3
Edamatsu, M.4
Saxena, P.5
Hamer, N.S.J.6
-
74
-
-
84941199001
-
Pathophysiological role of oxidative stress in systolic and diastolic heart failure and its therapeutic implications
-
26142467
-
Münzel T., Gori T., Keaney J. F., Maack C., Daiber A., (2015). Pathophysiological role of oxidative stress in systolic and diastolic heart failure and its therapeutic implications. Eur. Heart J. 36 2555–2564. 10.1093/eurheartj/ehv305 26142467
-
(2015)
Eur. Heart J
, vol.36
, pp. 2555-2564
-
-
Münzel, T.1
Gori, T.2
Keaney, J.F.3
Maack, C.4
Daiber, A.5
-
75
-
-
61949206575
-
Regulation of intracellular and mitochondrial sodium in health and disease
-
19213964
-
Murphy E., Eisner D. A., (2009). Regulation of intracellular and mitochondrial sodium in health and disease. Circ. Res. 104 292–303. 10.1161/CIRCRESAHA.108.189050 19213964
-
(2009)
Circ. Res
, vol.104
, pp. 292-303
-
-
Murphy, E.1
Eisner, D.A.2
-
76
-
-
85056353256
-
Empagliflozin reduces Ca/calmodulin-dependent kinase II activity in isolated ventricular cardiomyocytes
-
30117720
-
Mustroph J., Wagemann O., Lücht C. M., Trum M., Hammer K. P., Martin C., et al. (2018). Empagliflozin reduces Ca/calmodulin-dependent kinase II activity in isolated ventricular cardiomyocytes. ESC Hear. Fail. 5 642–648. 10.1002/ehf2.12336 30117720
-
(2018)
ESC Hear. Fail
, vol.5
, pp. 642-648
-
-
Mustroph, J.1
Wagemann, O.2
Lücht, C.M.3
Trum, M.4
Hammer, K.P.5
Martin, C.6
-
77
-
-
85023777061
-
Canagliflozin and cardiovascular and renal events in type 2 diabetes
-
28605608
-
Neal B., Perkovic V., Mahaffey K. W., de Zeeuw D., Fulcher G., Erondu N., et al. (2017). Canagliflozin and cardiovascular and renal events in type 2 diabetes. N. Engl. J. Med. 377 644–657. 10.1056/NEJMoa1611925 28605608
-
(2017)
N. Engl. J. Med
, vol.377
, pp. 644-657
-
-
Neal, B.1
Perkovic, V.2
Mahaffey, K.W.3
de Zeeuw, D.4
Fulcher, G.5
Erondu, N.6
-
79
-
-
33947239659
-
The failing heart — an engine out of fuel
-
17360992
-
Neubauer S., (2007). The failing heart — an engine out of fuel. N. Engl. J. Med. 356 1140–1151. 10.1056/NEJMra063052 17360992
-
(2007)
N. Engl. J. Med
, vol.356
, pp. 1140-1151
-
-
Neubauer, S.1
-
80
-
-
84911942671
-
The sodium-glucose co-transporter 2 inhibitor empagliflozin improves diabetes-induced vascular dysfunction in the streptozotocin diabetes rat model by interfering with oxidative stress and glucotoxicity
-
25402275
-
Oelze M., Kröller-Schön S., Welschof P., Jansen T., Hausding M., Mikhed Y., et al. (2014). The sodium-glucose co-transporter 2 inhibitor empagliflozin improves diabetes-induced vascular dysfunction in the streptozotocin diabetes rat model by interfering with oxidative stress and glucotoxicity. PLoS One 9:e112394. 10.1371/journal.pone.0112394 25402275
-
(2014)
PLoS One
, vol.9
, Issue.e112394
-
-
Oelze, M.1
Kröller-Schön, S.2
Welschof, P.3
Jansen, T.4
Hausding, M.5
Mikhed, Y.6
-
81
-
-
85031915334
-
Activation and inhibition of sodium-hydrogen exchanger is a mechanism that links the pathophysiology and treatment of diabetes mellitus with that of heart failure
-
29038209
-
Packer M., (2017). Activation and inhibition of sodium-hydrogen exchanger is a mechanism that links the pathophysiology and treatment of diabetes mellitus with that of heart failure. Circulation 136 1548–1559. 10.1161/CIRCULATIONAHA.117.030418 29038209
-
(2017)
Circulation
, vol.136
, pp. 1548-1559
-
-
Packer, M.1
-
82
-
-
84879748718
-
A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation
-
23684677
-
Paulus W. J., Tschöpe C., (2013). A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation. J. Am. Coll. Cardiol. 62 263–271. 10.1016/j.jacc.2013.02.092 23684677
-
(2013)
J. Am. Coll. Cardiol
, vol.62
, pp. 263-271
-
-
Paulus, W.J.1
Tschöpe, C.2
-
83
-
-
0037377081
-
Intracellular Na in animal models of hypertrophy and heart failure: contractile function and arrhythmogenesis
-
12650867
-
Pogwizd S. M., Sipido K. R., Verdonck F., Bers D. M., (2003). Intracellular Na in animal models of hypertrophy and heart failure: contractile function and arrhythmogenesis. Cardiovasc. Res. 57 887–896. 10.1016/S0008-6363(02)00735-6 12650867
-
(2003)
Cardiovasc. Res
, vol.57
, pp. 887-896
-
-
Pogwizd, S.M.1
Sipido, K.R.2
Verdonck, F.3
Bers, D.M.4
-
84
-
-
85007297398
-
Insulin signaling and heart failure
-
27034277
-
Riehle C., Abel E., (2016). Insulin signaling and heart failure. Circ. Res. 118 1151–1169. 10.1161/CIRCRESAHA.116.306206 27034277
-
(2016)
Circ. Res
, vol.118
, pp. 1151-1169
-
-
Riehle, C.1
Abel, E.2
-
86
-
-
84898434447
-
Evaluating SGLT2 inhibitors for type 2 diabetes: pharmacokinetic and toxicological considerations
-
24387329
-
Scheen A. J., (2014). Evaluating SGLT2 inhibitors for type 2 diabetes: pharmacokinetic and toxicological considerations. Expert Opin. Drug Metab. Toxicol. 10 647–663. 10.1517/17425255.2014.873788 24387329
-
(2014)
Expert Opin. Drug Metab. Toxicol
, vol.10
, pp. 647-663
-
-
Scheen, A.J.1
-
87
-
-
84884324699
-
Endothelial dysfunction - A major mediator of diabetic vascular disease
-
23994612
-
Sena C. M., Pereira A. M., Seiça R., (2013). Endothelial dysfunction - A major mediator of diabetic vascular disease. Biochim. Biophys. Acta 1832 2216–2231. 10.1016/j.bbadis.2013.08.006 23994612
-
(2013)
Biochim. Biophys. Acta
, vol.1832
, pp. 2216-2231
-
-
Sena, C.M.1
Pereira, A.M.2
Seiça, R.3
-
88
-
-
84971265146
-
Molecular and cellular mechanisms of cardiovascular disorders in diabetes
-
Shah M. S., Brownlee M., (2017). Molecular and cellular mechanisms of cardiovascular disorders in diabetes. Circ. Res. 118 1808–1829. 10.1161/CIRCRESAHA.116.306923.Molecular
-
(2017)
Circ. Res
, vol.118
, pp. 1808-1829
-
-
Shah, M.S.1
Brownlee, M.2
-
89
-
-
85042221426
-
Oxidative stress and NLRP3-inflammasome activity as significant drivers of diabetic cardiovascular complications: therapeutic implications
-
29515457
-
Sharma A., Tate M., Mathew G., Vince J. E., Ritchie R. H., De Haan J. B., (2018). Oxidative stress and NLRP3-inflammasome activity as significant drivers of diabetic cardiovascular complications: therapeutic implications. Front. Physiol. 9:114. 10.3389/fphys.2018.00114 29515457
-
(2018)
Front. Physiol
, vol.9
, Issue.114
-
-
Sharma, A.1
Tate, M.2
Mathew, G.3
Vince, J.E.4
Ritchie, R.H.5
De Haan, J.B.6
-
90
-
-
85021409196
-
The SGLT2 inhibitor empagliflozin improves the primary diabetic complications in ZDF rats
-
28667906
-
Steven S., Oelze M., Hanf A., Kröller-Schön S., Kashani F., Roohani S., et al. (2017). The SGLT2 inhibitor empagliflozin improves the primary diabetic complications in ZDF rats. Redox Biol. 13 370–385. 10.1016/j.redox.2017.06.009 28667906
-
(2017)
Redox Biol
, vol.13
, pp. 370-385
-
-
Steven, S.1
Oelze, M.2
Hanf, A.3
Kröller-Schön, S.4
Kashani, F.5
Roohani, S.6
-
91
-
-
84861536065
-
Tofogliflozin, a potent and highly specific sodium/glucose cotransporter 2 inhibitor, improves glycemic control in diabetic rats and mice
-
22410641
-
Suzuki M., Honda K., Fukazawa M., Ozawa K., Hagita H., Kawai T., et al. (2012). Tofogliflozin, a potent and highly specific sodium/glucose cotransporter 2 inhibitor, improves glycemic control in diabetic rats and mice. J. Pharmacol. Exp. Ther. 341 692–701. 10.1124/jpet.112.191593 22410641
-
(2012)
J. Pharmacol. Exp. Ther
, vol.341
, pp. 692-701
-
-
Suzuki, M.1
Honda, K.2
Fukazawa, M.3
Ozawa, K.4
Hagita, H.5
Kawai, T.6
-
92
-
-
85042119123
-
Cardioprotection of dapagliflozin and vildagliptin in rats with cardiac ischemia-reperfusion injury
-
29142025
-
Tanajak P., Sa-nguanmoo P., Sivasinprasasn S., Thummasorn S., Siri-Angkul N., Chattipakorn S. C., et al. (2018). Cardioprotection of dapagliflozin and vildagliptin in rats with cardiac ischemia-reperfusion injury. J. Endocrinol. 236 69–84. 10.1530/JOE-17-0457 29142025
-
(2018)
J. Endocrinol
, vol.236
, pp. 69-84
-
-
Tanajak, P.1
Sa-nguanmoo, P.2
Sivasinprasasn, S.3
Thummasorn, S.4
Siri-Angkul, N.5
Chattipakorn, S.C.6
-
94
-
-
0034687597
-
Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations. main results of the GUARDIAN trial
-
11120691
-
Théroux P., Chaitman B. R., Danchin N., Erhardt L., Meinertz T., Schroeder J. S., et al. (2000). Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations. main results of the GUARDIAN trial. Circulation 102 3032–3038. 10.1161/01.CIR.102.25.3032 11120691
-
(2000)
Circulation
, vol.102
, pp. 3032-3038
-
-
Théroux, P.1
Chaitman, B.R.2
Danchin, N.3
Erhardt, L.4
Meinertz, T.5
Schroeder, J.S.6
-
95
-
-
0035797839
-
Increased adenosine monophosphate-activated protein kinase activity in rat hearts with pressure-overload hypertrophy
-
11581146
-
Tian R., Musi N., D’Agostino J., Hirshman M. F., Goodyear L. J., (2001). Increased adenosine monophosphate-activated protein kinase activity in rat hearts with pressure-overload hypertrophy. Circulation 104 1664–1669. 10.1161/hc4001.097183 11581146
-
(2001)
Circulation
, vol.104
, pp. 1664-1669
-
-
Tian, R.1
Musi, N.2
D’Agostino, J.3
Hirshman, M.F.4
Goodyear, L.J.5
-
97
-
-
85089285052
-
Administration of SGLT2 inhibitor empagliflozin against TNF-α induced endothelial dysfunction in human venous and arterial endothelial cells
-
b, :,.4
-
Uthman L., Homayr A., Hollmann M. W., Zuurbier C. J., Weber N. C., (2018b). Administration of SGLT2 inhibitor empagliflozin against TNF-α induced endothelial dysfunction in human venous and arterial endothelial cells. FASEB J. 32:569.4.
-
(2018)
FASEB J
, vol.32
, Issue.569
-
-
Uthman, L.1
Homayr, A.2
Hollmann, M.W.3
Zuurbier, C.J.4
Weber, N.C.5
-
98
-
-
85102877689
-
Empagliflozin effects on ischemic contracture and I/R injury in isolated mouse hearts perfused with or without insulin
-
c
-
Uthman L., Nederlof R., Eerbeek O., Baartscheer A., Buchholtz N., Coronel R., et al. (2018c). Empagliflozin effects on ischemic contracture and I/R injury in isolated mouse hearts perfused with or without insulin. FASEB J. 32:lb292.
-
(2018)
FASEB J
, vol.32
, Issue.lb292
-
-
Uthman, L.1
Nederlof, R.2
Eerbeek, O.3
Baartscheer, A.4
Buchholtz, N.5
Coronel, R.6
-
99
-
-
37349080234
-
Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension
-
18071071
-
Van Heerebeek L., Hamdani N., Handoko M. L., Falcao-Pires I., Musters R. J., Kupreishvili K., et al. (2008). Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension. Circulation 117 43–51. 10.1161/CIRCULATIONAHA.107.728550 18071071
-
(2008)
Circulation
, vol.117
, pp. 43-51
-
-
Van Heerebeek, L.1
Hamdani, N.2
Handoko, M.L.3
Falcao-Pires, I.4
Musters, R.J.5
Kupreishvili, K.6
-
100
-
-
85010903512
-
Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart
-
28128227
-
Van Steenbergen A., Balteau M., Ginion A., Ferté L., Battault S., Ravenstein C. D., et al. (2017). Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart. Sci. Rep. 7:41166. 10.1038/srep41166 28128227
-
(2017)
Sci. Rep
, vol.7
, Issue.41166
-
-
Van Steenbergen, A.1
Balteau, M.2
Ginion, A.3
Ferté, L.4
Battault, S.5
Ravenstein, C.D.6
-
101
-
-
85034611092
-
Molecular mechanisms of cardiac pathology in diabetes – Experimental insights
-
29109032
-
Varma U., Koutsifeli P., Benson V. L., Mellor K. M., Delbridge L. M. D., (2018). Molecular mechanisms of cardiac pathology in diabetes – Experimental insights. Biochim. Biophys. Acta 1864 1949–1959. 10.1016/j.bbadis.2017.10.035 29109032
-
(2018)
Biochim. Biophys. Acta
, vol.1864
, pp. 1949-1959
-
-
Varma, U.1
Koutsifeli, P.2
Benson, V.L.3
Mellor, K.M.4
Delbridge, L.M.D.5
-
102
-
-
0029834439
-
Protective effects of extracellular acidosis and blockade of sodium/hydrogen ion exchange during recovery from metabolic inhibition in neuronal tissue culture
-
8931470
-
Vornov J. J., Thomas A. G., Jo D., (1996). Protective effects of extracellular acidosis and blockade of sodium/hydrogen ion exchange during recovery from metabolic inhibition in neuronal tissue culture. J. Neurochem. 67 2379–2389. 10.1046/j.1471-4159.1996.67062379.x 8931470
-
(1996)
J. Neurochem
, vol.67
, pp. 2379-2389
-
-
Vornov, J.J.1
Thomas, A.G.2
Jo, D.3
-
103
-
-
84943234625
-
+-D-glucose cotransporters SGLT1 and SGLT2 in human kidney and of SGLT1 in human small intestine, liver, lung, and heart
-
25304002
-
+-D-glucose cotransporters SGLT1 and SGLT2 in human kidney and of SGLT1 in human small intestine, liver, lung, and heart. Pflugers Arch. Eur. J. Physiol. 467 1881–1898. 10.1007/s00424-014-1619-7 25304002
-
(2015)
Pflugers Arch. Eur. J. Physiol
, vol.467
, pp. 1881-1898
-
-
Vrhovac, I.1
Eror, D.B.2
Klessen, D.3
Burger, C.4
Breljak, D.5
Kraus, O.6
-
104
-
-
85054076360
-
Involvement of NLRP3 inflammasome in the impacts of sodium and potassium on insulin resistance in normotensive Asians
-
29359681
-
Wan Z., Wen W., Ren K., Zhou D., Liu J., Wu Y., et al. (2018). Involvement of NLRP3 inflammasome in the impacts of sodium and potassium on insulin resistance in normotensive Asians. Br. J. Nutr. 119 228–237. 10.1017/S0007114517002926 29359681
-
(2018)
Br. J. Nutr
, vol.119
, pp. 228-237
-
-
Wan, Z.1
Wen, W.2
Ren, K.3
Zhou, D.4
Liu, J.5
Wu, Y.6
-
105
-
-
54149092601
-
+ exchanger is required for hyperglycaemia- induced endothelial dysfunction via calcium-dependent calpain
-
18591204
-
+ exchanger is required for hyperglycaemia- induced endothelial dysfunction via calcium-dependent calpain. Cardiovasc. Res. 80 255–262. 10.1093/cvr/cvn179 18591204
-
(2008)
Cardiovasc. Res
, vol.80
, pp. 255-262
-
-
Wang, S.1
Peng, Q.2
Zhang, J.3
Liu, L.4
-
107
-
-
85018253813
-
SGLT-2 inhibition with dapagliflozin reduces the activation of the Nlrp3/ASC inflammasome and attenuates the development of diabetic cardiomyopathy in mice with type 2 diabetes. further augmentation of the effects with saxagliptin, a DPP4 inhibitor
-
28447181
-
Ye Y., Bajaj M., Yang H. C., Perez-Polo J. R., Birnbaum Y., (2017). SGLT-2 inhibition with dapagliflozin reduces the activation of the Nlrp3/ASC inflammasome and attenuates the development of diabetic cardiomyopathy in mice with type 2 diabetes. further augmentation of the effects with saxagliptin, a DPP4 inhibitor. Cardiovasc. Drugs Ther. 31 119–132. 10.1007/s10557-017-6725-2 28447181
-
(2017)
Cardiovasc. Drugs Ther
, vol.31
, pp. 119-132
-
-
Ye, Y.1
Bajaj, M.2
Yang, H.C.3
Perez-Polo, J.R.4
Birnbaum, Y.5
-
109
-
-
0035890319
-
+ exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction11This manuscript is dedicated to the memory of Karl-Ludwig Neuhaus (1944–2000)
-
+ exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction11This manuscript is dedicated to the memory of Karl-Ludwig Neuhaus (1944–2000). J. Am. Coll. Cardiol. 38 E1644–E1650. 10.1016/S0735-1097(01)01608-4
-
(2001)
J. Am. Coll. Cardiol
, vol.38
, pp. E1644-E1650
-
-
Zeymer, U.1
Suryapranata, H.2
Monassier, J.P.3
Opolski, G.4
Davies, J.5
Rasmanis, G.6
-
110
-
-
85039943841
-
Empagliflozin rescues diabetic myocardial microvascular injury via AMPK-mediated inhibition of mitochondrial fission
-
29306791
-
Zhou H., Wang S., Zhu P., Hu S., Chen Y., Ren J., (2018). Empagliflozin rescues diabetic myocardial microvascular injury via AMPK-mediated inhibition of mitochondrial fission. Redox Biol. 15 335–346. 10.1016/j.redox.2017.12.019 29306791
-
(2018)
Redox Biol
, vol.15
, pp. 335-346
-
-
Zhou, H.1
Wang, S.2
Zhu, P.3
Hu, S.4
Chen, Y.5
Ren, J.6
-
112
-
-
84944800184
-
Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes
-
26378978
-
Zinman B., Wanner C., Lachin J. M., Fitchett D., Bluhmki E., Hantel S., et al. (2015). Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N. Engl. J. Med. 373 2117–2128. 10.1056/NEJMoa1504720 26378978
-
(2015)
N. Engl. J. Med
, vol.373
, pp. 2117-2128
-
-
Zinman, B.1
Wanner, C.2
Lachin, J.M.3
Fitchett, D.4
Bluhmki, E.5
Hantel, S.6
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