Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation

Nature

Volumn 502, Issue 7471, 2013, Pages 372-376

  Erickson, Jeffrey R ^a,b   Pereira, Laetitia ^a   Wang, Lianguo ^a   Han, Guanghui ^c   Ferguson, Amanda ^a   Dao, Khanha ^a   Copeland, Ronald J ^c   Despa, Florin ^a,d   Hart, Gerald W ^c   Ripplinger, Crystal M ^a   Bers, Donald M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; GLUCOSE;

BRAIN; DIABETES; ENZYME; GLUCOSE; MEMORY; PROTEIN;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARRHYTHMOGENESIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DIABETES MELLITUS; ENZYME ACTIVATION; ENZYME MODIFICATION; FEMALE; GLYCOSYLATION; HEART ARRHYTHMIA; HEART MUSCLE CELL; HUMAN; HUMAN TISSUE; INTRACELLULAR SIGNALING; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SARCOPLASMIC RETICULUM;

ACETYLGLUCOSAMINE; ANIMALS; ARRHYTHMIAS, CARDIAC; BENZYLAMINES; BRAIN; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; DIABETES COMPLICATIONS; DIAZOOXONORLEUCINE; ENZYME ACTIVATION; GLUCOSE; GLYCOSYLATION; HUMANS; HYPERGLYCEMIA; MICE; MYOCARDIUM; MYOCYTES, CARDIAC; RATS; SARCOPLASMIC RETICULUM; SULFONAMIDES;

ANIMALIA; RATTUS;

EID: 84885863770     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature12537     Document Type: Article

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