메뉴 건너뛰기




Volumn 400, Issue 1-2, 2015, Pages 57-68

Dapagliflozin reduces the amplitude of shortening and Ca2+ transient in ventricular myocytes from streptozotocin-induced diabetic rats

Author keywords

Dapagliflozin; Diabetes mellitus; SGLT2 inhibitors; Streptozotocin induced diabetic rats; Ventricular myocytes

Indexed keywords

CALCIUM; DAPAGLIFLOZIN; STREPTOZOCIN; 2-(3-(4-ETHOXYBENZYL)-4-CHLOROPHENYL)-6-HYDROXYMETHYLTETRAHYDRO-2H-PYRAN-3,4,5-TRIOL; BENZHYDRYL DERIVATIVE; GLUCOSE; GLUCOSE BLOOD LEVEL; GLUCOSIDE;

EID: 84922005208     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-014-2262-5     Document Type: Article
Times cited : (55)

References (40)
  • 1
    • 84922005286 scopus 로고    scopus 로고
    • Brussels, Belgium:
    • International Diabetes Federation (2013) ATLAS. 6th ed. Brussels, Belgium
    • (2013) ATLAS
  • 2
    • 21744461617 scopus 로고    scopus 로고
    • Glucose intolerance and associated factors in the multi-ethnic population of the United Arab Emirates: results of a national survey
    • COI: 1:STN:280:DC%2BD2Mzlt1KrtQ%3D%3D, PID: 16005369
    • Malik M, Bakir A, Saab BA, King H (2005) Glucose intolerance and associated factors in the multi-ethnic population of the United Arab Emirates: results of a national survey. Diabetes Res Clin Pract 69(2):188–195
    • (2005) Diabetes Res Clin Pract , vol.69 , Issue.2 , pp. 188-195
    • Malik, M.1    Bakir, A.2    Saab, B.A.3    King, H.4
  • 4
    • 3142680168 scopus 로고    scopus 로고
    • Impact of diabetes and previous myocardial infarction on long-term survival: 25-year mortality follow-up of primary screenees of the multiple risk factor intervention trial
    • PID: 15249353
    • Vaccaro O, Eberly LE, Neaton JD, Yang L, Riccardi G, Stamler J (2004) Impact of diabetes and previous myocardial infarction on long-term survival: 25-year mortality follow-up of primary screenees of the multiple risk factor intervention trial. Arch Intern Med 164(13):1438–1443
    • (2004) Arch Intern Med , vol.164 , Issue.13 , pp. 1438-1443
    • Vaccaro, O.1    Eberly, L.E.2    Neaton, J.D.3    Yang, L.4    Riccardi, G.5    Stamler, J.6
  • 5
    • 0030998588 scopus 로고    scopus 로고
    • Cardiac complications in non-insulin-dependent diabetes mellitus
    • COI: 1:STN:280:DyaK2s3ls1SltQ%3D%3D, PID: 9101398
    • Julien J (1997) Cardiac complications in non-insulin-dependent diabetes mellitus. J Diabetes Complicat 11:123–130
    • (1997) J Diabetes Complicat , vol.11 , pp. 123-130
    • Julien, J.1
  • 6
    • 0022551339 scopus 로고
    • Arrhythmia susceptibility and myocardial composition in diabetes. Influence of physical conditioning
    • COI: 1:CAS:528:DyaL28Xht1Omu7k%3D, PID: 3944264
    • Bakth S, Arena J, Lee W, Torres R, Haider B, Patel BC, Lyons MM, Regan TJ (1986) Arrhythmia susceptibility and myocardial composition in diabetes. Influence of physical conditioning. J Clin Investig 77(2):382–395
    • (1986) J Clin Investig , vol.77 , Issue.2 , pp. 382-395
    • Bakth, S.1    Arena, J.2    Lee, W.3    Torres, R.4    Haider, B.5    Patel, B.C.6    Lyons, M.M.7    Regan, T.J.8
  • 7
    • 0026064153 scopus 로고
    • Autonomic neuropathy, QT interval lengthening, and unexpected deaths in male diabetic patients
    • COI: 1:STN:280:DyaK3MzlslalsA%3D%3D, PID: 1884890
    • Ewing DJ, Boland O, Neilson JM, Cho CG, Clarke BF (1991) Autonomic neuropathy, QT interval lengthening, and unexpected deaths in male diabetic patients. Diabetologia 34(3):182–185
    • (1991) Diabetologia , vol.34 , Issue.3 , pp. 182-185
    • Ewing, D.J.1    Boland, O.2    Neilson, J.M.3    Cho, C.G.4    Clarke, B.F.5
  • 8
    • 0025608234 scopus 로고
    • Symptoms, cardiovascular risk profile and spontaneous ECG in paced patients: a five-year follow-up study
    • COI: 1:STN:280:DyaK3M7jtl2ltw%3D%3D, PID: 1704598
    • Grimm W, Langenfeld H, Maisch B, Kochsiek K (1990) Symptoms, cardiovascular risk profile and spontaneous ECG in paced patients: a five-year follow-up study. Pacing Clin Electrophysiol 13(12 Pt 2):2086–2090
    • (1990) Pacing Clin Electrophysiol , vol.13 , Issue.12 , pp. 2086-2090
    • Grimm, W.1    Langenfeld, H.2    Maisch, B.3    Kochsiek, K.4
  • 9
    • 27144461138 scopus 로고    scopus 로고
    • Increased prevalence of third-degree atrioventricular block in patients with type II diabetes mellitus
    • PID: 16236932
    • Movahed MR, Hashemzadeh M, Jamal MM (2005) Increased prevalence of third-degree atrioventricular block in patients with type II diabetes mellitus. Chest 128(4):2611–2614
    • (2005) Chest , vol.128 , Issue.4 , pp. 2611-2614
    • Movahed, M.R.1    Hashemzadeh, M.2    Jamal, M.M.3
  • 10
    • 3442878980 scopus 로고    scopus 로고
    • The prevalence, type and severity of cardiovascular disease in diabetic and non-diabetic patients: a matched-paired retrospective analysis using coronary angiography as the diagnostic tool
    • COI: 1:CAS:528:DC%2BD2cXkt1Wjsr0%3D, PID: 15362512
    • Fallow GD, Singh J (2004) The prevalence, type and severity of cardiovascular disease in diabetic and non-diabetic patients: a matched-paired retrospective analysis using coronary angiography as the diagnostic tool. Mol Cell Biochem 261(1–2):263–269
    • (2004) Mol Cell Biochem , vol.261 , Issue.1-2 , pp. 263-269
    • Fallow, G.D.1    Singh, J.2
  • 11
    • 79952721660 scopus 로고    scopus 로고
    • Quantitative PCR tissue expression profiling of the human SGLT2 gene and related family members
    • COI: 1:CAS:528:DC%2BC3MXhsVehtrzP, PID: 22127746
    • Chen J, Williams S, Ho S, Loraine H, Hagan D, Whaley JM, Feder JN (2010) Quantitative PCR tissue expression profiling of the human SGLT2 gene and related family members. Diabetes Ther 1(2):57–92
    • (2010) Diabetes Ther , vol.1 , Issue.2 , pp. 57-92
    • Chen, J.1    Williams, S.2    Ho, S.3    Loraine, H.4    Hagan, D.5    Whaley, J.M.6    Feder, J.N.7
  • 12
    • 70449729537 scopus 로고    scopus 로고
    • SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states
    • COI: 1:CAS:528:DC%2BD1MXhtFarsbjJ, PID: 19509029
    • Banerjee SK, McGaffin KR, Pastor-Soler NM, Ahmad F (2009) SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states. Cardiovasc Res 84(1):111–118
    • (2009) Cardiovasc Res , vol.84 , Issue.1 , pp. 111-118
    • Banerjee, S.K.1    McGaffin, K.R.2    Pastor-Soler, N.M.3    Ahmad, F.4
  • 13
    • 80052362968 scopus 로고    scopus 로고
    • Role of sodium-glucose cotransporter 2 (SGLT 2) inhibitors in the treatment of type 2 diabetes
    • COI: 1:CAS:528:DC%2BC3MXht1eqtLjM, PID: 21606218
    • Abdul-Ghani MA, Norton L, Defronzo RA (2011) Role of sodium-glucose cotransporter 2 (SGLT 2) inhibitors in the treatment of type 2 diabetes. Endocr Rev 32(4):515–531
    • (2011) Endocr Rev , vol.32 , Issue.4 , pp. 515-531
    • Abdul-Ghani, M.A.1    Norton, L.2    Defronzo, R.A.3
  • 14
    • 84869745717 scopus 로고    scopus 로고
    • Systematic review of SGLT2 receptor inhibitors in dual or triple therapy in type 2 diabetes
    • PID: 23087012
    • Clar C, Gill JA, Court R, Waugh N (2012) Systematic review of SGLT2 receptor inhibitors in dual or triple therapy in type 2 diabetes. BMJ Open 2(5):e001007
    • (2012) BMJ Open , vol.2 , Issue.5 , pp. e001007
    • Clar, C.1    Gill, J.A.2    Court, R.3    Waugh, N.4
  • 15
    • 84860183617 scopus 로고    scopus 로고
    • A novel approach to control hyperglycemia in type 2 diabetes: sodium glucose co-transport (SGLT) inhibitors: systematic review and meta-analysis of randomized trials
    • COI: 1:CAS:528:DC%2BC38Xmt1Shsrc%3D, PID: 21495788
    • Musso G, Gambino R, Cassader M, Pagano G (2012) A novel approach to control hyperglycemia in type 2 diabetes: sodium glucose co-transport (SGLT) inhibitors: systematic review and meta-analysis of randomized trials. Ann Med 44(4):375–393
    • (2012) Ann Med , vol.44 , Issue.4 , pp. 375-393
    • Musso, G.1    Gambino, R.2    Cassader, M.3    Pagano, G.4
  • 16
    • 84874291673 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise
    • COI: 1:STN:280:DC%2BC3s3lvVWlsQ%3D%3D, PID: 23279307
    • Stenlof K, Cefalu WT, Kim KA, Alba M, Usiskin K, Tong C, Canovatchel W, Meininger G (2013) Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise. Diabetes Obes Metab 15(4):372–382
    • (2013) Diabetes Obes Metab , vol.15 , Issue.4 , pp. 372-382
    • Stenlof, K.1    Cefalu, W.T.2    Kim, K.A.3    Alba, M.4    Usiskin, K.5    Tong, C.6    Canovatchel, W.7    Meininger, G.8
  • 17
    • 84922006237 scopus 로고    scopus 로고
    • FDA Approves Invokana to treat type 2 diabetes. (2013) Food and Drug Administration
    • FDA Approves Invokana to treat type 2 diabetes. (2013) Food and Drug Administration
  • 19
    • 84861079280 scopus 로고    scopus 로고
    • Effects of SGLT2 inhibitors on cardiovascular outcomes
    • Foote C, Perkovic V, Neal B (2012) Effects of SGLT2 inhibitors on cardiovascular outcomes. Diabetes Vasc Dis Res 9(2):117–123
    • (2012) Diabetes Vasc Dis Res , vol.9 , Issue.2 , pp. 117-123
    • Foote, C.1    Perkovic, V.2    Neal, B.3
  • 20
    • 80052805929 scopus 로고    scopus 로고
    • Evaluation of the effect of dapagliflozin on cardiac repolarization: a thorough QT/QTc study
    • COI: 1:CAS:528:DC%2BC3MXhsVehtr%2FF, PID: 22127822
    • Carlson GF, Tou CK, Parikh S, Birmingham BK, Butler K (2011) Evaluation of the effect of dapagliflozin on cardiac repolarization: a thorough QT/QTc study. Diabetes Ther 2(3):123–132
    • (2011) Diabetes Ther , vol.2 , Issue.3 , pp. 123-132
    • Carlson, G.F.1    Tou, C.K.2    Parikh, S.3    Birmingham, B.K.4    Butler, K.5
  • 21
    • 0036448280 scopus 로고    scopus 로고
    • Effects of hyperosmotic shrinking on ventricular myocyte shortening and intracellular Ca(2+) in streptozotocin-induced diabetic rats
    • COI: 1:CAS:528:DC%2BD38XkvFKqsb4%3D, PID: 12111255
    • Howarth FC, Qureshi MA, White E (2002) Effects of hyperosmotic shrinking on ventricular myocyte shortening and intracellular Ca(2+) in streptozotocin-induced diabetic rats. Pflügers Arch 444(3):446–451
    • (2002) Pflügers Arch , vol.444 , Issue.3 , pp. 446-451
    • Howarth, F.C.1    Qureshi, M.A.2    White, E.3
  • 22
    • 0020376510 scopus 로고
    • Calcium tolerant ventricular myocytes prepared by preincubation in a “KB medium
    • COI: 1:STN:280:DyaL3s%2FptVakuw%3D%3D, PID: 7177773
    • Isenberg G, Klockner U (1982) Calcium tolerant ventricular myocytes prepared by preincubation in a “KB medium”. Pflügers Arch 395(1):6–18
    • (1982) Pflügers Arch , vol.395 , Issue.1 , pp. 6-18
    • Isenberg, G.1    Klockner, U.2
  • 23
    • 67349231868 scopus 로고    scopus 로고
    • L-type calcium channel current up-regulation by chronic stress is associated with increased alpha(1c) subunit expression in rat ventricular myocytes
    • PID: 18566917
    • Zhao Y, Xu J, Gong J, Qian L (2009) L-type calcium channel current up-regulation by chronic stress is associated with increased alpha(1c) subunit expression in rat ventricular myocytes. Cell Stress Chaperones 14(1):33–41
    • (2009) Cell Stress Chaperones , vol.14 , Issue.1 , pp. 33-41
    • Zhao, Y.1    Xu, J.2    Gong, J.3    Qian, L.4
  • 24
    • 0035853818 scopus 로고    scopus 로고
    • Microtubule disruption by colchicine reversibly enhances calcium signaling in intact rat cardiac myocytes
    • COI: 1:CAS:528:DC%2BD3MXjtlWrtbg%3D, PID: 11304499
    • Kerfant BG, Vassort G, Gomez AM (2001) Microtubule disruption by colchicine reversibly enhances calcium signaling in intact rat cardiac myocytes. Circ Res 88(7):E59–E65
    • (2001) Circ Res , vol.88 , Issue.7 , pp. E59-E65
    • Kerfant, B.G.1    Vassort, G.2    Gomez, A.M.3
  • 25
    • 77956031818 scopus 로고    scopus 로고
    • Effects of GH secretagogues on contractility and Ca2+ homeostasis of isolated adult rat ventricular myocytes
    • COI: 1:CAS:528:DC%2BC3cXhtF2qtrvM, PID: 20610573
    • Sun Q, Ma Y, Zhang L, Zhao YF, Zang WJ, Chen C (2010) Effects of GH secretagogues on contractility and Ca2+ homeostasis of isolated adult rat ventricular myocytes. Endocrinology 151(9):4446–4454
    • (2010) Endocrinology , vol.151 , Issue.9 , pp. 4446-4454
    • Sun, Q.1    Ma, Y.2    Zhang, L.3    Zhao, Y.F.4    Zang, W.J.5    Chen, C.6
  • 26
    • 79960697907 scopus 로고    scopus 로고
    • Structural lesions and changing pattern of expression of genes encoding cardiac muscle proteins are associated with ventricular myocyte dysfunction in type 2 diabetic Goto-Kakizaki rats fed a high-fat diet
    • COI: 1:CAS:528:DC%2BC3MXhtFahs7fI, PID: 21666035
    • Howarth FC, Qureshi MA, Sobhy ZH, Parekh K, Yammahi SR, Adrian TE, Adeghate E (2011) Structural lesions and changing pattern of expression of genes encoding cardiac muscle proteins are associated with ventricular myocyte dysfunction in type 2 diabetic Goto-Kakizaki rats fed a high-fat diet. Exp Physiol 96(8):765–777
    • (2011) Exp Physiol , vol.96 , Issue.8 , pp. 765-777
    • Howarth, F.C.1    Qureshi, M.A.2    Sobhy, Z.H.3    Parekh, K.4    Yammahi, S.R.5    Adrian, T.E.6    Adeghate, E.7
  • 27
    • 46749083348 scopus 로고    scopus 로고
    • Myofilament sensitivity to Ca2+ in ventricular myocytes from the Goto-Kakizaki diabetic rat
    • COI: 1:CAS:528:DC%2BD1cXnslKrurc%3D, PID: 18483759
    • Howarth FC, Qureshi MA (2008) Myofilament sensitivity to Ca2+ in ventricular myocytes from the Goto-Kakizaki diabetic rat. Mol Cell Biochem 315(1–2):69–74
    • (2008) Mol Cell Biochem , vol.315 , Issue.1-2 , pp. 69-74
    • Howarth, F.C.1    Qureshi, M.A.2
  • 29
    • 0029029280 scopus 로고
    • Fractional SR Ca release is regulated by trigger Ca and SR Ca content in cardiac myocytes
    • Bassani JW, Yuan WL, Bers DM (1995) Fractional SR Ca release is regulated by trigger Ca and SR Ca content in cardiac myocytes. Am J Physiol 37:C1313–C1319
    • (1995) Am J Physiol , vol.37 , pp. C1313-C1319
    • Bassani, J.W.1    Yuan, W.L.2    Bers, D.M.3
  • 30
    • 0033561135 scopus 로고    scopus 로고
    • Effect of the microtubule polymerizing agent taxol on contraction, Ca2+ transient and L-type Ca2+ current in rat ventricular myocytes
    • COI: 1:CAS:528:DyaK1MXjtVKqsr8%3D, PID: 10087341
    • Howarth FC, Calaghan SC, Boyett MR, White E (1999) Effect of the microtubule polymerizing agent taxol on contraction, Ca2+ transient and L-type Ca2+ current in rat ventricular myocytes. J Physiol 516(Pt 2):409–419
    • (1999) J Physiol , vol.516 , pp. 409-419
    • Howarth, F.C.1    Calaghan, S.C.2    Boyett, M.R.3    White, E.4
  • 31
    • 0029786943 scopus 로고    scopus 로고
    • A method for making rapid changes of superfusate whilst maintaining temperature at 37 degrees C
    • COI: 1:CAS:528:DyaK28XlsF2mur4%3D, PID: 8772145
    • Levi AJ, Hancox JC, Howarth FC, Croker J, Vinnicombe J (1996) A method for making rapid changes of superfusate whilst maintaining temperature at 37 degrees C. Pflügers Arch 432(5):930–937
    • (1996) Pflügers Arch , vol.432 , Issue.5 , pp. 930-937
    • Levi, A.J.1    Hancox, J.C.2    Howarth, F.C.3    Croker, J.4    Vinnicombe, J.5
  • 32
    • 84879799028 scopus 로고    scopus 로고
    • Effects of exercise training on excitation-contraction coupling and related mRNA expression in hearts of Goto-Kakizaki type 2 diabetic rats
    • COI: 1:CAS:528:DC%2BC3sXmslaju7c%3D, PID: 23620341
    • Salem KA, Qureshi MA, Sydorenko V, Parekh K, Jayaprakash P, Iqbal T, Singh J, Oz M, Adrian TE, Howarth FC (2013) Effects of exercise training on excitation-contraction coupling and related mRNA expression in hearts of Goto-Kakizaki type 2 diabetic rats. Mol Cell Biochem 380(1–2):83–96
    • (2013) Mol Cell Biochem , vol.380 , Issue.1-2 , pp. 83-96
    • Salem, K.A.1    Qureshi, M.A.2    Sydorenko, V.3    Parekh, K.4    Jayaprakash, P.5    Iqbal, T.6    Singh, J.7    Oz, M.8    Adrian, T.E.9    Howarth, F.C.10
  • 34
    • 0141640818 scopus 로고    scopus 로고
    • Human cardiomyocytes express high level of Na+/glucose cotransporter 1 (SGLT1)
    • COI: 1:CAS:528:DC%2BD3sXotlGmsrs%3D, PID: 14505350
    • Zhou L, Cryan EV, D’Andrea MR, Belkowski S, Conway BR, Demarest KT (2003) Human cardiomyocytes express high level of Na+/glucose cotransporter 1 (SGLT1). J Cell Biochem 90(2):339–346
    • (2003) J Cell Biochem , vol.90 , Issue.2 , pp. 339-346
    • Zhou, L.1    Cryan, E.V.2    D’Andrea, M.R.3    Belkowski, S.4    Conway, B.R.5    Demarest, K.T.6
  • 36
    • 34447626824 scopus 로고    scopus 로고
    • Effects of streptozotocin-induced diabetes on contraction and calcium transport in rat ventricular cardiomyocytes
    • COI: 1:CAS:528:DC%2BD2sXpsFehtw%3D%3D, PID: 17151303
    • Bracken N, Howarth FC, Singh J (2006) Effects of streptozotocin-induced diabetes on contraction and calcium transport in rat ventricular cardiomyocytes. Ann NY Acad Sci 1084:208–222
    • (2006) Ann NY Acad Sci , vol.1084 , pp. 208-222
    • Bracken, N.1    Howarth, F.C.2    Singh, J.3
  • 37
    • 3442901926 scopus 로고    scopus 로고
    • Voltage-dependence of contraction in streptozotocin-induced diabetic myocytes
    • COI: 1:CAS:528:DC%2BD2cXkt1WjsrY%3D, PID: 15362509
    • Bracken NK, Woodall AJ, Howarth FC, Singh J (2004) Voltage-dependence of contraction in streptozotocin-induced diabetic myocytes. Mol Cell Biochem 261(1–2):235–243
    • (2004) Mol Cell Biochem , vol.261 , Issue.1-2 , pp. 235-243
    • Bracken, N.K.1    Woodall, A.J.2    Howarth, F.C.3    Singh, J.4
  • 38
    • 0010452459 scopus 로고
    • Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state
    • COI: 1:CAS:528:DyaL2MXlsFylsQ%3D%3D, PID: 6093100
    • Bean BP (1984) Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state. Proc Natl Acad Sci USA 81:6388–6392
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 6388-6392
    • Bean, B.P.1
  • 39
    • 0030725008 scopus 로고    scopus 로고
    • Molecular mechanism of use-dependent calcium channel block by phenylalkylamines: role of inactivation
    • COI: 1:CAS:528:DyaK2sXnvFamtb8%3D, PID: 9371844
    • Hering S, Aczel S, Kraus RL, Berjukow S, Striessnig J, Timin EN (1997) Molecular mechanism of use-dependent calcium channel block by phenylalkylamines: role of inactivation. Proc Natl Acad Sci USA 94(24):13323–13328
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.24 , pp. 13323-13328
    • Hering, S.1    Aczel, S.2    Kraus, R.L.3    Berjukow, S.4    Striessnig, J.5    Timin, E.N.6
  • 40
    • 0021182780 scopus 로고
    • Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists
    • Hess P, Lansman JB, Tsien RW (1983) Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists. Nature 311:538–544
    • (1983) Nature , vol.311 , pp. 538-544
    • Hess, P.1    Lansman, J.B.2    Tsien, R.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.