Amiloride attenuates lipopolysaccharide-accelerated atherosclerosis via inhibition of NHE1-dependent endothelial cell apoptosis

Acta Pharmacologica Sinica

Volumn 34, Issue 2, 2013, Pages 231-238

  Cui, Gui Mei ^a   Zhao, Yu Xi ^a   Zhang, Na Na ^a   Liu, Zeng Shan ^a   Sun, Wan Chun ^a   Peng, Qi Sheng ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

amiloride; ApoE mice; atherosclerosis; BAPTA; calpain; human umbilical vein endothelial cell; intracellular free Ca2+ level; lipopolysaccharide; NHE1; ZLLal

Indexed keywords

AMILORIDE; CALCIUM ION; CALPAIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; SODIUM PROTON EXCHANGE PROTEIN 1;

APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; CALCIUM CELL LEVEL; COMPETITIVE INHIBITION; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LIPID DIET; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING;

AMILORIDE; ANIMALS; APOPTOSIS; ATHEROSCLEROSIS; CALCIUM; CALPAIN; CATION TRANSPORT PROTEINS; ENDOTHELIAL CELLS; EPITHELIAL SODIUM CHANNEL BLOCKERS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LIPOPOLYSACCHARIDES; MALE; MICE; PROTO-ONCOGENE PROTEINS C-BCL-2; SODIUM-HYDROGEN ANTIPORTER;

EID: 84873561998     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2012.155     Document Type: Article

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