SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states

Cardiovascular Research

Volumn 84, Issue 1, 2009, Pages 111-118

  Banerjee, Sanjay K ^a   McGaffin, Kenneth R ^a   Pastor Soler, Núria M ^b   Ahmad, Ferhaan ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Diabetes; Glucose; Insulin; Ischaemia; Leptin

Indexed keywords

INSULIN; LEPTIN; MESSENGER RNA; PHLORIZIN; SODIUM GLUCOSE COTRANSPORTER 1; GLUCOSE; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 4; SLC5A1 PROTEIN, HUMAN; SLC5A1 PROTEIN, MOUSE;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FUNCTIONAL STATUS; GLUCOSE TRANSPORT; HEALTH; HEART ASSIST DEVICE; HEART FAILURE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HUMAN; HUMAN TISSUE; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SARCOLEMMA; UPREGULATION; ANIMAL; C57BL MOUSE; CARDIOMYOPATHY; GENETICS; HEART MUSCLE; METABOLISM; MIDDLE AGED; PHYSIOLOGY;

ADULT; AGED; ANIMALS; CARDIOMYOPATHIES; FEMALE; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; GLUCOSE TRANSPORTER TYPE 4; HUMANS; INSULIN; LEPTIN; MALE; MICE; MICE, INBRED C57BL; MIDDLE AGED; MYOCARDIAL ISCHEMIA; MYOCARDIUM; MYOCYTES, CARDIAC; RNA, MESSENGER; SODIUM-GLUCOSE TRANSPORTER 1;

EID: 70449729537     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvp190     Document Type: Article

References (31)

1. Stanley WC, Recchia FA, Lopaschuk GD. Myocardial substrate metabolism in the normal and failing heart. Physiol Rev 2005;85:1093-1129.
2. Stanley WC, Lopaschuk GD, Hall JL, McCormack JG. Regulation of myo-cardial carbohydrate metabolism under normal and ischaemic conditions. Potential for pharmacological interventions. Cardiovasc Res 1997;33: 243-257.
3. Schwenk RW, Luiken JJ, Bonen A, Glatz JF. Regulation of sarcolemmal glucose and fatty acid transporters in cardiac disease. Cardiovasc Res 2008;79:249-258.
4. Wright EM, Hirsch JR, Loo DD, Zampighi GA. Regulation of Na+/glucose cotransporters. J Exp Biol 1997;200:287-293.
5. Turk E, Zabel B, Mundlos S, Dyer J, Wright EM. Glucose/galactose malab-sorption caused by a defect in the Na+/glucose cotransporter. Nature 1991;350:354-356.
6. Zhou L, Cryan EV, D'Andrea MR, Belkowski S, Conway BR, Demarest KT. Human cardiomyocytes express high level of Na+/glucose cotransporter 1 (SGLT1). J Cell Biochem 2003;90:339-346.
7. McGaffin KR, Sun CK, Rager JJ, Romano LC, Zou B, Mathier MA et al. Leptin signalling reduces the severity of cardiac dysfunction and remodelling after chronic ischaemic injury. Cardiovasc Res 2008;77:54-63.
8. Keck M, Romero-Aleshire MJ, Cai Q, Hoyer PB, Brooks HL. Hormonal status affects the progression of STZ-induced diabetes and diabetic renal damage in the VCD mouse model of menopause. Am J Physiol Renal Physiol 2007;293:F193-F199.
9. Kaibara A, Moshyedi A, Auffenberg T, Abouhamze A, Copeland EM 3rd, Kalra S et al. Leptin produces anorexia and weight loss without inducing an acute phase response or protein wasting. Am J Physiol 1998;274: R1518-R1525.
10. Banerjee SK, Ramani R, Saba S, Rager J, Tian R, Mathier MA et al. A PRKAG2 mutation causes biphasic changes in myocardial AMPK activity and does not protect against ischemia. Biochem Biophys Res Commun 2007;360:381-387.
11. Zhao H, Yakar S, Gavrilova O, Sun H, Zhang Y, Kim H et al. Phloridzin improves hyperglycemia but not hepatic insulin resistance in a transgenic mouse model of type 2 diabetes. Diabetes 2004;53:2901-2909.
12. Ahmad F, Banerjee SK, Lage ML, Huang XN, Smith SH, Saba S et al. The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy. PLoS ONE 2008;3:e2642.
13. Bowling N, Walsh RA, Song G, Estridge T, Sandusky GE, Fouts RL et al. Increased protein kinase C activity and expression of Ca2+-sensitive iso-forms in the failing human heart. Circulation 1999;99:384-391.
14. Pastor-Soler N, Bagnis C, Sabolic I, Tyszkowski R, McKee M, Van Hoek A et al. Aquaporin 9 expression along the male reproductive tract. Biol Reprod 2001;65:384-393.
15. Zhou M, Sevilla L, Vallega G, Chen P, Palacin M, Zorzano A et al. Insulin-dependent protein trafficking in skeletal muscle cells. Am J Physiol 1998; 275:E187-E196.
16. Pastor-Soler NM, Hallows KR, Smolak C, Gong F, Brown D, Breton S. Alkaline pH-and cAMP-induced V-ATPase membrane accumulation is mediated by protein kinase A in epididymal clear cells. Am J Physiol 2008;294:C488-C494.
17. Breton S, Tyszkowski R, Sabolic I, Brown D. Postnatal development of H+ ATPase (proton-pump)-rich cells in rat epididymis. Histochem Cell Biol 1999;111:97-105.
18. Brown D, Lydon J, McLaughlin M, Stuart-Tilley A, Tyszkowski R, Alper S. Antigen retrieval in cryostat tissue sections and cultured cells by treatment with sodium dodecyl sulfate (SDS). Histochem Cell Biol 1996;105: 261-267.
19. Runembert I, Queffeulou G, Federici P, Vrtovsnik F, Colucci-Guyon E, Babinet C et al. Vimentin affects localization and activity of sodium-glucose cotransporter SGLT1 in membrane rafts. J Cell Sci 2002;115: 713-724.
20. Wright EM, Hirayama BA, Loo DF. Active sugar transport in health and disease. J Intern Med 2007;261:32-43.
21. Saunders J, Mathewkutty S, Drazner MH, McGuire DK. Cardiomyopathy in type 2 diabetes: update on pathophysiological mechanisms. Herz 2008; 33:184-190.
22. Koepsell H, Spangenberg J. Function and presumed molecular structure of Na(+)-D-glucose cotransport systems. J Membr Biol 1994;138:1-11.
23. Giudicelli J, Bertrand MF, Bilski S, Tran TT, Poiree JC. Effect of cross-linkers on the structure and function of pig-renal sodium-glucose cotran-sporters after papain treatment. Biochem J 1998;330:733-736.
24. Veyhl M, Spangenberg J, Puschel B, Poppe R, Dekel C, Fritzsch G et al. Cloning of a membrane-associated protein which modifies activity and properties of the Na(+)-D-glucose cotransporter. J Biol Chem 1993; 268:25041-25053.
25. Elfeber K, Stumpel F, Gorboulev V, Mattig S, Deussen A, Kaissling B et al. Na(+)-D-glucose cotransporter in muscle capillaries increases glucose permeability. Biochem Biophys Res Commun 2004;314:301-305.
26. Stanley WC, Lopaschuk GD, McCormack JG. Regulation of energy substrate metabolism in the diabetic heart. Cardiovasc Res 1997;34:25-33.
27. Young LH, Renfu Y, Russell R, Hu X, Caplan M, Ren J et al. Low-flow ischemia leads to translocation of canine heart GLUT-4 and GLUT-1 glucose transporters to the sarcolemma in vivo. Circulation 1997;95:415-422.
28. Lopaschuk GD, Stanley WC. Glucose metabolism in the ischemic heart. Circulation 1997;95:313-315.
29. Turk E, Kerner CJ, Lostao MP, Wright EM. Membrane topology of the human Na+/glucose cotransporter SGLT1. J Biol Chem 1996;271: 1925-1934.
30. Hirsch JR, Loo DD, Wright EM. Regulation of Na+/glucose cotransporter expression by protein kinases in Xenopus laevis oocytes. J Biol Chem 1996;271:14740-14746.
31. Abel ED, Kaulbach HC, Tian R, Hopkins JC, Duffy J, Doetschman T et al. Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart. J Clin Invest 1999;104:1703-1714.