Inhibition of Na+-H+ exchange prevents hypertrophy, fibrosis, and heart failure in β1-adrenergic receptor transgenic mice

Circulation Research

Volumn 90, Issue 7, 2002, Pages 814-819

  Engelhardt, Stefan ^a   Hein, Lutz ^a   Keller, Ursula ^a   Klämbt, Kerstin ^a   Lohse, Martin J ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

adrenergic receptor; Cariporide; Heart failure; Na+ H+ exchanger; Transgenic mouse

Indexed keywords

BETA ADRENERGIC RECEPTOR; CARIPORIDE; MESSENGER RNA; PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FIBROSING ALVEOLITIS; HEART CATHETERIZATION; HEART FAILURE; HEART FUNCTION; HEART HYPERTROPHY; HEART LEFT VENTRICLE CONTRACTILITY; HEART LEFT VENTRICLE WALL; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; TRANSGENIC MOUSE;

ADMINISTRATION, ORAL; ANIMALS; BLOTTING, WESTERN; BODY WEIGHT; CARDIOMEGALY; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; ENZYME INHIBITORS; FIBROSIS; GENE EXPRESSION; GUANIDINES; HEART FAILURE, CONGESTIVE; HUMANS; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCARDIUM; ORGAN SIZE; RECEPTORS, ADRENERGIC, BETA-1; RNA, MESSENGER; SODIUM-HYDROGEN ANTIPORTER; SULFONES; VENTRICULAR DYSFUNCTION, LEFT;

EID: 0037134401     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000014966.97486.C0     Document Type: Article

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