-
1
-
-
0030002580
-
The progression from hypertension to congestive heart failure
-
Levy, D., Larson, M. G., Vasan, R. S., Kannel, W. B. & Ho, K. K. The progression from hypertension to congestive heart failure. JAMA 275, 1557-1562 (1996).
-
(1996)
JAMA
, vol.275
, pp. 1557-1562
-
-
Levy, D.1
Larson, M.G.2
Vasan, R.S.3
Kannel, W.B.4
Ho, K.K.5
-
2
-
-
0034713820
-
Left ventricular hypertrophy: Pathogenesis, detection, and prognosis
-
Lorell, B. H. & Carabello, B. A. Left ventricular hypertrophy: pathogenesis, detection, and prognosis. Circulation 102, 470-479 (2000).
-
(2000)
Circulation
, vol.102
, pp. 470-479
-
-
Lorell, B.H.1
Carabello, B.A.2
-
3
-
-
33748323383
-
Regulation of cardiac hypertrophy by intracellular signalling pathways
-
Heineke, J. & Molkentin, J. D. Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat. Rev. Mol. Cell Biol. 7, 589-600 (2006).
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
, pp. 589-600
-
-
Heineke, J.1
Molkentin, J.D.2
-
4
-
-
84873868258
-
Signaling effectors underlying pathologic growth and remodeling of the heart
-
van Berlo, J. H., Maillet, M. & Molkentin, J. D. Signaling effectors underlying pathologic growth and remodeling of the heart. J. Clin. Invest. 123, 37-45 (2013).
-
(2013)
J. Clin. Invest
, vol.123
, pp. 37-45
-
-
Van Berlo, J.H.1
Maillet, M.2
Molkentin, J.D.3
-
5
-
-
84940586899
-
Pathophysiology of cardiac hypertrophy and heart failure: Signaling pathways and novel therapeutic targets
-
Tham, Y. K., Bernardo, B. C., Ooi, J. Y., Weeks, K. L. & McMullen, J. R. Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets. Arch. Toxicol. 89, 1401-1438 (2015).
-
(2015)
Arch. Toxicol
, vol.89
, pp. 1401-1438
-
-
Tham, Y.K.1
Bernardo, B.C.2
Ooi, J.Y.3
Weeks, K.L.4
McMullen, J.R.5
-
6
-
-
63849301000
-
AMPK: Lessons from transgenic and knockout animals
-
Viollet, B. et al. AMPK: lessons from transgenic and knockout animals. Front. Biosci. 14, 19-44 (2009).
-
(2009)
Front. Biosci
, vol.14
, pp. 19-44
-
-
Viollet, B.1
-
7
-
-
84871899214
-
AMP-activated protein kinase in the control of cardiac metabolism and remodeling
-
Horman, S., Beauloye, C., Vanoverschelde, J. L. & Bertrand, L. AMP-activated protein kinase in the control of cardiac metabolism and remodeling. Curr. Heart Fail. Rep. 9, 164-173 (2012).
-
(2012)
Curr. Heart Fail. Rep
, vol.9
, pp. 164-173
-
-
Horman, S.1
Beauloye, C.2
Vanoverschelde, J.L.3
Bertrand, L.4
-
8
-
-
0036364274
-
Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes
-
Krause, U., Bertrand, L. & Hue, L. Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes. Eur. J. Biochem. 269, 3751-3759 (2002).
-
(2002)
Eur. J. Biochem
, vol.269
, pp. 3751-3759
-
-
Krause, U.1
Bertrand, L.2
Hue, L.3
-
9
-
-
0037143449
-
Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis
-
Horman, S. et al. Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis. Curr. Biol. 12, 1419-1423 (2002).
-
(2002)
Curr. Biol
, vol.12
, pp. 1419-1423
-
-
Horman, S.1
-
10
-
-
33847072201
-
AMP-activated protein kinase as a drug target
-
Hardie, D. G. AMP-activated protein kinase as a drug target. Annu. Rev. Pharmacol. Toxicol. 47, 185-210 (2007).
-
(2007)
Annu. Rev. Pharmacol. Toxicol
, vol.47
, pp. 185-210
-
-
Hardie, D.G.1
-
11
-
-
53049091294
-
Resveratrol inhibits cardiac hypertrophy via AMP-activated protein kinase and Akt
-
Chan, A. Y. et al. Resveratrol inhibits cardiac hypertrophy via AMP-activated protein kinase and Akt. J. Biol. Chem. 283, 24194-24201 (2008).
-
(2008)
J. Biol. Chem
, vol.283
, pp. 24194-24201
-
-
Chan, A.Y.1
-
12
-
-
3543008912
-
Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte
-
Chan, A. Y., Soltys, C. L., Young, M. E., Proud, C. G. & Dyck, J. R. Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte. J. Biol. Chem. 279, 32771-32779 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 32771-32779
-
-
Chan, A.Y.1
Soltys, C.L.2
Young, M.E.3
Proud, C.G.4
Dyck, J.R.5
-
13
-
-
33947574510
-
Long-term activation of adenosine monophosphate-activated protein kinase attenuates pressure-overload-induced cardiac hypertrophy
-
Li, H. L. et al. Long-term activation of adenosine monophosphate-activated protein kinase attenuates pressure-overload-induced cardiac hypertrophy. J. Cell. Biochem. 100, 1086-1099 (2007).
-
(2007)
J. Cell. Biochem
, vol.100
, pp. 1086-1099
-
-
Li, H.L.1
-
14
-
-
42149139467
-
Adiponectin protects against angiotensin II-induced cardiac fibrosis through activation of PPAR-alpha
-
Fujita, K. et al. Adiponectin protects against angiotensin II-induced cardiac fibrosis through activation of PPAR-alpha. Arterioscler. Thromb. Vasc. Biol. 28, 863-870 (2008).
-
(2008)
Arterioscler. Thromb. Vasc. Biol
, vol.28
, pp. 863-870
-
-
Fujita, K.1
-
15
-
-
79960046907
-
Metformin attenuates pressure overload-induced cardiac hypertrophy via AMPK activation
-
Fu, Y. N. et al. Metformin attenuates pressure overload-induced cardiac hypertrophy via AMPK activation. Acta Pharmacol. Sin. 32, 879-887 (2011).
-
(2011)
Acta Pharmacol. Sin
, vol.32
, pp. 879-887
-
-
Fu, Y.N.1
-
16
-
-
19944369735
-
Adiponectin-mediated modulation of hypertrophic signals in the heart
-
Shibata, R. et al. Adiponectin-mediated modulation of hypertrophic signals in the heart. Nat. Med. 10, 1384-1389 (2004).
-
(2004)
Nat. Med
, vol.10
, pp. 1384-1389
-
-
Shibata, R.1
-
17
-
-
79251495785
-
Metformin inhibits isoproterenol-induced cardiac hypertrophy in mice
-
Cha, H. N. et al. Metformin inhibits isoproterenol-induced cardiac hypertrophy in mice. Korean J. Physiol. Pharmacol. 14, 377-384 (2010).
-
(2010)
Korean J. Physiol. Pharmacol
, vol.14
, pp. 377-384
-
-
Cha, H.N.1
-
18
-
-
84993988689
-
OGlcNAcylation, enemy or ally during cardiac hypertrophy development Biochim
-
Mailleux, F., Gelinas, R., Beauloye, C., Horman, S. & Bertrand, L. OGlcNAcylation, enemy or ally during cardiac hypertrophy development Biochim. Biophys. Acta 1862, 2232-2243 (2016).
-
(2016)
Biophys. Acta
, vol.1862
, pp. 2232-2243
-
-
Mailleux, F.1
Gelinas, R.2
Beauloye, C.3
Horman, S.4
Bertrand, L.5
-
19
-
-
84880648662
-
O-GlcNAc cycling: A link between metabolism and chronic disease
-
Bond, M. R. & Hanover, J. A. O-GlcNAc cycling: A link between metabolism and chronic disease. Annu. Rev. Nutr. 33, 205-229 (2013).
-
(2013)
Annu. Rev. Nutr
, vol.33
, pp. 205-229
-
-
Bond, M.R.1
Hanover, J.A.2
-
20
-
-
85015624771
-
Cardiomyocyte Ogt limits ventricular dysfunction in mice following pressure overload without affecting hypertrophy
-
Dassanayaka, S. et al. Cardiomyocyte Ogt limits ventricular dysfunction in mice following pressure overload without affecting hypertrophy. Basic Res. Cardiol. 112, 23 (2017).
-
(2017)
Basic Res. Cardiol
, vol.112
, pp. 23
-
-
Dassanayaka, S.1
-
21
-
-
84896717178
-
O-GlcNAc and the cardiovascular system
-
Dassanayaka, S. & Jones, S. P. O-GlcNAc and the cardiovascular system. Pharmacol. Ther. 142, 62-71 (2014).
-
(2014)
Pharmacol. Ther
, vol.142
, pp. 62-71
-
-
Dassanayaka, S.1
Jones, S.P.2
-
22
-
-
84856634159
-
Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure
-
Lunde, I. G. et al. Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure. Physiol. Genom. 44, 162-172 (2012).
-
(2012)
Physiol. Genom
, vol.44
, pp. 162-172
-
-
Lunde, I.G.1
-
23
-
-
84861137573
-
O-GlcNAc signaling is essential for NFAT-mediated transcriptional reprogramming during cardiomyocyte hypertrophy
-
Facundo, H. T. et al. O-GlcNAc signaling is essential for NFAT-mediated transcriptional reprogramming during cardiomyocyte hypertrophy. Am. J. Physiol. Heart Circ. Physiol. 302, H2122-H2130 (2012).
-
(2012)
Am. J. Physiol. Heart Circ. Physiol
, vol.302
, pp. H2122-H2130
-
-
Facundo, H.T.1
-
24
-
-
33744514139
-
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome
-
Cool, B. et al. Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome. Cell Metab. 3, 403-416 (2006).
-
(2006)
Cell Metab
, vol.3
, pp. 403-416
-
-
Cool, B.1
-
25
-
-
36348998521
-
Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase
-
Goransson, O. et al. Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase. J. Biol. Chem. 282, 32549-32560 (2007).
-
(2007)
J. Biol. Chem
, vol.282
, pp. 32549-32560
-
-
Goransson, O.1
-
26
-
-
84901332717
-
A-769662 potentiates the effect of other AMPactivated protein kinase activators on cardiac glucose uptake
-
Timmermans, A. D. et al. A-769662 potentiates the effect of other AMPactivated protein kinase activators on cardiac glucose uptake. Am. J. Physiol. Heart Circ. Physiol. 306, H1619-H1630 (2014).
-
(2014)
Am. J. Physiol. Heart Circ. Physiol
, vol.306
, pp. H1619-H1630
-
-
Timmermans, A.D.1
-
27
-
-
84922582471
-
Effects of ERK1/2/PPARalpha/SCAD signal pathways on cardiomyocyte hypertrophy induced by insulin-like growth factor 1 and phenylephrine
-
Huang, Q. et al. Effects of ERK1/2/PPARalpha/SCAD signal pathways on cardiomyocyte hypertrophy induced by insulin-like growth factor 1 and phenylephrine. Life Sci. 124, 41-49 (2015).
-
(2015)
Life Sci
, vol.124
, pp. 41-49
-
-
Huang, Q.1
-
28
-
-
57749083482
-
Metabolic switch and hypertrophy of cardiomyocytes following treatment with angiotensin II are prevented by AMP-activated protein kinase
-
Stuck, B. J., Lenski, M., Bohm, M. & Laufs, U. Metabolic switch and hypertrophy of cardiomyocytes following treatment with angiotensin II are prevented by AMP-activated protein kinase. J. Biol. Chem. 283, 32562-32569 (2008).
-
(2008)
J. Biol. Chem
, vol.283
, pp. 32562-32569
-
-
Stuck, B.J.1
Lenski, M.2
Bohm, M.3
Laufs, U.4
-
29
-
-
55949114398
-
AMP activated protein kinase-alpha2 deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction in mice
-
Zhang, P. et al. AMP activated protein kinase-alpha2 deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction in mice. Hypertension 52, 918-924 (2008).
-
(2008)
Hypertension
, vol.52
, pp. 918-924
-
-
Zhang, P.1
-
30
-
-
0034535088
-
Extracellular signal-regulated kinase plays an essential role in hypertrophic agonists, endothelin-1 and phenylephrine-induced cardiomyocyte hypertrophy
-
Yue, T. L. et al. Extracellular signal-regulated kinase plays an essential role in hypertrophic agonists, endothelin-1 and phenylephrine-induced cardiomyocyte hypertrophy. J. Biol. Chem. 275, 37895-37901 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 37895-37901
-
-
Yue, T.L.1
-
31
-
-
0347320747
-
Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy
-
Wilkins, B. J. et al. Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy. Circ. Res. 94, 110-118 (2004).
-
(2004)
Circ. Res
, vol.94
, pp. 110-118
-
-
Wilkins, B.J.1
-
32
-
-
0036837672
-
Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth
-
Wilkins, B. J. et al. Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth. Mol. Cell Biol. 22, 7603-7613 (2002).
-
(2002)
Mol. Cell Biol
, vol.22
, pp. 7603-7613
-
-
Wilkins, B.J.1
-
33
-
-
46749127292
-
A769662, a novel activator of AMP-activated protein kinase, inhibits non-proteolytic components of the 26S proteasome by an AMPK-independent mechanism
-
Moreno, D., Knecht, E., Viollet, B. & Sanz, P. A769662, a novel activator of AMP-activated protein kinase, inhibits non-proteolytic components of the 26S proteasome by an AMPK-independent mechanism. FEBS Lett. 582, 2650-2654 (2008).
-
(2008)
FEBS Lett
, vol.582
, pp. 2650-2654
-
-
Moreno, D.1
Knecht, E.2
Viollet, B.3
Sanz, P.4
-
34
-
-
73449087698
-
AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase
-
Benziane, B. et al. AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase. Am. J. Physiol. Cell Physiol. 297, C1554-C1566 (2009).
-
(2009)
Am. J. Physiol. Cell Physiol
, vol.297
, pp. C1554-C1566
-
-
Benziane, B.1
-
35
-
-
85016157569
-
GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis
-
Zibrova, D. et al. GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis. Biochem. J. 474, 983-1001 (2017).
-
(2017)
Biochem. J
, vol.474
, pp. 983-1001
-
-
Zibrova, D.1
-
36
-
-
84880850374
-
O-GlcNAcylation involvement in high glucose-induced cardiac hypertrophy via ERK1/2 and cyclin D2
-
Ding, F. et al. O-GlcNAcylation involvement in high glucose-induced cardiac hypertrophy via ERK1/2 and cyclin D2. Amino. Acids 45, 339-349 (2013).
-
(2013)
Amino Acids
, vol.45
, pp. 339-349
-
-
Ding, F.1
-
37
-
-
77952290632
-
A new regulation of IL-6 production in adult cardiomyocytes by betaadrenergic and IL-1 beta receptors and induction of cellular hypertrophy by IL-6 trans-signalling
-
Szabo-Fresnais, N., Lefebvre, F., Germain, A., Fischmeister, R. & Pomerance, M. A new regulation of IL-6 production in adult cardiomyocytes by betaadrenergic and IL-1 beta receptors and induction of cellular hypertrophy by IL-6 trans-signalling. Cell Signal. 22, 1143-1152 (2010).
-
(2010)
Cell Signal
, vol.22
, pp. 1143-1152
-
-
Szabo-Fresnais, N.1
Lefebvre, F.2
Germain, A.3
Fischmeister, R.4
Pomerance, M.5
-
38
-
-
53449089289
-
AMPKalpha2 counteracts the development of cardiac hypertrophy induced by isoproterenol
-
Zarrinpashneh, E. et al. AMPKalpha2 counteracts the development of cardiac hypertrophy induced by isoproterenol. Biochem. Biophys. Res. Commun. 376, 677-681 (2008).
-
(2008)
Biochem. Biophys. Res. Commun
, vol.376
, pp. 677-681
-
-
Zarrinpashneh, E.1
-
39
-
-
84867581721
-
G(13)-mediated signaling pathway is required for pressure overload-induced cardiac remodeling and heart failure
-
Takefuji, M. et al. G(13)-mediated signaling pathway is required for pressure overload-induced cardiac remodeling and heart failure. Circulation 126, 1972-1982 (2012).
-
(2012)
Circulation
, vol.126
, pp. 1972-1982
-
-
Takefuji, M.1
-
40
-
-
79959385996
-
Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice
-
Xie, Z. et al. Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice. Diabetes 60, 1770-1778 (2011).
-
(2011)
Diabetes
, vol.60
, pp. 1770-1778
-
-
Xie, Z.1
-
41
-
-
84919615360
-
Metformin: From mechanisms of action to therapies
-
Foretz, M., Guigas, B., Bertrand, L., Pollak, M. & Viollet, B. Metformin: from mechanisms of action to therapies. Cell Metab. 20, 953-966 (2014).
-
(2014)
Cell Metab
, vol.20
, pp. 953-966
-
-
Foretz, M.1
Guigas, B.2
Bertrand, L.3
Pollak, M.4
Viollet, B.5
-
42
-
-
84938744834
-
Variability of mouse left ventricular function assessment by 11. 7 Tesla MRI
-
Vanhoutte, L. et al. Variability of mouse left ventricular function assessment by 11.7 Tesla MRI. J. Cardiovasc. Transl. Res. 8, 362-371 (2015).
-
(2015)
J. Cardiovasc. Transl. Res
, vol.8
, pp. 362-371
-
-
Vanhoutte, L.1
-
43
-
-
41749100066
-
Proposed regulation of gene expression by glucose in rodent heart
-
Young, M. E. et al. Proposed regulation of gene expression by glucose in rodent heart. Gene Regul. Syst. Bio 1, 251-262 (2007).
-
(2007)
Gene Regul. Syst. Bio
, vol.1
, pp. 251-262
-
-
Young, M.E.1
-
44
-
-
84936750919
-
Interplay between troponin T phosphorylation and ON-acetylglucosaminylation in ischaemic heart failure
-
Dubois-Deruy, E. et al. Interplay between troponin T phosphorylation and ON-acetylglucosaminylation in ischaemic heart failure. Cardiovasc. Res. 107, 56-65 (2015).
-
(2015)
Cardiovasc. Res
, vol.107
, pp. 56-65
-
-
Dubois-Deruy, E.1
-
45
-
-
62149127454
-
Beyond AICA riboside: In search of new specific AMPactivated protein kinase activators
-
Guigas, B. et al. Beyond AICA riboside: in search of new specific AMPactivated protein kinase activators. IUBMB Life. 61, 18-26 (2009).
-
(2009)
IUBMB Life
, vol.61
, pp. 18-26
-
-
Guigas, B.1
-
46
-
-
56049112796
-
Thienopyridone drugs are selective activators of AMPactivated protein kinase beta1-containing complexes
-
Scott, J. W. et al. Thienopyridone drugs are selective activators of AMPactivated protein kinase beta1-containing complexes. Chem. Biol. 15, 1220-1230 (2008).
-
(2008)
Chem. Biol
, vol.15
, pp. 1220-1230
-
-
Scott, J.W.1
-
47
-
-
84942940714
-
C-Myc alters substrate utilization and O-GlcNAc protein posttranslational modifications without altering cardiac function during early aortic constriction
-
Ledee, D. et al. c-Myc alters substrate utilization and O-GlcNAc protein posttranslational modifications without altering cardiac function during early aortic constriction. PLoS ONE 10, e0135262 (2015).
-
(2015)
PLoS ONE
, vol.10
, pp. e0135262
-
-
Ledee, D.1
-
48
-
-
84940750130
-
Cardiac LXRalpha protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization
-
Cannon, M. V. et al. Cardiac LXRalpha protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization. EMBO Mol. Med. 7, 1229-1243 (2015).
-
(2015)
EMBO Mol. Med
, vol.7
, pp. 1229-1243
-
-
Cannon, M.V.1
-
49
-
-
84870822727
-
Roles for the sarco-/endoplasmic reticulum in cardiac myocyte contraction, protein synthesis, and protein quality control
-
Glembotski, C. C. Roles for the sarco-/endoplasmic reticulum in cardiac myocyte contraction, protein synthesis, and protein quality control. Physiology 27, 343-350 (2012).
-
(2012)
Physiology
, vol.27
, pp. 343-350
-
-
Glembotski, C.C.1
-
50
-
-
70350482930
-
O-GlcNAc signaling attenuates ER stress-induced cardiomyocyte death
-
Ngoh, G. A., Hamid, T., Prabhu, S. D. & Jones, S. P. O-GlcNAc signaling attenuates ER stress-induced cardiomyocyte death. Am. J. Physiol. Heart Circ. Physiol. 297, H1711-H1719 (2009).
-
(2009)
Am. J. Physiol. Heart Circ. Physiol
, vol.297
, pp. H1711-H1719
-
-
Ngoh, G.A.1
Hamid, T.2
Prabhu, S.D.3
Jones, S.P.4
-
51
-
-
34147143863
-
Chronic hexosamine flux stimulates fatty acid oxidation by activating AMP-activated protein kinase in adipocytes
-
Luo, B. et al. Chronic hexosamine flux stimulates fatty acid oxidation by activating AMP-activated protein kinase in adipocytes. J. Biol. Chem. 282, 7172-7180 (2007).
-
(2007)
J. Biol. Chem
, vol.282
, pp. 7172-7180
-
-
Luo, B.1
-
52
-
-
45149095784
-
AMP-activated protein kinase and p38 MAPK activate O-GlcNAcylation of neuronal proteins during glucose deprivation
-
Cheung, W. D. & Hart, G. W. AMP-activated protein kinase and p38 MAPK activate O-GlcNAcylation of neuronal proteins during glucose deprivation. J. Biol. Chem. 283, 13009-13020 (2008).
-
(2008)
J. Biol. Chem
, vol.283
, pp. 13009-13020
-
-
Cheung, W.D.1
Hart, G.W.2
-
53
-
-
63649085232
-
Up-regulation of O-GlcNAc transferase with glucose deprivation in HepG2 cells is mediated by decreased hexosamine pathway flux
-
Taylor, R. P., Geisler, T. S., Chambers, J. H. & McClain, D. A. Up-regulation of O-GlcNAc transferase with glucose deprivation in HepG2 cells is mediated by decreased hexosamine pathway flux. J. Biol. Chem. 284, 3425-3432 (2009).
-
(2009)
J. Biol. Chem
, vol.284
, pp. 3425-3432
-
-
Taylor, R.P.1
Geisler, T.S.2
Chambers, J.H.3
McClain, D.A.4
-
54
-
-
84898613353
-
Cross-talk between two essential nutrient-sensitive enzymes: O-GlcNAc transferase (OGT) and AMP-activated protein kinase (AMPK)
-
Bullen, J. W. et al. Cross-talk between two essential nutrient-sensitive enzymes: O-GlcNAc transferase (OGT) and AMP-activated protein kinase (AMPK). J. Biol. Chem. 289, 10592-10606 (2014).
-
(2014)
J. Biol. Chem
, vol.289
, pp. 10592-10606
-
-
Bullen, J.W.1
-
55
-
-
60849124518
-
AMP-activated protein kinase phosphorylates glutamine: Fructose-6-phosphate amidotransferase 1 at Ser243 to modulate its enzymatic activity
-
Eguchi, S. et al. AMP-activated protein kinase phosphorylates glutamine: fructose-6-phosphate amidotransferase 1 at Ser243 to modulate its enzymatic activity. Genes Cells 14, 179-189 (2009).
-
(2009)
Genes Cells
, vol.14
, pp. 179-189
-
-
Eguchi, S.1
-
56
-
-
36048943979
-
Identification of a novel serine phosphorylation site in human glutamine:Fructose-6-phosphate amidotransferase isoform 1
-
Li, Y. et al. Identification of a novel serine phosphorylation site in human glutamine:fructose-6-phosphate amidotransferase isoform 1. Biochemistry 46, 13163-13169 (2007).
-
(2007)
Biochemistry
, vol.46
, pp. 13163-13169
-
-
Li, Y.1
-
57
-
-
33748062350
-
Hypertrophic growth in cardiac myocytes is mediated by Myc through a Cyclin D2-dependent pathway
-
Zhong, W. et al. Hypertrophic growth in cardiac myocytes is mediated by Myc through a Cyclin D2-dependent pathway. Embo J. 25, 3869-3879 (2006).
-
(2006)
Embo J
, vol.25
, pp. 3869-3879
-
-
Zhong, W.1
-
58
-
-
0029049198
-
C-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas
-
Chou, T. Y., Hart, G. W. & Dang, C. V. c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas. J. Biol. Chem. 270, 18961-18965 (1995).
-
(1995)
J. Biol. Chem
, vol.270
, pp. 18961-18965
-
-
Chou, T.Y.1
Hart, G.W.2
Dang, C.V.3
-
59
-
-
58149379890
-
O-linked GlcNAc modification of cardiac myofilament proteins: A novel regulator of myocardial contractile function
-
Ramirez-Correa, G. A. et al. O-linked GlcNAc modification of cardiac myofilament proteins: A novel regulator of myocardial contractile function. Circ. Res. 103, 1354-1358 (2008).
-
(2008)
Circ. Res
, vol.103
, pp. 1354-1358
-
-
Ramirez-Correa, G.A.1
-
60
-
-
84875210462
-
Cardiac OGlcNAcylation blunts autophagic signaling in the diabetic heart
-
Marsh, S. A., Powell, P. C., Dell'italia, L. J. & Chatham, J. C. Cardiac OGlcNAcylation blunts autophagic signaling in the diabetic heart. Life Sci. 92, 648-656 (2013).
-
(2013)
Life Sci
, vol.92
, pp. 648-656
-
-
Marsh, S.A.1
Powell, P.C.2
Dell'Italia, L.J.3
Chatham, J.C.4
-
61
-
-
79955442316
-
AMPK activation, a preventive therapeutic target in the transition from cardiac injury to heart failure
-
Beauloye, C., Bertrand, L., Horman, S. & Hue, L. AMPK activation, a preventive therapeutic target in the transition from cardiac injury to heart failure. Cardiovasc. Res. 90, 224-233 (2011).
-
(2011)
Cardiovasc. Res
, vol.90
, pp. 224-233
-
-
Beauloye, C.1
Bertrand, L.2
Horman, S.3
Hue, L.4
-
62
-
-
79959381299
-
Cross talk between O-GlcNAcylation and phosphorylation: Roles in signaling, transcription, and chronic disease
-
Hart, G. W., Slawson, C., Ramirez-Correa, G. & Lagerlof, O. Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease. Annu. Rev. Biochem. 80, 825-858 (2011).
-
(2011)
Annu. Rev. Biochem
, vol.80
, pp. 825-858
-
-
Hart, G.W.1
Slawson, C.2
Ramirez-Correa, G.3
Lagerlof, O.4
-
63
-
-
77949853349
-
Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation
-
Sanchez Canedo, C. et al. Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation. Am. J. Physiol. Endocrinol. Metab. 298, E761-E769 (2010).
-
(2010)
Am. J. Physiol. Endocrinol. Metab
, vol.298
, pp. E761-E769
-
-
Sanchez Canedo, C.1
-
64
-
-
33745684376
-
AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B
-
Bertrand, L. et al. AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B. Am. J. Physiol. Heart Circ. Physiol. 291, H239-H250 (2006).
-
(2006)
Am. J. Physiol. Heart Circ. Physiol
, vol.291
, pp. H239-H250
-
-
Bertrand, L.1
-
65
-
-
0025873338
-
Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy
-
Rockman, H. A. et al. Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy. Proc. Natl Acad. Sci. USA 88, 8277-8281 (1991).
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 8277-8281
-
-
Rockman, H.A.1
-
66
-
-
0041357130
-
Minimally invasive aortic banding in mice: Effects of altered cardiomyocyte insulin signaling during pressure overload
-
Hu, P. et al. Minimally invasive aortic banding in mice: effects of altered cardiomyocyte insulin signaling during pressure overload. Am. J. Physiol. Heart Circ. Physiol. 285, H1261-H1269 (2003).
-
(2003)
Am. J. Physiol. Heart Circ. Physiol
, vol.285
, pp. H1261-H1269
-
-
Hu, P.1
-
67
-
-
0038179586
-
Rosuvastatin decreases caveolin-1 and improves nitric oxidedependent heart rate and blood pressure variability in apolipoprotein E-/-mice in vivo
-
Pelat, M. et al. Rosuvastatin decreases caveolin-1 and improves nitric oxidedependent heart rate and blood pressure variability in apolipoprotein E-/-mice in vivo. Circulation 107, 2480-2486 (2003).
-
(2003)
Circulation
, vol.107
, pp. 2480-2486
-
-
Pelat, M.1
-
68
-
-
84904758023
-
Reduced scar maturation and contractility lead to exaggerated left ventricular dilation after myocardial infarction in mice lacking AMPKalpha1
-
Noppe, G. et al. Reduced scar maturation and contractility lead to exaggerated left ventricular dilation after myocardial infarction in mice lacking AMPKalpha1. J. Mol. Cell Cardiol. 74, 32-43 (2014).
-
(2014)
J. Mol. Cell Cardiol
, vol.74
, pp. 32-43
-
-
Noppe, G.1
|