A critical appraisal of amyloid-β-targeting therapies for Alzheimer disease

Nature Reviews Neurology

Volumn 15, Issue 2, 2019, Pages 73-88

  Panza, Francesco ^a,b   Lozupone, Madia ^a   Logroscino, Giancarlo ^a   Imbimbo, Bruno P ^c  

^a UNIVERSITY OF BARI   (Italy)

^b CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^c CHIESI FARMACEUTICI S P A   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADUCANUMAB; ALZHEIMER DISEASE VACCINE; AMYLOID BETA PROTEIN; ATABECESTAT; AVAGACESTAT; BAN 2401; BAPINEUZUMAB; BETA SECRETASE INHIBITOR; BEXAROTENE; CLIOQUINOL; CNP 520; CRENEZUMAB; ELENBECESTAT; EPIGALLOCATECHIN GALLATE; ETAZOLATE; ETRETIN; GANTENERUMAB; HOMOTAURINE; LANABECESTAT; MONOCLONAL ANTIBODY; PLACEBO; PONEZUMAB; SEMAGACESTAT; SOLANEZUMAB; TARENFLURBIL; TAU PROTEIN; THALIDOMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANUTIDE CRIDIFICAR; VERUBECESTAT; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; SECRETASE;

ADVERSE EVENT; ALZHEIMER DISEASE; ALZHEIMER DISEASE ASSESSMENT SCALE; ALZHEIMER DISEASE COOPERATIVE STUDY PRECLINICAL ALZHEIMER COGNITIVE COMPOSITE; ANTIBODY RESPONSE; CLINICAL DEMENTIA RATING; COGNITIVE DEFECT; DEMENTIA ASSESSMENT; DISEASE SEVERITY; DRUG BIOAVAILABILITY; DRUG DOSE TITRATION; DRUG SAFETY; DRUG TOLERABILITY; EDEMA; HUMAN; IMMUNOTHERAPY; MINI MENTAL STATE EXAMINATION; NEUROTOXICITY; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVIEW; VACCINE IMMUNOGENICITY; VASOGENIC EDEMA; VASOGENIC OEDEMA; ANIMAL; DRUG DELIVERY SYSTEM; METABOLISM; PROCEDURES;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANTIBODIES, MONOCLONAL, HUMANIZED; ASPARTIC ACID ENDOPEPTIDASES; DRUG DELIVERY SYSTEMS; HUMANS;

EID: 85059560378     PISSN: 17594758     EISSN: 17594766     Source Type: Journal    
DOI: 10.1038/s41582-018-0116-6     Document Type: Review

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