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Volumn 115, Issue 17, 2018, Pages 4483-4488

β-Amyloid accumulation in the human brain after one night of sleep deprivation

Author keywords

Alzheimer s disease; Beta amyloid; Glymphatic system; Hippocampus; Sleep

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; FLORBETABEN; APOE PROTEIN, HUMAN;

EID: 85045873784     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1721694115     Document Type: Article
Times cited : (559)

References (71)
  • 1
    • 84879651014 scopus 로고    scopus 로고
    • Neuroscience. Garbage truck of the brain
    • Nedergaard M (2013) Neuroscience. Garbage truck of the brain. Science 340: 1529–1530.
    • (2013) Science , vol.340 , pp. 1529-1530
    • Nedergaard, M.1
  • 2
    • 85028012974 scopus 로고    scopus 로고
    • Perivascular spaces, glymphatic dysfunction, and small vessel disease
    • Mestre H, Kostrikov S, Mehta RI, Nedergaard M (2017) Perivascular spaces, glymphatic dysfunction, and small vessel disease. Clin Sci (Lond) 131:2257–2274.
    • (2017) Clin Sci (Lond) , vol.131 , pp. 2257-2274
    • Mestre, H.1    Kostrikov, S.2    Mehta, R.I.3    Nedergaard, M.4
  • 3
    • 84885775321 scopus 로고    scopus 로고
    • Sleep drives metabolite clearance from the adult brain
    • Xie L, et al. (2013) Sleep drives metabolite clearance from the adult brain. Science 342: 373–377.
    • (2013) Science , vol.342 , pp. 373-377
    • Xie, L.1
  • 4
    • 72449161215 scopus 로고    scopus 로고
    • Amyloid-β dynamics are regulated by orexin and the sleep-wake cycle
    • Kang J-E, et al. (2009) Amyloid-β dynamics are regulated by orexin and the sleep-wake cycle. Science 326:1005–1007.
    • (2009) Science , vol.326 , pp. 1005-1007
    • Kang, J.-E.1
  • 5
    • 84926297916 scopus 로고    scopus 로고
    • Sleep interacts with aβ to modulate intrinsic neuronal excitability
    • Tabuchi M, et al. (2015) Sleep interacts with aβ to modulate intrinsic neuronal excitability. Curr Biol 25:702–712.
    • (2015) Curr Biol , vol.25 , pp. 702-712
    • Tabuchi, M.1
  • 6
    • 84890358370 scopus 로고    scopus 로고
    • Self-reported sleep and β-amyloid deposition in community-dwelling older adults
    • Spira AP, et al. (2013) Self-reported sleep and β-amyloid deposition in community-dwelling older adults. JAMA Neurol 70:1537–1543.
    • (2013) JAMA Neurol , vol.70 , pp. 1537-1543
    • Spira, A.P.1
  • 7
    • 84965079802 scopus 로고    scopus 로고
    • The relationship between sleep quality and brain amyloid burden
    • Brown BM, et al.; AIBL Research Group (2016) The relationship between sleep quality and brain amyloid burden. Sleep (Basel) 39:1063–1068.
    • (2016) Sleep (Basel) , vol.39 , pp. 1063-1068
    • Brown, B.M.1
  • 8
    • 84940467043 scopus 로고    scopus 로고
    • Amyloid burden is associated with self-reported sleep in nondemented late middle-aged adults
    • Sprecher KE, et al. (2015) Amyloid burden is associated with self-reported sleep in nondemented late middle-aged adults. Neurobiol Aging 36:2568–2576.
    • (2015) Neurobiol Aging , vol.36 , pp. 2568-2576
    • Sprecher, K.E.1
  • 9
    • 84877305911 scopus 로고    scopus 로고
    • Sleep quality and preclinical Alzheimer disease
    • Ju Y-ES, et al. (2013) Sleep quality and preclinical Alzheimer disease. JAMA Neurol 70: 587–593.
    • (2013) JAMA Neurol , vol.70 , pp. 587-593
    • Ju, Y.-E.S.1
  • 10
    • 84893829393 scopus 로고    scopus 로고
    • Sleep and Alzheimer disease pathology—A bidirectional relationship
    • Ju Y-ES, Lucey BP, Holtzman DM (2014) Sleep and Alzheimer disease pathology—A bidirectional relationship. Nat Rev Neurol 10:115–119.
    • (2014) Nat Rev Neurol , vol.10 , pp. 115-119
    • Ju, Y.-E.S.1    Lucey, B.P.2    Holtzman, D.M.3
  • 11
    • 84880759156 scopus 로고    scopus 로고
    • Neurotoxicity of amyloid β-protein: Synaptic and network dysfunction
    • Mucke L, Selkoe DJ (2012) Neurotoxicity of amyloid β-protein: Synaptic and network dysfunction. Cold Spring Harb Perspect Med 2:a006338.
    • (2012) Cold Spring Harb Perspect Med , vol.2 , pp. a006338
    • Mucke, L.1    Selkoe, D.J.2
  • 12
    • 84964600620 scopus 로고    scopus 로고
    • Is amyloid-β harmful to the brain? Insights from human imaging studies
    • Jagust W (2016) Is amyloid-β harmful to the brain? Insights from human imaging studies. Brain 139:23–30.
    • (2016) Brain , vol.139 , pp. 23-30
    • Jagust, W.1
  • 13
    • 85004010219 scopus 로고    scopus 로고
    • Sleep disturbance: An emerging opportunity for Alzheimer’s disease prevention?
    • Spira AP, Gottesman RF (2017) Sleep disturbance: An emerging opportunity for Alzheimer’s disease prevention? Int Psychogeriatr 29:529–531.
    • (2017) Int Psychogeriatr , vol.29 , pp. 529-531
    • Spira, A.P.1    Gottesman, R.F.2
  • 14
    • 84938800624 scopus 로고    scopus 로고
    • The effect of body posture on brain glymphatic transport
    • Lee H, et al. (2015) The effect of body posture on brain glymphatic transport. J Neurosci 35:11034–11044.
    • (2015) J Neurosci , vol.35 , pp. 11034-11044
    • Lee, H.1
  • 15
    • 84865123660 scopus 로고    scopus 로고
    • A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β
    • Iliff JJ, et al. (2012) A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β. Sci Transl Med 4:147ra111.
    • (2012) Sci Transl Med , vol.4 , pp. 147ra111
    • Iliff, J.J.1
  • 16
    • 84905994853 scopus 로고    scopus 로고
    • Effect of 1 night of total sleep deprivation on cerebrospinal fluid β-amyloid 42 in healthy middle-aged men: A randomized clinical trial
    • Ooms S, et al. (2014) Effect of 1 night of total sleep deprivation on cerebrospinal fluid β-amyloid 42 in healthy middle-aged men: A randomized clinical trial. JAMA Neurol 71:971–977.
    • (2014) JAMA Neurol , vol.71 , pp. 971-977
    • Ooms, S.1
  • 18
    • 85044517653 scopus 로고    scopus 로고
    • Blood-derived amyloid-β protein induces Alzheimer’s disease pathologies
    • October 31
    • Bu XL, et al. (October 31, 2017) Blood-derived amyloid-β protein induces Alzheimer’s disease pathologies. Mol Psychiatry, 10.1038/mp.2017.204.
    • (2017) Mol Psychiatry
    • Bu, X.L.1
  • 19
    • 34147183707 scopus 로고    scopus 로고
    • Role of the blood-brain barrier in the pathogenesis of Alzheimer’s disease
    • Deane R, Zlokovic BV (2007) Role of the blood-brain barrier in the pathogenesis of Alzheimer’s disease. Curr Alzheimer Res 4:191–197.
    • (2007) Curr Alzheimer Res , vol.4 , pp. 191-197
    • Deane, R.1    Zlokovic, B.V.2
  • 20
    • 85017569949 scopus 로고    scopus 로고
    • Sleep deprivation induced plasma amyloid-β transport disturbance in healthy young adults
    • Wei M, et al. (2017) Sleep deprivation induced plasma amyloid-β transport disturbance in healthy young adults. J Alzheimers Dis 57:899–906.
    • (2017) J Alzheimers Dis , vol.57 , pp. 899-906
    • Wei, M.1
  • 21
    • 85040963447 scopus 로고    scopus 로고
    • Effect of sleep on overnight CSF amyloid-β kinetics
    • December 8
    • Lucey BP, et al. (December 8, 2017) Effect of sleep on overnight CSF amyloid-β kinetics. Ann Neurol, 10.1002/ana.25117.
    • (2017) Ann Neurol
    • Lucey, B.P.1
  • 22
    • 10744232413 scopus 로고    scopus 로고
    • Imaging brain amyloid in Alzheimer’s disease with Pittsburgh compound-B
    • Klunk WE, et al. (2004) Imaging brain amyloid in Alzheimer’s disease with Pittsburgh compound-B. Ann Neurol 55:306–319.
    • (2004) Ann Neurol , vol.55 , pp. 306-319
    • Klunk, W.E.1
  • 23
    • 38149081191 scopus 로고    scopus 로고
    • Imaging of amyloid β in Alzheimer’s disease with 18F-BAY94-9172, a novel PET tracer: Proof of mechanism
    • Rowe CC, et al. (2008) Imaging of amyloid β in Alzheimer’s disease with 18F-BAY94-9172, a novel PET tracer: Proof of mechanism. Lancet Neurol 7:129–135.
    • (2008) Lancet Neurol , vol.7 , pp. 129-135
    • Rowe, C.C.1
  • 24
    • 84866025788 scopus 로고    scopus 로고
    • In vitro characterization of [18F]-florbetaben, an Aβ imaging radiotracer
    • Fodero-Tavoletti MT, et al. (2012) In vitro characterization of [18F]-florbetaben, an Aβ imaging radiotracer. Nucl Med Biol 39:1042–1048.
    • (2012) Nucl Med Biol , vol.39 , pp. 1042-1048
    • Fodero-Tavoletti, M.T.1
  • 25
    • 80051688987 scopus 로고    scopus 로고
    • Amyloid imaging with (18)F-florbetaben in Alzheimer disease and other dementias
    • Villemagne VL, et al. (2011) Amyloid imaging with (18)F-florbetaben in Alzheimer disease and other dementias. J Nucl Med 52:1210–1217.
    • (2011) J Nucl Med , vol.52 , pp. 1210-1217
    • Villemagne, V.L.1
  • 27
    • 84879980176 scopus 로고    scopus 로고
    • Amyloid tracers detect multiple binding sites in Alzheimer’s disease brain tissue
    • Ni R, Gillberg P-G, Bergfors A, Marutle A, Nordberg A (2013) Amyloid tracers detect multiple binding sites in Alzheimer’s disease brain tissue. Brain 136:2217–2227.
    • (2013) Brain , vol.136 , pp. 2217-2227
    • Ni, R.1    Gillberg, P.-G.2    Bergfors, A.3    Marutle, A.4    Nordberg, A.5
  • 28
    • 85008881282 scopus 로고    scopus 로고
    • Pittsburgh compound-B (PiB) binds amyloid β-protein protofibrils
    • Yamin G, Teplow DB (2017) Pittsburgh compound-B (PiB) binds amyloid β-protein protofibrils. J Neurochem 140:210–215.
    • (2017) J Neurochem , vol.140 , pp. 210-215
    • Yamin, G.1    Teplow, D.B.2
  • 29
    • 65249101314 scopus 로고    scopus 로고
    • MRI of hippocampal volume loss in early Alzheimer’s disease in relation to ApoE genotype and biomarkers
    • Alzheimer’s Disease Neuroimaging Initiative
    • Schuff N, et al.; Alzheimer’s Disease Neuroimaging Initiative (2009) MRI of hippocampal volume loss in early Alzheimer’s disease in relation to ApoE genotype and biomarkers. Brain 132:1067–1077.
    • (2009) Brain , vol.132 , pp. 1067-1077
    • Schuff, N.1
  • 30
    • 0034974107 scopus 로고    scopus 로고
    • Hippocampal formation glucose metabolism and volume losses in MCI and AD
    • De Santi S, et al. (2001) Hippocampal formation glucose metabolism and volume losses in MCI and AD. Neurobiol Aging 22:529–539.
    • (2001) Neurobiol Aging , vol.22 , pp. 529-539
    • De Santi, S.1
  • 31
    • 84991280080 scopus 로고    scopus 로고
    • Sleep: A novel mechanistic pathway, biomarker, and treatment target in the pathology of Alzheimer’s disease?
    • Mander BA, Winer JR, Jagust WJ, Walker MP (2016) Sleep: A novel mechanistic pathway, biomarker, and treatment target in the pathology of Alzheimer’s disease? Trends Neurosci 39:552–566.
    • (2016) Trends Neurosci , vol.39 , pp. 552-566
    • Mander, B.A.1    Winer, J.R.2    Jagust, W.J.3    Walker, M.P.4
  • 32
    • 85028326037 scopus 로고    scopus 로고
    • Slow wave sleep disruption increases cerebrospinal fluid amyloid-β levels
    • Ju YS, et al. (2017) Slow wave sleep disruption increases cerebrospinal fluid amyloid-β levels. Brain 140:2104–2111.
    • (2017) Brain , vol.140 , pp. 2104-2111
    • Ju, Y.S.1
  • 33
    • 0037172826 scopus 로고    scopus 로고
    • Phases of A β-deposition in the human brain and its relevance for the development of AD
    • Thal DR, Rüb U, Orantes M, Braak H (2002) Phases of A β-deposition in the human brain and its relevance for the development of AD. Neurology 58:1791–1800.
    • (2002) Neurology , vol.58 , pp. 1791-1800
    • Thal, D.R.1    Rüb, U.2    Orantes, M.3    Braak, H.4
  • 34
    • 85015599241 scopus 로고    scopus 로고
    • Neurodegenerative disorders: Neural synchronization in Alzheimer’s disease
    • Aron L, Yankner BA (2016) Neurodegenerative disorders: Neural synchronization in Alzheimer’s disease. Nature 540:207–208.
    • (2016) Nature , vol.540 , pp. 207-208
    • Aron, L.1    Yankner, B.A.2
  • 35
    • 79960809092 scopus 로고    scopus 로고
    • Neuronal activity regulates the regional vulnerability to amyloid-β deposition
    • Bero AW, et al. (2011) Neuronal activity regulates the regional vulnerability to amyloid-β deposition. Nat Neurosci 14:750–756.
    • (2011) Nat Neurosci , vol.14 , pp. 750-756
    • Bero, A.W.1
  • 36
    • 84931281803 scopus 로고    scopus 로고
    • Short-term sleep deprivation stimulates hippocampal neurogenesis in rats following global cerebral ischemia/reperfusion
    • Cheng O, et al. (2015) Short-term sleep deprivation stimulates hippocampal neurogenesis in rats following global cerebral ischemia/reperfusion. PLoS One 10:e0125877.
    • (2015) PLoS One , vol.10 , pp. e0125877
    • Cheng, O.1
  • 37
    • 84927610564 scopus 로고    scopus 로고
    • Detrimental role of prolonged sleep deprivation on adult neurogenesis
    • Fernandes C, et al. (2015) Detrimental role of prolonged sleep deprivation on adult neurogenesis. Front Cell Neurosci 9:140.
    • (2015) Front Cell Neurosci , vol.9 , pp. 140
    • Fernandes, C.1
  • 38
    • 79959772357 scopus 로고    scopus 로고
    • Human apoE isoforms differentially regulate brain amyloid-β peptide clearance
    • Castellano JM, et al. (2011) Human apoE isoforms differentially regulate brain amyloid-β peptide clearance. Sci Transl Med 3:89ra57.
    • (2011) Sci Transl Med , vol.3 , pp. 89ra57
    • Castellano, J.M.1
  • 39
    • 78049477126 scopus 로고    scopus 로고
    • Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer’s disease
    • Alzheimer’s Disease Neuroimaging Initiative
    • Jack CR, Jr, et al.; Alzheimer’s Disease Neuroimaging Initiative (2010) Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer’s disease. Brain 133: 3336–3348.
    • (2010) Brain , vol.133 , pp. 3336-3348
    • Jack, C.R.1
  • 40
    • 77956384880 scopus 로고    scopus 로고
    • 18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: A phase 2 trial
    • Vandenberghe R, et al. (2010) 18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: A phase 2 trial. Ann Neurol 68:319–329.
    • (2010) Ann Neurol , vol.68 , pp. 319-329
    • Vandenberghe, R.1
  • 41
    • 38949123792 scopus 로고    scopus 로고
    • Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease
    • Meyer-Luehmann M, et al. (2008) Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease. Nature 451:720–724.
    • (2008) Nature , vol.451 , pp. 720-724
    • Meyer-Luehmann, M.1
  • 42
    • 84860176568 scopus 로고    scopus 로고
    • Multicolor time-stamp reveals the dynamics and toxicity of amyloid deposition
    • Condello C, Schain A, Grutzendler J (2011) Multicolor time-stamp reveals the dynamics and toxicity of amyloid deposition. Sci Rep 1:19.
    • (2011) Sci Rep , vol.1 , pp. 19
    • Condello, C.1    Schain, A.2    Grutzendler, J.3
  • 43
    • 84882580016 scopus 로고    scopus 로고
    • Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical Aβ and pTau in a mouse model of Alzheimer’s disease
    • Rothman SM, Herdener N, Frankola KA, Mughal MR, Mattson MP (2013) Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical Aβ and pTau in a mouse model of Alzheimer’s disease. Brain Res 1529: 200–208.
    • (2013) Brain Res , vol.1529 , pp. 200-208
    • Rothman, S.M.1    Herdener, N.2    Frankola, K.A.3    Mughal, M.R.4    Mattson, M.P.5
  • 44
    • 85013642934 scopus 로고    scopus 로고
    • Chronic sleep restriction induces cognitive deficits and cortical beta-amyloid deposition in mice via BACE1-antisense activation
    • Zhao HY, et al. (2017) Chronic sleep restriction induces cognitive deficits and cortical beta-amyloid deposition in mice via BACE1-antisense activation. CNS Neurosci Ther 23:233–240.
    • (2017) CNS Neurosci Ther , vol.23 , pp. 233-240
    • Zhao, H.Y.1
  • 45
    • 84862512656 scopus 로고    scopus 로고
    • Using PET with 18F-AV-45 (florbetapir) to quantify brain amyloid load in a clinical environment
    • Camus V, et al. (2012) Using PET with 18F-AV-45 (florbetapir) to quantify brain amyloid load in a clinical environment. Eur J Nucl Med Mol Imaging 39:621–631.
    • (2012) Eur J Nucl Med Mol Imaging , vol.39 , pp. 621-631
    • Camus, V.1
  • 46
    • 84921326695 scopus 로고    scopus 로고
    • Blood-brain barrier breakdown in the aging human hippocampus
    • Montagne A, et al. (2015) Blood-brain barrier breakdown in the aging human hippocampus. Neuron 85:296–302.
    • (2015) Neuron , vol.85 , pp. 296-302
    • Montagne, A.1
  • 47
    • 84897977837 scopus 로고    scopus 로고
    • Microglia, neuroinflammation, and beta-amyloid protein in Alzheimer’s disease
    • Cai Z, Hussain MD, Yan L-J (2014) Microglia, neuroinflammation, and beta-amyloid protein in Alzheimer’s disease. Int J Neurosci 124:307–321.
    • (2014) Int J Neurosci , vol.124 , pp. 307-321
    • Cai, Z.1    Hussain, M.D.2    Yan, L.-J.3
  • 48
    • 84864818377 scopus 로고    scopus 로고
    • Sleep disturbance induces neuroinflammation and impairment of learning and memory
    • Zhu B, et al. (2012) Sleep disturbance induces neuroinflammation and impairment of learning and memory. Neurobiol Dis 48:348–355.
    • (2012) Neurobiol Dis , vol.48 , pp. 348-355
    • Zhu, B.1
  • 49
    • 84959017222 scopus 로고    scopus 로고
    • Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer’s disease
    • Sehlin D, et al. (2016) Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer’s disease. Nat Commun 7:10759.
    • (2016) Nat Commun , vol.7 , pp. 10759
    • Sehlin, D.1
  • 50
    • 33751111424 scopus 로고    scopus 로고
    • Frontal lobe metabolic decreases with sleep deprivation not totally reversed by recovery sleep
    • Wu JC, et al. (2006) Frontal lobe metabolic decreases with sleep deprivation not totally reversed by recovery sleep. Neuropsychopharmacology 31:2783–2792.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2783-2792
    • Wu, J.C.1
  • 51
    • 84922011676 scopus 로고    scopus 로고
    • How acute total sleep loss affects the attending brain: A meta-analysis of neuroimaging studies
    • Ma N, Dinges DF, Basner M, Rao H (2015) How acute total sleep loss affects the attending brain: A meta-analysis of neuroimaging studies. Sleep (Basel) 38:233–240.
    • (2015) Sleep (Basel) , vol.38 , pp. 233-240
    • Ma, N.1    Dinges, D.F.2    Basner, M.3    Rao, H.4
  • 52
    • 85045909921 scopus 로고    scopus 로고
    • Validation of non-invasive tracer kinetic analysis of 18F-florbeta-ben PET using a dual time-window acquisition protocol
    • Bullich S, et al. (2017) Validation of non-invasive tracer kinetic analysis of 18F-florbeta-ben PET using a dual time-window acquisition protocol. J Nucl Med jnumed.117.200964.
    • (2017) J Nucl Med Jnumed , vol.117 , pp. 200964
    • Bullich, S.1
  • 54
    • 85016804273 scopus 로고    scopus 로고
    • Sleep and adult neurogenesis: Implications for cognition and mood
    • eds Meerlo Benca RM, Abel T (Springer, Heidelberg, Germany)
    • Mueller AD, Meerlo P, McGinty D, Mistlberger RE (2013) Sleep and adult neurogenesis: Implications for cognition and mood. Sleep, Neuronal Plasticity and Brain Function, eds Meerlo P, Benca RM, Abel T (Springer, Heidelberg, Germany), pp 151–181.
    • (2013) Sleep, Neuronal Plasticity and Brain Function , pp. 151-181
    • Mueller, A.D.1    Meerlo, P.2    McGinty, D.3    Mistlberger, R.E.4
  • 55
    • 85016154603 scopus 로고    scopus 로고
    • Enhanced sleep reverses memory deficits and underlying pathology in Drosophila models of Alzheimer’s disease
    • Dissel S, et al. (2017) Enhanced sleep reverses memory deficits and underlying pathology in Drosophila models of Alzheimer’s disease. Neurobiol Sleep Circadian Rhythms 2:15–26.
    • (2017) Neurobiol Sleep Circadian Rhythms , vol.2 , pp. 15-26
    • Dissel, S.1
  • 56
    • 84880332607 scopus 로고    scopus 로고
    • The minimal preprocessing pipelines for the Human Connectome Project
    • Glasser MF, et al.; WU-Minn HCP Consortium (2013) The minimal preprocessing pipelines for the Human Connectome Project. Neuroimage 80:105–124.
    • (2013) Neuroimage , vol.80 , pp. 105-124
    • Glasser, M.F.1
  • 57
    • 84994851455 scopus 로고    scopus 로고
    • Cerebellar amyloid-β plaques: How frequent are they, and do they influence 18F-florbetaben SUV ratios?
    • Catafau AM, et al. (2016) Cerebellar amyloid-β plaques: How frequent are they, and do they influence 18F-florbetaben SUV ratios? J Nucl Med 57:1740–1745.
    • (2016) J Nucl Med , vol.57 , pp. 1740-1745
    • Catafau, A.M.1
  • 58
    • 85045877027 scopus 로고    scopus 로고
    • Optimal reference region to measure longitudinal amyloid-beta change with 18F-florbetaben PET
    • Bullich S, et al. (2017) Optimal reference region to measure longitudinal amyloid-beta change with 18F-florbetaben PET. J Nucl Med jnumed.116.187351.
    • (2017) J Nucl Med Jnumed , vol.116 , pp. 187351
    • Bullich, S.1
  • 59
    • 84938685099 scopus 로고    scopus 로고
    • Parametric imaging and quantitative analysis of the PET amyloid ligand [(18)F]flutemetamol
    • Heurling K, Buckley C, Van Laere K, Vandenberghe R, Lubberink M (2015) Parametric imaging and quantitative analysis of the PET amyloid ligand [(18)F]flutemetamol. Neuroimage 121:184–192.
    • (2015) Neuroimage , vol.121 , pp. 184-192
    • Heurling, K.1    Buckley, C.2    Van Laere, K.3    Vandenberghe, R.4    Lubberink, M.5
  • 61
    • 0031279782 scopus 로고    scopus 로고
    • Parametric imaging of ligand-receptor binding in PET using a simplified reference region model
    • Gunn RN, Lammertsma AA, Hume SP, Cunningham VJ (1997) Parametric imaging of ligand-receptor binding in PET using a simplified reference region model. Neuroimage 6: 279–287.
    • (1997) Neuroimage , vol.6 , pp. 279-287
    • Gunn, R.N.1    Lammertsma, A.A.2    Hume, S.P.3    Cunningham, V.J.4
  • 62
    • 0030468875 scopus 로고    scopus 로고
    • Simplified reference tissue model for PET receptor studies
    • Lammertsma AA, Hume SP (1996) Simplified reference tissue model for PET receptor studies. Neuroimage 4:153–158.
    • (1996) Neuroimage , vol.4 , pp. 153-158
    • Lammertsma, A.A.1    Hume, S.P.2
  • 63
    • 0029743481 scopus 로고    scopus 로고
    • Distribution volume ratios without blood sampling from graphical analysis of PET data
    • Logan J, et al. (1996) Distribution volume ratios without blood sampling from graphical analysis of PET data. J Cereb Blood Flow Metab 16:834–840.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 834-840
    • Logan, J.1
  • 64
    • 0024389366 scopus 로고
    • The pittsburgh sleep quality index: A new instrument for psychiatric practice and research
    • Buysse DJ, Reynolds CF, 3rd, Monk TH, Berman SR, Kupfer DJ (1989) The Pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research. Psychiatry Res 28:193–213.
    • (1989) Psychiatry Res , vol.28 , pp. 193-213
    • Buysse, D.J.1    Reynolds, C.F.2    Monk, T.H.3    Berman, S.R.4    Kupfer, D.J.5
  • 65
    • 85045898010 scopus 로고    scopus 로고
    • Sleep quality in young and middle age-period is associated with cerebral amyloid burden in cognitively normal elderly people
    • Choe YM, et al. (2016) Sleep quality in young and middle age-period is associated with cerebral amyloid burden in cognitively normal elderly people. Alzheimers Dement 12(Suppl):P171–P172.
    • (2016) Alzheimers Dement , vol.12 , pp. P171-P172
    • Choe, Y.M.1
  • 66
    • 85016224064 scopus 로고    scopus 로고
    • Prolonged sleep duration as a marker of early neuro-degeneration predicting incident dementia
    • Westwood AJ, et al. (2017) Prolonged sleep duration as a marker of early neuro-degeneration predicting incident dementia. Neurology 88:1172–1179.
    • (2017) Neurology , vol.88 , pp. 1172-1179
    • Westwood, A.J.1
  • 67
    • 84873722367 scopus 로고    scopus 로고
    • Apolipoprotein E and Alzheimer disease: Risk, mechanisms and therapy
    • erratum 2013
    • Liu C-C, Kanekiyo T, Xu H, Bu G (2013) Apolipoprotein E and Alzheimer disease: Risk, mechanisms and therapy. Nat Rev Neurol 9:106–118, and erratum (2013), 10.1038/ nmeurol.2013.32.
    • (2013) Nat Rev Neurol , vol.9 , pp. 106-118
    • Liu, C.-C.1    Kanekiyo, T.2    Xu, H.3    Bu, G.4
  • 68
    • 20444395466 scopus 로고    scopus 로고
    • Correlations between apolipoprotein E e4 gene dose and brain-imaging measurements of regional hypometabolism
    • Reiman EM, et al. (2005) Correlations between apolipoprotein E e4 gene dose and brain-imaging measurements of regional hypometabolism. Proc Natl Acad Sci USA 102:8299–8302.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 8299-8302
    • Reiman, E.M.1
  • 69
    • 77955036445 scopus 로고    scopus 로고
    • Association of CR1, CLU and PICALM with Alzheimer’s disease in a cohort of clinically characterized and neuropathologically verified individuals
    • Corneveaux JJ, et al. (2010) Association of CR1, CLU and PICALM with Alzheimer’s disease in a cohort of clinically characterized and neuropathologically verified individuals. Hum Mol Genet 19:3295–3301.
    • (2010) Hum Mol Genet , vol.19 , pp. 3295-3301
    • Corneveaux, J.J.1
  • 70
    • 0028998867 scopus 로고
    • Analysis of fMRI time-series revisited
    • Friston KJ, et al. (1995) Analysis of fMRI time-series revisited. Neuroimage 2:45–53.
    • (1995) Neuroimage , vol.2 , pp. 45-53
    • Friston, K.J.1
  • 71
    • 0031079260 scopus 로고    scopus 로고
    • Combining spatial extent and peak intensity to test for activations in functional imaging
    • Poline J-B, Worsley KJ, Evans AC, Friston KJ (1997) Combining spatial extent and peak intensity to test for activations in functional imaging. Neuroimage 5:83–96.
    • (1997) Neuroimage , vol.5 , pp. 83-96
    • Poline, J.-B.1    Worsley, K.J.2    Evans, A.C.3    Friston, K.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.