-
1
-
-
0033041179
-
Association of an extended haplotype in the tau gene with progressive supranuclear palsy
-
Baker, M., Litvan, I., Houlden, H., Adamson, J., Dickson, D., Perez-Tur, J., Hardy, J., Lynch, T., Bigio, E., Hutton, M., Association of an extended haplotype in the tau gene with progressive supranuclear palsy. Hum. Mol. Genet. 8 (1999), 711–715.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 711-715
-
-
Baker, M.1
Litvan, I.2
Houlden, H.3
Adamson, J.4
Dickson, D.5
Perez-Tur, J.6
Hardy, J.7
Lynch, T.8
Bigio, E.9
Hutton, M.10
-
2
-
-
80052157957
-
Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors
-
Ban, H., Nishishita, N., Fusaki, N., Tabata, T., Saeki, K., Shikamura, M., Takada, N., Inoue, M., Hasegawa, M., Kawamata, S., Nishikawa, S., Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors. Proc. Natl. Acad. Sci. USA 108 (2011), 14234–14239.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 14234-14239
-
-
Ban, H.1
Nishishita, N.2
Fusaki, N.3
Tabata, T.4
Saeki, K.5
Shikamura, M.6
Takada, N.7
Inoue, M.8
Hasegawa, M.9
Kawamata, S.10
Nishikawa, S.11
-
3
-
-
84957625003
-
Tau protein quantification in human cerebrospinal fluid by targeted mass spectrometry at high sequence coverage provides insights into its primary structure heterogeneity
-
Barthélemy, N.R., Fenaille, F., Hirtz, C., Sergeant, N., Schraen-Maschke, S., Vialaret, J., Buée, L., Gabelle, A., Junot, C., Lehmann, S., Becher, F., Tau protein quantification in human cerebrospinal fluid by targeted mass spectrometry at high sequence coverage provides insights into its primary structure heterogeneity. J. Proteome Res. 15 (2016), 667–676.
-
(2016)
J. Proteome Res.
, vol.15
, pp. 667-676
-
-
Barthélemy, N.R.1
Fenaille, F.2
Hirtz, C.3
Sergeant, N.4
Schraen-Maschke, S.5
Vialaret, J.6
Buée, L.7
Gabelle, A.8
Junot, C.9
Lehmann, S.10
Becher, F.11
-
4
-
-
85044112838
-
Tau hyperphosphorylation on T217 in cerebrospinal fluid is specifically associated to amyloid-β pathology
-
Barthélemy, N.R., Bateman, R.J., Marin, P., Becher, F., Sato, C., Lehmann, S., Gabelle, A., Tau hyperphosphorylation on T217 in cerebrospinal fluid is specifically associated to amyloid-β pathology. bioRxiv, 2017, 10.1101/226977.
-
(2017)
bioRxiv
-
-
Barthélemy, N.R.1
Bateman, R.J.2
Marin, P.3
Becher, F.4
Sato, C.5
Lehmann, S.6
Gabelle, A.7
-
5
-
-
33745920161
-
Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo
-
Bateman, R.J., Munsell, L.Y., Morris, J.C., Swarm, R., Yarasheski, K.E., Holtzman, D.M., Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo. Nat. Med. 12 (2006), 856–861.
-
(2006)
Nat. Med.
, vol.12
, pp. 856-861
-
-
Bateman, R.J.1
Munsell, L.Y.2
Morris, J.C.3
Swarm, R.4
Yarasheski, K.E.5
Holtzman, D.M.6
-
6
-
-
84865529158
-
Clinical and biomarker changes in dominantly inherited Alzheimer's disease
-
Bateman, R.J., Xiong, C., Benzinger, T.L.S., Fagan, A.M., Goate, A., Fox, N.C., Marcus, D.S., Cairns, N.J., Xie, X., Blazey, T.M., et al., Dominantly Inherited Alzheimer Network. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N. Engl. J. Med. 367 (2012), 795–804.
-
(2012)
N. Engl. J. Med.
, vol.367
, pp. 795-804
-
-
Bateman, R.J.1
Xiong, C.2
Benzinger, T.L.S.3
Fagan, A.M.4
Goate, A.5
Fox, N.C.6
Marcus, D.S.7
Cairns, N.J.8
Xie, X.9
Blazey, T.M.10
-
7
-
-
0027338266
-
Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding
-
Biernat, J., Gustke, N., Drewes, G., Mandelkow, E.M., Mandelkow, E., Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding. Neuron 11 (1993), 153–163.
-
(1993)
Neuron
, vol.11
, pp. 153-163
-
-
Biernat, J.1
Gustke, N.2
Drewes, G.3
Mandelkow, E.M.4
Mandelkow, E.5
-
8
-
-
56049128135
-
Pattern of Tau forms in CSF is altered in progressive supranuclear palsy
-
Borroni, B., Gardoni, F., Parnetti, L., Magno, L., Malinverno, M., Saggese, E., Calabresi, P., Spillantini, M.G., Padovani, A., Di Luca, M., Pattern of Tau forms in CSF is altered in progressive supranuclear palsy. Neurobiol. Aging 30 (2009), 34–40.
-
(2009)
Neurobiol. Aging
, vol.30
, pp. 34-40
-
-
Borroni, B.1
Gardoni, F.2
Parnetti, L.3
Magno, L.4
Malinverno, M.5
Saggese, E.6
Calabresi, P.7
Spillantini, M.G.8
Padovani, A.9
Di Luca, M.10
-
9
-
-
0029013727
-
Staging of Alzheimer's disease-related neurofibrillary changes
-
discussion 278–284
-
Braak, H., Braak, E., Staging of Alzheimer's disease-related neurofibrillary changes. Neurobiol. Aging 16 (1995), 271–278 discussion 278–284.
-
(1995)
Neurobiol. Aging
, vol.16
, pp. 271-278
-
-
Braak, H.1
Braak, E.2
-
10
-
-
84969172281
-
Tau and Aβ imaging, CSF measures, and cognition in Alzheimer's disease
-
Brier, M.R., Gordon, B., Friedrichsen, K., McCarthy, J., Stern, A., Christensen, J., Owen, C., Aldea, P., Su, Y., Hassenstab, J., et al. Tau and Aβ imaging, CSF measures, and cognition in Alzheimer's disease. Sci. Transl. Med., 8, 2016, 338ra66.
-
(2016)
Sci. Transl. Med.
, vol.8
, pp. 338ra66
-
-
Brier, M.R.1
Gordon, B.2
Friedrichsen, K.3
McCarthy, J.4
Stern, A.5
Christensen, J.6
Owen, C.7
Aldea, P.8
Su, Y.9
Hassenstab, J.10
-
11
-
-
84922785301
-
Human secreted tau increases amyloid-beta production
-
Bright, J., Hussain, S., Dang, V., Wright, S., Cooper, B., Byun, T., Ramos, C., Singh, A., Parry, G., Stagliano, N., Griswold-Prenner, I., Human secreted tau increases amyloid-beta production. Neurobiol. Aging 36 (2015), 693–709.
-
(2015)
Neurobiol. Aging
, vol.36
, pp. 693-709
-
-
Bright, J.1
Hussain, S.2
Dang, V.3
Wright, S.4
Cooper, B.5
Byun, T.6
Ramos, C.7
Singh, A.8
Parry, G.9
Stagliano, N.10
Griswold-Prenner, I.11
-
12
-
-
0033850407
-
Tau protein isoforms, phosphorylation and role in neurodegenerative disorders
-
Buée, L., Bussière, T., Buée-Scherrer, V., Delacourte, A., Hof, P.R., Tau protein isoforms, phosphorylation and role in neurodegenerative disorders. Brain Res. Brain Res. Rev. 33 (2000), 95–130.
-
(2000)
Brain Res. Brain Res. Rev.
, vol.33
, pp. 95-130
-
-
Buée, L.1
Bussière, T.2
Buée-Scherrer, V.3
Delacourte, A.4
Hof, P.R.5
-
13
-
-
34447096691
-
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration
-
Cairns, N.J., Bigio, E.H., Mackenzie, I.R.A., Neumann, M., Lee, V.M.-Y., Hatanpaa, K.J., White, C.L. 3rd, Schneider, J.A., Grinberg, L.T., Halliday, G., et al., Consortium for Frontotemporal Lobar Degeneration. Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathol. 114 (2007), 5–22.
-
(2007)
Acta Neuropathol.
, vol.114
, pp. 5-22
-
-
Cairns, N.J.1
Bigio, E.H.2
Mackenzie, I.R.A.3
Neumann, M.4
Lee, V.M.-Y.5
Hatanpaa, K.J.6
White, C.L.7
Schneider, J.A.8
Grinberg, L.T.9
Halliday, G.10
-
14
-
-
12644260802
-
The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology
-
Carmel, G., Mager, E.M., Binder, L.I., Kuret, J., The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology. J. Biol. Chem. 271 (1996), 32789–32795.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32789-32795
-
-
Carmel, G.1
Mager, E.M.2
Binder, L.I.3
Kuret, J.4
-
15
-
-
84864935106
-
Constitutive secretion of tau protein by an unconventional mechanism
-
Chai, X., Dage, J.L., Citron, M., Constitutive secretion of tau protein by an unconventional mechanism. Neurobiol. Dis. 48 (2012), 356–366.
-
(2012)
Neurobiol. Dis.
, vol.48
, pp. 356-366
-
-
Chai, X.1
Dage, J.L.2
Citron, M.3
-
16
-
-
84973572645
-
Pathological conformations involving the amino terminus of tau occur early in Alzheimer's disease and are differentially detected by monoclonal antibodies
-
Combs, B., Hamel, C., Kanaan, N.M., Pathological conformations involving the amino terminus of tau occur early in Alzheimer's disease and are differentially detected by monoclonal antibodies. Neurobiol. Dis. 94 (2016), 18–31.
-
(2016)
Neurobiol. Dis.
, vol.94
, pp. 18-31
-
-
Combs, B.1
Hamel, C.2
Kanaan, N.M.3
-
17
-
-
84936804907
-
In vivo kinetic approach reveals slow SOD1 turnover in the CNS
-
Crisp, M.J., Mawuenyega, K.G., Patterson, B.W., Reddy, N.C., Chott, R., Self, W.K., Weihl, C.C., Jockel-Balsarotti, J., Varadhachary, A.S., Bucelli, R.C., et al. In vivo kinetic approach reveals slow SOD1 turnover in the CNS. J. Clin. Invest. 125 (2015), 2772–2780.
-
(2015)
J. Clin. Invest.
, vol.125
, pp. 2772-2780
-
-
Crisp, M.J.1
Mawuenyega, K.G.2
Patterson, B.W.3
Reddy, N.C.4
Chott, R.5
Self, W.K.6
Weihl, C.C.7
Jockel-Balsarotti, J.8
Varadhachary, A.S.9
Bucelli, R.C.10
-
18
-
-
84857275902
-
Propagation of tau pathology in a model of early Alzheimer's disease
-
de Calignon, A., Polydoro, M., Suárez-Calvet, M., William, C., Adamowicz, D.H., Kopeikina, K.J., Pitstick, R., Sahara, N., Ashe, K.H., Carlson, G.A., et al. Propagation of tau pathology in a model of early Alzheimer's disease. Neuron 73 (2012), 685–697.
-
(2012)
Neuron
, vol.73
, pp. 685-697
-
-
de Calignon, A.1
Polydoro, M.2
Suárez-Calvet, M.3
William, C.4
Adamowicz, D.H.5
Kopeikina, K.J.6
Pitstick, R.7
Sahara, N.8
Ashe, K.H.9
Carlson, G.A.10
-
19
-
-
84929353239
-
Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms
-
Derisbourg, M., Leghay, C., Chiappetta, G., Fernandez-Gomez, F.-J., Laurent, C., Demeyer, D., Carrier, S., Buée-Scherrer, V., Blum, D., Vinh, J., et al. Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms. Sci. Rep., 5, 2015, 9659.
-
(2015)
Sci. Rep.
, vol.5
, pp. 9659
-
-
Derisbourg, M.1
Leghay, C.2
Chiappetta, G.3
Fernandez-Gomez, F.-J.4
Laurent, C.5
Demeyer, D.6
Carrier, S.7
Buée-Scherrer, V.8
Blum, D.9
Vinh, J.10
-
20
-
-
84947616699
-
Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus
-
Desikan, R.S., Schork, A.J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L.K., Holland, D., Brewer, J.B., Chen, C.-H., Thompson, W.K., et al., ADNI, ADGC, GERAD, CHARGE and IPDGC Investigators. Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus. Mol. Psychiatry 20 (2015), 1588–1595.
-
(2015)
Mol. Psychiatry
, vol.20
, pp. 1588-1595
-
-
Desikan, R.S.1
Schork, A.J.2
Wang, Y.3
Witoelar, A.4
Sharma, M.5
McEvoy, L.K.6
Holland, D.7
Brewer, J.B.8
Chen, C.-H.9
Thompson, W.K.10
-
21
-
-
84880838441
-
Antisense reduction of tau in adult mice protects against seizures
-
DeVos, S.L., Goncharoff, D.K., Chen, G., Kebodeaux, C.S., Yamada, K., Stewart, F.R., Schuler, D.R., Maloney, S.E., Wozniak, D.F., Rigo, F., et al. Antisense reduction of tau in adult mice protects against seizures. J. Neurosci. 33 (2013), 12887–12897.
-
(2013)
J. Neurosci.
, vol.33
, pp. 12887-12897
-
-
DeVos, S.L.1
Goncharoff, D.K.2
Chen, G.3
Kebodeaux, C.S.4
Yamada, K.5
Stewart, F.R.6
Schuler, D.R.7
Maloney, S.E.8
Wozniak, D.F.9
Rigo, F.10
-
22
-
-
85011390798
-
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy
-
DeVos, S.L., Miller, R.L., Schoch, K.M., Holmes, B.B., Kebodeaux, C.S., Wegener, A.J., Chen, G., Shen, T., Tran, H., Nichols, B., et al. Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy. Sci. Transl. Med. 9 (2017), 1–10.
-
(2017)
Sci. Transl. Med.
, vol.9
, pp. 1-10
-
-
DeVos, S.L.1
Miller, R.L.2
Schoch, K.M.3
Holmes, B.B.4
Kebodeaux, C.S.5
Wegener, A.J.6
Chen, G.7
Shen, T.8
Tran, H.9
Nichols, B.10
-
23
-
-
80855138704
-
Neuropathology of frontotemporal lobar degeneration-tau (FTLD-tau)
-
Dickson, D.W., Kouri, N., Murray, M.E., Josephs, K.A., Neuropathology of frontotemporal lobar degeneration-tau (FTLD-tau). J. Mol. Neurosci. 45 (2011), 384–389.
-
(2011)
J. Mol. Neurosci.
, vol.45
, pp. 384-389
-
-
Dickson, D.W.1
Kouri, N.2
Murray, M.E.3
Josephs, K.A.4
-
24
-
-
84937526707
-
Distinct neurodegenerative changes in an induced pluripotent stem cell model of frontotemporal dementia linked to mutant TAU protein
-
Ehrlich, M., Hallmann, A.-L., Reinhardt, P., Araúzo-Bravo, M.J., Korr, S., Röpke, A., Psathaki, O.E., Ehling, P., Meuth, S.G., Oblak, A.L., et al. Distinct neurodegenerative changes in an induced pluripotent stem cell model of frontotemporal dementia linked to mutant TAU protein. Stem Cell Reports 5 (2015), 83–96.
-
(2015)
Stem Cell Reports
, vol.5
, pp. 83-96
-
-
Ehrlich, M.1
Hallmann, A.-L.2
Reinhardt, P.3
Araúzo-Bravo, M.J.4
Korr, S.5
Röpke, A.6
Psathaki, O.E.7
Ehling, P.8
Meuth, S.G.9
Oblak, A.L.10
-
25
-
-
84897505354
-
Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease
-
Fagan, A.M., Xiong, C., Jasielec, M.S., Bateman, R.J., Goate, A.M., Benzinger, T.L.S., Ghetti, B., Martins, R.N., Masters, C.L., Mayeux, R., et al., Dominantly Inherited Alzheimer Network. Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease. Sci. Transl. Med., 6, 2014, 226ra30.
-
(2014)
Sci. Transl. Med.
, vol.6
, pp. 226ra30
-
-
Fagan, A.M.1
Xiong, C.2
Jasielec, M.S.3
Bateman, R.J.4
Goate, A.M.5
Benzinger, T.L.S.6
Ghetti, B.7
Martins, R.N.8
Masters, C.L.9
Mayeux, R.10
-
26
-
-
0026047799
-
Estrogen-enhanced neurite growth: evidence for a selective induction of Tau and stable microtubules
-
Ferreira, A., Caceres, A., Estrogen-enhanced neurite growth: evidence for a selective induction of Tau and stable microtubules. J. Neurosci. 11 (1991), 392–400.
-
(1991)
J. Neurosci.
, vol.11
, pp. 392-400
-
-
Ferreira, A.1
Caceres, A.2
-
27
-
-
18244406829
-
Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain
-
Fischl, B., Salat, D.H., Busa, E., Albert, M., Dieterich, M., Haselgrove, C., van der Kouwe, A., Killiany, R., Kennedy, D., Klaveness, S., et al. Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain. Neuron 33 (2002), 341–355.
-
(2002)
Neuron
, vol.33
, pp. 341-355
-
-
Fischl, B.1
Salat, D.H.2
Busa, E.3
Albert, M.4
Dieterich, M.5
Haselgrove, C.6
van der Kouwe, A.7
Killiany, R.8
Kennedy, D.9
Klaveness, S.10
-
28
-
-
85024396904
-
Cryo-EM structures of tau filaments from Alzheimer's disease
-
Fitzpatrick, A.W.P., Falcon, B., He, S., Murzin, A.G., Murshudov, G., Garringer, H.J., Crowther, R.A., Ghetti, B., Goedert, M., Scheres, S.H.W., Cryo-EM structures of tau filaments from Alzheimer's disease. Nature 547 (2017), 185–190.
-
(2017)
Nature
, vol.547
, pp. 185-190
-
-
Fitzpatrick, A.W.P.1
Falcon, B.2
He, S.3
Murzin, A.G.4
Murshudov, G.5
Garringer, H.J.6
Crowther, R.A.7
Ghetti, B.8
Goedert, M.9
Scheres, S.H.W.10
-
29
-
-
67649273927
-
Propagation of tau misfolding from the outside to the inside of a cell
-
Frost, B., Jacks, R.L., Diamond, M.I., Propagation of tau misfolding from the outside to the inside of a cell. J. Biol. Chem. 284 (2009), 12845–12852.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 12845-12852
-
-
Frost, B.1
Jacks, R.L.2
Diamond, M.I.3
-
30
-
-
84940707250
-
Distinct therapeutic mechanisms of Tau antibodies: promoting microglial clearance versus blocking neuronal uptake
-
Funk, K.E., Mirbaha, H., Jiang, H., Holtzman, D.M., Diamond, M.I., Distinct therapeutic mechanisms of Tau antibodies: promoting microglial clearance versus blocking neuronal uptake. J. Biol. Chem. 290 (2015), 21652–21662.
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 21652-21662
-
-
Funk, K.E.1
Mirbaha, H.2
Jiang, H.3
Holtzman, D.M.4
Diamond, M.I.5
-
31
-
-
84982947938
-
The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging
-
Gordon, B.A., Friedrichsen, K., Brier, M., Blazey, T., Su, Y., Christensen, J., Aldea, P., McConathy, J., Holtzman, D.M., Cairns, N.J., et al. The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging. Brain 139 (2016), 2249–2260.
-
(2016)
Brain
, vol.139
, pp. 2249-2260
-
-
Gordon, B.A.1
Friedrichsen, K.2
Brier, M.3
Blazey, T.4
Su, Y.5
Christensen, J.6
Aldea, P.7
McConathy, J.8
Holtzman, D.M.9
Cairns, N.J.10
-
32
-
-
20044381844
-
Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease
-
Guillozet-Bongaarts, A.L., Garcia-Sierra, F., Reynolds, M.R., Horowitz, P.M., Fu, Y., Wang, T., Cahill, M.E., Bigio, E.H., Berry, R.W., Binder, L.I., Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease. Neurobiol. Aging 26 (2005), 1015–1022.
-
(2005)
Neurobiol. Aging
, vol.26
, pp. 1015-1022
-
-
Guillozet-Bongaarts, A.L.1
Garcia-Sierra, F.2
Reynolds, M.R.3
Horowitz, P.M.4
Fu, Y.5
Wang, T.6
Cahill, M.E.7
Bigio, E.H.8
Berry, R.W.9
Binder, L.I.10
-
33
-
-
1642280378
-
Pseudophosphorylation of tau protein alters its ability for self-aggregation
-
Haase, C., Stieler, J.T., Arendt, T., Holzer, M., Pseudophosphorylation of tau protein alters its ability for self-aggregation. J. Neurochem. 88 (2004), 1509–1520.
-
(2004)
J. Neurochem.
, vol.88
, pp. 1509-1520
-
-
Haase, C.1
Stieler, J.T.2
Arendt, T.3
Holzer, M.4
-
34
-
-
72149123967
-
Total and phosphorylated tau protein as biological markers of Alzheimer's disease
-
Hampel, H., Blennow, K., Shaw, L.M., Hoessler, Y.C., Zetterberg, H., Trojanowski, J.Q., Total and phosphorylated tau protein as biological markers of Alzheimer's disease. Exp. Gerontol. 45 (2010), 30–40.
-
(2010)
Exp. Gerontol.
, vol.45
, pp. 30-40
-
-
Hampel, H.1
Blennow, K.2
Shaw, L.M.3
Hoessler, Y.C.4
Zetterberg, H.5
Trojanowski, J.Q.6
-
35
-
-
0031741247
-
New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry
-
Hanger, D.P., Betts, J.C., Loviny, T.L., Blackstock, W.P., Anderton, B.H., New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry. J. Neurochem. 71 (1998), 2465–2476.
-
(1998)
J. Neurochem.
, vol.71
, pp. 2465-2476
-
-
Hanger, D.P.1
Betts, J.C.2
Loviny, T.L.3
Blackstock, W.P.4
Anderton, B.H.5
-
36
-
-
0035910638
-
Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke
-
Hesse, C., Rosengren, L., Andreasen, N., Davidsson, P., Vanderstichele, H., Vanmechelen, E., Blennow, K., Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke. Neurosci. Lett. 297 (2001), 187–190.
-
(2001)
Neurosci. Lett.
, vol.297
, pp. 187-190
-
-
Hesse, C.1
Rosengren, L.2
Andreasen, N.3
Davidsson, P.4
Vanderstichele, H.5
Vanmechelen, E.6
Blennow, K.7
-
37
-
-
4544248870
-
Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease
-
Horowitz, P.M., Patterson, K.R., Guillozet-Bongaarts, A.L., Reynolds, M.R., Carroll, C.A., Weintraub, S.T., Bennett, D.A., Cryns, V.L., Berry, R.W., Binder, L.I., Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease. J. Neurosci. 24 (2004), 7895–7902.
-
(2004)
J. Neurosci.
, vol.24
, pp. 7895-7902
-
-
Horowitz, P.M.1
Patterson, K.R.2
Guillozet-Bongaarts, A.L.3
Reynolds, M.R.4
Carroll, C.A.5
Weintraub, S.T.6
Bennett, D.A.7
Cryns, V.L.8
Berry, R.W.9
Binder, L.I.10
-
38
-
-
33750380827
-
N-terminal fragments of tau inhibit full-length tau polymerization in vitro
-
Horowitz, P.M., LaPointe, N., Guillozet-Bongaarts, A.L., Berry, R.W., Binder, L.I., N-terminal fragments of tau inhibit full-length tau polymerization in vitro. Biochemistry 45 (2006), 12859–12866.
-
(2006)
Biochemistry
, vol.45
, pp. 12859-12866
-
-
Horowitz, P.M.1
LaPointe, N.2
Guillozet-Bongaarts, A.L.3
Berry, R.W.4
Binder, L.I.5
-
39
-
-
84872346089
-
Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy
-
Iba, M., Guo, J.L., McBride, J.D., Zhang, B., Trojanowski, J.Q., Lee, V.M.-Y., Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy. J. Neurosci. 33 (2013), 1024–1037.
-
(2013)
J. Neurosci.
, vol.33
, pp. 1024-1037
-
-
Iba, M.1
Guo, J.L.2
McBride, J.D.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.-Y.6
-
40
-
-
84938490181
-
C-terminally truncated forms of Tau, but not full-length Tau or its C-terminal fragments, are released from neurons independently of cell death
-
Kanmert, D., Cantlon, A., Muratore, C.R., Jin, M., O'Malley, T.T., Lee, G., Young-Pearse, T.L., Selkoe, D.J., Walsh, D.M., C-terminally truncated forms of Tau, but not full-length Tau or its C-terminal fragments, are released from neurons independently of cell death. J. Neurosci. 35 (2015), 10851–10865.
-
(2015)
J. Neurosci.
, vol.35
, pp. 10851-10865
-
-
Kanmert, D.1
Cantlon, A.2
Muratore, C.R.3
Jin, M.4
O'Malley, T.T.5
Lee, G.6
Young-Pearse, T.L.7
Selkoe, D.J.8
Walsh, D.M.9
-
41
-
-
84871141635
-
Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies
-
Karch, C.M., Jeng, A.T., Goate, A.M., Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies. J. Biol. Chem. 287 (2012), 42751–42762.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 42751-42762
-
-
Karch, C.M.1
Jeng, A.T.2
Goate, A.M.3
-
42
-
-
84861758226
-
Trans-cellular propagation of Tau aggregation by fibrillar species
-
Kfoury, N., Holmes, B.B., Jiang, H., Holtzman, D.M., Diamond, M.I., Trans-cellular propagation of Tau aggregation by fibrillar species. J. Biol. Chem. 287 (2012), 19440–19451.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 19440-19451
-
-
Kfoury, N.1
Holmes, B.B.2
Jiang, H.3
Holtzman, D.M.4
Diamond, M.I.5
-
43
-
-
0027534625
-
Application of synthetic phospho- and unphospho- peptides to identify phosphorylation sites in a subregion of the tau molecule, which is modified in Alzheimer's disease
-
Liu, W.-K., Moore, W.T., Williams, R.T., Hall, F.L., Yen, S.-H., Application of synthetic phospho- and unphospho- peptides to identify phosphorylation sites in a subregion of the tau molecule, which is modified in Alzheimer's disease. J. Neurosci. Res. 34 (1993), 371–376.
-
(1993)
J. Neurosci. Res.
, vol.34
, pp. 371-376
-
-
Liu, W.-K.1
Moore, W.T.2
Williams, R.T.3
Hall, F.L.4
Yen, S.-H.5
-
44
-
-
84856454190
-
Trans-synaptic spread of tau pathology in vivo
-
Liu, L., Drouet, V., Wu, J.W., Witter, M.P., Small, S.A., Clelland, C., Duff, K., Trans-synaptic spread of tau pathology in vivo. PLoS ONE, 7, 2012, e31302.
-
(2012)
PLoS ONE
, vol.7
, pp. e31302
-
-
Liu, L.1
Drouet, V.2
Wu, J.W.3
Witter, M.P.4
Small, S.A.5
Clelland, C.6
Duff, K.7
-
45
-
-
84964575878
-
Co-immunoprecipitation with Tau isoform-specific antibodies reveals distinct protein interactions and highlights a putative role for 2N Tau in disease
-
Liu, C., Song, X., Nisbet, R., Götz, J., Co-immunoprecipitation with Tau isoform-specific antibodies reveals distinct protein interactions and highlights a putative role for 2N Tau in disease. J. Biol. Chem. 291 (2016), 8173–8188.
-
(2016)
J. Biol. Chem.
, vol.291
, pp. 8173-8188
-
-
Liu, C.1
Song, X.2
Nisbet, R.3
Götz, J.4
-
46
-
-
84930966153
-
Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody
-
Luo, W., Liu, W., Hu, X., Hanna, M., Caravaca, A., Paul, S.M., Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody. Sci. Rep., 5, 2015, 11161.
-
(2015)
Sci. Rep.
, vol.5
, pp. 11161
-
-
Luo, W.1
Liu, W.2
Hu, X.3
Hanna, M.4
Caravaca, A.5
Paul, S.M.6
-
47
-
-
84963805081
-
FLEXITau: quantifying post-translational modifications of Tau protein in vitro and in human disease
-
Mair, W., Muntel, J., Tepper, K., Tang, S., Biernat, J., Seeley, W.W., Kosik, K.S., Mandelkow, E., Steen, H., Steen, J.A., FLEXITau: quantifying post-translational modifications of Tau protein in vitro and in human disease. Anal. Chem. 88 (2016), 3704–3714.
-
(2016)
Anal. Chem.
, vol.88
, pp. 3704-3714
-
-
Mair, W.1
Muntel, J.2
Tepper, K.3
Tang, S.4
Biernat, J.5
Seeley, W.W.6
Kosik, K.S.7
Mandelkow, E.8
Steen, H.9
Steen, J.A.10
-
48
-
-
0345276565
-
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
-
Mandelkow, E.-M., Stamer, K., Vogel, R., Thies, E., Mandelkow, E., Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses. Neurobiol. Aging 24 (2003), 1079–1085.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 1079-1085
-
-
Mandelkow, E.-M.1
Stamer, K.2
Vogel, R.3
Thies, E.4
Mandelkow, E.5
-
49
-
-
84897522070
-
Quantification of tau in cerebrospinal fluid by immunoaffinity enrichment and tandem mass spectrometry
-
McAvoy, T., Lassman, M.E., Spellman, D.S., Ke, Z., Howell, B.J., Wong, O., Zhu, L., Tanen, M., Struyk, A., Laterza, O.F., Quantification of tau in cerebrospinal fluid by immunoaffinity enrichment and tandem mass spectrometry. Clin. Chem. 60 (2014), 683–689.
-
(2014)
Clin. Chem.
, vol.60
, pp. 683-689
-
-
McAvoy, T.1
Lassman, M.E.2
Spellman, D.S.3
Ke, Z.4
Howell, B.J.5
Wong, O.6
Zhu, L.7
Tanen, M.8
Struyk, A.9
Laterza, O.F.10
-
50
-
-
84885041658
-
Characterization of novel CSF Tau and ptau biomarkers for Alzheimer's disease
-
Meredith, J.E. Jr., Sankaranarayanan, S., Guss, V., Lanzetti, A.J., Berisha, F., Neely, R.J., Slemmon, J.R., Portelius, E., Zetterberg, H., Blennow, K., et al. Characterization of novel CSF Tau and ptau biomarkers for Alzheimer's disease. PLoS ONE, 8, 2013, e76523.
-
(2013)
PLoS ONE
, vol.8
, pp. e76523
-
-
Meredith, J.E.1
Sankaranarayanan, S.2
Guss, V.3
Lanzetti, A.J.4
Berisha, F.5
Neely, R.J.6
Slemmon, J.R.7
Portelius, E.8
Zetterberg, H.9
Blennow, K.10
-
51
-
-
85027832439
-
AV-1451 PET imaging of tau pathology in preclinical Alzheimer disease: Defining a summary measure
-
Mishra, S., Gordon, B.A., Su, Y., Christensen, J., Friedrichsen, K., Jackson, K., Hornbeck, R., Balota, D.A., Cairns, N.J., Morris, J.C., et al. AV-1451 PET imaging of tau pathology in preclinical Alzheimer disease: Defining a summary measure. Neuroimage 161 (2017), 171–178.
-
(2017)
Neuroimage
, vol.161
, pp. 171-178
-
-
Mishra, S.1
Gordon, B.A.2
Su, Y.3
Christensen, J.4
Friedrichsen, K.5
Jackson, K.6
Hornbeck, R.7
Balota, D.A.8
Cairns, N.J.9
Morris, J.C.10
-
52
-
-
70350455151
-
Specification of neuronal polarity regulated by local translation of CRMP2 and Tau via the mTOR-p70S6K pathway
-
Morita, T., Sobue, K., Specification of neuronal polarity regulated by local translation of CRMP2 and Tau via the mTOR-p70S6K pathway. J. Biol. Chem. 284 (2009), 27734–27745.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 27734-27745
-
-
Morita, T.1
Sobue, K.2
-
53
-
-
0023505501
-
Phosphorylation determines two distinct species of Tau in the central nervous system
-
Papasozomenos, S.C., Binder, L.I., Phosphorylation determines two distinct species of Tau in the central nervous system. Cell Motil. Cytoskeleton 8 (1987), 210–226.
-
(1987)
Cell Motil. Cytoskeleton
, vol.8
, pp. 210-226
-
-
Papasozomenos, S.C.1
Binder, L.I.2
-
54
-
-
84939653898
-
Age and amyloid effects on human central nervous system amyloid-beta kinetics
-
Patterson, B.W., Elbert, D.L., Mawuenyega, K.G., Kasten, T., Ovod, V., Ma, S., Xiong, C., Chott, R., Yarasheski, K., Sigurdson, W., et al. Age and amyloid effects on human central nervous system amyloid-beta kinetics. Ann. Neurol. 78 (2015), 439–453.
-
(2015)
Ann. Neurol.
, vol.78
, pp. 439-453
-
-
Patterson, B.W.1
Elbert, D.L.2
Mawuenyega, K.G.3
Kasten, T.4
Ovod, V.5
Ma, S.6
Xiong, C.7
Chott, R.8
Yarasheski, K.9
Sigurdson, W.10
-
55
-
-
84876459364
-
Physiological release of endogenous tau is stimulated by neuronal activity
-
Pooler, A.M., Phillips, E.C., Lau, D.H.W., Noble, W., Hanger, D.P., Physiological release of endogenous tau is stimulated by neuronal activity. EMBO Rep. 14 (2013), 389–394.
-
(2013)
EMBO Rep.
, vol.14
, pp. 389-394
-
-
Pooler, A.M.1
Phillips, E.C.2
Lau, D.H.W.3
Noble, W.4
Hanger, D.P.5
-
56
-
-
84886509822
-
A role for tau at the synapse in Alzheimer's disease pathogenesis
-
Pooler, A.M., Noble, W., Hanger, D.P., A role for tau at the synapse in Alzheimer's disease pathogenesis. Neuropharmacology 76:Pt A (2014), 1–8.
-
(2014)
Neuropharmacology
, vol.76
, pp. 1-8
-
-
Pooler, A.M.1
Noble, W.2
Hanger, D.P.3
-
57
-
-
52049096219
-
Characterization of tau in cerebrospinal fluid using mass spectrometry
-
Portelius, E., Hansson, S.F., Tran, A.J., Zetterberg, H., Grognet, P., Vanmechelen, E., Höglund, K., Brinkmalm, G., Westman-Brinkmalm, A., Nordhoff, E., et al. Characterization of tau in cerebrospinal fluid using mass spectrometry. J. Proteome Res. 7 (2008), 2114–2120.
-
(2008)
J. Proteome Res.
, vol.7
, pp. 2114-2120
-
-
Portelius, E.1
Hansson, S.F.2
Tran, A.J.3
Zetterberg, H.4
Grognet, P.5
Vanmechelen, E.6
Höglund, K.7
Brinkmalm, G.8
Westman-Brinkmalm, A.9
Nordhoff, E.10
-
58
-
-
84880525521
-
Increased in vivo amyloid-β42 production, exchange, and loss in presenilin mutation carriers
-
Potter, R., Patterson, B.W., Elbert, D.L., Ovod, V., Kasten, T., Sigurdson, W., Mawuenyega, K., Blazey, T., Goate, A., Chott, R., et al. Increased in vivo amyloid-β42 production, exchange, and loss in presenilin mutation carriers. Sci. Transl. Med., 5, 2013, 189ra77.
-
(2013)
Sci. Transl. Med.
, vol.5
, pp. 189ra77
-
-
Potter, R.1
Patterson, B.W.2
Elbert, D.L.3
Ovod, V.4
Kasten, T.5
Sigurdson, W.6
Mawuenyega, K.7
Blazey, T.8
Goate, A.9
Chott, R.10
-
59
-
-
77956271728
-
Analysis of proteome dynamics in the mouse brain
-
Price, J.C., Guan, S., Burlingame, A., Prusiner, S.B., Ghaemmaghami, S., Analysis of proteome dynamics in the mouse brain. Proc. Natl. Acad. Sci. USA 107 (2010), 14508–14513.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 14508-14513
-
-
Price, J.C.1
Guan, S.2
Burlingame, A.3
Prusiner, S.B.4
Ghaemmaghami, S.5
-
60
-
-
0031955835
-
Correction for partial volume effects in PET: principle and validation
-
Rousset, O.G., Ma, Y., Evans, A.C., Correction for partial volume effects in PET: principle and validation. J. Nucl. Med. 39 (1998), 904–911.
-
(1998)
J. Nucl. Med.
, vol.39
, pp. 904-911
-
-
Rousset, O.G.1
Ma, Y.2
Evans, A.C.3
-
61
-
-
84902486430
-
Distinct tau prion strains propagate in cells and mice and define different tauopathies
-
Sanders, D.W., Kaufman, S.K., DeVos, S.L., Sharma, A.M., Mirbaha, H., Li, A., Barker, S.J., Foley, A.C., Thorpe, J.R., Serpell, L.C., et al. Distinct tau prion strains propagate in cells and mice and define different tauopathies. Neuron 82 (2014), 1271–1288.
-
(2014)
Neuron
, vol.82
, pp. 1271-1288
-
-
Sanders, D.W.1
Kaufman, S.K.2
DeVos, S.L.3
Sharma, A.M.4
Mirbaha, H.5
Li, A.6
Barker, S.J.7
Foley, A.C.8
Thorpe, J.R.9
Serpell, L.C.10
-
62
-
-
84990061214
-
Human iPSC-derived neuronal model of Tau-A152T frontotemporal dementia reveals Tau-mediated mechanisms of neuronal vulnerability
-
Silva, M.C., Cheng, C., Mair, W., Almeida, S., Fong, H., Biswas, M.H.U., Zhang, Z., Huang, Y., Temple, S., Coppola, G., et al. Human iPSC-derived neuronal model of Tau-A152T frontotemporal dementia reveals Tau-mediated mechanisms of neuronal vulnerability. Stem Cell Reports 7 (2016), 325–340.
-
(2016)
Stem Cell Reports
, vol.7
, pp. 325-340
-
-
Silva, M.C.1
Cheng, C.2
Mair, W.3
Almeida, S.4
Fong, H.5
Biswas, M.H.U.6
Zhang, Z.7
Huang, Y.8
Temple, S.9
Coppola, G.10
-
63
-
-
0034741554
-
Tau and Abeta42 in cerebrospinal fluid from healthy adults 21-93 years of age: establishment of reference values
-
Sjögren, M., Vanderstichele, H., Ågren, H., Zachrisson, O., Edsbagge, M., Wikkelsø C., Skoog, I., Wallin, A., Wahlund, L.-O., Marcusson, J., et al. Tau and Abeta42 in cerebrospinal fluid from healthy adults 21-93 years of age: establishment of reference values. Clin. Chem. 47 (2001), 1776–1781.
-
(2001)
Clin. Chem.
, vol.47
, pp. 1776-1781
-
-
Sjögren, M.1
Vanderstichele, H.2
Ågren, H.3
Zachrisson, O.4
Edsbagge, M.5
Wikkelsø, C.6
Skoog, I.7
Wallin, A.8
Wahlund, L.-O.9
Marcusson, J.10
-
64
-
-
84940664560
-
Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT
-
Sposito, T., Preza, E., Mahoney, C.J., Setó-Salvia, N., Ryan, N.S., Morris, H.R., Arber, C., Devine, M.J., Houlden, H., Warner, T.T., et al. Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT. Hum. Mol. Genet. 24 (2015), 5260–5269.
-
(2015)
Hum. Mol. Genet.
, vol.24
, pp. 5260-5269
-
-
Sposito, T.1
Preza, E.2
Mahoney, C.J.3
Setó-Salvia, N.4
Ryan, N.S.5
Morris, H.R.6
Arber, C.7
Devine, M.J.8
Houlden, H.9
Warner, T.T.10
-
65
-
-
10944227282
-
Tau phosphorylation: physiological and pathological consequences
-
Stoothoff, W.H., Johnson, G.V.W., Tau phosphorylation: physiological and pathological consequences. Biochim. Biophys. Acta 1739 (2005), 280–297.
-
(2005)
Biochim. Biophys. Acta
, vol.1739
, pp. 280-297
-
-
Stoothoff, W.H.1
Johnson, G.V.W.2
-
66
-
-
84892402771
-
Quantitative analysis of PiB-PET with FreeSurfer ROIs
-
Su, Y., D'Angelo, G.M., Vlassenko, A.G., Zhou, G., Snyder, A.Z., Marcus, D.S., Blazey, T.M., Christensen, J.J., Vora, S., Morris, J.C., et al. Quantitative analysis of PiB-PET with FreeSurfer ROIs. PLoS ONE, 8, 2013, e73377.
-
(2013)
PLoS ONE
, vol.8
, pp. e73377
-
-
Su, Y.1
D'Angelo, G.M.2
Vlassenko, A.G.3
Zhou, G.4
Snyder, A.Z.5
Marcus, D.S.6
Blazey, T.M.7
Christensen, J.J.8
Vora, S.9
Morris, J.C.10
-
67
-
-
84917726968
-
Partial volume correction in quantitative amyloid imaging
-
Su, Y., Blazey, T.M., Snyder, A.Z., Raichle, M.E., Marcus, D.S., Ances, B.M., Bateman, R.J., Cairns, N.J., Aldea, P., Cash, L., et al., Dominantly Inherited Alzheimer Network. Partial volume correction in quantitative amyloid imaging. Neuroimage 107 (2015), 55–64.
-
(2015)
Neuroimage
, vol.107
, pp. 55-64
-
-
Su, Y.1
Blazey, T.M.2
Snyder, A.Z.3
Raichle, M.E.4
Marcus, D.S.5
Ances, B.M.6
Bateman, R.J.7
Cairns, N.J.8
Aldea, P.9
Cash, L.10
-
68
-
-
67649622427
-
Pseudohyperphosphorylation causing AD-like changes in tau has significant effects on its polymerization
-
Sun, Q., Gamblin, T.C., Pseudohyperphosphorylation causing AD-like changes in tau has significant effects on its polymerization. Biochemistry 48 (2009), 6002–6011.
-
(2009)
Biochemistry
, vol.48
, pp. 6002-6011
-
-
Sun, Q.1
Gamblin, T.C.2
-
69
-
-
0027388775
-
Recognition of the minimal epitope of monoclonal antibody Tau-1 depends upon the presence of a phosphate group but not its location
-
Szendrei, G.I., Lee, V.M.-Y., Otvos, L. Jr., Recognition of the minimal epitope of monoclonal antibody Tau-1 depends upon the presence of a phosphate group but not its location. J. Neurosci. Res. 34 (1993), 243–249.
-
(1993)
J. Neurosci. Res.
, vol.34
, pp. 243-249
-
-
Szendrei, G.I.1
Lee, V.M.-Y.2
Otvos, L.3
-
70
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi, K., Yamanaka, S., Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126 (2006), 663–676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
71
-
-
84888201046
-
Longitudinal change in CSF Tau and Aβ biomarkers for up to 48 months in ADNI
-
Toledo, J.B., Xie, S.X., Trojanowski, J.Q., Shaw, L.M., Longitudinal change in CSF Tau and Aβ biomarkers for up to 48 months in ADNI. Acta Neuropathol. 126 (2013), 659–670.
-
(2013)
Acta Neuropathol.
, vol.126
, pp. 659-670
-
-
Toledo, J.B.1
Xie, S.X.2
Trojanowski, J.Q.3
Shaw, L.M.4
-
72
-
-
84865791125
-
MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies
-
Trabzuni, D., Wray, S., Vandrovcova, J., Ramasamy, A., Walker, R., Smith, C., Luk, C., Gibbs, J.R., Dillman, A., Hernandez, D.G., et al. MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies. Hum. Mol. Genet. 21 (2012), 4094–4103.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 4094-4103
-
-
Trabzuni, D.1
Wray, S.2
Vandrovcova, J.3
Ramasamy, A.4
Walker, R.5
Smith, C.6
Luk, C.7
Gibbs, J.R.8
Dillman, A.9
Hernandez, D.G.10
-
73
-
-
84951567833
-
Tau in physiology and pathology
-
Wang, Y., Mandelkow, E., Tau in physiology and pathology. Nat. Rev. Neurosci. 17 (2016), 5–21.
-
(2016)
Nat. Rev. Neurosci.
, vol.17
, pp. 5-21
-
-
Wang, Y.1
Mandelkow, E.2
-
74
-
-
84975222113
-
Neuronal activity enhances tau propagation and tau pathology in vivo
-
Wu, J.W., Hussaini, S.A., Bastille, I.M., Rodriguez, G.A., Mrejeru, A., Rilett, K., Sanders, D.W., Cook, C., Fu, H., Boonen, R.A.C.M., et al. Neuronal activity enhances tau propagation and tau pathology in vivo. Nat. Neurosci. 19 (2016), 1085–1092.
-
(2016)
Nat. Neurosci.
, vol.19
, pp. 1085-1092
-
-
Wu, J.W.1
Hussaini, S.A.2
Bastille, I.M.3
Rodriguez, G.A.4
Mrejeru, A.5
Rilett, K.6
Sanders, D.W.7
Cook, C.8
Fu, H.9
Boonen, R.A.C.M.10
-
75
-
-
80052940324
-
In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice
-
Yamada, K., Cirrito, J.R., Stewart, F.R., Jiang, H., Finn, M.B., Holmes, B.B., Binder, L.I., Mandelkow, E.-M., Diamond, M.I., Lee, V.M.-Y., Holtzman, D.M., In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice. J. Neurosci. 31 (2011), 13110–13117.
-
(2011)
J. Neurosci.
, vol.31
, pp. 13110-13117
-
-
Yamada, K.1
Cirrito, J.R.2
Stewart, F.R.3
Jiang, H.4
Finn, M.B.5
Holmes, B.B.6
Binder, L.I.7
Mandelkow, E.-M.8
Diamond, M.I.9
Lee, V.M.-Y.10
Holtzman, D.M.11
-
76
-
-
84896830709
-
Neuronal activity regulates extracellular tau in vivo
-
Yamada, K., Holth, J.K., Liao, F., Stewart, F.R., Mahan, T.E., Jiang, H., Cirrito, J.R., Patel, T.K., Hochgräfe, K., Mandelkow, E.-M., Holtzman, D.M., Neuronal activity regulates extracellular tau in vivo. J. Exp. Med. 211 (2014), 387–393.
-
(2014)
J. Exp. Med.
, vol.211
, pp. 387-393
-
-
Yamada, K.1
Holth, J.K.2
Liao, F.3
Stewart, F.R.4
Mahan, T.E.5
Jiang, H.6
Cirrito, J.R.7
Patel, T.K.8
Hochgräfe, K.9
Mandelkow, E.-M.10
Holtzman, D.M.11
-
77
-
-
84945293479
-
Analysis of in vivo turnover of tau in a mouse model of tauopathy
-
Yamada, K., Patel, T.K., Hochgräfe, K., Mahan, T.E., Jiang, H., Stewart, F.R., Mandelkow, E.-M., Holtzman, D.M., Analysis of in vivo turnover of tau in a mouse model of tauopathy. Mol. Neurodegener., 10, 2015, 55.
-
(2015)
Mol. Neurodegener.
, vol.10
, pp. 55
-
-
Yamada, K.1
Patel, T.K.2
Hochgräfe, K.3
Mahan, T.E.4
Jiang, H.5
Stewart, F.R.6
Mandelkow, E.-M.7
Holtzman, D.M.8
-
78
-
-
84885783467
-
Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo
-
Yanamandra, K., Kfoury, N., Jiang, H., Mahan, T.E., Ma, S., Maloney, S.E., Wozniak, D.F., Diamond, M.I., Holtzman, D.M., Anti-tau antibodies that block tau aggregate seeding in vitro markedly decrease pathology and improve cognition in vivo. Neuron 80 (2013), 402–414.
-
(2013)
Neuron
, vol.80
, pp. 402-414
-
-
Yanamandra, K.1
Kfoury, N.2
Jiang, H.3
Mahan, T.E.4
Ma, S.5
Maloney, S.E.6
Wozniak, D.F.7
Diamond, M.I.8
Holtzman, D.M.9
-
79
-
-
85014531490
-
Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia
-
Yokoyama, J.S., Karch, C.M., Fan, C.C., Bonham, L.W., Kouri, N., Ross, O.A., Rademakers, R., Kim, J., Wang, Y., Höglinger, G.U., et al., International FTD-Genomics Consortium (IFGC). Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia. Acta Neuropathol. 133 (2017), 825–837.
-
(2017)
Acta Neuropathol.
, vol.133
, pp. 825-837
-
-
Yokoyama, J.S.1
Karch, C.M.2
Fan, C.C.3
Bonham, L.W.4
Kouri, N.5
Ross, O.A.6
Rademakers, R.7
Kim, J.8
Wang, Y.9
Höglinger, G.U.10
-
80
-
-
85025167025
-
Axodendritic sorting and pathological missorting of Tau are isoform-specific and determined by axon initial segment architecture
-
Zempel, H., Dennissen, F.J.A., Kumar, Y., Luedtke, J., Biernat, J., Mandelkow, E.-M., Mandelkow, E., Axodendritic sorting and pathological missorting of Tau are isoform-specific and determined by axon initial segment architecture. J. Biol. Chem. 292 (2017), 12192–12207.
-
(2017)
J. Biol. Chem.
, vol.292
, pp. 12192-12207
-
-
Zempel, H.1
Dennissen, F.J.A.2
Kumar, Y.3
Luedtke, J.4
Biernat, J.5
Mandelkow, E.-M.6
Mandelkow, E.7
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