Genome-wide CRISPR-dCas9 screens in E. coli identify essential genes and phage host factors

PLoS Genetics

Volumn 14, Issue 11, 2018, Pages

  Rousset, François ^a,b   Cui, Lun ^a   Siouve, Elise ^a,d   Becavin, Christophe ^c   Depardieu, Florence ^a   Bikard, David ^a  

^a INSTITUT PASTEUR   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c CNRS   (France)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL CHROMOSOME; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIOPHAGE; CONTROLLED STUDY; CRISPR-CAS9 SYSTEM; ESCHERICHIA COLI; GENE EXPRESSION; GENE IDENTIFICATION; GENE REPRESSION; GENE TARGETING; GENETIC SCREENING; GENOME-WIDE ASSOCIATION STUDY; NONHUMAN; SYNTHESIS; VIRUS CAPSID; BACTERIAL GENOME; CRISPR CAS SYSTEM; ESSENTIAL GENE; GENETIC ASSOCIATION STUDY; GENETICS; HOST PATHOGEN INTERACTION; VIROLOGY;

CRISPR-CAS SYSTEMS; ESCHERICHIA COLI; GENES, ESSENTIAL; GENETIC ASSOCIATION STUDIES; GENOME, BACTERIAL; GENOME-WIDE ASSOCIATION STUDY; HOST-PATHOGEN INTERACTIONS;

EID: 85056707092     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1007749     Document Type: Article

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