A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors

Nature Genetics

Volumn 49, Issue 2, 2017, Pages 193-203

  Park, Ryan J ^a,b,c   Wang, Tim ^c,d,e   Koundakjian, Dylan ^a   Hultquist, Judd F ^f,g   Lamothe Molina, Pedro ^a,h   Monel, Blandine ^a,i   Schumann, Kathrin ^j   Yu, Haiyan ^c   Krupzcak, Kevin M ^e   Garcia Beltran, Wilfredo ^a,b   Piechocka Trocha, Alicja ^a   Krogan, Nevan J ^f,g   Marson, Alexander ^f,j,k,l   Sabatini, David M ^c,d,e   Lander, Eric S ^b,c,d   Hacohen, Nir ^c,m   Walker, Bruce D ^a,c,i,n  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g GLADSTONE INSTITUTE OF VIROLOGY AND IMMUNOLOGY   (United States)

^h HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

ⁱ MASSACHUSETTS GENERAL HOSPITAL   (United States)

^j UNIVERSITY OF CALIFORNIA   (United States)

^k UNIVERSITY OF CALIFORNIA   (United States)

^l UNIVERSITY OF CALIFORNIA   (United States)

^m MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

ⁿ Massachusetts Institute of Technology Cambridge   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE; ANTIBODY; CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; DECAY ACCELERATING FACTOR; HOST FACTOR; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; SOLUTE FAMILY 35 MEMBER B2; TYROSINE; TYROSYLPROTEIN SULFOTRANSFERASE 2; UNCLASSIFIED DRUG; CCR5 PROTEIN, HUMAN; MEMBRANE PROTEIN; SULFOTRANSFERASE; TPST2 PROTEIN, HUMAN;

ARTICLE; CD4+ T LYMPHOCYTE; CELL AGGREGATION; CELL PROLIFERATION; CELL VIABILITY; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; FLOW CYTOMETRY; GENE EDITING; GENOME-WIDE ASSOCIATION STUDY; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SULFATION; VIRUS CELL INTERACTION; VIRUS ENTRY; VIRUS ENVELOPE; VIRUS REPLICATION; VIRUS TRANSMISSION; CELL LINE; GENETICS; GENOME; HOST PATHOGEN INTERACTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; PATHOGENICITY; PHYSIOLOGY; RNA INTERFERENCE;

ACTIVATED-LEUKOCYTE CELL ADHESION MOLECULE; CELL LINE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; GENOME; HIV INFECTIONS; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; MEMBRANE PROTEINS; RECEPTORS, CCR5; RNA INTERFERENCE; SULFOTRANSFERASES; VIRUS REPLICATION;

EID: 85006469855     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3741     Document Type: Article

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