Molecular basis for chloronium-mediated meroterpene cyclization: Cloning, sequencing, and heterologous expression of the napyradiomycin biosynthetic gene cluster

Journal of Biological Chemistry

Volumn 282, Issue 22, 2007, Pages 16362-16368

  Winter, Jaclyn M ^a   Moffitt, Michelle C ^a   Zazopoulos, Emmanuel ^b   McAlpine, James B ^b   Dorrestein, Pieter C ^c   Moore, Bradley S ^a,c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b Ecopia Biosciences Inc   (Canada)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; BACTERIA; BIOSYNTHESIS; CATALYST ACTIVITY; FUNGI; GENE EXPRESSION;

BIOSYNTHETIC CYCLIZATION; MEROTERPENE CYCLIZATION;

GENETIC ENGINEERING;

TERPENE DERIVATIVE; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; NAPHTHOQUINONE; PEROXIDASE; TERPENE; VANADIUM;

ARTICLE; CYCLIZATION; GENE CLUSTER; GENE SEQUENCE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STREPTOMYCES; STREPTOMYCES ACULEOLATUS; BIOSYNTHESIS; CATALYSIS; DNA SEQUENCE; ENZYMOLOGY; GENE EXPRESSION; GENETICS; METABOLISM; MOLECULAR GENETICS; MULTIGENE FAMILY; OPEN READING FRAME; PHYSIOLOGY;

ALGAE; BACTERIA (MICROORGANISMS); FUNGI; STREPTOMYCES ACULEOLATUS; STREPTOMYCES ALBUS; STREPTOMYCES SP.;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BASE SEQUENCE; CATALYSIS; CLONING, MOLECULAR; GENE EXPRESSION; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; NAPHTHOQUINONES; OPEN READING FRAMES; PEROXIDASES; SEQUENCE ANALYSIS, DNA; STREPTOMYCES; TERPENES; VANADIUM;

EID: 34447558011     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M611046200     Document Type: Article

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