Metabolic engineering of Escherichia coli for the enhanced production of l-tyrosine

Biotechnology and Bioengineering

Volumn 115, Issue 10, 2018, Pages 2554-2564

  Kim, Byoungjin ^a   Binkley, Robert ^a   Kim, Hyun Uk ^a   Lee, Sang Yup ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Escherichia coli; fed batch fermentation; l tyrosine; metabolic engineering

Indexed keywords

ESCHERICHIA COLI; FEEDING; FERMENTATION; GENES; METABOLIC ENGINEERING; METABOLISM;

BIOSYNTHETIC PATHWAY; CHORISMATE MUTASE; EXPONENTIAL FEEDING; FED-BATCH FERMENTATION; L-TYROSINE; PRODUCTION PERFORMANCE; STRAIN DEVELOPMENT; ZYMOMONAS MOBILIS;

AMINO ACIDS;

CHORISMATE MUTASE; GENOMIC DNA; PREPHENATE DEHYDROGENASE; TYROSINE; ESCHERICHIA COLI PROTEIN;

ARTICLE; BACTERIAL STRAIN; BIOSYNTHESIS; ESCHERICHIA COLI; FED BATCH FERMENTATION; GENE CONTROL; GENE OVEREXPRESSION; METABOLIC ENGINEERING; NONHUMAN; ZYMOMONAS MOBILIS; GENETICS; METABOLISM;

BIOSYNTHETIC PATHWAYS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; METABOLIC ENGINEERING; TYROSINE;

EID: 85052688100     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.26797     Document Type: Article

References (42)

1. Andrews, A. E., Lawley, B., & Pittard, A. J. (1991). Mutational analysis of repression and activation of the tyrP gene in Escherichia coli. Journal of Bacteriology, 173, 5068–5078
2. Brown, K. D. (1970). Formation of aromatic amino acid pools in Escherichia coli K-12. Journal of Bacteriology, 104, 177–188
3. Chávez-Béjar, M. I., Báez-Viveros, J. L., Martínez, A., Bolívar, F., & Gosset, G. (2012). Biotechnological production of l-tyrosine and derived compounds. Process Biochemistry, 47, 1017–1026
4. Chávez-Béjar, M. I., Lara, A. R., Lopez, H., Hernandez-Chavez, G., Martinez, A., Ramirez, O. T., … Gosset, G. (2008). Metabolic engineering of Escherichia coli for l-tyrosine production by expression of genes coding for the chorismate mutase domain of the native chorismate mutase-prephenate dehydratase and a cyclohexadienyl dehydrogenase from Zymomonas mobilis. Applied and Environmental Microbiology, 74, 3284–3290
5. Cosgriff, A. J., & Pittard, A. J. (1997). A topological model for the general aromatic amino acid permease, AroP, of Escherichia coli. Journal of Bacteriology, 179, 3317–3323
6. Datsenko, K. A., & Wanner, B. L. (2000). One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proceedings of the National Academy of Sciences of the United States of America, 97, 6640–6645
7. DeFeyter, R. C., & Pittard, J. (1986). Purification and properties of shikimate kinase II from Escherichia coli K-12. Journal of Bacteriology, 165, 331–333
8. Dell, K. A., & Frost, J. W. (1993). Identification and removal of impediments to biocatalytic synthesis of aromatics from d-glucose: Rate-limiting enzymes in the common pathway of aromatic amino acid biosynthesis. Journal of the American Chemical Society, 115, 11581–11589
9. Ely, B., & Pittard, J. (1979). Aromatic amino acid biosynthesis: Regulation of shikimate kinase in Escherichia coli K-12. Journal of Bacteriology, 138, 933–943
10. Fischer, R., Vasilev, N., Twyman, R. M., & Schillberg, S. (2015). High-value products from plants: The challenges of process optimization. Current Opinion in Biotechnology, 32, 156–162
11. Gibson, D. G., Smith, H. O., Hutchison, C. A., 3rd, Venter, J. C., & Merryman, C. (2010). Chemical synthesis of the mouse mitochondrial genome. Nature Methods, 7, 901–903
12. Gibson, D. G., Young, L., Chuang, R. Y., Venter, J. C., Hutchison, C. A., 3rd, & Smith, H. O. (2009). Enzymatic assembly of DNA molecules up to several hundred kilobases. Nature Methods, 6, 343–345
13. Jones, K. L., Kim, S. W., & Keasling, J. D. (2000). Low-copy plasmids can perform as well as or better than high-copy plasmids for metabolic engineering of bacteria. Metabolic Engineering, 2, 328–338
14. Juminaga, D., Baidoo, E. E. K., Redding-Johanson, A. M., Batth, T. S., Burd, H., Mukhopadhyay, A., … Keasling, J. D. (2012). Modular engineering of l-tyrosine production in Escherichia coli. Applied and Environmental Microbiology, 78, 89–98
15. Katsuyama, Y., Funa, N., Miyahisa, I., & Horinouchi, S. (2007). Synthesis of unnatural flavonoids and stilbenes by exploiting the plant biosynthetic pathway in Escherichia coli. Chemistry and Biology, 14, 613–621
16. Kikuchi, Y., Tsujimoto, K., & Kurahashi, O. (1997). Mutational analysis of the feedback sites of phenylalanine-sensitive 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase of Escherichia coli. Applied and Environmental Microbiology, 63, 761–762
17. Lee, J. W., Na, D., Park, J. M., Lee, J., Choi, S., & Lee, S. Y. (2012). Systems metabolic engineering of microorganisms for natural and non-natural chemicals. Nature Chemical Biology, 8, 536–546
18. Lee, S. Y. (1996). High cell-density culture of Escherichia coli. Trends in Biotechnology, 14, 98–105
19. Lee, S. Y., & Kim, H. U. (2015). Systems strategies for developing industrial microbial strains. Nature Biotechnology, 33, 1061–1072
20. Lim, C. G., Fowler, Z. L., Hueller, T., Schaffer, S., & Koffas, M. A. G. (2011). High-yield resveratrol production in engineered Escherichia coli. Applied and Environmental Microbiology, 77, 3451–3460
21. Løbner-Olesen, A., & Marinus, M. G. (1992). Identification of the gene (aroK) encoding shikimic acid kinase I of Escherichia coli. Journal of Bacteriology, 174, 525–529
22. Luo, Z. W., & Lee, S. Y. (2017). Biotransformation of p-xylene into terephthalic acid by engineered Escherichia coli. Nature Communications, 8, 15689
23. Lütke-Eversloh, T., Santos, C. N. S., & Stephanopoulos, G. (2007). Perspectives of biotechnological production of l-tyrosine and its applications. Applied Microbiology and Biotechnology, 77, 751–762
24. Lütke-Eversloh, T., & Stephanopoulos, G. (2005). Feedback inhibition of chorismate mutase/prephenate dehydrogenase (TyrA) of Escherichia coli: Generation and characterization of tyrosine-insensitive mutants. Applied and Environmental Microbiology, 71, 7224–7228
25. Lütke-Eversloh, T., & Stephanopoulos, G. (2007). l-Tyrosine production by deregulated strains of Escherichia coli. Applied Microbiology and Biotechnology, 75, 103–110
26. Lütke-Eversloh, T., & Stephanopoulos, G. (2008). Combinatorial pathway analysis for improved l-tyrosine production in Escherichia coli: Identification of enzymatic bottlenecks by systematic gene overexpression. Metabolic Engineering, 10, 69–77
27. Na, D., Yoo, S. M., Chung, H., Park, H., Park, J. H., & Lee, S. Y. (2013). Metabolic engineering of Escherichia coli using synthetic small regulatory RNAs. Nature Biotechnology, 31, 170–174
28. Park, S. Y., Yang, D., Ha, S. H., & Lee, S. Y. (2018). Metabolic engineering of microorganisms for the production of natural compounds. Advanced Biosystems, 2, 1700190
29. Patnaik, R., Zolandz, R. R., Green, D. A., & Kraynie, D. F. (2008). l-Tyrosine production by recombinant Escherichia coli: Fermentation optimization and recovery. Biotechnology and Bioengineering, 99, 741–752
30. Pittard, J., Camakaris, H., & Yang, J. (2005). The TyrR regulon. Molecular Microbiology, 55, 16–26
31. Rodriguez, A., Martnez, J. A., Flores, N., Escalante, A., Gosset, G., & Bolivar, F. (2014). Engineering Escherichia coli to overproduce aromatic amino acids and derived compounds. Microbial Cell Factories, 13, 126
32. Sambrook, J., & Russell, D. W. (2001). Molecular cloning: A laboratory manual. CSHL press
33. Santos, C. N. S., Xiao, W., & Stephanopoulos, G. (2012). Rational, combinatorial, and genomic approaches for engineering l-tyrosine production in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America, 109, 13538–13543
34. Sørensen, H. P., & Mortensen, K. K. (2005). Advanced genetic strategies for recombinant protein expression in Escherichia coli. Journal of Biotechnology, 115, 113–128
35. Szenk, M., Dill, K. A., & de Graff, A. M. R. (2017). Why do fast-growing bacteria enter overflow metabolism? Testing the membrane real estate hypothesis. Cell Systems, 5, 95–104
36. Torella, J. P., Boehm, C. R., Lienert, F., Chen, J. H., Way, J. C., & Silver, P. A. (2014a). Rapid construction of insulated genetic circuits via synthetic sequence-guided isothermal assembly. Nucleic Acids Research, 42, 681–689
37. Torella, J. P., Lienert, F., Boehm, C. R., Chen, J. H., Way, J. C., & Silver, P. A. (2014b). Unique nucleotide sequence-guided assembly of repetitive DNA parts for synthetic biology applications. Nature Protocols, 9, 2075–2089
38. Whipp, M. J., & Pittard, A. J. (1977). Regulation of aromatic amino acid transport systems in Escherichia coli K-12. Journal of Bacteriology, 132, 453–461
39. Yang, J. E., Park, S. J., Kim, W. J., Kim, H. J., Kim, B. J., Lee, H., … Lee, S. Y. (2018). One-step fermentative production of aromatic polyesters from glucose by metabolically engineered Escherichia coli strains. Nature Communications, 9, 79
40. Yoo, S. M., Na, D., & Lee, S. Y. (2013). Design and use of synthetic regulatory small RNAs to control gene expression in Escherichia coli. Nature Protocols, 8, 1694–1707
41. Zhao, G., Xia, T., Ingram, L. O., & Jensen, R. A. (1993). An allosterically insensitive class of cyclohexadienyl dehydrogenase from Zymomonas mobilis. European Journal of Biochemistry, 212, 157–165
42. Zhao, S., Jones, J. A., Lachance, D. M., Bhan, N., Khalidi, O., Venkataraman, S., … Koffas, M. A. G. (2015). Improvement of catechin production in Escherichia coli through combinatorial metabolic engineering. Metabolic Engineering, 28, 43–53