Improving fatty acids production by engineering dynamic pathway regulation and metabolic control

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 31, 2014, Pages 11299-11304

  Xu, Peng ^a,b   Li, Lingyun ^a,b   Zhang, Fuming ^a,b   Stephanopoulos, Gregory ^c   Koffas, Mattheos ^a,b  

^a RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^b RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^c Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

Biofuels; Dynamic metabolic control; Transcriptional regulation

Indexed keywords

FATTY ACID DERIVATIVE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MALONYL COENZYME A; RNA POLYMERASE;

ARTICLE; BACTERIAL STRAIN; BINDING AFFINITY; BINDING SITE; CELL GROWTH; CHEMICAL STRUCTURE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA BINDING; ESCHERICHIA COLI; FATTY ACID SYNTHESIS; GENE ACTIVATION; GENE EXPRESSION; GENE SWITCHING; METABOLIC ENGINEERING; METABOLIC REGULATION; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; REPORTER GENE; SURFACE PLASMON RESONANCE; TRANSCRIPTION INITIATION; WILD TYPE;

BIOFUELS; DYNAMIC METABOLIC CONTROL; TRANSCRIPTIONAL REGULATION;

BIOSYNTHETIC PATHWAYS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FATTY ACIDS; GENE EXPRESSION REGULATION, BACTERIAL; MALONYL COENZYME A; METABOLIC ENGINEERING; TRANSCRIPTION FACTORS;

EID: 84905668376     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1406401111     Document Type: Article

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