-
1
-
-
85011999800
-
Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: Example lists and criteria for their selection and use
-
Aschner, M., Ceccatelli, S., Daneshian, M. et al. (2017). Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: Example lists and criteria for their selection and use. ALTEX 34, 49-74. doi:10.14573/altex.1604201
-
(2017)
ALTEX
, vol.34
, pp. 49-74
-
-
Aschner, M.1
Ceccatelli, S.2
Daneshian, M.3
-
2
-
-
84922032722
-
International stakeholder network (ISTNET): Creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes
-
Bal-Price, A., Crofton, K. M., Leist, M. et al. (2015). International stakeholder network (ISTNET): Creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes. Arch Toxicol 89, 269-287. doi:10.1007/s00204-015-1464-2
-
(2015)
Arch Toxicol
, vol.89
, pp. 269-287
-
-
Bal-Price, A.1
Crofton, K. M.2
Leist, M.3
-
3
-
-
84865776716
-
Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome
-
Balmer, N. V., Weng, M. K., Zimmer, B. et al. (2012). Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome. Hum Mol Genet 21, 4104-4114. doi:10.1093/hmg/ dds239
-
(2012)
Hum Mol Genet
, vol.21
, pp. 4104-4114
-
-
Balmer, N. V.1
Weng, M. K.2
Zimmer, B.3
-
5
-
-
84937846473
-
Comparative human and rat neurospheres reveal species differences in chemical effects on neurodevelopmental key events
-
Baumann, J., Gassmann, K., Masjosthusmann, S. et al. (2016). Comparative human and rat neurospheres reveal species differences in chemical effects on neurodevelopmental key events. Arch Toxicol 90, 1415-1427. doi:10.1007/s00204-015-1568-8
-
(2016)
Arch Toxicol
, vol.90
, pp. 1415-1427
-
-
Baumann, J.1
Gassmann, K.2
Masjosthusmann, S.3
-
6
-
-
84977118072
-
Project TENDR: Targeting environmental neuro-developmental risks the TENDR consensus statement
-
Bennett, D., Bellinger, D. C., Birnbaum, L. S. et al. (2016). Project TENDR: Targeting environmental neuro-developmental risks the TENDR consensus statement. Environ Health Perspect 124, A118-122. doi:10.1289/ehp358
-
(2016)
Environ Health Perspect
, vol.124
, pp. A118-A122
-
-
Bennett, D.1
Bellinger, D. C.2
Birnbaum, L. S.3
-
7
-
-
85018424306
-
Assaying spontaneous network activity and cellular viability using multi-well microelectrode arrays
-
Brown, J. P., Lynch, B. S., Curry-Chisolm, I. M. et al. (2017). Assaying spontaneous network activity and cellular viability using multi-well microelectrode arrays. Methods Mol Biol 1601, 153-170. doi:10.1007/978-1-4939-6960-9_13
-
(2017)
Methods Mol Biol
, vol.1601
, pp. 153-170
-
-
Brown, J. P.1
Lynch, B. S.2
Curry-Chisolm, I. M.3
-
8
-
-
85172758065
-
Experimental and clinical neurotoxicology. Second edition
-
Cavanagh, J. B. (2000). Experimental and clinical neurotoxicology. Second edition. Brain 123, 2571-2573. doi:10.1093/ brain/123.12.2571
-
(2000)
Brain
, vol.123
, pp. 2571-2573
-
-
Cavanagh, J. B.1
-
9
-
-
79958270042
-
Developmental neurotoxicity testing: Recommendations for developing alternative methods for the screening and prioritization of chemicals
-
Crofton, K. M., Mundy, W. R., Lein, P. J. et al. (2011). Developmental neurotoxicity testing: Recommendations for developing alternative methods for the screening and prioritization of chemicals. ALTEX 28, 9-15. doi:10.14573/altex.2011.1.009
-
(2011)
ALTEX
, vol.28
, pp. 9-15
-
-
Crofton, K. M.1
Mundy, W. R.2
Lein, P. J.3
-
10
-
-
84865560583
-
Developmental neurotoxicity testing: A path forward
-
Crofton, K. M., Mundy, W. R. and Shafer, T. J. (2012). Developmental neurotoxicity testing: A path forward. Congenit Anom (Kyoto) 52, 140-146. doi:10.1111/j.1741-4520.2012.00377.x
-
(2012)
Congenit Anom (Kyoto)
, vol.52
, pp. 140-146
-
-
Crofton, K. M.1
Mundy, W. R.2
Shafer, T. J.3
-
11
-
-
84901820244
-
International stakeholder network (ISTNET) for creating a developmental neurotoxicity testing (DNT) roadmap for regulatory purposes
-
Crofton, K., Fritsche, E., Ylikomi, T. et al. (2014). International stakeholder network (ISTNET) for creating a developmental neurotoxicity testing (DNT) roadmap for regulatory purposes. ALTEX 31, 223-224. doi:10.14573/altex.1402121
-
(2014)
ALTEX
, vol.31
, pp. 223-224
-
-
Crofton, K.1
Fritsche, E.2
Ylikomi, T.3
-
12
-
-
84871716691
-
Comparison of chemical-induced changes in proliferation and apoptosis in human and mouse neuroprogenitor cells
-
Culbreth, M. E., Harrill, J. A., Freudenrich, T. M. et al. (2012). Comparison of chemical-induced changes in proliferation and apoptosis in human and mouse neuroprogenitor cells. Neurotoxicology 33, 1499-1510. doi:10.1016/j.neuro.2012.05.012
-
(2012)
Neurotoxicology
, vol.33
, pp. 1499-1510
-
-
Culbreth, M. E.1
Harrill, J. A.2
Freudenrich, T. M.3
-
13
-
-
84961653980
-
Highlight report: Launch of a large integrated European in vitro toxicology project: EU-ToxRisk
-
Daneshian, M., Kamp, H., Hengstler, J. et al. (2016). Highlight report: Launch of a large integrated European in vitro toxicology project: EU-ToxRisk. Arch Toxicol 90, 1021-1024. doi:10.1007/s00204-016-1698-7
-
(2016)
Arch Toxicol
, vol.90
, pp. 1021-1024
-
-
Daneshian, M.1
Kamp, H.2
Hengstler, J.3
-
14
-
-
70349919668
-
Suitability of GRIND-based principal properties for the description of molecular similarity and ligand-based virtual screening
-
Duran, A., Zamora, I. and Pastor, M. (2009). Suitability of GRIND-based principal properties for the description of molecular similarity and ligand-based virtual screening. J Chem Inf Model 49, 2129-2138. doi:10.1021/ci900228x
-
(2009)
J Chem Inf Model
, vol.49
, pp. 2129-2138
-
-
Duran, A.1
Zamora, I.2
Pastor, M.3
-
15
-
-
84987645985
-
State of the art in non-animal approaches for skin sensitization testing: From individual test methods towards testing strategies
-
Ezendam, J., Braakhuis, H. M. and Vandebriel, R. J. (2016). State of the art in non-animal approaches for skin sensitization testing: From individual test methods towards testing strategies. Arch Toxicol 90, 2861-2883. doi:10.1007/s00204-016-1842-4
-
(2016)
Arch Toxicol
, vol.90
, pp. 2861-2883
-
-
Ezendam, J.1
Braakhuis, H. M.2
Vandebriel, R. J.3
-
16
-
-
80855143608
-
Effects of sub-lethal neurite outgrowth inhibitory concentrations of chlorpyrifos oxon on cytoskeletal proteins and acetylcholinesterase in differentiating N2a cells
-
Flaskos, J., Nikolaidis, E., Harris, W. et al. (2011). Effects of sub-lethal neurite outgrowth inhibitory concentrations of chlorpyrifos oxon on cytoskeletal proteins and acetylcholinesterase in differentiating N2a cells. Toxicol Appl Pharmacol 256, 330-336. doi:10.1016/j.taap.2011.06.002
-
(2011)
Toxicol Appl Pharmacol
, vol.256
, pp. 330-336
-
-
Flaskos, J.1
Nikolaidis, E.2
Harris, W.3
-
17
-
-
77949388450
-
The network formation assay: A spatially standardized neurite outgrowth analytical display for neurotoxicity screening
-
Frimat, J. P., Sisnaiske, J., Subbiah, S. et al. (2010). The network formation assay: A spatially standardized neurite outgrowth analytical display for neurotoxicity screening. Lab Chip 10, 701-709. doi:10.1039/b922193j
-
(2010)
Lab Chip
, vol.10
, pp. 701-709
-
-
Frimat, J. P.1
Sisnaiske, J.2
Subbiah, S.3
-
18
-
-
22144449590
-
Polychlorinated biphenyls disturb differentiation of normal human neural progenitor cells: Clue for involvement of thyroid hormone receptors
-
Fritsche, E., Cline, J. E., Nguyen, N.-H. et al. (2005). Polychlorinated biphenyls disturb differentiation of normal human neural progenitor cells: Clue for involvement of thyroid hormone receptors. Environ Health Perspect 113, 871-876. doi:10.1289/ehp.7793
-
(2005)
Environ Health Perspect
, vol.113
, pp. 871-876
-
-
Fritsche, E.1
Cline, J. E.2
Nguyen, N.-H.3
-
19
-
-
85018644461
-
OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes
-
Fritsche, E., Crofton, K. M., Hernandez, A. F. et al. (2017). OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes. ALTEX 34, 311-315. doi:10.14573/altex.1701171
-
(2017)
ALTEX
, vol.34
, pp. 311-315
-
-
Fritsche, E.1
Crofton, K. M.2
Hernandez, A. F.3
-
20
-
-
33845424655
-
Developmental neurotoxicity of industrial chemicals
-
Grandjean, P. and Landrigan, P. J. (2006). Developmental neurotoxicity of industrial chemicals. Lancet 368, 2167-2178. doi:10.1016/S0140-6736(06)69665-7
-
(2006)
Lancet
, vol.368
, pp. 2167-2178
-
-
Grandjean, P.1
Landrigan, P. J.2
-
21
-
-
84894029844
-
Neurobehavioural effects of developmental toxicity
-
Grandjean, P. and Landrigan, P. J. (2014). Neurobehavioural effects of developmental toxicity. Lancet Neurol 13, 330-338. doi:10.1016/S1474-4422(13)70278-3
-
(2014)
Lancet Neurol
, vol.13
, pp. 330-338
-
-
Grandjean, P.1
Landrigan, P. J.2
-
22
-
-
80052941505
-
Quantitative assessment of neurite outgrowth in PC12 cells
-
Harrill, J. A. and Mundy, W. R. (2011). Quantitative assessment of neurite outgrowth in PC12 cells. Methods Mol Biol 758, 331-348. doi:10.1007/978-1-61779-170-3_23
-
(2011)
Methods Mol Biol
, vol.758
, pp. 331-348
-
-
Harrill, J. A.1
Mundy, W. R.2
-
23
-
-
80855131654
-
Comparative sensitivity of human and rat neural cultures to chemical-induced inhibition of neurite outgrowth
-
Harrill, J. A., Freudenrich, T. M., Robinette, B. L. and Mundy, W. R. (2011). Comparative sensitivity of human and rat neural cultures to chemical-induced inhibition of neurite outgrowth. Toxicol Appl Pharmacol 256, 268-280. doi:10.1016/j. taap.2011.02.013
-
(2011)
Toxicol Appl Pharmacol
, vol.256
, pp. 268-280
-
-
Harrill, J. A.1
Freudenrich, T. M.2
Robinette, B. L.3
Mundy, W. R.4
-
24
-
-
84870357944
-
Use of high content image analyses to detect chemical-mediated effects on neurite sub-populations in primary rat cortical neurons
-
Harrill, J. A., Robinette, B. L., Freudenrich, T. and Mundy, W. R. (2013). Use of high content image analyses to detect chemical-mediated effects on neurite sub-populations in primary rat cortical neurons. Neurotoxicology 34, 61-73. doi:10.1016/j. neuro.2012.10.013
-
(2013)
Neurotoxicology
, vol.34
, pp. 61-73
-
-
Harrill, J. A.1
Robinette, B. L.2
Freudenrich, T.3
Mundy, W. R.4
-
25
-
-
84876323285
-
Food for thought … Integrated testing strategies for safety assessments
-
Hartung, T., Luechtefeld, T., Maertens, A. and Kleensang, A. (2013). Food for thought … Integrated testing strategies for safety assessments. ALTEX 30, 3-18. doi:10.14573/ altex.2013.1.003
-
(2013)
ALTEX
, vol.30
, pp. 3-18
-
-
Hartung, T.1
Luechtefeld, T.2
Maertens, A.3
Kleensang, A.4
-
26
-
-
84961258170
-
Stem cell-derived immature human dorsal root ganglia neurons to identify peripheral neurotoxicants
-
Hoelting, L., Klima, S., Karreman, C. et al. (2016). Stem cell-derived immature human dorsal root ganglia neurons to identify peripheral neurotoxicants. Stem Cells Transl Med 5, 476-487. doi:10.5966/sctm.2015-0108
-
(2016)
Stem Cells Transl Med
, vol.5
, pp. 476-487
-
-
Hoelting, L.1
Klima, S.2
Karreman, C.3
-
27
-
-
61349100071
-
Gene expression as a sensitive endpoint to evaluate cell differentiation and maturation of the developing central nervous system in primary cultures of rat cerebellar granule cells (CGCs) exposed to pesticides
-
Hogberg, H. T., Kinsner-Ovaskainen, A., Hartung, T. et al. (2009). Gene expression as a sensitive endpoint to evaluate cell differentiation and maturation of the developing central nervous system in primary cultures of rat cerebellar granule cells (CGCs) exposed to pesticides. Toxicol Appl Pharmacol 235, 268-286. doi:10.1016/j.taap.2008.12.014
-
(2009)
Toxicol Appl Pharmacol
, vol.235
, pp. 268-286
-
-
Hogberg, H. T.1
Kinsner-Ovaskainen, A.2
Hartung, T.3
-
28
-
-
75249106472
-
mRNA expression is a relevant tool to identify developmental neurotoxicants using an in vitro approach
-
Hogberg, H. T., Kinsner-Ovaskainen, A., Coecke, S. et al. (2010). mRNA expression is a relevant tool to identify developmental neurotoxicants using an in vitro approach. Toxicol Sci 113, 95-115. doi:10.1093/toxsci/kfp175
-
(2010)
Toxicol Sci
, vol.113
, pp. 95-115
-
-
Hogberg, H. T.1
Kinsner-Ovaskainen, A.2
Coecke, S.3
-
29
-
-
23744456959
-
Chlorpyrifos exerts opposing effects on axonal and dendritic growth in primary neuronal cultures
-
Howard, A. S., Bucelli, R., Jett, D. A. et al. (2005). Chlorpyrifos exerts opposing effects on axonal and dendritic growth in primary neuronal cultures. Toxicol Appl Pharmacol 207, 112-124. doi:10.1016/j.taap.2004.12.008
-
(2005)
Toxicol Appl Pharmacol
, vol.207
, pp. 112-124
-
-
Howard, A. S.1
Bucelli, R.2
Jett, D. A.3
-
30
-
-
79955724481
-
Integrated testing strategy (ITS) – Opportunities to better use existing data and guide future testing in toxicology
-
Jaworska, J. and Hoffmann, S. (2010). Integrated testing strategy (ITS) – Opportunities to better use existing data and guide future testing in toxicology. ALTEX 27, 231-242. doi:10.14573/altex.2010.4.231
-
(2010)
ALTEX
, vol.27
, pp. 231-242
-
-
Jaworska, J.1
Hoffmann, S.2
-
31
-
-
84902120685
-
In vitro and modelling approaches to risk assessment from the U.S. Environmental protection agency toxcast programme
-
Judson, R., Houck, K., Martin, M. et al. (2014). In vitro and modelling approaches to risk assessment from the U.S. Environmental protection agency toxcast programme. Basic Clin Pharmacol Toxicol 115, 69-76. doi:10.1111/bcpt.12239
-
(2014)
Basic Clin Pharmacol Toxicol
, vol.115
, pp. 69-76
-
-
Judson, R.1
Houck, K.2
Martin, M.3
-
32
-
-
84947781653
-
Integrated model of chemical perturbations of a biological pathway using 18 in vitro high-throughput screening assays for the estrogen receptor
-
Judson, R. S., Magpantay, F. M., Chickarmane, V. et al. (2015). Integrated model of chemical perturbations of a biological pathway using 18 in vitro high-throughput screening assays for the estrogen receptor. Toxicol Sci 148, 137-154. doi:10.1093/toxsci/kfv168
-
(2015)
Toxicol Sci
, vol.148
, pp. 137-154
-
-
Judson, R. S.1
Magpantay, F. M.2
Chickarmane, V.3
-
33
-
-
84992690576
-
Analysis of the effects of cell stress and cytotoxicity on in vitro assay activity across a diverse chemical and assay space
-
Judson, R., Houck, K., Martin, M. et al. (2016). Analysis of the effects of cell stress and cytotoxicity on in vitro assay activity across a diverse chemical and assay space. Toxicol Sci 152, 323-339. doi:10.1093/toxsci/kfw092
-
(2016)
Toxicol Sci
, vol.152
, pp. 323-339
-
-
Judson, R.1
Houck, K.2
Martin, M.3
-
34
-
-
79951679077
-
A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins
-
Kirkland, D., Reeve, L., Gatehouse, D. et al. (2011). A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins. Mutat Res 721, 27-73. doi:10.1016/j.mrgentox.2010.12.015
-
(2011)
Mutat Res
, vol.721
, pp. 27-73
-
-
Kirkland, D.1
Reeve, L.2
Gatehouse, D.3
-
35
-
-
84890566643
-
Evaluation of a human neurite growth assay as specific screen for developmental neurotoxicants
-
Krug, A. K., Balmer, N. V., Matt, F. et al. (2013). Evaluation of a human neurite growth assay as specific screen for developmental neurotoxicants. Arch Toxicol 87, 2215-2231. doi:10.1007/s00204-013-1072-y
-
(2013)
Arch Toxicol
, vol.87
, pp. 2215-2231
-
-
Krug, A. K.1
Balmer, N. V.2
Matt, F.3
-
37
-
-
59849124092
-
The dawning of a new age of toxicology
-
Leist, M., Hartung, T. and Nicotera, P. (2008a). The dawning of a new age of toxicology. ALTEX 25, 103-114. doi:10.14573/ altex.2008.2.103
-
(2008)
ALTEX
, vol.25
, pp. 103-114
-
-
Leist, M.1
Hartung, T.2
Nicotera, P.3
-
38
-
-
48949091622
-
Food for thought ... On the real success of 3R approaches
-
Leist, M., Kadereit, S. and Schildknecht, S. (2008b). Food for thought ... On the real success of 3R approaches. ALTEX 25, 17-32. doi:10.14573/altex.2008.1.17
-
(2008)
ALTEX
, vol.25
, pp. 17-32
-
-
Leist, M.1
Kadereit, S.2
Schildknecht, S.3
-
39
-
-
79955432219
-
Food for thought ... Considerations and guidelines for basic test method descriptions in toxicology
-
Leist, M., Efremova, L. and Karreman, C. (2010). Food for thought ... Considerations and guidelines for basic test method descriptions in toxicology. ALTEX 27, 309-317. doi:10.14573/altex.2010.4.309
-
(2010)
ALTEX
, vol.27
, pp. 309-317
-
-
Leist, M.1
Efremova, L.2
Karreman, C.3
-
40
-
-
84864593532
-
Validation and quality control of replacement alternatives – Current status and future challenges
-
Leist, M., Hasiwa, N., Daneshian, M. and Hartung, T. (2012). Validation and quality control of replacement alternatives – Current status and future challenges. Toxicol Res 1, 8-22. doi:10.1039/c2tx20011b
-
(2012)
Toxicol Res
, vol.1
, pp. 8-22
-
-
Leist, M.1
Hasiwa, N.2
Daneshian, M.3
Hartung, T.4
-
41
-
-
84904901979
-
Consensus report on the future of animal-free systemic toxicity testing
-
Leist, M., Hasiwa, N., Rovida, C. et al. (2014). Consensus report on the future of animal-free systemic toxicity testing. ALTEX 31, 341-356. doi:10.14573/altex.1406091
-
(2014)
ALTEX
, vol.31
, pp. 341-356
-
-
Leist, M.1
Hasiwa, N.2
Rovida, C.3
-
42
-
-
85035790758
-
The borderline range of toxicological methods: Quantification and implications for evaluating precision
-
Leontaridou, M., Urbisch, D., Kolle, S. N. et al. (2017). The borderline range of toxicological methods: Quantification and implications for evaluating precision. ALTEX 34, 525-538. doi:10.14573/altex.1606271
-
(2017)
ALTEX
, vol.34
, pp. 525-538
-
-
Leontaridou, M.1
Urbisch, D.2
Kolle, S. N.3
-
43
-
-
0037064078
-
Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line
-
Lotharius, J., Barg, S., Wiekop, P. et al. (2002). Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line. J Biol Chem 277, 38884-38894. doi:10.1074/jbc.M205518200
-
(2002)
J Biol Chem
, vol.277
, pp. 38884-38894
-
-
Lotharius, J.1
Barg, S.2
Wiekop, P.3
-
44
-
-
21844442345
-
Progressive degeneration of human mesencephalic neuron-derived cells triggered by dopamine-dependent oxidative stress is dependent on the mixed-lineage kinase pathway
-
Lotharius, J., Falsig, J., van Beek, J. et al. (2005). Progressive degeneration of human mesencephalic neuron-derived cells triggered by dopamine-dependent oxidative stress is dependent on the mixed-lineage kinase pathway. J Neurosci 25, 6329-6342. doi:10.1523/JNEUROSCI.1746-05.2005
-
(2005)
J Neurosci
, vol.25
, pp. 6329-6342
-
-
Lotharius, J.1
Falsig, J.2
van Beek, J.3
-
45
-
-
60749100386
-
A retrospective performance assessment of the developmental neurotoxicity study in support of OECD test guideline 426
-
Makris, S. L., Raffaele, K., Allen, S. et al. (2009). A retrospective performance assessment of the developmental neurotoxicity study in support of OECD test guideline 426. Environ Health Perspect 117, 17-25. doi:10.1289/ehp.11447
-
(2009)
Environ Health Perspect
, vol.117
, pp. 17-25
-
-
Makris, S. L.1
Raffaele, K.2
Allen, S.3
-
46
-
-
84979255712
-
Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing
-
Marx, U., Andersson, T. B., Bahinski, A. et al. (2016). Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing. ALTEX 33, 272-321. doi:10.14573/altex.1603161
-
(2016)
ALTEX
, vol.33
, pp. 272-321
-
-
Marx, U.1
Andersson, T. B.2
Bahinski, A.3
-
47
-
-
37249023309
-
New and original pKa prediction method using grid molecular interaction fields
-
Milletti, F., Storchi, L., Sforna, G. and Cruciani, G. (2007). New and original pKa prediction method using grid molecular interaction fields. J Chem Inf Model 47, 2172-2181. doi:10.1021/ci700018y
-
(2007)
J Chem Inf Model
, vol.47
, pp. 2172-2181
-
-
Milletti, F.1
Storchi, L.2
Sforna, G.3
Cruciani, G.4
-
48
-
-
84944718074
-
Expanding the test set: Chemicals with potential to disrupt mammalian brain development
-
Mundy, W. R., Padilla, S., Breier, J. M. et al. (2015). Expanding the test set: Chemicals with potential to disrupt mammalian brain development. Neurotoxicol Teratol 52, 25-35. doi:10.1016/j.ntt.2015.10.001
-
(2015)
Neurotoxicol Teratol
, vol.52
, pp. 25-35
-
-
Mundy, W. R.1
Padilla, S.2
Breier, J. M.3
-
49
-
-
85018724518
-
Combination of multiple neural crest migration assays to identify environmental toxicants from a proof-of-concept chemical library
-
Nyffeler, J., Dolde, X., Krebs, A. et al. (2017a). Combination of multiple neural crest migration assays to identify environmental toxicants from a proof-of-concept chemical library. Arch Toxicol 91, 3613–3632. doi:10.1007/s00204-017-1977-y
-
(2017)
Arch Toxicol
, vol.91
, pp. 3613-3632
-
-
Nyffeler, J.1
Dolde, X.2
Krebs, A.3
-
50
-
-
85012008949
-
Design of a high-throughput human neural crest cell migration assay to indicate potential developmental toxicants
-
Nyffeler, J., Karreman, C., Leisner, H. et al. (2017b). Design of a high-throughput human neural crest cell migration assay to indicate potential developmental toxicants. ALTEX 34, 75-94. doi:10.14573/altex.1605031
-
(2017)
ALTEX
, vol.34
, pp. 75-94
-
-
Nyffeler, J.1
Karreman, C.2
Leisner, H.3
-
52
-
-
85026243203
-
A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity
-
Pamies, D., Barreras, P., Block, K. et al. (2016). A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity. ALTEX 34, 362-376. doi:10.14573/altex.1609122
-
(2016)
ALTEX
, vol.34
, pp. 362-376
-
-
Pamies, D.1
Barreras, P.2
Block, K.3
-
53
-
-
84877604097
-
Uncertainty of testing methods – What do we (want to) know?
-
Paparella, M., Daneshian, M., Hornek-Gausterer, R. et al. (2013). Uncertainty of testing methods – What do we (want to) know? ALTEX 30, 131-144. doi:10.14573/altex.2013.2.131
-
(2013)
ALTEX
, vol.30
, pp. 131-144
-
-
Paparella, M.1
Daneshian, M.2
Hornek-Gausterer, R.3
-
54
-
-
85018622397
-
Uncertainties of testing methods: What do we (want to) know about carcinogenicity?
-
Paparella, M., Colacci, A. and Jacobs, M. N. (2017). Uncertainties of testing methods: What do we (want to) know about carcinogenicity? ALTEX 34, 235-252. doi:10.14573/ altex.1608281
-
(2017)
ALTEX
, vol.34
, pp. 235-252
-
-
Paparella, M.1
Colacci, A.2
Jacobs, M. N.3
-
55
-
-
0034710718
-
Grid-independent descriptors (GRIND): A novel class of alignment-independent three-dimensional molecular descriptors
-
Pastor, M., Cruciani, G., McLay, I. et al. (2000). Grid-independent descriptors (GRIND): A novel class of alignment-independent three-dimensional molecular descriptors. J Med Chem 43, 3233-3243. doi:10.1021/jm000941m
-
(2000)
J Med Chem
, vol.43
, pp. 3233-3243
-
-
Pastor, M.1
Cruciani, G.2
McLay, I.3
-
56
-
-
84939857473
-
Comparative neurotoxicity screening in human iPSC-derived neural stem cells, neurons and astrocytes
-
Pei, Y., Peng, J., Behl, M. et al. (2016). Comparative neurotoxicity screening in human iPSC-derived neural stem cells, neurons and astrocytes. Brain Res 1638, 57-73. doi:10.1016/j. brainres.2015.07.048
-
(2016)
Brain Res
, vol.1638
, pp. 57-73
-
-
Pei, Y.1
Peng, J.2
Behl, M.3
-
57
-
-
85013231143
-
The isolated chicken eye test to replace the Draize test in rabbits
-
Prinsen, M. K., Hendriksen, C. F., Krul, C. A. and Woutersen, R. A. (2017). The isolated chicken eye test to replace the Draize test in rabbits. Regul Toxicol Pharmacol 85, 132-149. doi:10.1016/j.yrtph.2017.01.009
-
(2017)
Regul Toxicol Pharmacol
, vol.85
, pp. 132-149
-
-
Prinsen, M. K.1
Hendriksen, C. F.2
Krul, C. A.3
Woutersen, R. A.4
-
58
-
-
84959358615
-
Neurite outgrowth in human induced pluripotent stem cell-derived neurons as a high-throughput screen for developmental neurotoxicity or neurotoxicity
-
Ryan, K. R., Sirenko, O., Parham, F. et al. (2016). Neurite outgrowth in human induced pluripotent stem cell-derived neurons as a high-throughput screen for developmental neurotoxicity or neurotoxicity. Neurotoxicology 53, 271-281. doi:10.1016/j.neuro.2016.02.003
-
(2016)
Neurotoxicology
, vol.53
, pp. 271-281
-
-
Ryan, K. R.1
Sirenko, O.2
Parham, F.3
-
59
-
-
0028466540
-
Comparison of automatic three-dimensional model builders using 639 x-ray structures
-
Sadowski, J., Gasteiger, J. and Klebe, G. (1994). Comparison of automatic three-dimensional model builders using 639 x-ray structures. J Chem Inf Comput Sci 34, 1000-1008. doi:10.1021/ci00020a039
-
(1994)
J Chem Inf Comput Sci
, vol.34
, pp. 1000-1008
-
-
Sadowski, J.1
Gasteiger, J.2
Klebe, G.3
-
60
-
-
70350031056
-
Requirement of a dopaminergic neuronal phenotype for toxicity of low concentrations of 1-methyl-4-phenylpyridinium to human cells
-
Schildknecht, S., Poltl, D., Nagel, D. M. et al. (2009). Requirement of a dopaminergic neuronal phenotype for toxicity of low concentrations of 1-methyl-4-phenylpyridinium to human cells. Toxicol Appl Pharmacol 241, 23-35. doi:10.1016/j. taap.2009.07.027
-
(2009)
Toxicol Appl Pharmacol
, vol.241
, pp. 23-35
-
-
Schildknecht, S.1
Poltl, D.2
Nagel, D. M.3
-
61
-
-
84893041165
-
Generation of genetically-modified human differentiated cells for toxicological tests and the study of neurodegenerative diseases
-
Schildknecht, S., Karreman, C., Poltl, D. et al. (2013). Generation of genetically-modified human differentiated cells for toxicological tests and the study of neurodegenerative diseases. ALTEX 30, 427-444. doi:10.14573/altex.2013.4.427
-
(2013)
ALTEX
, vol.30
, pp. 427-444
-
-
Schildknecht, S.1
Karreman, C.2
Poltl, D.3
-
62
-
-
85018794797
-
Tipping points and endogenous determinants of nigrostriatal degeneration by MPTP
-
Schildknecht, S., Di Monte, D. A., Pape, R. et al. (2017). Tipping points and endogenous determinants of nigrostriatal degeneration by MPTP. Trends Pharmacol Sci 38, 541-555. doi:10.1016/j.tips.2017.03.010
-
(2017)
Trends Pharmacol Sci
, vol.38
, pp. 541-555
-
-
Schildknecht, S.1
Di Monte, D. A.2
Pape, R.3
-
63
-
-
84983002040
-
In vitro acute and developmental neurotoxicity screening: An overview of cellular platforms and high-throughput technical possibilities
-
Schmidt, B. Z., Lehmann, M., Gutbier, S. et al. (2017). In vitro acute and developmental neurotoxicity screening: An overview of cellular platforms and high-throughput technical possibilities. Arch Toxicol 91, 1-33. doi:10.1007/s00204-016-1805-9
-
(2017)
Arch Toxicol
, vol.91
, pp. 1-33
-
-
Schmidt, B. Z.1
Lehmann, M.2
Gutbier, S.3
-
64
-
-
84990890584
-
Omnisphero: A high-content image analysis (HCA) approach for phenotypic developmental neurotoxicity (DNT) screenings of organoid neurosphere cultures in vitro
-
Schmuck, M. R., Temme, T., Dach, K. et al. (2017). Omnisphero: A high-content image analysis (HCA) approach for phenotypic developmental neurotoxicity (DNT) screenings of organoid neurosphere cultures in vitro. Arch Toxicol 91, 2017-2028. doi:10.1007/s00204-016-1852-2
-
(2017)
Arch Toxicol
, vol.91
, pp. 2017-2028
-
-
Schmuck, M. R.1
Temme, T.2
Dach, K.3
-
65
-
-
81055127451
-
Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line
-
Scholz, D., Poltl, D., Genewsky, A. et al. (2011). Rapid, complete and large-scale generation of post-mitotic neurons from the human LUHMES cell line. J Neurochem 119, 957-971. doi:10.1111/j.1471-4159.2011.07255.x
-
(2011)
J Neurochem
, vol.119
, pp. 957-971
-
-
Scholz, D.1
Poltl, D.2
Genewsky, A.3
-
66
-
-
84969242925
-
Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: Introduction of the STOP-Toxukn and STOP-Toxukk tests
-
Shinde, V., Hoelting, L., Srinivasan, S. P. et al. (2017). Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: Introduction of the STOP-Toxukn and STOP-Toxukk tests. Arch Toxicol 91, 839-864. doi:10.1007/s00204-016-1741-8
-
(2017)
Arch Toxicol
, vol.91
, pp. 839-864
-
-
Shinde, V.1
Hoelting, L.2
Srinivasan, S. P.3
-
67
-
-
85015061049
-
In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model
-
Sirenko, O., Grimm, F. A., Ryan, K. R. et al. (2017). In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model. Toxicol Appl Pharmacol 322, 60-74. doi:10.1016/j. taap.2017.02.020
-
(2017)
Toxicol Appl Pharmacol
, vol.322
, pp. 60-74
-
-
Sirenko, O.1
Grimm, F. A.2
Ryan, K. R.3
-
69
-
-
84949509769
-
A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis
-
Smirnova, L., Harris, G., Delp, J. et al. (2016). A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis. Arch Toxicol 90, 2725-2743. doi:10.1007/s00204-015-1637-z
-
(2016)
Arch Toxicol
, vol.90
, pp. 2725-2743
-
-
Smirnova, L.1
Harris, G.2
Delp, J.3
-
70
-
-
0016593776
-
Nervous system degeneration produced by acrylamide monomer
-
Spencer, P. S. and Schaumburg, H. H. (1975). Nervous system degeneration produced by acrylamide monomer. Environ Health Perspect 11, 129-133. doi:10.1289/ehp.7511129
-
(1975)
Environ Health Perspect
, vol.11
, pp. 129-133
-
-
Spencer, P. S.1
Schaumburg, H. H.2
-
71
-
-
79955379993
-
Assessment of chemical-induced impairment of human neurite outgrowth by multiparametric live cell imaging in high-density cultures
-
Stiegler, N. V., Krug, A. K., Matt, F. and Leist, M. (2011). Assessment of chemical-induced impairment of human neurite outgrowth by multiparametric live cell imaging in high-density cultures. Toxicol Sci 121, 73-87. doi:10.1093/toxsci/kfr034
-
(2011)
Toxicol Sci
, vol.121
, pp. 73-87
-
-
Stiegler, N. V.1
Krug, A. K.2
Matt, F.3
Leist, M.4
-
72
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson, J. A., Itskovitz-Eldor, J., Shapiro, S. S. et al. (1998). Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147. doi:10.1126/science.282.5391. 1145
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J. A.1
Itskovitz-Eldor, J.2
Shapiro, S. S.3
-
73
-
-
84879599189
-
Improving the human hazard characterization of chemicals: A Tox21 update
-
Tice, R. R., Austin, C. P., Kavlock, R. J. and Bucher, J. R. (2013). Improving the human hazard characterization of chemicals: A Tox21 update. Environ Health Perspect 121, 756-765. doi:10.1289/ehp.1205784
-
(2013)
Environ Health Perspect
, vol.121
, pp. 756-765
-
-
Tice, R. R.1
Austin, C. P.2
Kavlock, R. J.3
Bucher, J. R.4
-
74
-
-
84864511648
-
Translating neurobehavioural endpoints of developmental neurotoxicity tests into in vitro assays and readouts
-
van Thriel, C., Westerink, R. H., Beste, C. et al. (2012). Translating neurobehavioural endpoints of developmental neurotoxicity tests into in vitro assays and readouts. Neurotoxicology 33, 911-924. doi:10.1016/j.neuro.2011.10.002
-
(2012)
Neurotoxicology
, vol.33
, pp. 911-924
-
-
van Thriel, C.1
Westerink, R. H.2
Beste, C.3
-
75
-
-
38549151817
-
Drugbank: A knowledgebase for drugs, drug actions and drug targets
-
Wishart, D. S., Knox, C., Guo, A. C. et al. (2008). Drugbank: A knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res 36, D901-D906. doi:10.1093/nar/gkm958
-
(2008)
Nucleic Acids Res
, vol.36
, pp. D901-D906
-
-
Wishart, D. S.1
Knox, C.2
Guo, A. C.3
-
76
-
-
84894262438
-
PCB 136 atropselectively alters morphometric and functional parameters of neuronal connectivity in cultured rat hippocampal neurons via ryanodine receptor-dependent mechanisms
-
Yang, D., Kania-Korwel, I., Ghogha, A. et al. (2014). PCB 136 atropselectively alters morphometric and functional parameters of neuronal connectivity in cultured rat hippocampal neurons via ryanodine receptor-dependent mechanisms. Toxicol Sci 138, 379-392. doi:10.1093/toxsci/kft334
-
(2014)
Toxicol Sci
, vol.138
, pp. 379-392
-
-
Yang, D.1
Kania-Korwel, I.2
Ghogha, A.3
-
77
-
-
79951678616
-
Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing
-
Zimmer, B., Kuegler, P. B., Baudis, B. et al. (2011a). Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing. Cell Death Differ 18, 383-395. doi:10.1038/cdd.2010.109
-
(2011)
Cell Death Differ
, vol.18
, pp. 383-395
-
-
Zimmer, B.1
Kuegler, P. B.2
Baudis, B.3
-
78
-
-
79957868414
-
Sensitivity of dopaminergic neuron differentiation from stem cells to chronic low-dose methylmercury exposure
-
Zimmer, B., Schildknecht, S., Kuegler, P. B. et al. (2011b). Sensitivity of dopaminergic neuron differentiation from stem cells to chronic low-dose methylmercury exposure. Toxicol Sci 121, 357-367. doi:10.1093/toxsci/kfr054
-
(2011)
Toxicol Sci
, vol.121
, pp. 357-367
-
-
Zimmer, B.1
Schildknecht, S.2
Kuegler, P. B.3
-
79
-
-
84864758119
-
Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cells
-
Zimmer, B., Lee, G., Balmer, N. V. et al. (2012). Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cells. Environ Health Perspect 120, 1116-1122. doi:10.1289/ ehp.1104489
-
(2012)
Environ Health Perspect
, vol.120
, pp. 1116-1122
-
-
Zimmer, B.1
Lee, G.2
Balmer, N. V.3
-
80
-
-
84901307535
-
Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery
-
Zimmer, B., Pallocca, G., Dreser, N. et al. (2014). Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery. Arch Toxicol 88, 1109-1126. doi:10.1007/s00204-014-1231-9
-
(2014)
Arch Toxicol
, vol.88
, pp. 1109-1126
-
-
Zimmer, B.1
Pallocca, G.2
Dreser, N.3
|